CN219109860U - Full-development coating bracket - Google Patents

Full-development coating bracket Download PDF

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Publication number
CN219109860U
CN219109860U CN202222326627.9U CN202222326627U CN219109860U CN 219109860 U CN219109860 U CN 219109860U CN 202222326627 U CN202222326627 U CN 202222326627U CN 219109860 U CN219109860 U CN 219109860U
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groove
development
section
alloy
outer wide
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CN202222326627.9U
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田立剑
王英平
苏宏东
张汝翔
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Shandong Weixin Medical Equipment Co ltd
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Shandong Weixin Medical Equipment Co ltd
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

The utility model discloses a full-development coating bracket, which comprises a bracket base body, wherein the bracket base body comprises a plurality of bracket wave rods, development alloy and a drug coating, grooves penetrating through the inner surface and the outer surface are formed in the bracket wave rods, the grooves are axially arranged at intervals along the bracket base body, the development alloy is fixedly inserted into the grooves, the height of the development alloy is smaller than the depth of the grooves, the outer surface of the development alloy is matched with the grooves to form an outer drug carrying groove with an outward opening, the inner surface is matched with the grooves to form an inner drug carrying groove with an inward opening, and the drug coating is coated in the outer drug carrying groove, the inner drug carrying groove and the surface of the bracket base body.

Description

Full-development coating bracket
Technical Field
The utility model relates to the technical field of medical instruments, in particular to a full-development coating bracket.
Background
Vascular arterial stenosis is a current high mortality and high disability disease, and vascular stents are widely used to treat such vascular diseases, the principle of which is that the vascular stent reaches a lesion through a delivery system and then expands through the stent, thereby reconstructing a blood vessel, thereby treating the vascular stenosis. In the operation process, a doctor needs to accurately position and release the stent by means of the development performance of the vascular stent so as to ensure that the vascular stent can be accurately implanted into a lesion position, and after the operation, whether the stent is shifted or not needs to be confirmed by regular inspection, and the development performance of the stent plays a vital role in both the operation process and the operation.
In the prior art, developing marks are arranged at the near end and the far end of the stent, only partial development is performed, and integral development cannot be performed, so that the developing performance is limited, and if the process is unstable, a developing tube or developing material can be possibly separated, the developing material is separated, and the positioning and the postoperative inspection of the stent in operation are greatly affected.
In the prior art, a fully developed intravascular stent also appears, and through retrieval, CN2018219814912 discloses a developing mechanism convenient to fix and a intravascular stent thereof, and the developing mechanism comprises a supporting framework and a developing mechanism, wherein the supporting framework comprises a plurality of annular waveform supporting rods, the developing mechanism comprises developing pieces made of developing materials, the developing pieces can be stably fixed on any positions of the supporting framework, and the developing pieces are developing cylinders sleeved on the annular waveform supporting rods or developing wires wound on the annular waveform supporting rods or are attached to the surfaces of the annular waveform supporting rods.
The structure has the following defects: the developing piece is a developing tube sleeved on the supporting rod, a developing wire wound on the supporting rod or stuck on the supporting rod, so that the diameter of the bracket is necessarily increased, and a lesion part is difficult to reach in a long blood vessel with intracranial tortuosity; secondly, the developing part adopts a developing cylinder and a developing wire winding mode, so that the developing part is not easy to assemble on the bracket, and the manufacturing and processing cost and time are increased; thirdly, the developing wire is stuck on the surface of the supporting rod, and the stent easily falls off and flows into blood in the blood vessel delivery process, so that the life and health of a patient are affected.
Disclosure of Invention
The utility model aims to solve the defects of the prior art and provide the full-development coating stent which has good development effect, smooth delivery in tortuous vessels, low drug loss rate of stent delivery, large drug loading rate and long release period.
The technical scheme adopted for solving the technical problems is as follows:
the utility model provides a full development coating support, includes the support base member, the support base member includes a plurality of support ripples pole, its characterized in that: the drug-loading device is characterized by further comprising a developing alloy and a drug coating, wherein grooves penetrating through the inner surface and the outer surface are formed in the support wave rod, the grooves are axially arranged at intervals along the support base body, the developing alloy is fixedly inserted into the grooves, the height of the developing alloy is smaller than the depth of the grooves, the outer surface of the developing alloy is matched with the grooves to form an outer drug-loading groove with an outward opening, the inner surface of the developing alloy is matched with the grooves to form an inner drug-loading groove with an inward opening, and the drug coating is coated on the surfaces of the outer drug-loading groove, the inner drug-loading groove and the support base body;
through set up the recess on the support ripples pole, insert developing alloy in the recess to guarantee that a plurality of position of support base member length direction homoenergetic is developed, development performance is high, and developing alloy's setting can not influence the external diameter of support ripples pole and support base member simultaneously, guarantees the smooth and easy delivery of support in the blood vessel, and the setting of recess also can not influence the self-expansibility of support, and developing alloy has formed outer medicine carrying groove and interior medicine carrying groove with the recess cooperation, in order to increase support medicine carrying quantity, reduces the loss of support delivery in-process medicine, and the medicine release cycle is long.
The grooves are arranged to be of an outer wide and inner narrow structure, the left side wall of each groove is provided with a groove left inclined surface which is inclined from outside to inside to the inside of each groove, the right side wall of each groove is provided with a groove right inclined surface which is inclined from outside to inside to the inside of each groove, the shapes of the developing alloy are matched with those of the grooves, the grooves and the developing alloy are arranged to be of the outer wide and inner narrow structure, the developing alloy can be prevented from falling off from the inner side of the support, entering into blood vessels is prevented, and the inclined surfaces are arranged to play a guiding role at the same time, so that smooth installation of the developing alloy is ensured.
The groove comprises a groove outer wide section and a groove inner narrow section, wherein the groove outer wide section is communicated with the groove inner narrow section, the groove outer wide section is close to the outer surface of a bracket wave rod, the left side of the groove outer wide section is provided with a groove left inclined surface, the right side of the groove outer wide section is provided with a groove right inclined surface, the cross section of the groove outer wide section is in an inverted trapezoid shape, and the cross section of the groove inner narrow section is in a rectangle shape;
