CN219539505U

CN219539505U - Bubble extraction device and analyzer

Info

Publication number: CN219539505U
Application number: CN202320861262.1U
Authority: CN
Inventors: 彭波南; 全骞; 侯碧波
Original assignee: Zhongyuan Huiji Biotechnology Co Ltd
Current assignee: Zhongyuan Huiji Biotechnology Co Ltd
Priority date: 2023-04-17
Filing date: 2023-04-17
Publication date: 2023-08-18
Anticipated expiration: 2033-04-17

Abstract

The utility model discloses a bubble extraction device, which is characterized in that a liquid inlet, a liquid outlet and a negative pressure air outlet are arranged in a bubble extraction cavity, wherein the liquid inlet is used for injecting liquid of bubbles to be extracted into the bubble extraction cavity, the liquid outlet is used for discharging liquid of which the bubble extraction is completed, the negative pressure air outlet is used for discharging gas in the bubble extraction cavity, and the negative pressure air outlet is arranged outside a region where the liquid is positioned so as to prevent the negative pressure air outlet from directly extracting liquid such as a reagent or a sample; through connect the negative pressure unit and take out the cavity to the bubble and take out negative pressure on the negative pressure gas vent, under the effect of negative pressure, the pressure that the tiny bubble that the suspension was in liquid received reduces, and the tiny bubble inflation, the buoyancy that the tiny bubble received after the inflation increases to discharge from liquid upper portion, thereby realize the effect that the bubble took out away, and can effectively improve efficiency. The bubble extraction device and the analyzer can realize the technical effect of extracting bubbles from a sample or a reagent.

Description

Bubble extraction device and analyzer

Technical Field

The utility model belongs to the technical field of in-vitro diagnosis, and particularly relates to a bubble extraction device and an analyzer.

Background

The analyzer is required to have a relatively high purity of the reagent, and not only a small impurity particle content but also as few fine bubbles as possible in the reagent are required. Of course, there is also a high requirement for control of the microbubble content for the sample, particularly after dilution or pretreatment.

In the conventional analyzers, a filter for filtering foreign particles is generally provided, but the filter for filtering foreign particles has a poor filtering effect on bubbles in a sample or a reagent. Some studies have proposed the use of a separate bubble filter to filter bubbles, injecting a sample or reagent into the front cavity of the bubble filter, allowing the sample or reagent to pass through the filter structure under natural conditions for the technical purpose of filtering micro bubbles. However, the conventional filtering method is still adopted for the conventional filtering result, and only the pore diameter of the filtering structure is different, so that the filtering effect on the micro bubbles is poor, and the filtering efficiency is also reduced due to the reduction of the filtering pore diameter.

Disclosure of Invention

In view of the above, an object of the present utility model is to provide a bubble extraction device and an analyzer that can extract bubbles from a sample or a reagent by floating up and discharging the bubbles in the sample or the reagent by negative pressure.

In order to achieve the above purpose, the present utility model provides the following technical solutions:

the utility model firstly provides a bubble extraction device which comprises a bubble extraction chamber, wherein a gas-liquid separation membrane is arranged in the bubble extraction chamber, the gas-liquid separation membrane divides the bubble extraction chamber into a negative pressure chamber and a liquid chamber, a liquid inlet and a liquid outlet are arranged in the liquid chamber, and a negative pressure exhaust port is arranged in the negative pressure chamber.

Further, the negative pressure chamber is located above the liquid chamber.

Further, the gas-liquid separation membrane is horizontally or obliquely arranged in the bubble extraction cavity.

Further, the axes of the liquid inlet and the liquid outlet are parallel to each other.

Further, the axes of the liquid inlet and the liquid outlet are intersected or spatially intersected.

Further, the axes of the liquid inlet and the liquid outlet are vertically intersected or spatially vertical.

Further, the caliber of the liquid inlet is larger than that of the liquid outlet.

The utility model also provides an analyzer comprising the bubble extraction device.

Further, the vacuum pump also comprises a negative pressure unit, and the negative pressure unit is connected with the negative pressure exhaust port.

Further, the device also comprises a liquid path driving system and a sample driving system, wherein the bubble extraction device shares the negative pressure unit with the liquid path driving system or the sample driving system.

