CN219179201U - Linear light source device and detection system for IVD imaging detection - Google Patents
Linear light source device and detection system for IVD imaging detection Download PDFInfo
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- CN219179201U CN219179201U CN202223571391.1U CN202223571391U CN219179201U CN 219179201 U CN219179201 U CN 219179201U CN 202223571391 U CN202223571391 U CN 202223571391U CN 219179201 U CN219179201 U CN 219179201U
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Abstract
The utility model discloses a line light source device and a line light source detection system for IVD imaging detection, wherein the line light source device comprises a detection objective table and a line light source, the line light source is positioned above the detection objective table, the light ray emergent end of the line light source faces the detection objective table, and the distances from each point of a light spot bright area formed on the detection objective table by irradiation of the line light source to the line light source are equal. The utility model uses the linear light source as the light source for irradiating the detection object stage, can make the illumination of the detected sample imaging observation area uniform, reduces the system error caused by the uneven irradiation of the point light source, and makes the observation area obviously different from the surrounding area, and reduces the interference, thereby making the IVD detection result based on the image analysis more accurate.
Description
Technical Field
The utility model belongs to the technical field of biological imaging detection, and particularly relates to a linear light source device and a detection system for IVD imaging detection.
Background
In Vitro Diagnostic (IVD) technology and industry have been rapidly developed in recent years and are advancing in a direction of convenience, ease of use and accuracy, so that a great deal of biological, medical, chemical, optical and electrical technologies are fused to convert detection reactions for target substances into signals that are easier for human recognition. For example, a detection technique based on fluorescence imaging is a means for indirectly qualitatively or quantitatively detecting the amount or concentration of a target substance by detecting the fluorescence intensity of a fluorescent substance or a fluorescent group. Since fluorescent materials need to emit fluorescence under specific excitation light irradiation, the illuminance of the excitation light affects the detection result, and especially the uniformity of illumination at different positions of the detected area of the sample is very important, such as the target area of the detection card, where a comparison judgment or quantitative analysis of the detection result is required. The detection device commonly used at present adopts a plurality of point light sources to be annularly arranged, so that the excitation light irradiation intensity of each point of a target area is as close as possible, but the expected intensity is difficult to reach in actual use. In the automatic detection and analysis process, the detection card based on the color reaction also needs to take a picture under illumination, quantitative judgment is carried out through image analysis, and the problem that the analysis result is influenced due to uneven illumination exists. Improving the consistency of illumination intensity of a target area from the perspective of equipment is helpful for further improving the accuracy of optical imaging analysis results.
Disclosure of Invention
Accordingly, one of the objectives of the present utility model is to provide a line light source device for IVD imaging detection, which irradiates the detection stage with a line light source to make the illumination of the imaging observation area of the detected sample uniform and the detection result more accurate.
In order to achieve the above purpose, the technical scheme of the utility model is as follows:
the line light source device for IVD imaging detection is characterized by comprising a detection object stage and a line light source, wherein the line light source is positioned above the detection object stage, the light ray emergent end of the line light source faces the detection object stage, and the line light source irradiates points of a light spot bright area formed on the detection object stage and the distance from the points to the line light source are equal.
Preferably, the line light source is supported on a distance adjusting mechanism for adjusting a distance between a light emitting end of the line light source and the detection stage;
the line light source is a laser light source.
Preferably, the distance adjusting mechanism is a linear sliding mechanism or a linear telescopic mechanism, an adjusting direction of a movable portion of the distance adjusting mechanism is parallel to a light emitting direction of the linear light source, the linear light source is arranged on the movable portion of the distance adjusting mechanism, and an emitting light of the linear light source is obliquely and downwardly irradiated onto the detection object stage.
Preferably, the linear sliding mechanism is a sliding rail and sliding block assembly and comprises a sliding guide rail and a sliding block which are matched with each other, wherein the sliding guide rail is fixedly arranged through a bracket and is parallel to the light emergent direction of the linear light source, the linear light source is fixedly arranged on the sliding block, and a locking mechanism is arranged between the sliding block and the sliding guide rail.
Preferably, the linear telescopic mechanism is a sliding rail assembly and comprises a first sliding rail and a second sliding rail which are in sliding fit with each other, the first sliding rail is fixedly arranged through a bracket, the second sliding rail is arranged on the first sliding rail in a sliding manner, a locking mechanism is arranged between the first sliding rail and the second sliding rail, and the front end of the second sliding rail is provided with the linear light source.
