CN219375746U - Nasal cavity drug delivery device suitable for powdery drug - Google Patents

Nasal cavity drug delivery device suitable for powdery drug Download PDF

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Publication number
CN219375746U
CN219375746U CN202220407315.8U CN202220407315U CN219375746U CN 219375746 U CN219375746 U CN 219375746U CN 202220407315 U CN202220407315 U CN 202220407315U CN 219375746 U CN219375746 U CN 219375746U
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medicine
air
drug
delivery device
nasal cavity
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CN202220407315.8U
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Chinese (zh)
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李娜
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Zhongda Hospital of Southeast University
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Zhongda Hospital of Southeast University
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The utility model discloses a nasal cavity drug delivery device suitable for powdery drugs, which comprises a shell, wherein a front side wall and a rear side wall in the shell are respectively provided with a limiting block, the middle parts of opposite surfaces of the two limiting blocks are respectively provided with an arc-shaped groove, a drug outlet roller is arranged between the two arc-shaped grooves, two ends of the drug outlet roller are respectively and rotatably connected with the side walls of the left end and the right end of the shell, the outer side surface of the side wall of the right end of the shell is provided with a knob for driving the drug outlet roller to rotate, the outer circumferential surface of the drug outlet roller is uniformly and circumferentially provided with a plurality of drug storage grooves, a drug inlet channel is formed between the opposite surfaces of the two limiting blocks positioned above the drug outlet roller, a drug outlet channel is formed between the opposite surfaces of the two limiting blocks positioned below the drug outlet roller, and a drug delivery airflow channel matched and communicated with the drug outlet channel is arranged at the bottom of the shell; the powder medicine is directly packaged in the shell of the nasal cavity medicine delivery device, a capsule is not required to be placed or a bubble cap strip with a medicine bin is not required to be replaced when the nasal cavity medicine delivery device is used, the use process is simple and convenient, and continuous medicine delivery can be realized.

