CN219397760U - 组合式补骨片及补骨片单元 - Google Patents

组合式补骨片及补骨片单元 Download PDF

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CN219397760U
CN219397760U CN202223022872.7U CN202223022872U CN219397760U CN 219397760 U CN219397760 U CN 219397760U CN 202223022872 U CN202223022872 U CN 202223022872U CN 219397760 U CN219397760 U CN 219397760U
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bone
plate body
sheet unit
bone supplementing
drug
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蔡栋国
黄胤中
洪国盛
沈永康
欧耿良
欧雨欣
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Yujie Co ltd
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Yujie Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A61B17/8085—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates with pliable or malleable elements or having a mesh-like structure, e.g. small strips
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    • A61B17/688—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin for reattaching pieces of the skull
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  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Prostheses (AREA)
  • Surgical Instruments (AREA)

Abstract

本实用新型是一种补骨片单元及组合式补骨片。补骨片单元为一板体，板体包含有相对两侧面及一外环壁面，外环壁面连接于两侧面的间；板体上沿着外环壁面成形有多个结合柱及多个结合槽，结合柱的形状及结合槽的形状相对应；补骨片单元内部形成有多个药物空腔，且补骨片单元上形成有多个药物释放开口，药物释放开口连通于药物空腔。借由药物空腔以及药物释放开口，补骨片单元能够在手术后通过缓慢释放药物来促进伤口愈合。借由以许多小块的补骨片单元组合并且弯折成所需形状的大块组合式补骨片，避免对昂贵的医疗材料进行切削造成的材料浪费。

Description

组合式补骨片及补骨片单元
技术领域
本实用新型是涉及一种医疗植入物，尤指一种可用于修补颅骨缺损的组合式补骨片及补骨片单元。
背景技术
当病患因外伤或脑科手术等原因而移除大面积的颅骨后，需在后续的治疗中对颅骨缺损部位的进行修补成形，以避免脆弱的脑组织因缺乏骨骼保护而出现后遗症；现有技术的颅骨修补成形是先以切削成形的方式，将整块金属或高分子材料切削制作成形状与缺损部位相吻合的补骨片，然后再将成形的补骨片通过手术固定至颅骨。
然而，因颅骨的形状为曲面，因此使用整块材料进行切削加工时往往会需要切除大量的材料，因此现有技术的补骨片不但浪费材料，同时也需耗费大量时间制作。
