CN112274745A - Double-layer bag double-cavity bronchial catheter - Google Patents

Double-layer bag double-cavity bronchial catheter Download PDF

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Publication number
CN112274745A
CN112274745A CN202011183404.0A CN202011183404A CN112274745A CN 112274745 A CN112274745 A CN 112274745A CN 202011183404 A CN202011183404 A CN 202011183404A CN 112274745 A CN112274745 A CN 112274745A
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China
Prior art keywords
slow
bronchial
tube
bag
release
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Pending
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CN202011183404.0A
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Chinese (zh)
Inventor
夏敏
王胜
谭斌
吴舟
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Hefei Dami Medical Science & Technology Co ltd
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Hefei Dami Medical Science & Technology Co ltd
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Priority to CN202011183404.0A priority Critical patent/CN112274745A/en
Publication of CN112274745A publication Critical patent/CN112274745A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/04Tracheal tubes
    • A61M16/0488Mouthpieces; Means for guiding, securing or introducing the tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

The invention provides a double-bag double-cavity bronchial catheter which comprises a double-cavity bronchial catheter body, wherein the double-cavity bronchial catheter body comprises a first bronchial catheter and a second bronchial catheter which are mutually isolated in air path, the outer sides of the tube walls of the first bronchial catheter and the second bronchial catheter are respectively and correspondingly provided with a first air bag and a second air bag, the outer side of the first air bag is also provided with a first slow-release bag, liquid medicine can be input into an interlayer cavity formed by the first slow-release bag and the first air bag, and the liquid medicine can be seeped to the outer side of the first slow-release bag. The double-layer-bag double-cavity bronchial catheter can control the release speed of the administered drug through the slow release effect of the slow release bag so as to achieve slow, uniform and continuous administration, can relieve the stimulation of the catheter to the trachea after the catheter is placed, and greatly reduces the stress response of a patient.

