CN219438024U - Cryopreservation box for immune cell cryopreservation bag - Google Patents

Cryopreservation box for immune cell cryopreservation bag Download PDF

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Publication number
CN219438024U
CN219438024U CN202223485615.7U CN202223485615U CN219438024U CN 219438024 U CN219438024 U CN 219438024U CN 202223485615 U CN202223485615 U CN 202223485615U CN 219438024 U CN219438024 U CN 219438024U
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China
Prior art keywords
cryopreservation
bearing
cover
shell
liquid inlet
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Active
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CN202223485615.7U
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Chinese (zh)
Inventor
徐立伟
于鹏初
曹继芳
郭静静
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Jilin Cangshe Biotechnology Co ltd
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Jilin Cangshe Biotechnology Co ltd
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02WCLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
    • Y02W90/00Enabling technologies or technologies with a potential or indirect contribution to greenhouse gas [GHG] emissions mitigation
    • Y02W90/10Bio-packaging, e.g. packing containers made from renewable resources or bio-plastics

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  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

The utility model relates to a cryopreservation box for an immune cell cryopreservation bag, which relates to the field of immune cell cryopreservation and solves the problems that in the prior art, cryopreservation liquid is directly put into a box body, then the cryopreservation bag filled with immune cells is put into the box body, but when the cryopreservation bag is taken out, workers are injured easily, and secondly, the temperature is not monitored in real time, stem cells are damaged easily due to too low temperature, and the cryopreservation bag is easy to damage when taken out. The technical characteristics include: a support base; the bearing structure is arranged on the upper surface of the supporting base and is used for bearing; and the retaining cover structure is arranged on the bearing structure. The temperature measuring structure is used for monitoring, so that the damage of immune cells caused by the too low temperature is prevented, the structure is relatively simple, and the use is convenient.

