CN219474096U - Vacuum freeze drying device for biological enzyme detection - Google Patents

Abstract

The utility model provides a vacuum freeze drying device for biological enzyme detection, and belongs to the technical field of biological pharmaceutical instruments. The device comprises a base, wherein a box body is arranged on the base, one side of the box body is provided with a sealing door, two side walls connected with the sealing door in the box body are provided with heating resistance wires, a through hole is formed in the center of the top of the box body, a center column is arranged in the through hole in a penetrating mode, a plurality of layers of objective tables are arranged on the center column in a coaxial mode in the box body, one end of the center column outside the box body is fixedly connected with a rotating device, the center column is composed of a plurality of telescopic columns, limiting devices are arranged on the telescopic columns, the top of the box body is communicated with a refrigerator through a refrigerating pipeline, and the bottom of the box body is communicated with a vacuum pump. In the use process of the vacuum freeze drying device for biological enzyme detection, a plurality of parts of biological enzymes are sequentially placed on each layer of objective table, and the biological enzymes are started along with a rotating device to rotate around a central column during heating and drying, so that each layer of biological enzymes can be heated uniformly. Has the effect of improving the processing efficiency of biological enzymes.

Description

Vacuum freeze drying device for biological enzyme detection

Technical Field

The utility model relates to the technical field of biopharmaceutical instruments, in particular to a vacuum freeze drying device for biological enzyme detection.

Background

In biopharmaceutical manufacturing processes, it is often necessary to use biological enzymes. In the process of treating the biological enzyme, a work flow of freezing, drying and vacuumizing the biological enzyme by using a vacuum freeze drying device for detecting the biological enzyme is needed. Most of the water in the biological enzyme is removed by low-temperature freezing, then the biological enzyme is heated and dried by heating, and finally the vacuum is pumped.

The patent of the publication number CN217636693U of authorizing discloses a biological enzyme detects and uses vacuum freeze-drying device, including refrigerator, vacuum pump, freeze-drying cabinet body and motor, one side and refrigerator intercommunication, opposite side and vacuum pump intercommunication of freeze-drying cabinet body, the top is equipped with the heating lamp in the freeze-drying cabinet body, and the inner bottom of freeze-drying cabinet body is equipped with the dead lever, is equipped with spacing seat on the dead lever, and dead lever internally mounted has the threaded rod, and the output shaft of motor runs through freeze-drying cabinet body and threaded rod connection.

In the prior art, the vacuum freeze drying device for biological enzyme detection can uniformly heat the biological enzyme through a heating lamp, but only one biological enzyme can be placed at a time, so that the problem of low processing efficiency exists.

Disclosure of Invention

In view of the above, the present utility model provides a vacuum freeze-drying device for detecting biological enzymes.

In order to achieve the above purpose, the utility model adopts the following technical scheme:

the utility model provides a biological enzyme detects and uses vacuum freeze drying device, the on-line screen storage device comprises a base, be equipped with the box that is used for placing biological enzyme on the base, one side of box is established to the sealing door that is used for the switching box, be equipped with heating resistor silk on two lateral walls that meet with the sealing door in the box, the center department at box top is equipped with first through-hole, wear to be equipped with the center post in the first through-hole, the center post is equipped with the objective table that a plurality of layers are used for placing biological enzyme with the axle sleeve in the part of box, the center post is at the external one end fixedly connected with of box and is used for rotating the rotating device of center post, the top of box has the refrigerator that is used for carrying the air for the box through the refrigeration pipeline intercommunication, the bottom center department of box has the vacuum pump that is used for taking out the air in the box through the vacuum pipeline intercommunication.

Further, the rotating device comprises a fixed support, a motor is arranged on the fixed support, a first groove which is used for being matched with an output shaft of the motor is formed in one end of the central column outside the box body, and the first groove is fixedly connected with the output shaft of the motor through a bolt.

Further, the center column is established and inside hollow flexible post is constituteed by a plurality of coaxial cover, and two adjacent flexible posts divide into outer flexible post and inlayer flexible post because of the diameter difference, and flexible post is the same and the one-to-one with objective table quantity, is close to the one end and objective table fixed connection of bottom the box on the flexible post, is equipped with the stop device that is used for restricting coaxial gliding between the flexible post between every two-layer objective table on the flexible post.