The utility model has the beneficial effects that:

according to the bubble extraction device, the gas-liquid separation membrane is arranged in the bubble extraction chamber, so that the gas-liquid separation membrane can be utilized to separate the negative pressure chamber and the liquid chamber in the bubble extraction chamber, the liquid inlet and the liquid outlet are arranged in the liquid chamber, the liquid inlet is used for injecting the liquid of the bubbles to be extracted into the bubble extraction chamber, the liquid outlet is used for discharging the liquid of which the bubble extraction is completed, and the bubble extraction can be continuously carried out on the liquid such as a reagent or a sample; the negative pressure exhaust port is arranged in the negative pressure cavity, so that the negative pressure exhaust port is positioned outside the area (the liquid cavity) where the liquid is positioned, and the liquid is prevented from being extracted from the negative pressure exhaust port; under the negative pressure action of the negative pressure chamber, the pressure of the micro bubbles suspended in the liquid is reduced, the micro bubbles expand, the buoyancy of the expanded micro bubbles is increased, and the micro bubbles are discharged from the upper part of the liquid, so that the effect of pumping out the bubbles is realized; compared with the existing bubble filtering technology, the bubble extraction device is not limited by a filtering structure, so that tiny bubbles in liquid can be discharged, and the efficiency can be effectively improved.

Meanwhile, by controlling the flow of the liquid inlet and the liquid outlet, if the flow of the liquid inlet is slightly larger than the flow of the liquid outlet, certain extrusion effect of liquid on the gas-liquid separation membrane can be achieved, so that the gas pumping effect is improved.

Drawings

In order to make the objects, technical solutions and advantageous effects of the present utility model more clear, the present utility model provides the following drawings for description:

FIG. 1 is a schematic diagram of an embodiment of a bubble extraction apparatus according to the present utility model;

FIG. 2 is a schematic view of the structure of a gas-liquid separation membrane when it is horizontally arranged;

fig. 3 is a schematic structural view of the liquid inlet and the liquid outlet when the axes are vertical.

Reference numerals illustrate:

10-a bubble extraction device; 10 a-a negative pressure chamber; 10 b-a liquid chamber; 11-a liquid inlet; 12-a liquid outlet; 13-a negative pressure exhaust port; 14-gas-liquid separation membrane.

Detailed Description

The present utility model will be further described with reference to the accompanying drawings and specific examples, which are not intended to limit the utility model, so that those skilled in the art may better understand the utility model and practice it.

The analyzer of the present embodiment includes a bubble extraction device 10 and a negative pressure unit. As shown in fig. 1, the bubble extraction device 10 of the present embodiment includes a bubble extraction chamber, a gas-liquid separation membrane 14 is disposed in the bubble extraction chamber, the gas-liquid separation membrane 14 separates the bubble extraction chamber into a negative pressure chamber 10a and a liquid chamber 10b, a liquid inlet 11 for injecting liquid to be extracted from the bubble and a liquid outlet 12 for discharging the bubble after the bubble extraction are disposed in the liquid chamber 10b, and a negative pressure air outlet 13 is disposed in the negative pressure chamber 10 a. By providing the gas-liquid separation membrane 14 in the bubble extraction chamber, the gas-liquid separation membrane 14 allows the passage of gas but does not allow the passage of liquid, so that it is possible to ensure that the liquid such as a reagent or a sample is not extracted from the negative pressure gas outlet 13. In order to maintain continuous and stable negative pressure, a negative pressure unit is connected to the negative pressure exhaust port. Specifically, in the analyzer, one negative pressure unit may be provided for the bubble extraction device 10 alone, but the existing negative pressure unit in the analyzer may be shared. Specifically, the analyzer of this embodiment further includes a liquid path driving system and a sample driving system, and the bubble extraction device 10 shares the negative pressure unit with the liquid path driving system or the sample driving system, so that the negative pressure unit is not required to be separately set.

In the bubble extraction device 10 of this embodiment, by disposing the gas-liquid separation membrane 14 in the bubble extraction chamber, the gas-liquid separation membrane 14 can be utilized to separate the negative pressure chamber 10a and the liquid chamber 10b in the bubble extraction chamber, the liquid inlet 11 and the liquid outlet 12 are disposed in the liquid chamber 10b, the liquid inlet 11 is utilized to inject the liquid to be extracted from the bubble extraction chamber, the liquid outlet 12 is utilized to discharge the liquid from which the bubble extraction has been completed, and the bubble extraction can be continuously performed on the liquid such as the reagent or the sample, thereby improving the production efficiency. The negative pressure vent 13 is provided in the negative pressure chamber 10a, so that the negative pressure vent 13 is located outside the region where the liquid is located (liquid chamber), and the liquid is prevented from being drawn out from the negative pressure vent. Under the negative pressure action of the negative pressure chamber 10b, the pressure received by the micro-bubbles suspended in the liquid is reduced, the micro-bubbles expand, the buoyancy received by the expanded micro-bubbles is increased, the micro-bubbles are discharged from the upper part of the liquid, and the discharged gas enters the negative pressure chamber 10a through the gas-liquid separation membrane 14 and is discharged through the negative pressure exhaust port 13, so that the effect of bubble extraction is realized. Compared with the existing bubble filtering technology, the bubble extraction device 10 of the embodiment is not limited by the filtering structure, and can not only discharge micro bubbles in the liquid, but also effectively improve the efficiency.

