CN215602868U - Mesenchymal stem cell cryopreservation protection device - Google Patents

Mesenchymal stem cell cryopreservation protection device Download PDF

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CN215602868U
CN215602868U CN202122502235.9U CN202122502235U CN215602868U CN 215602868 U CN215602868 U CN 215602868U CN 202122502235 U CN202122502235 U CN 202122502235U CN 215602868 U CN215602868 U CN 215602868U
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fixedly connected
sleeve
mesenchymal stem
storage tube
clamping plate
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高志
叶翠
万文昊
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Chengdu Gaocuiyinhe Biotechnology Co ltd
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Chengdu Gaocuiyinhe Biotechnology Co ltd
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Abstract

The utility model discloses a mesenchymal stem cell cryopreservation protection device in the technical field of medical equipment, which comprises a protection box body, an electromagnetic valve, a refrigeration compressor and a heater, the storage tube is used for storing the mesenchymal stem cell jelly, the surface of the storage tube is provided with a sealing sleeve for sealing the inner wall of the storage tube, after the mesenchymal stem cells are stored in the storage tube of the device, the storage tube is arranged in the protective box body through the first clamp and the second clamp, after the sealing cover seals the protection box body, the refrigeration compressor can refrigerate the storage pipe and the protection box body through the refrigeration pipe, thereby realizing the freezing preservation, and the protective box body and the sealing cover are both arranged into a double-layer structure and the inside is provided with vacuum, improving the heat insulation effect, meanwhile, the inside of the protective box body and the inside of the sealing cover are respectively and fixedly connected with a heat insulation sleeve and a heat insulation pad, so that the heat insulation effect is further improved.