Description

Double-layer bag double-cavity bronchial catheter
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to a double-layer-bag double-cavity bronchial catheter.
Background
The double-cavity bronchial catheter is a necessary airway tool for a lung isolation technology and is widely applied to anesthesia and emergency treatment, the existing double-cavity bronchial catheter has very large stimulation to a patient, particularly, when the catheter is placed in and pulled out, severe stress reaction of the patient is often caused, the stimulation to the patient is reduced by a mode of smearing local anesthetic on the surface of an air bag of the tracheal catheter in common clinical use, however, after the catheter is placed in a trachea, the local anesthetic cannot be smeared again, the time for the catheter to be detained in the trachea of the patient is long, the drug effect of the local anesthetic smeared in advance is gradually lost, and when the catheter is pulled out, the severe stimulation can cause the severe stress reaction of the patient, so that the safety of the patient is endangered. In addition, for some patients, after the catheter is placed, some specific drugs, such as vasoactive drugs, hormones, antibiotics and the like, can be administered through the catheter, and sometimes slow administration is needed to stabilize the blood concentration of the patients, and most of the existing double-lumen bronchial catheters cannot meet the requirement.
Disclosure of Invention
Therefore, the technical problem to be solved by the invention is to provide a double-bag double-cavity bronchial catheter, which can control the release speed of the administered drug through the slow release effect of the slow release bag so as to achieve slow, uniform and continuous administration, and can alleviate the stimulation of the catheter to the trachea after the catheter is placed, thereby greatly reducing the stress response of a patient.
In order to solve the above problems, the present invention provides a double-balloon double-lumen bronchial catheter, comprising a double-lumen bronchial catheter body, the double-cavity bronchial catheter body comprises a first bronchial catheter and a second bronchial catheter which are mutually isolated in gas path, the outer sides of the tube walls of the first bronchial catheter and the second bronchial catheter are respectively and correspondingly provided with a first air bag and a second air bag, a first slow-release bag is further arranged on the outer side of the first air bag, liquid medicine can be input into an interlayer cavity formed by the first slow-release bag and the first air bag, the liquid medicine can seep out of the first slow-release bag, and/or a second slow-release bag is further arranged on the outer side of the second air bag, liquid medicine can be input into an interlayer cavity formed by the second slow-release bag and the second air bag, and the liquid medicine can seep out of the second slow-release bag.
Preferably, the first and second slow-release capsules are independent of each other or communicate with each other.
Preferably, the double-layer-sac double-cavity bronchial catheter further comprises a medicine injection pipe, and an outlet of the medicine injection pipe is communicated with the first slow-release sac and/or the second slow-release sac.
Preferably, the drug injection tube is at least partially within the wall of the first bronchial tube or the second bronchial tube.
Preferably, the inlet of the medicine injection tube is provided with a medicine storage bag, and the medicine storage bag is provided with a medicine injection port.
Preferably, a check valve is arranged in the medicine injection port; and/or the medicine storage bag is made of an elastic material so as to force the liquid medicine in the medicine storage bag into the medicine injection pipe by utilizing the elastic retraction of the medicine storage bag.
Preferably, the drug injection port is in through connection with the drug storage bag through a connecting pipe.
Preferably, the first slow release capsule and/or the second slow release capsule are/is made of medical hydrophilic and hydrophobic nano composite materials.
Preferably, the medical hydrophilic and hydrophobic nanocomposite comprises one of a fluoropolymer and a polyurethane.
Preferably, the inner wall of the tube of the first bronchial tube and/or the second bronchial tube is rounded.
After the double-layer bag double-cavity bronchial catheter is placed, liquid medicine can be input into the slow release bag before the patient pulls out the catheter and when the patient is in a waking state, and then the liquid medicine slowly, uniformly and continuously seeps out of the mucous membrane of the trachea outside the wall of the slow release bag through the wall of the slow release bag under the action of the slow release bag, so that the irritation of the catheter to the trachea is relieved, and the stress response of the patient is greatly reduced.
Drawings
Fig. 1 is a schematic structural view of a double-balloon double-lumen bronchial catheter in accordance with an embodiment of the present invention.
The reference numerals are represented as:
11. a first bronchial tube; 12. a second bronchial tube; 13. a first air bag; 14. a second air bag; 15. a double pipe joint; 16. a first air bag inflation line; 17. a second airbag inflation line; 21. a first sustained release capsule; 22. a second delay capsule; 23. a medicine injection tube; 24. a medicine storage bag; 241. a medicine injection port; 242. and (4) connecting the pipes.
Detailed Description
Referring to fig. 1, according to an embodiment of the present invention, there is provided a double-balloon double-lumen bronchial catheter, including a double-lumen bronchial catheter body, where the double-lumen bronchial catheter body includes a first bronchial catheter 11 and a second bronchial catheter 12 that are isolated from each other by gas circuits, the outer sides of the tube walls of the first bronchial catheter 11 and the second bronchial catheter 12 are respectively and correspondingly provided with a first balloon 13 and a second balloon 14, the first balloon 13 is communicated with a first balloon inflation pipeline 16, the second balloon 14 is communicated with a second balloon inflation pipeline 17, the inlets of the first bronchial catheter 11 and the second bronchial catheter 12 are connected with a double-tube connector 15, the outer side of the first balloon 13 is further provided with a first slow-release balloon 21, a liquid medicine can be input into an interlayer cavity formed by the first slow-release balloon 21 and the first balloon 13, and the liquid medicine can seep to the outer side of the first slow-release balloon 21, and/or a second slow-release bag 22 is further arranged on the outer side of the second air bag 14, a liquid medicine can be input into an interlayer cavity formed by the second slow-release bag 22 and the second air bag 14, and the liquid medicine can seep out of the second slow-release bag 22 to the outer side thereof. The double-layer bag double-cavity bronchial catheter is the same as the existing double-layer bronchial catheter in the aspect of catheter implantation, after the catheter is implanted, liquid medicine can be input into the slow release bag before the patient pulls out the catheter and when the patient is in a sobering belt, and then the liquid medicine slowly, uniformly and continuously seeps out of the wall of the slow release bag to the mucosa of the tracheal tube outside the wall of the bag under the action of the slow release bag, so that the stimulation of the catheter to the trachea is relieved, and the stress response of the patient is greatly reduced. The first slow-release capsule 21 and the second slow-release capsule 22 are independent from each other or are communicated with each other.