Further, stop device includes the elasticity sheetmetal, and the elasticity sheetmetal is set firmly on the outer wall of the flexible post upper half, has set firmly the arch on the elasticity sheetmetal, and flexible post lower half is equipped with the second through-hole of at least two sizes and the protruding adaptation on the elasticity sheetmetal along vertical direction interval, and the upper half coaxial wearing of flexible post is established in the lower half of outer flexible post, through the protruding second through-hole joint of different co-altitude on the flexible post of the protruding and outer flexible post that removes on the elasticity sheetmetal to adjust the interval between the corresponding two-layer objective table.

Further, a second groove for fixing the biological enzyme container is formed in the objective table.

Further, the bottom wall in the box body is in a circular arc shape.

Further, an observation window for observing the internal condition of the box body is embedded on the sealing door.

The embodiment of the application provides a biological enzyme detects and uses vacuum freeze-drying device, the on-line screen storage device comprises a base, be equipped with the box that is used for placing biological enzyme on the base, one side of box is established to sealing door, be equipped with heating resistor silk on two lateral walls that meet with sealing door in the box, the center department at box top is equipped with the through-hole, wear to be equipped with the center post in the through-hole, the part coaxial sleeve in the box is equipped with a plurality of layers of objective tables on the center post, the center post is at the one end fixedly connected with rotating device outside the box, the center post comprises a plurality of telescopic links, be equipped with stop device on the telescopic links, there is the refrigerator at the top of box through the refrigeration pipeline intercommunication, there is the vacuum pump bottom center department of box through the vacuum pipeline intercommunication.

The beneficial effects of the utility model are as follows:

1. the multi-layer object stage is arranged in the box body, so that more biological enzymes can be treated simultaneously, and the production efficiency is improved;

2. in the use process of the vacuum freeze drying device for biological enzyme detection, when the biological enzyme is heated and dried, the motor is started to drive the center column to rotate, so that the biological enzyme on the object stage rotates and is heated uniformly;

3. the center column is composed of a plurality of telescopic columns, limiting devices are arranged on the telescopic columns, and the distance between the objective tables can be adjusted by coaxially sliding the telescopic columns so as to adapt to biological enzyme containers with different heights.

Drawings

Fig. 1 is a schematic plan view of a vacuum freeze-drying device for biological enzyme detection according to an embodiment of the present application.

Fig. 2 is a schematic diagram showing an internal structure of a casing of a vacuum freeze-drying apparatus for biological enzyme detection according to an embodiment of the present application.

Fig. 3 is a schematic structural diagram of a telescopic column limiting device of a vacuum freeze-drying device for biological enzyme detection according to an embodiment of the application.

Fig. 4 is a schematic view showing a stage structure of a vacuum freeze-drying device for biological enzyme detection according to an embodiment of the present application.

1, a base; 2. a case; 3. sealing the door; 4. heating the resistance wire; 5. a first through hole; 6. a center column; 7. an objective table; 8. a refrigerating machine; 9. a refrigeration valve; 10. a vacuum pump; 11. a vacuum valve; 12. a fixed bracket; 13. a motor; 14. an output shaft; 15. a first groove; 16. a telescopic column; 17. an elastic metal sheet; 18. a protrusion; 19. a second through hole; 20. a second groove; 21. and an observation window.

Detailed Description

In order to better understand the above technical solutions, the following detailed description will refer to the accompanying drawings and specific embodiments.