因此，现有技术的补骨片实有待加以改良。
实用新型内容
有鉴于前述的现有技术的缺点及不足，本实用新型提供一种补骨片以节省材料及制作时间。
为达到上述目的，本实用新型所采用的技术手段为设计一种补骨片单元，其为一板体，该板体包含有相对两侧面及一外环壁面，该外环壁面连接于该两侧面之间；该板体上沿着该外环壁面成形有多个结合柱及多个结合槽，该多个结合柱的形状及该多个结合槽的形状相对应；该补骨片单元内部形成有多个药物空腔，且该补骨片单元上形成有多个药物释放开口，所述药物释放开口连通于所述药物空腔。
为达到上述目的，本实用新型所采用的技术手段为设计一种补骨片单元，其为一板体，该板体包含有相对两侧面及一外环壁面，该外环壁面连接于该两侧面之间；该板体上沿着该外环壁面成形有多个结合柱；该补骨片单元内部形成有多个药物空腔，且该补骨片单元上形成有多个药物释放开口，所述药物释放开口分别连通于所述药物空腔。
为达到上述目的，本实用新型所采用的技术手段为设计一种补骨片单元，其为一板体，该板体包含有相对两侧面及一外环壁面，该外环壁面连接于该两侧面之间；该板体上沿着该外环壁面成形有多个结合槽；该补骨片单元内部形成有多个药物空腔，且该补骨片单元上形成有多个药物释放开口，所述药物释放开口分别连通于所述药物空腔。
进一步而言，所述的补骨片单元，其中各该药物空腔的最大截面积大于相对应的该药物释放开口的最大截面积；各该药物空腔中具有该最大截面积的截面的法线方向平行于相对应的该药物释放开口的一开口方向。
进一步而言，所述的补骨片单元，其中该补骨片单元包含多个药物释放通道，所述药物释放通道分别连通于所述药物释放开口与所述药物空腔。
进一步而言，所述的补骨片单元，其中各该药物空腔在其纵向截面上的形状为圆形、椭圆形、卵形或三角形；各该药物空腔的该纵向截面的法线方向平行于相对应的该药物释放开口的一开口方向。
进一步而言，所述的补骨片单元，其中各该药物空腔的截面积随着截面远离相对应的该药物释放开口而增加；该截面的法线方向平行于相对应的该药物释放开口的一开口方向。
进一步而言，所述的补骨片单元，其中该多个结合柱及该多个结合槽成形于该板体的该外环壁面上。
进一步而言，所述的补骨片单元，其中该板体为N边形而使该外环壁面成形有N个连接面；该结合柱的数量为N个，其分别成形于该N个连接面；该结合槽的数量为N个，其分别成形于该N个连接面；其中，N>2，且N为整数。
进一步而言，所述的补骨片单元，其中该多个结合柱成形于该板体的其中一该侧面上；该多个结合槽贯穿该补骨片单元的该两侧面。
进一步而言，所述的补骨片单元，其中该多个结合柱分别成形于该板体的该两侧面上；该多个结合槽贯穿该补骨片单元的该两侧面。
进一步而言，所述的补骨片单元，其中该板体贯穿该两侧面成形有多个螺丝孔，且该多个螺丝孔沿着该板体的该外环壁面排列。
进一步而言，所述的补骨片单元，其中该板体为多边形而使该外环壁面具有多个角部，各该结合柱及各该结合槽邻近于其中一该角部。
进一步而言，所述的补骨片单元，其中该板体为N边形而使该外环壁面成形有N个连接面；该结合柱的数量及该结合槽的数量共为N个；其中，N>2，且N为整数。
进一步而言，所述的补骨片单元，其中该补骨片单元的厚度小于1mm。
进一步而言，所述的补骨片单元，其中该补骨片单元的材料包含钛、钛六铝四钒合金、316L不锈钢、聚醚醚酮、或铝。
进一步而言，所述的补骨片单元，其中该板体具有多个药物插销形成于其中一该侧面，各该药物插销内形成有其中一该药物空腔，且各该药物插销的末端形成有其中一该药物释放开口，该其中一药物释放开口连通于该其中一药物空腔。
为达到上述目的，本实用新型所采用的技术手段为设计一种组合式补骨片，其为一能弯折的板体，该组合式补骨片包含多个前述的补骨片单元，所述补骨片单元相互连接；任两相互连接的该补骨片单元中，其中一该补骨片单元的至少一该结合柱穿设于另一该补骨片单元的至少一该结合槽内。
