CN109481810A - A kind of continuous controlled release drug administration type tracheal catheter - Google Patents
A kind of continuous controlled release drug administration type tracheal catheter Download PDFInfo
- Publication number
- CN109481810A CN109481810A CN201811546635.6A CN201811546635A CN109481810A CN 109481810 A CN109481810 A CN 109481810A CN 201811546635 A CN201811546635 A CN 201811546635A CN 109481810 A CN109481810 A CN 109481810A
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- China
- Prior art keywords
- tracheal catheter
- medicine
- wall
- drug administration
- controlled release
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- 238000013270 controlled release Methods 0.000 title claims abstract description 13
- 238000001647 drug administration Methods 0.000 title claims abstract description 13
- 239000002775 capsule Substances 0.000 claims abstract description 22
- 241000459479 Capsula Species 0.000 claims abstract description 20
- 238000000034 method Methods 0.000 claims description 8
- 206010036790 Productive cough Diseases 0.000 claims description 7
- 208000024794 sputum Diseases 0.000 claims description 7
- 210000003802 sputum Anatomy 0.000 claims description 7
- 230000036407 pain Effects 0.000 abstract description 3
- 239000003814 drug Substances 0.000 description 11
- 229940079593 drug Drugs 0.000 description 11
- 206010002091 Anaesthesia Diseases 0.000 description 6
- 230000037005 anaesthesia Effects 0.000 description 6
- 238000001949 anaesthesia Methods 0.000 description 5
- 206010062717 Increased upper airway secretion Diseases 0.000 description 4
- 208000026435 phlegm Diseases 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 210000004877 mucosa Anatomy 0.000 description 3
- 230000000638 stimulation Effects 0.000 description 3
- 230000003115 biocidal effect Effects 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 239000010903 husk Substances 0.000 description 1
- 239000010687 lubricating oil Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000002550 vasoactive agent Substances 0.000 description 1
- 230000002227 vasoactive effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/04—Tracheal tubes
- A61M16/0486—Multi-lumen tracheal tubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/04—Tracheal tubes
- A61M16/0402—Special features for tracheal tubes not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M19/00—Local anaesthesia; Hypothermia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0468—Liquids non-physiological
- A61M2202/048—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/10—Trunk
- A61M2210/1025—Respiratory system
- A61M2210/1032—Trachea
Landscapes
- Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention discloses a kind of continuous controlled release drug administration type tracheal catheter, including tracheal catheter, gas tube, medicine-pouring pipe, inflatable cuff;One end of the tracheal catheter is equipped with seam, and the other end is equipped with the inflatable cuff;The inflatable cuff is made of capsula interna and the external capsule being coated on outside capsula interna, wherein the external capsule is made of the control release film of medical grade;The gas tube and the medicine-pouring pipe are all connected with the tube wall of the tracheal catheter and bury in its wall layers;The gas tube along the axially extending of tracheal catheter and be formed by cavity with the capsula interna and be connected in the wall layers of tracheal catheter;The medicine-pouring pipe along the axially extending of tracheal catheter and be formed by cavity with the external capsule and be connected in the wall layers of tracheal catheter.The more diversification of the function of tracheal catheter provided by the invention, and then more demands can be suitble to, the generation of malpractice is reduced, the pain of patient is reduced.
Description
Technical field
The present invention relates to medical instruments field, specifically a kind of continuous controlled release drug administration type tracheal catheter.
Background technique
Tracheal catheter is anesthesia, first aid, the indispensable product of Intensive Care Therapy, stimulation of the existing tracheal catheter to patient
Very big, especially when tracheal catheter is placed in and is extracted, the stress reaction for usually causing patient violent, clinic is commonly used in tracheae and leads
The mode that local anaesthesia drug is smeared on tube airbag surface reduces the stimulation to patient, still, can not be again after tracheal catheter is placed in tracheae
Secondary smearing local anaesthesia drug, and tracheal catheter needs the time of indwelling in patient airway long, the local anaesthesia drug smeared in advance
Drug effect fades away, and in tube drawing, the stress reaction that strong impulse can cause patient violent again jeopardizes patient safety.In addition,
For certain patients, after indwelling tracheal catheter, certain specific drugs, such as vasoactive can be given via tracheal catheter
Medicine, hormone, antibiotic etc., and sometimes for slow administration so that patient's blood concentration is steady, and existing tracheal catheter
It is unable to satisfy this requirement.
