CN219376125U - Device for continuously extracting ginkgolic acid by carbon dioxide - Google Patents
Device for continuously extracting ginkgolic acid by carbon dioxide Download PDFInfo
- Publication number
- CN219376125U CN219376125U CN202320527142.8U CN202320527142U CN219376125U CN 219376125 U CN219376125 U CN 219376125U CN 202320527142 U CN202320527142 U CN 202320527142U CN 219376125 U CN219376125 U CN 219376125U
- Authority
- CN
- China
- Prior art keywords
- supercritical
- extraction
- storage tank
- ginkgolic acid
- ginkgo leaf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- YXHVCZZLWZYHSA-UHFFFAOYSA-N (Z)-6-[8-pentadecenyl]salicylic acid Natural products CCCCCCC=CCCCCCCCC1=CC=CC(O)=C1C(O)=O YXHVCZZLWZYHSA-UHFFFAOYSA-N 0.000 title claims abstract description 60
- YXHVCZZLWZYHSA-FPLPWBNLSA-N Ginkgoic acid Chemical compound CCCCCC\C=C/CCCCCCCC1=CC=CC(O)=C1C(O)=O YXHVCZZLWZYHSA-FPLPWBNLSA-N 0.000 title claims abstract description 60
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 title claims abstract description 24
- 229910002092 carbon dioxide Inorganic materials 0.000 title claims abstract description 12
- 239000001569 carbon dioxide Substances 0.000 title claims abstract description 12
- 238000000605 extraction Methods 0.000 claims abstract description 63
- 235000011201 Ginkgo Nutrition 0.000 claims abstract description 39
- 241000218628 Ginkgo Species 0.000 claims abstract description 39
- 235000008100 Ginkgo biloba Nutrition 0.000 claims abstract description 39
- 239000000287 crude extract Substances 0.000 claims abstract description 25
- 238000000746 purification Methods 0.000 claims abstract description 24
- 239000013543 active substance Substances 0.000 claims abstract description 14
- 238000006073 displacement reaction Methods 0.000 claims abstract description 9
- 239000000126 substance Substances 0.000 claims abstract description 9
- 239000012530 fluid Substances 0.000 claims description 34
- 238000000926 separation method Methods 0.000 claims description 21
- 239000000463 material Substances 0.000 claims description 10
- 238000004508 fractional distillation Methods 0.000 claims description 9
- 230000004888 barrier function Effects 0.000 claims description 4
- 239000011149 active material Substances 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims 1
- 150000007513 acids Chemical class 0.000 claims 1
- 239000000284 extract Substances 0.000 abstract description 7
- 238000004108 freeze drying Methods 0.000 abstract description 3
- 238000000034 method Methods 0.000 description 8
- 239000009429 Ginkgo biloba extract Substances 0.000 description 4
- 229930003935 flavonoid Natural products 0.000 description 4
- 150000002215 flavonoids Chemical class 0.000 description 4
- 235000017173 flavonoids Nutrition 0.000 description 4
- -1 hydrocarbon phenolic acid Chemical class 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 238000000194 supercritical-fluid extraction Methods 0.000 description 3
- 235000007586 terpenes Nutrition 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 239000012043 crude product Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 238000010298 pulverizing process Methods 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000005194 fractionation Methods 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 238000002414 normal-phase solid-phase extraction Methods 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 238000004064 recycling Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000003815 supercritical carbon dioxide extraction Methods 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids
Landscapes
- Extraction Or Liquid Replacement (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The utility model discloses a device for continuously extracting ginkgolic acid by carbon dioxide, which comprises a supercritical continuous extraction part, a ginkgolic acid purification part and a continuous purification part for extracting residual substances, wherein the supercritical continuous extraction part comprises CO 2 Storage tank, silverApricot leaf crude extract storage tank, supercritical CO 2 Extraction tower, said CO 2 The outer side of the storage tank is provided with a pressure gauge, and the CO 2 The storage tank is connected with the supercritical CO through a pressure gauge 2 The extraction tower is connected, a ginkgo leaf crude extract positive displacement pump is arranged at the outer side of the ginkgo leaf crude extract storage tank, and the ginkgo leaf crude extract storage tank is connected with supercritical CO through the ginkgo leaf crude extract positive displacement pump 2 The extraction towers are connected. Supercritical CO of the utility model 2 The continuous extraction process not only can realize continuous extraction, purification and freeze-drying of ginkgolic acid, but also can realize CO at the same time 2 Is recycled and the other ginkgo leaf active substances in the extract are continuously extracted.