本实用新型的优点在于，借由设计一种形状为板状的补骨片单元，各补骨片单元沿着其外环壁面成形有多个结合柱及多个结合槽，补骨片单元能够以边缘的结合柱及结合槽相互连接而组合形成大块的组合式补骨片；在为病患破损的颅骨制作补骨片时，本实用新型能够以许多小块的补骨片单元组合并且弯折成与颅骨缺损部位的形状相吻合的大块组合式补骨片，借此可避免对昂贵的医疗材料进行切削加工造成的材料浪费，并且也可节省制造时间。
此外，借由药物空腔以及药物释放开口，补骨片单元能够在手术后通过缓慢释放药物来促进伤口愈合。精确来说，可以在手术前将药物填充到药物腔内，然后将骨板单元放入人体内后，药物会通过药物释放口缓慢释放。
附图说明
图1是本实用新型的补骨片单元的第一实施例的立体外观图。
图2是本实用新型的补骨片单元的第一实施例的上视示意图。
图3是本实用新型的补骨片单元的第一实施例的纵向剖面局部放大图。
图4至图8是本实用新型的补骨片单元的其他实施例的纵向剖面局部放大图。
图9是本实用新型的补骨片单元的第二实施例的立体外观图。
图10是本实用新型的补骨片单元的第三实施例的立体外观图。
图11是本实用新型的补骨片单元的第四实施例的立体外观图。
图12是本实用新型的补骨片单元的第五实施例的立体外观图。
图13是本实用新型的补骨片单元的第六实施例的立体外观图。
图14是本实用新型的补骨片单元的第七实施例的立体外观图。
图15是本实用新型的补骨片单元的第七实施例的纵向剖面图。
图16是本实用新型的组合式补骨片的第一实施例的立体外观图。
图17是本实用新型的补骨片单元的第八实施例的立体外观图。
图18是本实用新型的补骨片单元的第八实施例的另一立体外观图。
图19是本实用新型的补骨片单元的第九实施例的立体外观图。
图20是本实用新型的补骨片单元的第九实施例的另一立体外观图。
图21是本实用新型的组合式补骨片的第二实施例的立体外观图。
具体实施方式
以下配合图式及本实用新型的较佳实施例，进一步阐述本实用新型为达成预定实用新型目的所采取的技术手段。
请参阅图1至图3所示，本实用新型的补骨片单元包含一板体、多个结合柱30、多个结合槽40、多个药物空腔50及多个药物释放开口60。板体包含有相对两侧面10及一外环壁面20，外环壁面20连接于两侧面10之间。
板体上沿着外环壁面20成形有多个结合柱30及多个结合槽40，结合柱30的形状及结合槽40的形状相对应，借此两个本实用新型的补骨片单元可以借由将结合柱30与结合槽40相互嵌合予以组装。
药物空腔50(如图3所示)形成于补骨片单元内部。药物释放开口60形成于补骨片单元上，且连通于药物空腔50，借此药物可以在手术前预先填充到药物腔50中，然后在补骨片单元放入人体内后，药物腔50中的药物会慢慢释放出来。
在较佳实施例中，药物空腔50形成在板体和结合柱30的内部；药物释放开口60形成于两侧面10、外环壁面20以及结合柱30的所有外表面。换言之，药物释放开口60和药物空腔50设置在补骨片单元的所有外表面上。在另一较佳实施例中，药物释放开口60和药物空腔50仅设置在板体上。较佳地，药物空腔50和药物释放开口60通过蚀刻制程一起形成。
此外，较佳地，补骨片单元具有多个药物释放通道70。所述药物释放通道70连通所述药物释放开口60和所述药物空腔50。换言之，药物释放开口60和药物空腔50通过药物释放通道70连接。在另一个较佳实施例中，省略了药物释放通道70，药物释放开口60和药物空腔50是直接相连的。
请参考图3至图8，药物空腔50的详细尺寸及形状以药物空腔50的剖面及纵剖面作进一步说明。各药物空腔50的剖面法线方向平行于对应的药物释放开口60的开口方向，而各药物空腔50的纵向截面的法线方向垂直于对应的药物释放开口60的开口方向。
在较佳实施例中，各药物空腔50的最大截面积大于对应的药物释放开口60的最大截面积，从而使药物空腔50中的药物能够缓慢地被释放以使药物释放的时间更长。药物空腔50的纵向截面形状可为圆形(如图3和图4所示)、椭圆形(如图5和图6所示)或卵形。