the development alloy comprises a development outer wide section and a development inner narrow section, the development outer wide section is connected with the development inner narrow section, the development outer wide section is close to the outer surface of the support wave rod, the left side of the development outer wide section is provided with a development left inclined plane which is inclined from outside to inside, the right side of the development outer wide section is provided with a development right inclined plane which is inclined from outside to inside, the section of the development outer wide section is in an inverted trapezoid matched with the outer wide section of the groove, and the section of the development inner narrow section is in a rectangle matched with the inner narrow section of the groove;
the structure can ensure that the developing alloy is convenient to assemble, and after the stent expands to support the vascular wall, the developing alloy cannot flow into blood from the inner side of the stent matrix, and meanwhile, the size of the inner medicine carrying groove is relatively large, so that the medicine carrying amount is increased.
The grooves are in a long strip shape arranged along the length direction of the support wave rod, so that the full developability of the support matrix is further ensured.
The grooves are arranged at intervals along the circumferential direction of the bracket base body, so that all angles of the bracket can be developed, and the development performance of the bracket is further ensured.
The developing alloy is in interference fit with the groove and is fixed by gluing or welding, so that the firmness of the developing alloy is further ensured, and the developing alloy is ensured not to fall off in a blood vessel.
The stent matrix is made of memory alloy capable of realizing self expansion, and the developing alloy is made of platinum alloy, gold alloy and the like.
The drug coating is coated on the outer surface of the stent matrix and in the external drug carrying groove, the cell proliferation inhibition drug is coated on the inner surface of the stent matrix and in the internal drug carrying groove, the cell proliferation inhibition drug can reduce the intimal transitional hyperplasia forming stenosis after the stent is implanted into the blood vessel, and the drug for preventing thrombosis can reduce the acute-phase thrombosis after the stent is implanted into the blood vessel.
The beneficial effects of the utility model are as follows: through set up the recess on the support ripples pole, insert developing alloy in the recess to guarantee that a plurality of position of support base member length direction homoenergetic is developed, development performance is high, and developing alloy's setting can not influence the external diameter of support ripples pole and support base member simultaneously, guarantees the smooth and easy delivery of support in the blood vessel, and the setting of recess also can not influence the self-expansibility of support, and developing alloy has formed outer medicine carrying groove and interior medicine carrying groove with the recess cooperation, in order to increase support medicine carrying quantity, reduces the loss of support delivery in-process medicine, and the medicine release cycle is long.
Drawings
Fig. 1 is a schematic diagram of the overall structure of the present utility model.
Fig. 2 is an enlarged schematic view at a in fig. 1.
Fig. 3 is a schematic diagram of a structure of a groove formed in a bracket according to the present utility model.
Fig. 4 is an enlarged schematic view at B in fig. 3.
FIG. 5 is a schematic diagram of a groove structure according to the present utility model.
Fig. 6 is a schematic view of the groove cut-off structure of fig. 5.
Fig. 7 is a side view of fig. 6.
FIG. 8 is a schematic diagram of the configuration of the groove and developing alloy of the present utility model.
FIG. 9 is a schematic view of a cut-off structure of the recess and developed alloy of FIG. 8.
Fig. 10 is a side view of fig. 9.
Reference numerals: the device comprises a bracket wave rod-1, a groove-101, a groove left inclined plane-1011, a groove right inclined plane-1012, a developing alloy-2, a developing outer wide section-203, a developing left inclined plane-2031, a developing right inclined plane-2032, a developing lower narrow section-204, an outer medicine carrying groove-301 and an inner medicine carrying groove-302.
Detailed Description
The utility model is described below with reference to the drawings and examples.
As shown in fig. 1-10, a full-development coating bracket comprises a bracket base body, wherein the bracket base body comprises a plurality of bracket wave rods 1, the structure of the bracket base body is related to how adjacent bracket wave rods are connected to be the prior art, details are not repeated here, the embodiment is also provided with development alloy 2 and a drug coating, grooves 101 penetrating through the inner surface and the outer surface are arranged on the bracket wave rods 1, the grooves 101 are axially arranged at intervals along the bracket base body, the development alloy 2 is fixedly inserted in the grooves 101, the height of the development alloy 2 is smaller than the depth of the grooves 101, the outer surface of the development alloy 2 is matched with the grooves 101 to form an outer drug carrying groove 301 with an outward opening, the inner surface is matched with the grooves to form an inner drug carrying groove 302 with an inward opening, and the drug coating is coated in the outer drug carrying groove 301, the inner drug carrying groove 302 and the surfaces of the bracket base body;
through set up recess 101 on support ripples pole 1, insert developing alloy 2 in recess 101 to guarantee that a plurality of position of support base member length direction homoenergetic is developed, development performance is high, and the setting of developing alloy 2 can not influence the external diameter of support ripples pole 1 and support base member simultaneously, guarantees that the support can smooth and easy delivery in the blood vessel, and recess 101's setting also can not influence the self-expansibility of support, and developing alloy 2 has formed outer medicine carrying groove 301 and interior medicine carrying groove 302 with recess 101 cooperatees, in order to increase support medicine carrying quantity, reduces the loss of support delivery in-process medicine, and the medicine release cycle is long.
In the prior art, the difficulty of processing the inner medicine carrying groove on the inner surface of the bracket matrix is great, which is a pain point in the industry, while the structure of the bracket in the embodiment is simple to process, so that full development can be realized, and the problem of great processing difficulty of the inner medicine carrying groove can be solved.
