CN219574019U - Titration device for drug research and development analysis - Google Patents

Titration device for drug research and development analysis Download PDF

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Publication number
CN219574019U
CN219574019U CN202222995064.2U CN202222995064U CN219574019U CN 219574019 U CN219574019 U CN 219574019U CN 202222995064 U CN202222995064 U CN 202222995064U CN 219574019 U CN219574019 U CN 219574019U
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China
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fixedly arranged
connecting rod
plate
bottom plate
fixed
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CN202222995064.2U
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Chinese (zh)
Inventor
钱勇
鲍杰华
孙福全
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Nanjing Guoxing Biotechnology Research Institute Co ltd
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Nanjing Guoxing Biotechnology Research Institute Co ltd
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/20Reduction of greenhouse gas [GHG] emissions in agriculture, e.g. CO2
    • Y02P60/21Dinitrogen oxide [N2O], e.g. using aquaponics, hydroponics or efficiency measures

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Abstract

The utility model relates to a titration device for drug research, development and analysis, which comprises a bottom plate, wherein a rotating motor is fixedly arranged in the bottom plate, an active deflector rod is welded at the tail end of an output shaft of the rotating motor, a fixed connecting rod is fixedly arranged on the surface of the active deflector rod, a limiting hole is fixedly arranged in the fixed connecting rod, a connecting rod is movably arranged in the limiting hole, a baffle is fixedly arranged at the tail end of the connecting rod, a spring is fixedly arranged on the side wall of the baffle and the limiting hole, a sheave is meshed with the active deflector rod, a rotating shaft is movably arranged in the bottom plate at the center of the sheave, and a turntable is fixedly arranged on the surface of the rotating shaft. According to the utility model, through the mutual matching of the driving plate and the grooved pulley, the rotary motion of the rotary motor is changed into the intermittent motion of the grooved pulley, so that the rotary table above the rotary motor can perform the intermittent motion, different reagent culture dishes can be conveniently titrated, the situation that the reagent culture dishes are frequently replaced in the later period is reduced, and the product research and development efficiency is improved. Is more practical and is suitable for wide popularization and use.

