CN219524692U - Drawer type PCR tube cryopreservation box - Google Patents

Abstract

The utility model relates to a drawer type PCR tube freezing box, which comprises a shell, wherein the shell is a cube with the height of 50-55 mm, the bottom surface of 175-185 mm, the width of 95-100 mm and one side surface of the cube with an opening. The upper drawer frame and the lower drawer frame are arranged in the shell in a vertically stacked manner, and can be independently pulled out from the opening of the shell. The upper drawer frame and the lower drawer frame are respectively provided with PCR tube limiting holes which are arranged in an array manner and used for placing PCR tubes; a cold accumulation layer is arranged outside the limiting hole of the PCR tube, and a heat preservation layer is arranged outside the cold accumulation layer; the cold accumulation layer contains cold accumulation medium, and the heat preservation layer is filled with heat preservation medium. The size of the drawer-type PCR tube freezing box provided by the utility model is matched with that of a refrigerator storage rack commonly used in a laboratory, so that the PCR tube can be stably stored, and long-lasting low-temperature storage and operation conditions are provided for samples in the PCR tube, and the drawer-type PCR tube freezing box is particularly suitable for popularization and use in conventional clinical examination and scientific research laboratories.

Description

Drawer type PCR tube cryopreservation box

Technical Field

The utility model relates to the technical field of biochemical experiment tools, in particular to a drawer type PCR tube cryopreservation box.

Background

PCR (polymerase chain reaction) technology is often used in basic research, teaching and clinical trials in biology. The PCR technology is a molecular biological technology for amplifying specific DNA fragments, in the PCR experiment process, the PCR tubes are often required to be used for collecting experimental samples, and different reaction liquids are added into different groups of PCR tubes for gene detection, biological sample identification and the like. After the sample is collected by using the PCR tube, it is required to be placed in a storage device to facilitate the operation and use of the subsequent experiment. In addition, when the reagents in the PCR tube are required to be stored or subjected to experimental operations in a low temperature environment, the PCR plate is often placed in a refrigerator or above ice cubes to achieve a low temperature effect.

The conventional PCR tube storage device is mainly a 96-hole PCR tube rack box (31 mm in height; 125mm in bottom surface length and 88mm in width) suitable for a 0.2ml PCR tube. However, the existing PCR tube rack box generally has the defects that the box cover is easy to slip, the size is single, the box cover is not matched with a refrigerator storage rack commonly used in a laboratory, and the box cover does not have a low-temperature maintaining function.

Disclosure of Invention

In view of the problems existing in the background technology, the utility model provides a drawer type PCR tube cryopreservation box.

The drawer-type PCR tube cryopreservation box provided by the utility model comprises a shell, wherein the shell is a cube with the height of 50-55 mm, the bottom surface length of 175-185 mm, the bottom surface width of 95-100 mm and one side surface opening; wherein, upper drawer frame and lower drawer frame are located the inside of shell in a stack up and down, and upper drawer frame and lower drawer frame can independently be taken out from the opening of shell. Upper-layer PCR tube limiting holes arranged in an array manner are formed in the upper drawer frame; the upper drawer frame also comprises an upper cold accumulation layer arranged outside the limit hole of the upper PCR tube and an upper heat preservation coating arranged outside the upper cold accumulation layer; lower-layer PCR tube limiting holes arranged in an array manner are formed in the lower drawer frame; the lower drawer frame also comprises a lower cold accumulation layer arranged outside the limit hole of the lower PCR tube and a lower heat preservation coating arranged outside the lower cold accumulation layer; the upper cold accumulation layer and the lower cold accumulation layer contain cold accumulation media, and the upper heat preservation layer and the lower heat preservation layer are filled with heat preservation media.