Description

Nasal cavity drug delivery device suitable for powdery drug
Technical Field
The utility model relates to a nasal cavity drug delivery device suitable for powdery drugs, and belongs to the technical field of medical appliances.
Background
The nasal administration refers to a mode of administration in which the drug is directly delivered into the nasal cavity through the nostril, drug particles are firstly deposited on a specific area on the inner surface of the nasal cavity, then penetrate through a mucus layer and a mucous membrane epithelial cell layer, and further reach the action part of the drug, so as to treat local diseases of the nasal cavity and brain and systemic diseases; the traditional nasal administration is generally used for treating nasal cavity local diseases (rhinitis, nasal polyp, nasosinusitis and the like) and nasal cavity operation postoperation, and the medicine is directly delivered to a nasal cavity focus, so that the medicine can exert better medicine effect, and toxic and side effects caused by the medicine reaching the whole body tissues through blood circulation can be reduced; since nasal administration has the advantages of avoiding the first pass effect of the liver, improving the effectiveness of the drug entering the brain, having high bioavailability, and the like, the drug has been paid more attention to by more researchers; nasal delivery devices have a critical role in drug bioavailability, particularly for delivery to the olfactory region for the treatment of brain diseases, and in recent years, new nasal delivery has been increasingly used to treat brain diseases and systemic diseases; because the surface layer of the nasal mucosa is provided with a plurality of tiny villi, the effective area of drug absorption can be increased, and the lower layer of the epithelial cells of the nasal mucosa is provided with abundant capillaries and capillary lymphatic vessels, so that the blood flow is abundant, and drug molecules can be rapidly absorbed by the nasal mucosa to enter the capillaries so as to enter the blood circulation for treating upper respiratory diseases and systemic diseases; the nasal mucosa has higher penetrability and relatively less enzyme, and has lower decomposition effect on protein medicines than gastrointestinal mucosa, thereby being beneficial to the absorption of medicines and the direct entering of blood circulation in human body; at present, in the traditional nasal cavity administration device, if the medicine is in a powder form or a granular form, the medicine is packaged in a capsule or a bubble cap strip with a medicine bin, when the medicine is administered to the nasal cavity, the capsule or the bubble cap strip with the medicine bin is required to be pierced by a sharp device, and then the leaked powder or granular medicine is blown into the nasal cavity by air flow, so that nasal cavity administration is realized; after the nasal cavity administration is finished, the capsule is taken out and discarded, or a bubble cap strip with a medicine bin is replaced periodically; the whole process is troublesome, the used capsules for packaging medicines are required to be processed after each administration or the used blister strips with medicine bins are required to be processed regularly, and the placement of the capsules or the replacement of the blister strips with medicine bins are also troublesome.
Disclosure of Invention
The utility model aims at solving the problems in the prior art and providing a nasal cavity administration device suitable for powdery medicines, which enables the powdery medicines to be directly packaged in a shell of the nasal cavity administration device, redesigns a medicine outlet structure and an administration air flow passage structure, does not need to place capsules or replace a bubble cap strip with a medicine bin when in use, and avoids the need to process the used capsules for packaging medicines or the bubble cap strip with the medicine bin after being treated periodically after each administration; the use process is simple and convenient, and continuous administration can be realized.
In order to achieve the above object, the present utility model adopts the following technical scheme:
the utility model provides a nasal cavity device of dosing suitable for powdered medicine, includes the casing, the inside preceding lateral wall of casing and back lateral wall are provided with the stopper respectively, and two stopper symmetrical arrangement are formed with the arc recess respectively in the middle part of two stopper opposite faces, are provided with out the medicine passageway between two arc recesses, go out the both ends of medicine passageway respectively with the left and right sides lateral wall rotation of casing be connected, be provided with the knob that is used for driving out the medicine passageway rotatory at the lateral surface of casing right-hand member lateral wall, go out the outer periphery of medicine passageway and the wall in two arc recess in close sliding contact, the outer periphery of going out the medicine passageway evenly circumference of medicine passageway is provided with a plurality of medicine storage tank, the medicine storage tank constitutes into the medicine passageway along going out the axial extension of medicine passageway between two stopper opposite faces of medicine passageway top, is located and goes out between two stopper opposite faces of medicine passageway below, is provided with the medicine passageway of being linked together with out the medicine passageway in the bottom of casing, and one of which one end of medicine passageway is provided with the intake pipe that is used for inserting into the nasal cavity.