请参考图7及图8，在另一个较佳实施例中，各药物空腔50的横截面的面积随着横截面X-X远离相应的药物释放开口60移动而增加。在该特定实施例中，各药物空腔50在纵向截面上的形状较佳为三角形。
请参考图1及图2，较佳地，前述的多个结合柱30及多个结合槽40在本实施例中成形于板体的外环壁面20上，借此，多个补骨单元通过外环壁面20的结合柱30及结合槽40相连结合成为一补骨片组件后，该补骨片组件的表面不会出现明显的高低落差(如图21)，但多个结合柱及多个结合槽的位置不以此为限，仅要多个结合柱及多个结合槽沿着板体的外环壁面成形即可，所谓的沿着板体的外环壁面成形，不以成形在外环壁面为限，只要是沿着外环壁面的位置环绕延伸或排列即可，也就是说，多个结合柱及多个结合槽可以如本实施例成形于外环壁面20上(如图1)，或者也可以如同本实用新型的第七实施例(如图17)，多个结合柱30F及多个结合槽40F沿板体的侧面10F邻近外环壁面20F的边缘处成形。
前述的板体在本实施例中当板体为N边形时(其中，N>2，且N为整数，即N是大于2的整数)，外环壁面成形有N个连接面；结合柱的数量为N个，其分别成形于N个连接面；结合槽的数量为N个，其分别成形于N个连接面，简单来说，当板体为多边形时，多边形的每一个连接面都具有一结合柱及一结合槽；具体来说，本实施例中的N等于六，也就是说，本实施例的板体为正六边形而使外环壁面20成形有六个连接面21；结合柱30的数量为六个，其分别成形于六个连接面21；结合槽40的数量为六个，其分别成形于六个连接面21，但多边形板体的各连接面的结合柱及结合槽的数量不以此为限，例如在本实用新型的第二实施例中(如图9)，部份的连接面21A具有二结合柱30A但没有结合槽，部份的连接面21A则是具有二结合槽40A但没有结合柱，如此也可。
前述的结合柱30的形状在本实施例中为圆柱状，结合槽40的形状则对应结合柱30是圆形凹槽，但结合柱的形状也可以视情况而形成四角柱状的结合柱30B(如图11)，或三角柱状的结合柱30C(如图12)，或五角柱状的结合柱30D(如图13)等各种不同形状的柱体，并且结合槽也可以对应各种结合柱而成为方形的结合槽40B(如图11)、三角形的结合槽40C(如图12)或五角形的结合槽40D(如图13)等各种不同形状的凹槽。
在其他较佳的实施例中，结合柱30E(如图10)的顶端连接有一圆形的结合珠50E，且结合珠50E的宽度大于结合柱30E的宽度，结合槽40E的凹槽底部则连接成形有一圆形的结合珠槽60E，且结合珠槽60E的宽度对应结合珠50E的宽度，借此，在连接不同的补骨片单元时，可借由压迫的方式使结合珠50E压迫结合槽40E并使结合槽40E弹性地变形扩张，进而使结合珠50E贯穿结合槽40E并卡合于结合珠槽60E内，借此强化结合力以避免补骨片单元在结合后容易被拔脱分离。
请参阅图14及15所示，本实用新型的补骨片单元的第七实施例的具体结构大致与第一实施例相同，其差别在于，在第七实施例中具有多个药物插销80H形成于板体的其中一侧面10H上。每一个药物插销80H内形成有其中一个药物空腔50H，且每一个药物插销80H的末端形成有其中一个药物释放开口60H，每一个药物插销80H上的药物释放开口60H及药物空腔50H相连通。药物插销80H较佳为通过特殊化学工序形成的微管，且较佳是密集地排列在侧面10H上。
请参阅图16所示，本实用新型的组合式补骨片为一能弯折的板体，组合式补骨片包含多个补骨片单元P，多个补骨片单元P相互连接；任两相互连接的补骨片单元P中，其中一补骨片单元P的至少一结合柱30穿设于另一补骨片单元P的至少一结合槽40内；在本实施例中，补骨片单元P是通过位于板体的外环壁面20的结合柱30与结合槽40穿设连接形成组合式补骨单元，且具体来说，组合式补骨片单元是由多个第一实施例的补骨片单元P连接形成，但不以此为限，组合式补骨片也可以是由多个前述其他实施例的补骨单元连接形成。
请参阅图17及图18所示，本实用新型的补骨片单元的第八实施例与第一实施例大致相同，差异在于多个结合柱30F与多个结合槽40F的成形位置。
