CN219084854U

CN219084854U - Liquid phase flow cell

Info

Publication number: CN219084854U
Application number: CN202223504061.0U
Authority: CN
Inventors: 郭耀武; 赵富荣; 刘晓; 张欣; 曹育联
Original assignee: Konomi Suzhou Medical Device Technology Co ltd
Current assignee: Konomi Suzhou Medical Device Technology Co ltd
Priority date: 2022-12-26
Filing date: 2022-12-26
Publication date: 2023-05-26
Anticipated expiration: 2032-12-26

Abstract

The application relates to the technical field of liquid phase detection, especially, relate to a liquid phase flow cell, it includes two optic fibre, feed liquor pipe, drain pipe and mount pad, be provided with two adapter on the mount pad, be connected with the quartz capsule between two adapters, two optic fibre wear to establish inside the quartz capsule, feed liquor pipe and drain pipe all communicate with the quartz capsule, be provided with a plurality of support columns on the adapter, two optic fibre, feed liquor pipe and drain pipe are close to the one end of adapter all and are provided with the heat-conducting ring, the heat-conducting ring is connected with the support column. The optical fiber axis alignment accuracy is improved, so that the accuracy of the detection result of the detector is improved.

Description

Liquid phase flow cell

Technical Field

The application relates to the technical field of liquid phase detection, in particular to a liquid phase flow cell.

Background

In the case of analyzing components contained in a liquid sample, a widely used device is a liquid chromatograph. Liquid chromatography is an instrument that uses the difference in partition ratio of a mixture between two liquids, liquid-solid or immiscible, to separate the mixture first and then analyze the mixture with a detector.

The detector is used for converting the change of the composition and content of the sample in the effluent of the column into a signal for detection, the common detector is an ultraviolet absorption detector, a fluorescence detector, a differential refraction detector and the like, the flow cell is a key component of a liquid phase detector and is used for storing the sample to be detected, and the method is used for measuring the different absorption degree of the sample passing through the flow cell to light with specific wavelength so as to detect the property and concentration of the sample.

In the liquid phase flow cell recorded in the related art, two optical fibers are penetrated in the liquid phase flow cell, the two optical fibers are communicated through a quartz tube, two liquid inlet tubes and two liquid outlet tubes for flowing a sample to be tested are respectively communicated to two ends of the quartz tube, in the testing process, the axes of the two optical fibers need to be aligned, namely the axes of the two optical fibers are mutually coincident so that light can be transmitted along a straight line, and when the sample to be tested flows, the sample to be tested is convenient to carry out chromatographic detection on the sample to be tested. However, the diameter of the optical fiber used in the liquid phase flow cell is smaller, and the diameter of the optical fiber used in the liquid phase flow cell is only 0.45 mm, so that the difficulty of aligning the optical fiber axis is high, when the alignment of the optical fiber axis has deviation, when a sample to be tested flows through the quartz tube, the passing optical fiber cannot directly irradiate the sample to be tested, and the accuracy of the detection result of the detector can be reduced.

Disclosure of Invention

In order to improve the accuracy of the alignment of the optical fiber axis and the accuracy of the detection result of the detector, the application provides a liquid phase flow cell.

The application provides a liquid phase flow cell adopts following technical scheme:

the utility model provides a liquid phase flow cell, includes two optic fibre, feed liquor pipe, drain pipe and mount pad, be provided with two adapter on the mount pad, two be connected with the quartz capsule between the adapter, two optic fibre wears to establish inside the quartz capsule, the feed liquor pipe with the drain pipe all with the quartz capsule intercommunication, be provided with a plurality of support columns on the adapter, two optic fibre the feed liquor pipe and the drain pipe is close to the one end of adapter all is provided with the heat-conducting ring, the heat-conducting ring with the support column is connected.

Through adopting above-mentioned technical scheme, whole device is placed under high temperature environment, and the support column on the adapter melts, and is fixed to the heat-conducting ring, also can realize simultaneously fixing and sealing optic fibre, stainless steel pipe and quartz capsule, like this, just improved the accuracy that the optic fibre axis aligned, and then improved the accuracy of detector testing result.

Optionally, there is the clearance that can supply the sample to be measured to flow through between the optic fibre with the quartz capsule inner wall, the feed liquor pipe with the drain pipe is close to the one end of adapter all communicates there is first connector, the both ends of quartz capsule all communicate there is the second connector, two first connector respectively with the second connector that is close to communicates.

Through adopting above-mentioned technical scheme, the sample that awaits measuring can flow in from the feed liquor pipe, flows through the quartz capsule, flows out from the drain pipe at last.

Optionally, a heat conducting ring retainer is arranged on the mounting seat, and a notch into which the heat conducting ring is embedded is formed in the heat conducting ring retainer.

