CN219217971U - High-density fermentation equipment - Google Patents

High-density fermentation equipment Download PDF

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Publication number
CN219217971U
CN219217971U CN202223144571.1U CN202223144571U CN219217971U CN 219217971 U CN219217971 U CN 219217971U CN 202223144571 U CN202223144571 U CN 202223144571U CN 219217971 U CN219217971 U CN 219217971U
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pipe
tank body
connecting pipe
blade
air
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请求不公布姓名
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Jiangxi Weibolai Biopharmaceutical Co ltd
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Jiangxi Weibolai Biopharmaceutical Co ltd
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02WCLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
    • Y02W30/00Technologies for solid waste management
    • Y02W30/40Bio-organic fraction processing; Production of fertilisers from the organic fraction of waste or refuse

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Abstract

The utility model discloses high-density fermentation equipment, which comprises a stirring shaft, a first blade and a second blade, wherein the first blade is a straight blade which is inclined downwards, so that the stirred liquid can be turned up and down, and air or/and oxygen is uniformly distributed in feed liquid; the second paddle is spiral upwards along the stirring shaft spiral for stirring is more abundant, and the mixing effect is better, and can promote dissolved oxygen, is favorable to fermentation reaction's going on, and spiral paddle can also reduce the injury to the thallus. According to the utility model, the main connecting pipe and the branch connecting pipes are mutually perpendicular and arranged at the bottom of the tank body, the end parts of the branch connecting pipes are closed, the pipe bodies of the branch connecting pipes are uniformly provided with the air outlets, and after the air is introduced into the main connecting pipes, the air can be discharged from the air outlets on the branch connecting pipes, so that the oxygen can be more uniformly and more dispersed and more fully supplied for the thalli, the fermentation process is facilitated, and the influence on the fermentation process caused by the fact that the oxygen cannot be obtained at certain corners of the tank body is avoided.

Description

High-density fermentation equipment
Technical Field
The utility model relates to a high-density fermentation device.
Background
The general fermentation is mainly based on natural growth characteristics of wild strains or conventional engineering strains, and the fermentation is propagated and proliferated in a nutrient solution with a certain concentration, so that raw materials are converted into products required by human beings through a specific way. In industrial production, this mode tends to bring about some drawbacks: for example, the water consumption is large, the number of effective strains in unit volume and the product content are small, and the internal space of the fermentation device can not be fully utilized. Thus, a High-density fermentation technology (High-cell-density cultivation, HCDC) has been developed, and the specific productivity (yield of the product per unit volume per unit time) of the product is finally improved mainly by increasing the fermentation density of the cells.
However, in practical operation, high-density fermentation is often realized only in small-sized equipment due to equipment limitation, and cannot be applied in large-scale industrialization, and the following restriction factors mainly exist:
(1) When strains in large-scale equipment are piled up at high density, the strains below the large-scale equipment cannot effectively obtain oxygen to cause death; in addition, strains created by synthetic biology are used in fermentation, and if the dissolved oxygen concentration is not guaranteed, the reaction efficiency is affected; (2) The strain can generate carbon dioxide, heat and the like in the catalytic reaction process, the gas, the heat and the like can not be discharged in time, and the strain death and the strain breakage can be caused by accumulation; (3) The equipment is large in volume, and cannot be fully and uniformly stirred, so that the data of the sampling points cannot be comprehensively represented; (4) In order to realize uniform stirring, only the number or the diameter of stirring paddles is increased, the rotation speed of the stirring paddles is increased, and the thalli are easily damaged physically.
How to design the structure of high-density fermentation equipment is a problem to be solved.
Disclosure of Invention
In view of the above, the present utility model provides a high-density fermentation apparatus to overcome the drawbacks of the prior art.
In order to achieve the above object, the present utility model provides the following technical solutions:
the first object of the utility model is to provide a high-density fermentation device, which comprises a tank body, a stirring structure and an air supply system, wherein the stirring structure and the air supply system are respectively connected with the tank body;
the stirring structure is located inside the tank body, the stirring structure comprises a stirring shaft, a first blade and a second blade, the first blade and the second blade are respectively connected with the stirring shaft, the first blade is located on the upper portion of the second blade, the first blade is a straight blade which is inclined downwards, the stirred feed liquid can be enabled to roll up and down, the feed liquid on the upper layer is enabled to be quickly mixed with the feed liquid on the lower layer, air or/and oxygen are evenly distributed in the feed liquid, tangential flow (tangential flow is unfavorable for mixing, tangential flow is fluid swirling, fluid is mainly discharged from the blades to the periphery, the fluid quantity sucked to the blade area is very small, and the fluid mixing effect in the vertical direction is very poor).
