CN219434680U - Portable chemiluminescent detector - Google Patents

Portable chemiluminescent detector Download PDF

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Publication number
CN219434680U
CN219434680U CN202321609547.2U CN202321609547U CN219434680U CN 219434680 U CN219434680 U CN 219434680U CN 202321609547 U CN202321609547 U CN 202321609547U CN 219434680 U CN219434680 U CN 219434680U
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China
Prior art keywords
detection body
reaction cup
portable
plug
detection
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CN202321609547.2U
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Chinese (zh)
Inventor
孟雪
林青
吴红
王冰玥
赵悦
刘然
李孜琮
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BEIJING INSTITUTE OF METROLOGY
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BEIJING INSTITUTE OF METROLOGY
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The utility model relates to the technical field of detection equipment, in particular to a portable chemiluminescent detector, which comprises a darkroom box and a detection body, wherein the darkroom box is used for placing a liquid sample and a reagent, and the detection body is used for detecting light radiation generated when the liquid sample and the reagent react in the darkroom box; the darkroom box comprises a shell and a reaction cup, wherein the shell is detachably connected with the detection body, the reaction cup is arranged in the shell, and the reaction cup is used for placing a liquid sample and a reagent; the detection body is internally provided with a photomultiplier for detecting light radiation, the photomultiplier is electrically connected with a display screen arranged on the surface of the detection body, and the display screen is used for displaying detected data. The portable chemiluminescent detector provided by the utility model has the advantages that the photomultiplier detects the light radiation generated by the reaction of the solution and the reagent in the darkroom box, and converts the light signal into an electric signal to be transmitted to the display screen, so that the aim of carrying out chemiluminescent detection on site is fulfilled.

Description

Portable chemiluminescent detector
Technical Field
The utility model relates to the technical field of detection equipment, in particular to a portable chemiluminescent detector.
Background
Chemiluminescence is the emission of light produced by chemical reactions at ambient temperature, and is a multi-step process in which some compounds use the energy produced by chemical reactions to raise their product molecules or intermediate molecules to an electronically excited state, and when the product molecules or intermediate molecules decay to the ground state, energy is released (i.e., luminescence) in the form of emission molecules.
Chemiluminescence analysis is to utilize the catalysis of a chemiluminescent substance through a catalyst and the oxidation of an oxidant to form an excited intermediate, and when the excited intermediate returns to a stable ground state, photons are emitted simultaneously, and the yield of light quanta is measured by a luminescence signal measuring instrument. The chemiluminescence method is widely applied to the fields of trace metal ion detection, inorganic compound and organic compound analysis, biological clinic and the like.
At present, the chemiluminescent analyzer has the characteristics of high sensitivity, high automation degree, high batch sample processing speed and the like, and becomes the mainstream of immunoassay diagnosis. However, the traditional large-scale full-automatic chemiluminescence immunoassay instrument has the defects of complex equipment, huge volume, high cost and the like, can only detect at the place where the equipment is placed, has certain limitation on application scenes, cannot detect at any time and any place on site, and has the limitation on application range and development and popularization due to high cost.
In view of the foregoing, there is a need for a portable chemiluminescent detector.
Disclosure of Invention
The utility model aims to provide a portable chemiluminescent detector, which solves the technical problem that chemiluminescent detection is inconvenient to carry out on site in the prior art.
In order to solve the technical problems, the portable chemiluminescent detector provided by the utility model comprises a darkroom box and a detection body, wherein the darkroom box is used for placing a liquid sample and a reagent, and the detection body is used for detecting optical radiation during chemical reaction of the liquid sample and the reagent in the darkroom box;
the darkroom box comprises a shell and a reaction cup, wherein the shell is detachably connected with the detection body, the reaction cup is arranged in the shell, and the reaction cup is used for placing a liquid sample and a reagent;
the detection body is internally provided with a photomultiplier for detecting light radiation, the photomultiplier is electrically connected with a display screen arranged on the surface of the detection body, and the display screen is used for displaying detected data.