The embodiment of the application discloses a vacuum freeze drying device for biological enzyme detection. Referring to fig. 1 and 2, the biological enzyme box comprises a base 1, wherein a box body 2 for placing biological enzymes is connected to the base 1 through bolts, a sealing door 3 for opening and closing the box body 2 is arranged on one side of the box body 2, and in order to observe the processing condition of the biological enzymes in the box body 2 at any time, an observation window 21 is embedded in the sealing door 3, and the observation window 21 can be made of toughened glass. Two side walls of the box body 2, which are connected with the sealing door 3, are connected with heating resistance wires 4 through bracket bolts, and biological enzymes in the box body 2 can be heated and dried by opening the heating resistance wires 4. The center department at box 2 top has offered first through-hole 5, wears to be equipped with center post 6 in the first through-hole 5, for making the box 2 can process more biological enzymes simultaneously, and center post 6 is fixed with four-layer objective table 7 that are used for placing biological enzymes in the part an organic whole in box 2. In order to uniformly heat the biological enzyme on the object stage 7 during heating and drying, a rotating device for rotating the central column 6 is connected with one end of the central column 6 outside the box body 2 through bolts. The top of the box body 2 is communicated with a refrigerator 8 for conveying cold air to the box body 2 through a refrigerating pipeline, a refrigerating valve 9 for closing the refrigerating pipeline is arranged on the refrigerating pipeline, the refrigerator 8 is electrically connected with a controller, the controller can be a PLC, and the start and stop of the refrigerator 8 can be controlled through an internal program of the controller. The bottom center of the box body 2 is communicated with a vacuum pump 10 for exhausting air in the box body 2 through a vacuum pipeline, a vacuum valve 11 for closing the vacuum pipeline is arranged on the vacuum pipeline, the vacuum pump 10 is also electrically connected with a controller, and the start and stop of the refrigerator 8 can be controlled through an internal program of the controller.

Specifically, the rotating device comprises a fixed bracket 12, and a motor 13 is connected to the fixed bracket 12 through bolts. In order to fixedly connect the central column 6 with the output shaft 14 of the motor 13, a first groove 15 adapted to the output shaft 14 of the motor 13 is formed at one end of the central column 6 outside the box 2, and the first groove 15 on the central column 6 is fixedly connected with the output shaft 14 of the motor 13 through bolts. When the biological enzyme is heated and dried, the motor is started to drive the objective table on the center column to rotate, so that the biological enzyme on the objective table is heated uniformly.

In order to adjust the space between the object stages 7 at any time for adapting to biological enzyme containers with different heights, the central column 6 is provided with four telescopic columns 16 which are coaxially sleeved and hollow in the interior. Two adjacent telescopic columns 16 divide into outer telescopic column and inlayer telescopic column because of the diameter difference, and telescopic column 16 is the same and the one-to-one with objective table 7 quantity, and the one end that is close to box 2 bottom on the telescopic column 16 is fixed with corresponding objective table 7 an organic whole, is located between every two-layer objective table 7 on the telescopic column 16 and installs the stop device who is used for limiting coaxial slip between the telescopic column 16.

Referring to fig. 3, the limiting device includes an elastic metal sheet 17, the elastic metal sheet 17 is welded on the outer wall of the upper half of the telescopic column 16, and a protrusion 18 is integrally fixed on the elastic metal sheet 17. The lower half of the telescopic column 16 is provided with two second through holes 19 which are matched with the protrusions 18 on the elastic metal sheets 17 in size at intervals along the vertical direction, and the upper half of the telescopic column 16 is coaxially arranged on the lower half of the telescopic column 16 on the outer layer in a penetrating way. The distance between the corresponding two layers of object stages 7 is adjusted by moving the convex 18 on the metal sheet to be clamped with the second through holes 19 with different heights on the outer layer telescopic column 16.

Referring to fig. 4, during the start-up of the rotating means, the bio-enzyme on the stage 7 rotates around the center column 6, and in order to prevent the bio-enzyme from rotating and sliding out of the stage 7, a second recess 20 for fixing the bio-enzyme container is formed in the stage 7.

The refrigerator 8 refrigerates the biological enzyme in the box body 2, so that a large amount of water is separated out from the biological enzyme and is solidified on the surface of the biological enzyme. Then the refrigerator 8 is closed, the heating resistance wire 4 is opened, water mist is generated by absorbing heat of biological enzyme, and the inner bottom wall of the box body 2 is arc-shaped in order to facilitate the vacuum pump 10 to pump out the water mist and air in the box body 2.

The implementation principle of the vacuum freeze drying device for detecting the physical enzyme in the embodiment of the application is as follows: in the use process of the vacuum freeze-drying device for detecting the biological enzyme, firstly, a container containing the biological enzyme is placed in the second groove 20 of the objective table 7, then the sealing door 3 is closed, the refrigerator 8 is started to cool the inside of the box body 2, and ninety percent of water in the biological enzyme can be removed at minus thirty ℃. And then the refrigerator 8 is turned off, the heating resistance wire 4 in the box body 2 is started to heat and dry the biological enzyme, and the motor 13 is started in the heating process to enable the biological enzyme on the object stage 7 to rotate around the central column 6, so that the biological enzyme is heated rapidly and uniformly. And finally, closing the heating resistance wire, and opening the vacuum pump to pump out the air in the box body. The center column 6 is fixedly provided with a plurality of layers of object stages 7, so that more biological enzymes can be processed simultaneously, and the processing efficiency of the biological enzymes is improved.

