CN219168964U - Online real-time release detection device of pharmaceutical raw and auxiliary materials - Google Patents

Online real-time release detection device of pharmaceutical raw and auxiliary materials Download PDF

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Publication number
CN219168964U
CN219168964U CN202320042039.4U CN202320042039U CN219168964U CN 219168964 U CN219168964 U CN 219168964U CN 202320042039 U CN202320042039 U CN 202320042039U CN 219168964 U CN219168964 U CN 219168964U
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China
Prior art keywords
detection device
time release
auxiliary materials
release detection
pharmaceutical raw
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CN202320042039.4U
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Chinese (zh)
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江苏
王茺
董维付
许川
唐磊
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SICHUAN VSPEC TECHNOLOGIES Inc
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SICHUAN VSPEC TECHNOLOGIES Inc
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Abstract

The utility model discloses an online real-time release detection device for medicinal raw materials and auxiliary materials, which comprises a conveying mechanism, a controller, a near infrared spectrometer and an executing mechanism, wherein the conveying mechanism is used for conveying the medicinal raw materials and auxiliary materials packaged by a packaging bag; the controller is connected with a proximity switch; the near infrared spectrometer is connected with a near infrared probe; the execution mechanism is connected with the controller, and the near infrared probe is arranged on the execution mechanism; the controller is configured to drive the actuating mechanism to compact the packaging bag and the pharmaceutical raw and auxiliary materials in the packaging bag when the proximity switch detects the pharmaceutical raw and auxiliary materials, and drive the near infrared probe to collect near infrared spectrum information of the pharmaceutical raw and auxiliary materials, so that the operation is convenient and quick, and the labor intensity is reduced.