Description
Technical Field
The utility model relates to the technical field of supercritical extraction, in particular to a device for continuously extracting ginkgolic acid by using carbon dioxide.
Background
The ginkgolic acid is a hydrocarbon phenolic acid bioactive substance distributed in ginkgo leaves, ginkgo fruits and the outer seed coats thereof, has the functions of resisting oxidation, inflammation, tumors, allergy, bacteria, preventing and treating diseases and insect pests, and the like, has good application value in food, cosmetics, biological pesticides and medicines, and compared with extraction methods such as solvent, ultrasonic, microwave and even enzymolysis, the supercritical fluid extraction method has better selectivity on ginkgolic acid in extracted solutes, and has the advantages of high extraction efficiency, mild conditions, uneasiness in damaging active ingredients of the extracted matters, and the like, so that the application in the field of extracting active ingredients of Chinese herbal medicines is gradually wide, however, the content of ginkgolic acid in food, medicines and the like is regulated to be less than 10 mug/g by the current quality standard, so that the supercritical fluid extraction process can be used for preferentially realizing high-efficiency recovery of ginkgolic acid in ginkgo leaves, and has very important influence on continuous extraction and purification of flavonoid and terpene lactone active substances in residual materials after the extraction of ginkgolic acid.
In the prior art, patent application CN201410413123 discloses a method for removing and enriching ginkgolic acid from ginkgo leaf extract, and the method adopts a solid phase extraction method based on a molecular imprinting technology to directionally enrich ginkgolic acid, so that the process cost is higher, and the large-scale application is not easy to realize.
Patent application CN201510984822.2 discloses a method for extracting ginkgolic acid by supercritical fluid, which adopts supercritical carbon dioxide fluid extraction deacidification process to extract ginkgolic acid from untreated ginkgolic leaf extract, however, the patent application does not disclose related supercritical equipment suitable for production, and does not provide related information of subsequent extraction and extraction of ginkgolic leaf extract.
Patent application CN201820336352.8 provides a device for removing ginkgolic acid from ginkgo leaves by combining supercritical carbon dioxide extraction and rectification technology, however, the purpose of implementation of the device is only to remove ginkgolic acid from ginkgo leaves, thereby improving the yield and purity of flavonoid extract, and realizing large-scale continuous recovery and purification of ginkgolic acid from ginkgo leaves.
Disclosure of Invention
The utility model aims to provide a device for continuously extracting ginkgolic acid by carbon dioxide, which aims to solve the problems of the background technology.
In order to achieve the above purpose, the present utility model provides the following technical solutions: a device for continuously extracting ginkgolic acid by carbon dioxide comprises a supercritical continuous extraction part, a ginkgolic acid purification part and a continuous purification part for extracting residual substances, wherein the supercritical continuous extraction part comprises CO 2 Storage tank, ginkgo leaf crude extract storage tank and supercritical CO 2 Extraction tower, said CO 2 The outer side of the storage tank is provided with a pressure gauge, and the CO 2 The storage tank is connected with the supercritical CO through a pressure gauge 2 The extraction tower is connected, a ginkgo leaf crude extract positive displacement pump is arranged at the outer side of the ginkgo leaf crude extract storage tank, and the ginkgo leaf crude extract storage tank is connected with supercritical CO through the ginkgo leaf crude extract positive displacement pump 2 The extraction towers are connected;
the ginkgolic acid purifying part comprises a supercritical fluid separating tower, a ginkgolic acid purifying column, a ginkgolic acid freeze dryer and a fluid pressure reducing valve, wherein the supercritical CO 2 The extraction tower is connected with the supercritical fluid separation tower through a fluid pressure reducing valve, an inclined plate type barrier is arranged in the supercritical fluid separation tower, the supercritical fluid separation tower is connected with the ginkgolic acid purification column, and the ginkgolic acid purification column is connected with the ginkgolic acid freeze dryer.
