CN219178932U

CN219178932U - 96-hole plate sampling mechanism based on CCD

Info

Publication number: CN219178932U
Application number: CN202223213627.4U
Authority: CN
Inventors: 卜海之; 文家杰; 西治国
Original assignee: Suzhou Shengsu New Drug Development Co ltd
Current assignee: Suzhou Shengsu New Drug Development Co ltd
Priority date: 2022-12-01
Filing date: 2022-12-01
Publication date: 2023-06-13
Anticipated expiration: 2032-12-01

Abstract

The utility model discloses a 96-hole plate sampling mechanism based on CCD, which comprises a bottom plate, a sampling unit and a fixed plate unit; the middle part of the right side of the upper end of the bottom plate is provided with a lifting module; the sampling unit comprises a translation module, a sliding seat, a first disk, a rod seat, a groove rod, an electric push rod, a second disk and a pull rod, wherein the right end of the translation module is slidably connected with the lifting module, the sliding seat is connected with the translation module in a left-right sliding manner, the first disk is installed at the lower end of the sliding seat, and the three rod seats are installed at the circumference of the lower end of the first disk at equal intervals. According to the utility model, through the movements of the three chucks, under the accurate positioning of the CCD camera, the sample chuck at the designated position on the 96-well plate can be taken out without touching surrounding samples, the sampling effect is better, the 96-well plate can be fixed by inserting the 96-well plate into the plate seat and utilizing the elasticity of the spring, the position positioning is more accurate, and the efficiency is higher during sampling.

Description

96-hole plate sampling mechanism based on CCD

Technical Field

The utility model relates to the technical field of pharmacokinetics, in particular to a 96-hole plate sampling mechanism based on CCD.

Background

The 96-well plate, namely the 96-well cell culture plate and dish series products, are manufactured by using imported optically transparent pure polystyrene. The method is characterized in that the method is prepared by adopting a special process, so that cells reach an optimal adsorption state, and all products are sterilized by gamma rays.

In the prior art, when samples in a 96-well plate are extracted, an operator is mostly required to hold the 96-well plate tightly by one hand, the samples at the appointed positions in the 96-well plate are pinched and taken out by the other hand, the samples around the samples are easily touched during the taking out, the samples are polluted, and the sampling effect is poor; when the 96-hole plate is held for sampling, certain force is required to be applied all the time, and the position of the 96-hole plate is offset due to easy relaxation during sampling, so that the sampling efficiency is reduced.

Disclosure of Invention

The utility model aims to overcome the existing defects, and provides the 96-pore plate sampling mechanism based on the CCD, through the movements of the three chucks, under the accurate positioning of the CCD camera, the sample clamp at the designated position on the 96-pore plate can be taken out without touching surrounding samples, the sampling effect is better, the 96-pore plate can be fixed by inserting the 96-pore plate into the plate seat through the elasticity of the spring, the position positioning is more accurate, the efficiency is higher during sampling, and the problems in the background technology can be effectively solved.

In order to achieve the above purpose, the present utility model provides the following technical solutions: a96-hole plate sampling mechanism based on CCD comprises a bottom plate, a sampling unit and a fixed plate unit;

the middle part of the right side of the upper end of the bottom plate is provided with a lifting module;

the sampling unit comprises a translation module with one end connected to the lifting module in a sliding way, a sliding seat connected to the translation module in a left-right sliding way, a first disk arranged at the lower end of the sliding seat, three rod seats with circumferences being equidistantly arranged at the lower end of the disk, a groove rod respectively connected to the lower end of the rod seat in a movable way, and a clamping head arranged at the lower end of the groove rod; the sampling unit further comprises an electric push rod arranged at the upper end of the first disc, a second disc arranged at the telescopic end of the electric push rod and three pull rods with the circumferences being equidistantly and movably connected to the lower end surfaces of the second disc, and the other ends of the three pull rods are respectively and movably connected to the groove rods;

the fixed plate unit is arranged at the upper end of the bottom plate.

Further, the sampling unit further comprises an annular light source and a CCD camera, wherein the annular light source is arranged at the lower end of the second disc, and the CCD camera is arranged in the middle of the lower end of the second disc. When the chucks under the three groove rods move to the periphery of the sample at the designated position on the 96-well plate, the CCD camera works, the holes around the sample can be shot, the moving position is detected, the sampling accuracy is ensured, the annular light source is electrified and luminous, light compensation can be carried out, and the shooting effect is improved.