Summary of the invention
The purpose of the present invention is to provide a kind of continuous controlled release drug administration type tracheal catheters, can be needed according to clinic at any time by gas
Pipe conduit is administered into patient airway, and can control the rate of release of given drug, to solve to propose in above-mentioned background technique
The problem of.
In order to solve the above-mentioned technical problem, the technical solution adopted by the present invention is that:
A kind of continuous controlled release drug administration type tracheal catheter, including tracheal catheter, gas tube, medicine-pouring pipe, inflatable cuff;
One end of the tracheal catheter is equipped with seam, and the other end is equipped with the inflatable cuff;
The inflatable cuff is made of capsula interna and the external capsule being coated on outside capsula interna, wherein the external capsule is using medical
The control release film of grade is made;
The gas tube and the medicine-pouring pipe are all connected with the tube wall of the tracheal catheter and bury in its wall layers;
The gas tube in the wall layers of tracheal catheter along the axially extending of tracheal catheter and with the capsula interna institute shape
At cavity connection;
The medicine-pouring pipe in the wall layers of tracheal catheter along the axially extending of tracheal catheter and with the external capsule institute shape
At cavity connection.
Preferably, the inner wall of the tracheal catheter uses superslide process, in order to be inserted into suction sputum in tracheal catheter
Pipe.
Further, the gas tube is equipped with charge valve far from one end of the tracheal catheter.
Further, the medicine-pouring pipe is equipped with medicine-pouring port far from one end of the tracheal catheter, and is equipped with and keeps medicine-pouring port
Clean lid mouth.
Further, it is into body end that the tracheal catheter, which is equipped with one end of inflatable cuff, and the tracheal catheter passes through inflation
Cuff, and the capsula interna lateral wall seamless binding of its outer wall and inflatable cuff.
The beneficial effects of the present invention are: the present invention provides a kind of continuous controlled release drug administration type tracheal catheter, structure is simple, new
Grain husk, by setting capsula interna and external capsule two parts for inflatable cuff, capsula interna is connected to gas tube and ventilates, external capsule and medicine-pouring pipe
Connection carries out injection, and external capsule is made of the control release film of medical grade, and then it is medical that the medical fluid in medicine-pouring pipe can be made to pass through
Micropore on the control release film of grade is slowly penetrated into tunica mucosa tracheae, and realizing can be through gas while indwelling tracheal catheter
Pipe catheter drug delivery.Simultaneously as the aperture of the micropore on film and quantity can be according to clinical need when producing this kind control release film
The difference asked and different from, and the aperture size and controllable quantity.By such improved procedure, the given drug of transtracheal catheters
Onset time and the duration it is entirely controlled, make the function more diversification of tracheal catheter.It can be by preparing specific release
The film of speed reduces the generation of malpractice to meet different clinical demands, reduces the pain of patient.Meanwhile gas tube
It is buried in the wall layers of tracheal catheter with medicine-pouring pipe, is not take up the inner space of tracheal catheter, such as need to draw to the later period
When phlegm in patient airway, protruding into for sputum aspirator tube is not interfered.
Detailed description of the invention
The present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.
Fig. 1 is schematic structural view of the invention.
Fig. 2 is the partial schematic diagram that tracheal catheter is connect with inflatable cuff.
In figure: 1, tracheal catheter, 2, gas tube, 3, medicine-pouring pipe, 4, inflatable cuff, 41, capsula interna, 42, external capsule, 5, linking
Mouthful, 6, charge valve, 7, medicine-pouring port, 8, Gai Kou, 9, enter body end.
Specific embodiment
Technical solution of the present invention is clearly and completely described below in conjunction with attached drawing, it is clear that described implementation
Example is a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, ordinary skill
Personnel's every other embodiment obtained without making creative work, shall fall within the protection scope of the present invention.
