CN219308768U - Pipetting Tip head and pipetting device - Google Patents

Abstract

The pipetting Tip head is of a rotationally symmetrical structure along an axis and surrounds liquid storage cavities penetrating through two ends of the axis, and the liquid storage cavities are used for storing liquid; the pipetting Tip head comprises a connecting section, a first liquid storage section, a transition section, a second liquid storage section and a liquid suction section which are sequentially connected along the axial direction, the first liquid storage section, the transition section, the second liquid storage section and the liquid suction section are all in a necking shape along the direction of the liquid suction section, the minimum inner diameter of the first liquid storage section is larger than the maximum inner diameter of the second liquid storage section, the connecting section is used for being detachably connected with an adapter, the liquid suction section is used for sucking liquid or spitting liquid, and the pipetting Tip head has the structure that a large-volume liquid storage cavity can be designed and formed, compared with the current Tip head, the capacity of single pipetting can be obviously increased, the required capacity can be achieved through one-time pipetting operation, and pipetting efficiency can be improved.

Description

Pipetting Tip head and pipetting device

Technical Field

The utility model relates to the technical field of pipetting, in particular to a pipetting Tip head and a pipetting device.

Background

The Tip head (also called as a suction head or a gun head) is used as a consumable matched with a pipetting device and is used for being matched with the pipetting device to realize pipetting and spitting operations on a liquid sample so as to finish pipetting of the liquid sample, and is widely applied to the fields of medical research, biochemical research and the like.

The structural arrangement of the current Tip head is unreasonable, so that the single pipetting capacity is smaller, and when the pipetting operation with larger capacity is needed, the required capacity can be achieved only by pipetting for multiple times, so that the pipetting efficiency is low.

Disclosure of Invention

The utility model aims to provide a pipetting Tip head and a pipetting device, which solve the problems of small single pipetting capacity and low pipetting efficiency caused by unreasonable structure of the current Tip head.

In order to achieve the purpose of the utility model, the utility model provides the following technical scheme:

in a first aspect, the utility model provides a pipetting Tip head, wherein the pipetting Tip head is in a rotationally symmetrical structure along an axis and surrounds liquid storage cavities penetrating through two ends of the axis, and the liquid storage cavities are used for storing liquid; the pipetting Tip head comprises a connecting section, a first liquid storage section, a transition section, a second liquid storage section and a liquid suction section which are sequentially connected along the axial direction, the first liquid storage section, the transition section, the second liquid storage section and the liquid suction section are all in a necking shape, the minimum inner diameter of the first liquid storage section is larger than the maximum inner diameter of the second liquid storage section, the connecting section is used for being detachably connected with an adapter, and the liquid suction section is used for sucking or spitting liquid.

In one embodiment, the inner wall of the first liquid storage section has a first included angle with the axis, the outer wall of the first liquid storage section has a second included angle with the axis, and the first included angle is smaller than or equal to the second included angle.

In one embodiment, one end of the transition section is tangentially connected to the first reservoir section and the other end of the transition section is tangentially connected to the second reservoir section.

In one embodiment, the transition section comprises a first arc portion and a second arc portion, one end of the first arc portion is tangentially connected with the first liquid storage section, one end of the second arc portion is tangentially connected with the other end of the first arc portion, and the other end of the second arc portion is tangentially connected with the second liquid storage section.

In one embodiment, the first arcuate portion projects away from the axis and the second arcuate portion projects toward the axis.

In one embodiment, the inner wall of the second liquid storage section has a third included angle with the axis, the outer wall of the second liquid storage section has a fourth included angle with the axis, and the third included angle is smaller than or equal to the fourth included angle.

In one embodiment, the inner wall of the liquid absorbing section and the axis have a fifth included angle, and the outer wall of the liquid absorbing section and the axis have a sixth included angle, and the fifth included angle is smaller than or equal to the sixth included angle.

In one embodiment, the included angle between the inner wall of the first liquid storage section and the axis is a first included angle, the included angle between the inner wall of the second liquid storage section and the axis is a third included angle, and the third included angle is greater than or equal to the first included angle.

In one embodiment, the inner wall of the second liquid storage section has a third included angle with the axis, and the inner wall of the liquid absorbing section has a fifth included angle with the axis, and the fifth included angle is larger than the third included angle.

In one embodiment, the included angle between the inner wall of the connecting section and the axis is equal to the included angle between the inner wall of the first liquid storage section and the axis; and/or the included angle between the outer wall of the connecting section and the axis is equal to the included angle between the outer wall of the first liquid storage section and the axis; and/or, the inner diameter of the connecting section is larger than the maximum inner diameter of the first liquid storage section.

In one embodiment, the volume of the liquid storage cavity is 4ml-6ml; and/or the inner diameter of the end part of the connecting section far away from the first liquid storage section is 10mm-14mm; and/or the inner diameter of the end part of the liquid absorbing section far away from the second liquid storage section is 0.8mm-1.2mm.