Description

Mesenchymal stem cell cryopreservation protection device
Technical Field
The utility model relates to the technical field of medical equipment, in particular to a mesenchymal stem cell cryopreservation protection device.
Background
Mesenchymal stem cells are pluripotent stem cells that have all of the commonalities of stem cells, namely self-renewal and multipotential differentiation capacity. The application is most in clinical application, and the combined application with hematopoietic stem cells can improve the success rate of transplantation and accelerate hematopoietic reconstruction. After a patient receives a large dose of chemotherapy, the mesenchymal stem cells and the hematopoietic stem cells are input together, so that the recovery time of the blood cells of the patient can be obviously accelerated, and the chemotherapy is safe and has no adverse reaction.
Most of current mesenchymal stem cell storage need be stored through freezing, but current freezing storage device does not have a section specially just to the mesenchymal stem cell storage to refrigeration effect is also not good, and easy collision takes place when mesenchymal stem cell stores simultaneously and causes the damage, and mesenchymal stem cell needs water bath heating when freezing back use in addition, leads to still needing other equipment cooperations to use, for this reason, we provide a mesenchymal stem cell cryopreservation protection device.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide a mesenchymal stem cell cryopreservation protection device to solve the problems in the background technology.
In order to achieve the purpose, the utility model provides the following technical scheme: the utility model provides a protection device is deposited to mesenchymal stem cell freezing, includes protection box, storage tube, solenoid valve, compressor and heater, the storage tube is used for storing mesenchymal stem cell and freezes, the surface mounting of storage tube has the seal cover to be used for sealing up the storage tube inner wall, the storage tube is fixed inside the protection box through anchor clamps one and two centre grippings of anchor clamps, the surface of protection box is installed sealed lid through the screw thread and is used for keeping warm to the inside sealed of protection box, the fixed surface of sealed lid is connected with compressor and is used for refrigerating, it runs through in inserting the inside fixed storage tube of protection box to install refrigeration pipe and refrigeration pipe on the compressor.
Preferably, the first clamp comprises a first sleeve, a first connecting spring, a first telescopic rod and a first clamping plate, the first sleeve is fixedly connected to the inner wall of the protective box body, the first telescopic rod is inserted into the first sleeve, and the first clamping plate is fixedly connected to the surface of the first telescopic rod;
the second clamp comprises a second sleeve, a second connecting spring, a second telescopic rod and a second clamping plate, the second sleeve is fixedly connected to the inner wall of the protective box body, the second telescopic rod is inserted into the second sleeve, and the second clamping plate is fixedly connected to the surface of the second telescopic rod;
the first clamping plate and the second clamping plate are both arranged to be of V-shaped structures, an opening is formed in the middle of the first clamping plate, the size of the opening is matched with that of the second clamping plate, and the second clamping plate is located at the same horizontal height of the opening formed in the middle of the first clamping plate.
Preferably, the surfaces of the first telescopic rod and the first clamping plate are fixedly connected with a first protection pad and a second protection pad respectively.
Preferably, the surfaces of the first sleeve and the second sleeve are provided with sliding grooves, the surfaces of the first telescopic rod and the second telescopic rod are fixedly connected with a first limiting rod and a second limiting rod respectively, and the first limiting rod and the second limiting rod are inserted into the sliding grooves formed in the surfaces of the first sleeve and the second sleeve respectively.
Preferably, a first connecting spring is fixedly connected inside the first sleeve, one end of the first connecting spring is fixedly connected to the inner wall of the first sleeve, and the other end of the first connecting spring is fixedly connected to the surface of the first telescopic rod;
and the inside of the second sleeve is fixedly connected with a second connecting spring, one end of the second connecting spring is fixedly connected to the inner wall of the second sleeve, and the other end of the second connecting spring is fixedly connected to the surface of the second telescopic rod.
Preferably, the bottom fixedly connected with solenoid valve of holding tube, the bottom surface central point of protection box puts fixedly connected with heating cabinet, and the surface of heating cabinet is provided with circular opening and circular open-ended outside fixedly connected with blotter, the collecting tray is installed through the screw thread to the bottom surface of heating cabinet, and the opening below fixedly connected with baffle that the heating cabinet surface set up simultaneously, heating cabinet internally mounted has the heater.
Preferably, the bottom surface of the protection box body is fixedly connected with supporting legs.
Preferably, the wall shell of the protection box body is set to be in a double-layer structure and is internally set to be in vacuum, the inner wall fixedly connected with heat preservation sleeve of the protection box body is set to be in a double-layer structure and is internally set to be in vacuum, and the inner wall fixedly connected with heat preservation pad of the sealing cover is arranged.