As one embodiment, preferably, the double-balloon dual-lumen bronchial catheter further comprises a drug injection tube 23, an outlet of the drug injection tube 23 is communicated with the first slow-release balloon 21 and/or the second slow-release balloon 22, and a drug solution is infused into the first slow-release balloon 21 or the second slow-release balloon 22 through the drug injection tube 23.
The medicine injection tube 23 is at least partially located in the wall body of the first bronchial tube 11 or the second bronchial tube 12, specifically, the medicine injection tube 23 is arranged on the corresponding tube section of the tube inserted into the patient body and located in the wall body of the first bronchial tube 11 or the second bronchial tube 12, so that the tube is more compact in structure, and the stimulation of the independent external arrangement of the tube to the trachea of the patient is prevented.
Preferably, the inlet of the drug injection tube 23 is provided with a drug storage bag 24, the drug storage bag 24 is provided with a drug injection port 241, and the drug storage bag 24 is made of an elastic material so as to utilize the elastic retraction of the drug storage bag 24 to force the drug liquid therein into the drug injection tube 23. At this time, the external liquid medicine is input into the medicine storage bag 24 through the medicine injection port 241, and due to the elasticity of the medicine storage bag 24, the liquid medicine in the medicine storage bag 24 is conveyed to the interlayer cavity between the sustained release bag and the air bag along the medicine injection tube 23 under the action of the elastic retraction force of the medicine storage bag, and then the medicine slowly, uniformly and continuously seeps out to the mucosa of the outer trachea of the bag wall through the sustained release bag wall under the action of the retraction force. It should be further noted that the cooperation of the elastic medicine storage bag 24 and the first slow-release bag 21 or the second slow-release bag 22 makes the administration of the medicine more durable and uniform.
Preferably, the medicine storage bag 3 is made of an elastic material, and specifically, for example, one of silica gel, rubber, latex or nylon can be used, wherein the formable wall thickness of the silica gel is 0.2-0.4mm, the shore softness is 30, the medicine storage bag can be manufactured by injection molding or bonding technology, the elasticity is good, the product performance is stable, the medicine storage bag is transparent, and the medicine storage bag can be beneficial for an operator to observe the liquid medicine condition in the bag; the formable wall thickness of the rubber is 0.5-0.8mm, the Shore softness is 40, the formable wall can be manufactured by adopting an injection molding or bonding process, the formable wall has general elasticity, the appearance is rough, the hardness is high, the formable wall is mostly white, and the liquid medicine condition in the capsule can not be observed; the formable wall thickness of the latex is 0.2-1mm, the Shore softness is 20-30, the formable latex can be manufactured by adopting an injection molding or bonding process, the formable latex has moderate elasticity, the appearance is not fine and smooth enough, the formable latex is semitransparent, and the forming effect is not good; the wall thickness of the formable nylon is 0.2-0.6mm, the formable nylon can be manufactured by adopting a bonding process, the formable nylon has poor elasticity and is semitransparent, and therefore, the formable nylon is best, and the medicine storage bag 3 is made of silica gel.
A check valve is provided in the medicine injection port 241 to prevent the backflow of the medicine solution from leaking.
Preferably, the medicine injection port 241 is connected to the medicine storage bag 24 by a connection pipe 242, and the connection pipe 242 has flexibility, which facilitates the selection of the administration angle of the medical staff when administering the medicine into the medicine storage bag 24.
Preferably, the first slow release capsule 21 and/or the second slow release capsule 22 are/is made of medical hydrophilic and hydrophobic nano composite material, the medical hydrophilic and hydrophobic nano composite material comprises one of fluorine-containing polymer and polyurethane, and the pore diameter of a permeation hole on the slow release membrane is 1-100 nm.
Preferably, the inner wall of the first bronchial tube 11 and/or the second bronchial tube 12 is rounded to facilitate insertion of a sputum suction tube into the tube.
As a more preferable embodiment, the periphery of the first slow-release capsule 21 and/or the second slow-release capsule 22 may be optionally sleeved with a slow-release drug delivery positioning film sleeve (not shown in the figure), the slow-release drug delivery positioning film sleeve outside the through hole can prevent the drug solution in the first slow-release capsule 21 and/or the second slow-release capsule 22 from seeping out, and the through hole can allow the drug solution in the first slow-release capsule 21 and/or the second slow-release capsule 22 to seep out, so that the drug solution seeping out in the slow-release capsule 3 can be positioned to be suitable for the situation that sustained drug delivery is required for some punctate lesions.
It is readily understood by a person skilled in the art that the advantageous ways described above can be freely combined, superimposed without conflict.
The present invention is not limited to the above preferred embodiments, and any modifications, equivalent substitutions and improvements made within the spirit and principle of the present invention should be included in the protection scope of the present invention. The above is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, several improvements and modifications can be made without departing from the technical principle of the present invention, and these improvements and modifications should also be regarded as the protection scope of the present invention.

