CN219125211U

CN219125211U - Cell freezing box for monoclonal antibody preparation

Info

Publication number: CN219125211U
Application number: CN202223215799.5U
Authority: CN
Inventors: 吴培; 王蒙; 张云; 赵爱兵; 王姝洁
Original assignee: Anhui Yiwo Biomedical Technology Co ltd
Current assignee: Anhui Yiwo Biomedical Technology Co ltd
Priority date: 2022-12-01
Filing date: 2022-12-01
Publication date: 2023-06-06
Anticipated expiration: 2032-12-01

Abstract

The utility model relates to a cell freezer for monoclonal antibody preparation, and belongs to the technical field of cell freezers. The method mainly solves the problem that the test tube is inconvenient to segment and protect, and provides the following technical scheme. The test tube box comprises a lower box body, the top of lower box body is provided with the box body, the inner wall department of lower box body can be dismantled and is connected with down the baffle, the inner wall department of going up the box body can be dismantled and be connected with the baffle, the top of going up the baffle and the bottom of lower baffle all can be dismantled and be connected with the test tube cover. According to the utility model, through the mutual matching among the lower partition plate, the upper partition plate, the limiting seat and the test tube sleeve, the protection and segmentation of the test tubes can be effectively ensured when the device stores the test tubes, and the damage of the test tubes caused by the collision among the test tubes when the test tubes are used is avoided, so that the monoclonal antibodies stored in the test tubes leak, and the storage effect of the antibodies is further influenced.

Description

Cell freezing box for monoclonal antibody preparation

Technical Field

The utility model relates to the technical field of cell freezers, in particular to a cell freezer for monoclonal antibody preparation.

Background

The monoclonal antibody is an antibody which is produced by single B cell clone and is highly uniform and only aimed at a certain specific epitope, when the antibody cells are transported and stored, a freezing box is needed to freeze and store the cells, so that the situation that the cells are active due to higher temperature and then die in long-time storage is avoided, the existing freezing box generally freezes liquid nitrogen, and when a test tube is fixed in the freezing box, the test tube is inconvenient to partition and protect, and the test tube is easy to damage due to mutual collision among the test tubes, so that the storage effect of the monoclonal antibody is affected.

For this purpose we propose a cell freezer for monoclonal antibody production.

Disclosure of Invention

The utility model aims to provide a cell freezer for monoclonal antibody preparation, which solves the problem that the prior art is inconvenient to segment and protect a test tube.

In order to solve the technical problems, the utility model provides the following technical scheme: the utility model provides a cell freezer for monoclonal antibody preparation, includes the box down, the top of box is provided with the box down, the inner wall department of box can be dismantled and be connected with down the baffle down, the inner wall department of going up the box can be dismantled and be connected with the baffle, the top of going up the baffle and the bottom of baffle all can be dismantled and be connected with test tube cover down, the feed liquor pipe is all installed to the curb plate of box and last box down, the box includes the basic material layer down, the fixed surface of basic material layer is connected with the insulating layer.

Further, the inner walls of the lower box body and the upper box body are fixedly connected with limiting seats, and the lower partition plate and the upper partition plate are respectively fixed with the limiting seats through magic tapes.

Further, the surfaces of the lower box body and the upper box body are fixedly connected with connecting plates, locking seats are sleeved on the surfaces of the connecting plates, and the connecting plates and the locking seats are fixed through bolts.

Further, the surface of the test tube sleeve is provided with a thread groove, the bottoms of the lower partition plate and the upper partition plate are fixedly connected with a thread sleeve, and the test tube sleeve is in threaded connection with the thread sleeve through the thread groove.

Further, the surface of the heat insulation layer is fixedly connected with a protective layer, and the protective layer is made of iron.

Further, the surfaces of the lower partition plate and the upper partition plate are fixedly connected with sealing gaskets, and the sealing gaskets are tightly attached to the lower box body and the upper box body.