Description

Cryopreservation box for immune cell cryopreservation bag
Technical Field
The utility model relates to the technical field of immune cell cryopreservation, in particular to a cryopreservation box for an immune cell cryopreservation bag.
Background
Immune cells refer to cells involved in or associated with an immune response, including lymphocytes, dendritic cells, monocytes/macrophages, granulocytes, mast cells, etc., and can be classified into a variety of types, and in humans, various immune cells play an important role, commonly known as leukocytes, including congenital lymphocytes, various phagocytes, etc., and lymphocytes capable of recognizing antigens, producing specific immune responses, etc.
In the prior art, the cryopreservation liquid is directly put into the box body, and then the cryopreservation bag filled with immune cells is put into the box body, but when the cryopreservation bag is taken out again, the personnel are injured easily, secondly, the temperature is not monitored in real time, the stem cells are damaged easily because the temperature is too low, and the cryopreservation bag is also damaged easily when being taken out, so that the cryopreservation box for the immune cell cryopreservation bag is designed to solve the problem.
Disclosure of Invention
The utility model aims to solve the technical problems that in the prior art, cryopreservation liquid is directly put into a box body, then a cryopreservation bag filled with immune cells is put into the box body, but when the cryopreservation bag is taken out again, the personnel are easily injured, the temperature is not monitored in real time, stem cells are easily damaged due to the fact that the temperature is too low, and the cryopreservation bag is easily damaged when taken out.
In order to solve the technical problems, the technical scheme of the utility model is as follows:
a cryopreservation cassette for an immune cell cryopreservation bag, comprising:
a support base;
the bearing structure is arranged on the upper surface of the supporting base and is used for bearing;
the retaining cover structure is arranged on the bearing structure;
the heat insulation structure is arranged on the outer surface of the bearing structure and is used for heat insulation;
the cryopreservation structure is arranged on the bearing structure and is used for cryopreserving the cryopreserved immune cells;
the liquid inlet and outlet structure is arranged on the freezing storage structure, and extends out of the bearing structure;
the bearing structure is arranged on the cryopreservation structure and is used for bearing the immune cell cryopreservation bag;
the temperature measuring structure is arranged on the baffle cover structure and is used for measuring temperature.
Preferably, the load bearing structure comprises: a capless carrier housing;
the capless bearing shell is arranged on the upper surface of the supporting base.
Preferably, the blocking cover structure includes: the sealing buckle cover, the first heat preservation layer and the pair of fixing buckles;
the sealing buckle cover is hinged to the non-cover bearing shell, the first heat preservation layer is arranged on the lower surface of the sealing buckle cover, the pair of fixing buckles are arranged on the sealing buckle cover, and the pair of fixing buckles are connected with the non-cover bearing shell.
Preferably, the insulation structure comprises: a second heat-insulating layer;
the second heat preservation layer is arranged on the outer surface of the bearing structure.
Preferably, the cryopreservation structure comprises: the frozen stock solution bears the heat conduction shell;
the frozen stock bearing heat conducting shell is arranged in the non-cover bearing shell.
Preferably, the liquid inlet and outlet structure comprises: a liquid inlet pipe and a liquid outlet pipe and a sealing valve;
the liquid inlet and outlet pipe is arranged on the frozen stock solution bearing heat conduction shell, the liquid inlet and outlet pipe extends out of the non-cover bearing shell, and the sealing valve is arranged on the liquid inlet and outlet pipe.
Preferably, the housing structure includes: the device comprises a plurality of limit shells, handles matched with the limit shells, annular plates matched with the limit shells and bearing reticulated shells matched with the annular plates;
the handles are arranged on the upper surfaces of the corresponding limiting shells, the limiting shells can be overlapped together through the handles and placed on the inner sides of the freezing storage liquid bearing heat conducting shells, each pair of annular plates is arranged on the side surfaces of the corresponding limiting shells, and each bearing reticulated shell is arranged on the corresponding annular plate.
Preferably, the temperature measuring structure includes: temperature sensor, control display, battery box and loudspeaker;
the temperature sensor is arranged on the lower surface of the sealing buckle cover, a rectangular groove is formed in the upper surface of the sealing buckle cover, the control display is arranged at the rectangular groove, the battery box is connected with the temperature sensor and the control display, the loudspeaker is arranged at the rectangular groove, and the loudspeaker is connected with the control display and the battery box.
The utility model has the following beneficial effects:
this cryopreservation box that immune cell cryopreservation bag was used can be better freezes the immune cell, and is very convenient, has reduced unnecessary trouble, when taking out immune cell cryopreservation bag, has reduced staff's possibility of frostbite, monitors through temperature measurement structure, thereby prevents that the temperature from causing immune cell damage too low, and the structure is simple relatively, convenient to use.
Drawings
The utility model is described in further detail below with reference to the drawings and the detailed description.
FIG. 1 is a schematic view of a cryopreservation cassette for an immunocyte cryopreservation bag according to the present utility model;
FIG. 2 is a front view of a cryopreservation cassette for an immunocyte cryopreservation bag according to the present utility model;
FIG. 3 is a front view of a cryopreservation cassette for an immunocyte cryopreservation bag of the present utility model;
fig. 4 is a top view of a cryopreservation cassette for an immunocyte cryopreservation bag of the present utility model.