For the prior art, the drawer type PCR tube cryopreservation box provided by the utility model has a double-layer drawer type design, the upper drawer frame and the lower drawer frame can be independently pulled out from the opening of the shell, and when the upper drawer frame and the lower drawer frame are positioned in the shell, the phenomena that the box cover of the existing PCR tube box is easy to slip, sample pollution is caused and even the PCR tube falls from the box are avoided. The shell of the drawer-type PCR tube freezing box provided by the utility model is 50-55 mm in height, 175-185 mm in bottom surface length and 95-100 mm in bottom surface width, and the size is matched with the layer height and the size of a refrigerator storage rack conventionally used in a laboratory at present, so that the storage space can be effectively utilized, and the refrigerator can be properly stored. More importantly, if the cold accumulation layer is arranged outside the limiting hole of the PCR tube, the heat preservation layer is arranged outside the cold accumulation layer, cold accumulation medium is contained in the cold accumulation layer, even if the drawer type PCR tube freezing box is taken out of the refrigerator, the cold accumulation layer and the heat preservation layer can provide low-temperature preservation conditions for samples in the PCR tube, and the heat preservation layer outside the cold accumulation layer can isolate the external environment and keep the low temperature of the cold accumulation layer for a long time. Therefore, the drawer-type PCR tube freezing box provided by the utility model has the characteristics of easiness in stable storage of the PCR tube, matching with a refrigerator storage rack commonly used in a laboratory, capability of providing durable low-temperature storage and operation conditions for the PCR tube and the like, and is suitable for popularization and use.

Further, an upper layer cold accumulation medium injection port is arranged at the top of the upper layer cold accumulation layer; the top of the lower cold accumulation layer is provided with a lower cold accumulation medium injection port. The cold accumulation medium injection ports are respectively arranged at the top parts of the upper cold accumulation layer and the lower cold accumulation layer, so that the cold accumulation medium in the upper cold accumulation layer and the lower cold accumulation layer can be replaced when necessary according to the use condition.

Further, the surface of the hole wall of the upper-layer PCR tube limiting hole facing the hole is provided with an upper-layer rough part; the hole wall of the lower PCR tube limiting hole faces the surface in the hole and is provided with a lower rough part. Preferably, the upper roughness and the lower roughness are respectively frosted surfaces. The rough part is arranged on the surface of the hole wall of the PCR tube limiting hole facing the inside of the hole, so that the friction force between the PCR tube placed in the rough part and the hole wall of the PCR tube limiting hole can be increased, and the PCR tube is more firmly placed in the drawer type PCR tube freezing box, so that the PCR tube is not easy to slip out or fall off and the like.

Preferably, the aperture and the height of the upper layer PCR tube limit hole and the lower layer PCR tube limit hole are suitable for the pipe diameter and the height of a 0.2ml PCR tube; the shell is a cube with the height of 58 mm, the bottom surface of 180 mm and the width of 98 mm. The heights of the upper drawer frame and the lower drawer frame are equal; 144 upper-layer PCR tube limiting holes are formed in the upper drawer frame; 144 lower PCR tube limiting holes are formed in the lower drawer frame. The drawer type PCR tube cryopreservation box designed according to the size can be specially suitable for the 0.2ml PCR tube commonly used in the laboratory at present.

Further, the upper drawer frame and the lower drawer frame are respectively provided with a drawer slide rail, the inner wall of the shell is provided with a slide groove, and the drawer slide rails are in sliding fit with the slide grooves; and at least one end of the sliding groove is provided with a locking mechanism for locking the upper drawer frame and the lower drawer. Through the arrangement of the drawer slide rail, the slide groove and the locking mechanism, the upper drawer frame and the lower drawer frame can be conveniently pulled out and pushed in from the shell, and the stability of the positions of the upper drawer frame and the lower drawer frame is ensured after the upper drawer frame and the lower drawer frame are pushed into the shell.

Drawings

FIG. 1 is a schematic view showing the structure of an upper drawer frame and a lower drawer frame of a drawer-type PCR-tube cryopreservation cassette according to a first embodiment of the present utility model when the upper drawer frame and the lower drawer frame are not drawn out from a housing;

FIG. 2 is a schematic view showing the structure of the drawer-type PCR-tube cryopreservation cassette according to the first embodiment of the present utility model when the upper drawer and the lower drawer are drawn out from the housing;

FIG. 3 is a schematic cross-sectional view of an upper drawer frame according to a first embodiment of the present utility model;

FIG. 4 is an enlarged schematic view of a limiting hole of an upper PCR tube according to a second embodiment of the present utility model;

fig. 5 is a top view of an upper drawer frame according to a third embodiment of the present utility model.