Description

Titration device for drug research and development analysis
Technical Field
The utility model belongs to the technical field of medicine research and development, and particularly relates to a titration device for medicine research and development analysis.
Background
The titration is to drop standard solution with known accurate concentration into the measured solution or drop the measured solution into the standard solution until the added standard solution quantitatively reacts with the measured substance according to the stoichiometric relation, then measure the consumed volume of the standard solution, and calculate the content of the measured substance according to the concentration of the standard solution and the consumed volume.
The utility model discloses an analysis titration apparatus for medicine research and development through retrieving CN 214750068U, including unable adjustment base, the regulating plate is installed to unable adjustment base's upper end, the adjustment tank has been seted up in the middle of unable adjustment base's the upper end, unable adjustment base's left end is connected with the bracing piece, unable adjustment base's right-hand member is connected with first motor. The gear drives the toothed bar to move downwards, the toothed bar drives the burette to move downwards until the lower end of the burette is close to the upper end of the analysis bottle, the toothed bar can move stably through the cooperation of the positioning sleeve and the second sliding bar, chemical medicines are prevented from flowing out during titration, the screw rod controls the adjusting block and the adjusting plate to move, the adjusting plate drives the fixing sleeve and the analysis bottle to move, the analysis bottle is moved to the lower end of the corresponding burette, and the air cylinder pushes the fixing block and the analysis bottle to move slowly back and forth during titration, so that the chemical medicines in the analysis bottle slightly shake, the mixing of the chemical medicines is accelerated, and different chemical medicine titration is facilitated.
In practical use, when the titration analysis and detection are carried out on the medicines, the medicines are required to be dripped on the surfaces of different medicines to observe the reaction, and the device can only titrate one medicine each time, so that the efficiency of test personnel is low when the detection is carried out, and the research and development process of the medicines is influenced.
The present utility model has been made in view of this.
Disclosure of Invention
In order to solve the technical problems, the utility model adopts the basic conception of the technical scheme that:
the utility model provides a titration apparatus for medicine research and development analysis, includes the bottom plate, the inside fixed rotating electrical machines that is provided with of bottom plate, the terminal welding of rotating electrical machines output shaft is provided with initiative driver plate, initiative driver plate fixed surface is provided with fixed connection pole, spacing hole has been seted up to fixed connection pole inside fixed, spacing hole inside activity is provided with the connecting rod, the terminal fixed baffle that is provided with of connecting rod, baffle and spacing hole lateral wall are fixed and are provided with the spring, initiative driver plate surface engagement is provided with the sheave, the sheave center is provided with the pivot activity and sets up inside the bottom plate, pivot fixed surface is provided with the carousel, carousel fixed surface is provided with a plurality of sleeve.
As a further improvement of the technical scheme, the side supporting plate is fixedly arranged on the side wall of the bottom plate, a sliding groove is formed in the center of the side supporting plate, a screw rod shaft is fixedly arranged on the side wall of the sliding groove, and the tail end of the screw rod shaft is fixedly connected with an output shaft of the lifting motor.
As a further improvement of the technical scheme, the surface of the screw rod shaft is provided with a lifting plate in a meshed mode, an injection shell is fixedly arranged at the center of the lifting plate, and an injection push rod is movably arranged in the injection shell.
As a further improvement of the technical scheme, three positioning bolts are arranged on the surface of each sleeve in a threaded engagement manner, and reagent culture dishes are placed in the central positions of the three positioning bolts.
As a further improvement of the above technical solution, the end of the injection housing is aligned with the center of the reagent culture dish.
As a further improvement of the technical scheme, the upper surface of the tail end of the connecting rod is slidably provided with a roller, and the roller is matched with a groove formed in the surface of the grooved pulley.
Compared with the prior art, the utility model has the following beneficial effects:
according to the utility model, through the mutual matching of the driving plate and the grooved pulley, the rotary motion of the rotary motor is changed into the intermittent motion of the grooved pulley, so that the rotary table above the rotary motor can perform the intermittent motion, different reagent culture dishes can be conveniently titrated, the situation that the reagent culture dishes are frequently replaced in the later period is reduced, and the product research and development efficiency is improved.
The following describes the embodiments of the present utility model in further detail with reference to the accompanying drawings.
Drawings
In the drawings:
FIG. 1 is a schematic three-dimensional structure of a titration apparatus for drug development and analysis;
FIG. 2 is a schematic diagram of a drive mechanism inside a bottom plate of a titration apparatus for drug development and analysis;
FIG. 3 is a side view of a titration apparatus for drug development analysis;
fig. 4 is a cross-sectional view of a connecting rod of a titration apparatus for drug development and analysis.
In the figure: 1. a bottom plate; 2. a side support plate; 3. a lifting motor; 4. a chute; 5. a lifting plate; 6. an injection push rod; 7. an injection housing; 8. a turntable; 9. a sleeve; 10. positioning bolts; 11. a reagent culture dish; 12. a rotating shaft; 13. a sheave; 14. an active dial; 15. fixing the connecting rod; 16. a connecting rod; 17. a roller; 18. a rotating electric machine; 19. a screw shaft; 20. a limiting hole; 21. a spring; 22. and a baffle.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present utility model more apparent, the technical solutions in the embodiments will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model, and the following embodiments are used to illustrate the present utility model.
Example 1:
as shown in fig. 1 to 4, a titration apparatus for drug development and analysis comprises a bottom plate 1, a rotating motor 18 is fixedly arranged in the bottom plate 1, an active driving plate 14 is welded and arranged at the tail end of an output shaft of the rotating motor 18, a fixed connecting rod 15 is fixedly arranged on the surface of the active driving plate 14, a limiting hole 20 is fixedly arranged in the fixed connecting rod 15, a connecting rod 16 is movably arranged in the limiting hole 20, a baffle 22 is fixedly arranged at the tail end of the connecting rod 16, a spring 21 is fixedly arranged on the side wall of the baffle 22 and the limiting hole 20, a grooved pulley 13 is meshed with the surface of the active driving plate 14, a rotating shaft 12 is movably arranged in the bottom plate 1 at the center of the grooved pulley 13, a rotary table 8 is fixedly arranged on the surface of the rotating shaft 12, and a plurality of sleeves 9 are fixedly arranged on the surface of the rotary table 8. By arranging the interaction of the driving dial 14 and the grooved pulley 13, the rotary motion of the rotary motor 18 is changed into intermittent motion of the grooved pulley 13, so that the turntable 8 above performs intermittent motion.
Example 2:
as the further optimization of the last step embodiment, a titration apparatus for medicine research, development and analysis comprises a base plate 1, a rotating motor 18 is fixedly arranged in the base plate 1, a driving plate 14 is welded and arranged at the tail end of an output shaft of the rotating motor 18, a fixed connecting rod 15 is fixedly arranged on the surface of the driving plate 14, a limiting hole 20 is fixedly arranged in the fixed connecting rod 15, a connecting rod 16 is movably arranged in the limiting hole 20, a baffle 22 is fixedly arranged at the tail end of the connecting rod 16, a spring 21 is fixedly arranged on the baffle 22 and the side wall of the limiting hole 20, a grooved pulley 13 is meshed with the surface of the driving plate 14, a rotating shaft 12 is movably arranged in the base plate 1 at the center of the grooved pulley 13, a rotary disc 8 is fixedly arranged on the surface of the rotating shaft 12, and a plurality of sleeves 9 are fixedly arranged on the surface of the rotary disc 8. The side support plate 2 is fixedly arranged on the side wall of the bottom plate 1, the sliding groove 4 is formed in the center of the side support plate 2, the screw rod shaft 19 is fixedly arranged on the side wall of the sliding groove 4, and the tail end of the screw rod shaft 19 is fixedly connected with the output shaft of the lifting motor 3. The rotation of the lifting motor 3 drives the screw shaft 19 of the device to start rotating.
Example 3:
as the further optimization of the last step embodiment, a titration apparatus for medicine research, development and analysis comprises a base plate 1, a rotating motor 18 is fixedly arranged in the base plate 1, a driving plate 14 is welded and arranged at the tail end of an output shaft of the rotating motor 18, a fixed connecting rod 15 is fixedly arranged on the surface of the driving plate 14, a limiting hole 20 is fixedly arranged in the fixed connecting rod 15, a connecting rod 16 is movably arranged in the limiting hole 20, a baffle 22 is fixedly arranged at the tail end of the connecting rod 16, a spring 21 is fixedly arranged on the baffle 22 and the side wall of the limiting hole 20, a grooved pulley 13 is meshed with the surface of the driving plate 14, a rotating shaft 12 is movably arranged in the base plate 1 at the center of the grooved pulley 13, a rotary disc 8 is fixedly arranged on the surface of the rotating shaft 12, and a plurality of sleeves 9 are fixedly arranged on the surface of the rotary disc 8. The surface of the screw rod shaft 19 is provided with a lifting plate 5 in a meshed manner, an injection shell 7 is fixedly arranged at the center of the lifting plate 5, and an injection push rod 6 is movably arranged in the injection shell 7. Through the mutual cooperation of injection push rod 6 and injection shell 7 that set up, reach titrating effect, can also conveniently control titrating content.
Example 4:
as the further optimization of the last step embodiment, a titration apparatus for medicine research, development and analysis comprises a base plate 1, a rotating motor 18 is fixedly arranged in the base plate 1, a driving plate 14 is welded and arranged at the tail end of an output shaft of the rotating motor 18, a fixed connecting rod 15 is fixedly arranged on the surface of the driving plate 14, a limiting hole 20 is fixedly arranged in the fixed connecting rod 15, a connecting rod 16 is movably arranged in the limiting hole 20, a baffle 22 is fixedly arranged at the tail end of the connecting rod 16, a spring 21 is fixedly arranged on the baffle 22 and the side wall of the limiting hole 20, a grooved pulley 13 is meshed with the surface of the driving plate 14, a rotating shaft 12 is movably arranged in the base plate 1 at the center of the grooved pulley 13, a rotary disc 8 is fixedly arranged on the surface of the rotating shaft 12, and a plurality of sleeves 9 are fixedly arranged on the surface of the rotary disc 8. Three positioning bolts 10 are arranged on the surface of each sleeve 9 in threaded engagement, and a reagent culture dish 11 is arranged in the center of each positioning bolt 10. The three positioning bolts 10 are matched with each other, so that the purpose of positioning the reagent culture dish 11 is achieved. The reagent can easily flow into the center of the reagent culture dish 11 by titration.
Example 5:
as the further optimization of the last step embodiment, a titration apparatus for medicine research, development and analysis comprises a base plate 1, a rotating motor 18 is fixedly arranged in the base plate 1, a driving plate 14 is welded and arranged at the tail end of an output shaft of the rotating motor 18, a fixed connecting rod 15 is fixedly arranged on the surface of the driving plate 14, a limiting hole 20 is fixedly arranged in the fixed connecting rod 15, a connecting rod 16 is movably arranged in the limiting hole 20, a baffle 22 is fixedly arranged at the tail end of the connecting rod 16, a spring 21 is fixedly arranged on the baffle 22 and the side wall of the limiting hole 20, a grooved pulley 13 is meshed with the surface of the driving plate 14, a rotating shaft 12 is movably arranged in the base plate 1 at the center of the grooved pulley 13, a rotary disc 8 is fixedly arranged on the surface of the rotating shaft 12, and a plurality of sleeves 9 are fixedly arranged on the surface of the rotary disc 8. The end of the injection housing 7 is aligned with the center of the reagent culture dish 11.
Example 6:
as the further optimization of the last step embodiment, a titration apparatus for medicine research, development and analysis comprises a base plate 1, a rotating motor 18 is fixedly arranged in the base plate 1, a driving plate 14 is welded and arranged at the tail end of an output shaft of the rotating motor 18, a fixed connecting rod 15 is fixedly arranged on the surface of the driving plate 14, a limiting hole 20 is fixedly arranged in the fixed connecting rod 15, a connecting rod 16 is movably arranged in the limiting hole 20, a baffle 22 is fixedly arranged at the tail end of the connecting rod 16, a spring 21 is fixedly arranged on the baffle 22 and the side wall of the limiting hole 20, a grooved pulley 13 is meshed with the surface of the driving plate 14, a rotating shaft 12 is movably arranged in the base plate 1 at the center of the grooved pulley 13, a rotary disc 8 is fixedly arranged on the surface of the rotating shaft 12, and a plurality of sleeves 9 are fixedly arranged on the surface of the rotary disc 8. The upper surface of the tail end of the connecting rod 16 is slidably provided with a roller 17, and the roller 17 is matched with a groove formed in the surface of the grooved pulley 13. The roller 17 can enter the groove formed on the surface of the grooved pulley 13, and the grooved pulley 13 can perform intermittent motion.
The implementation principle of the titration device for drug development and analysis in this embodiment is as follows: when a tester needs to perform titration operation, firstly, five reagent culture dishes 11 are put into different solutions, then, a rotating motor 18 of a device is started, at the moment, the rotating motor 18 drives a driving plate 14 to start rotating, a connecting rod 16 and a roller 17 on the driving plate 14 are contacted with grooves formed on the surface of a grooved pulley 13 to drive the grooved pulley 13 to start rotating, when the connecting rod 16 and the roller 17 are separated from the grooved pulley 13, the grooved pulley 13 is kept stationary, in the process, the connecting rod 16 is retracted, and is reset through a spring 21, when the grooved pulley 13 starts intermittent movement, at the moment, an injection shell 7 above the grooved pulley 13 titrates a reagent onto the surface of the reagent culture dish 11 in each interval, so that a titration experiment for medicine research and development is completed, and when the height is too high, the rotating motor 18 of the device is opened, at the moment, a screw shaft 19 is driven to rotate, and a lifting plate 5 meshed with the grooved pulley starts to move up and down, so that the lifting of the device is completed, and the condition that the reagent splashes due to the too high height in titration is reduced.