Preferably, the supercritical fluid separation column passes through a pipeThe road is connected with CO 2 Compressor, said CO 2 Compressor and CO 2 The storage tanks are connected.
Preferably, the continuous purification part of the extraction residual substances comprises an extraction residual substance fractional distillation tower and a ginkgo leaf active substance storage tank, wherein the supercritical CO 2 The extraction tower is connected with a rotary pump through a pipeline, the rotary pump is connected with the extraction residual material fractional distillation tower, and the extraction residual material fractional distillation tower is connected with the ginkgo leaf active material storage tank.
Compared with the prior art, the utility model has the beneficial effects that: in the scheme, supercritical CO is adopted 2 The extraction process continuously extracts and purifies ginkgolic acid in ginkgo leaves, and simultaneously realizes CO in supercritical fluid 2 The utility model can continuously extract and purify the effective active substances in ginkgo leaves and realize CO at the same time 2 The reuse of resources, in turn, helps in the achievement of the goals of "carbon peaking" and "carbon neutralization".
Drawings
FIG. 1 is a schematic diagram of the overall apparatus structure of the present utility model.
In the figure: 1. CO 2 A storage tank; 2. a ginkgo leaf crude extract storage tank; 3. supercritical CO 2 An extraction column; 4. a supercritical fluid separation column; 5. a ginkgolic acid purification column; 6. a ginkgolic acid freeze dryer; 7. extracting residual materials from a fractional rectifying tower; 8. a ginkgo leaf active substance storage tank; 9. a pressure gauge; 10. CO 2 A compressor; 11. a positive displacement pump for crude ginkgo leaf extract; 12. a fluid pressure reducing valve; 13. a swash plate type blocker; 14. and (3) rotating the pump.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Example 1
Referring to FIG. 1, the present utility model provides a device for continuously extracting ginkgolic acid with carbon dioxide, which comprises a supercritical continuous extraction part, a ginkgolic acid purification part and a continuous extraction residual substance purification part, wherein the supercritical continuous extraction part comprises CO 2 Storage tank 1, ginkgo leaf crude extract storage tank 2 and supercritical CO 2 Extraction tower 3, CO 2 The outside of the storage tank 1 is provided with a pressure gauge 9 and CO 2 The storage tank 1 is connected with supercritical CO through a pressure gauge 9 2 The extraction tower 3 is connected, a ginkgo leaf crude extract positive displacement pump 11 is arranged at the outer side of the ginkgo leaf crude extract storage tank 2, and the ginkgo leaf crude extract storage tank 2 is connected with supercritical CO through the ginkgo leaf crude extract positive displacement pump 11 2 The extraction towers 3 are connected;
the ginkgolic acid purifying part comprises a supercritical fluid separating tower 4, a ginkgolic acid purifying column 5, a ginkgolic acid freeze dryer 6 and a fluid pressure reducing valve 12, and supercritical CO 2 The extraction tower 3 is connected with the supercritical fluid separation tower 4 through a fluid pressure reducing valve 12, an inclined plate type barrier 13 is arranged in the supercritical fluid separation tower 4, the supercritical fluid separation tower 4 is connected with the ginkgolic acid purification column 5, and the ginkgolic acid purification column 5 is connected with the ginkgolic acid freeze dryer 6.
In particular, CO 2 Gas and crude extract of ginkgo leaf are extracted from supercritical CO 2 The extraction tower 3 enters the tower and is used for supercritical CO 2 Fully mixing in the extraction tower 3, and then using supercritical CO 2 The top of the extraction tower 3 enters the supercritical fluid separation tower 4 through a fluid pressure reducing valve 12, and the inclined plate type barrier 13 separates CO 2 The gas and the crude extract of ginkgolic acid, the liquid part containing the crude extract of ginkgolic acid enters a ginkgolic acid purifying column 5, and the purified ginkgolic acid enters a ginkgolic acid freeze dryer 6 for freeze-drying, pulverizing and granulating.
Wherein: the supercritical fluid separation tower 4 is connected with CO through a pipeline 2 Compressor 10, CO 2 Compressor 10 and CO 2 The storage tanks 1 are connected with each other, CO 2 The gas passes through CO arranged at the top of the supercritical fluid separation tower 4 2 Compressor 10 reinjection into CO 2 A tank 1, thereby realizing CO 2 Recycling and reutilization.