In some preferred modes, the second paddle is spiral, and the second paddle is upwards spiral along the stirring shaft, so that the stirring of the paddles is more sufficient, the full contact mixing of materials is facilitated, dissolved oxygen can be promoted, and the damage to thalli can be reduced due to the spiral structure.
In some preferred forms, the air supply system includes an air outlet member, an air supply tube, a sterilizer, and an air pump, the air outlet member being connected to the air supply tube, the air supply tube being connected to the sterilizer, the sterilizer also being connected to the air pump. In some preferred forms, the air outlet member is provided with an air outlet.
In some preferred embodiments, the gas outlet means comprises a total connection tube or/and at least one sub-connection tube. The main connecting pipe is positioned in the tank body and is connected with the air supply pipe, and the main connecting pipe is also connected with the branch connecting pipes.
In some preferred forms, the ends of the sub-connecting pipes are closed, and the pipe bodies of the sub-connecting pipes are provided with air outlets. The number of the air outlets can be one or two or more, and the air outlets can be set according to actual needs. Similarly, the size, shape and position of the air outlet can be set according to actual needs.
In some preferred modes, the air outlets are uniformly arranged on the pipe bodies of the branch connecting pipes, and after the air is introduced into the main connecting pipe, the air can be discharged from the air outlets on each branch connecting pipe, so that oxygen can be more uniformly and more dispersed and can be more fully supplied for the thalli, the fermentation process is facilitated, and the influence on the fermentation process caused by the fact that oxygen cannot be obtained in certain corners of the tank body is avoided.
In some preferred forms, the total connection pipe is arranged vertically or/and horizontally with the sub-connection pipe; this results in a more dispersed and more uniform gas distribution within the tank. In other embodiments, the total connection pipe may be disposed at an acute angle to the sub-connection pipe.
Specifically, the air outlet component comprises a total connecting pipe and five branch connecting pipes, wherein four branch connecting pipes are uniformly arranged at the bottom of the tank body, the other branch connecting pipe is vertically arranged, and after being discharged from the branch connecting pipes, gas gradually moves upwards from the bottom of the tank body to continuously supplement oxygen for the thalli. If the branch connection pipe is positioned at the upper part of the tank body, oxygen is possibly not utilized, and is discharged out of the tank body. The total connecting pipes and the number of the branch connecting pipes can be set according to actual needs, and the set positions and the set heights of the branch connecting pipes can be set according to the actual needs.
In some preferred modes, a support is arranged at the bottom of the tank body, and can support the branch connecting pipe and enable the branch connecting pipe to be in a certain position so as to avoid sliding displacement.
In some preferred forms, a valve is provided on the gas supply tube for controlling whether gas is supplied to the interior of the tank.
In some preferred forms, the fermentation apparatus further comprises an exhaust system comprising an exhaust pipe, a check valve and a collection device, in some preferred forms, one end of the exhaust pipe is connected to the tank and the other end is connected to the collection device; the backflow prevention valve is arranged on the exhaust pipe and can prevent liquid in the collecting device from flowing back to the tank body.
In some preferred forms, the collection device contains a liquid, which may be clear water or clarified lime water, inside.
In some preferred forms, the air inlet end of the exhaust pipe is provided with a membrane which is selectively permeable to carbon dioxide gas, with less permeation of oxygen, water vapour, etc., so that the canister is able to preferentially vent carbon dioxide, avoiding carbon dioxide build-up.
In some preferred modes, the inner side wall of the tank body is also provided with a baffle plate, and the baffle plate is provided with an opening, so that tangential flow can be further weakened by the baffle plate, and axial flow and radial flow favorable for mixing are enhanced, and the mixing is uniform and sufficient.
