CN219824234U

CN219824234U - Stem cell incubator

Info

Publication number: CN219824234U
Application number: CN202320524358.9U
Authority: CN
Inventors: 于洋; 周平; 乔杰; 李蓉; 潘恒
Original assignee: Peking University Third Hospital Peking University Third Clinical Medical College
Current assignee: Peking University Third Hospital Peking University Third Clinical Medical College
Priority date: 2023-03-13
Filing date: 2023-03-13
Publication date: 2023-10-13
Anticipated expiration: 2033-03-13

Abstract

The utility model discloses a stem cell incubator, which comprises a shell and a shell door. According to the utility model, in the process of stirring nutrient solution, firstly, nutrient solution raw materials are added into the stirring barrel through the material port, then the control module is used for controlling and starting the double-shaft motor, the first gear at the right output end of the double-shaft motor is meshed with the transmission toothed ring, so that the stirring barrel can rotate inside the shell, the internal nutrient solution is conveniently stirred, bottom precipitation is not easy to be caused, meanwhile, on the basis of rotation of the right output shaft of the double-shaft motor, the left output shaft synchronously operates, so that the second gear on the left output shaft of the double-shaft motor is meshed with the third gear of the transmission stirrer through the toothed belt, and the stirrer can be conveniently driven to rotate inside the stirring barrel, further mixing stirring is carried out on the nutrient solution, precipitation is not easy to be caused, and further the stirring quality of the nutrient solution can be greatly improved.

Description

Stem cell incubator

Technical Field

The utility model belongs to the technical field of stem cell culture, and particularly relates to a stem cell incubator.

Background

Stem cells are a type of multipotent cells with self-replication capability, and can be differentiated into a plurality of functional cells under certain conditions, and when constant-temperature culture is needed, the cells are required to be placed into a constant-temperature container with adjustable temperature so as to meet the growth requirements.

A constant temperature stem cell culture vessel of patent publication number CN202222763913.1 searched by chinese patent net, the contents generally include: the box body is provided with a box door on the side wall of the bottom end of the box body; the feeding device comprises a feeding cylinder fixed at the top of a box body, a funnel is arranged in the box body, an electromagnetic valve is arranged at the bottom end of the funnel, and a culture dish is placed below the bottom end of the box body close to the funnel; the heating plates are embedded at the bottom side of the inside of the box body, and temperature sensors are symmetrically fixed at the two sides of the inside of the box body and close to the lower part of the funnel; the rotating rod is rotatably arranged in the middle of the top end in the box body, and a plurality of stirring rods are arranged on two sides of the rotating rod. However, in the prior art, nutrient solution needs to be added in the culture dish culture process, and the nutrient solution is synthesized by adopting multiple formulas, so that stirring is required to be implemented, but in the stirring mode in the prior art, a motor is utilized to drive a rotating rod to enable an external stirring rod to stir, a funnel structure is adopted at the inner side of the box body to conveniently discharge, precipitation is easily caused in the inner side of the box body, and the structure enables the stirrer to be difficult to stir the precipitate at the bottom of the box body, so that the stirring quality of the nutrient solution is influenced.

Disclosure of Invention

In view of the problems mentioned in the background art, it is an object of the present utility model to provide a stem cell incubator, which solves the problems mentioned in the background art above.

The technical aim of the utility model is realized by the following technical scheme:

the utility model provides a stem cell artificial containers, includes casing and shell door, the front of casing is equipped with the shell door, the front of shell door is equipped with control module, the inboard of casing is equipped with first rabbling mechanism, first rabbling mechanism's outside is equipped with second rabbling mechanism, the front inboard of casing is equipped with the constant head tank, the inboard of constant head tank is equipped with the hot plate, the upper end of hot plate is equipped with the culture dish, the inboard of casing is equipped with temperature sensor.

Further, as a preferable technical scheme, the front face of the shell door is provided with an observation window.

Further, as an optimal technical scheme, the left side and the right side of the lower end of the shell are symmetrically and fixedly provided with the support posts, and the lower ends of the support posts are provided with the mounting plates.