As a further preferred aspect of the present utility model, the drug delivery air flow channel extends in the axial direction of the drug delivery roller, and the cross-sectional shape of the drug delivery air flow channel is semicircular.
As a further preferred aspect of the present utility model, the cross-sectional area of the administration air flow path gradually increases from the air inlet pipe toward the nasal cavity pipe; the air in the feeding air flow channel blows the powder medicine to the nasal cavity tube.
As a further preferable aspect of the present utility model, the cross-sectional shape of the medicine feed passage is an inverted trapezoid with a wide upper part and a narrow lower part; the powder medicine inside the shell body can enter the medicine storage groove through the medicine inlet channel.
As a further preferable aspect of the present utility model, the cross-sectional shape of the medicine outlet channel is a trapezoid with a narrow upper part and a wide lower part; the powder medicine in the medicine storage groove can fall into the medicine feeding airflow channel through the medicine outlet channel.
As a further preferable mode of the utility model, the top of the shell is provided with a dosing port, and a sealing cover is detachably connected to the dosing port; when the residual amount of the powdery medicine in the shell is not large, new powdery medicine can be added into the shell through the medicine adding port.
As a further preferable mode of the utility model, the outer circumferential surface of the knob is sleeved with a rubber sleeve with an anti-skid grain structure; the user can conveniently rotate the knob by the finger; a mark for indicating the position of the medicine storage groove is arranged on the end face of the knob; the position of the medicine storage groove after the knob rotates can be known through the mark.
As a further preferred aspect of the present utility model, the housing is a transparent material; the residual quantity of the powdery medicine in the shell can be intuitively seen.
As a further preferred aspect of the present utility model, the air supply device is an air blowing assembly, the air blowing assembly includes an air blowing nozzle, an air blowing pipe and a joint pipe which are sequentially connected, and the inner circumferential surface of the joint pipe is in threaded connection with the outer circumferential surface of the air inlet pipe; the user can blow air into the drug administration airflow passage by using his own mouth.
As a further preferred aspect of the present utility model, the air supply device is an air bag assembly, the air bag assembly includes an air inlet one-way valve, an air bag and an air outlet one-way valve which are sequentially connected, and the inner circumferential surface of the outlet end of the air outlet one-way valve is in threaded connection with the outer circumferential surface of the air inlet pipe; the air inlet one-way valve can only be used for air inlet, the air outlet one-way valve can only be used for air outlet, and when the air bag is compressed, the air in the air bag can only flow into the drug delivery air flow channel through the air outlet one-way valve; when the air bag is released, the air bag can only suck external air into the air bag through the air inlet one-way valve; the air bag is convenient for a user to hold by the hand, so that the air in the air bag enters the drug administration airflow channel.
The utility model has the advantages that:
the powder medicine is directly packaged in the shell of the nasal cavity medicine feeding device, the medicine discharging roller is driven to rotate by the knob, so that the medicine storage groove on the medicine discharging roller is correspondingly communicated with the medicine feeding channel, and at the moment, the powder medicine in the shell enters the medicine storage groove; then the medicine discharging roller is rotated again, so that the medicine storage groove filled with the powdery medicine is correspondingly communicated with the medicine discharging channel, and at the moment, the powdery medicine in the medicine storage groove falls into the medicine feeding airflow channel through the medicine discharging channel; then the nasal cavity tube is inserted into the nasal cavity, the air supply device is used for supplying air to the air supply channel, and the air flowing into the air supply channel drives the powdery medicine to quickly flow into the nasal cavity tube and enter the nasal cavity through the nasal cavity tube; completing a nasal cavity administration process; the powder medicine is directly packaged in the shell of the nasal cavity medicine delivery device, and the medicine outlet structure and the medicine delivery airflow channel structure are redesigned, so that a capsule is not required to be placed or a bubble cap strip with a medicine bin is not required to be replaced when the nasal cavity medicine delivery device is used, and the situation that the used capsule for packaging the medicine or the used bubble cap strip with the medicine bin is required to be treated after each medicine delivery is finished is avoided; the use process is simple and convenient, and continuous administration can be realized.