In some preferred modes, the fermentation equipment further comprises a power device, the power device adopts a motor, a rotating shaft of the motor is connected with the stirring shaft, the stirring shaft can be driven to rotate, and the rotating speed and the rotating direction of the stirring shaft can be controlled by adjusting the rotating speed and the rotating direction of the motor.
In some preferred modes, a pressure gauge is connected to the tank body, so that the pressure value inside the tank body can be displayed in real time.
In some preferred forms, an automatic pressure relief valve is provided in the upper portion of the tank to stabilize the pressure inside the tank.
In some preferred modes, a sampling port is further arranged above the tank body and is used for sampling and monitoring.
In some preferred forms, the sides of the tank are provided with feed ports for the addition of materials such as bacteria, nutrients, substrates, and the like.
In some preferred modes, a discharge hole is arranged at the lower part of the side surface of the tank body and is used for collecting materials.
In some preferred forms, the bottom of the can is provided with legs for supporting the entire can.
In some preferred modes, the outer periphery of the tank body is provided with a sleeve, and cooling water pipes are spirally arranged in the sleeve, so that the whole tank body can be cooled.
In some preferred modes, the tank body is also provided with a viewing window which can be used for viewing the condition inside the tank body, and in some preferred modes, the viewing window is arranged on the side surface of the tank body.
The observation window department still is equipped with the shielding piece, shielding piece fixed connection is in the observation window top, specifically, is equipped with the axle above the observation window, and the upper end of shielding piece is equipped with the axle sleeve, and axle sleeve mutually support, and shielding piece can rotate around the axle. The connection mode of the shielding piece and the tank body is similar to the connection of a hinge type, so that the shielding piece can be conveniently opened or closed, and the reaction of light blocking can be met. When the observation is needed, the shielding piece can be lifted upwards, and after the observation, the shielding piece can be put down, so that the operation is convenient.
In some preferred modes, the main connecting pipe is connected with the transmission device, the transmission device is connected with the power device, the power device can drive the main connecting pipe to rotate through the transmission device, the sub-connecting pipe rotates along with the main connecting pipe, gas is discharged conveniently, and the gas is enabled to enter the mixed feed liquid more dispersedly and uniformly. Further, the transmission device comprises a driving wheel, a driven wheel and a transmission belt, wherein the driving wheel is connected with the power device, the driven wheel is connected with the main connecting pipe, and the transmission belt is respectively connected with the driving wheel and the driven wheel; the power plant may employ an electric motor to provide power. The air inlet end of the main connecting pipe is connected with the rotary joint, the air supply pipe is also connected with the rotary joint, and the main connecting pipe and the sub-connecting pipe can rotate relative to the air supply pipe, so that the air supply pipe can convey air to the main connecting pipe when the main connecting pipe and the sub-connecting pipe rotate.
In other embodiments, the air outlet component comprises only a main connecting pipe, the main connecting pipe is connected with the air supply pipe, and the main connecting pipe is in a spiral shape and is horizontally positioned at the bottom of the tank body. The total connecting pipe is uniformly provided with a plurality of openings, and the gas can be discharged from the openings into the tank body.
In other embodiments, the air outlet component only comprises a total connecting pipe, the total connecting pipe is connected with the air supply pipe, the total connecting pipe is spirally upwards from the bottom of the tank body, and the total connecting pipe is positioned at the periphery of the stirring shaft and the paddles and does not interfere with the stirring shaft and the paddles. In some preferred forms, a plurality of openings are evenly distributed over the total connection pipe, from which openings gas can be discharged into the tank.
In other embodiments, the air outlet component comprises a main connecting pipe and a sub-connecting pipe, wherein the main connecting pipe is in a spiral shape and is horizontally positioned at the bottom of the tank body; the sub-connecting pipes are arranged vertically to the main connecting pipe, are vertically positioned inside the tank body, and in some preferred modes, a plurality of openings are arranged at the periphery of the sub-connecting pipes, so that the gas is discharged. The branch connecting pipe does not interfere with the stirring shaft and the blade.
The can may be in the form of a conventional can or may be of other shapes, such as square, spherical, etc. The present application does not impose specific limitations thereon.
The stirring device, the air supply system, the air exhaust system or the fermentation apparatus of the present application may be used not only for biosynthesis but also for chemical synthesis or the like, and the present application is not particularly limited thereto.