Further, as a preferable technical scheme, handles are symmetrically and fixedly arranged at the upper end of the culture dish.

Further, as the preferable technical scheme, the first stirring mechanism comprises a double-shaft motor, the double-shaft motor is fixedly arranged on the inner side of a shell, a first gear is fixedly arranged on the right output shaft of the double-shaft motor, a stirring cylinder is rotationally connected on the inner side of the shell, a toothed ring is fixedly arranged on the outer side of the stirring cylinder, the first gear is connected with the toothed ring Wei Niege, a material opening is formed in the upper end of the stirring cylinder, and the second stirring mechanism is arranged on the left output end of the double-shaft motor.

Further, as a preferable technical scheme, the inner side of the shell is fixedly provided with a mounting seat, and the double-shaft motor is fixedly arranged at the upper end of the mounting seat through a screw.

Further, as the preferable technical scheme, the second stirring mechanism comprises a second gear, the second gear is fixedly arranged at the left output end of the double-shaft motor, a stirrer is arranged at the inner side of the stirring cylinder, a third gear is fixedly arranged at the stirring shaft end of the stirrer, penetrating through the left side wall of the shell, and the outer sides of the second gear and the third gear are connected with the same toothed belt in a meshed mode.

Further, as a preferable technical scheme, a protective shell is fixedly arranged on the left side of the shell.

In summary, the utility model has the following advantages:

in the stirring process of the nutrient solution, firstly, the nutrient solution raw material is added into the stirring barrel through the material opening, then the control module controls and starts the double-shaft motor, the stirring barrel can rotate at the inner side of the shell by utilizing the first gear engagement transmission toothed ring at the right output end of the double-shaft motor, the internal nutrient solution is convenient to stir, bottom precipitation is not easy to be caused, meanwhile, on the basis of rotation of the right output shaft of the double-shaft motor, the left output shaft synchronously operates, so that the second gear on the left output shaft of the double-shaft motor utilizes the third gear of the toothed belt engagement transmission stirrer, the stirring barrel can be conveniently driven to rotate at the inner side of the stirring barrel, the nutrient solution is further mixed and stirred, precipitation is not easy to be caused, and the stirring quality of the nutrient solution can be greatly improved.

Drawings

FIG. 1 is a schematic diagram of the structure of the present utility model;

FIG. 2 is a schematic view of the internal structure of the housing of the present utility model;

fig. 3 is a schematic structural view of a second stirring mechanism of the present utility model.

Reference numerals: 1. the shell, 2, the shell door, 3, the observation window, 4, the control module, 5, the protecting crust, 6, the pillar, 7, the mounting disc, 8, temperature sensor, 9, the constant head tank, 10, the culture dish, 11, the hot plate, 12, the handle, 13, first rabbling mechanism, 131, churn, 132, the ring gear, 133, first gear, 134, biax motor, 14, the feed inlet, 15, second rabbling mechanism, 151, second gear, 152, toothed belt, 153, third gear, 154, agitator, 16, mount pad.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

Example 1

Referring to fig. 1-3, the stem cell incubator according to the present embodiment includes a housing 1 and a housing door 2, wherein the housing door 2 is provided on the front side of the housing 1, a control module 4 is provided on the front side of the housing door 2, a first stirring mechanism 13 is provided on the inner side of the housing 1, a second stirring mechanism 15 is provided on the outer side of the first stirring mechanism 13, a positioning groove 9 is provided on the inner side of the front side of the housing 1, a heating plate 11 is provided on the inner side of the positioning groove 9, a culture dish 10 is provided on the upper end of the heating plate 11, and a temperature sensor 8 is provided on the inner side of the housing 1; the front of the shell door 2 is provided with the observation window 3, and the observation of the culture dish 10 can be conveniently carried out by additionally arranging the observation window 3 on the front of the shell door 2; the temperature sensor 8 can monitor the temperature in the shell 1 and transmit signals to the control module 4, and the control module 4 controls the heating plate 11 to heat and preserve heat of the culture dish 10, so that stem cells are conveniently cultured; the left side and the right side of the lower end of the shell 1 are symmetrically and fixedly provided with the support posts 6, the lower end of the support posts 6 is provided with the mounting plate 7, and the installation of equipment can be facilitated by additionally arranging the support posts 6 at the lower end of the shell 1 and matching with the mounting plate 7 at the lower end of the support posts 6; the upper end of the mounting plate 7 is also provided with mounting holes at equal angles, so that the mounting plate can be conveniently mounted and fixed; the upper end of the culture dish 10 is symmetrically and fixedly provided with the handles 12, and the culture dish 10 can be conveniently taken out from the positioning groove 9 by additionally arranging the handles 12 at the upper end of the culture dish 10; the handle 12 is also provided with an anti-slip rubber sleeve which can increase friction and prevent slipping without grinding hands.