Reference numerals in the drawings denote:
the device comprises a supporting base 10, a bearing structure 20, a blocking cover structure 30, a heat preservation structure 40, a freezing storage structure 50, a liquid inlet and outlet structure 60, a bearing structure 70 and a temperature measurement structure 80;
a capless carrier housing 21;
a sealing buckle cover 31, a first heat insulation layer 32 and a fixing buckle 33;
a second insulating layer 41;
the frozen stock solution carries the heat conducting shell 51;
a liquid inlet and outlet pipe 61 and a sealing valve 62;
a limit housing 71, a handle 72, an annular plate 73, and a bearing net shell 74;
a temperature sensor 81, a control display 82, a battery box 83, and a speaker 84.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1-4, the carrying structure 20 on the upper surface of the supporting base 10 is used for carrying, the cover blocking structure 30 on the carrying structure 20 is used for blocking, the heat insulation structure 40 on the outer surface of the carrying structure 20 is used for heat insulation, the freezing structure 50 on the carrying structure 20 is used for freezing immune cells for freezing, the liquid inlet and outlet structure 60 on the freezing structure 50 is used for sending frozen liquid into or out of the freezing structure 50, the carrying structure 70 on the freezing structure 50 is used for carrying immune cell freezing bags, and the temperature measuring structure 80 on the cover blocking structure 30 is used for measuring temperature.
Preferably, the load bearing structure 20 comprises: a capless carrier housing 21; the capless carrier housing 21 is mounted to the upper surface of the support base 10.
Is carried by a capless carrier housing 21 supporting the upper surface of the base 10.
Preferably, the blocking cover structure 30 includes: a seal buckle cover 31, a first heat insulating layer 32, and a pair of fixing buckles 33; the sealing buckle cover 31 is hinged to the capless bearing shell 21, the first heat insulation layer 32 is installed on the lower surface of the sealing buckle cover 31, the pair of fixing buckles 33 are installed on the sealing buckle cover 31, and the pair of fixing buckles 33 are connected with the capless bearing shell 21.
The sealing buckle cover 31 on the non-cover bearing shell 21 is used for blocking, the first heat preservation layer 32 on the sealing buckle cover 31 is used for preserving heat, and the fixing buckle 33 on the sealing buckle cover 31 is used for controlling the opening and closing of the sealing buckle cover 31.
Preferably, the insulating structure 40 comprises: a second insulating layer 41; the second insulation layer 41 is mounted to the outer surface of the load bearing structure 20.
A second insulation layer 41 passing over the outer surface of the load bearing structure 20 is used for insulation.
Preferably, the cryopreservation structure 50 comprises: the frozen stock solution carries the heat conducting shell 51; the cryopreservation liquid bearing heat conductive housing 51 is mounted within the capless bearing housing 21.
The frozen stock solution is carried by the frozen stock solution carrying heat conduction housing 51 in the capless carrying housing 21, and heat conduction is performed, thereby performing frozen stock.
Preferably, the liquid inlet and outlet structure 60 comprises: a liquid inlet and outlet pipe 61 and a sealing valve 62; the liquid inlet and outlet pipe 61 is installed on the frozen stock solution bearing heat conducting shell 51, the liquid inlet and outlet pipe 61 extends out of the non-cover bearing shell 21, and the sealing valve 62 is installed on the liquid inlet and outlet pipe 61.
The sealing valve 62 on the liquid inlet and outlet pipe 61 is opened, frozen stock solution is fed into the frozen stock solution bearing heat conducting shell 51 through the liquid inlet and outlet pipe 61, then the sealing valve 62 on the liquid inlet and outlet pipe 61 is closed, when the frozen stock solution needs to be replaced, the sealing valve 62 on the liquid inlet and outlet pipe 61 is opened, and the original frozen stock solution is fed out for replacement.
Preferably, the mounting structure 70 includes: a plurality of limit cases 71, a handle 72 matched with the plurality of limit cases 71, an annular plate 73 matched with the plurality of limit cases 71, and a carrier web 74 matched with the plurality of annular plates 73. The handles 72 are mounted on the upper surfaces of the corresponding limiting shells 71, and the limiting shells 71 can be stacked together through the handles 72 and placed inside the freezing solution bearing heat conducting shell 51, each pair of annular plates 73 is mounted on the side surfaces of the corresponding limiting shells 71, and each bearing net shell 74 is mounted on the corresponding annular plate 73.
The immune cell cryopreservation bag is subjected to superposition limiting through the limiting shell 71, placed or taken out through the handle 72 on the limiting shell 71, and carried through the carrying net shell 74 on the annular plate 73.
Preferably, the temperature measuring structure 80 includes: a temperature sensor 81, a control display 82, a battery box 83, and a speaker 84; the temperature sensor 81 is installed on the lower surface of the sealing buckle cover 31, a rectangular groove is formed in the upper surface of the sealing buckle cover 31, the control display 82 is installed on the rectangular groove, the battery box 83 is connected with the temperature sensor 81 and the control display 82, the loudspeaker 84 is installed on the rectangular groove, and the loudspeaker 84 is connected with the control display 82 and the battery box 83.
The temperature sensor 81 on the lower surface of the sealing buckle cover 31 senses the temperature, the control display 82 on the sealing buckle cover 31 displays the temperature, the battery box 83 on the sealing buckle cover 31 supplies power, and when the temperature is insufficient, the control display 82 starts the loudspeaker 84 to remind.
It is apparent that the above examples are given by way of illustration only and are not limiting of the embodiments. Other variations or modifications of the above teachings will be apparent to those of ordinary skill in the art. It is not necessary here nor is it exhaustive of all embodiments. While still being apparent from variations or modifications that may be made by those skilled in the art are within the scope of the utility model.