Claims (10)

1. The utility model provides a double-deck bag two-chamber bronchial tube, includes two-chamber bronchial tube body, two-chamber bronchial tube body includes first bronchial tube (11), second bronchial tube (12) that mutual gas circuit keeps apart, first bronchial tube (11) and the pipe wall outside of second bronchial tube (12) corresponds respectively and is equipped with first gasbag (13), second gasbag (14), its characterized in that, the outside of first gasbag (13) still is equipped with first slow-release bag (21), can input the liquid medicine in first slow-release bag (21) and the intermediate layer chamber that first gasbag (13) formed, the liquid medicine can ooze to its outside via first slow-release bag (21), and/or, the outside of second gasbag (14) still is equipped with second slow-release bag (22), can input the liquid medicine in second slow-release bag (22) and the intermediate layer chamber that second gasbag (14) formed, the liquid medicine can seep out to the outside of the second slow-release capsule (22).
2. Bronchial catheter according to claim 1, characterized in that said first slow-release capsule (21) and said second slow-release capsule (22) are independent from each other or communicate with each other.
3. Bronchial catheter according to claim 1, characterized in that it further comprises a drug injection tube (23), the outlet of said drug injection tube (23) being in communication with said first and/or second slow-release capsule (21, 22).
4. Bronchial tube according to claim 3, characterized in that the drug injection tube (23) is at least partially inside the wall of the first bronchial tube (11) or the second bronchial tube (12).
5. The bronchial tube as set forth in claim 3, wherein the inlet of the drug injection tube (23) is provided with a drug storage bag (24), the drug storage bag (24) having a drug injection port (241) thereon.
6. Bronchial catheter according to claim 5, characterized in that a non-return valve is provided in the injection port (241); and/or the medicine storage bag (24) is made of an elastic material so as to utilize the elastic retraction of the medicine storage bag (24) to force the liquid medicine in the medicine storage bag into the medicine injection pipe (23).
7. The indwelling tube according to claim 5, wherein the injection port (241) is in through connection with the drug reservoir (24) by means of a connecting tube (242).
8. Bronchial catheter according to claim 1, characterized in that said first (21) and/or second (22) sustained-release capsules are made of medical hydrophilic and hydrophobic nanocomposites.
9. The bronchial catheter of claim 8, wherein the medical hydrophilic and hydrophobic nanocomposite comprises one of a fluoropolymer and a polyurethane.
10. Bronchial tube according to claim 1, characterized in that the inner tube wall of the first bronchial tube (11) and/or the second bronchial tube (12) is rounded.
CN202011183404.0A 2020-10-29 2020-10-29 Double-layer bag double-cavity bronchial catheter Pending CN112274745A (en)

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CN202011183404.0A CN112274745A (en) 2020-10-29 2020-10-29 Double-layer bag double-cavity bronchial catheter

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Application Number Priority Date Filing Date Title
CN202011183404.0A CN112274745A (en) 2020-10-29 2020-10-29 Double-layer bag double-cavity bronchial catheter

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CN112274745A true CN112274745A (en) 2021-01-29

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Citations (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0383429A2 (en) * 1989-01-31 1990-08-22 C.R. Bard, Inc. Catheter and method for locally applying medication to the wall of a blood vessel or other body lumen
WO1992011895A1 (en) * 1990-12-28 1992-07-23 Boston Scientific Corporation Balloon drug delivery system
JPH0898893A (en) * 1994-09-29 1996-04-16 Terumo Corp Medicine dosing catheter
US5985307A (en) * 1993-04-14 1999-11-16 Emory University Device and method for non-occlusive localized drug delivery
EP1974766A1 (en) * 2007-03-29 2008-10-01 Zahid Hussain Khan Multilayer cuff
WO2010118882A1 (en) * 2009-04-18 2010-10-21 Qualimed Innovative Medizinprodukte Gmbh Balloon catheter
CN102271750A (en) * 2008-11-14 2011-12-07 明诺医学股份有限公司 Selective drug delivery in a lumen
CN202490297U (en) * 2011-12-27 2012-10-17 高宏 Double-cavity bronchial catheter capable of dosing continuously in airway
US20140364834A1 (en) * 2013-06-10 2014-12-11 Cook Medical Technologies Llc Weeping Balloon Catheter With Drug Delivery Through Dilation Balloon
CN104857615A (en) * 2014-02-26 2015-08-26 常州乐奥医疗科技有限公司 Novel dual-layer drug balloon catheter
US9242005B1 (en) * 2006-08-21 2016-01-26 Abbott Cardiovascular Systems Inc. Pro-healing agent formulation compositions, methods and treatments
CN106390268A (en) * 2016-10-21 2017-02-15 复旦大学附属中山医院 Expansible and infusable balloon catheter
US20170266421A1 (en) * 2013-01-15 2017-09-21 Krishna Rocha-Singh Apparatus and method for delivering intraluminal therapy
CN107303406A (en) * 2016-04-21 2017-10-31 青岛智辰生物科技有限公司 A kind of sacculus dilating catheter
CN207755617U (en) * 2017-05-27 2018-08-24 无锡市第四人民医院 A kind of dual cavity bronchus vessel being administered
CN108853690A (en) * 2018-08-14 2018-11-23 张海军 A kind of film envelope drug storage sacculus and preparation method
CN109260559A (en) * 2018-09-11 2019-01-25 厦门仁人医疗科技有限公司 A kind of tracheal inserting device
CN109481810A (en) * 2018-12-18 2019-03-19 柳兆芳 A kind of continuous controlled release drug administration type tracheal catheter
CN109938893A (en) * 2017-12-18 2019-06-28 上海微创医疗器械(集团)有限公司 Sacculus dilating catheter and its medicinal balloon
CN110732078A (en) * 2019-11-14 2020-01-31 昆山金泰医疗科技有限公司 Balloon
CN111330137A (en) * 2018-12-17 2020-06-26 深圳市擎源医疗器械有限公司 Drug delivery device
CN211068565U (en) * 2019-08-14 2020-07-24 复旦大学附属眼耳鼻喉科医院 Tracheotomy sleeve capable of slowly releasing medicine