Description

Online real-time release detection device of pharmaceutical raw and auxiliary materials
Technical Field
The utility model relates to a detection device, in particular to an online real-time release detection device for medicinal raw materials and auxiliary materials.
Background
Real Time Release Testing (RTRT), defined as the ability to effectively combine measured material properties with process control, etc., and thereby evaluate and ensure intermediate and/or final product quality, can be used for actives, intermediates and finished products.
The real-time release detection can be used to replace the finished product detection, the key quality parameters can be measured when the key quality parameters are generated, and the quality control is shifted to the upstream.
At present, the pharmaceutical industry at home and abroad uses near infrared spectrum for links such as warehousing confirmation of raw and auxiliary materials, storage detection of raw and auxiliary materials, feeding detection and the like, and has the advantage that the content can be directly analyzed through glass or transparent polymer material packaging.
However, in the traditional near infrared spectrum detection method, a near infrared instrument is usually placed on a trolley, and is carried to a raw and auxiliary material stacking place, and near infrared spectrums of materials are acquired offline. The detection method has the defects of poor timeliness, high labor intensity and the like.
Disclosure of Invention
The utility model aims to provide an online real-time release detection device for medicinal raw materials and auxiliary materials, aiming at the defects of the prior art.
In order to achieve the above purpose, the present utility model adopts the following technical scheme:
on-line real-time release detection device for pharmaceutical raw materials and auxiliary materials comprises:
the conveying mechanism is used for conveying the medicinal raw materials packaged by the packaging bag;
a controller connected with a proximity switch;
the near infrared spectrometer is connected with a near infrared probe; and
the execution mechanism is connected with the controller, and the near infrared probe is arranged on the execution mechanism;
the controller is configured to drive the actuating mechanism to compact the packaging bag and the pharmaceutical raw and auxiliary materials in the packaging bag and drive the near infrared probe to collect spectrum information of the pharmaceutical raw and auxiliary materials when the proximity switch detects the pharmaceutical raw and auxiliary materials.
Further, the device also comprises a code scanner for scanning and recording the bar code information of the medicinal raw materials and auxiliary materials.
Further, the actuating mechanism comprises a cylinder, an extrusion part is arranged at the output end of the cylinder, and the extrusion part is used for compacting the packaging bag and the medicinal raw and auxiliary materials in the packaging bag.
Further, the near infrared probe is arranged at the output end of the air cylinder.
Further, the device also comprises a group of frames, and the conveying mechanism is arranged in the frames in a penetrating way;
the actuating mechanism is arranged on the frame and above the conveying mechanism.
Further, an electromagnetic valve and an air source triple piece connected with the air cylinder are arranged on the frame.
Further, the frame comprises a frame body and a side frame arranged at the upper end of the frame body, and the air cylinder is arranged on the side frame.
Further, a group of top beams are arranged on the side frames, and a mounting frame for fixing the air cylinder is arranged on the top beams.
Further, a damping spring shock absorber is also installed at the lower end of the frame.
Further, the proximity switch is a photoelectric sensor, a capacitive proximity switch, an ultrasonic proximity switch or a microwave proximity switch.
Compared with the prior art, the utility model has the following beneficial effects:
according to the online real-time release detection device, the medicinal raw materials and auxiliary materials to be detected can be placed on the conveying mechanism, when the proximity switch detects the medicinal raw materials and auxiliary materials, the executing mechanism compacts the packages of the medicinal raw materials and auxiliary materials, the near infrared probe is convenient to collect near infrared spectrum information of the medicinal raw materials and auxiliary materials, the operation is convenient and quick, and the labor intensity is reduced.
Drawings
FIG. 1 is a front view of an on-line real-time release detection device of the present utility model;
FIG. 2 is a side view of the online real-time release detection device of the present utility model;
FIG. 3 is a schematic view of a frame structure of the present utility model;
icon: 10-rack, 100-rack body, 101-side frame, 1010-connecting plate, 102-top beam, 1020-mounting rack, 103-damping spring damper, 20-cabinet, 200-extrusion part, 201-near infrared spectrometer, 2010-near infrared probe, 202-actuator, 203-solenoid valve, 204-air source triplet, 205-controller, 206-industrial computer, 207-air conditioner, 30-conveying mechanism.
Detailed Description
The utility model is further illustrated by the following examples in conjunction with the accompanying drawings:
referring to fig. 1 to 3, the present utility model discloses an online real-time release detection device, which comprises a frame 10, a cabinet 20 and a conveying mechanism 30.
The conveying mechanism 30 adopts a horizontal conveying belt structure, is arranged in the frame 10 in a penetrating way, and the cabinet 20 is arranged on the frame 10.
The conveying mechanism 30 is used for conveying the medicinal raw materials and auxiliary materials packaged by the packaging bag, namely, the medicinal raw materials and auxiliary materials sequentially pass through the lower part of the cabinet 20 under the driving of the conveying mechanism 30.
Referring to fig. 1 and 2, the cabinet 20 is provided with a near infrared spectrometer 201, a controller 205, an industrial computer 206, a display, an air conditioner 207, and the like.
A proximity switch may be mounted on the housing 10 or the cabinet 20, and may be detected by the proximity switch when the pharmaceutical raw materials pass under the cabinet 20, so it is easy to understand that the proximity switch may select one or more of a photoelectric sensor, a capacitive proximity switch, an ultrasonic proximity switch, or a microwave proximity switch, and the proximity switch is connected to the controller 205.
Wherein near infrared spectrometer 201 is connected to near infrared probe 2010.
In addition, the machine frame 10 is further provided with an actuating mechanism 202, the actuating mechanism 202 is used for compacting the pharmaceutical raw materials with packaging bags, and displacement is required to be generated in the action process of the actuating mechanism 202, so it is easy to understand that the actuating mechanism 202 can adopt a cylinder, a hydraulic cylinder, a rack and pinion driving mechanism or a linear motion mechanism such as a linear motor, and the near infrared probe 2010 is arranged on the actuating mechanism 202.
The controller 205 is connected to the near infrared spectrometer 201, the actuator 202, and the conveying mechanism 30.
According to a preset program instruction, when the proximity switch detects the medicinal raw and auxiliary materials, the controller 205 drives the conveying mechanism 30 to stop rotating, drives the executing mechanism 202 to move towards the surface of the conveying mechanism 30 at the lower side, compacts the packaging bag and the medicinal raw and auxiliary materials in the packaging bag, and facilitates the near infrared probe 2010 to collect near infrared spectrum information of the medicinal raw and auxiliary materials.
In addition, the above near infrared spectrum information is transmitted to a database in the industrial computer 206, in addition, near infrared spectrum sample information of various medicinal raw and auxiliary materials samples is stored in the industrial computer 206, information comparison is performed through a preset algorithm, the current medicinal raw and auxiliary materials are identified, qualitative and classified, and the part can adopt the prior art in the industry and is not described herein.
Comparing the analysis result of the sample with the read pre-medicinal raw and auxiliary material information through the industrial computer 206, and if the same material is confirmed, releasing the conveying mechanism 30 to enter the next production link; if the material analysis result is not consistent with the material information, an audible and visual alarm can be generated, and meanwhile, a cylinder or a mechanical arm and the like can be adopted to push the material into the temporary storage area.
In addition, in some embodiments, a code scanner may be further provided, and the code scanner may be installed on the conveying mechanism 30, the rack 10 or the cabinet 20, and is used to scan and record the bar code (or two-dimensional code) information of the pharmaceutical raw materials and auxiliary materials, and record the information into the database of the industrial computer 206, so that each group of pharmaceutical raw materials and auxiliary materials scanned by near infrared spectrum has independent coding information, so as to facilitate distinguishing, checking and summarizing.
Referring to fig. 1 and 2, in one embodiment, the actuator 202 includes a cylinder, an output end of the cylinder is provided with an extrusion component 200, the extrusion component 200 is used for compacting the packaging bag and the pharmaceutical raw materials and auxiliary materials in the packaging bag, and in addition, to facilitate collection of spectral information, the near infrared probe 2010 is provided at the output end of the cylinder.
Referring to fig. 1, a PLC controller, a solenoid valve 203, a gas source triple 204, etc. connected to the cylinder are provided on the frame 10.
The frame 10 comprises a frame body 100 and a side frame 101 arranged at the upper end of the frame 10 body, wherein a group of top beams 102 are arranged on the side frame 101 through a connecting plate 1010, a mounting frame 1020 for fixing the air cylinder is arranged on the top beams 102, and the upper end of the air cylinder is fixedly arranged on the mounting frame 1020.
In addition, a damping spring shock absorber 103 is further installed at the lower end of the frame 10, so that the running stability of the whole equipment is improved.
It should be noted that the positional or positional relationship indicated by the terms such as "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. are based on the positional and positional relationship shown in the drawings, are merely for convenience of describing the present utility model and simplifying the description, and do not indicate or imply that the apparatus or element to be referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present utility model.
In the description of the present utility model, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present utility model will be understood in specific cases by those of ordinary skill in the art.
The above embodiments are only for illustrating the technical solution of the present utility model, and not for limiting the scope of the present utility model. It will be apparent that the described embodiments are merely some, but not all, embodiments of the utility model. Based on these embodiments, all other embodiments that may be obtained by one of ordinary skill in the art without inventive effort are within the scope of the utility model.