Example 2

Referring to fig. 2, in order to achieve the purpose of stirring the nutrient solution conveniently based on embodiment 1, in this embodiment, the first stirring mechanism 13 is innovatively designed, specifically, the first stirring mechanism 13 includes a dual-shaft motor 134, the dual-shaft motor 134 is fixedly installed inside the housing 1, a first gear 133 is fixedly installed on a right output shaft of the dual-shaft motor 134, a stirring cylinder 131 is rotatably connected to the inside of the housing 1, a toothed ring 132 is fixedly installed on the outside of the stirring cylinder 131, the first gear 133 is connected with the toothed ring 132 Wei Niege, a feed port 14 is provided at the upper end of the stirring cylinder 131, and the second stirring mechanism 15 is provided at the left output end of the dual-shaft motor 134, and by adding the first stirring mechanism 13 inside the housing 1, the first gear 133 at the right output end of the dual-shaft motor 134 is meshed with the transmission toothed ring 132, so that the stirring cylinder 131 can rotate inside the housing 1, thereby stirring the internal nutrient solution conveniently; the inner wall of the stirring barrel 131 is also provided with a stirring step, so that the stirring barrel can be rotated conveniently to drive the nutrient solution to be stirred and mixed; the material port 14 is also provided with a valve, so that liquid draining or nutrient solution injection can be conveniently performed.

Referring to fig. 2, in order to achieve the purpose of facilitating the installation of the dual-axis motor 134, the inner side of the housing 1 of the embodiment is fixedly provided with the installation seat 16, the dual-axis motor 134 is fixedly installed at the upper end of the installation seat 16 through screws, and the installation of the dual-axis motor 134 can be facilitated by adding the installation seat 16 on the inner side of the housing 1; two triangular reinforcing blocks are symmetrically arranged at the lower end of the mounting seat 16, so that the stability of the mounting seat 16 can be ensured.

Example 3

Referring to fig. 2-3, in this embodiment, based on embodiment 2, in order to achieve the purpose of improving the stirring efficiency, the second stirring mechanism 15 is innovatively designed, specifically, the second stirring mechanism 15 includes a second gear 151, the second gear 151 is fixedly installed at the left output end of the dual-shaft motor 134, a stirrer 154 is provided at the inner side of the stirring barrel 131, a third gear 153 is fixedly installed at the stirring shaft end of the stirrer 154 penetrating through the left side wall of the casing 1, the same toothed belt 152 is engaged with the outer sides of the second gear 151 and the third gear 153, and by adding the second stirring mechanism 15 on the basis of the first stirring mechanism 13, the right output shaft of the dual-shaft motor 134 rotates, and simultaneously, the left output shaft synchronously operates so that the second gear 151 on the left output shaft of the dual-shaft motor 134 engages with the third gear 153 of the transmission stirrer 154 by using the toothed belt 152, thereby conveniently driving the stirrer 154 to rotate at the inner side of the stirring barrel 131 to mix and stir the nutrient solution; the shaft portions of the stirrer 154 are rotatably connected to the stirring cylinder 131, so that stirring can be performed conveniently.

Referring to fig. 1, in order to achieve the purpose of conveniently protecting the toothed belt 152, the second gear 151 and the third gear 153, a protecting shell 5 is fixedly installed on the left side of the housing 1 in this embodiment, and the toothed belt 152, the second gear 151 and the third gear 153 can be protected by adding the protecting shell 5 on the left side of the housing 1; the left side of the protective shell 5 is also provided with an access door through screws, so that the stirrer 154 can be conveniently maintained and overhauled.