Through the technical scheme, when the detection is carried out on site or in a laboratory, firstly, the solution to be detected is placed in the reaction cup, then the detection reagent is added into the reaction cup, then the darkroom box is moved to be abutted with the detection body, the darkroom box is fixed with the detection body, the photomultiplier in the detection body is utilized to detect the optical radiation of the solution in the darkroom box and the reagent in the chemical reaction, the photomultiplier converts the detected weak optical signal into an electric signal and then transmits the electric signal to the display screen which is electrically connected, so that the purpose of carrying out the chemiluminescence detection on site is achieved, and the product can also be used in the laboratory.
Preferably, the material of the darkroom box is a darkroom box made of shading materials.
Further, the detection window is opened at one end of the detection body, which is close to the darkroom box, and the photomultiplier in the detection body detects the chemical reaction in the darkroom box through the detection window, and the detection window is internally provided with an opening and closing plate, and the opening and closing plate is used for sealing the detection window when the darkroom box is far away from the detection body.
Through the technical scheme of above-mentioned improvement, when the darkroom box kept away from the detection body, open and close board sealed detection window, avoid light to cause the damage to detecting the photomultiplier in the body.
Further, the detection body is in threaded connection with the shell.
Through above-mentioned modified technical scheme, rotate shell and detect body threaded connection, promote the airtight between detection body and the outside, strengthen its shading performance.
Furthermore, the detection body is in plug-in fit with the shell.
Through the technical scheme of the improvement, the shell is pushed to be in plug-in fit with the detection body, so that the shell is in airtight connection with the detection body.
Further, a sealing strip is arranged between the detection body and the shell and is used for sealing a gap between the detection body and the shell.
Through the technical scheme of the improvement, the sealing strip is used for sealing the gap between the shell and the detection body, so that the shading performance of the detection body is enhanced.
Further, an operation button is arranged below the display screen and used for controlling the opening and closing of the detection body.
Further, the outer side wall of keeping away from the display screen of detecting the body is provided with the exhaust hole, and the exhaust hole is used for discharging the heat that the detector during operation produced.
Further, the reaction cup is detachably connected with the shell.
Through the technical scheme, the reaction cup and the shell are detachably connected, and when the reaction cup needs to be detected for many times, the standby reaction cup can be directly replaced to start the next detection.
Further, be provided with grafting subassembly between reaction cup and the shell, grafting subassembly includes grafting groove and grafting piece, and the lateral wall at the shell is seted up to the grafting groove, grafting piece and reaction cup fixed connection, grafting piece and grafting groove grafting cooperation.
Further, the lateral wall of grafting groove is provided with the joint groove, and joint groove and grafting groove intercommunication for in the joint piece was followed the grafting inslot of slip to the joint groove, joint piece and joint groove joint cooperation, the joint groove is used for spacing the joint piece.
Through the improved technical scheme, when the reaction cup is connected in the shell, the reaction cup is moved into the shell, the plug-in block is aligned with the plug-in groove, the plug-in block is pushed to be plugged in the plug-in groove and slide in the plug-in groove, and when the plug-in block is aligned with the plug-in groove, the reaction cup is rotated to drive the plug-in block to be clamped in the clamping groove, and the clamping groove is utilized to limit the plug-in block, so that the reaction cup is fixed in the shell; when the reaction cup is taken out from the shell, the reaction cup is reversely rotated to drive the plug-in block to slide out of the clamping groove into the plug-in groove, and then the reaction cup is pulled upwards to drive the plug-in block to be plugged into the plug-in groove to slide until the plug-in block slides out of the plug-in groove, so that the reaction cup is separated from the shell.
Further, a limiting rod is arranged between the reaction cup and the shell and is rotationally connected with the top end of the shell, and the limiting rod is abutted with the top end of the reaction cup.