Compared with the prior art, the utility model has the beneficial effects that:
1. after mesenchymal stem cells are stored in the storage tube of the device, the storage tube is arranged in the protective box body through the first clamp and the second clamp, so that after the sealing cover is sealed in the protective box body, the refrigeration compressor can refrigerate the storage tube and the protective box body through the refrigeration tube, thereby realizing freezing storage, the protective box body and the sealing cover are both arranged into a double-layer structure, and the interiors of the protective box body and the sealing cover are provided with vacuum, thereby improving the heat insulation effect;
2. the storage tubes with different radiuses can be installed and fixed by fixing the first clamp and the second clamp, and the first clamp and the second clamp can buffer and protect the storage tubes after clamping and fixing the storage tubes;
3. this device can take out mesenchymal stem cell fast through the solenoid valve of storage tube bottom installation to the storage tube is at the internal fixed back of protective housing, and the mesenchymal stem cell of taking out can directly fall into the catch tray in, can carry out water bath heating to mesenchymal stem cell fast through the catch tray, conveniently takes out the back and uses fast.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic sectional view of the structure of the present invention;
FIG. 3 is an exploded view of the structure of the present invention;
FIG. 4 is a schematic cross-sectional view of a portion of the structure of the present invention;
FIG. 5 is an exploded view of a clamp according to the present invention;
fig. 6 is an exploded view of the second structure of the clamp of the present invention.
In the figure: 1. a protective box body; 2. a thermal insulation sleeve; 3. a first clamp; 31. a first sleeve; 32. a first connecting spring; 33. a first telescopic rod; 34. a first clamping plate; 35. a first protection pad; 36. a first limiting rod; 4. a second clamp; 41. a second sleeve; 42. a second connecting spring; 43. a second telescopic rod; 44. a second clamping plate; 45. a second protection pad; 46. a second limiting rod; 5. a storage tube; 6. sealing sleeves; 7. an electromagnetic valve; 8. a sealing cover; 9. a heat-insulating pad; 10. a refrigeration compressor; 11. a refrigeration pipe; 12. a heating box; 13. a heater; 14. a collection tray; 15. a cushion pad; 16. a baffle plate; 17. and (5) supporting legs.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example one
Referring to fig. 1-6, the present invention provides a technical solution:
a mesenchymal stem cell cryopreservation protection device comprises a storage tube 5, the storage tube 5 is inserted between a first clamp 3 and a second clamp 4 fixed inside a protection box body 1, the second clamp 4 is stored inside the protection box body 1 through the first clamp 3 and the second clamp 4, the protection box body 1 is mounted through a sealing cover 8, threads are arranged on the surface of the protection box body 1 and are meshed with the threads arranged on the inner wall of the sealing cover 8, the sealing cover 8 can be mounted on the protection box body 1 through the threads, the sealing cover 8 is prevented from falling off from the protection box body 1 easily, the protection box body 1 is sealed through the sealing cover 8, and mesenchymal stem cells stored in the storage tube 5 can be better stored;
simultaneously, the fixed surface of sealed lid 8 is connected with compressor 10, and install refrigeration pipe 11 on compressor 10, refrigeration pipe 11 runs through sealed lid 8 and inserts inside protection box 1, and install when protection box 1 is inside through anchor clamps 3 and anchor clamps two 4 when storage tube 5, refrigeration pipe 11 just can insert inside storage tube 5, and seal cover 6 is installed through the screw thread on storage tube 5's surface, seal cover 6 is used for 5 inside sealings of storage tube, the surface of seal cover 6 is provided with the opening and is used for running through of refrigeration pipe 11 simultaneously, make refrigeration pipe 11 can insert inside storage tube 5, improve refrigeration speed and refrigeration effect, thereby the mesenchymal stem cell of storing in the storage tube 5 carries out freezing protection.
Example two
Referring to fig. 1-6, on the basis of the first embodiment, the present invention provides a technical solution:
a mesenchymal stem cell cryopreservation protection device is characterized in that when a storage tube 5 is clamped and fixed through a first clamp 3 and a second clamp 4, a first clamp 34 and a second clamp 44 abut against the surface of the storage tube 5, the first clamp 34 and the second clamp 44 are both in a V-shaped structure, an opening is formed in the middle of the first clamp 34, the size of the opening is matched with that of the second clamp 44, and the second clamp 44 is located at the same horizontal height of the opening formed in the middle of the first clamp 34, so that the second clamp 44 can be inserted between the first clamps 34, and the first clamp 34 and the second clamp 44 can clamp and fix the storage tubes 5 with different radiuses;
the surfaces of the first clamping plate 34 and the second clamping plate 44 are fixedly connected with a first protection pad 35 and a second protection pad 45 respectively, so that the phenomenon that when the first clamping plate 34 and the second clamping plate 44 clamp and fix the storage tube 5, the storage tube 5 is broken to further cause the falling of mesenchymal stem cells stored inside the storage tube 5 is avoided;