多个结合柱30F成形于补骨片单元的板体的其中一侧面10F上；多个结合槽40F贯穿补骨片单元的两侧面；在本实施例中，板体贯穿两侧面10F成形有多个螺丝孔11F，且多个螺丝孔11F沿着板体的外环壁面20F排列，但螺丝孔11F贯穿板体两侧面10F的位置不以此为限，甚至板体也可以没有螺丝孔。
在本实施例中，板体为多边形而使其外环壁面20F具有多个角部22F，各结合柱30F及各结合槽40F邻近于其中一角部22F，具体来说，板体为六边形，角部22F位于外环壁面20F的各转折处，结合柱30F及结合槽40F的位置皆邻近于转折处，但结合柱及结合槽的位置不以此为限，例如也可以在设置在邻近于相邻的两角部22F的中央处。
在本实施例中，板体为N边形，其中N>2，且N为整数(N是大于2的整数)，而使外环壁面20F成形有N个连接面；结合柱30F的数量及结合槽40F的数量共为N个，具体来说，N等于六，板体为六边形而使外环壁面20F成形有六个连接面21F；结合柱30F的数量及结合槽40F的数量共为六个，分别为三个结合柱30F及三个结合槽40F，以使多边形板体的各连接面21F能够与相连接的板体稳固地连接，但结合柱的数量及结合槽的数量总合不以此为限，例如也可以在六边形板体中设置共十二个结合柱及结合槽。
请参阅图19及图20所示，本实用新型的补骨片单元的第九实施例与前述的第八实施例大致相同，差别在于多个结合柱30G分别成形于板体的两侧面10G上；因此，板体的多个结合柱可视情况而仅成形于板体的其中一侧面，或位置对称地成形于板体的两侧面(即等同于所有结合柱皆上下贯穿板体)，或位置非对称地成形于板体的两侧面(即等同于部分结合柱上下贯穿板体，部分结合柱成形于板体的一侧面，部分结合柱成形于板体的另一侧面)，以上皆可。
在前述补骨片单元的第八与第九实施例中，板体的两侧面距离定义为板体厚度，板体厚度小于1mm，但补骨片单元的板体厚度不以此为限，仅要当补骨片单元的结合柱及结合槽成形于板体的侧面时，板体能够配合手术的需求进行弯折变形即可。
前述所有补骨片单元的实施例中，板体材质可以是钛、钛六铝四钒合金(Ti-6Al-4V)、聚醚醚酮(polyetheretherketone，PEEK)、316L不锈钢等等生物相容性及机械强度优良的材料中的任何一种，或者补骨片单元的材质也可以是重量较轻且便宜的铝。此外，上述的全部实施例中的补骨片单元皆具有药物空腔50及药物释放通道60，借此释放药物。
请参阅图21所示，本实用新型的组合式补骨片的第二实施例与第一实施例大致相同，差别在于本实施例所使用的补骨片单元的多个结合柱及多个结合槽成形于各板体的侧面，并且因此补骨片单元的间是以边缘上下重叠的方式进行连接；其中，补骨片单元P1对应于本实用新型的补骨片单元的第九实施例(如图19)，补骨片单元P2对应于本实用新型的补骨片单元的第八实施例(如图17)，补骨片单元P3与本实用新型的补骨片单元的第八实施例大致相同，但其中一结合柱P4的高度较其他结合柱高，以便于连接补骨片单元P2。
本实用新型于使用时，将多个小块的补骨片单元相互连接并弯折，形成一片形状对应于颅骨缺损部位的大块的组合式补骨片；当组合式补骨片属于本实用新型的组合式补骨片的第二实施例(如图21)所示的态样时，该组合式补骨片的边缘可重叠覆盖于颅骨表面，并以螺栓贯穿补骨片单元的螺丝孔，并螺合于颅骨的方式将补骨片固定于颅骨上；而当组合式补骨片的形式属于本实用新型的组合式补骨片的第一实施例(如图16)所示的态样时，则视需求对组合式补骨片的边缘进行修整，再将组合式补骨片嵌入颅骨缺损部位，并以其他方式将组合式补骨片固定于颅骨。
以上所述仅是本实用新型的优选实施例而已，并非对本实用新型做任何形式上的限制，虽然本实用新型已以优选实施例揭露如上，然而并非用以限定本实用新型，任何熟悉本专业的技术人员，在不脱离本实用新型技术方案的范围内，当可利用上述揭示的技术内容作出些许更动或修饰为等同变化的等效实施例，但凡是未脱离本实用新型技术方案的内容，依据本实用新型的技术实质对以上实施例所作的任何简单修改、等同变化与修饰，均仍属于本实用新型技术方案的范围内。