Further, the fixed plate unit comprises groove strips, a plate seat, a corner plate and a front-back moving module, the groove strips in the front-back direction are arranged at the upper end of the bottom plate, the left side and the right side of the lower end of the plate seat are respectively and slidably connected in the two groove strips, the corner plate is arranged at the middle part of the lower end of the plate seat, the front-back moving module is arranged at the upper end of the bottom plate, and the moving end of the front-back moving module is connected with the lower end of the corner plate. The back and forth moving module can move back and forth to a proper position by carrying the plate seat through the angle plate.

Further, the fixed plate unit further comprises a spring box, a sliding plate and a sliding rod, the spring box is mounted on the front side of the middle of the lower end of the plate seat, the sliding plate is connected to the rear end of the interior of the spring box in a front-back sliding mode, the sliding rod is connected to the front end of the spring box in a front-back sliding mode, and the rear end of the sliding rod is connected to the middle of the front end of the sliding plate. After the 96-well plate with the sample is inserted into the plate seat, the clamping plate is rotated to the front side of the 96-well plate, the sliding plate is pushed to move backwards under the action of the spring, and the clamping plate is pulled to move backwards by the sliding rod, so that the 96-well plate with the sample is clamped.

Further, the fixed plate unit further comprises a spring and a clamping plate, the front end of the spring is connected to the front end of the interior of the spring box, the rear end of the spring is connected to the front end of the sliding plate, the front end of the sliding rod is rotationally connected with the clamping plate, and the front end of the clamping plate is provided with a T-shaped handle. The spring can provide power for the fixed 96-well plate, and the movable clamping plate can be achieved by pulling and rotating the T-shaped handle.

Further, the device further comprises cushion columns and conical seats, the cushion columns are arranged at four corners of the lower end of the bottom plate, and the conical seats are connected with the lower ends of the four cushion columns in a threaded mode. The conical seat is rotated to adjust the threaded connection length of the upper stud and the pad column.

Compared with the prior art, the utility model has the beneficial effects that:

1. the sampling unit is arranged, the translation module can move left and right with the sliding seat, the chucks under the three groove rods move to the periphery of the sample at the appointed position on the 96 pore plate during sampling, the electric push rod works to move upwards with the second plate, the chucks at the lower ends of the three groove rods can be pulled to approach by the three pull rods, so that the clamping of the sample is realized, the surrounding sample can not be touched, and the sampling effect is better;

2. the sampling unit is arranged, when the chucks under the three groove rods move to the periphery of a sample at a designated position on the 96-well plate, the CCD camera works, the holes around the sample can be shot, the moving position is detected, the accuracy of sampling is ensured, the annular light source is electrified and luminous to perform light compensation, the photographing effect is improved, the accuracy of the sampling position is further ensured, and the accuracy of sampling is improved;

3. be equipped with the fixed plate unit, after inserting the 96 orifice plate that has the sample in the board seat, rotate splint to 96 orifice plate's front side, under the spring action, push the slide and move backward, utilize the slide bar to pull splint to move backward, press from both sides the 96 orifice plate that has the sample tightly, realize the location, position location is more accurate, and efficiency is higher when the sample.

Drawings

FIG. 1 is a schematic perspective view of the present utility model;

FIG. 2 is a schematic view of a front cross-sectional structure of the present utility model;

FIG. 3 is a schematic view of a partial enlarged structure at A in FIG. 2 according to the present utility model;

fig. 4 is a schematic view of the internal structure of the spring case of the present utility model.

In the figure: 1 a bottom plate, 2 a lifting module, 3 a sampling unit, 31 a translation module, 32 a sliding seat, 33 a first plate, 34 a rod seat, 35 a groove rod, 36 an electric push rod, 37 a second plate, 38 a pull rod, 39 an annular light source, 310 a CCD camera, 4 a fixed plate unit, 41 a groove strip, 42 a plate seat, 43 a corner plate, 44 a back and forth movement module, 45 a spring box, 46 a sliding plate, 47 a sliding rod, 48 a spring, 49 a clamping plate, 5 a cushion column and 6 a conical seat.