The beneficial effects of the utility model are as follows:
(1) According to the utility model, the stirring structure comprises a stirring shaft, a first blade and a second blade, wherein the first blade is positioned at the upper part of the second blade, the first blade is a straight blade which is inclined downwards, the stirred liquid can be enabled to flip up and down, the upper-layer liquid is enabled to be quickly mixed with the lower-layer liquid, air or/and oxygen is enabled to be uniformly distributed in the liquid, tangential flow (tangential flow is unfavorable for mixing, tangential flow is fluid whirling, fluid is mainly discharged from the blades to the periphery, the quantity of fluid sucked to the blade area is small, and the fluid mixing effect in the vertical direction is poor) in the tank body can be reduced. The second paddle is spiral, and the second paddle is upwards along the (mixing) shaft spiral, and such paddle stirs more fully, is favorable to the intensive contact of each material to mix to can promote dissolved oxygen, be favorable to fermentation reaction's going on, spiral structure can also reduce the injury to the thallus.
The stirring structure provided by the utility model has the advantages of more sufficient stirring and better mixing effect, is beneficial to smoothly discharging carbon dioxide out of the tank body, and can be used for dispersing heat and avoiding accumulation of carbon dioxide, heat and the like. The stirring was sufficient and the sampling point data was representative.
(2) In the utility model, the air supply system comprises an air outlet component, an air supply pipe, a sterilizer and an air pump, wherein the air outlet component comprises a main connecting pipe and/or at least one sub-connecting pipe; the total connecting pipe and the branch connecting pipe are mutually perpendicular and arranged at the bottom of the tank body, the end parts of the branch connecting pipes are closed, the pipe bodies of the branch connecting pipes are uniformly provided with air outlets, after the air is introduced into the total connecting pipe, the air can be discharged from the air outlets on the branch connecting pipes, so that oxygen can be provided for the thalli more uniformly and more dispersedly, the fermentation process is facilitated, and the influence on the fermentation process due to the fact that oxygen cannot be obtained in certain corners of the tank body is avoided. After the gas is discharged from the branch connecting pipe, the gas gradually moves upwards from the bottom of the tank body to continuously supplement oxygen for the thalli; if the branch connection pipe is positioned at the upper part of the tank body, oxygen is possibly not utilized, and is discharged out of the tank body.
(3) In the utility model, the exhaust system comprises the exhaust pipe, the check valve and the collecting device, and the check valve is arranged on the exhaust pipe and can prevent liquid in the collecting device from flowing back to the tank body. The inlet end of the exhaust pipe is provided with a membrane, carbon dioxide gas can be selectively transmitted through the membrane, and oxygen, water vapor and the like are less in transmission, so that the tank body can be used for preferentially discharging carbon dioxide, and carbon dioxide accumulation is avoided.
(4) In the utility model, the main connecting pipe is connected with the transmission device, the transmission device is connected with the power device, the power device can drive the main connecting pipe to rotate through the transmission device, the branch connecting pipes rotate along with the main connecting pipe, the gas is favorably discharged, and the gas is more dispersed and more uniformly enters the mixed material liquid.
Drawings
FIG. 1 is a schematic view of a fermentation apparatus in example 1 (a part of the tank outer structure is hidden for the purpose of showing the tank inner structure).
Fig. 2 is a schematic diagram of the structure of the air supply system in embodiment 1.
Fig. 3 is a schematic view of the structure of the air supply system in embodiment 2.
Fig. 4 is a schematic structural view of the total connection pipe in embodiment 4.
Fig. 5 is a schematic structural view of the total connection pipe in embodiment 5.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more apparent, the present application is described and illustrated below with reference to the accompanying drawings and examples. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the present application. All other embodiments, which can be made by one of ordinary skill in the art without undue burden on the person of ordinary skill in the art based on the embodiments provided herein, are intended to be within the scope of the present application.
Reference in the specification to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment may be included in at least one embodiment of the application. The appearances of such phrases in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is to be expressly and implicitly understood by those of ordinary skill in the art that the embodiments described herein can be combined with other embodiments without conflict.