As shown in Figs. 1-2, the present invention provides a kind of continuous controlled release drug administration type tracheal catheter, including tracheal catheter 1, gas tube
2, medicine-pouring pipe 3, inflatable cuff 4;
One end of the tracheal catheter 1 is equipped with seam 5, and the other end is equipped with the inflatable cuff 4;
The inflatable cuff 4 is made of capsula interna 41 and the external capsule being coated on outside capsula interna 41 42, wherein the external capsule 42
It is made of the control release film of medical grade;
The gas tube 2 is all connected with the tube wall of the tracheal catheter 1 and buries in its wall layers with the medicine-pouring pipe 3
In;
The gas tube 2 in the wall layers of tracheal catheter 1 along the axially extending of tracheal catheter 1 and with the capsula interna 41
It is formed by cavity connection;
The medicine-pouring pipe 3 in the wall layers of tracheal catheter 1 along the axially extending of tracheal catheter 1 and with the external capsule 42
It is formed by cavity connection.
The inner wall of the tracheal catheter 1 uses superslide process, in order to be inserted into sputum aspirator tube in tracheal catheter 1, inhales
Absorption will not be generated between phlegm pipe and the inside of the use superslide process of tracheal catheter 1, protrudes into target position convenient for sputum aspirator tube,
It when having phlegm in the tracheae of patient, can be inserted directly into, without still further again in suction sputum pipe outer wall coating lubricating oil.
The gas tube 2 is equipped with charge valve 6 far from one end of the tracheal catheter 1.
The medicine-pouring pipe 3 is equipped with medicine-pouring port 7 far from one end of the tracheal catheter 1, and is equipped with and keeps medicine-pouring port 7 clean
Lid mouth 8.
One end that the tracheal catheter 1 is equipped with inflatable cuff 4 is into body end 9, and the tracheal catheter 1 passes through inflatable cuff 4,
And the 41 lateral wall seamless binding of capsula interna of its outer wall and inflatable cuff 4.
Capsula interna 41 that the present invention is arranged by inflatable cuff, 42 structure of external capsule, capsula interna 41 is connected to gas tube 2 to be led to
Gas, external capsule 42 is connected to medicine-pouring pipe 3 carries out injection, and external capsule 42 is made of the control release film of medical grade, and then can make to infuse
The micropore on control release film that medical fluid in pencil 3 passes through medical grade is slowly penetrated into tunica mucosa tracheae, is realized in indwelling
It can be administered while tracheal catheter 1 with transtracheal catheters 1.Simultaneously as micropore when producing this kind control release film, on film
Aperture and quantity can according to the difference of clinical demand different from, and the aperture size and controllable quantity.Changed by such
Into mode, the onset time and duration of the given drug of transtracheal catheters 1 are entirely controlled, make the function of tracheal catheter 1 more
Diversification.The generation of malpractice can be reduced to meet different clinical demands by preparing the film of specific rate of release,
Reduce the pain of patient.Meanwhile gas tube 2 and medicine-pouring pipe 3 bury in the wall layers of tracheal catheter 1, are not take up tracheae
The inner space of conduit 1 when such as needing to draw the phlegm in patient airway to the later period, does not interfere protruding into for sputum aspirator tube.
Application method: being placed in as existing tracheal catheter, after merging, can before Extubation in Patients and when Sobering belt pipe,
Local anaesthesia drug through medicine-pouring port injection doses, local anaesthesia drug slow release anaesthetize the tunica mucosa tracheae outside capsule, mitigate tracheae and lead
Stimulation of the pipe to tracheae, substantially reduces the stress reaction of patient.It similarly, can be via tracheal catheter for certain particular patients
Medicine-pouring port gives certain specific drugs, such as vasoactive drug, hormone, antibiotic etc., meets specific clinical demand.
The embodiments of the present invention described above are not intended to limit the scope of the present invention, any in the present invention
Spirit and principle within made modifications, equivalent substitutions and improvements etc., should be included in claim protection model of the invention
Within enclosing.