It will be apparent to those skilled in the art that while preferred embodiments of the present utility model have been described, additional variations and modifications may be made to these embodiments once the basic inventive concepts are known to those skilled in the art. It is therefore intended that the following claims be interpreted as including the preferred embodiments and all such alterations and modifications as fall within the scope of the utility model. It will be apparent to those skilled in the art that various modifications and variations can be made to the present utility model without departing from the spirit or scope of the utility model. Thus, it is intended that the present utility model also include such modifications and alterations insofar as they come within the scope of the appended claims or the equivalents thereof.

Claims (7)

1. A vacuum freeze drying device for biological enzyme detection is characterized in that: including base (1), be equipped with box (2) that are used for placing biological enzyme on base (1), sealing door (3) for opening and shutting box (2) are established to one side of box (2), be equipped with heating resistor wire (4) on two lateral walls that meet with sealing door (3) in box (2), the center department at box (2) top is equipped with first through-hole (5), wear to be equipped with center post (6) in first through-hole (5), center post (6) are equipped with objective table (7) that a plurality of layers are used for placing biological enzyme with the axle sleeve in the part of box (2), the one end fixedly connected with outside box (2) of center post (6) is used for rotating center post (6) rotating device, the top of box (2) is equipped with refrigerator (8) that are used for carrying air for box (2) through the refrigeration pipeline intercommunication, the bottom center department of box (2) has vacuum pump (10) that are used for taking out the interior air of box (2) through the vacuum pipeline intercommunication.

2. The vacuum freeze-drying device for biological enzyme detection according to claim 1, wherein: the rotating device comprises a fixed support (12), a motor (13) is arranged on the fixed support (12), a first groove (15) which is used for being matched with an output shaft (14) of the motor (13) is formed in one end, outside the box body (2), of the center column (6), and the first groove (15) is fixedly connected with the output shaft (14) of the motor (13) through bolts.

3. The vacuum freeze-drying device for biological enzyme detection according to claim 1, wherein: the center column (6) is established and inside hollow flexible post (16) by a plurality of coaxial cover is constituteed, and two adjacent flexible posts (16) divide into outer flexible post and inlayer flexible post because of the diameter difference, the quantity of flexible post (16) and objective table (7) is the same and one-to-one, be close to the one end and the objective table (7) fixed connection that correspond of box (2) bottom on flexible post (16), be equipped with the stop device who is used for restricting coaxial slip between flexible post (16) between every two-layer objective table (7) on flexible post (16).

4. A vacuum freeze-drying device for biological enzyme detection according to claim 3, wherein: the limiting device comprises an elastic metal sheet (17), the elastic metal sheet (17) is fixedly arranged on the outer wall of the upper half part of the telescopic column (16), a protrusion (18) is fixedly arranged on the elastic metal sheet (17), the lower half part of the telescopic column (16) is provided with at least two second through holes (19) which are matched with the protrusions (18) on the elastic metal sheet (17) along the vertical direction at intervals, the upper half part of the telescopic column (16) is coaxially arranged on the lower half part of the telescopic column (16) of the outer layer in a penetrating mode, and the protrusions (18) on the elastic metal sheet (17) are connected with the second through holes (19) of different heights on the telescopic column (16) of the outer layer in a clamping mode to adjust the distance between the corresponding two layers of object stages (7).

5. The vacuum freeze-drying device for biological enzyme detection according to claim 1, wherein: the object stage (7) is provided with a second groove (20) for fixing the biological enzyme container.

6. The vacuum freeze-drying device for biological enzyme detection according to claim 1, wherein: the inner bottom wall of the box body (2) is arc-shaped.

7. The vacuum freeze-drying device for biological enzyme detection according to claim 1, wherein: an observation window (21) for observing the internal condition of the box body (2) is embedded in the sealing door (3).