CN219375848U

CN219375848U - Chitosan particle cavity channel drug delivery device

Info

Publication number: CN219375848U
Application number: CN202320521242.XU
Authority: CN
Inventors: 潘大庆; 王小营; 阎林胤
Original assignee: Henan Health Guangji Biotechnology Co ltd
Current assignee: Henan Health Guangji Biotechnology Co ltd
Priority date: 2023-03-17
Filing date: 2023-03-17
Publication date: 2023-07-21
Anticipated expiration: 2033-03-17

Abstract

The utility model relates to the technical field of chitosan particle cavity drug delivery, in particular to a chitosan particle cavity drug delivery device, which comprises an inflating bag provided with an air inlet one-way valve, wherein the output end of the inflating bag is connected with a soft inner bag through a connecting one-way valve, one side of the soft inner bag is connected with a drug delivery pipe, a drug delivery nozzle is arranged on the drug delivery pipe, a hard shell is wrapped on the soft inner bag, and one side of the soft inner bag is adhered to the hard shell. The chitosan particle cavity drug feeder provided by the utility model is stable in drug feeding, convenient to operate, convenient to assemble and disassemble, reliable in sealing, capable of avoiding dust from entering, uniform in drug feeding and convenient for adding a medicament, and is used for overcoming the defects in the prior art.

Description

Chitosan particle cavity channel drug delivery device

Technical Field

The utility model relates to the technical field of chitosan particle cavity tract drug delivery, in particular to a chitosan particle cavity tract drug delivery device.

Background

Chitosan is a product of chitosan, which is obtained by partially deacetylating chitin through a chemical method and an enzymatic method, and has various physiological functions of resisting bacteria, resisting inflammation, resisting oxidation, adhering tissues, promoting cell proliferation and differentiation, reducing blood fat, enhancing immunity and the like, so that the chitosan has wide influence in various fields such as biomedical fields, medical absorbable materials, medical fields, drug development and the like. In clinical practice, the dosage forms of natural cavity channels (such as perianal, perineal, ear and the like) and unnatural cavity channels (surgical incision, various through wounds, sinus channels and the like) are found to be solutions, suppositories, ointments, gels, films and the like, but no matter which dosage form is used, the corresponding disadvantages exist, and leakage is easy to occur when the solutions and the suppositories are used for administration; when the ointment and the gel are used for administration, the application is very inconvenient due to the restriction of a cavity, and the wet adhesion of the ointment and the gel is poor, so that the wound healing and the hemostatic effect are affected.

The chitosan can be made into fiber, porous bracket and gel, which can be used for wound healing, hemostasis, tissue engineering and drug delivery, and the chitosan can also be in film or powder form for application of mucous membrane and cavity, however, at present, no particularly suitable administration tool is available, and a direct pouring or coating mode is generally adopted, but the mode has the defects of difficult control of dosage, uneven drug distribution, rough operation mode, poor effect and the like. For this reason, it is often necessary to apply the syringe, i.e., to fill chitosan particles in the syringe, and to push the stem of the syringe to push the chitosan particles out of the syringe, so that the chitosan particles fall on the wound, thereby promoting wound healing and hemostasis. However, when operating personnel push the barrel handle of the needle cylinder, the operating personnel difficultly shake the needle cylinder in the process of pushing the needle cylinder, so that the extrusion of chitosan particle medicament is difficult to stably fall on a wound, the administration effect is influenced, the medicament is wasted, meanwhile, the output of the polysaccharide particle medicament is stumbled and slowed down due to the fact that the pushing speed of the barrel handle is difficult to control, the use of the medicament amount is still difficult to control, the administration pushing speed is too fast, the medicament is easy to stimulate the wound of a patient, and the treatment on the patient is not facilitated. In addition, as the output end of the needle cylinder is of a circular hole-shaped structure, but the wound is of a linear structure, the output end of the needle cylinder needs to be moved along the wound in the drug administration process of operators, the operation of the operators is inconvenient, and as the hole diameter of the output end of the needle cylinder is far larger than the width of the wound, most of medicaments are extruded by the needle cylinder and do not fall on the wound, so that the medicament is wasted.