Through adopting above-mentioned technical scheme, offer the recess that can supply the heat-conducting ring card to go into on the heat-conducting ring holder, can prevent like this that the heat-conducting ring from taking place the position offset when hot melt to cause optic fibre and quartz capsule not coaxial.

Optionally, the mounting seat is formed with a rib, and the adapter is provided with a limit groove in which the rib is embedded.

Through adopting above-mentioned technical scheme, realize the chucking fixed to the adapter.

Optionally, a through hole is formed in the adapter, and the through hole is communicated with the limit groove.

Through adopting above-mentioned technical scheme, be convenient for glue injection through the through-hole to fix adapter and bead.

Optionally, the upper and lower structures of the adapter are symmetrical.

Through adopting above-mentioned technical scheme, after the adapter upset, the adapter can normal use, convenient to use and replacement.

Optionally, two fixing seats are arranged on the mounting seat, and the axes of the two fixing seats are coincident with the axis of the optical fiber.

By adopting the technical scheme, the optical fiber is further reinforced, so that the position of the optical fiber cannot appear in the detection process.

Optionally, two positioning seats are arranged on the mounting seat, and the liquid inlet pipe and the liquid outlet pipe are respectively arranged on the positioning seats in a penetrating manner.

By adopting the technical scheme, the liquid inlet pipe and the liquid outlet pipe are fixed.

Optionally, a protective shell is sleeved outside the mounting seat.

Through adopting above-mentioned technical scheme, can play thermal-insulated effect, also can play shock attenuation buffering's effect in use and transportation to mount pad and internals to the inside play guard action.

In summary, the present application includes at least one of the following beneficial technical effects:

1. the optical fiber detector is provided with the mounting seat, the adapter and the heat conducting ring, the two adapters are arranged on the mounting seat, the two optical fibers are respectively arranged on the two adapters in a penetrating mode and are communicated through the quartz tube, the heat conducting ring is arranged at one end of each optical fiber, each stainless steel tube, which is close to the adapter, the heat conducting ring is connected with the mounting seat, and the adapter is made of a peek material, so that the whole detector is placed in a high-temperature environment, a supporting column on the adapter is melted, the heat conducting ring is fixed, and meanwhile, the fixing and sealing of the optical fibers, the stainless steel tubes and the quartz tube can be realized, so that the accuracy of the alignment of optical fiber axes is improved, and the accuracy of the detection result of the detector is improved;

2. the heat conducting ring retainer is arranged, when the adapter is melted, the heat conducting ring is easy to drive to move together, and because the heat conducting ring is sleeved on the optical fiber, the movement of the heat conducting ring is easy to enable the optical fiber to deviate, and the heat conducting ring retainer is provided with the groove into which the heat conducting ring can be clamped, so that the position deviation of the heat conducting ring during hot melting can be prevented, and the optical fiber and the quartz tube are not coaxial;

3. the application is provided with the protective housing, and the protective housing adopts the foaming cotton material, and the protective housing cover is established in whole mount pad outside, can play thermal-insulated effect, also can play shock attenuation buffering's effect in use and transportation to mount pad and internals to the inside play guard action.

Drawings

FIG. 1 is a schematic diagram of the structure of a liquid phase flow cell in an embodiment of the present application;

FIG. 2 is a top view of a liquid phase flow cell in an embodiment of the present application;

fig. 3 is a cross-sectional view of a swivel in an embodiment of the application.

Reference numerals illustrate: 1. a mounting base; 2. a rib; 3. an optical fiber; 4. a liquid inlet pipe; 5. a liquid outlet pipe; 6. a heat conducting ring; 7. a thermally conductive ring holder; 8. a support column; 9. an adapter; 901. a limit groove; 902. a through hole; 10. a quartz tube; 11. a positioning seat; 12. a protective shell; 13. a fixing seat; 14. a first connector; 15. and a second connector.

Detailed Description

The present application is described in further detail below in conjunction with figures 1-3.

The embodiment of the application discloses liquid phase flow cell, refer to fig. 1 and 2, this liquid phase flow cell includes two optic fibre 3, feed liquor pipe 4, drain pipe 5 and quartz capsule 10, and two optic fibre 3 are all worn to establish in quartz capsule 10, and feed liquor pipe 4 and drain pipe 5 all communicate with quartz capsule 10, and the sample that awaits measuring can flow in from feed liquor pipe 4, flows through quartz capsule 10, flows out from drain pipe 5 at last. The liquid phase flow cell still includes mount pad 1, is provided with two adapter 9 that are used for connecting two optic fibre 3 and quartz capsule 10 on the mount pad 1, is provided with a plurality of support columns 8 on every adapter 9, in this embodiment, has set up three support column 8 on every adapter 9, and two optic fibre 3, feed liquor pipe 4 and drain pipe 5 are close to the one end of two adapter 9 all and are provided with heat-conducting ring 6, and every heat-conducting ring 6 all overlaps and establish on support column 8.

