CN219434679U

CN219434679U - Novel two-step two-separation high-efficiency chemiluminescent analyzer

Info

Publication number: CN219434679U
Application number: CN202320614705.7U
Authority: CN
Inventors: 易剑峰; 李文佳; 汪志义; 徐焕华; 林色奇
Original assignee: Jiangxi University of Traditional Chinese Medicine
Current assignee: Jiangxi University of Traditional Chinese Medicine
Priority date: 2023-03-24
Filing date: 2023-03-24
Publication date: 2023-07-28
Anticipated expiration: 2033-03-24

Abstract

The utility model discloses a novel two-step two-separation high-efficiency chemiluminescent analyzer, which relates to the technical field of chemiluminescent analyzers and comprises an analyzer body, wherein the top of the analyzer body is fixedly connected with a bottom plate, an inserting cylinder is arranged above the bottom plate, a buffer component is arranged at the bottom of the inserting cylinder and comprises a telescopic piece, a spring and a sliding plate, the sliding plate is slidingly connected inside the inserting cylinder, one end of the telescopic piece is fixedly connected at the bottom of the inserting cylinder, the other end of the telescopic piece is fixedly connected with the lower surface of the sliding plate, the spring is sleeved outside the telescopic piece, one end of the spring is fixedly connected at the bottom of the inserting cylinder, the other end of the spring is fixedly connected at the lower surface of the sliding plate, and an extrusion component is arranged above the inserting cylinder. The novel two-step two-separation high-efficiency chemiluminescent analyzer has the advantages that the test tube can move up and down in the rotation separation process, and the separation efficiency is improved.

Description

Novel two-step two-separation high-efficiency chemiluminescent analyzer

Technical Field

The utility model relates to the technical field of chemiluminescent analyzers, in particular to a novel two-step two-separation high-efficiency chemiluminescent analyzer.

Background

Chemiluminescence analysis is a method of performing chemical analysis using chemiluminescence. The chemical reaction can produce a product in an electron excited state, and when the product molecule undergoes a radiative transition or energy is transferred to other molecules which emit light, the molecule undergoes a radiative transition again, a light emitting phenomenon occurs. This phenomenon in which molecules are excited by electrons to emit light due to absorption of chemical energy is called chemiluminescence. The sensitivity of chemiluminescence analysis is high, and the chemiluminescence analysis is one of important means of trace analysis, and is widely applied to the fields of environmental monitoring, clinical analysis, biochemistry and the like, such as pollutant determination, enzyme analysis, immunoassay, trace metal analysis and the like.

The separation device of the nanometer magnetic beads is a necessary component in the chemiluminescence analyzer, reduces the labor intensity of medical staff, and can avoid experimental errors caused by incomplete separation. The separation device in the existing chemiluminescence analyzer is lack of extrusion protection on the top of a test tube, so that liquid is prevented from splashing out of the test tube in separation operation, the normal rotating speed cannot be too high, the separation time is further prolonged, and the analysis efficiency can be affected by long-time separation operation.

Therefore, it is necessary to invent a novel two-step two-separation high-efficiency chemiluminescent analyzer to solve the above problems.

Disclosure of Invention

The utility model aims to provide a novel two-step two-separation high-efficiency chemiluminescent analyzer so as to solve the problems in the background technology.

In order to achieve the above purpose, the present utility model provides the following technical solutions: the utility model provides a novel two high-efficient chemiluminescence analyzer of two steps, includes the analyzer body, the top fixedly connected with bottom plate of analyzer body, the top of bottom plate is provided with inserts a section of thick bamboo, it is provided with buffer assembly to insert a section of thick bamboo bottom, buffer assembly includes expansion member, spring and slide, slide sliding connection is inserting the inside of section of thick bamboo, the one end fixed connection of expansion member is inserting a section of thick bamboo bottom, the other end fixed connection of expansion member is at the lower surface of slide, the spring suit is in the outside of expansion member, the one end fixed connection of spring is inserting a section of thick bamboo bottom, the other end fixed connection of spring is at the lower surface of slide, the top of inserting a section of thick bamboo is provided with extrusion assembly.

Preferably, the bottom of the insertion barrel is provided with a round groove, a round rod is connected inside the round groove in a sliding mode, the upper surface of the bottom plate is fixedly connected with a motor, a chassis is fixedly connected to a driving shaft of the motor, and the bottom of the round rod is fixedly connected to the chassis.

Preferably, the outside fixedly connected with diaphragm of a section of thick bamboo inserts, the lower surface fixedly connected with electric putter of diaphragm, electric putter keeps away from the one end fixed connection of diaphragm on the chassis.

Preferably, an observation port is formed in the wall body of the insertion barrel.

Preferably, a top ring is arranged above the chassis, the top ring and the chassis are correspondingly distributed, the lower surface of the top ring is provided with a ring groove, the inner walls of the two sides of the ring groove are provided with a plurality of groups of sliding grooves and arc grooves, the sliding grooves and the arc grooves are distributed in a staggered manner, and the sliding grooves are communicated with the arc grooves.

Preferably, the extrusion assembly comprises a pressing column, a connecting rod, a sliding block and two convex blocks, wherein the two convex blocks are respectively and fixedly connected to two ends of the sliding block, the convex blocks are slidably connected in the sliding groove and the arc groove, one end of the connecting rod is fixedly connected to the lower surface of the sliding block, and the other end of the connecting rod is fixedly connected to the upper surface of the pressing column.

Preferably, the lower surface of the pressing column is fixedly connected with a second rubber pad, and the upper surface of the sliding plate is fixedly connected with a first rubber pad.

Preferably, the upper surface fixedly connected with gallows of bottom plate, the lower surface fixedly connected with hydraulic stem at gallows top, the bottom fixedly connected with fixed plate of hydraulic stem, fixed plate fixed connection is on the inner race of top ring.

The utility model has the technical effects and advantages that:

1. placing the test tube inside inserting the section of thick bamboo, electric putter passes through the diaphragm and drives and insert a section of thick bamboo upward movement, and the pressure post inserts to insert inside the section of thick bamboo, extrudees fixedly from the test tube top, improves the stability of separation. The motor rotates to drive the chassis to rotate, and then drives the cartridge and the test tube inside to rotate, rotates the separation to the nanometer magnetic bead inside the reagent. Because the sliding grooves and the arc grooves on the top ring are distributed in a staggered manner, the convex blocks can alternately slide in the sliding grooves and the arc grooves to drive the sliding blocks to move up and down, further drive the pressing columns to move up and down, and the buffer assemblies are matched to enable the test tubes to move up and down, so that the test tubes can also move up and down in the rotation and separation process, and the separation efficiency is improved.

Drawings

FIG. 1 is a schematic diagram of a novel two-step, two-separation, high-efficiency chemiluminescent analyzer of the present utility model.

FIG. 2 is a schematic view of the structure of the base plate, the bottom plate, the top ring and the extrusion assembly of the present utility model.

FIG. 3 is a schematic view showing the structure of the top ring, the ring groove and the pressing assembly according to the present utility model.

Fig. 4 is a schematic view of the top ring, ring groove, sliding groove and arc groove structure of the present utility model.

FIG. 5 is a schematic view of the extrusion assembly of the present utility model.

FIG. 6 is a schematic view of the cartridge and buffer assembly of the present utility model.

In the figure: 1. an analyzer body; 2. a bottom plate; 3. a plug cylinder; 4. an observation port; 5. a telescoping member; 6. a spring; 7. a circular groove; 8. a cross plate; 9. an electric push rod; 10. a round bar; 11. a chassis; 12. a top ring; 13. a ring groove; 14. a chute; 15. an arc groove; 16. pressing a column; 17. a connecting rod; 18. a slide block; 19. a bump; 20. a first rubber pad; 21. a second rubber pad; 22. a fixing plate; 23. a hydraulic rod; 24. a hanging bracket; 25. a slide plate; 26. and a motor.

Detailed Description

The technical solutions in the embodiments of the present utility model will be made clear below in conjunction with the drawings in the embodiments of the present utility model; it will be apparent that the embodiments described are only some, but not all, of the embodiments of the utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

The utility model provides a novel two-step two-separation high-efficiency chemiluminescent analyzer as shown in fig. 1-6, which comprises an analyzer body 1, wherein the top of the analyzer body 1 is fixedly connected with a bottom plate 2. The upper side of the bottom plate 2 is provided with a cartridge 3, and the test tube is placed inside the cartridge 3 during separation operation. The bottom of the insertion cylinder 3 is provided with a buffer assembly which comprises a telescopic piece 5, a spring 6 and a sliding plate 25. When the protruding block 19 slides in the sliding groove 14 and the arc groove 15, the sliding groove 14 and the arc groove 15 are distributed in a staggered mode, so that the pressing column 16 moves up and down, the buffer assembly is matched to enable the test tube to move up and down, the test tube can also move up and down in the rotating process, and the separation efficiency of the nano magnetic beads is improved. Slide 25 sliding connection is in the inside of inserting a section of thick bamboo 3, and the one end fixed connection of extensible member 5 is in the bottom of inserting a section of thick bamboo 3, and the other end fixed connection of extensible member 5 is in the lower surface of slide 25, and spring 6 suit is in the outside of extensible member 5, and the one end fixed connection of spring 6 is in the bottom of inserting a section of thick bamboo 3, and the other end fixed connection of spring 6 is in the lower surface of slide 25. Along with the up-and-down movement of the compression column 16, the spring 6 and the telescopic piece 5 are matched with the compression column 16 to reciprocate. The top of cartridge 3 is provided with extrusion subassembly, and buffer assembly is used for extruding from the test tube top, improves the stability of test tube rotation in-process.