The groove 101 is arranged to be of an outer wide and inner narrow structure, a groove left inclined surface 1011 inclining from outside to inside towards the inside of the groove is arranged on the left side wall of the groove 101, a groove right inclined surface 1012 inclining from outside to inside towards the inside of the groove is arranged on the right side wall, the shape of the developing alloy 2 is matched with that of the groove 101, the developing alloy 2 and the groove 101 are arranged to be of an outer wide and inner narrow structure, the developing alloy 2 can be prevented from falling off from the inner side of the bracket, entering into a blood vessel is prevented, and the inclined surface is arranged to play a guiding role simultaneously, so that smooth installation of the developing alloy 2 is ensured.
The groove 101 comprises a groove outer wide section and a groove inner narrow section, the groove outer wide section is communicated with the groove inner narrow section, the groove outer wide section is close to the outer surface of the bracket wave rod 1, the left side of the groove outer wide section is provided with a groove left inclined plane 1011, the right side of the groove outer wide section is provided with a groove right inclined plane 1012, the cross section of the groove outer wide section is in an inverted trapezoid shape, and the cross section of the groove inner narrow section is in a rectangle shape;
the developing alloy 2 comprises a developing outer wide section 203 and a developing inner narrow section 204, the developing outer wide section 203 is connected with the developing inner narrow section 204, the developing outer wide section 203 is close to the outer surface of the bracket wave rod 1, a developing left inclined surface 2031 inclining from outside to inside is arranged on the left side of the developing outer wide section 203, a developing right inclined surface 2032 inclining from outside to inside is arranged on the right side of the developing outer wide section 203, the cross section of the developing outer wide section 203 is an inverted trapezoid matched with the outer wide section of the groove, and the cross section of the developing inner narrow section 204 is a rectangle matched with the inner narrow section of the groove;
the structure arrangement can ensure that the developing alloy 2 is convenient to assemble, and after the stent expands to support the vessel wall, the developing alloy cannot flow into blood from the inner side of the stent matrix, and meanwhile, the size of the inner medicine carrying groove 302 is relatively large, so that the medicine carrying amount is increased.
The shape of the groove 101 is a long strip shape arranged along the length direction of the bracket wave rod 1, so that the full developability of the bracket matrix is further ensured.
The grooves 101 are arranged at intervals along the circumferential direction of the support base body, so that all angles of the axial circumferential direction of the support can be developed, and the development performance of the support is further guaranteed.
In this embodiment, the developing alloy 2 is in interference fit with the groove 101 and is fixed by gluing or welding, so that the firmness of the developing alloy is further ensured, and the developing alloy is ensured not to fall off in a blood vessel.
In the embodiment, the stent matrix is made of memory alloy, self-expansion can be realized, the developing alloy can adopt platinum alloy, gold alloy and the like, and the drug coating coated on the outer surface of the stent matrix and in the external drug carrying groove is cell proliferation inhibiting drug, so that the formation of stenosis caused by transitional hyperplasia of an inner membrane after the stent is implanted into a blood vessel can be reduced, the drug coating on the inner surface of the stent matrix and in the internal drug carrying groove is drug for preventing thrombosis, and the formation of thrombus in the acute stage after the stent is implanted into the blood vessel is reduced.
In this example, rapamycin is used as the cytostatic drug, heparin is used as the antithrombotic drug, and the choice of the drug coating composition is not limited to the one that can be selected according to the actual use.
In this embodiment, fig. 5 to 10 are only schematic views, and the support wave rod is set to be straight so as to more clearly and intuitively show the matching relationship between the grooves and the developing alloy, but the actual support wave rod is not limited to be straight, but may be curved.
The processing and assembling method of the bracket matrix groove in the embodiment comprises the following steps:
step S1: fixing the memory alloy pipe, and performing laser cutting according to the designed lines to form grooves 101;
step S2: processing the developing alloy 2 matched with the shape of the groove by a mode of die extrusion or laser cutting;
step S3: the developing alloy 2 is inserted into the groove 101 in an interference manner from outside to inside, and is further fixed in a gluing or welding mode, etc., the outer surface of the developing alloy 2 is matched with the groove 101 to form an outer medicine carrying groove 301, and the inner surface is matched with the groove to form an inner medicine carrying groove 302.
The coating method of the drug coating in this embodiment is as follows:
step S1: selecting a shaft-shaped mold with the outer diameter matched with the inner diameter of the bracket matrix, inserting the bracket matrix on the mold, attaching the inner surface of the bracket matrix to the mold at the moment, coating a drug coating with a cell proliferation inhibiting drug on the outer surface of the bracket matrix by adopting a dip-coating or spray-coating mode, coating the drug coating on the parts, which are not provided with grooves, of the outer drug carrying groove and the outer surface of the bracket at the moment, and extracting the mold;
step S2: after the external surface drug coating is coated, the coating is solidified and formed by ultraviolet rays;
step S3: selecting a sleeve-shaped mould with the inner diameter matched with the outer diameter of the stent matrix, inserting the stent matrix into the mould, matching the outer surface of the stent matrix with the inner wall of the mould at the moment, coating a medicine coating of an antithrombotic medicine on the inner surface of the stent matrix by adopting a dip-coating or spray-coating mode, coating medicine coatings on the parts, which are not provided with grooves, of the inner medicine carrying groove and the inner surface of the stent at the moment, and taking the stent matrix out of the mould;
step S4: the inner surface drug coating is formed by ultraviolet curing after being coated.