Preferably, the distance adjusting mechanism comprises a lifting mechanism, the lifting mechanism is vertically arranged, the upper end of the lifting mechanism is provided with the linear light source through a rotation adjusting mechanism, and the rotation adjusting mechanism is used for adjusting the light emergent angle of the linear light source.
Preferably, the rotation adjusting mechanism comprises a vertically arranged mounting plate, and an arc-shaped hole is formed in the mounting plate;
a rotating shaft is arranged on the mounting plate, and the axial lead of the rotating shaft passes through the circle center corresponding to the arc-shaped hole;
the linear light source is rotatably installed on the rotating shaft, the shell of the linear light source is connected with the arc-shaped hole through a positioning bolt, the positioning bolt penetrates through the arc-shaped hole, the positioning bolt is loosened to enable the positioning bolt to slide along the arc-shaped hole, and the positioning bolt is fastened to enable the light emergent angle of the linear light source to be fixed.
Preferably, the detection stage is provided with at least one sample positioning structure.
It is a second object of the present utility model to provide a detection system.
The technical scheme is as follows:
a detection system comprising a line light source device for IVD imaging detection as claimed in any one of the above, and an imaging assembly comprising a lens and a photosensitive module, wherein the lens is located right above the detection stage, the optical axis of the lens is perpendicular to the detection stage, and the light emitted from the detection stage reaches the photosensitive module through the lens;
the linear light source is arranged outside the optical axis of the lens.
Preferably, the detection system further comprises a filter element, and the filter element is located on an optical path between the detection object stage and the lens or an optical path between the lens and the photosensitive module.
The beneficial effects are that: the utility model uses the linear light source as the light source for irradiating the detection object stage, can make the illumination of the detected sample imaging observation area uniform, reduces the system error caused by the uneven irradiation of the point light source, and makes the observation area obviously different from the surrounding area, and reduces the interference, thereby making the IVD detection result based on the image analysis more accurate.
Drawings
FIG. 1 is a schematic diagram of a first embodiment of a detection system according to the present utility model;
FIG. 2 is a schematic diagram of a second embodiment of the detection system of the present utility model;
FIG. 3 is a schematic diagram of a third embodiment of the detection system of the present utility model;
FIG. 4 is a schematic view of a light beam from a linear light source of the present utility model striking a detection stage;
FIG. 5 is a schematic diagram of a detection system with a filter element.
Detailed Description
The utility model is further described below with reference to examples and figures.
Example 1
The utility model provides a line light source device for IVD formation of image detects, includes detects objective table 1 and line light source 2, and this line light source 2 is located detect objective table 1 top, the light exit end of this line light source 2 is towards detect objective table 1, line light source 2 shines the facula bright region each point that forms on detect objective table 1 is equal to the distance of line light source 2, and the outgoing beam central line of line light source 2 is located the plane that is parallel with detects objective table 1 surface. Since the light spot area formed by the irradiation of the linear light source 2 to the detection stage 1 is a light spot line segment, the irradiation angle makes the illumination intensity of each point on the light spot line segment substantially uniform.
The line light source 2 may be a laser light source, and is composed of a laser point light source and a line laser element, and the line laser element may be a line laser generator, that is, a powell lens. The line light source 2 may be an LED lamp.
The line light source 2 is supported on a distance adjusting mechanism for adjusting the distance between the light emitting end of the line light source 2 and the detection stage 1.
The distance adjusting mechanism may be a linear sliding mechanism 3 or a linear telescopic mechanism 4, an adjusting direction of a movable portion of the distance adjusting mechanism is parallel to a light emitting direction of the line light source 2, the line light source 2 is arranged on the movable portion of the distance adjusting mechanism, and emitted light of the line light source 2 is obliquely and downwardly irradiated onto the detection object stage 1.
Fig. 1 illustrates that the linear sliding mechanism 3 is a sliding rail and sliding block 32 assembly, and includes a sliding guide rail 31 and a sliding block 32 that are matched with each other, wherein the sliding guide rail 31 is fixedly arranged through a bracket 5 and is parallel to the light emitting direction of the linear light source 2, the linear light source 2 is fixedly arranged on the sliding block 32, and a locking mechanism, such as a locking nut, is arranged between the sliding block 32 and the sliding guide rail 31.