Through the technical scheme of the improvement, the reaction cup is placed in the shell, then the limiting rod is rotated to the top end of the reaction cup, and the reaction cup is fixed in the shell by the limiting rod.
Furthermore, the reaction cup is provided with a kit in a matching way, and a reagent for adding into the reaction cup is placed in the kit.
Preferably, the kit comprises a luminol kit for detecting blood, heavy metals and trace Cd 2+ And hexavalent chromium, the luminol kit comprises a component A: a solution of luminol powder and sodium hydroxide or sodium carbonate.
Preferably, the luminol kit comprises a component B: adding a small amount of sodium stannate, sodium pyrophosphate or 8-hydroxyquinoline and the like into 30% hydrogen peroxide or hydrogen peroxide diluent, wherein the component B is used as an oxidant.
Preferably, component B may also be a solid peroxide or other oxidizing agent, component B being BaO 2 、MgO 2 Graphene oxide or vanadyl acetylacetonate.
Preferably, the luminol kit can be added with an enhancer, wherein the enhancer is p-iodophenol, p-phenylphenol or periodic acid and the like.
Preferably, quantum dots can be added into the luminol kit to improve sensitivity, wherein the quantum dots are graphene quantum dots, ceTe quantum dots and the like.
Preferably, the kit further comprises a luminol-EDTA-nanoparticle system kit for detecting caffeic acid and rutin, wherein the nanoparticle is nano ZnO and nano Fe 3 O 4 Nano CuFe 2 O 4 Etc.
By adopting the technical scheme, the utility model has the following beneficial effects:
according to the portable chemiluminescent detector provided by the utility model, through the improved technical scheme, when the detection is carried out on site or in a laboratory, firstly, a solution to be detected is placed in a reaction cup, then a detection reagent is added into the reaction cup, then a darkroom box is moved to be abutted against a detection body, the darkroom box is fixed with the detection body, the photomultiplier in the detection body is utilized to detect the optical radiation of the solution in the darkroom box and the reagent in the chemical reaction, the photomultiplier converts the detected weak optical signal into an electric signal and then transmits the electric signal to an electrically connected display screen for chemiluminescent detection, and the portable chemiluminescent detector can be used for site quick detection and laboratory detection, can be applied to the fields of environmental monitoring, forensic criminal investigation, in-vitro diagnosis and the like, and achieves the purpose of carrying out chemiluminescent detection on site.
Drawings
In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings which are required in the description of the embodiments or the prior art will be briefly described, it being obvious that the drawings in the description below are some embodiments of the utility model and that other drawings may be obtained from these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram of a portable chemiluminescent detector according to an embodiment of the present utility model;
FIG. 2 is a schematic diagram showing the threaded connection of the darkroom box and the detecting body;
FIG. 3 is a schematic diagram of a portable chemiluminescent detector;
FIG. 4 is a schematic diagram showing the plug-in connection of the darkroom box and the detecting body;
FIG. 5 is a schematic diagram of the structure of the plug-in fit of the shell and the reaction cup;
FIG. 6 is a schematic diagram showing the structure of the clamping groove;
FIG. 7 is a schematic view of the structure of the shell and the reaction cup connected by a limiting rod;
FIG. 8 is a schematic view of the structure of the rotary limiting rod for taking the reaction cup out of the shell.
Reference numerals:
1. a darkroom box; 11. a housing; 12. a reaction cup; 2. detecting a body; 21. a display screen; 22. operating a button; 3. a sealing strip; 4. a plug assembly; 41. a plug-in groove; 42. a plug block; 5. a clamping groove; 6. and a limit rod.
Detailed Description
The following description of the embodiments of the present utility model will be made apparent and fully in view of the accompanying drawings, in which some, but not all embodiments of the utility model are shown. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
In the description of the present utility model, it should be noted that the directions or positional relationships indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. are based on the directions or positional relationships shown in the drawings, are merely for convenience of describing the present utility model and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present utility model. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present utility model, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present utility model will be understood in specific cases by those of ordinary skill in the art.