Through setting up adapter 9, improved the accuracy that two optic fibre 3 pass through quartz capsule 10 and align, place under the high temperature environment when whole device, heat-conducting ring 6 can give support column 8 with heat transfer, support column 8 is molten state and cladding at two optic fibre 3 under the high temperature condition, quartz capsule 10, drain pipe 5 and drain pipe 5 surface, after accomplishing the cooling, the liquid of molten state becomes solid, realize the fixed to two optic fibre 3, quartz capsule 10, drain pipe 5 and drain pipe 5 for at the testing process, the axis of two optic fibre 3 is in the state of alignment all the time, with the direct irradiation of assurance light, and then improve the accuracy of detector testing result.

Specifically, referring to fig. 2 and 3, each optical fiber 3 is inserted into the adaptor 9 adjacent to the optical fiber 3, two ends of the quartz tube 10 are respectively inserted into the two adaptors 9, a gap through which a sample to be tested can flow exists between the optical fiber 3 and the inner wall of the quartz tube 10, the liquid inlet tube 4 and the liquid outlet tube 5 are both connected with the first connector 14, two ends of the quartz tube 10 are both connected with the second connector 15, the optical fiber 3 is inserted on the second connector 15, and the two first connectors 14 are respectively communicated with the second connector 15 adjacent to the first connector.

In this embodiment, since the quartz tube 10 is resistant to high temperature and corrosion, the quartz tube 10 is used for connecting the two optical fibers 3. The liquid inlet pipe 4, the liquid outlet pipe 5, the first connector 14 and the second connector 15 are all made of stainless steel pipes. The adapter 9 is made of polyether-ether-ketone (peek), which can resist high temperature, organic reagent and stable performance. The mounting seat 1 is made of zirconia, alumina and ceramic materials, which are high in thermal stability, and cannot be obviously deformed due to high temperature, and the alignment of the optical fiber 3 cannot be influenced, and in the embodiment, the material of the mounting seat 1 is not particularly limited. The heat conducting ring 6 is made of aluminum material, and the aluminum material is corrosion-resistant and good in heat conductivity.

Of course, other existing materials with similar properties to the above materials may be selected according to actual situations, and the selected materials may meet the detection requirement, and in this embodiment, specific description will not be given.

Referring to fig. 2, a rib 2 parallel to the axis of the optical fiber 3 is machined on the fixing seat 13, and a limit groove 901 into which the rib 2 can be embedded is formed on the adapter 9, so as to realize clamping and fixing of the adapter 9. The upper surface of the adapter 9 is also provided with a through hole 902, and the through hole 902 is communicated with the limit groove 901, so that glue can be conveniently injected through the through hole 902 to fix the adapter 9 with the convex rib 2. Meanwhile, the adapter 9 is of an up-down symmetrical structure, and when the adapter 9 is turned over, the adapter 9 can be normally used, so that the adapter is convenient to use and replace.

After the support column 8 becomes the liquid of molten state, drive heat conducting ring 6 together to remove easily, because heat conducting ring 6 cover is established on optic fibre 3, like this, heat conducting ring 6 removes and makes optic fibre 3 take place the skew easily to influence the accuracy of detection data. In order to restrict the heat conducting ring 6, be fixed with heat conducting ring holder 7 on the mount pad 1, heat conducting ring holder 7 is the U type, and the opening direction sets up the direction towards bead 2, and the breach that can supply heat conducting ring 6 embedding is seted up to heat conducting ring holder 7, through setting up the breach, and heat conducting ring 6 can realize the chucking fixedly, and the liquid of molten state can cladding on the breach moreover, further consolidates heat conducting ring 6 after the cooling to improve the fixed stability of optic fibre 3. Since the material performance of the heat conducting ring holder 7 needs to be stable, in this embodiment, the material of the heat conducting ring holder 7 is stainless steel, and of course, other existing materials meeting the requirements can be selected.

Referring to fig. 2, in order to further strengthen the optical fiber 3 to ensure that the optical fiber 3 does not appear in position during the detection process, two fixing seats 13 are fixed on the mounting base 1, the axis of the fixing seat 13 coincides with the axis of the optical fiber 3, and the two optical fibers 3 are respectively connected to the two fixing seats 13 to achieve fixation.