Fig. 2 illustrates that the linear telescopic mechanism 4 is a sliding rail assembly, and comprises a first sliding rail 41 and a second sliding rail 42 which are in sliding fit with each other, the first sliding rail 41 is fixedly arranged through a bracket 5, the second sliding rail 42 is slidably arranged on the first sliding rail 41, a locking mechanism is arranged between the first sliding rail 41 and the second sliding rail 42, and the front end of the second sliding rail 42 is provided with the linear light source 2.
In another embodiment, as shown in fig. 3, the distance adjusting mechanism includes a lifting mechanism 6, the lifting mechanism 6 is vertically disposed, the upper end of the lifting mechanism 6 is provided with the linear light source 2 through a rotation adjusting mechanism 7, and the rotation adjusting mechanism 7 is used for adjusting the light emergent angle of the linear light source 2. This adjustment can change the angle of the light beam irradiated from the line light source 2 to the detection stage 1. The lifting mechanism 6 may use a common telescopic rod.
The rotation adjusting mechanism 7 comprises a vertically arranged mounting plate 71, and an arc-shaped hole 72 is formed in the mounting plate 71. A rotating shaft 73 is disposed on the mounting plate 71, and a shaft axis of the rotating shaft 73 passes through a center of the arc hole 72. The line light source 2 is rotatably mounted on the rotating shaft 73, the housing of the line light source 2 is further connected with the arc-shaped hole 72 through a positioning bolt 74, the positioning bolt 74 is arranged in the arc-shaped hole 72 in a penetrating mode, the positioning bolt 74 is loosened to enable the positioning bolt 74 to slide along the arc-shaped hole 72, and the positioning bolt 74 is fastened to enable the light emergent angle of the line light source 2 to be fixed.
Furthermore, as shown in fig. 4, at least one sample positioning structure 1a is provided on the detection stage 1. For example, in order to facilitate placement of the test card, a groove adapted to the test card is provided on the test stage 1. Further, the two sides of one end of the groove are respectively provided with a yielding gap, so that an operator can conveniently take and place the detection card.
Example two
As shown in fig. 1 to 3, a detection system includes a line light source device for IVD imaging detection as described above, and further includes an imaging assembly 8, the imaging assembly 8 includes a lens 8a and a photosensitive module 8b, the lens 8a is located directly above the detection stage 1, an optical axis of the lens 8a is perpendicular to the detection stage 1, and light emitted from the detection stage 1 reaches the photosensitive module 8b through the lens 8 a. The photosensitive module 8b transmits the electric signal to the developing device. The line light source 2 is arranged outside the optical axis of the lens 8 a. The line light source 2 serves as an illumination light source for imaging.
Another detection system detects based on fluorescence imaging, so the imaging assembly 8 also includes a filter element 8c. As shown in fig. 5, the filter element 8c is located on the optical path between the detection stage 1 and the lens 8a, i.e., the position (1) in fig. 5; or the filter element 8c is located on the optical path between the lens 8a and the photosensitive module 8b, i.e. the position (2) in fig. 5. The filter element 8c may be a narrow band filter or a filter film plated on the lens 8 a. When the device is used for fluorescence imaging, the consistency of the relative intensity of fluorescence emitted light at each part of an observation area and the concentration of the measured fluorescent substance is higher.
Typical application scenarios of the device are immunofluorescence imaging, upward forwarding light imaging and detection of microfluidic chip imaging.
Finally, it should be noted that the above description is only a preferred embodiment of the present utility model, and that many similar changes can be made by those skilled in the art without departing from the spirit and scope of the utility model as defined in the appended claims.
Claims (10)
1. A line source apparatus for IVD imaging detection, characterized in that: including detecting objective table (1) and line light source (2), this line light source (2) are located detect objective table (1) top, the light exit end of this line light source (2) is towards detect objective table (1), line light source (2) are shone spot light area each point that forms on detect objective table (1) reaches the distance of line light source (2) equals.
2. A line light source device for IVD imaging detection as claimed in claim 1, wherein: the linear light source (2) is supported on a distance adjusting mechanism, and the distance adjusting mechanism is used for adjusting the distance between the light ray emergent end of the linear light source (2) and the detection objective table (1);
the line light source (2) is a laser light source.