Claims (8)

1. A cryopreservation cassette for an immune cell cryopreservation bag, comprising:
a support base (10);
a bearing structure (20), wherein the bearing structure (20) is arranged on the upper surface of the supporting base (10), and the bearing structure (20) is used for bearing;
the retaining cover structure (30), the retaining cover structure (30) is installed on the bearing structure (20);
the heat insulation structure (40), the heat insulation structure (40) is installed on the outer surface of the bearing structure (20), and the heat insulation structure (40) is used for heat insulation;
the cryopreservation structure (50), the cryopreservation structure (50) is arranged on the bearing structure (20), and the cryopreservation structure (50) is used for cryopreserving immune cells;
the liquid inlet and outlet structure (60), the liquid inlet and outlet structure (60) is arranged on the freezing storage structure (50), and the liquid inlet and outlet structure (60) extends out of the bearing structure (20);
a housing structure (70), the housing structure (70) being mounted on the cryopreservation structure (50), and the housing structure (70) being for housing an immune cell cryopreservation bag;
the temperature measuring structure (80), temperature measuring structure (80) is installed on fender lid structure (30), and temperature measuring structure (80) are used for the temperature measurement.
2. A cryopreservation cassette for an immunocyte cryopreservation bag according to claim 1, wherein the carrying structure (20) comprises: a capless carrier housing (21);
the capless bearing shell (21) is arranged on the upper surface of the supporting base (10).
3. The cryopreservation cassette for an immunocyte cryopreservation bag according to claim 2, wherein the cover structure (30) comprises: a sealing buckle cover (31), a first heat-preserving layer (32) and a pair of fixing buckles (33);
the sealing buckle cover (31) is hinged to the non-cover bearing shell (21), the first heat preservation layer (32) is installed on the lower surface of the sealing buckle cover (31), the pair of fixing buckles (33) are installed on the sealing buckle cover (31), and the pair of fixing buckles (33) are connected with the non-cover bearing shell (21).
4. A cryopreservation cassette for an immunocyte cryopreservation bag according to claim 2, wherein the insulating structure (40) comprises: a second insulating layer (41);
the second heat preservation layer (41) is arranged on the outer surface of the bearing structure (20).
5. A cryopreservation cassette for an immunocyte cryopreservation bag according to claim 2, wherein the cryopreservation structure (50) comprises: the frozen stock solution bears the heat conduction shell (51);
the frozen stock solution bearing heat conduction shell (51) is arranged in the non-cover bearing shell (21).
6. The cryopreservation cassette for an immunocyte cryopreservation bag according to claim 5, wherein said fluid access structure (60) comprises: a liquid inlet and outlet pipe (61) and a sealing valve (62);
the liquid inlet and outlet pipe (61) is arranged on the frozen stock solution bearing heat conducting shell (51), the liquid inlet and outlet pipe (61) extends out of the non-cover bearing shell (21), and the sealing valve (62) is arranged on the liquid inlet and outlet pipe (61).
7. The cryopreservation cassette for an immunocyte cryopreservation bag according to claim 5, wherein said housing structure (70) comprises: a plurality of limit cases (71), a handle (72) matched with the limit cases (71), an annular plate (73) matched with the limit cases (71), and a bearing net shell (74) matched with the annular plate (73);
the handles (72) are arranged on the upper surfaces of the corresponding limiting shells (71), the limiting shells (71) can be overlapped together through the handles (72) and placed on the inner side of the freezing storage liquid bearing heat conducting shell (51), each pair of annular plates (73) is arranged on the side surfaces of the corresponding limiting shells (71), and each bearing net shell (74) is arranged on the corresponding annular plate (73).
8. A cryopreservation cassette for an immunocyte cryopreservation bag according to claim 3, wherein said temperature measuring structure (80) comprises: a temperature sensor (81), a control display (82), a battery case (83), and a speaker (84);
the temperature sensor (81) is mounted on the lower surface of the sealing buckle cover (31), a rectangular groove is formed in the upper surface of the sealing buckle cover (31), the control display (82) is mounted on the rectangular groove, the battery box (83) is connected with the temperature sensor (81) and the control display (82), the loudspeaker (84) is mounted on the rectangular groove, and the loudspeaker (84) is connected with the control display (82) and the battery box (83).
CN202223485615.7U 2022-12-26 2022-12-26 Cryopreservation box for immune cell cryopreservation bag Active CN219438024U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202223485615.7U CN219438024U (en) 2022-12-26 2022-12-26 Cryopreservation box for immune cell cryopreservation bag

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202223485615.7U CN219438024U (en) 2022-12-26 2022-12-26 Cryopreservation box for immune cell cryopreservation bag

Publications (1)

Publication Number Publication Date
CN219438024U true CN219438024U (en) 2023-08-01

Family

ID=87381755

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202223485615.7U Active CN219438024U (en) 2022-12-26 2022-12-26 Cryopreservation box for immune cell cryopreservation bag

Country Status (1)

Country Link
CN (1) CN219438024U (en)

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