Therefore, the chitosan particle cavity drug delivery device which is stable in drug delivery, convenient to operate, convenient to assemble and disassemble, reliable in sealing, capable of avoiding dust from entering, uniform in drug delivery and convenient for adding the drug has wide market prospect.

Disclosure of Invention

Aiming at the defects of the prior art, the chitosan particle cavity drug feeder provided by the utility model has the advantages of stable drug feeding, convenience in operation, convenience in loading and unloading, reliability in sealing, capability of avoiding dust from entering, uniformity in drug feeding and convenience in adding a medicament, and is used for overcoming the defects in the prior art.

The utility model adopts the technical scheme that: the utility model provides a chitosan granule passageway ware of dosing, includes the air bag of installing the check valve that admits air, the output of air bag be connected with soft inner bag through connecting the check valve, one side of soft inner bag is connected with the pipe of dosing, installs the shower nozzle of dosing on the pipe of dosing, soft inner bag on wrap up and have the stereoplasm shell, one side of soft inner bag bonds on the stereoplasm shell.

The soft inner bag is communicated and adhered with a luer inner cone connector, the luer inner cone connector is embedded and fixed on the hard shell, the luer inner cone connector is connected with a luer outer cone connector through threads, a connecting pipe is arranged between the luer outer cone connector and the connecting one-way valve, and the luer outer cone connector is connected with the output end of the connecting one-way valve through the connecting pipe.

One side of connecting pipe cover be equipped with the sealing ring, adopt interference connection between sealing ring and the connecting pipe, the sealing ring suit is in luer outer conical joint, one side bonding intercommunication of inflating the gasbag have the inflating pipe, the one side of inflating the tracheal stretch out the pot head dress and being connected the input of check valve, the opposite side of inflating pipe and connecting pipe adopts interference connection with the connection check valve respectively, the connection check valve adopt the round platform structure.

The valve core of the air inlet check valve adopts an I-shaped rod-shaped structure, the valve core of the air inlet check valve is tightly pressed on the valve body of the air inlet check valve through a spring, the air inlet check valve is inlaid and fixed on the inflating bag, the output end of the air inlet check valve is communicated with the inflating bag, and the input end of the air inlet check valve is adhered and sleeved with a screen.

The drug delivery nozzle is sleeved with a drug delivery connector, the drug delivery connector is connected with the drug delivery nozzle by screw threads, and one end of the drug delivery connector is adhered to the drug delivery end of the drug delivery pipe.

The outside of the administration spray head adopts a duckbill structure, a plurality of administration holes are uniformly formed in the outer side face of the administration spray head, the plurality of administration holes are respectively communicated with the inner cavity of the administration spray head, and the diameter of the administration spray head is 2-4mm.

The soft inner bag comprises a soft inner bag, a soft outer shell, a soft sealing plug, a hard outer shell, a drug administration groove, a fixing groove and a sealing plug, wherein the drug administration groove is formed in one side of the soft inner bag, the fixing groove is formed in one side of the hard outer shell and is communicated with an inner cavity of the soft inner bag through the drug administration groove, the sealing plug made of elastic materials is sleeved on the fixing groove, the sealing plug is sleeved on the drug administration groove, and the drug administration groove and the fixing groove are respectively connected with the sealing plug in an interference mode.