The use principle and the advantages are that: when the dry cell culture dish 10 is used, the positioning groove 9 in the shell 1 is arranged, then the shell door 2 is closed, nutrient solution needs to be stirred before nutrient solution is added, in the process of stirring the nutrient solution, firstly, nutrient solution raw materials are added into the stirring barrel 131 through the feed port 14, then the control module 4 is used for controlling and starting the double-shaft motor 134, the first gear 133 at the right side output end of the double-shaft motor 134 is meshed with the transmission toothed ring 132, the stirring barrel 131 can rotate inside the shell 1, stirring of internal nutrient solution is facilitated, bottom precipitation is not easy to cause, meanwhile, on the basis of rotation of the right side output shaft of the double-shaft motor 134, the second gear 151 on the left side output shaft of the double-shaft motor 134 is synchronously operated, the third gear 153 of the transmission stirrer 154 is meshed with the toothed belt 152, so that the stirrer 154 can be conveniently driven to rotate inside the stirring barrel 131, the nutrient solution is further mixed and stirred, the temperature inside the shell 1 can be monitored through the temperature sensor 8 at the inner side of the shell 1, and signals are transmitted to the control module 4, and the control module 4 is used for controlling the dish 10 to heat the cell culture dish, so that the cell culture dish 10 is heated and the cell culture plate is conveniently and kept warm.

Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.

Claims

1. A stem cell incubator, characterized in that: including casing (1) and shell door (2), the front of casing (1) is equipped with shell door (2), the front of shell door (2) is equipped with control module (4), the inboard of casing (1) is equipped with first rabbling mechanism (13), the outside of first rabbling mechanism (13) is equipped with second rabbling mechanism (15), the front inboard of casing (1) is equipped with constant head tank (9), the inboard of constant head tank (9) is equipped with hot plate (11), the upper end of hot plate (11) is equipped with culture dish (10), the inboard of casing (1) is equipped with temperature sensor (8).

2. A stem cell incubator as set forth in claim 1, wherein: an observation window (3) is arranged on the front face of the shell door (2).

3. A stem cell incubator as set forth in claim 1, wherein: the left side and the right side of the lower end of the shell (1) are symmetrically and fixedly provided with support posts (6), and the lower end of the support posts (6) is provided with a mounting plate (7).

4. A stem cell incubator as set forth in claim 1, wherein: handles (12) are symmetrically and fixedly arranged at the upper end of the culture dish (10).

5. A stem cell incubator as set forth in claim 1, wherein: the first stirring mechanism (13) comprises a double-shaft motor (134), the double-shaft motor (134) is fixedly arranged on the inner side of a shell (1), a first gear (133) is fixedly arranged on a right-side output shaft of the double-shaft motor (134), a stirring cylinder (131) is rotatably connected on the inner side of the shell (1), a toothed ring (132) is fixedly arranged on the outer side of the stirring cylinder (131), the first gear (133) is meshed with the toothed ring (132), a material inlet (14) is formed in the upper end of the stirring cylinder (131), and a second stirring mechanism (15) is arranged at the left-side output end part of the double-shaft motor (134).

6. A stem cell incubator as set forth in claim 5, wherein: the inner side of the shell (1) is fixedly provided with a mounting seat (16), and the double-shaft motor (134) is fixedly arranged at the upper end of the mounting seat (16) through screws.

7. A stem cell incubator as set forth in claim 5, wherein: the second stirring mechanism (15) comprises a second gear (151), the second gear (151) is fixedly arranged at the left output end of the double-shaft motor (134), a stirrer (154) is arranged on the inner side of the stirring barrel (131), a third gear (153) is fixedly arranged at the stirring shaft end of the stirrer (154) penetrating through the left side wall of the shell (1), and the same toothed belt (152) is connected with the outer sides of the second gear (151) and the third gear (153) in a meshed mode.

8. A stem cell incubator as set forth in claim 1, wherein: the left side of the shell (1) is fixedly provided with a protective shell (5).