Claims (10)

1. On-line real-time release detection device for pharmaceutical raw materials and auxiliary materials, which is characterized by comprising:
the conveying mechanism is used for conveying the medicinal raw materials packaged by the packaging bag;
a controller connected with a proximity switch;
the near infrared spectrometer is connected with a near infrared probe; and
the execution mechanism is connected with the controller, and the near infrared probe is arranged on the execution mechanism;
the controller is configured to drive the executing mechanism to compact the packaging bag and the medicinal raw and auxiliary materials in the packaging bag when the proximity switch detects the medicinal raw and auxiliary materials; and driving the near infrared probe to acquire the spectrum information of the pharmaceutical raw materials and auxiliary materials.
2. The pharmaceutical raw and auxiliary material online real-time release detection device according to claim 1, wherein: the device also comprises a code scanner for scanning and recording the bar code information of the pharmaceutical raw materials and auxiliary materials.
3. The pharmaceutical raw and auxiliary material online real-time release detection device according to claim 1 or 2, characterized in that: the actuating mechanism comprises a cylinder, wherein an extrusion part is arranged at the output end of the cylinder and used for compacting the packaging bag and the medicinal raw and auxiliary materials in the packaging bag.
4. The pharmaceutical raw and auxiliary materials online real-time release detection device according to claim 3, wherein: the near infrared probe is arranged at the output end of the air cylinder.
5. The pharmaceutical raw and auxiliary materials online real-time release detection device according to claim 3, wherein: the conveying mechanism is arranged in the rack in a penetrating manner;
the actuating mechanism is arranged on the frame and above the conveying mechanism.
6. The on-line real-time release detection device for pharmaceutical raw materials and auxiliary materials according to claim 5, wherein the on-line real-time release detection device is characterized in that: and the electromagnetic valve and the air source triplet are connected with the air cylinder and are arranged on the frame.
7. The on-line real-time release detection device for pharmaceutical raw materials and auxiliary materials according to claim 5, wherein the on-line real-time release detection device is characterized in that: the frame comprises a frame body and a side frame arranged at the upper end of the frame body, and the air cylinder is arranged on the side frame.
8. The on-line real-time release detection device for pharmaceutical raw materials and auxiliary materials according to claim 7, wherein the on-line real-time release detection device is characterized in that: the side frame is provided with a group of top beams, and the top beams are provided with mounting frames for fixing the air cylinders.
9. The on-line real-time release detection device for pharmaceutical raw materials and auxiliary materials according to claim 7, wherein the on-line real-time release detection device is characterized in that: the lower end of the frame is also provided with a damping spring shock absorber.
10. The pharmaceutical raw and auxiliary material online real-time release detection device according to claim 1, wherein: the proximity switch is a photoelectric sensor, a capacitance proximity switch, an ultrasonic proximity switch or a microwave proximity switch.
CN202320042039.4U 2023-01-06 2023-01-06 Online real-time release detection device of pharmaceutical raw and auxiliary materials Active CN219168964U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202320042039.4U CN219168964U (en) 2023-01-06 2023-01-06 Online real-time release detection device of pharmaceutical raw and auxiliary materials

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202320042039.4U CN219168964U (en) 2023-01-06 2023-01-06 Online real-time release detection device of pharmaceutical raw and auxiliary materials

Publications (1)

Publication Number Publication Date
CN219168964U true CN219168964U (en) 2023-06-13

Family

ID=86675259

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202320042039.4U Active CN219168964U (en) 2023-01-06 2023-01-06 Online real-time release detection device of pharmaceutical raw and auxiliary materials

Country Status (1)

Country Link
CN (1) CN219168964U (en)

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