Claims (5)
1. a kind of continuous controlled release drug administration type tracheal catheter, which is characterized in that including tracheal catheter, gas tube, medicine-pouring pipe, inflation set
Capsule;
One end of the tracheal catheter is equipped with seam, and the other end is equipped with the inflatable cuff;
The inflatable cuff is made of capsula interna and the external capsule being coated on outside capsula interna, wherein the external capsule is using medical grade
Control release film is made;
The gas tube and the medicine-pouring pipe are all connected with the tube wall of the tracheal catheter and bury in its wall layers;
The gas tube is formed by along the axially extending of tracheal catheter in the wall layers of tracheal catheter and with the capsula interna
Cavity connection;
The medicine-pouring pipe is formed by along the axially extending of tracheal catheter in the wall layers of tracheal catheter and with the external capsule
Cavity connection.
2. continuous controlled release drug administration type tracheal catheter according to claim 1, which is characterized in that the inner wall of the tracheal catheter
Using superslide process, in order to be inserted into sputum aspirator tube in tracheal catheter.
3. continuous controlled release drug administration type tracheal catheter according to claim 1, which is characterized in that the gas tube is far from described
One end of tracheal catheter is equipped with charge valve.
4. continuous controlled release drug administration type tracheal catheter according to claim 1, which is characterized in that the medicine-pouring pipe is far from described
One end of tracheal catheter is equipped with medicine-pouring port, and is equipped with and keeps the clean lid mouth of medicine-pouring port.
5. continuous controlled release drug administration type tracheal catheter according to claim 1, which is characterized in that the tracheal catheter, which is equipped with, to be filled
One end of air-casing capsule is into body end, and the tracheal catheter passes through inflatable cuff, and on the outside of its outer wall and the capsula interna of inflatable cuff
Wall seamless bonding.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201811546635.6A CN109481810A (en) | 2018-12-18 | 2018-12-18 | A kind of continuous controlled release drug administration type tracheal catheter |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201811546635.6A CN109481810A (en) | 2018-12-18 | 2018-12-18 | A kind of continuous controlled release drug administration type tracheal catheter |
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Publication Number | Publication Date |
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CN109481810A true CN109481810A (en) | 2019-03-19 |
Family
ID=65710634
Family Applications (1)
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CN201811546635.6A Pending CN109481810A (en) | 2018-12-18 | 2018-12-18 | A kind of continuous controlled release drug administration type tracheal catheter |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112244957A (en) * | 2020-10-29 | 2021-01-22 | 安徽省立医院(中国科学技术大学附属第一医院) | Continuous slow-release administration indwelling tube with puncture sheath |
CN112274747A (en) * | 2020-10-29 | 2021-01-29 | 合肥达米医疗科技有限公司 | Double-layer sac tracheal catheter |
CN112274745A (en) * | 2020-10-29 | 2021-01-29 | 合肥达米医疗科技有限公司 | Double-layer bag double-cavity bronchial catheter |
CN112274746A (en) * | 2020-10-29 | 2021-01-29 | 合肥达米医疗科技有限公司 | Double-layer sac tracheotomy sleeve |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN2912672Y (en) * | 2005-06-28 | 2007-06-20 | 兀效儒 | Multifunction trachea guide tube with two overlapping capsules |
-
2018
- 2018-12-18 CN CN201811546635.6A patent/CN109481810A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN2912672Y (en) * | 2005-06-28 | 2007-06-20 | 兀效儒 | Multifunction trachea guide tube with two overlapping capsules |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112244957A (en) * | 2020-10-29 | 2021-01-22 | 安徽省立医院(中国科学技术大学附属第一医院) | Continuous slow-release administration indwelling tube with puncture sheath |
CN112274747A (en) * | 2020-10-29 | 2021-01-29 | 合肥达米医疗科技有限公司 | Double-layer sac tracheal catheter |
CN112274745A (en) * | 2020-10-29 | 2021-01-29 | 合肥达米医疗科技有限公司 | Double-layer bag double-cavity bronchial catheter |
CN112274746A (en) * | 2020-10-29 | 2021-01-29 | 合肥达米医疗科技有限公司 | Double-layer sac tracheotomy sleeve |
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Application publication date: 20190319 |
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