Unless defined otherwise, technical or scientific terms used herein should be given the ordinary meaning as understood by one of ordinary skill in the art to which this application belongs. Reference to "a," "an," "the," and similar terms herein do not denote a limitation of quantity, but rather denote the singular or plural. The terms "comprising," "including," "having," and any variations thereof, are intended to cover a non-exclusive inclusion; the terms "connected," "connected," and the like in this application are not limited to physical or mechanical connections, but may include electrical connections, whether direct or indirect. The term "plurality" as used herein means greater than or equal to two. "and/or" describes an association relationship of an association object, meaning that there may be three relationships, e.g., "a and/or B" may mean: a exists alone, A and B exist together, and B exists alone. The terms "first," "second," "third," and the like, as used herein, are merely distinguishing between similar objects and not representing a particular ordering of objects.
Example 1
As shown in FIG. 1, the high-density fermentation equipment comprises a tank body 1, a stirring structure and an air supply system, wherein the stirring structure and the air supply system are respectively connected with the tank body 1; the stirring structure is located inside the tank 11, the stirring structure includes a stirring shaft 2, a first blade 3 and a second blade 4, where the first blade 3 and the second blade 4 are connected with the stirring shaft 2 respectively, in this embodiment, as shown in fig. 1, the first blade 3 is located on the upper portion of the second blade 4, and the first blade 3 is a straight blade inclined downward, so that the stirred liquid can be turned up and down, and the upper layer of liquid is caused to be mixed with the lower layer of liquid, so that air or/and oxygen is uniformly distributed in the liquid, tangential flow (tangential flow is unfavorable for mixing, tangential flow is fluid whirling, fluid is mainly discharged from the blades to the periphery, the amount of fluid sucked into the blade area is very small, and the fluid mixing effect in the vertical direction is very poor) in the tank 1 can be reduced. In this embodiment, as shown in fig. 1, the number of the first paddles 3 is two, and the two paddles are disposed to intersect. In a specific embodiment, the number and positions of the first paddles may be set according to actual conditions.
In some preferred modes, as shown in fig. 1, the second blade 4 is spiral, the second blade spirals upwards along the stirring shaft 2, so that the stirring of the blades is more sufficient, the full contact and mixing of materials are facilitated, dissolved oxygen can be promoted, and the damage to thalli can be reduced due to the spiral structure.
The air supply system is configured to supply air or oxygen, increase the oxygen concentration in the mixed feed liquid and supply oxygen to the bacteria. In some preferred forms, the air supply system includes an air outlet member, an air supply tube 6, a sterilizer 7, and an air pump 40, as shown in FIG. 1, the air outlet member being connected to the air supply tube 6, the air supply tube 6 being connected to the sterilizer 7, the sterilizer 7 also being connected to the air pump 40. In some preferred forms, the air outlet member is provided with an air outlet 8. As shown in fig. 1-2, the gas outlet means comprises a main connection pipe 9 and at least one sub-connection pipe 10. The main connecting pipe 9 is positioned inside the tank body 1, the main connecting pipe 9 is connected with the air supply pipe 6, the main connecting pipe 9 is also connected with the sub-connecting pipe 10, in some preferred modes, the end parts of the sub-connecting pipes 10 are closed, and the pipe bodies of the sub-connecting pipes 10 are provided with air outlets 8. The number of the air outlets 8 can be one or two or more, and can be set according to actual needs. Similarly, the size, shape and position of the air outlet can be set according to actual needs. In some preferred modes, the air outlets 8 are uniformly arranged on the pipe bodies of the branch connecting pipes 10, and after the air is introduced into the main connecting pipes, the air can be discharged from the air outlets 8 on each branch connecting pipe 10, so that oxygen can be more uniformly and more dispersed and more fully supplied for the thalli, the fermentation process is facilitated, and the influence on the fermentation process due to the fact that oxygen cannot be obtained in certain corners of the tank body is avoided.
In some preferred forms, the total connection pipe is arranged vertically or/and horizontally with the sub-connection pipe; this results in a more dispersed and more uniform gas distribution within the tank. In other embodiments, the total connection pipe may be disposed at an acute angle to the sub-connection pipe.