Because the sample to be tested is liquid, certain impact can be generated by liquid flow, and the liquid outlet pipe 5 and the liquid inlet pipe 4 can be offset, so that the accuracy of detection data is reduced. In order to fix the liquid inlet pipe 4 and the liquid outlet pipe 5, two positioning seats 11 are fixed on the mounting seat 1, and the liquid inlet pipe 4 and the liquid outlet pipe 5 are respectively arranged on the corresponding positioning seats 11 in a penetrating way, so that the liquid inlet pipe 4 and the liquid outlet pipe 5 are fixed. The material of the positioning seat 11 can resist high temperature, and stainless steel, polyether ether ketone and the like can be adopted, and in the embodiment, the material of the positioning seat 11 is not particularly limited.

The protective shell 12 is sleeved outside the mounting seat 1, the material of the protective shell 12 is foamed cotton (EVA), the protective shell 12 can play a role in heat insulation, and also can play a role in shock absorption and buffering in the using and transporting processes, so that the mounting seat 1 and internal parts inside are protected.

In this embodiment, the fixing of each part is performed by using adhesive or hot-melt connection, and a specific fixing manner may be selected according to practical situations.

The implementation principle of the liquid phase flow cell in the embodiment of the application is as follows: firstly, the two adapters 9, the two heat conducting ring retainers 7 and the two positioning seats 11 are fixed, the heat conducting ring 6 is sleeved on the two optical fibers 3, the liquid inlet pipe 4 and the liquid outlet pipe 5, then the quartz tube 10 is arranged between the two adapters 9 in a penetrating mode, the two optical fibers 3, the liquid inlet pipe 4 and the liquid outlet pipe 5 are communicated with the quartz tube 10, and then the heat conducting ring 6 and the heat conducting ring 6 retainers are fixed. And then the whole device is placed into a high-temperature melting machine, so that the support column 8 on the adapter 9 is melted and coated on the surface of a nearby pipe fitting, and the fixing is realized after cooling. The light source is turned on, light irradiates along the two optical fibers 3 directly, and the sample to be detected flows out along the pipeline to finish detection. In this way, in the detection process, the axes of the two optical fibers 3 can be always in an aligned state, so as to ensure the direct irradiation of light, and further improve the accuracy of the detection result of the detector.

The foregoing are all preferred embodiments of the present application, and are not intended to limit the scope of the present application in any way, therefore: all equivalent changes in structure, shape and principle of this application should be covered in the protection scope of this application.

Claims

1. A liquid phase flow cell, characterized in that: including two optic fibre (3), feed liquor pipe (4), drain pipe (5) and mount pad (1), be provided with two adapter (9) on mount pad (1), two be connected with quartz capsule (10) between adapter (9), two optic fibre (3) wear to establish inside quartz capsule (10), feed liquor pipe (4) with drain pipe (5) all with quartz capsule (10) intercommunication, be provided with a plurality of support columns (8) on adapter (9), two optic fibre (3) feed liquor pipe (4) and drain pipe (5) are close to the one end of adapter (9) all is provided with heat-conducting ring (6), heat-conducting ring (6) with support column (8) are connected.

2. The liquid-phase flow cell according to claim 1, wherein: the optical fiber (3) and the inner wall of the quartz tube (10) are provided with a gap through which a sample to be tested can flow, one end, close to the adapter (9), of the liquid inlet tube (4) and the liquid outlet tube (5) is communicated with a first connector (14), two ends of the quartz tube (10) are communicated with a second connector (15), and the two first connectors (14) are respectively communicated with the second connectors (15) which are close to each other.

3. The liquid-phase flow cell according to claim 1, wherein: the mounting seat (1) is provided with a heat conducting ring retainer (7), and a notch for embedding the heat conducting ring (6) is formed in the heat conducting ring retainer (7).

4. The liquid-phase flow cell according to claim 1, wherein: the mounting seat (1) is provided with a convex rib (2), and the adapter (9) is provided with a limit groove (901) for embedding the convex rib (2).

5. The liquid-phase flow cell according to claim 4, wherein: the adapter (9) is provided with a through hole (902), and the through hole (902) is communicated with the limit groove (901).

6. The liquid-phase flow cell according to claim 4, wherein: the upper and lower structures of the adapter (9) are symmetrical.

7. The liquid-phase flow cell according to claim 1, wherein: two fixing seats (13) are arranged on the mounting seat (1), and the axes of the two fixing seats (13) are coincident with the axis of the optical fiber (3).

8. The liquid-phase flow cell according to claim 1, wherein: two positioning seats (11) are arranged on the mounting seat (1), and the liquid inlet pipe (4) and the liquid outlet pipe (5) are respectively arranged on the positioning seats (11) in a penetrating mode.

9. The liquid-phase flow cell according to claim 1, wherein: a protective shell (12) is sleeved outside the mounting seat (1).