3. A line light source device for IVD imaging detection according to claim 2, wherein: the distance adjusting mechanism is a linear sliding mechanism (3) or a linear telescopic mechanism (4), the adjusting direction of the movable part of the distance adjusting mechanism is parallel to the light emergent direction of the linear light source (2), the linear light source (2) is arranged on the movable part of the distance adjusting mechanism, and emergent light of the linear light source (2) obliquely irradiates downwards onto the detection objective table (1).
4. A line light source device for IVD imaging detection as in claim 3, wherein: the linear sliding mechanism (3) is a sliding rail and sliding block (32) assembly and comprises a sliding guide rail (31) and a sliding block (32) which are matched with each other, wherein the sliding guide rail (31) is fixedly arranged through a bracket (5) and is parallel to the light emergent direction of the linear light source (2), the linear light source (2) is fixedly arranged on the sliding block (32), and a locking mechanism is arranged between the sliding block (32) and the sliding guide rail (31).
5. A line light source device for IVD imaging detection as in claim 3, wherein: the linear telescopic mechanism (4) is a sliding rail assembly and comprises a first sliding rail (41) and a second sliding rail (42) which are in sliding fit with each other, the first sliding rail (41) is fixedly arranged through a support (5), the second sliding rail (42) is arranged on the first sliding rail (41) in a sliding mode, a locking mechanism is arranged between the first sliding rail and the second sliding rail, and the front end of the second sliding rail (42) is provided with the linear light source (2).
6. A line light source device for IVD imaging detection according to claim 2, wherein: the distance adjusting mechanism comprises a lifting mechanism (6), the lifting mechanism (6) is vertically arranged, the upper end of the lifting mechanism (6) is provided with the linear light source (2) through a rotation adjusting mechanism (7), and the rotation adjusting mechanism (7) is used for adjusting the light emergent angle of the linear light source (2).
7. The line light source device for IVD imaging detection of claim 6, wherein: the rotation adjusting mechanism (7) comprises a vertically arranged mounting plate (71), and an arc-shaped hole (72) is formed in the mounting plate (71);
a rotating shaft (73) is arranged on the mounting plate (71), and the axial lead of the rotating shaft (73) passes through the circle center corresponding to the arc-shaped hole (72);
the linear light source (2) is rotatably mounted on the rotating shaft (73), the shell of the linear light source (2) is connected with the arc-shaped hole (72) through a positioning bolt (74), the positioning bolt (74) penetrates through the arc-shaped hole (72), the positioning bolt (74) is loosened to enable the positioning bolt to slide along the arc-shaped hole (72), and the positioning bolt (74) is fastened to enable the light emergent angle of the linear light source (2) to be fixed.
8. A line source apparatus for IVD imaging detection according to any one of claims 1 to 7, wherein: at least one sample positioning structure (1 a) is arranged on the detection object stage (1).
9. A detection system comprising a line source apparatus for IVD imaging detection as claimed in any one of claims 1 to 7, wherein: the imaging device comprises a detection object stage (1), and is characterized by further comprising an imaging assembly (8), wherein the imaging assembly (8) comprises a lens (8 a) and a photosensitive module (8 b), the lens (8 a) is positioned right above the detection object stage (1), the optical axis of the lens (8 a) is perpendicular to the detection object stage (1), and light rays emitted from the detection object stage (1) reach the photosensitive module (8 b) through the lens (8 a);
the linear light source (2) is arranged outside the optical axis of the lens (8 a).
10. A detection system according to claim 9, wherein: the device also comprises a light filtering element (8 c), wherein the light filtering element (8 c) is positioned on an optical path between the detection object stage (1) and the lens (8 a) or on an optical path between the lens (8 a) and the photosensitive module (8 b).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202223571391.1U CN219179201U (en) | 2022-12-15 | 2022-12-15 | Linear light source device and detection system for IVD imaging detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202223571391.1U CN219179201U (en) | 2022-12-15 | 2022-12-15 | Linear light source device and detection system for IVD imaging detection |
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| Publication Number | Publication Date |
|---|---|
| CN219179201U true CN219179201U (en) | 2023-06-13 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202223571391.1U Active CN219179201U (en) | 2022-12-15 | 2022-12-15 | Linear light source device and detection system for IVD imaging detection |
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| Country | Link |
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| CN (1) | CN219179201U (en) |
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- 2022-12-15 CN CN202223571391.1U patent/CN219179201U/en active Active
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