meanwhile, the first clamping plate 34 and the second clamping plate 44 are respectively arranged in the first sleeve 31 and the second sleeve 41 through the first telescopic rod 33 and the second telescopic rod 43, the first sleeve 31 and the second sleeve 41 are both fixedly connected on the inner wall of the protection box body 1, and a first connecting spring 32 is fixedly connected inside the first sleeve 31, one end of the first connecting spring 32 is fixedly connected on the inner wall of the first sleeve 31, the other end of the first connecting spring 32 is fixedly connected on the surface of a first telescopic rod 33, so that the telescopic rod one 33 can slide on the inner wall of the sleeve one 31 to press the connecting spring one 32, the sliding of the first telescopic rod 33 can be reset through the elastic force of the first connecting spring 32, meanwhile, the surface of the first sleeve 31 is provided with a sliding chute, the surface of the first telescopic rod 33 is fixedly connected with a first limit rod 36, the size of the first limit rod 36 is matched with the size of the sliding chute arranged on the surface of the first sleeve 31, the first limiting rod 36 can slide in a sliding groove formed in the surface of the first sleeve 31 and limit the first telescopic rod 33;
similarly, the inside of the second sleeve 41 is fixedly connected with a second connecting spring 42, one end of the second connecting spring 42 is fixedly connected to the inner wall of the second sleeve 41, the other end of the second connecting spring 42 is fixedly connected to the surface of the second telescopic rod 43, so that the second telescopic rod 43 can slide and extrude the second connecting spring 42 on the inner wall of the second sleeve 41, the sliding of the second telescopic rod 43 can be reset through the elastic action of the second connecting spring 42, meanwhile, the surface of the second sleeve 41 is provided with a sliding groove, the surface of the second telescopic rod 43 is fixedly connected with a second limiting rod 46, the size of the second limiting rod 46 is matched with the size of the sliding groove formed in the surface of the second sleeve 41, so that the second telescopic rod 43 can slide in the sliding groove formed in the surface of the second sleeve 41 and limit the second clamping plate 44;
further make anchor clamps 3 and anchor clamps two 4 can carry out the centre gripping to the storage tube 5 of different radius sizes fixed and step up to when storage tube 5 received rocking of small range in protection box 1, can cushion through anchor clamps 3 and anchor clamps two 4, thereby improve the fixed protectiveness to storage tube 5.
EXAMPLE III
Referring to fig. 1-6, on the basis of the second embodiment, the present invention provides a technical solution:
a mesenchymal stem cell cryopreservation protection device is characterized in that the bottom end of a storage tube 5 is fixedly connected with an electromagnetic valve 7, the central position of the bottom end surface of a protection box body 1 is fixedly connected with a heating box 12, the surface of the heating box 12 is provided with a circular opening, and the outer side of the circular opening is fixedly connected with a buffer cushion 15, so that when the storage tube 5 is inserted into the protection box body 1 for fixation, when the electromagnetic valve 7 is abutted against the surface of the buffer cushion 15, a user can determine that the storage tube 5 is stably fixed, and meanwhile, the buffer cushion 15 can be used for placing the storage tube 5 to smash the surface of the heating box 12 in the insertion process to cause bottom damage;
collecting tray 14 is installed through the screw thread to the bottom surface of heating cabinet 12, simultaneously opening below fixedly connected with baffle 16 that heating cabinet 12 surface set up, baffle 16 sets up to leaking hopper-shaped, make solenoid valve 7 open the back, the mesenchymal stem cells of storage in the storage tube 5 can flow into in heating cabinet 12 through baffle 16, rethread heating cabinet 12 falls into on collecting tray 14, the person of facilitating the use takes out, and install a plurality of heater 13 of group on the inner wall of heating cabinet 12, can heat heating cabinet 12 inside, and collecting tray 14 when the installation inside need fill with normal saline, collecting tray 14 need guarantee after installing on heating cabinet 12 that heater 13 can insert in the normal saline, thereby conveniently heat normal saline, further carry out water bath heating to the cell in the normal saline, conveniently take out the back alright quick use.
Example four
Referring to fig. 1-6, on the basis of the third embodiment, the present invention provides a technical solution:
the utility model provides a protection device is cryopreserved to mesenchymal stem cell, the bottom fixed surface of protection box 1 is connected with three groups and is the supporting leg 17 that the circumference distributes, will protect box 1 to erect through supporting leg 17, makes things convenient for the installation of catch tray 14 to dismantle.
EXAMPLE five
Referring to fig. 1-6, on the basis of the first embodiment, the present invention provides a technical solution:
the utility model provides a protection device is deposited to mesenchymal stem cell freezing, the walling of protection box 1 sets up to bilayer structure and inside and sets up to the vacuum, reduce the radiating effect of protection box 1 inside, the inner wall fixedly connected with insulation cover 2 of protection box 1 simultaneously, further improve the inside heat preservation effect of protection box 1, and sealed lid 8 also sets up to bilayer structure and inside and sets up to the vacuum, the inner wall fixedly connected with heat preservation pad 9 of sealed lid 8, the heat preservation effect after the sealed of the 1 inner wall of protection box that further improves.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation. The use of the phrase "comprising one of the elements does not exclude the presence of other like elements in the process, method, article, or apparatus that comprises the element.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.