The utility model is further illustrated with reference to specific embodiments.
As shown in fig. 1-4, the portable chemiluminescent detector provided in this embodiment includes a darkroom box 1 and a detecting body 2, wherein the darkroom box 1 is made of a shading material, the darkroom box 1 is used for placing a liquid sample and a reagent, and the detecting body 2 is used for detecting optical radiation during a chemical reaction of the liquid sample and the reagent in the darkroom box 1;
the darkroom box 1 comprises a shell 11 and a reaction cup 12, wherein the shell 11 is made of shading materials and is used for forming a darkroom, the shell 11 is detachably connected with the detection body 2, the reaction cup 12 is arranged in the shell 11, and the reaction cup 12 is used for placing liquid samples and reagents;
the detection body 2 is internally provided with a photomultiplier tube for detecting light radiation, the photomultiplier tube is electrically connected with a display screen 21 arranged on the surface of the detection body 2, and the display screen 21 is used for displaying detected data.
The detection window is opened at one end of the detection body 2, which is close to the darkroom box 1, and the photomultiplier in the detection body 2 detects the chemical reaction of the reaction cup 12 in the darkroom box 1 through the detection window, and the detection window is internally provided with an opening and closing plate which is used for sealing the detection window when the darkroom box 1 is far away from the detection body 2. When the darkroom box 1 is far away from the detection body 2, the detection window is sealed by the opening and closing plate, so that the damage of light to the photomultiplier in the detection body 2 is avoided; after the darkroom box 1 is installed with the detection body 2, the detection body 2 is started to automatically open the opening and closing plate, so that the photomultiplier in the detection body 2 detects the chemical reaction of the reaction cup 12.
As shown in fig. 1 and 2, the detecting body 2 is in threaded connection with the housing 11; as shown in fig. 3 and 4, the detecting body 2 is in plug-in fit with the housing 11, a sealing strip 3 is arranged between the detecting body 2 and the housing 11, and the sealing strip 3 is used for sealing a gap between the detecting body 2 and the housing 11.
As shown in fig. 4, an operation button 22 is arranged below the display screen 21 for controlling the opening and closing of the detecting body 2; the outer side wall of the detection body 2 far away from the display screen 21 is provided with an exhaust hole, and the exhaust hole is used for exhausting heat generated during the operation of the detector.
As shown in fig. 5 and 6, the reaction cup 12 is detachably connected with the housing 11; be provided with grafting subassembly 4 between reaction cup 12 and the shell 11, grafting subassembly 4 includes grafting groove 41 and grafting piece 42, the lateral wall at shell 11 is seted up to grafting groove 41, grafting piece 42 and reaction cup 12 fixed connection, grafting piece 42 and grafting groove 41 grafting cooperation, the lateral wall of grafting groove 41 is provided with joint groove 5, joint groove 5 and grafting groove 41 intercommunication for in the grafting piece 42 is followed grafting groove 41 internal sliding to joint groove 5, grafting piece 42 and joint groove 5 joint cooperation, joint groove 5 is used for spacing grafting piece 42.
As shown in fig. 7 and 8, a stopper rod 6 is provided between the reaction cup 12 and the housing 11, the stopper rod 6 is rotatably connected to the top end of the housing 11, and the stopper rod 6 abuts against the top end of the reaction cup 12.
The portable luminescence detector in this embodiment is provided with a kit in which a reagent for addition in the reaction cup 12 is placed. The kit comprises two types: the first kit is a luminol kit, and the luminol kit is used for detecting blood, heavy metals and trace Cd 2+ And hexavalent chromium, the luminol kit comprises a component A: a solution of luminol powder and sodium hydroxide or sodium carbonate.