In this embodiment, as shown in fig. 1-2, the air outlet component includes a main connecting pipe 9 and five sub-connecting pipes 10, wherein four sub-connecting pipes are uniformly arranged at the bottom of the tank body, and the other sub-connecting pipe is vertically arranged, and after the air is discharged from the sub-connecting pipes, the air gradually moves upwards from the bottom of the tank body to continuously supplement oxygen for the thalli. The branch connecting pipe is arranged at the bottom of the tank body, and the gas can be fully utilized in the rising process; if the branch connection pipe is positioned at the upper part of the tank body, oxygen is possibly not utilized, and is discharged out of the tank body.
In other embodiments, the total connection pipe 9 may be plural, and the sub connection pipe 10 may be one, two, three, four, etc. other numbers, and the plural sub connection pipes 10 are uniformly connected to the total connection pipe 9. The total connecting pipes and the number of the branch connecting pipes can be set according to actual needs, and the set positions and the set heights of the branch connecting pipes can be set according to the actual needs.
In some preferred ways, as shown in fig. 1, a support 51 is provided at the bottom of the tank, and the support 51 can support the sub-connection pipe 10 and can keep the sub-connection pipe 10 at a certain position to avoid sliding displacement.
In some preferred forms, as shown in figure 1, the gas supply pipe 6 is provided with a valve 11 for controlling whether gas is supplied to the interior of the tank 1.
In some preferred ways, the fermentation apparatus further comprises an exhaust system comprising an exhaust pipe 12, a non-return valve 13 and a collecting device 14, in some preferred ways, as shown in fig. 1, the exhaust pipe 12 is connected at one end to the tank and at the other end to the collecting device; the backflow prevention valve 13 is provided in the exhaust pipe 12, and can prevent the liquid in the collection device from flowing back to the tank. In some preferred forms, the collection device 14 contains a liquid, which may be clear water or clarified lime water, inside. In some preferred forms, the inlet end of the exhaust pipe 12 is provided with a membrane 61, the membrane 61 being selectively permeable to carbon dioxide gas, less permeable to oxygen, water vapour, etc., so that the tank can preferentially vent carbon dioxide, avoiding carbon dioxide build-up.
In some preferred modes, as shown in fig. 1, the inner side wall of the tank body 1 is further provided with a baffle 15, and the baffle 15 is provided with openings, so that tangential flow can be further weakened by the baffle 15, and axial flow and radial flow favorable for mixing are enhanced, and the mixing is uniform and sufficient.
In some preferred manners, the fermentation apparatus further includes a power device, in this embodiment, as shown in fig. 1, the power device adopts a motor 81, a rotation shaft of the motor 81 is connected with the stirring shaft 2, and can drive the stirring shaft 2 to rotate, and by adjusting a rotation speed and a rotation direction of the motor 81, the rotation speed and the rotation direction of the stirring shaft 2 can be controlled.
In some preferred ways, as shown in fig. 1, a pressure gauge 30 is connected to the tank 1, so as to display the pressure value inside the tank in real time.
In some preferred ways, as shown in fig. 1, an automatic pressure relief valve 19 is provided in the upper part of the tank 1 for stabilizing the pressure inside the tank 1.
In some preferred ways, as shown in fig. 1, a sampling port 100 is also provided above the tank 1 for sampling monitoring.
In some preferred forms, as shown in fig. 1, the side or upper portion of the tank 1 is provided with a feed port 111 for feeding materials such as bacteria, nutrients, substrates, etc.
In some preferred forms, as shown in fig. 1, a discharge port 112 is provided in the lower portion of the side of the tank 1 for collecting material.
In some preferred forms, as shown in fig. 1, the bottom of the can 1 is provided with legs 113 for supporting the entire can 1.
In some preferred modes, the periphery of the tank body 1 is provided with a sleeve, and a cooling water pipe is spirally arranged in the sleeve, so that the whole tank body 1 can be cooled.
In some preferred ways, as shown in fig. 1, a viewing window 115 is further provided on the tank body, which can be used for viewing the internal condition of the tank body, and in some preferred ways, the viewing window 115 is provided on the side surface of the tank body 1.
The observation window 115 is further provided with a shielding member fixedly connected above the observation window 115, specifically, a shaft is arranged above the observation window 115, the upper end of the shielding member is provided with a shaft sleeve, the shaft and the shaft sleeve are mutually matched, and the shielding member can rotate around the shaft. The connection mode of the shielding piece and the tank body 1 is similar to the connection of a hinge type, so that the shielding piece can be conveniently opened or closed, and the reaction of light blocking can be satisfied. When the observation is needed, the shielding piece can be lifted upwards, and after the observation, the shielding piece can be put down, so that the operation is convenient.