Detailed Description

Embodiments of the present utility model will be described in detail below. The following embodiments are only for more clearly illustrating the technical aspects of the present utility model, and thus are merely examples, and are not intended to limit the scope of the present utility model. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this utility model belongs. Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment may be included in at least one embodiment of the utility model. The appearances of such phrases in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. Those skilled in the art will explicitly and implicitly understand that the embodiments described herein may be combined with other embodiments.

The first embodiment of the utility model provides a drawer type PCR tube cryopreservation box, as shown in fig. 1 and 2, which comprises a shell 1, wherein the shell 1 is a cube with the height of 50-55 mm, the bottom surface of 175-185 mm, the width of 95-100 mm and one side surface of the cube with an opening. The inside of the housing 1 is divided into two layers, an upper drawer frame 21 and a lower drawer frame 31 are provided in the inside of the housing 1 in a vertically stacked manner, and the upper drawer frame 21 and the lower drawer frame 31 are independently drawn out from the opening of the housing 1. Fig. 1 is a schematic view of the upper drawer frame 21 and the lower drawer frame 31 not being drawn out from the opening of the housing 1;

fig. 2 is a schematic view of the upper drawer frame 21 and the lower drawer frame 31 drawn out from the opening of the housing 1. As can also be seen from fig. 2, in order to facilitate the sliding of the upper and lower drawer frames in the housing, this embodiment provides an upper drawer slide 27 on the side of the upper drawer frame 21, a lower drawer slide 37 on the side of the lower drawer frame 31, and a sliding groove (not shown in the figures) on the inner wall of the corresponding position of the housing 1, said drawer slide being in sliding engagement with said sliding groove. Furthermore, the locking mechanism for locking the upper drawer frame 21 and the lower drawer frame 31 is provided at least one end of the slide groove.

FIG. 3 is a schematic cross-sectional view of an upper drawer frame or a lower drawer frame (the structure of the lower drawer frame is the same as that of the upper drawer frame), and as shown in FIG. 3, upper-layer PCR tube limiting holes 22 arranged in an array are arranged in the upper drawer frame; the upper drawer frame 21 further comprises an upper layer cold accumulation layer 23 arranged outside the upper layer PCR tube limiting hole 22 and an upper layer heat preservation layer 24 arranged outside the upper layer cold accumulation layer 23, wherein cold accumulation media are contained in the upper layer cold accumulation layer 23, an upper layer cold accumulation medium injection opening 25 is arranged at the top of the upper layer cold accumulation layer 23, cold accumulation media can be injected into the upper layer cold accumulation layer 23 through the upper layer cold accumulation medium injection opening 25, and the upper layer heat preservation layer 24 is filled with heat preservation media.

Similarly, lower-layer PCR tube limiting holes which are arranged in an array manner are also formed in the lower drawer frame; the lower drawer frame also comprises a lower cold accumulation layer arranged outside the limit hole of the lower PCR tube and a lower heat preservation layer arranged outside the lower cold accumulation layer, wherein heat preservation medium is filled in the lower heat preservation layer, and a lower cold accumulation medium injection opening is arranged at the top of the lower cold accumulation layer.

As can be seen from the above description, the drawer-type PCR tube cryopreservation box provided in this embodiment has a double-layer drawer design, and the upper drawer frame and the lower drawer frame can be independently pulled out from the opening of the housing, so as to perform the placement and removal operations of the PCR tube. When the upper drawer frame and the lower drawer frame are pushed into the outer shell, the upper drawer frame and the lower drawer frame are positioned inside the outer shell, the PCR tube and samples in the PCR tube are well protected, and the phenomena that the box cover possibly exists in the existing PCR tube box is easy to slip, sample pollution is caused, and even the PCR tube falls from the box are avoided. The upper drawer frame and the lower drawer frame in the PCR tube freezing box provided by the embodiment can be conveniently pulled out and pushed in from the shell, and the stability of the positions of the upper drawer frame and the lower drawer frame is ensured after the upper drawer frame and the lower drawer frame are pushed into the shell, so that the stability of the PCR tubes placed in the upper drawer frame and the lower drawer frame is ensured.