Detailed Description

The technical solutions in the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model.

Referring to fig. 1-4, the present embodiment provides a 96-well plate sampling mechanism based on a CCD, which includes a bottom plate 1, a sampling unit 3 and a fixed plate unit 4, wherein the fixed plate unit 4 is installed at the upper end of the bottom plate 1; the middle part of the right side of the upper end of the bottom plate 1 is provided with a lifting module 2; the novel floor mat further comprises a mat column 5 and a conical seat 6, the mat column 5 is installed at four corners of the lower end of the floor mat 1, and the conical seat 6 is connected with the lower ends of the four mat columns 5 in a threaded mode. The length of the threaded connection of the upper end stud and the cushion column 5 can be adjusted by rotating the conical seat 6, so that the horizontal adjustment of the mechanism is realized, and the mechanism is more stable to use.

Wherein: the sampling unit 3 comprises a translation module 31 with one end connected to the lifting module 2 in a sliding way, a sliding seat 32 connected to the translation module 31 in a left-right sliding way, a first disk 33 arranged at the lower end of the sliding seat 32, three rod seats 34 with circumferences equally arranged at the lower end of the first disk 33, a groove rod 35 respectively connected to the lower ends of the rod seats 34 in a movable way, and a chuck arranged at the lower end of the groove rod 35; the sampling unit 3 further comprises an electric push rod 36 arranged at the upper end of the first disk 33, a second disk 37 arranged at the telescopic end of the electric push rod 36, and three pull rods 38 with the circumferences being equidistantly and movably connected to the lower end surface of the second disk 37, wherein the telescopic end of the electric push rod 36 passes through the first disk 33 downwards, and the other ends of the three pull rods 38 are respectively and movably connected to the groove rods 35; the sampling unit 3 further comprises an annular light source 39 and a CCD camera 310, the annular light source 39 is arranged at the lower end of the second disc 37, and the CCD camera 310 is arranged in the middle of the lower end of the second disc 37.

Wherein: the fixed plate unit 4 comprises a groove strip 41, a plate seat 42, a corner plate 43 and a front-back moving module 44, wherein the upper end of the bottom plate 1 is provided with two groove strips 41 in the front-back direction, the left side and the right side of the lower end of the plate seat 42 are respectively and slidably connected in the two groove strips 41, the middle part of the lower end of the plate seat 42 is provided with the corner plate 43, the front-back moving module 44 is arranged at the upper end of the bottom plate 1, and the moving end of the front-back moving module 44 is connected with the lower end of the corner plate 43; the fixed plate unit 4 further comprises a spring box 45, a sliding plate 46 and a sliding rod 47, wherein the spring box 45 is arranged on the front side of the middle part of the lower end of the plate seat 42, the sliding plate 46 is connected to the rear end of the interior of the spring box 45 in a front-back sliding manner, the sliding rod 47 is connected to the front end of the spring box 45 in a front-back sliding manner, and the rear end of the sliding rod 47 is connected to the middle part of the front end of the sliding plate 46; the fixed plate unit 4 further comprises a spring 48 and a clamping plate 49, wherein the front end of the spring 48 is connected to the front end of the interior of the spring box 45, the rear end of the spring 48 is connected to the front end of the sliding plate 46, the front end of the sliding rod 47 is rotatably connected with the clamping plate 49, and the front end of the clamping plate 49 is provided with a T-shaped handle.

The working principle of the utility model is as follows:

when the device is used, a 96-well plate with a sample is inserted into the plate seat 42, the movable clamp plate 49 of the T-shaped handle is pulled and rotated to the front side of the 96-well plate, the sliding plate 46 is pushed to move backwards under the action of the spring 48, the clamp plate 49 is pulled to move backwards by the sliding rod 47, and the 96-well plate with the sample is clamped to realize positioning;

then the back and forth moving module 44 moves to a proper position through the corner plate 43 with the plate seat 42, the lifting module 2 and the translation module 31 cooperate to move the clamping heads under the three groove rods 35 to the periphery of the sample at the appointed position on the 96-well plate, at the moment, the CCD camera 310 works to shoot the holes around the sample, the moving position is detected, the sampling precision is ensured, the annular light source 39 is electrified to emit light to compensate, the photographing effect is improved, and the accuracy of the sampling position is further ensured;

finally, the electric push rod 36 works to drive the second tray 37 to move upwards, the three pull rods 38 are used for pulling the chucks at the lower ends of the three groove rods 35 to approach, so that the clamping of samples is realized, after the clamping, the lifting module 2 and the translation module 31 cooperate to move the taken samples to a proper position, surrounding samples can not be touched during sampling, the sampling effect is better, and the use is more convenient.