Claims (7)

1. The utility model provides a full development coating support, includes the support base member, the support base member includes a plurality of support ripples pole, its characterized in that: still be equipped with development alloy and medicine coating, be equipped with the recess that runs through inside and outside surface on the support ripples pole, the recess sets up along support base member axial interval, the fixed development alloy that inserts in the recess, the high degree of depth that is less than the recess of development alloy, the surface of development alloy cooperatees with the recess and forms the outside medicine carrying groove of opening outwards, and the interior surface cooperatees with the recess and forms the inside medicine carrying groove of opening inwards, the outside medicine carrying inslot, the interior medicine carrying inslot and the surface of support base member all are coated with the medicine coating.
2. A full-development coated stent as defined in claim 1, wherein: the development alloy is characterized in that the groove is of an outer wide and inner narrow structure, a left inclined surface of the groove which inclines from outside to inside is arranged on the left side wall of the groove, a right inclined surface of the groove which inclines from outside to inside is arranged on the right side wall of the groove, and the shape of the development alloy is matched with that of the groove.
3. A full-development coated stent as defined in claim 2, wherein: the groove comprises a groove outer wide section and a groove inner narrow section, the groove outer wide section is communicated with the groove inner narrow section, the groove outer wide section is close to the outer surface of the support wave rod, a groove left inclined surface is arranged on the left side of the groove outer wide section, a groove right inclined surface is arranged on the right side of the groove outer wide section, the cross section of the groove outer wide section is of an inverted trapezoid shape, and the cross section of the groove inner narrow section is of a rectangle shape;
the development alloy comprises a development outer wide section and a development inner narrow section, the development outer wide section is connected with the development inner narrow section, the development outer wide section is close to the outer surface of the support wave rod, the left side of the development outer wide section is provided with a development left inclined plane inclined inwards from outside to inside, the right side of the development outer wide section is provided with a development right inclined plane inclined inwards from outside to inside, the section shape of the development outer wide section is an inverted trapezoid matched with the groove outer wide section, and the section shape of the development inner narrow section is a rectangle matched with the groove inner narrow section.
4. A full-development coated stent according to claim 1 or 2 or 3, wherein: the shape of the groove is a long strip shape arranged along the length direction of the support wave rod.
5. A full-development coated stent as defined in claim 4 wherein: the grooves are arranged at intervals along the circumferential direction of the bracket base body.
6. A full-development coated stent according to claim 1 or 2 or 3 or 5, characterized in that: the developing alloy is in interference fit with the groove and is fixed by gluing or welding.
7. A full-development coated stent according to claim 1 or 2 or 3 or 5, characterized in that: the drug coating is coated on the outer surface of the stent matrix and in the outer drug carrying groove, adopts cell proliferation inhibition drugs, and is coated on the inner surface of the stent matrix and in the inner drug carrying groove, adopts drugs for preventing thrombosis.
CN202222326627.9U 2022-09-01 2022-09-01 Full-development coating bracket Active CN219109860U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202222326627.9U CN219109860U (en) 2022-09-01 2022-09-01 Full-development coating bracket

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202222326627.9U CN219109860U (en) 2022-09-01 2022-09-01 Full-development coating bracket

Publications (1)

Publication Number Publication Date
CN219109860U true CN219109860U (en) 2023-06-02

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ID=86522434

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202222326627.9U Active CN219109860U (en) 2022-09-01 2022-09-01 Full-development coating bracket

Country Status (1)

Country Link
CN (1) CN219109860U (en)

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