In addition, the cold accumulation layer is arranged outside the limiting hole of the PCR tube, the heat preservation layer is arranged outside the cold accumulation layer, cold accumulation medium is contained in the cold accumulation layer, and the heat preservation layer is filled with the heat preservation medium. Even if the drawer-type PCR tube freezing box is taken out of the refrigerator, a low-temperature environment can be provided for a sample in the PCR tube through the cold accumulation layer, the heat preservation layer outside the cold accumulation layer can isolate the external environment, and the long-time low temperature of the cold accumulation layer can be kept. In the present embodiment, the cold storage medium inlets are provided at the top of the upper cold storage layer and the lower cold storage layer, respectively, so that the cold storage medium in the upper and lower cold storage layers can be replaced as necessary according to the use condition.

In addition, the shell of the drawer-type PCR tube freezing box of the embodiment is 50-55 mm in height, 175-185 mm in bottom surface length and 95-100 mm in bottom surface width, and the size is matched with the layer height and the size of a refrigerator storage rack conventionally used in a laboratory at present, so that the drawer-type PCR tube freezing box can be stored in a refrigerator properly.

Therefore, the drawer-type PCR tube cryopreservation box provided by the embodiment has the characteristics of being easy for stable storage of the PCR tube, matching with a refrigerator storage rack commonly used in a laboratory, being capable of providing durable low-temperature storage and operation environment for the PCR tube and the like, and is suitable for popularization and use in the current laboratory and clinical examination work.

The second embodiment of the utility model is an improvement of the first embodiment, and specifically, the second embodiment is an improvement of the limit hole of the PCR tube on the basis of the drawer-type PCR tube cryopreservation box provided by the first embodiment. Fig. 4 is an enlarged view showing the wall structure of the upper layer PCR tube limiting hole 22. As shown in fig. 4, the surface of the hole wall of the upper layer PCR tube limiting hole 22 facing the hole interior is provided with an upper layer roughness 26; the upper rough portion 26 is preferably located from the middle to the lower portion of the wall of the upper PCR tube limiting hole 22, and the upper rough portion 26 is a frosted surface.

Similarly, the surface of the hole wall of the lower-layer PCR tube limiting hole facing the hole is also provided with a lower-layer rough part, the lower-layer rough part is preferably positioned from the middle part to the lower part of the hole wall of the lower-layer PCR tube limiting hole, and the lower-layer rough part is a frosted surface.

In the embodiment, the rough part is arranged on the surface of the hole wall of the PCR tube limiting hole facing the inside of the hole, so that the friction force between the PCR tube and the hole wall of the PCR tube limiting hole can be increased, and the PCR tube is more firmly placed in the drawer type PCR tube freezing box, so that the PCR tube is not easy to slip or fall off and the like.

The third embodiment of the utility model is a further improvement of the first and second embodiments, and in particular provides a drawer-type PCR tube freezing box which is more matched with conventional laboratory equipment in terms of the overall size of the freezing box and the size setting of a limiting hole of a PCR tube and is more suitable for practical application. In the drawer-type PCR tube cryopreservation box provided by the embodiment, the height of the shell is 58 mm, the bottom surface is 180 mm long and the width is 98 mm; the heights of the upper drawer frame and the lower drawer frame are equal; the aperture and the height of the upper layer PCR tube limiting hole and the lower layer PCR tube limiting hole are suitable for the pipe diameter and the height of a 0.2ml PCR tube. According to the size, 144 upper-layer PCR tube limiting holes are formed in the upper drawer frame in the drawer type PCR tube freezing box of the embodiment; 144 lower PCR tube limiting holes are also arranged in the lower drawer frame. Fig. 5 is a top view of the upper drawer frame of the present embodiment, and as shown in fig. 5, the upper PCR tube limiting holes 22 in the upper drawer frame are arranged in an 8×18 array, and there are 144 total. Similarly, the limiting holes of the lower PCR tubes in the lower drawer frame are also arranged in an 8×18 array, and the number of the limiting holes is 144. In this embodiment, the drawer type PCR tube freezing box with the above-mentioned size design can be specially adapted for a 0.2ml PCR tube commonly used in a laboratory.