Drawings
FIG. 1 is a schematic cross-sectional view of the present utility model;
FIG. 2 is a schematic diagram of a cross-sectional structure of the present utility model;
FIG. 3 is a schematic view of the structure of the blowing assembly of the present utility model;
FIG. 4 is a schematic view of the structure of the airbag module of the present utility model;
FIG. 5 is a schematic cross-sectional view of the nasal cavity tube of the present utility model in a tilted orientation away from the housing;
meaning of reference numerals in the drawings:
1-shell, 2-limited block, 3-medicine discharging roller, 4-knob, 5-medicine storage groove, 6-medicine discharging channel, 7-medicine feeding air flow channel, 8-air inlet pipe, 9-nasal cavity pipe, 10-powdery medicine, 11-medicine feeding port, 12-air blowing nozzle, 13-air blowing pipe, 14-joint pipe, 15-air inlet check valve, 16-air bag and 17-air outlet check valve.
Detailed Description
The utility model is described in detail below with reference to the drawings and the specific embodiments.
Example 1
As shown in fig. 1-3, this embodiment is a nasal cavity drug delivery device suitable for powdery drugs, which comprises a housing 1, the inside front side wall and the back side wall of housing 1 are provided with stopper 2 respectively, two stopper 2 symmetrical arrangement, the middle part of two stopper 2 opposite faces is formed with arc recess respectively, be provided with out drug roller 3 between two arc recesses, the both ends of out drug roller 3 are connected with the left and right sides lateral wall rotation of housing 1 respectively, the lateral surface of housing 1 right-hand member lateral wall is provided with the knob 4 that is used for driving out drug roller 3 rotatory, the outer periphery of out drug roller 3 and the wall in two arc recess closely sliding contact, the outer periphery of out drug roller 3 evenly circumference is provided with four medicine storage groove 5, medicine storage groove 5 extends along the axial of out drug roller 3, constitute the feed channel between two stopper 2 opposite faces of out drug roller 3 top, constitute out drug channel 6 between two stopper 2 opposite faces of being located out drug roller 3 below, be provided with the bottom of housing 1 with out drug channel 6 cooperation intercommunication's drug delivery air current 7, wherein be provided with the air inlet pipe 9 and be provided with the one end of vertical nasal cavity 9 of pipe, wherein, the one end 9 is used for inserting into the vertical nasal cavity device, and is provided with the air inlet pipe 9.
In practical application, the outer circumference of the medicine discharging roller 3 may be uniformly circumferentially provided with a plurality of medicine storing grooves 5, for example: only one medicine storage groove 5 is arranged, so that medicine is discharged once every time the medicine discharging roller 3 rotates one circle; if two medicine storage tanks 5 are arranged, medicine is discharged once every half revolution of the medicine discharging roller 3.
In the present embodiment, the drug delivery air flow channel 7 extends in the axial direction of the drug delivery roller 3, and the cross-sectional shape of the drug delivery air flow channel 7 is a semicircle; the cross-sectional area of the administration air flow passage 7 gradually increases from the air inlet pipe 8 to the nasal cavity pipe 9; the gas which is easy to enter the administration air flow path 7 blows the powdery medicine 10 to the nasal cavity tube 9.
In the embodiment, the cross section of the medicine feeding channel is in an inverted trapezoid shape with a wide upper part and a narrow lower part; the powder medicine 10 in the shell 1 can enter the medicine storage tank 5 through the medicine inlet channel conveniently; the cross section of the medicine outlet channel 6 is trapezoid with narrow upper part and wide lower part; the powder medicine 10 in the medicine storage groove 5 is convenient to fall into the medicine feeding airflow channel 7 through the medicine outlet channel 6.
In the embodiment, the top of the shell 1 is provided with a medicine adding port 11, and a sealing cover is detachably connected at the medicine adding port 11; when the remaining amount of the powdery medicine 10 in the interior of the housing 1 is not large, a new powdery medicine 10 can be added to the interior of the housing 1 through the medicine adding port 11.
In the embodiment, the outer circumferential surface of the knob 4 is sleeved with a rubber sleeve with an anti-skid grain structure; the user can conveniently rotate the knob 4 by the finger; a mark for indicating the position of the medicine storage groove 5 is arranged on the end face of the knob 4; the position of the medicine storage groove 5 after the knob 4 rotates can be known through the mark.
In this embodiment, the housing 1 is made of a transparent material; the remaining amount of the powdered medicine 10 inside the housing 1 can be intuitively seen.
In the embodiment, the air supply device is an air blowing assembly, and the air blowing assembly comprises an air blowing nozzle 12, an air blowing pipe 13 and a joint pipe 14 which are sequentially connected, wherein the inner circumferential surface of the joint pipe 14 is in threaded connection with the outer circumferential surface of the air inlet pipe 8; the user can blow air into the administration air flow path 7 by using his own mouth.