Claims (6)

1. The utility model provides a titration device for medicine research and development analysis, includes bottom plate (1), its characterized in that, inside fixed rotating electrical machines (18) that are provided with of bottom plate (1), rotating electrical machines (18) output shaft end welding is provided with initiative driver plate (14), initiative driver plate (14) fixed surface is provided with fixed connection pole (15), spacing hole (20) have been seted up to fixed connection pole (15) inside fixed, spacing hole (20) inside activity is provided with connecting rod (16), connecting rod (16) end fixed baffle (22) that are provided with, baffle (22) are provided with spring (21) with spacing hole (20) lateral wall fixed, initiative driver plate (14) surface engagement is provided with sheave (13), sheave (13) center is provided with pivot (12) activity setting inside bottom plate (1), pivot (12) fixed surface is provided with carousel (8), carousel (8) fixed surface is provided with a plurality of sleeve (9).
2. The titration apparatus for drug development and analysis according to claim 1, wherein a side support plate (2) is fixedly arranged on the side wall of the bottom plate (1), a sliding groove (4) is formed in the center of the side support plate (2), a screw shaft (19) is fixedly arranged on the side wall of the sliding groove (4), and the tail end of the screw shaft (19) is fixedly connected with an output shaft of a lifting motor (3).
3. The titration device for drug development and analysis according to claim 2, wherein the surface of the screw shaft (19) is provided with a lifting plate (5) in a meshed manner, an injection shell (7) is fixedly arranged at the center of the lifting plate (5), and an injection push rod (6) is movably arranged inside the injection shell (7).
4. Titration device for drug development and analysis according to claim 1, characterized in that three positioning bolts (10) are arranged on the surface of each sleeve (9) in threaded engagement, and a reagent culture dish (11) is arranged in the center of the three positioning bolts (10).
5. A titration device for drug development analysis according to claim 3, wherein the end of the injection housing (7) is aligned with the centre of the reagent culture dish (11).
6. The titration apparatus for drug development and analysis according to claim 1, wherein a roller (17) is slidably disposed on the upper surface of the distal end of the connecting rod (16), and the roller (17) is adapted to a groove formed in the surface of the sheave (13).
CN202222995064.2U 2022-11-10 2022-11-10 Titration device for drug research and development analysis Active CN219574019U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202222995064.2U CN219574019U (en) 2022-11-10 2022-11-10 Titration device for drug research and development analysis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202222995064.2U CN219574019U (en) 2022-11-10 2022-11-10 Titration device for drug research and development analysis

Publications (1)

Publication Number Publication Date
CN219574019U true CN219574019U (en) 2023-08-22

Family

ID=87652877

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202222995064.2U Active CN219574019U (en) 2022-11-10 2022-11-10 Titration device for drug research and development analysis

Country Status (1)

Country Link
CN (1) CN219574019U (en)

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