Wherein: the extraction residue continuous purification part comprises an extraction residue fractional distillation tower 7 and a ginkgo leaf active substance storage tank 8, and supercritical CO 2 The extraction tower 3 is connected with a rotary pump 14 through a pipeline, the rotary pump 14 is connected with the extraction residual material fractional distillation tower 7, the extraction residual material fractional distillation tower 7 is connected with the ginkgo leaf active material storage tank 8, and supercritical CO is provided 2 The ginkgolic acid extraction residual materials in the extraction tower 3 enter the extraction residual material fractional rectifying tower 7 through the rotary pump 14 to separate active substances such as flavonoid, terpene lactones and the like, and finally, various active substance crude products after rectification separation and purification enter the ginkgo leaf active substance storage tank 8.
Working principle: the utility model relates to a device for continuously extracting ginkgolic acid by carbon dioxide, CO 2 CO in the tank 1 2 The gas and the crude ginkgo leaf extract in the crude ginkgo leaf extract storage tank 2 are respectively prepared from supercritical CO 2 The bottom and top of the extraction column 3 enter the column, and are subjected to supercritical CO 2 After fully mixing in the extraction tower 3, supercritical CO 2 The fluid is composed of supercritical CO 2 The top of the extraction tower 3 enters the supercritical fluid separation tower 4 through a fluid pressure reducing valve 12;
a bevel board type baffle 13 is arranged in the supercritical fluid separation tower 4 for separating CO 2 Gas and ginkgolic acid coarse extract are separated from each other through gas-liquid separation, and CO 2 The gas passes through CO arranged at the top of the supercritical fluid separation tower 4 2 Compressor 10 reinjection into CO 2 A tank 1, thereby realizing CO 2 Recovering and reutilizing, wherein the liquid part containing the crude extract of ginkgolic acid enters a ginkgolic acid purifying column 5, and the purified ginkgolic acid enters a ginkgolic acid freeze dryer 6 for freeze-drying, pulverizing and granulating;
at the same time, supercritical CO 2 The ginkgolic acid extraction residue in the extraction tower 3 enters the extraction residue fractionation rectifying tower 7 through a rotary pump 14 to separate active substances such as flavonoid, terpene lactones and the like, and finally, the active substances are rectified, separated and purifiedThe crude products of various active substances enter a ginkgo leaf active substance storage tank 8.
What is not described in detail in this specification is prior art known to those skilled in the art.
Although the present utility model has been described with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described, or equivalents may be substituted for elements thereof, and any modifications, equivalents, improvements and changes may be made without departing from the spirit and principles of the present utility model.
Claims (3)
1. The device for continuously extracting ginkgolic acid by using carbon dioxide comprises a supercritical continuous extraction part, a ginkgolic acid purification part and a continuous purification part for extracting residual substances, and is characterized in that: the supercritical continuous extraction part comprises CO 2 Storage tank (1), ginkgo leaf crude extract storage tank (2), supercritical CO 2 An extraction column (3), said CO 2 The outer side of the storage tank (1) is provided with a pressure gauge (9), and the CO 2 The storage tank (1) is connected with supercritical CO through a pressure gauge (9) 2 The extraction tower (3) is connected, a ginkgo leaf crude extract positive displacement pump (11) is arranged on the outer side of the ginkgo leaf crude extract storage tank (2), and the ginkgo leaf crude extract storage tank (2) is connected with supercritical CO through the ginkgo leaf crude extract positive displacement pump (11) 2 The extraction towers (3) are connected;
the ginkgolic acid purification part comprises a supercritical fluid separation tower (4), a ginkgolic acid purification column (5), a ginkgolic acid freeze dryer (6) and a fluid pressure reducing valve (12), wherein the supercritical CO 2 The extraction tower (3) is connected with the supercritical fluid separation tower (4) through a fluid pressure reducing valve (12), an inclined plate type barrier (13) is arranged inside the supercritical fluid separation tower (4), the supercritical fluid separation tower (4) is connected with the ginkgolic acid purification column (5), and the ginkgolic acid purification column (5) is connected with the ginkgolic acid freeze dryer (6).