Example two
As shown in fig. 1, 2 and 4, this embodiment is a nasal administration device suitable for powder-like medicines, and is similar to the first embodiment in structure, but differs from the first embodiment only in that: the air supply device in the embodiment is an air bag assembly, and the air bag assembly comprises an air inlet one-way valve 15, an air bag 16 and an air outlet one-way valve 17 which are sequentially connected, wherein the inner circumferential surface of the outlet end of the air outlet one-way valve 17 is in threaded connection with the outer circumferential surface of the air inlet pipe 8; the air inlet one-way valve 15 can only be used for air inlet, the air outlet one-way valve 17 can only be used for air outlet, and when the air bag 16 is compressed, the air in the air bag 16 can only flow into the drug administration air flow channel 7 through the air outlet one-way valve 17; when the air bag 16 is released, the air bag 16 can only suck external air into the air bag 16 through the air inlet check valve 15; the user can conveniently hold the air bag 16 by his or her own hand, so that the air in the air bag 16 enters the drug administration air flow passage 7.
Example III
As shown in fig. 1, 3 and 5, this embodiment is a nasal administration device suitable for powder-like medicines, and is similar to the first embodiment in structure, but differs from the first embodiment only in that: the nasal cavity tube 9 in this embodiment is inclined in a direction away from the housing 1, so that the air flow in the administration air flow channel 7 can drive the powdered medicine 10 to quickly flow into the nasal cavity tube 9 and enter the nasal cavity through the nasal cavity tube 9.
The use process and principle of the three embodiments are as follows:
the powdery medicine 10 is directly packaged in the shell 1 of the nasal cavity medicine feeding device, the medicine discharging roller 3 is driven to rotate by the knob 4, so that the medicine storage groove 5 on the medicine discharging roller 3 is correspondingly communicated with the medicine feeding channel, and at the moment, the powdery medicine 10 in the shell 1 enters the medicine storage groove 5; then the medicine discharging roller 3 is rotated again, so that the medicine storing groove 5 filled with the powdery medicine 10 is correspondingly communicated with the medicine discharging channel 6, and at the moment, the powdery medicine 10 in the medicine storing groove 5 falls into the medicine feeding air flow channel 7 through the medicine discharging channel 6; then the nasal cavity tube 9 is inserted into the nasal cavity, the air supply device is used for supplying air to the air supply channel 7, and the air flowing into the air supply channel 7 drives the powdery medicine 10 to quickly flow into the nasal cavity tube 9 and enter the nasal cavity through the nasal cavity tube 9; completing a nasal cavity administration process; the powder medicine 10 is directly packaged in the shell 1 of the nasal cavity medicine delivery device, and the medicine outlet structure and the medicine delivery airflow channel 7 structure are redesigned, so that a capsule is not required to be placed or a bubble cap strip with a medicine bin is not required to be replaced when the nasal cavity medicine delivery device is used, and the situation that the used capsule for packaging the medicine or the bubble cap strip with the medicine bin is required to be treated after the medicine delivery is finished every time is avoided; the use process is simple and convenient, and continuous administration can be realized.
In the description of the present utility model, it should be understood that the terms "center", "longitudinal", "lateral", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present utility model and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present utility model.
In the description of the present utility model, it should be noted that, unless explicitly stated and limited otherwise, the terms "mounted," "connected," and "configured" are to be construed broadly, and may be, for example, fixedly connected, configured, detachably connected, configured, or integrally connected, configured; can be mechanically or electrically connected; can be directly connected, can also be indirectly connected through an intermediate medium, and can also be the communication between the two elements; the specific meaning of the above terms in the present utility model can be understood by those of ordinary skill in the art according to the specific circumstances.
In the description of the present specification, descriptions of terms "one embodiment," "some embodiments," "examples," "specific examples," "some examples," or "practical applications," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present utility model; in this specification, schematic representations of the above terms do not necessarily refer to the same embodiments or examples; furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The foregoing has shown and described the basic principles, principal features and advantages of the utility model; it will be appreciated by persons skilled in the art that the above embodiments are not intended to limit the utility model in any way, and that all technical solutions obtained by means of equivalent substitutions or equivalent transformations fall within the scope of the utility model.