Variations and modifications to the above would be obvious to one of ordinary skill in the art in light of the foregoing disclosure and teachings. Therefore, the utility model is not limited to the specific embodiments disclosed and described above, but some modifications and changes of the utility model should be also included in the scope of the claims of the utility model. In addition, although specific terms are used in the present specification, these terms are for convenience of description only and do not limit the present utility model in any way.

Claims (10)

1. A drawer type PCR tube freezes deposits box, its characterized in that: comprises a shell, wherein the shell is a cube with the height of 50-55 mm, the bottom surface length of 175-185 mm, the bottom surface width of 95-100 mm and an opening at the side surface;

the upper drawer frame and the lower drawer frame are arranged in the shell in a vertically stacked manner, and can be independently pulled out from the opening of the shell;

upper-layer PCR tube limiting holes arranged in an array manner are formed in the upper drawer frame; the upper drawer frame also comprises an upper cold accumulation layer arranged outside the limit hole of the upper PCR tube and an upper heat preservation layer arranged outside the upper cold accumulation layer;

the lower drawer frame is internally provided with lower-layer PCR tube limiting holes which are arrayed; the lower drawer frame also comprises a lower cold accumulation layer arranged outside the limit hole of the lower PCR tube and a lower heat preservation layer arranged outside the lower cold accumulation layer;

the upper cold accumulation layer and the lower cold accumulation layer contain cold accumulation media, and the upper heat preservation layer and the lower heat preservation layer are filled with heat preservation media.

2. The drawer-type PCR tube cryopreservation box as claimed in claim 1, wherein an upper cold storage medium injection port is arranged at the top of the upper cold storage layer; the top of the lower cold accumulation layer is provided with a lower cold accumulation medium injection port.

3. The drawer-type PCR tube cryopreservation box according to claim 1, wherein the surface of the hole wall of the upper-layer PCR tube limiting hole facing the hole is provided with an upper-layer rough part; the hole wall of the lower PCR tube limiting hole faces the surface in the hole and is provided with a lower rough part.

4. The drawer-type PCR tube cryopreservation cassette as claimed in claim 3, wherein the upper roughness and the lower roughness are frosted surfaces.

5. The drawer-type PCR tube cryopreservation box as claimed in claim 1, wherein the aperture and the height of the upper layer PCR tube limit hole and the lower layer PCR tube limit hole are suitable for the tube diameter and the height of the 0.2ml PCR tube.

6. The drawer-type PCR tube cryopreservation cartridge of claim 1, wherein the housing has a height of 58 mm, a bottom length of 180 mm, and a bottom width of 98 mm.

7. The drawer-type PCR tube cryopreservation cartridge as claimed in claim 1, wherein the upper drawer frame and the lower drawer frame are equal in height.

8. The drawer-type PCR tube cryopreservation box of claim 6, wherein 144 upper layer PCR tube limiting holes are formed in the upper drawer frame; 144 lower PCR tube limiting holes are formed in the lower drawer frame.

9. The drawer-type PCR tube cryopreservation box as claimed in claim 1, wherein the upper drawer frame and the lower drawer frame are provided with drawer sliding rails, a sliding groove is arranged on the inner wall of the outer shell, and the drawer sliding rails are in sliding fit with the sliding groove.

10. The drawer-type PCR tube cryopreservation cartridge as claimed in claim 9, wherein at least one end of the sliding groove is provided with a locking mechanism for locking the upper drawer frame and the lower drawer frame.