The tank 1 may be in the form of a conventional tank or may be of other shape, such as square, spherical, etc. The present application does not impose specific limitations thereon.
The stirring device, the air supply system, the air exhaust system or the fermentation apparatus of the present application may be used not only for biosynthesis but also for chemical synthesis or the like, and the present application is not particularly limited thereto.
Example 2, refer to fig. 3.
In this embodiment, the main connecting pipe 9 is connected with a transmission device, the transmission device is connected with a power device, the power device can drive the main connecting pipe 9 to rotate through the transmission device, the sub-connecting pipes 10 rotate along with the main connecting pipe, which is favorable for discharging gas, and the gas can be more dispersed and more uniformly enter the mixed material liquid. Specifically, the transmission device comprises a driving wheel, a driven wheel 20 and a transmission belt, wherein the driving wheel is connected with the power device, the driven wheel 20 is connected with the main connecting pipe 9, and the transmission belt is respectively connected with the driving wheel and the driven wheel 20; the power plant may employ an electric motor to provide power.
In some preferred embodiments, the air inlet end of the main connecting pipe 9 is connected to the rotary joint 21, the air supply pipe 6 is also connected to the rotary joint 21, and the main connecting pipe 9 and the sub-connecting pipe 10 can rotate relative to the air supply pipe 6, so that the air supply pipe 6 can supply air to the main connecting pipe 9 when the main connecting pipe 9 and the sub-connecting pipe 10 rotate.
The implementation in this example may be the same as or similar to example 1.
Example 3
In this embodiment, the stirring shaft 2 has an inner cavity, through holes are formed at different height positions of the stirring shaft 2, and the inner cavity can be communicated with the inside of the tank 1 through the through holes.
The implementation in this example may be the same as or similar to example 1.
Example 4, refer to fig. 4.
In this embodiment, the air outlet part only includes a main connection pipe 9, the main connection pipe 9 is connected with the air supply pipe 6, and the main connection pipe 9 is spirally and horizontally positioned at the bottom of the tank body. In some preferred ways, a plurality of openings are uniformly distributed over the total connection pipe 9, from which it is possible to discharge gas (which may be air, oxygen, etc.) into the tank interior.
The implementation in this example may be the same as or similar to example 1.
Example 5, refer to fig. 5.
In this embodiment, the air outlet component only includes total connecting pipe 9, and total connecting pipe 9 is connected with air supply pipe 6, and total connecting pipe 9 is upwards by jar body bottom spiral, and total connecting pipe 9 is located the (mixing) shaft and the paddle periphery, does not interfere with (mixing) shaft, paddle. Correspondingly, the tank body is internally provided with a supporting piece 52, the supporting piece 52 is fixedly connected with the tank body, and the supporting piece 52 can support the main connecting pipe 9 to be in a fixed position so as to avoid displacement. In some preferred ways, a plurality of openings are uniformly distributed over the total connection pipe 9, from which it is possible to discharge gas (which may be air, oxygen, etc.) into the tank interior.
The implementation in this example may be the same as or similar to example 1.
Example 6
In this embodiment, the air outlet member includes a main connection pipe 9 and a sub-connection pipe, the main connection pipe 9 is connected to the air supply pipe, and the sub-connection pipe is connected to the main connection pipe 9. In some embodiments, the total connection pipe 9 is in a spiral shape and is horizontally positioned at the bottom of the tank body; the sub-connection pipes are arranged perpendicular to the main connection pipe 9, are vertically located inside the tank body, and in some embodiments, are provided with a plurality of openings around the sub-connection pipes, which facilitate gas discharge. The branch connecting pipe does not interfere with the stirring shaft and the blade.
The implementation in this example may be the same as or similar to example 1.
The utility model and its embodiments have been described above by way of illustration and not limitation, and the utility model is illustrated in the accompanying drawings and described in the drawings in which the actual structure is not limited thereto. Therefore, if one of ordinary skill in the art is informed by this disclosure, the structural mode and the embodiments similar to the technical scheme are not creatively designed without departing from the gist of the present utility model.

Claims (10)

1. The high-density fermentation equipment is characterized by comprising a tank body, a stirring structure and an air supply system, wherein the stirring structure and the air supply system are respectively connected with the tank body;
the stirring structure is positioned in the tank body and comprises a stirring shaft, a first blade and a second blade, the first blade and the second blade are respectively connected with the stirring shaft, the first blade is positioned at the upper part of the second blade, and the first blade is a straight blade which is inclined downwards, so that the stirred feed liquid is enabled to tumble up and down;
the second paddle is spiral, and the second paddle is upwards spiral along the stirring shaft.
2. The high-density fermentation apparatus according to claim 1, wherein the air supply system comprises an air outlet member, an air supply pipe, a sterilizer, and an air pump, the air outlet member is connected to the air supply pipe, the air supply pipe is connected to the sterilizer, and the sterilizer is connected to the air pump.
3. The high-density fermentation apparatus according to claim 2, wherein the gas outlet member comprises a total connection pipe and at least one sub-connection pipe, the total connection pipe being located inside the tank, the total connection pipe being connected to the gas supply pipe, the total connection pipe being connected to the sub-connection pipe;
or the air outlet part only comprises a main connecting pipe, the main connecting pipe is connected with the air supply pipe, the main connecting pipe is spirally upwards from the bottom of the tank body, and at least one opening is uniformly distributed on the main connecting pipe;
or the air outlet component comprises a main connecting pipe and a branch connecting pipe, the main connecting pipe is in a spiral shape and is horizontally positioned at the bottom of the tank body, the branch connecting pipe is vertically arranged with the main connecting pipe, the branch connecting pipe is vertically positioned in the tank body, and at least one opening is arranged at the periphery of the branch connecting pipe.
4. A high-density fermentation apparatus according to claim 3, wherein the ends of the branch connecting pipes are closed, the pipe bodies of the branch connecting pipes are provided with air outlets, and the number of the air outlets is one or two or more.
5. A high-density fermentation apparatus according to claim 3 or 4, wherein the total connection pipe is arranged vertically and/or horizontally to the branch connection pipe.
6. The high-density fermentation apparatus according to claim 5, wherein the gas outlet member comprises a main connection pipe and at least one sub-connection pipe, wherein one sub-connection pipe is vertically arranged, and the other sub-connection pipe is uniformly arranged at the bottom of the tank.
7. A high-density fermentation apparatus according to claim 3, wherein the main connecting pipe is connected to a transmission means, the transmission means is connected to a power means, the power means is capable of driving the main connecting pipe to rotate by the transmission means, and the sub-connecting pipe rotates accordingly.
8. The high-density fermentation apparatus according to claim 1, further comprising an exhaust system comprising an exhaust pipe, a check valve and a collecting device, wherein one end of the exhaust pipe is connected with the tank, and the other end is connected with the collecting device; the check flow valve is arranged on the exhaust pipe to prevent liquid in the collecting device from flowing back to the tank body, and a membrane is arranged at the air inlet end of the exhaust pipe and can selectively permeate carbon dioxide gas.
9. The high-density fermentation equipment according to claim 1, further comprising a power device, wherein the power device adopts a motor, and a rotating shaft of the motor is connected with the stirring shaft to drive the stirring shaft to rotate.
10. The high-density fermentation equipment according to claim 1, wherein the tank body is further provided with an observation window for observing the internal condition of the tank body; a shielding piece is further arranged at the observation window and fixedly connected above the observation window; the upper part of the observation window is provided with a shaft, the upper end of the shielding piece is provided with a shaft sleeve, the shaft is matched with the shaft sleeve, and the shielding piece can rotate around the shaft.
CN202223144571.1U 2022-11-25 2022-11-25 High-density fermentation equipment Active CN219217971U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202223144571.1U CN219217971U (en) 2022-11-25 2022-11-25 High-density fermentation equipment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202223144571.1U CN219217971U (en) 2022-11-25 2022-11-25 High-density fermentation equipment

Publications (1)

Publication Number Publication Date
CN219217971U true CN219217971U (en) 2023-06-20

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202223144571.1U Active CN219217971U (en) 2022-11-25 2022-11-25 High-density fermentation equipment

Country Status (1)

Country Link
CN (1) CN219217971U (en)

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