Claims (8)

1. The utility model provides a protection device is deposited to mesenchymal stem cell freezing, includes protection box (1), storage tube (5), solenoid valve (7), refrigeration compressor (10) and heater (13), its characterized in that: the utility model discloses a protection box, including storage tube (5), storage tube (5) and anchor clamps two (4), the surface mounting of storage tube (5) has seal cover (6) to be used for sealing up storage tube (5) inner wall, storage tube (5) are fixed inside protection box (1) through anchor clamps (3) and anchor clamps two (4) centre gripping, the surface of protection box (1) is installed sealed lid (8) through the screw thread and is used for keeping warm to protection box (1) internal seal, the fixed surface of sealed lid (8) is connected with compressor (10) and is used for refrigerating, install on compressor (10) refrigeration pipe (11) and run through in the storage tube (5) of inserting protection box (1) internal fixation.
2. The mesenchymal stem cell cryopreservation protection device of claim 1, wherein: the first clamp (3) comprises a first sleeve (31), a first connecting spring (32), a first telescopic rod (33) and a first clamping plate (34), the first sleeve (31) is fixedly connected to the inner wall of the protective box body (1), the first telescopic rod (33) is inserted into the first sleeve (31), and the first clamping plate (34) is fixedly connected to the surface of the first telescopic rod (33);
the second clamp (4) comprises a second sleeve (41), a second connecting spring (42), a second telescopic rod (43) and a second clamping plate (44), the second sleeve (41) is fixedly connected to the inner wall of the protective box body (1), the second telescopic rod (43) is inserted into the second sleeve (41), and the second clamping plate (44) is fixedly connected to the surface of the second telescopic rod (43);
the first clamping plate (34) and the second clamping plate (44) are both arranged in a V-shaped structure, an opening is formed in the middle of the first clamping plate (34), the size of the opening is matched with that of the second clamping plate (44), and the second clamping plate (44) is located at the same horizontal height of the opening formed in the middle of the first clamping plate (34).
3. The mesenchymal stem cell cryopreservation protection device of claim 2, wherein: the surfaces of the first telescopic rod (33) and the first clamping plate (34) are fixedly connected with a first protection pad (35) and a second protection pad (45) respectively.
4. The mesenchymal stem cell cryopreservation protection device of claim 2, wherein: the surface of sleeve one (31) and sleeve two (41) all is provided with the spout, the surface of telescopic link one (33) and telescopic link two (43) is fixedly connected with gag lever post one (36) and gag lever post two (46) respectively, gag lever post one (36) and gag lever post two (46) insert respectively locate in the spout of sleeve one (31) and sleeve two (41) surface setting.
5. The mesenchymal stem cell cryopreservation protection device of claim 4, wherein: a first connecting spring (32) is fixedly connected inside the first sleeve (31), one end of the first connecting spring (32) is fixedly connected to the inner wall of the first sleeve (31), and the other end of the first connecting spring (32) is fixedly connected to the surface of the first telescopic rod (33);
the inner portion of the second sleeve (41) is fixedly connected with a second connecting spring (42), one end of the second connecting spring (42) is fixedly connected to the inner wall of the second sleeve (41), and the other end of the second connecting spring (42) is fixedly connected to the surface of the second telescopic rod (43).
6. The mesenchymal stem cell cryopreservation protection device of claim 1, wherein: the bottom fixedly connected with solenoid valve (7) of holding tube (5), the bottom surface central point of protection box (1) puts fixedly connected with heating cabinet (12), and the surface of heating cabinet (12) is provided with circular opening and circular open-ended outside fixedly connected with blotter (15), catch tray (14) are installed through the screw thread to the bottom surface of heating cabinet (12), and opening below fixedly connected with baffle (16) that heating cabinet (12) surface set up simultaneously, heating cabinet (12) internally mounted has heater (13).
7. The mesenchymal stem cell cryopreservation protection device of claim 1, wherein: the bottom end surface of the protection box body (1) is fixedly connected with supporting legs (17).
8. The mesenchymal stem cell cryopreservation protection device of claim 1, wherein: the wall shell of protection box (1) sets up to bilayer structure and inside and sets up to the vacuum, the inner wall fixedly connected with insulation cover (2) of protection box (1), the wall shell of sealed lid (8) sets up to bilayer structure and inside and sets up to the vacuum, the inner wall fixedly connected with heat preservation pad (9) of sealed lid (8).
CN202122502235.9U 2021-10-18 2021-10-18 Mesenchymal stem cell cryopreservation protection device Active CN215602868U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202122502235.9U CN215602868U (en) 2021-10-18 2021-10-18 Mesenchymal stem cell cryopreservation protection device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202122502235.9U CN215602868U (en) 2021-10-18 2021-10-18 Mesenchymal stem cell cryopreservation protection device

Publications (1)

Publication Number Publication Date
CN215602868U true CN215602868U (en) 2022-01-25

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CN202122502235.9U Active CN215602868U (en) 2021-10-18 2021-10-18 Mesenchymal stem cell cryopreservation protection device

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