In one embodiment, at least two of the connecting section, the first fluid storage section, the transition section, the second fluid storage section, and the fluid intake section are of unitary construction.

In one embodiment, a chamfer is formed between the end surface of the connecting section far away from the first liquid storage section and the inner wall; the outer wall of the connecting section is provided with a reinforcing part, and the reinforcing part is used for reinforcing the structural strength of the connecting section so that the connecting section is stably connected with the adapter.

In one embodiment, the reinforcement portion includes an annular protrusion extending in a circumferential direction of the connection section and connected end to end, the annular protrusion being provided on an outer wall of an end of the connection section remote from the first liquid storage section and protruding with respect to the outer wall of the connection section; the reinforcing part further comprises a plurality of reinforcing ribs extending along the axial direction of the connecting section, the reinforcing ribs are distributed along the circumferential direction of the connecting section and are arranged on the outer wall of the connecting section at equal interval, and one ends of the reinforcing ribs are connected with the annular protrusions.

In a second aspect, the present utility model further provides a pipetting device comprising a pipetting mechanism, an adapter and a pipetting Tip according to any of the various embodiments of the first aspect, one end of the adapter being detachably connected to the pipetting mechanism and the other end of the adapter being detachably connected to a connecting section of the pipetting Tip.

In one embodiment, the pipetting device further comprises a carrying mechanism, wherein the carrying mechanism is connected with the pipetting mechanism and is used for driving the pipetting mechanism to move.

According to the pipetting Tip head provided by the utility model, the connecting section, the first liquid storage section, the transition section, the second liquid storage section and the liquid absorption section are arranged, and the first liquid storage section, the transition section, the second liquid storage section and the liquid absorption section are all in a necking shape along the direction from the connecting section to the liquid absorption section, the minimum inner diameter of the first liquid storage section is larger than the maximum inner diameter of the second liquid storage section, so that a liquid storage cavity with a large volume (for example, the volume of the liquid storage cavity at the first liquid storage section is larger) can be designed, compared with the conventional Tip head, the single pipetting capacity can be obviously increased, and the required capacity can be achieved through one pipetting operation, thereby the pipetting efficiency can be improved.

Drawings

In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings which are used in the description of the embodiments or the prior art will be briefly described, it being obvious that the drawings in the description below are only some embodiments of the utility model, and that other drawings can be obtained from them without inventive effort for a person skilled in the art.

FIG. 1 is a perspective view of a pipetting Tip head of an embodiment;

FIG. 2 is a side view of a pipetting Tip head of an embodiment;

FIG. 3 is a cross-sectional view taken along the direction A-A in FIG. 2;

FIG. 4 is a schematic illustration of a pipetting Tip head in connection with an adapter in one embodiment;

fig. 5 is a sectional view taken along the direction B-B in fig. 4.

Reference numerals illustrate:

100-pipetting Tip head, 101-liquid storage cavity, 102-connector, 103-liquid suction port, 10-connecting section, 11-inner wall of connecting section, 12-outer wall of connecting section, 13-chamfer, 14-annular bulge, 15-reinforcing rib, 16-annular groove, 20-first liquid storage section, 21-inner wall of first liquid storage section, 22-outer wall of first liquid storage section, 30-transition section, 31-first circular arc portion, 32-second circular arc portion, 40-second liquid storage section, 41-inner wall of second liquid storage section, 42-outer wall of second liquid storage section, 50-liquid suction section, 51-inner wall of liquid suction section, 52-outer wall of liquid suction section, 60-axis, 200-adapter.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all embodiments of the utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the present utility model without making any inventive effort, are intended to fall within the scope of the present utility model.

It will be understood that when an element is referred to as being "fixed to" another element, it can be directly on the other element or intervening elements may also be present. When a component is considered to be "connected" to another component, it can be directly connected to the other component or intervening components may also be present.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this utility model belongs. The terminology used in the description of the utility model herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the utility model. The term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.

Some embodiments of the present utility model are described in detail below with reference to the accompanying drawings. The following embodiments and features of the embodiments may be combined with each other without conflict.

Referring to fig. 1 to 3, an embodiment of the present utility model provides a pipetting Tip head 100, where the pipetting Tip head 100 has a rotationally symmetrical structure along an axis 60. The shape of the pipetting Tip head 100 in any cross section perpendicular to the axis 60 is circular, i.e. the pipetting Tip head 100 comprises an inner wall and an outer wall, both circular and concentric in shape in a cross section perpendicular to the axis 60. The axis 60 is the centerline of the pipetting Tip 100 and is virtual rather than physical. The pipetting Tip head 100 encloses a liquid storage cavity 101 penetrating through two axial ends, and the liquid storage cavity 101 is used for liquid storage. Referring to fig. 3 to 5, one of two ends is used for connecting with the adapter 200, and the end is provided with a connection port 102; the other end of the penetration is used for sucking and discharging liquid, and the end is provided with a liquid sucking port 103. The connection port 102 and the liquid suction port 103 are both communicated with the liquid storage cavity 101, and the connection port 102 and the liquid suction port 103 are both rotationally symmetrical along the axis 60.

Specifically, the pipetting Tip 100 includes a connection section 10, a first reservoir section 20, a transition section 30, a second reservoir section 40, and a pipetting section 50, which are sequentially connected in the axial direction (i.e., the extending direction of the axis 60, the same applies hereinafter). The connecting section 10 is provided with a connecting port 102 at one end far away from the first liquid storage section 20, and the liquid absorbing section 50 is provided with a liquid absorbing port 103 at one end far away from the second liquid storage section 40.

In one embodiment, referring to fig. 1 to 3, at least two of the connection section 10, the first liquid storage section 20, the transition section 30, the second liquid storage section 40 and the liquid absorbing section 50 are in a unitary structure. The integral structure has higher structural strength and connection stability, and improves reliability.

Optionally, any two adjacent sections can be of an integral structure; namely, the connecting section 10 and the first liquid storage section 20 can be of an integral structure; alternatively, the first reservoir section 20 and the transition section 30 may be of unitary construction; alternatively, the transition section 30 and the second reservoir section 40 may be of unitary construction; alternatively, second reservoir section 40 and wicking section 50 may be of unitary construction.

Optionally, three sections which are connected in sequence at will can be of an integrated structure; namely, the connecting section 10, the first liquid storage section 20 and the transition section 30 can be of an integrated structure; alternatively, the first reservoir section 20, the transition section 30, and the second reservoir section 40 may be of unitary construction; alternatively, the transition section 30, the second fluid storage section 40, and the fluid intake section 50 may be of unitary construction.

Optionally, four sections which are connected in sequence at will can be of an integrated structure; namely, the connecting section 10, the first liquid storage section 20, the transition section 30 and the second liquid storage section 40 are of an integrated structure; alternatively, the first reservoir section 20, the transition section 30, the second reservoir section 40, and the wicking section 50 are of unitary construction.

Optionally, the connecting section 10, the first fluid storage section 20, the transition section 30, the second fluid storage section 40, and the fluid intake section 50 are integrally formed.

The integrated structure can be manufactured by an integrated forming process, for example, injection molding by a mold, and the integrated structure is not limited.

In the case where the portion of the non-integral structure is connected to the other portion, for example, in the case where the connecting section 10 and the first liquid storage section 20 are integrally formed, and the transition section 30 and the first liquid storage section 20 are integrally formed, the transition section 30 and the first liquid storage section 20 may be integrally connected and fixed by any feasible method, such as gluing, welding, etc. For other similar connections between two structures, reference is made to this method and no further description is given.

Alternatively, the connection section 10, the first liquid storage section 20, the transition section 30, the second liquid storage section 40 and the liquid absorption section 50 may be manufactured separately, and then the sections may be connected and fixed as a whole.

The materials of the connecting section 10, the first liquid storage section 20, the transition section 30, the second liquid storage section 40 and the liquid absorbing section 50 may be the same, for example, polypropylene, although any other feasible materials may be used. The materials of the connecting section 10, the first liquid storage section 20, the transition section 30, the second liquid storage section 40 and the liquid absorbing section 50 may not be the same or different, and may be set according to the needs, and the utility model is not limited.

Along the direction from the connecting section 10 to the liquid absorbing section 50, the first liquid storing section 20, the transition section 30, the second liquid storing section 40 and the liquid absorbing section 50 are all in a necking shape. In other words, the inner and outer diameters of each segment are tapered from the first reservoir segment 20 to the wicking segment 50 in the direction of the connector segment 10 toward the wicking segment 50. Wherein the minimum inner diameter of the first reservoir 20 is greater than the maximum inner diameter of the second reservoir 40. The arrangement is such that the reservoir 101 can form a plurality of sections of different volumes, i.e. the reservoir 101 comprises at least sections corresponding to the first reservoir section 20, the transition section 30, the second reservoir section 40 and the wicking section 50, the volumes of the sections being different. Since the minimum inner diameter of the first liquid storage section 20 is larger than the maximum inner diameter of the second liquid storage section 40, if the second liquid storage section 40 is extended to cover the position of the first liquid storage section 20, the volume of the extended part of the second liquid storage section 40 (i.e. the part of the first liquid storage section 20 is replaced) is also significantly smaller than the volume of the first liquid storage section 20 of the present utility model, so that the pipetting Tip head 100 of the present utility model can accommodate more sample liquid. In addition, the shape design of the necking is more compliant to the flowing property of liquid, is more beneficial to pipetting operation, and can reduce the phenomenon of liquid wall hanging as much as possible; the shape of the necking is convenient for demoulding operation when the mould is adopted for injection molding processing. In addition, referring to fig. 3 to 5, the inner diameter of the whole pipetting Tip head 100 is larger at the connection port 102, so that the pipetting Tip head 100 can be conveniently connected with the adapter 200 with larger size, and the inner diameter of the whole pipetting Tip head 100 is smaller at the pipetting port 103, so that the pipetting Tip head 100 can be conveniently extended into a small-mouth container to suck the sample liquid.

Referring to fig. 3 to 5, the connection section 10 is for detachably connecting with the adapter 200. Alternatively, the adapter 200 is inserted into the connection port 102 and tightly abuts against the inner wall 11 of the connection section 10, and connection fixation is achieved by friction force. Optionally, the connecting section 10 is made of elastic material, and the adapter 200 can expand the diameter of the connecting section 10, so as to enhance the connection stability and tightness. When the pipetting Tip head 100 needs to be replaced after pipetting is completed, the pipetting Tip head 100 can be pulled or pushed by force, so that the adapter 200 is withdrawn from the connection port 102, and the pipetting Tip head 100 is separated from the adapter 200.

The end of the adapter 200 remote from the pipetting Tip 100 is adapted to be connected to a pipetting mechanism (not shown) which is adapted to move the adapter 200 and provide a positive and negative driving force. When the pipetting mechanism drives the adapter 200 and the pipetting Tip head 100 to be at the initial position and provide negative pressure, the pipetting mechanism is communicated with the liquid storage cavity 101 through the adapter 200, so that the liquid storage cavity 101 is negative pressure, and the liquid suction port 103 of the liquid suction section 50 sucks sample liquid into the liquid storage cavity 101, thereby realizing liquid suction operation. When the pipetting mechanism drives the adapter 200 and the pipetting Tip 100 to move to the target position and provide positive pressure, the positive pressure acts on the sample liquid in the liquid storage cavity 101 to make the sample liquid be ejected from the liquid suction port 103 of the liquid suction section 50, so that the liquid ejection operation is realized, and the complete pipetting operation is realized.

The structural arrangement of the current Tip head is unreasonable, the single pipetting capacity is smaller, and when the pipetting operation with larger capacity is needed, the required capacity can be achieved only by pipetting for multiple times. Specifically, the current Tip corresponds to the second reservoir 40 and the pipette 50 of the present utility model, and the end of the second reservoir 40 away from the pipette 50 is connected to the adapter 200, and the volume thereof is very small, for example, the maximum volume of the current Tip applied to the automated pipetting operation is only 1ml. Even if the length of the current Tip is extended to be the same as that of the pipetting Tip 100 of the utility model, for example, the second liquid storage section 40 of the utility model is extended to be a new Tip along a straight line with the connection section 10, the capacity of the new Tip is smaller, and it is obvious that the liquid storage cavity 101 of the pipetting Tip 100 of the embodiment of the utility model has a larger volume at the first liquid storage section 20, the transition section 30, etc., for example, a maximum capacity of 5ml is realized.

In the embodiment of the utility model, by arranging the connecting section 10, the first liquid storage section 20, the transition section 30, the second liquid storage section 40 and the liquid absorption section 50, and arranging the first liquid storage section 20, the transition section 30, the second liquid storage section 40 and the liquid absorption section 50 in the direction from the connecting section 10 to the liquid absorption section 50, the first liquid storage section 20, the transition section 30, the second liquid storage section 40 and the liquid absorption section 50 are in a necking shape, the minimum inner diameter of the first liquid storage section 20 is larger than the maximum inner diameter of the second liquid storage section 40, a liquid storage cavity 101 with large volume (for example, the volume of the liquid storage cavity 101 at the first liquid storage section 20 is larger) can be designed, compared with the current Tip head, the volume of single liquid transfer can be obviously increased, and the required volume can be achieved by one liquid transfer operation, so that the liquid transfer efficiency can be improved.

In one embodiment, referring to fig. 3, the inner wall 21 of the first liquid storage section 20 has a first included angle with the axis 60, and the outer wall 22 of the first liquid storage section 20 has a second included angle with the axis 60, wherein the first included angle is smaller than or equal to the second included angle. If the first included angle is smaller than the second included angle, the die drawing angle can be formed, and the die can be conveniently removed when being processed by adopting an injection die.

In one embodiment, referring to fig. 3, one end of the transition section 30 is tangentially connected to the first reservoir section 20 and the other end of the transition section 30 is tangentially connected to the second reservoir section 40. Specifically, the inner diameter and the outer diameter of the end part of the transition section 30 connected with the first liquid storage section 20 are respectively equal to the inner diameter and the outer diameter of the end part of the first liquid storage section 20 far away from the connecting section 10; the inner diameter and the outer diameter of the end part of the transition section 30 connected with the second liquid storage section 40 are respectively equal to the inner diameter and the outer diameter of the end part of the second liquid storage section 40 far away from the liquid suction section 50; the arrangement is such that the transition section 30 is tangentially connected to the first and second fluid reservoir sections 20, 40, respectively.

Because the first liquid storage section 20, the transition section 30, the second liquid storage section 40 and the liquid absorption section 50 are all in the necking shape along the direction from the connecting section 10 to the liquid absorption section 50, the minimum inner diameter of the first liquid storage section 20 is larger than the maximum inner diameter of the second liquid storage section 40, and therefore, the transition section 30 is arranged for connection transition, and the two ends of the transition section 30 are respectively connected with the first liquid storage section 20 and the second liquid storage section 40 in a tangential manner, so that a smooth structure is formed, the phenomenon that stress concentration is easy to damage is avoided, the sample liquid can be sucked and discharged smoothly, and the liquid is prevented from remaining in the liquid storage cavity 101.

In one embodiment, referring to fig. 3, the transition section 30 includes a first arc portion 31 and a second arc portion 32, one end of the first arc portion 31 is tangentially connected to the first liquid storage section 20, one end of the second arc portion 32 is tangentially connected to the other end of the first arc portion 31, and the other end of the second arc portion 32 is tangentially connected to the second liquid storage section 40.

Specifically, the inner diameter and the outer diameter of the end part of the first arc part 31 connected with the first liquid storage section 20 are equal to the inner diameter and the outer diameter of the end part of the first liquid storage section 20 far away from the connecting section 10 respectively; the inner diameter and the outer diameter of the end part of the first arc part 31 connected with the second arc part 32 are respectively equal to the inner diameter and the outer diameter of the end part of the second arc part 32 far away from the second liquid storage section 40; the inner diameter and the outer diameter of the end portion of the second circular arc portion 32 connected with the second liquid storage section 40 are equal to the inner diameter and the outer diameter of the end portion of the second liquid storage section 40 far away from the liquid suction section 50, respectively, so that the first circular arc portion 31 is connected with the first liquid storage section 20 and the second circular arc portion 32 in a tangential manner, and the second circular arc portion 32 is connected with the first circular arc portion 31 and the second liquid storage section 40 in a tangential manner.

In the cross section (longitudinal section) passing through the axis 60, the contour lines of the first arc portion 31 and the second arc portion 32 are both arcs, and the radian of the arcs is not limited, and the radius is not limited.

Because the first liquid storage section 20, the transition section 30, the second liquid storage section 40 and the liquid absorption section 50 are all in the necking shape along the direction from the connecting section 10 to the liquid absorption section 50, the minimum inner diameter of the first liquid storage section 20 is larger than the maximum inner diameter of the second liquid storage section 40, and therefore, the transition section 30 is arranged for connection transition, the first circular arc part 31 is respectively connected with the first liquid storage section 20 and the second circular arc part 32 tangentially, the second circular arc part 32 is respectively connected with the first circular arc part 31 and the second liquid storage section 40 tangentially, a smooth structure is formed, the phenomenon that the stress is concentrated and the damage is easy is avoided, the sample liquid can be smoothly sucked and discharged, and the liquid is prevented from remaining in the liquid storage cavity 101.

Further, the first arc portion 31 protrudes away from the axis 60, the center of the circle is located at the side facing the axis 60, and the second arc portion 32 protrudes toward the axis 60, and the center of the circle is located at the side facing away from the axis 60. By the arrangement, the whole transition section 30 is in a necking shape, and meanwhile, the transition section is smooth and smooth, and liquid sucking and liquid discharging operations are facilitated.

In an embodiment, referring to fig. 3, the inner wall 41 of the second liquid storage section 40 has a third included angle with the axis 60, and the outer wall 42 of the second liquid storage section 40 has a fourth included angle with the axis 60, and the third included angle is smaller than or equal to the fourth included angle. If the third included angle is smaller than the fourth included angle, the die drawing angle can be formed, and the die can be conveniently removed when being processed by adopting an injection die.

In one embodiment, referring to fig. 3, the inner wall 51 of the liquid absorbing section 50 has a fifth included angle with the axis 60, and the outer wall 52 of the liquid absorbing section 50 has a sixth included angle with the axis 60, and the fifth included angle is less than or equal to the sixth included angle. If the fifth included angle is smaller than the sixth included angle, the die drawing angle can be formed, and the die can be conveniently removed when being processed by adopting an injection die.

In an embodiment, referring to fig. 3, an included angle between the inner wall 21 of the first liquid storage section 20 and the axis 60 is a first included angle, an included angle between the inner wall 41 of the second liquid storage section 40 and the axis 60 is a third included angle, and the third included angle is greater than or equal to the first included angle. If the third included angle is greater than the first included angle, the arrangement is such that the necking degree of the second liquid storage section 40 is greater than that of the first liquid storage section 20, the liquid suction section 50 with smaller size can be arranged at one end, away from the transition section 30, of the second liquid storage section 40, and meanwhile, the necking degree of the first liquid storage section 20 is smaller, and a larger volume can be formed to increase the capacity of the liquid storage cavity 101.

Optionally, the outer wall 22 of the first liquid storage section 20 forms a second angle with the axis 60, the outer wall 42 of the second liquid storage section 40 forms a fourth angle with the axis 60, and the fourth angle is greater than or equal to the second angle. By this arrangement, the difference in wall thickness between the first liquid storage section 20 and the second liquid storage section 40 is small, and the structure is ensured while the reduced shape is formed.

In one embodiment, referring to fig. 3, the inner wall 41 of the second liquid storage section 40 has a third included angle with the axis 60, and the inner wall 51 of the liquid absorbing section 50 has a fifth included angle with the axis 60, and the fifth included angle is larger than the third included angle. So set up for the throat degree of imbibition section 50 is bigger than second stock solution section 40, can make the very little that the size that the pointed end of imbibition section 50 (i.e. the one end of keeping away from second stock solution section 40) contracts, conveniently gets into imbibition and spit liquid in the osculum container, can make the volume of first stock solution section 20 also great simultaneously to increase the capacity of stock solution chamber 101.

In one embodiment, referring to fig. 3 to 5, the inner wall 11 of the connecting section 10 is flush and coplanar with the inner wall 21 of the first liquid storage section 20; in other words, the included angle between the inner wall 11 of the connecting section 10 and the axis 60 is equal to the included angle (i.e. the first included angle) between the inner wall of the first liquid storage section 20 and the axis 50, and since the first liquid storage section 20 is in the shape of a necking, the connecting section 10 is also in the shape of a necking, and the necking degrees of the first liquid storage section 20 and the connecting section 10 are the same. The inner diameter of the connecting section 10 at the end connected to the first liquid storage section 20 is equal to the inner diameter of the first liquid storage section 20 at the end remote from the transition section 30. By the arrangement, the adapter 200 can partially extend into the first liquid storage section 20, so that the mounting of the pipetting Tip head 100 and the adapter 200 can be facilitated, and the mounting error tolerance is increased. In addition, the connection section 10 and the first liquid storage section 20 are also conveniently manufactured into an integrated structure through an integrated molding process.

In one embodiment, referring to fig. 3 to 5, the outer wall 12 of the connection section 10 is flush and coplanar with the outer wall 22 of the first liquid storage section 20; in other words, the included angle between the outer wall of the connecting section 10 and the axis 60 is equal to the included angle (i.e. the second included angle) between the outer wall of the first liquid storage section 20 and the axis 60. The outer diameter of the end of the connecting section 10 that connects with the first reservoir section 20 is equal to the outer diameter of the end of the first reservoir section 20 that is remote from the transition section 30. By means of the arrangement, the connecting section 10 and the first liquid storage section 20 can be manufactured into an integrated structure through an integrated forming process.

In embodiments where the connecting segment 10 and the inner and outer walls of the first reservoir segment 20 are flush and coplanar, the connecting segment 10 may also be considered as part of the first reservoir segment 20.

Alternatively, the connecting section 10 may be non-necked, for example, may be straight, i.e., the inner wall of the connecting section 10 may be generally parallel to the axis 60, and the outer wall of the connecting section 10 may be generally parallel to the axis 60.

In other embodiments, the inner and outer walls of the connecting section 10 and the first reservoir section 20 may not be flush and coplanar, for example, the wall thickness of the connecting section 10 may be thicker and the strength may be enhanced to facilitate connection with the adapter 200. The connecting segment 10 may also have any other feasible shape and configuration. Alternatively, the inner diameter of the connection section 10 may be larger than the maximum inner diameter of the first liquid storage section 20, so that a step surface is formed at the connection position between the connection section 10 and the first liquid storage section 20, and the step surface can avoid the adaptor 200 from penetrating into the first liquid storage section 20 when being inserted into the pipetting Tip head 100, and can avoid the sample liquid from polluting the adaptor 200.

It should be understood that the connection section 10 mainly serves to connect with the adapter 200, and its shape, structure, etc. should be adapted to the adapter.

Alternatively, referring to fig. 1 to 3, the volume of the liquid storage chamber 101 is 4ml to 6ml; specifically, the volume of the liquid storage chamber 101 may be 4ml, 4.5ml, 5ml, 5.5ml, 6ml, etc. Optionally, the connecting section 10 has an inner diameter of 10mm to 14mm at the end remote from the first reservoir section 20; specifically, the inner diameter may be 10mm, 11mm, 12mm, 13mm, 14mm, etc. Optionally, the end of the wicking segment 50 remote from the second reservoir segment 40 has an inner diameter of 0.8mm to 1.2mm; specifically, the inner diameter may be 0.8mm, 0.9mm, 1.0mm, 1.1mm, 1.2mm, etc. Alternatively, the length of the pipetting Tip head 100 is 124 mm.+ -. 0.2mm. By setting at least one of the above parameters, the need for a large volume reservoir 101 is fulfilled.

In one embodiment, referring to fig. 1 and 3 to 5, a chamfer 13 is formed between an end surface of the connecting section 10, which is far from the first liquid storage section 20, and the inner wall 11. The chamfer 13 is provided at the entrance of the connection port 102 to facilitate guiding the insertion of the adapter 200 into the connection segment 10. The specific dimensional parameters of the chamfer 13 are not limited.

Alternatively, referring to fig. 1 and 3, an annular groove 16 may be formed in the inner wall 11 of the connecting section 10 near the chamfer 13, and the annular groove 16 is concave relative to the inner wall 11 of the connecting section 10 and is annular in shape. The annular groove 16 has the effect of facilitating demolding, and is beneficial to the detachment of the Tip head from the female mold cavity.

In one embodiment, referring to fig. 1, 4 and 5, the outer wall 12 of the connecting section 10 is provided with a reinforcement. The reinforcing portion serves to reinforce the structural strength of the connection section 10 so that the connection section 10 is stably connected with the adapter 200, and the specific structure of the reinforcing portion may not be limited.

Optionally, the reinforcement portion includes an annular protrusion 14 extending along the circumference of the connection section 10 and connected end to end, the annular protrusion 14 being disposed on the outer wall 12 of the end of the connection section 10 remote from the first reservoir section 20 and protruding with respect to the outer wall 12 of the connection section 10. The annular protrusion 14 is arranged, so that the end part of the connecting section 10, which is far away from the first liquid storage section 20, is not easy to crack when the adapter 200 is extruded, and the structural strength is improved.

Optionally, the reinforcing part further includes a plurality of reinforcing ribs 15 extending along the axial direction of the connection section 10, the plurality of reinforcing ribs 15 are arranged along the circumferential direction of the connection section 10 and are arranged at equal intervals on the outer wall 12 of the connection section 10, and one ends of the plurality of reinforcing ribs 15 are connected with the annular protrusion 14. The plurality of reinforcing ribs 15 further improve the structural strength of the connecting section 10, so that the connecting section 10 and the adapter 200 can be firmly connected, looseness is not easy, and the connecting section 10 cannot be damaged due to structural failure.

The annular protrusion 14 and the plurality of reinforcing ribs 15 may be integrally formed, and both may be integrally formed with the connection section 10 at the same time, so as to improve structural strength and connection stability.

In addition, when the Tip head 100 is completely pipetted and is required to be placed on the well plate, or an empty Tip head is required to be placed in the well plate, the reinforcement part may be placed on a support structure on the well plate, so that the well plate plays a supporting and fixing role on the Tip head.

Referring to fig. 1 to 5, an embodiment of the present utility model further provides a pipetting device, which includes a pipetting mechanism, an adapter 200 and the pipetting Tip 100 of any of the foregoing embodiments, wherein one end of the adapter 200 is detachably connected to the pipetting mechanism, and the other end of the adapter 200 is detachably connected to the connection section 10 of the pipetting Tip 100.

The pipetting mechanism provides positive and negative pressure to control pipetting Tip head 100 for pipetting and pipetting operations. The detachable connection between the adapter 200 and the pipetting mechanism may include any feasible connection manner such as screw connection, clamping connection, magnetic attraction, etc., and the detachable connection between the connection section 10 of the pipetting Tip 100 and the adapter 200 may be clamping connection, for example, the aforementioned adapter 200 is inserted into the connection port 102 of the connection section 10 to generate extrusion with the inner wall 11 of the connection section 10, so as to realize stable connection by friction force. Of course, any other feasible manner may be used, and no limitation is imposed.

According to the pipetting device provided by the embodiment of the utility model, by adopting the pipetting Tip 100 of the embodiment of the utility model, compared with the current Tip, the pipetting Tip 100 has the advantages that the capacity of single pipetting can be obviously increased, the required capacity can be achieved by one pipetting operation, and the pipetting efficiency can be improved by arranging the connecting section 10, the first liquid storage section 20, the transition section 30, the second liquid storage section 40 and the pipetting section 50, and the first liquid storage section 20, the transition section 30, the second liquid storage section 40 and the pipetting section 50 are all in the necking shape along the direction of the connecting section 10 to the pipetting section 50, wherein the minimum inner diameter of the first liquid storage section 20 is larger than the maximum inner diameter of the second liquid storage section 40, and the liquid storage cavity 101 with large capacity (for example, the capacity of the liquid storage cavity 101 at the first liquid storage section 20 is larger) can be designed.

In addition, the pipetting device may further include a handling mechanism, such as a multi-axis mechanical arm or an XYZ moving assembly, capable of driving the pipetting mechanism to move, so that the pipetting mechanism can be moved to a designated position to prick and pick up the pipetting Tip 100 through the adapter 200, and the pipetting mechanism can be moved to a working position to perform pipetting, and the like by using the pipetting Tip 100, thereby increasing flexibility of the pipetting device and expanding working space of the pipetting device.

In the description of the embodiments of the present utility model, it should be noted that, the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," "outer," and the like refer to the orientation or positional relationship described based on the drawings, which are merely for convenience of description and simplification of the description, and do not indicate or imply that the apparatus or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and therefore should not be construed as limiting the present utility model.

The above disclosure is only a preferred embodiment of the present utility model, and it should be understood that the scope of the utility model is not limited thereto, but all or part of the procedures for implementing the above embodiments can be modified by one skilled in the art according to the scope of the appended claims.

Claims (16)

1. The pipetting Tip head is characterized by being in a rotationally symmetrical structure along an axis and enclosing to form liquid storage cavities penetrating through two ends of the axis, wherein the liquid storage cavities are used for storing liquid;

the pipetting Tip head comprises a connecting section, a first liquid storage section, a transition section, a second liquid storage section and a liquid suction section which are sequentially connected along the axial direction, the first liquid storage section, the transition section, the second liquid storage section and the liquid suction section are all in a necking shape, the minimum inner diameter of the first liquid storage section is larger than the maximum inner diameter of the second liquid storage section, the connecting section is used for being detachably connected with an adapter, and the liquid suction section is used for sucking or spitting liquid.

2. The pipetting Tip of claim 1 wherein the inner wall of the first reservoir has a first angle with the axis and the outer wall of the first reservoir has a second angle with the axis, the first angle being less than or equal to the second angle.

3. The pipetting Tip head of claim 1 wherein one end of the transition section is tangentially connected to the first reservoir section and the other end of the transition section is tangentially connected to the second reservoir section.

4. A pipetting Tip head as recited in claim 3 wherein the transition section comprises a first arcuate portion and a second arcuate portion, one end of the first arcuate portion being tangentially connected to the first reservoir section, one end of the second arcuate portion being tangentially connected to the other end of the first arcuate portion, the other end of the second arcuate portion being tangentially connected to the second reservoir section.

5. The pipetting Tip head of claim 4 wherein the first rounded portion projects away from the axis and the second rounded portion projects toward the axis.

6. The pipetting Tip of any one of claims 1-5 wherein an inner wall of the second reservoir section has a third angle with the axis and an outer wall of the second reservoir section has a fourth angle with the axis, the third angle being less than or equal to the fourth angle.

7. The pipetting Tip of any one of claims 1-5 wherein the inner wall of the wick section has a fifth angle with the axis and the outer wall of the wick section has a sixth angle with the axis, the fifth angle being less than or equal to the sixth angle.

8. The pipetting Tip of any one of claims 1-5 wherein the angle between the inner wall of the first reservoir section and the axis is a first angle and the angle between the inner wall of the second reservoir section and the axis is a third angle, the third angle being greater than or equal to the first angle.

9. The pipetting Tip of any one of claims 1-5 wherein the inner wall of the second reservoir section has a third angle with the axis and the inner wall of the wicking section has a fifth angle with the axis, the fifth angle being greater than the third angle.

10. The pipetting Tip of any one of claims 1-5 wherein the angle of the inner wall of the connecting section to the axis is equal to the angle of the inner wall of the first reservoir section to the axis; and/or the included angle between the outer wall of the connecting section and the axis is equal to the included angle between the outer wall of the first liquid storage section and the axis;

and/or, the inner diameter of the connecting section is larger than the maximum inner diameter of the first liquid storage section.

11. The pipetting Tip according to any one of claims 1-5 wherein the volume of the reservoir is 4ml-6ml; and/or the inner diameter of the end part of the connecting section far away from the first liquid storage section is 10mm-14mm; and/or the inner diameter of the end part of the liquid absorbing section far away from the second liquid storage section is 0.8mm-1.2mm.

12. The pipetting Tip of any one of claims 1-5 wherein at least two of the connecting section, the first reservoir section, the transition section, the second reservoir section, and the pipetting section are of unitary construction.

13. The pipetting Tip according to any one of claims 1-5 wherein a chamfer is formed between an end surface of the connecting section distal from the first reservoir section and an inner wall; the outer wall of the connecting section is provided with a reinforcing part, and the reinforcing part is used for reinforcing the structural strength of the connecting section so that the connecting section is stably connected with the adapter.

14. The pipetting Tip head of claim 13 wherein the reinforcement portion comprises an annular projection extending circumferentially of the connecting section and connected end-to-end, the annular projection being disposed on and protruding relative to an outer wall of an end of the connecting section remote from the first reservoir section;

the reinforcing part further comprises a plurality of reinforcing ribs extending along the axial direction of the connecting section, the reinforcing ribs are distributed along the circumferential direction of the connecting section and are arranged on the outer wall of the connecting section at equal interval, and one ends of the reinforcing ribs are connected with the annular protrusions.

15. A pipetting device comprising a pipetting mechanism, an adapter and a pipetting Tip as recited in any one of claims 1-14, one end of the adapter being removably connected to the pipetting mechanism and the other end of the adapter being removably connected to a connecting section of the pipetting Tip.

16. The pipetting device of claim 15, further comprising a handling mechanism coupled to the pipetting mechanism for moving the pipetting mechanism.

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