Claims (10)

1. A nasal delivery device for a powdered medicament, comprising: including the casing, the inside preceding lateral wall of casing and back lateral wall are provided with the stopper respectively, and two stopper symmetrical arrangement, the middle part of two stopper opposite faces is formed with the arc recess respectively, is provided with out the medicine passageway between two arc recesses, go out the both ends of medicine roller respectively with the left and right sides end lateral wall rotation of casing be connected, be provided with the knob that is used for driving out the medicine roller rotation at the lateral surface of casing right-hand member lateral wall, go out the outer periphery of medicine roller and the wall in two arc recesses closely sliding contact, the outer periphery of going out the medicine roller evenly circumference is provided with a plurality of medicine storage groove, the medicine storage groove is along the axial extension of going out the medicine roller, is located and constitutes out the medicine passageway between two stopper opposite faces of medicine roller top, is provided with the medicine air current passageway that feeds out the cooperation of medicine passageway intercommunication in the bottom of casing, and one of which the end of medicine current passageway is provided with the intake pipe with the air feeder intercommunication, and the other one end of medicine current passageway is provided with the nasal cavity pipe that is used for inserting.
2. A nasal delivery device for powdered medicaments according to claim 1, wherein the delivery gas flow path extends in the axial direction of the dispensing roller and the delivery gas flow path is semi-circular in cross-sectional shape.
3. A nasal delivery device for powdered medicaments according to claim 1 or claim 2, wherein the cross-sectional area of the delivery air flow path increases progressively from the inlet conduit towards the nasal tube.
4. A nasal delivery device for powdered medicaments according to claim 1, wherein the cross-sectional shape of the feed passage is an inverted trapezoid with a wider upper portion and a narrower lower portion.
5. A nasal delivery device for powdered medicaments according to claim 1, wherein the cross-sectional shape of the delivery channel is trapezoidal with a narrow upper portion and a wide lower portion.
6. A nasal delivery device for powdered medicaments according to claim 1, wherein the top of the housing is provided with a dosing port and a sealing cap is detachably connected to the dosing port.
7. The nasal cavity drug delivery device suitable for powdery drugs according to claim 1, wherein the outer circumference of the knob is sleeved with a rubber sleeve with an anti-skid texture structure; a mark for indicating the position of the medicine storage groove is arranged on the end face of the knob.
8. A nasal delivery device for powdered medicaments according to claim 1, wherein the housing is a transparent material.
9. The nasal administration device for powdered medicaments according to claim 1, wherein the air supply device is an air blowing assembly comprising an air blowing nozzle, an air blowing pipe and a joint pipe which are sequentially connected, and the inner circumferential surface of the joint pipe is in threaded connection with the outer circumferential surface of the air inlet pipe.
10. The nasal administration device for powdered medicaments according to claim 1, wherein the air supply device is an air bag assembly, the air bag assembly comprises an air inlet one-way valve, an air bag and an air outlet one-way valve which are sequentially connected, and the inner circumferential surface of the outlet end of the air outlet one-way valve is in threaded connection with the outer circumferential surface of the air inlet pipe.
CN202220407315.8U 2022-02-28 2022-02-28 Nasal cavity drug delivery device suitable for powdery drug Active CN219375746U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202220407315.8U CN219375746U (en) 2022-02-28 2022-02-28 Nasal cavity drug delivery device suitable for powdery drug

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202220407315.8U CN219375746U (en) 2022-02-28 2022-02-28 Nasal cavity drug delivery device suitable for powdery drug

Publications (1)

Publication Number Publication Date
CN219375746U true CN219375746U (en) 2023-07-21

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202220407315.8U Active CN219375746U (en) 2022-02-28 2022-02-28 Nasal cavity drug delivery device suitable for powdery drug

Country Status (1)

Country Link
CN (1) CN219375746U (en)

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