Claims (17)

1.一种补骨片单元，其特征在于，其为一板体，该板体包含有相对两侧面及一外环壁面，该外环壁面连接于该两侧面之间；该板体上沿着该外环壁面成形有多个结合柱及多个结合槽，该多个结合柱的形状及该多个结合槽的形状相对应；该补骨片单元内部形成有多个药物空腔，且该补骨片单元上形成有多个药物释放开口，所述药物释放开口连通于所述药物空腔。
2.如权利要求1所述的补骨片单元，其特征在于，各该药物空腔的最大截面积大于相对应的该药物释放开口的最大截面积；各该药物空腔中具有该最大截面积的截面的法线方向平行于相对应的该药物释放开口的一开口方向。
3.如权利要求1所述的补骨片单元，其特征在于，该补骨片单元包含多个药物释放通道，所述药物释放通道分别连通于所述药物释放开口与所述药物空腔。
4.如权利要求1所述的补骨片单元，其特征在于，各该药物空腔在其纵向截面上的形状为圆形、椭圆形、卵形或三角形；各该药物空腔的该纵向截面的法线方向平行于相对应的该药物释放开口的一开口方向。
5.如权利要求1所述的补骨片单元，其特征在于，各该药物空腔的截面积随着截面远离相对应的该药物释放开口而增加；该截面的法线方向平行于相对应的该药物释放开口的一开口方向。
6.如权利要求1至5中任一项所述的补骨片单元，其特征在于，该多个结合柱及该多个结合槽成形于该板体的该外环壁面上。
7.如权利要求6所述的补骨片单元，其特征在于，该板体为N边形而使该外环壁面成形有N个连接面；该结合柱的数量为N个，其分别成形于该N个连接面；该结合槽的数量为N个，其分别成形于该N个连接面；其中，N>2，且N为整数。
8.如权利要求1至5中任一项所述的补骨片单元，其特征在于，该多个结合柱成形于该板体的其中一该侧面上；该多个结合槽贯穿该补骨片单元的该两侧面。
9.如权利要求1至5中任一项所述的补骨片单元，其特征在于，该多个结合柱分别成形于该板体的该两侧面上；该多个结合槽贯穿该补骨片单元的该两侧面。
10.如权利要求8所述的补骨片单元，其特征在于，该板体贯穿该两侧面成形有多个螺丝孔，且该多个螺丝孔沿着该板体的该外环壁面排列。
11.如权利要求1至5中任一项所述的补骨片单元，其特征在于，该板体为多边形而使该外环壁面具有多个角部，各该结合柱及各该结合槽邻近于其中一该角部。
12.如权利要求1至5中任一项所述的补骨片单元，其特征在于，该板体为N边形而使该外环壁面成形有N个连接面；该结合柱的数量及该结合槽的数量共为N个；其中，N>2，且N为整数。
13.如权利要求8所述的补骨片单元，其特征在于，该补骨片单元的厚度小于1mm。
14.如权利要求1至5中任一项所述的补骨片单元，其特征在于，该板体具有多个药物插销形成于其中一该侧面，各该药物插销内形成有其中一该药物空腔，且各该药物插销的末端形成有其中一该药物释放开口，该其中一药物释放开口连通于该其中一药物空腔。
15.一种组合式补骨片，其特征在于，其为一能弯折的板体，该组合式补骨片包含多个如权利要求1至14中任一项所述的补骨片单元，所述补骨片单元相互连接；任两相互连接的该补骨片单元中，其中一该补骨片单元的至少一该结合柱穿设于另一该补骨片单元的至少一该结合槽内。
16.一种补骨片单元，其特征在于，其为一板体，该板体包含有相对两侧面及一外环壁面，该外环壁面连接于该两侧面之间；该板体上沿着该外环壁面成形有多个结合柱；该补骨片单元内部形成有多个药物空腔，且该补骨片单元上形成有多个药物释放开口，所述药物释放开口分别连通于所述药物空腔。
17.一种补骨片单元，其特征在于，其为一板体，该板体包含有相对两侧面及一外环壁面，该外环壁面连接于该两侧面之间；该板体上沿着该外环壁面成形有多个结合槽；该补骨片单元内部形成有多个药物空腔，且该补骨片单元上形成有多个药物释放开口，所述药物释放开口分别连通于所述药物空腔。
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