The foregoing is only illustrative of the present utility model and is not to be construed as limiting the scope of the utility model, and all equivalent structures or equivalent flow modifications which may be made by the teachings of the present utility model and the accompanying drawings or which may be directly or indirectly employed in other related art are within the scope of the utility model.

Claims

1. A 96 orifice plate sampling mechanism based on CCD, its characterized in that: comprises a bottom plate (1), a sampling unit (3) and a fixed plate unit (4);

the middle part of the right side of the upper end of the bottom plate (1) is provided with a lifting module (2);

the sampling unit (3) comprises a translation module (31) with one end connected to the lifting module (2) in a sliding way, a sliding seat (32) connected to the translation module (31) in a sliding way left and right, a first disk (33) arranged at the lower end of the sliding seat (32), three rod seats (34) with circumferences being equidistantly arranged at the lower end of the first disk (33), a groove rod (35) respectively connected to the lower end of the rod seat (34) in a movable way, and a chuck arranged at the lower end of the groove rod (35); the device also comprises an electric push rod (36) arranged at the upper end of the first disc (33), a second disc (37) arranged at the telescopic end of the electric push rod (36) and three pull rods (38) with the circumferences being equidistantly and movably connected to the lower end surface of the second disc (37), wherein the telescopic end of the electric push rod (36) downwards passes through the first disc (33), and the other ends of the three pull rods (38) are respectively and movably connected to the groove rod (35);

the fixed plate unit (4) is arranged at the upper end of the bottom plate (1).

2. A CCD-based 96-well plate sampling mechanism according to claim 1, wherein: the sampling unit (3) further comprises an annular light source (39) and a CCD camera (310), the annular light source (39) is arranged at the lower end of the second disc (37), and the CCD camera (310) is arranged in the middle of the lower end of the second disc (37).

3. A CCD-based 96-well plate sampling mechanism according to claim 1, wherein: the fixed plate unit (4) comprises groove strips (41), a plate seat (42), angle plates (43) and a front-back moving module (44), the groove strips (41) in the front-back direction are arranged at the upper end of the bottom plate (1), the left side and the right side of the lower end of the plate seat (42) are respectively and slidably connected in the two groove strips (41), the angle plates (43) are arranged at the middle part of the lower end of the plate seat (42), the front-back moving module (44) is arranged at the upper end of the bottom plate (1), and the moving end of the front-back moving module (44) is connected with the lower end of the angle plates (43).

4. A CCD-based 96-well plate sampling mechanism according to claim 3, wherein: the fixed plate unit (4) further comprises a spring box (45), a sliding plate (46) and a sliding rod (47), the spring box (45) is installed on the front side of the middle of the lower end of the plate seat (42), the sliding plate (46) is connected to the inner rear end of the spring box (45) in a front-back sliding mode, the sliding rod (47) is connected to the front end of the spring box (45) in a front-back sliding mode, and the rear end of the sliding rod (47) is connected to the middle of the front end of the sliding plate (46).

5. The CCD-based 96-well plate sampling mechanism of claim 4, wherein: the fixed plate unit (4) further comprises a spring (48) and a clamping plate (49), the front end of the spring (48) is connected to the front end of the interior of the spring box (45), the rear end of the spring (48) is connected to the front end of the sliding plate (46), the front end of the sliding rod (47) is rotationally connected with the clamping plate (49), and the front end of the clamping plate (49) is provided with a T-shaped handle.

6. A CCD-based 96-well plate sampling mechanism according to claim 1, wherein: the novel floor mat is characterized by further comprising a mat column (5) and a conical seat (6), the mat column (5) is installed at four corners of the lower end of the bottom plate (1), and the conical seat (6) is connected with the lower ends of the four mat columns (5) in a threaded mode.