CN2194001Y - Gradient test paper for antibiotic sensitization test - Google Patents
Gradient test paper for antibiotic sensitization test Download PDFInfo
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- CN2194001Y CN2194001Y CN 93245821 CN93245821U CN2194001Y CN 2194001 Y CN2194001 Y CN 2194001Y CN 93245821 CN93245821 CN 93245821 CN 93245821 U CN93245821 U CN 93245821U CN 2194001 Y CN2194001 Y CN 2194001Y
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- test paper
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
The utility model relates to a gradient test paper for antibiotic sensitization tests, which is characterized in that the utility model is composed of a terylene sheet and 15 tablets containing different concentrations; the tablets are attached on the terylene sheet by a pressure-sensitive adhesive according to the magnitude orders of the concentrations; the thickness of the test paper is 0.2-0.6MM. The minimum bacteria inhibiting concentration can be read out directly, and the utility model provides an available reference in medication dosage range for clinical reports; the clinician can effectively select antibiotic, as well as can determine reasonable medication dosage.
Description
The utility model belongs to medical antibiotic sensitivity test gradient test paper.
At present, in the U.S., continue to use the methods such as agar dilution of agar diffusion method, meat soup microdilution and improvement that standard committee of American National clinical labororatory recommends for the antibiotic sensitivity test of individual patient sample isolated strains clinically always.Other countries and China are also basic identical.Clinically, infection serious, refractory often makes doctors' anxious seat, feels simply helpless.Used agar dilution is only used a kind of test paper of concentration, comparatively limits to, and quantity of information is less.To a plurality of antibiotic sensitive, sensitivity how on earth, and is not fully aware of such as report.The clinician does not have sensitization test to instruct, and takes turns to use microbiotic instead with the no specific aim in end, the end not know how much dose this be advisable with.These all are unfavorable for rationally using microbiotic, and dosage has been used little can not effectively kill or suppress pathogen, and dosage has been used big may increase patient's payment for medical care burden, and may produce bad reaction.The agar dilution of improvement is accurate inadequately to the big class microbiotic with a lactams structure; And many anaerobions undergrowth often in the meat soup medium.
The purpose of this utility model is to provide a kind of antibiotic sensitivity test gradient test paper, and it can directly read minimum inhibitory concentration, to clinical report can be for reference the dosage scope.
Antibiotic sensitivity test gradient test paper of the present utility model is characterized in that it is made of polyester flake and 15 tablets that contain variable concentrations, and tablet is attached on the polyester flake with pressure-sensitive adhesive by the size order of concentration, and the thickness of test paper is 0.2-0.6mm.
Above-mentioned antibiotic sensitivity test gradient test paper, the concentration value of 15 scraps of paper is 0.031,0.0625,0.125,0.25,0.5,1,2,4,8,16,32,64,128,256,512.
Antibiotic sensitivity test gradient test paper, its scraps of paper contain concentration can also be 0.125,0.25,0.5,1,2,4,8,16,32,64,128,256,512,1024,2048.
The thick 0.2mm that is preferably of the paper of antibiotic sensitivity test gradient test paper.
Fig. 1, structural representation of the present utility model.Wherein, 1 polyester flake, the 2 pastille scraps of paper.
Fig. 2, the left view of Fig. 1.
Fig. 3, the right view of Fig. 1.
Fig. 4, inhibition zone synoptic diagram of the present utility model.
Fig. 5, same thalline different antibiotic fungistatic effect synoptic diagram.
Our antibiotic sensitivity test gradient test paper as shown in Figure 1, as carrier, a plurality of different test-papers of concentration that contain are attached on the polyester flake with pressure-sensitive adhesive by the concentration order by a slice polyester flake, the polyester flake another side indicates the concentration value of each scraps of paper.Referring to Fig. 2, Fig. 3.