When the extrusion assembly is specifically arranged, the extrusion assembly comprises a pressing column 16, a connecting rod 17, a sliding block 18 and a protruding block 19, and the protruding blocks 19 are arranged in two groups. Two groups of protruding blocks 19 are respectively and fixedly connected to two ends of the sliding block 18, and the protruding blocks 19 are slidably connected in the sliding groove 14 and the arc groove 15. One end of the connecting rod 17 is fixedly connected to the lower surface of the sliding block 18, and the other end of the connecting rod 17 is fixedly connected to the upper surface of the pressing column 16. Because the sliding grooves 14 and the arc grooves 15 are distributed in a staggered manner, the protruding blocks 19 can alternately slide in the sliding grooves 14 and the arc grooves 15 to drive the sliding blocks 18 to move up and down, and further drive the pressing columns 16 to move up and down.

During operation, place the test tube inside inserting a section of thick bamboo 3, start electric putter 9, electric putter 9 drive through diaphragm 8 and insert a section of thick bamboo 3 and upwards remove, and the pressure post 16 inserts inside inserting a section of thick bamboo 3, extrudees fixedly from the test tube top, improves the stability of separation. And the motor 26 is started, the motor 26 rotates to drive the chassis 11 to rotate, and then the cartridge 3 and the test tube inside are driven to rotate, so that the reagent is separated. Because the sliding grooves 14 and the arc grooves 15 on the top ring 12 are distributed in a staggered manner, the convex blocks 19 can alternately slide in the sliding grooves 14 and the arc grooves 15 to drive the sliding blocks 18 to move up and down, further drive the pressing columns 16 to move up and down, and cooperate with the buffer assembly to enable the test tube to move up and down, the test tube can also move up and down in the rotating and separating process, and the separation efficiency of the nano magnetic beads is improved.

The first step, the motor 26 rotates to drive the chassis 11 to rotate, so as to drive the insertion cylinder 3 and the test tube inside to rotate, and the motion track is a circle to separate the nano magnetic beads inside the reagent; in the second step, the protruding blocks 19 alternately slide in the sliding grooves 14 and the arc grooves 15 to drive the sliding blocks 18 to move up and down, further drive the pressing columns 16 to move up and down, and cooperate with the buffer assembly to enable the test tube to move up and down, wherein the motion track is a wavy line, so that the separation efficiency is further improved. The matching of the two moving tracks makes the nanometer magnetic beads more easily absorbed by the magnetic source at the periphery of the test tube, thereby improving the analysis efficiency.

The bottom of the insertion barrel 3 is provided with a round groove 7, the inside of the round groove 7 is connected with a round rod 10 in a sliding mode, the upper surface of the bottom plate 2 is fixedly connected with a motor 26, a driving shaft of the motor 26 is fixedly connected with a chassis 11, and the bottom of the round rod 10 is fixedly connected to the chassis 11. The motor 26 rotates to drive the chassis 11 to rotate, so as to drive the cartridge 3 and the test tube inside to rotate, and separate the nano magnetic beads in the reagent.

In order to enable the pressing column 16 to be inserted into the inserting cylinder 3 to extrude and fix the test tube, a transverse plate 8 is fixedly connected to the outside of the inserting cylinder 3, an electric push rod 9 is fixedly connected to the lower surface of the transverse plate 8, and one end, away from the transverse plate 8, of the electric push rod 9 is fixedly connected to the chassis 11. When the pressing column 16 is positioned above the inserting cylinder 3, the electric push rod 9 drives the inserting cylinder 3 to move upwards through the transverse plate 8, and the pressing column 16 is inserted into the inserting cylinder 3.

In order to observe the separation condition inside the test tube, an observation port 4 is formed in the wall body of the insertion tube 3.

The top of chassis 11 is provided with top ring 12, and top ring 12 and chassis 11 correspond to and distribute, and the annular groove 13 has been seted up to the lower surface of top ring 12, has all seted up multiunit spout 14 and arc groove 15 on the both sides inner wall of annular groove 13, and spout 14 and arc groove 15 staggered distribution, spout 14 and arc groove 15 intercommunication. The sliding grooves 14 and the arc grooves 15 are distributed in a staggered manner, and the protruding blocks 19 can alternately slide in the sliding grooves 14 and the arc grooves 15 to drive the sliding blocks 18 to move up and down.