The utility model has the beneficial effects that: firstly, the utility model comprises an inflating bag provided with an air inlet one-way valve, the output end of the inflating bag is connected with a soft inner bag through a connecting one-way valve, one side of the soft inner bag is connected with a medicine feeding pipe, a medicine feeding nozzle is arranged on the medicine feeding pipe, a hard shell is wrapped on the soft inner bag, one side of the soft inner bag is adhered to the hard shell, and the utility model separates the storage of chitosan particle medicine from the control of medicine feeding through the inflating bag and the soft inner bag, avoids the instability phenomenon caused by force application in the medicine feeding process, ensures the medicine feeding propulsion rate to be uniform and stable under the action of expansion performance and deformation recovery by virtue of the compression of the soft inner bag, is convenient for controlling medicine quantity, avoids stimulating wounds of patients, facilitates wound healing and hemostasis, protects the soft inner bag through the hard shell, and is convenient for an operator to hold the medicine feeding operation, and ensures the stable operation of the utility model; secondly, the utility model is convenient to assemble and disassemble the inflating bag and the connecting one-way valve from one side of the soft inner bag through the luer inner conical connector and the luer outer conical connector, and the connecting pipe is installed and fixed through the sealing ring, the tightness of the connection of the connecting pipe and the luer outer conical connector is ensured, and the connecting one-way valve is convenient to be installed between the inflating pipe and the connecting pipe through the connecting one-way valve by adopting a round platform structure, so that the connecting one-way valve is convenient to assemble and disassemble, and the utility model is convenient to kill; thirdly, through installing a screen mesh on the air inlet one-way valve, the air bag is prevented from being blown by particles in the air, so that pollution to the medicament and the wound of a patient in the medicament administration process are prevented, the medicament administration nozzle is convenient to assemble and disassemble through the arranged medicament administration joint, the medicament injection nozzle is of a duckbill structure outside, the shape of the medicament injected by the medicament injection nozzle is similar to that of the wound, and the waste of chitosan particle medicament is reduced while the operation difficulty is reduced; in addition, the drug administration groove is formed on one side of the soft inner bag, and the fixing groove is formed on one side of the hard outer shell, so that the drug adding operation is facilitated.

Drawings

Fig. 1 is a schematic structural view of the present utility model.

Fig. 2 is an enlarged schematic view at a in fig. 1.

Fig. 3 is an enlarged schematic view at B in fig. 1.

Fig. 4 is an enlarged schematic view at C in fig. 1.

Fig. 5 is an enlarged schematic view at D in fig. 1.

Fig. 6 is a schematic perspective view of an administration nozzle according to the present utility model.

Detailed Description

As shown in fig. 1, 2, 3, 4, 5 and 6, a chitosan particle cavity drug delivery device comprises an air pumping bag 2 provided with an air inlet one-way valve 1, wherein the output end of the air pumping bag 2 is connected with a soft inner bag 4 through a connecting one-way valve 3, the soft inner bag 4 is used for buffering wind pressure and storing chitosan particle drugs, one side of the soft inner bag 4 is connected with a drug delivery pipe 5, a drug delivery spray head 6 is arranged on the drug delivery pipe 5, the drug delivery spray head 6 is used for dispersing drugs, the soft inner bag 4 is wrapped with a hard shell 7, one side of the soft inner bag 4 is adhered to the hard shell 7, the hard shell 7 is used for protecting the soft inner bag 4, and when the drug delivery device is used, air in the air pumping bag 2 is pressed into the soft inner bag 4 through the connecting one-way valve 3, so that the soft inner bag 4 is expanded by wind pressure, slowed down, and gradually recovers the original state under the action of self deformation recovery of the soft inner bag 4, and simultaneously extrudes the soft inner bag 4, thereby promoting the wound to be healed by the effect of the drug delivery pipe 5, and the drug delivery pipe is more convenient for the drug delivery of the drugs, and the wound can be healed by the drug delivery particles by the drug delivery pipe 5.

The soft inner bag 4 is communicated and adhered with a luer inner cone joint 8, the luer inner cone joint 8 is embedded and fixed on the hard shell 7, the luer inner cone joint 8 is connected with a luer outer cone joint 9 in a threaded manner, a connecting pipe 10 is arranged between the luer outer cone joint 9 and the connecting one-way valve 3, and the luer outer cone joint 9 is connected with the output end of the connecting one-way valve 3 through the connecting pipe 10, so that the air bag 2 and the connecting one-way valve 3 are conveniently assembled and disassembled from one side of the soft inner bag 4, namely, the soft inner bag 4 is conveniently subjected to disinfection treatment; one side of the connecting pipe 10 is sleeved with a sealing ring 11, the sealing ring 11 is in interference connection with the connecting pipe 10, the sealing ring 11 is sleeved in the luer outer conical connector 9, one side of the connecting pipe 10 is fixed in the luer outer conical connector 9, one end of the connecting pipe 10 extends into the luer inner conical connector 8, one side of the inflating bag 2 is adhered and communicated with an inflating pipe 12, the extending end of the inflating pipe 12 is sleeved at the input end of the connecting check valve 3, the inflating pipe 12 and the other side of the connecting pipe 10 are respectively in interference connection with the connecting check valve 3, the connecting check valve 3 adopts a round table structure, and therefore the connecting pipe 10 and the inflating pipe 12 are conveniently and rapidly arranged on the connecting check valve 3 respectively, namely, the connecting check valve 3 is convenient to assemble and disassemble, and the inflating bag 2 is convenient to kill.