During use, only need medicine carrying is simultaneously sticked on agar medium, behind the incubation certain hour, just can produce an antibacterial territory, this territory is a cone shape, and the concentration that the tip meets on the test paper is minimum inhibitory concentration.Referring to Fig. 4.From test paper gradient concentration scale, can directly read minimum inhibitory concentration, come into plain view, need not calculate.According to minimum inhibitory concentration just can to clinical report can be for reference the dosage scope.Fig. 5, be ceftriaxone, amikacin, Xi Lixin, cephazolin, gentamicin and six kinds of antibiotic fungistatic effect figure of chloromycetin on same morganella morganii, the fungistatic effect of ceftriaxone, amikacin is best as seen from the figure, and various antibiotic fungistatic effects have distinct comparison.
Terylene film (principal ingredient is the poly terephthalic acid diethylester), thickness 0.05-0.17mm, thickness does not have any influence to sensitization test, is advisable with 0.1mm.
Filter paper thickness is influential to sensitization test, is generally 0.2-0.6mm, and is the most responsive with 0.2.
Pressure sensitive adhesive (principal ingredient is a polyacrylate) can have multiple choices, such as PS-3, and PS-10, PS-9317, YH-710, BCY-401, DNT-01, KP etc.
Microbiotic meets bulk drug or injection injection that Chinese Pharmacopoeia is stipulated.
The whole pressure sterilizings of the used utensil of preparation process.
The preparation of antibiotic sensitivity test gradient test paper:
1 prints microbiotic symbol, gradient scale to the terylene film
2 filter paper cut into the wide slice of 2.5mm
The antibiotic solution of 3 preparation variable concentrations
4 with filter paper bar proofing variable concentrations soup and drying respectively
5 terylene film gluings
The 6 filter paper bars that will soak medicine are pasted on by the gradient order that (concentration of medicinal chart bar must match with the concentration of mark on the film on the film
7 tailor into wall scroll and the packing of 5 * 50mm.
Above-mentioned 3-7 must finish under aseptic condition.
The drug solution preparation:
At present, we select clinical ten kinds of microbiotic commonly used: benzyl penicillin, erythromycin, chloromycetin, ampicillin, gentamicin sulphate, amikacin sulfate, cephazolin, Xi Lixin, ceftriaxone, Cefotaxime.As required, kind can enlarge at any time.
Claims (4)
1, antibiotic sensitivity test gradient test paper is characterized in that it is made of polyester flake and 15 tablets that contain variable concentrations, and tablet is attached on the polyester flake with pressure-sensitive adhesive by the size order of concentration, and the thickness of test paper is 0.2-0.6mm.
2, antibiotic sensitivity test gradient test paper as claimed in claim 1, the concentration value that it is characterized in that 15 scraps of paper is 0.031,0.0625,0.125,0.25,0.5,1,2,4,8,16,32,64,128,256,512.
3, antibiotic sensitivity test gradient test paper as claimed in claim 1 is characterized in that it is 0.125,0.25,0.5,1,2,4,8,16,32,64,128,256,512,1024,2048 that the scraps of paper contain concentration.
4, antibiotic sensitivity test gradient test paper as claimed in claim 1 is characterized in that the paper of test paper is thick and is 0.2mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93245821 CN2194001Y (en) | 1993-11-24 | 1993-11-24 | Gradient test paper for antibiotic sensitization test |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93245821 CN2194001Y (en) | 1993-11-24 | 1993-11-24 | Gradient test paper for antibiotic sensitization test |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2194001Y true CN2194001Y (en) | 1995-04-05 |
Family
ID=33818662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 93245821 Expired - Fee Related CN2194001Y (en) | 1993-11-24 | 1993-11-24 | Gradient test paper for antibiotic sensitization test |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2194001Y (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100414298C (en) * | 2004-03-08 | 2008-08-27 | 朱建军 | Stepped concentration gradient detecting bar and preparing process thereof |
| CN110016494A (en) * | 2019-04-24 | 2019-07-16 | 张敏 | A kind of haemophilus drug sensitivity testing in vitro detector bar |
-
1993
- 1993-11-24 CN CN 93245821 patent/CN2194001Y/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100414298C (en) * | 2004-03-08 | 2008-08-27 | 朱建军 | Stepped concentration gradient detecting bar and preparing process thereof |
| CN110016494A (en) * | 2019-04-24 | 2019-07-16 | 张敏 | A kind of haemophilus drug sensitivity testing in vitro detector bar |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |