CN219291217U - Novel stirring device for preparing solid lipid nano particles - Google Patents
Novel stirring device for preparing solid lipid nano particles Download PDFInfo
- Publication number
- CN219291217U CN219291217U CN202320237367.XU CN202320237367U CN219291217U CN 219291217 U CN219291217 U CN 219291217U CN 202320237367 U CN202320237367 U CN 202320237367U CN 219291217 U CN219291217 U CN 219291217U
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- China
- Prior art keywords
- fixedly connected
- connecting plate
- stirring device
- gear
- solid lipid
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- 238000003756 stirring Methods 0.000 title claims abstract description 63
- 239000002047 solid lipid nanoparticle Substances 0.000 title claims abstract description 20
- 244000309464 bull Species 0.000 claims description 14
- 238000007599 discharging Methods 0.000 claims description 7
- 238000001914 filtration Methods 0.000 claims description 7
- 239000011148 porous material Substances 0.000 claims description 4
- 238000007789 sealing Methods 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 239000000463 material Substances 0.000 abstract description 17
- 239000002105 nanoparticle Substances 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 7
- 238000002360 preparation method Methods 0.000 abstract description 4
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 abstract description 3
- 238000002156 mixing Methods 0.000 abstract description 3
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 2
- 238000013329 compounding Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 229910052709 silver Inorganic materials 0.000 description 2
- 239000004332 silver Substances 0.000 description 2
- 239000012257 stirred material Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000007664 blowing Methods 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
Images
Classifications
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P70/00—Climate change mitigation technologies in the production process for final industrial or consumer products
- Y02P70/10—Greenhouse gas [GHG] capture, material saving, heat recovery or other energy efficient measures, e.g. motor control, characterised by manufacturing processes, e.g. for rolling metal or metal working
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- Mixers Of The Rotary Stirring Type (AREA)
Abstract
The utility model relates to the technical field of nanoparticle preparation and discloses a novel stirring device for preparing solid lipid nanoparticles, which comprises a connecting plate, wherein a first supporting rod is fixedly connected to the right side of the top of the connecting plate, a motor is fixedly connected to the top of the first supporting rod, a first rotating rod is fixedly connected to the output end of the motor, a first gear is fixedly connected to the left end of the first rotating rod, a first belt pulley is fixedly connected to the middle of the first rotating rod, and a second supporting rod is fixedly connected to the left side of the top of the connecting plate. According to the utility model, materials are placed in the stirring barrel, the starting motor is matched with the first rotating rod to drive the first gear, the first belt pulley, the second gear, the stirring barrel, the first belt pulley, the belt, the second belt pulley and the second rotating rod, so that the stirring paddle and the stirring barrel are in opposite directions to stir the materials, the stirring is more uniform, the mixing effect is good, and the using effect of silver nano particles is not influenced.
Description
Technical Field
The utility model relates to the technical field of nanoparticle preparation, in particular to a novel stirring device for preparing solid lipid nanoparticles.
Background
The solid lipid nanoparticle is a new generation submicron drug delivery system developed in the early 90 th century, has the advantages of being capable of controlling drug release, avoiding degradation or leakage of the drug, good targeting property and the like, and needs to be mixed by adding other liquid during the preparation process, and stirring of materials is needed during the process.
Because solid lipid nanoparticle is very little, most of the present equipment is only through the stirring rake stirring when using, and the compounding effect is not enough, is difficult to guarantee the stirring, and then influences silver nanoparticle's result of use.
Disclosure of Invention
The utility model aims to solve the defects in the prior art, and provides a novel stirring device for preparing solid lipid nanoparticles.
In order to achieve the above purpose, the present utility model adopts the following technical scheme: the utility model provides a novel stirring device for solid lipid nanoparticle preparation, includes the connecting plate, the first bracing piece of top right side fixedly connected with of connecting plate, the top fixedly connected with motor of first bracing piece, the first bull stick of output fixedly connected with of motor, the first gear of left end fixedly connected with of first bull stick, the first belt pulley of middle part fixedly connected with of first bull stick, the top left side fixedly connected with second bracing piece of connecting plate, the top fixedly connected with inlet pipe of second bracing piece, the right-hand member rotation of inlet pipe is connected with the agitator, the right side fixedly connected with second gear of agitator, the middle part of agitator is provided with the second bull stick, the right-hand member of second bull stick runs through agitator and second gear and fixedly connected with second belt pulley, second belt pulley and first belt pulley are connected by the belt, equidistance fixedly connected with stirring rake on the second bull stick.
As a further description of the above technical solution:
the middle part of connecting plate is provided with the filtration pore, the top middle part fixedly connected with baffle of connecting plate.
As a further description of the above technical solution:
the bottom four corners of connecting plate all fixedly connected with pillar, the bottom fixedly connected with bottom plate of pillar, the top middle part of bottom plate is provided with the collecting box, the front side fixedly connected with handle of collecting box.
As a further description of the above technical solution:
the top left front end fixedly connected with switch of connecting plate, switch and motor electric connection.
As a further description of the above technical solution:
the top of inlet pipe intercommunication has the feeder hopper.
As a further description of the above technical solution:
and the four corners of the bottom plate are fixedly connected with anti-slip pads.
As a further description of the above technical solution:
the bottom of the stirring barrel is communicated with a discharging pipe, and the bottom of the stirring barrel is provided with a sealing cover.
As a further description of the above technical solution:
the first gear is in meshed connection with the second gear.
The utility model has the following beneficial effects:
1. according to the utility model, materials are placed in the stirring barrel, the starting motor is matched with the first rotating rod to drive the first gear, the first belt pulley, the second gear, the stirring barrel, the first belt pulley, the belt, the second belt pulley and the second rotating rod, so that the stirring paddle and the stirring barrel are in opposite directions to stir the materials, the stirring is more uniform, and the mixing effect is good.
2. According to the utility model, the stirred materials drop to the filtering holes through the discharging pipe to be filtered, and the filtered materials are collected through the collecting box, so that the size of the nano particles is more uniform, and the using effect of the silver nano particles is not affected.
Drawings
FIG. 1 is a front view of a stirring device for preparing novel solid lipid nanoparticles;
FIG. 2 is a perspective view of a stirring device for preparing novel solid lipid nanoparticles;
fig. 3 is a cross-sectional view of a stirring device for preparing novel solid lipid nanoparticles according to the present utility model.
Legend description:
1. a connecting plate; 2. a first support bar; 3. a motor; 4. a first rotating lever; 5. a first pulley; 6. a second pulley; 7. a first gear; 8. a second gear; 9. a stirring barrel; 10. a feed pipe; 11. a discharge pipe; 12. sealing cover; 13. a second support bar; 14. a baffle; 15. a collection box; 16. a handle; 17. a support post; 18. a bottom plate; 19. an anti-slip pad; 20. a switch; 21. a feed hopper; 22. filtering holes; 23. a belt; 24. stirring paddles; 25. and a second rotating rod.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1-3, one embodiment provided by the present utility model is: the novel stirring device for preparing solid lipid nanoparticles comprises a connecting plate 1, a first supporting rod 2 is fixedly connected to the right side of the top of the connecting plate 1, a motor 3 is fixedly connected to the top of the first supporting rod 2, a first rotating rod 4 is fixedly connected to the output end of the motor 3, a first gear 7 is fixedly connected to the left end of the first rotating rod 4, a first belt pulley 5 is fixedly connected to the middle part of the first rotating rod 4, the motor 3 is matched with the first rotating rod 4 to drive the first gear 7 and the first belt pulley 5 to rotate, a second supporting rod 13 is fixedly connected to the left side of the top of the connecting plate 1, a feeding pipe 10 is fixedly connected to the top of the second supporting rod 13, materials are placed into a stirring barrel 9 through the feeding pipe 10, a stirring barrel 9 is rotatably connected to the right end of the feeding pipe 10, a second gear 8 is fixedly connected to the right side of the stirring barrel 9, the first gear 7 drives the second gear 8 to rotate, the stirring barrel 9 is further rotated by the second gear 8, a second rotating rod 25 is arranged in the middle of the stirring barrel 9, the right end of the second rotating rod 25 penetrates through the stirring barrel 9 and the second gear 8 and is fixedly connected with a second belt pulley 6, the second belt pulley 6 is connected with a first belt pulley 5 by a belt 23, stirring paddles 24 are fixedly connected to the second rotating rod 25 at equal intervals, the second belt pulley 6 is driven to rotate by the first belt pulley 5 in cooperation with the belt 23, the second belt pulley 6 drives the second rotating rod 25 to enable the stirring paddles 24 to stir materials in the opposite direction with the stirring barrel 9, when the stirring barrel 9 is used, the materials are placed into the stirring barrel 9 through a feed hopper 21 and pass through a feed pipe 10, a switch 20 is used for starting a motor 3 to drive a first gear 7 and the first belt pulley 5 to rotate by matching with the first rotating rod 4, the first gear 7 drives the second gear 8 to rotate, the second gear 8 is further driven by the second gear 8 to rotate, simultaneously, the first belt pulley 5 is matched with the belt 23 to drive the second belt pulley 6 to rotate, the second belt pulley 6 drives the second rotating rod 25 to enable the stirring paddle 24 to stir materials in the opposite direction to the stirring barrel 9, the stirred materials drop to the filter holes 22 through the discharging pipe 11 to be filtered, and the filtered materials are collected through the collecting box 15, so that the mixing effect is good, the stirring is uniform, and the using effect of silver nano particles is not influenced.
The middle part of connecting plate 1 is provided with filtration pore 22, the top middle part fixedly connected with baffle 14 of connecting plate 1, filtration pore 22 filters the nanoparticle that stirs, make its size more even, baffle 14 is when avoiding the blowing, the nanoparticle splashes to outside, keep off it, the equal fixedly connected with pillar 17 in four corners in bottom of connecting plate 1, the bottom fixedly connected with bottom plate 18 of pillar 17, the top middle part of bottom plate 18 is provided with collecting box 15, collecting box 15's front side fixedly connected with handle 16, be used for collecting the nanoparticle that stirs, connecting plate 1's top left side front end fixedly connected with switch 20, switch 20 and motor 3 electric connection, be used for controlling the start and stop of motor 3, the top intercommunication of inlet pipe 10 has feeder hopper 21, put into the material through feeder hopper 21, the equal fixedly connected with slipmat 19 in bottom four corners of bottom plate 18, the friction between increasing device and the ground is provided with discharging pipe 11 in the bottom intercommunication of agitator 9, open sealed lid 12, discharge pipe 11 discharges the material through discharging pipe 11, first gear 7 and second gear 7 drive gear 8 and rotate through the gear 8 and carry out the meshing.
Working principle: put into agitator 9 with the material through feeder hopper 21 through inlet pipe 10, drive first gear 7 and first belt pulley 5 through switch 20 start motor 3 cooperation first bull stick 4 and rotate in going, first gear 7 drives second gear 8 and rotates, second gear 8 and then bring agitator 9 to rotate, first belt pulley 5 cooperates belt 23 to drive second belt pulley 6 simultaneously and rotates, second belt pulley 6 drives second bull stick 25 and makes stirring rake 24 and agitator 9 opposite direction stir the material, the material that stirs drops to filtering aperture 22 through discharging pipe 11 and filters, filterable material is collected it through collecting box 15, thereby the compounding is effectual, stir evenly, do not influence silver nanoparticle's result of use.
Finally, it should be noted that: the foregoing description is only illustrative of the preferred embodiments of the present utility model, and although the present utility model has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described, or equivalents may be substituted for elements thereof, and any modifications, equivalents, improvements or changes may be made without departing from the spirit and principles of the present utility model.
Claims (8)
1. Novel stirring device for preparing solid lipid nano particles, comprising a connecting plate (1), and being characterized in that: the utility model discloses a stirring device for a water turbine, including connecting plate (1), first bracing piece (2) of top right side fixedly connected with of connecting plate (1), the top fixedly connected with motor (3) of first bracing piece (2), the output fixedly connected with first bull stick (4) of motor (3), the left end fixedly connected with first gear (7) of first bull stick (4), the middle part fixedly connected with first belt pulley (5) of first bull stick (4), the top left side fixedly connected with second bracing piece (13) of connecting plate (1), the top fixedly connected with inlet pipe (10) of second bracing piece (13), the right-hand member rotation of inlet pipe (10) is connected with agitator (9), the right side fixedly connected with second gear (8) of agitator (9), the middle part of agitator (9) is provided with second bull stick (25), the right-hand member of second bull stick (25) runs through agitator (9) and second gear (8) and fixedly connected with second belt pulley (6), second belt pulley (6) and first belt pulley (5) are connected with second bull stick (24) by second belt pulley (23), on the equidistance is connected with agitator (24).
2. The stirring device for preparing novel solid lipid nanoparticles according to claim 1, wherein: the middle part of connecting plate (1) is provided with filtration pore (22), the top middle part fixedly connected with baffle (14) of connecting plate (1).
3. The stirring device for preparing novel solid lipid nanoparticles according to claim 1, wherein: the novel solar energy collecting device is characterized in that the four corners of the bottom of the connecting plate (1) are fixedly connected with supporting columns (17), the bottom of each supporting column (17) is fixedly connected with a bottom plate (18), a collecting box (15) is arranged in the middle of the top end of each bottom plate (18), and the front side of each collecting box (15) is fixedly connected with a handle (16).
4. The stirring device for preparing novel solid lipid nanoparticles according to claim 1, wherein: the front end of the left side of the top of the connecting plate (1) is fixedly connected with a switch (20), and the switch (20) is electrically connected with the motor (3).
5. The stirring device for preparing novel solid lipid nanoparticles according to claim 1, wherein: the top of the feed pipe (10) is communicated with a feed hopper (21).
6. A novel stirring device for preparing solid lipid nanoparticles according to claim 3, characterized in that: and the four corners of the bottom plate (18) are fixedly connected with anti-slip pads (19).
7. The stirring device for preparing novel solid lipid nanoparticles according to claim 1, wherein: the bottom of the stirring barrel (9) is communicated with a discharging pipe (11), and the bottom is provided with a sealing cover (12).
8. The stirring device for preparing novel solid lipid nanoparticles according to claim 1, wherein: the first gear (7) is connected with the second gear (8) in a meshed mode.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320237367.XU CN219291217U (en) | 2023-02-17 | 2023-02-17 | Novel stirring device for preparing solid lipid nano particles |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320237367.XU CN219291217U (en) | 2023-02-17 | 2023-02-17 | Novel stirring device for preparing solid lipid nano particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219291217U true CN219291217U (en) | 2023-07-04 |
Family
ID=86954286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320237367.XU Active CN219291217U (en) | 2023-02-17 | 2023-02-17 | Novel stirring device for preparing solid lipid nano particles |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219291217U (en) |
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2023
- 2023-02-17 CN CN202320237367.XU patent/CN219291217U/en active Active
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