The valve core of the air inlet one-way valve 1 adopts an I-shaped rod-shaped structure, the valve core of the air inlet one-way valve 1 is tightly pressed on the valve body of the air inlet one-way valve 1 through a spring, the air inlet one-way valve 1 is inlaid and fixed on the inflating bag 2, the output end of the air inlet one-way valve 1 is communicated with the inflating bag 2, and the input end of the air inlet one-way valve 1 is adhered and sleeved with a screen 13, so that the air bag 2 is prevented from being inflated by particles in the air, namely, the wound of a patient is prevented from being polluted in the drug administration process.

The administration nozzle 6 is sleeved with an administration joint 14, the administration joint 14 is in threaded connection with the administration nozzle 6, the outer diameter of the administration joint 14 is matched with the inner diameter of the administration nozzle 6, one end of the administration joint 14 is adhered to the administration end of the administration tube 5, the administration end of the administration tube 5 is adhered to the soft inner bag 4 and the hard shell 7, and the outer side of the administration joint 14 adopts a round platform structure, so that the administration nozzle 6 is conveniently installed, the administration wind pressure is increased, the administration is more concentrated, the wound is convenient to absorb chitosan particles, and the wound healing and hemostasis are convenient to promote.

The outside of the administration nozzle 6 adopts a duckbill structure, so that the chitosan particle medicament sprayed by the administration nozzle 6 is in a linear shape, namely, the shape of the sprayed chitosan particle medicament is similar to that of a wound, the waste of the chitosan particle medicament is greatly reduced, a plurality of administration holes 15 are uniformly formed in the outer side surface of the administration nozzle 6, the plurality of administration holes 15 are respectively communicated with the inner cavity of the administration nozzle 6, and the diameter of the administration nozzle 6 is 2-4mm, so that the sprayed chitosan particle medicament is prevented from being concentrated in the middle part.

The soft inner bag comprises a soft inner bag 4, a soft outer bag, a soft sealing plug 18, a drug administration groove 16, a fixing groove 17 and a drug administration groove 16, wherein the drug administration groove 16 is formed in one side of the soft inner bag 4, the fixing groove 17 is communicated with the inner cavity of the soft inner bag 4 through the drug administration groove 16, the fixing groove 17 is sleeved with the sealing plug 18 made of elastic materials, the sealing plug 18 is sleeved on the drug administration groove 16, the drug administration groove 16 and the fixing groove 17 are respectively connected with the sealing plug 18 in an interference mode, and the drug administration groove 16 and the fixing groove 17 are used for placing chitosan particle drugs into the soft inner bag 4, so that the drugs can be conveniently added.

The method of the product is as follows: as shown in fig. 1, 2, 3, 4, 5, 6, first, the product to be killed is assembled, a connection pipe 10 and an inflation pipe 12 are respectively installed on both ends of the connection check valve 3, and one end of the connection pipe 10 is passed through the luer outer conical connector 9 and is sleeved in the sealing ring 11, and the luer outer conical connector 9 is installed on the luer inner conical connector 8 such that one end of the connection pipe 10 is inserted into the luer inner conical connector 8; then, the chitosan pellet medicine is introduced into the soft inner bag 4 through the administration groove 16 and the fixing groove 17, and the sealing plug 18 is installed on the administration groove 16 and the fixing groove 17, and the administration nozzle 6 is sleeved on the administration connector 14, thereby facilitating the use operation.

When in use, the drug administration spray head 6 faces the wound of a patient, the air in the air pumping bag 2 is extruded into the soft inner bag 4 through the connecting one-way valve 3 by pressing the air pumping bag 2, so that the drug in the soft inner bag 4 is blown into the drug administration tube 5 and is scattered to the wound through the drug administration spray head 6; then, the air bag 2 is opened by loosening, so that the air bag is gradually restored under the action of self deformation restoration, and air is sucked through the air inlet one-way valve 1; the medicine can be uniformly dropped on the wound by repeatedly pressing the air bag 2, which is convenient for hemostasis and healing of the wound. When the air pumping bag 2 is pressed at too high speed, air in the air pumping bag 2 is rapidly squeezed into the soft inner bag 4, the soft inner bag 4 is inflated by wind pressure, so that the blowing of the medicament is slowed down, and the medicament is gradually reduced and restored to the original state under the action of self deformation and restoration of the soft inner bag 4, so that the redundant air of the soft inner bag 4 is extruded, namely, the chitosan particle medicament is taken into the medicament feeding tube 5, and the medicament is fed to meet the use requirement.