Specifically, the gas-liquid separation membrane 14 may allow gas to pass through, but not liquid to pass through, so that a definite negative pressure chamber 10a and liquid chamber 10b may be formed in the bubble extraction chamber, and the positional relationship of the negative pressure chamber 10a and liquid chamber 10b is related according to the arrangement position and posture of the gas-liquid separation membrane 14 in the bubble extraction chamber. In the preferred embodiment of the present embodiment, the negative pressure chamber 10a is located above the liquid chamber 10b, so that the gas with a smaller density moves upward and directly passes from the liquid chamber 10b through the gas-liquid separation membrane 14 into the negative pressure chamber 10a, thereby improving the gas pumping effect. In order to locate the negative pressure chamber 10a above the liquid chamber 10b, the gas-liquid separation membrane 14 may be disposed horizontally or obliquely in the bubble extraction chamber, as shown in fig. 1-2.

In this embodiment, the axes of the liquid inlet 11 and the liquid outlet 12 are parallel to each other, i.e. the axes of the liquid inlet 11 and the liquid outlet 12 are not coaxial, so as to avoid that the liquid introduced from the liquid inlet 11 is directly discharged from the liquid outlet 12, so that the liquid can stay in the bubble extraction chamber for a longer time, so as to improve the bubble extraction effect, as shown in fig. 1-2. Of course, in other embodiments, the axes of the liquid inlet 11 and the liquid outlet 12 may be intersected or spatially intersected, and of course, the axes of the liquid inlet 11 and the liquid outlet 12 may be intersected or spatially perpendicular to each other, as shown in fig. 3, so that the liquid introduced from the liquid inlet 11 is avoided from being directly discharged from the liquid outlet 12 to some extent. In this embodiment, the liquid outlet 12 is disposed at the bottom of the liquid chamber 10b, the liquid inlet 11 is disposed at the top of the liquid chamber 10b, and the axes of the liquid outlet 12 and the liquid inlet 11 are not coaxial. In a preferred implementation manner of this embodiment, the caliber of the liquid inlet 11 may be set to be larger than the caliber of the liquid outlet 12, and the flow rates of the liquid inlet 11 and the liquid outlet 12 may be controlled, for example, the flow rate of the liquid inlet 11 is slightly larger than the flow rate of the liquid outlet 12, so that the liquid may have a certain extrusion effect on the gas-liquid separation membrane 14, so as to improve the gas pumping effect.

The above-described embodiments are merely preferred embodiments for fully explaining the present utility model, and the scope of the present utility model is not limited thereto. Equivalent substitutions and modifications will occur to those skilled in the art based on the present utility model, and are intended to be within the scope of the present utility model. The protection scope of the utility model is subject to the claims.

Claims

1. The utility model provides a bubble takes out and leaves device which characterized in that: the device comprises a bubble extraction chamber, wherein a gas-liquid separation membrane is arranged in the bubble extraction chamber, the gas-liquid separation membrane divides the bubble extraction chamber into a negative pressure chamber and a liquid chamber, a liquid inlet and a liquid outlet are arranged in the liquid chamber, and a negative pressure exhaust port is arranged in the negative pressure chamber;

the negative pressure cavity is located above the liquid cavity, the gas-liquid separation membrane is obliquely arranged in the bubble extraction cavity, the liquid inlet is located on one side of the gas-liquid separation membrane, which is higher, the liquid outlet is located on one side of the gas-liquid separation membrane, which is lower, and the caliber of the liquid inlet is larger than that of the liquid outlet.

2. The bubble extraction apparatus of claim 1, wherein: the axes of the liquid inlet and the liquid outlet are parallel to each other.

3. The bubble extraction apparatus of claim 1, wherein: the axes of the liquid inlet and the liquid outlet are intersected or spatially intersected.

4. The bubble extraction apparatus of claim 1, wherein: the axes of the liquid inlet and the liquid outlet are vertically intersected or are vertical in space.

5. An analyzer, characterized by: comprising a bubble extraction device according to any one of claims 1-4.

6. The analyzer of claim 5, wherein: the negative pressure unit is connected with the negative pressure exhaust port.

7. The analyzer of claim 6, wherein: the bubble extraction device and the liquid path driving system or the sample driving system share the negative pressure unit.