2. A continuous carbon dioxide extraction process for ginkgolic acids as claimed in claim 1The device is characterized in that: the supercritical fluid separation tower (4) is connected with CO through a pipeline 2 Compressor (10), said CO 2 Compressor (10) and CO 2 The storage tanks (1) are connected.
3. The apparatus for continuously extracting ginkgolic acid with carbon dioxide as claimed in claim 1, wherein: the continuous purification part of the extraction residual substances comprises an extraction residual substance fractional distillation tower (7) and a ginkgo leaf active substance storage tank (8), wherein the supercritical CO 2 The extraction tower (3) is connected with a rotary pump (14) through a pipeline, the rotary pump (14) is connected with the extraction residual material fractional distillation tower (7), and the extraction residual material fractional distillation tower (7) is connected with the ginkgo leaf active material storage tank (8).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320527142.8U CN219376125U (en) | 2023-03-17 | 2023-03-17 | Device for continuously extracting ginkgolic acid by carbon dioxide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320527142.8U CN219376125U (en) | 2023-03-17 | 2023-03-17 | Device for continuously extracting ginkgolic acid by carbon dioxide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219376125U true CN219376125U (en) | 2023-07-21 |
Family
ID=87186519
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320527142.8U Active CN219376125U (en) | 2023-03-17 | 2023-03-17 | Device for continuously extracting ginkgolic acid by carbon dioxide |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219376125U (en) |
-
2023
- 2023-03-17 CN CN202320527142.8U patent/CN219376125U/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103113980B (en) | Efficient extraction and purification method of mandarin peel oil | |
| CN100564373C (en) | From tea tree, extract the complete processing of tea-polyphenol | |
| CN102504957A (en) | Method for preparing essential oils | |
| CN102432582A (en) | Preparation method of proanthocyanidin | |
| CN104673486B (en) | A kind of method for extracting Silybum Marianum Gaertn Seed Oil and silymarin simultaneously in the cake from milk thistle | |
| CN103805341A (en) | Extraction method of orange peel essential oil | |
| CN102001946A (en) | Novel method for simultaneously extracting and separating chlorogenic acid and honeysuckle flower essential oil from honeysuckle flower | |
| CN112940003B (en) | Method for continuously extracting sweet wormwood essential oil and artemisinin | |
| CN101982471A (en) | Technological process for extracting aucubin from fruits of eucommia ulmoides oliver | |
| CN101712643B (en) | Method for extracting high-content lutein by utilizing molecular distillation technology and simulated moving bed technology | |
| CN219376125U (en) | Device for continuously extracting ginkgolic acid by carbon dioxide | |
| CN103012351B (en) | A kind of purifying technique of natural VE | |
| CN104356946A (en) | Method for leaching rosin and heavy oil by crushing rosin residues | |
| CN102038044A (en) | Supercritical CO2 extraction process of onion oil | |
| CN112294725A (en) | Preparation method of rosemary extract | |
| CN219721972U (en) | Carbon dioxide gas adsorption device | |
| CN105669386B (en) | A method of the separation concentration resveratrol from Roots of Peanut extracting solution | |
| CN102432573B (en) | Method for preparing lovastatin | |
| CN101375975A (en) | Novel method for preparing grape seed extract | |
| CN106431895B (en) | Molecular distillation combines extraction for the method for extracting Lactic Acid from Fermentation Broth | |
| CN1063797A (en) | A kind of method of producing flavour-enhanced soluble instant coffee in powder form | |
| CN102653705B (en) | Method for extracting essential oil and natural flavor 2-hendecanone from zanthoxylum bungeanum maxim fruit | |
| CN101638404A (en) | High-purity salvianolic acid B and preparation method and application thereof | |
| CN111647002B (en) | Method for preparing high-purity 1,8-cineole by using alkanediol mixed green solvent | |
| CN1687052A (en) | Method for extracting coumarin substances from rhodiola root of natural plant |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Assignee: JIANGSU FENG-AO BIOLOGICAL TECHNOLOGY CO.,LTD. Assignor: JIANGSU HONGQI BIOTECHNOLOGY Co.,Ltd. Contract record no.: X2024980018021 Denomination of utility model: A device for continuous extraction of ginkgolic acid with carbon dioxide Granted publication date: 20230721 License type: Common License Record date: 20241011 |