The chitosan particle cavity drug feeder provided by the utility model has the advantages of stable drug feeding, convenience in operation, convenience in loading and unloading, reliability in sealing, capability of avoiding dust from entering, uniformity in drug feeding and convenience in adding a medicament, so that the chitosan particle cavity drug feeder has a wide market prospect.

Claims

1. The utility model provides a chitosan granule chamber way ware of dosing, is including installing air bag (2) of air inlet check valve (1), its characterized in that: the output end of the inflating bag (2) is connected with a soft inner bag (4) through a connecting one-way valve (3), one side of the soft inner bag (4) is connected with a drug administration pipe (5), a drug administration spray head (6) is arranged on the drug administration pipe (5), a hard shell (7) is wrapped on the soft inner bag (4), and one side of the soft inner bag (4) is bonded on the hard shell (7).

2. The chitosan particle cavity applicator of claim 1, wherein: the soft inner bag (4) is communicated and adhered with a luer inner conical connector (8), the luer inner conical connector (8) is embedded and fixed on the hard outer shell (7), the luer inner conical connector (8) is connected with a luer outer conical connector (9) in a threaded mode, a connecting pipe (10) is arranged between the luer outer conical connector (9) and the connecting one-way valve (3), and the luer outer conical connector (9) is connected with the output end of the connecting one-way valve (3) through the connecting pipe (10).

3. The chitosan particle cavity applicator of claim 2, wherein: one side of connecting pipe (10) suit be equipped with sealing ring (11), adopt interference connection between sealing ring (11) and connecting pipe (10), sealing ring (11) suit is in luer outer conical joint (9), one side of inflating bag (2) bond the intercommunication and have inflating pipe (12), the end suit that stretches out of inflating pipe (12) is at the input of connecting check valve (3), the opposite side of inflating pipe (12) and connecting pipe (10) adopts interference connection with connecting check valve (3) respectively, connecting check valve (3) adopt round platform structure.

4. The chitosan particle cavity applicator of claim 1, wherein: the valve core of the air inlet check valve (1) adopts an I-shaped rod-shaped structure, the valve core of the air inlet check valve (1) is pressed on the valve body of the air inlet check valve (1) through a spring, the air inlet check valve (1) is inlaid and fixed on the inflating bag (2), the output end of the air inlet check valve (1) is communicated with the inflating bag (2), and the input end of the air inlet check valve (1) is adhered and sleeved with a screen (13).

5. The chitosan particle cavity applicator of claim 1, wherein: the drug delivery nozzle (6) is sleeved with a drug delivery joint (14), the drug delivery joint (14) is in threaded connection with the drug delivery nozzle (6), and one end of the drug delivery joint (14) is adhered to the drug outlet end of the drug delivery pipe (5).

6. The chitosan particle cavity applicator of claim 1, wherein: the outside of dosing shower nozzle (6) adopt duckbill structure, evenly offered a plurality of hole (15) of dosing on the lateral surface of dosing shower nozzle (6), a plurality of hole (15) of dosing are linked together with the inner chamber of dosing shower nozzle (6) respectively, and the diameter of dosing shower nozzle (6) is 2-4mm.

7. The chitosan particle cavity applicator of claim 1, wherein: a drug delivery groove (16) is formed in one side of the soft inner bag (4), a fixing groove (17) is formed in one side of the hard outer shell (7), the fixing groove (17) is communicated with an inner cavity of the soft inner bag (4) through the drug delivery groove (16), a sealing plug (18) made of elastic materials is sleeved on the fixing groove (17), the sealing plug (18) is sleeved on the drug delivery groove (16), and the drug delivery groove (16) and the fixing groove (17) are connected with the sealing plug (18) in an interference mode.