The luminol kit comprises a component B: adding a trace amount of sodium stannate, sodium pyrophosphate or 8-hydroxyquinoline and the like into 30% hydrogen peroxide or hydrogen peroxide diluent, and taking the component B as an oxidant to improve the chemiluminescence reaction; component B may also be a solid peroxide or other oxidizing agent, component B being BaO 2 、MgO 2 Graphene oxide or vanadyl acetylacetonate; the luminol kit can also be added with an enhancer, wherein the enhancer is p-iodophenol, p-phenylphenol or periodic acid and the like. The luminol kit can be added withThe sensitivity is improved by the quantum dots, wherein the quantum dots are graphene quantum dots, ceTe quantum dots and the like.
The second kit is a luminol-EDTA-nanoparticle system kit, and the luminol-EDTA-nanoparticle system kit is used for detecting caffeic acid and rutin, wherein the nanoparticles are nano ZnO and nano Fe 3 O 4 Nano CuFe 2 O 4 Etc.
The implementation principle of the portable chemiluminescent detector provided by the embodiment of the utility model is as follows: when the detection is carried out on site or in a laboratory, firstly, a solution to be detected is placed in a reaction cup 12, then a detection reagent is added into the reaction cup 12, then a darkroom box 1 is moved to be abutted against a detection body 2, and the darkroom box 1 is in threaded connection with the detection body 2 through rotating the darkroom box 1 or pushing the darkroom box 1 to be inserted into the detection body 2 so as to enable the darkroom box 1 to be fixedly connected with the detection body 2; then, the detection body 2 is started by operating the button 22, and the photomultiplier in the detection body 2 is used for detecting the optical radiation generated during the chemical reaction of the solution and the reagent in the darkroom box 1, and the photomultiplier converts the detected weak optical signal into an electric signal and then transmits the electric signal to the display screen 21 which is electrically connected, so that the chemiluminescence detection is completed.
When multiple detection is needed, the detected darkroom box 1 is taken down from the detection body 2, then the reaction cup 12 is reversely rotated to drive the plug-in block 42 to slide out of the clamping groove 5 into the plug-in groove 41, and then the reaction cup 12 is pulled upwards to drive the plug-in block 42 to be plugged into the plug-in groove 41 to slide until the plug-in block 42 slides out of the plug-in groove 41, so that the reaction cup 12 is separated from the shell 11; when the new reaction cup 12 is moved into the shell 11, the plug-in block 42 is aligned with the plug-in groove 41, the plug-in block 42 is pushed to be plugged into the plug-in groove 41 and slide in the plug-in groove 41, and when the plug-in block 42 is aligned with the plug-in groove 41, the reaction cup 12 is rotated to drive the plug-in block 42 to be clamped into the clamping groove 5, and the clamping groove 5 is utilized to limit the plug-in block 42, so that the reaction cup 12 is fixed in the shell 11.
Or, the reaction cup 12 is taken out from the shell 11 after the reaction cup 12 is rotated to be far away from the top end of the reaction cup 12, then a new reaction cup 12 is placed in the shell 11, then the reaction cup 12 is fixed in the shell 11 by the limit rod 6 until the top end of the reaction cup 12 is rotated, and the detection steps are continuously repeated to perform luminescence detection again.
Experiment one: the solution suspected of containing blood is tested.
The luminol reagent kit is added into the reaction cup 12, then a liquid sample suspected to contain blood is added, then the darkroom box 1 is moved to the position of the detection body 2, the darkroom box 1 is fixedly connected with the detection body 2, the detection body 2 is opened by operating the button 22, and whether the blood is contained or not can be detected by using the detector by amplifying signals by using the photomultiplier.
Experiment II: detection of solutions suspected of containing heavy metals
Adding a luminol kit into a reaction cup 12, adding a liquid sample of a solution suspected to contain heavy metals, then moving the darkroom box 1 to the detection body 2, connecting and fixing the darkroom box 1 and the detection body 2, opening the detection body 2 through an operation button 22, amplifying signals by utilizing a photomultiplier, enabling the detector to detect whether the solution contains the heavy metals, and comparing the standard curve with the standard curve, so that the heavy metal content can be calculated.
Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present utility model, and not for limiting the same; although the utility model has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some or all of the technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit of the utility model.

Claims (10)

1. The portable chemiluminescent detector is characterized by comprising a darkroom box (1) and a detection body (2), wherein the darkroom box (1) is used for placing a liquid sample and a reagent, and the detection body (2) is used for detecting optical radiation generated during chemical reaction of the liquid sample and the reagent in the darkroom box (1);
the darkroom box (1) comprises a shell (11) and a reaction cup (12), wherein the shell (11) is detachably connected with the detection body (2), the reaction cup (12) is arranged in the shell (11), and the reaction cup (12) is used for placing a liquid sample and a reagent;
the detection body (2) is internally provided with a photomultiplier for detecting light radiation in the reaction cup (12), the photomultiplier is electrically connected with a display screen (21) arranged on the surface of the detection body (2), and the display screen (21) is used for displaying detected data.
2. The portable chemiluminescent detector of claim 1 wherein a detection window is provided at one end of the detection body (2) adjacent to the darkroom box (1), a photomultiplier tube in the detection body (2) detects a chemical reaction in the darkroom box (1) through the detection window, an opening and closing plate is provided in the detection window, and the opening and closing plate is used for sealing the detection window when the darkroom box (1) is far away from the detection body (2).
3. The portable chemiluminescent detector of claim 1 wherein the detection body (2) is a plug-fit with the housing (11).
4. A portable chemiluminescent detector according to claim 3 wherein a sealing strip (3) is provided between the detection body (2) and the housing (11), the sealing strip (3) being used to seal a gap between the detection body (2) and the housing (11).
5. The portable chemiluminescent detector of claim 1 wherein an operating button (22) is provided below the display screen (21) for controlling the opening and closing of the detection body (2).
6. The portable chemiluminescent detector of claim 1 wherein the outer side wall of the detection body (2) remote from the display screen (21) is provided with an exhaust vent for exhausting heat generated during operation of the detector.
7. The portable chemiluminescent detector of claim 1 wherein the reaction cup (12) is removably attached to the housing (11) to facilitate replacement of the reaction cup (12) for repeated testing.
8. The portable chemiluminescent detector of claim 7 wherein a plug assembly (4) is disposed between the reaction cup (12) and the housing (11), the plug assembly (4) comprises a plug slot (41) and a plug block (42), the plug slot (41) is formed in a side wall of the housing (11), the plug block (42) is fixedly connected with the reaction cup (12), and the plug block (42) is in plug fit with the plug slot (41).
9. The portable chemiluminescent detector of claim 8 wherein a clamping groove (5) is provided on a side wall of the plugging groove (41), the clamping groove (5) is communicated with the plugging groove (41) and is used for sliding the plugging block (42) into the clamping groove (5) from the plugging groove (41), the plugging block (42) is in clamping fit with the clamping groove (5), and the clamping groove (5) is used for limiting the plugging block (42).
10. The portable chemiluminescent detector of claim 7 wherein a stop lever (6) is disposed between the reaction cup (12) and the housing (11), the stop lever (6) being rotatably connected to the top end of the housing (11), the stop lever (6) being in abutment with the top end of the reaction cup (12).
CN202321609547.2U 2023-06-25 2023-06-25 Portable chemiluminescent detector Active CN219434680U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202321609547.2U CN219434680U (en) 2023-06-25 2023-06-25 Portable chemiluminescent detector

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202321609547.2U CN219434680U (en) 2023-06-25 2023-06-25 Portable chemiluminescent detector

Publications (1)

Publication Number Publication Date
CN219434680U true CN219434680U (en) 2023-07-28

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