Patent Citations (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0383429A2 (en) * 1989-01-31 1990-08-22 C.R. Bard, Inc. Catheter and method for locally applying medication to the wall of a blood vessel or other body lumen
WO1992011895A1 (en) * 1990-12-28 1992-07-23 Boston Scientific Corporation Balloon drug delivery system
US5985307A (en) * 1993-04-14 1999-11-16 Emory University Device and method for non-occlusive localized drug delivery
JPH0898893A (en) * 1994-09-29 1996-04-16 Terumo Corp Medicine dosing catheter
US9242005B1 (en) * 2006-08-21 2016-01-26 Abbott Cardiovascular Systems Inc. Pro-healing agent formulation compositions, methods and treatments
EP1974766A1 (en) * 2007-03-29 2008-10-01 Zahid Hussain Khan Multilayer cuff
CN102271750A (en) * 2008-11-14 2011-12-07 明诺医学股份有限公司 Selective drug delivery in a lumen
WO2010118882A1 (en) * 2009-04-18 2010-10-21 Qualimed Innovative Medizinprodukte Gmbh Balloon catheter
CN202490297U (en) * 2011-12-27 2012-10-17 高宏 Double-cavity bronchial catheter capable of dosing continuously in airway
US20170266421A1 (en) * 2013-01-15 2017-09-21 Krishna Rocha-Singh Apparatus and method for delivering intraluminal therapy
US20140364834A1 (en) * 2013-06-10 2014-12-11 Cook Medical Technologies Llc Weeping Balloon Catheter With Drug Delivery Through Dilation Balloon
CN104857615A (en) * 2014-02-26 2015-08-26 常州乐奥医疗科技有限公司 Novel dual-layer drug balloon catheter
CN107303406A (en) * 2016-04-21 2017-10-31 青岛智辰生物科技有限公司 A kind of sacculus dilating catheter
CN106390268A (en) * 2016-10-21 2017-02-15 复旦大学附属中山医院 Expansible and infusable balloon catheter
CN207755617U (en) * 2017-05-27 2018-08-24 无锡市第四人民医院 A kind of dual cavity bronchus vessel being administered
CN109938893A (en) * 2017-12-18 2019-06-28 上海微创医疗器械(集团)有限公司 Sacculus dilating catheter and its medicinal balloon
CN108853690A (en) * 2018-08-14 2018-11-23 张海军 A kind of film envelope drug storage sacculus and preparation method
CN109260559A (en) * 2018-09-11 2019-01-25 厦门仁人医疗科技有限公司 A kind of tracheal inserting device
CN111330137A (en) * 2018-12-17 2020-06-26 深圳市擎源医疗器械有限公司 Drug delivery device
CN109481810A (en) * 2018-12-18 2019-03-19 柳兆芳 A kind of continuous controlled release drug administration type tracheal catheter
CN211068565U (en) * 2019-08-14 2020-07-24 复旦大学附属眼耳鼻喉科医院 Tracheotomy sleeve capable of slowly releasing medicine
CN110732078A (en) * 2019-11-14 2020-01-31 昆山金泰医疗科技有限公司 Balloon

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