Compared with the prior art, the utility model has the following beneficial effects:

(1) According to the utility model, through the mutual matching among the lower partition plate, the upper partition plate, the limiting seat and the test tube sleeve, the protection and segmentation of the test tubes can be effectively ensured when the device stores the test tubes, and the damage of the test tubes caused by the collision among the test tubes when the test tubes are used is avoided, so that the monoclonal antibodies stored in the test tubes leak, and the storage effect of the antibodies is further influenced.

(2) According to the utility model, the heat insulation effect of the structure during freezing storage is effectively improved through the arranged heat insulation layer, the strength of the whole structure is effectively improved through the arranged protective layer, and the stability of the structure during use is ensured.

Drawings

The accompanying drawings are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate the utility model and together with the embodiments of the utility model, serve to explain the utility model. In the drawings:

FIG. 1 is a schematic perspective view of an embodiment of the present utility model;

FIG. 2 is a cross-sectional view of one embodiment of the present utility model;

FIG. 3 is a schematic diagram of the connection of the lower and upper cases according to an embodiment of the present utility model;

fig. 4 is a schematic structural diagram of a case according to an embodiment of the present utility model.

In the figure: 1. a lower box body; 101. a base material layer; 102. a thermal insulation layer; 103. a protective layer; 2. an upper case; 3. a lower partition plate; 4. an upper partition plate; 5. a limit seat; 6. a test tube sleeve; 7. a liquid inlet pipe; 8. a connecting plate; 9. a locking seat; 10. a sealing gasket; 11. a thread groove; 12. and (5) a threaded sleeve.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

Referring to fig. 1-4, the present utility model provides the following technical solutions: a cell freezer for monoclonal antibody preparation, including lower box 1, the top of lower box 1 is provided with box 2, the inner wall department of lower box 1 can be dismantled and is connected with down baffle 3, the inner wall department of upper box 2 can be dismantled and be connected with upper baffle 4, the top of upper baffle 4 and the bottom of lower baffle 3 all can be dismantled and be connected with test tube cover 6, feed liquor pipe 7 is all installed to the curb plate of lower box 1 and upper box 2, lower box 1 includes basic material layer 101, the fixed surface of basic material layer 101 is connected with insulating layer 102, when using the structure, through setting up test tube cover 6 to a plurality ofly, and then effectually guaranteed to deposit a plurality of test tubes, in the use to the structure, through the effect that lower baffle 3 and upper baffle 4 that sets up play the support respectively, the overhead effect after carrying out the house has been guaranteed to the test tube.

According to fig. 2, the inner walls of the lower case 1 and the upper case 2 are fixedly connected with a limiting seat 5, the lower partition plate 3 and the upper partition plate 4 are respectively fixed with the limiting seat 5 through magic tapes, and in the use of the lower case 1 and the upper case 2, the limiting seat 5 plays a role in limiting and fixing, so that the stability of the lower partition plate 3 placed in the lower case 1 and the upper partition plate 4 placed in the upper case 2 is ensured.

According to fig. 3, the surfaces of the lower case 1 and the upper case 2 are fixedly connected with a connecting plate 8, the surfaces of the connecting plate 8 are sleeved with a locking seat 9, the connecting plate 8 and the locking seat 9 are fixed through bolts, and when the device is used, the connecting plate 8 is tightly attached and then fixed through the locking seat 9, so that the attaching effect of the top of the lower case 1 and the bottom of the upper case 2 is ensured.

According to fig. 2, the surface of the test tube sleeve 6 is provided with a thread groove 11, the bottom of the lower partition plate 3 and the bottom of the upper partition plate 4 are fixedly connected with a thread sleeve 12, the test tube sleeve 6 is in threaded connection with the thread sleeve 12 through the thread groove 11, and when the test tube sleeve is used, the test tube sleeve 6 is in threaded connection with the thread sleeve 12 through the thread groove 11, so that the fixing and the dismounting of the test tube sleeve 6 are effectively ensured, and the replacement convenience is ensured when the test tube sleeve 6 is damaged.