In order to prevent damage to the test tube extrusion, the lower surface of the press column 16 is fixedly connected with a second rubber pad 21, and the upper surface of the slide plate 25 is fixedly connected with a first rubber pad 20.

The upper surface fixedly connected with gallows 24 of bottom plate 2, the lower surface fixedly connected with hydraulic pressure pole 23 at gallows 24 top, the bottom fixedly connected with fixed plate 22 of hydraulic pressure pole 23, fixed plate 22 fixed connection is on the inner circle of top ring 12. The expansion and contraction of the expansion and contraction end of the hydraulic rod 23 controls the up-and-down movement of the top ring 12.

Claims

1. The utility model provides a novel two high-efficient chemiluminescence analyzer of two separation, includes analyzer body (1), its characterized in that: the top fixedly connected with bottom plate (2) of analysis appearance body (1), the top of bottom plate (2) is provided with inserts a section of thick bamboo (3), insert a section of thick bamboo (3) bottom and be provided with buffer assembly, buffer assembly includes extensible member (5), spring (6) and slide (25), slide (25) sliding connection is in the inside of inserting a section of thick bamboo (3), the one end fixed connection of extensible member (5) is inserting a section of thick bamboo (3) bottom, the other end fixed connection of extensible member (5) is in the lower surface of slide (25), the outside at extensible member (5) of spring (6) suit, the one end fixed connection of spring (6) is in inserting a section of thick bamboo (3) bottom, the other end fixed connection of spring (6) is in the lower surface of slide (25), the top of inserting a section of thick bamboo (3) is provided with extrusion subassembly.

2. The novel two-step two-separation high-efficiency chemiluminescent analyzer of claim 1 wherein: the novel socket is characterized in that a round groove (7) is formed in the bottom of the socket body (3), a round rod (10) is connected to the inside of the round groove (7) in a sliding mode, a motor (26) is fixedly connected to the upper surface of the bottom plate (2), a chassis (11) is fixedly connected to the driving shaft of the motor (26), and the bottom of the round rod (10) is fixedly connected to the chassis (11).

3. The novel two-step two-separation high-efficiency chemiluminescent analyzer of claim 2 wherein: the novel electric socket is characterized in that a transverse plate (8) is fixedly connected to the outside of the socket body (3), an electric push rod (9) is fixedly connected to the lower surface of the transverse plate (8), and one end, away from the transverse plate (8), of the electric push rod (9) is fixedly connected to a chassis (11).

4. A novel two-step, two-separation, high-efficiency chemiluminescent analyzer of claim 3 wherein: an observation port (4) is formed in the wall body of the insertion barrel (3).

5. The novel two-step two-separation high-efficiency chemiluminescent analyzer of claim 2 wherein: the top of chassis (11) is provided with top ring (12), top ring (12) and chassis (11) correspond and distribute, annular groove (13) have been seted up to the lower surface of top ring (12), multiunit spout (14) and arc groove (15) have all been seted up on the both sides inner wall of annular groove (13), spout (14) and arc groove (15) crisscross distribution, spout (14) and arc groove (15) intercommunication.

6. The novel two-step two-separation high-efficiency chemiluminescent analyzer of claim 5 wherein: the extrusion assembly comprises a pressing column (16), a connecting rod (17), a sliding block (18) and a protruding block (19), wherein the protruding block (19) is arranged into two groups, the two groups of protruding blocks (19) are respectively and fixedly connected to two ends of the sliding block (18), the protruding block (19) is slidably connected in a sliding groove (14) and an arc groove (15), one end of the connecting rod (17) is fixedly connected to the lower surface of the sliding block (18), and the other end of the connecting rod (17) is fixedly connected to the upper surface of the pressing column (16).

7. The novel two-step two-separation high-efficiency chemiluminescent analyzer of claim 6 wherein: the lower surface of the pressing column (16) is fixedly connected with a second rubber pad (21), and the upper surface of the sliding plate (25) is fixedly connected with a first rubber pad (20).

8. The novel two-step two-separation high-efficiency chemiluminescent analyzer of claim 5 wherein: the lifting frame is characterized in that a lifting frame (24) is fixedly connected to the upper surface of the bottom plate (2), a hydraulic rod (23) is fixedly connected to the lower surface of the top of the lifting frame (24), a fixing plate (22) is fixedly connected to the bottom of the hydraulic rod (23), and the fixing plate (22) is fixedly connected to the inner ring of the top ring (12).