According to fig. 4, the surface of the insulating layer 102 is fixedly connected with the protective layer 103, the protective layer 103 is made of iron, and when the insulating layer is used, the whole structure is effectively ensured to be damaged due to external scratch through the arranged protective layer 103.

According to fig. 3, the sealing gaskets 10 are fixedly connected to the surfaces of the lower partition plate 3 and the upper partition plate 4, the sealing gaskets 10 are tightly attached to the lower box 1 and the upper box 2, and when the whole structure is used, the sealing effect of the structure during the use is ensured by the arranged sealing gaskets 10, so that the occurrence of the infiltration condition of liquid nitrogen during the use is avoided.

The working principle of the utility model is as follows: when carrying out cold-stored depositing to the test tube of depositing monoclonal antibody, through placing down baffle 3 in lower box 1 spacing seat 5's top fixed, then insert test tube in test tube cover 6, then place the top of baffle 3 down with last baffle 4, make the test tube cover 6 cover at last baffle 4 top at the surface of test tube, thereby effectually play the effect of protection to the test tube, then with last box 2 cover at the surface of box 1 down, make connecting plate 8 laminate each other, then with locking seat 9 cover at connecting plate 8's surface, and fix it through the bolt, and then guaranteed laminating each other between the connecting plate 8, the effectual inseparable of connecting between lower box 1 and the last box 2 of having guaranteed, then carry liquid nitrogen in lower box 1 and the last box 2 through feed liquor pipe 7, thereby reach the effect of carrying out the freezing and depositing to the test tube, effectively guaranteed the effect of depositing of monoclonal, then in the use of box 1 and last box 2, through the effectual heat-proof layer 102 that sets up, the whole protection layer that has effectively improved through the thermal-insulated structure of depositing when setting up.

It is noted that relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.

Finally, it should be noted that: the foregoing description is only a preferred embodiment of the present utility model, and the present utility model is not limited thereto, but it is to be understood that modifications and equivalents of some of the technical features described in the foregoing embodiments may be made by those skilled in the art, although the present utility model has been described in detail with reference to the foregoing embodiments. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present utility model should be included in the protection scope of the present utility model.

Claims

1. A cell freezer for monoclonal antibody production, characterized in that: including lower box (1), the top of lower box (1) is provided with box (2), the inner wall department of lower box (1) can be dismantled and be connected with lower baffle (3), the inner wall department of going up box (2) can be dismantled and be connected with upper baffle (4), the top of upper baffle (4) and the bottom of lower baffle (3) all can be dismantled and be connected with test tube cover (6), feed liquor pipe (7) are all installed to the curb plate of lower box (1) and last box (2), lower box (1) include basic material layer (101), the fixed surface of basic material layer (101) is connected with insulating layer (102).

2. A cell freezer for monoclonal antibody production according to claim 1, wherein: the inner walls of the lower box body (1) and the upper box body (2) are fixedly connected with limiting seats (5), and the lower partition plate (3) and the upper partition plate (4) are respectively fixed with the limiting seats (5) through magic tapes.

3. A cell freezer for monoclonal antibody production according to claim 1, wherein: the surface of lower box (1) and last box (2) all fixedly connected with connecting plate (8), locking seat (9) have been cup jointed on the surface of connecting plate (8), connecting plate (8) and locking seat (9) are fixed through the bolt.

4. A cell freezer for monoclonal antibody production according to claim 1, wherein: the surface of test tube cover (6) has seted up screw thread groove (11), the bottom of lower baffle (3) and the bottom of last baffle (4) all fixedly connected with screw thread cover (12), test tube cover (6) pass through screw thread groove (11) and screw thread cover (12) threaded connection.

5. A cell freezer for monoclonal antibody production according to claim 1, wherein: the surface of the heat insulation layer (102) is fixedly connected with a protective layer (103), and the protective layer (103) is made of iron.

6. A cell freezer for monoclonal antibody production according to claim 1, wherein: the surface of the lower partition plate (3) and the surface of the upper partition plate (4) are fixedly connected with sealing gaskets (10), and the sealing gaskets (10) are tightly attached to the lower box body (1) and the upper box body (2).