CN219072196U

CN219072196U - Liposome extrusion instrument

Info

Publication number: CN219072196U
Application number: CN202222460552.3U
Authority: CN
Inventors: 瞿鼎
Original assignee: Moti Ningbo Biotechnology Co ltd
Current assignee: Moti Ningbo Biotechnology Co ltd
Priority date: 2022-09-15
Filing date: 2022-09-15
Publication date: 2023-05-26
Anticipated expiration: 2032-09-15

Abstract

The utility model relates to the technical field of liposome preparation and discloses a liposome extruder which comprises a bottom plate, wherein servo motors are fixedly connected to the middle parts of two sides of the upper end surface of the bottom plate, two first mounting blocks are fixedly connected to the middle parts of two sides of the upper end surface of the bottom plate, threaded sleeves are rotatably connected to the inner parts of the first mounting blocks, threaded rods are connected to the inner sides of the threaded sleeves in a threaded manner, the threaded rods are connected with injection barrels through injection rods, one ends of the injection barrels are arranged at one end of a connecting pipe, and the other ends of the two connecting pipes are respectively and fixedly connected to the middle parts of two sides of a U-shaped mounting block. According to the utility model, by starting the servo motor at one side, the liposome extruding instrument can automatically extrude, so that the problem that a worker needs to manually extrude a liposome, which consumes much time, is solved, the workload effect of the worker is effectively reduced, the filter screen in the extruding module can be quickly replaced and inspected by pulling the pull block, and the working efficiency of the liposome extruding instrument is greatly improved.

Description

Liposome extrusion instrument

Technical Field

The utility model relates to the technical field of liposome preparation, in particular to a liposome extruder.

Background

The liposome is prepared from lecithin, ceramide and the like, has a bilayer structure identical to a skin cell membrane structure, has an excellent moisturizing effect on skin, and particularly has excellent moisturizing effect on skin, and is coated with moisturizing substances such as hyaluronic acid, polyglucoside and the like.

At present, the traditional liposome extrusion mode is often manually carried out liposome extrusion work by manpower, a large amount of time is required to be consumed, the workload of staff is increased, and secondly, the traditional liposome extrusion mode at present generally controls medicament products to be repeatedly filtered through a filter screen through a piston pipeline, liposome extrusion in the medicament products is realized after multiple times of filtration, but the filter screen used in the liposome extrusion mode is often inconvenient to quickly replace and check, the filter screen blocking phenomenon is easy to occur after multiple times of use, and the overall efficiency of liposome extrusion is easy to be reduced.

Disclosure of Invention

The utility model aims to solve the defects in the prior art and provides a liposome extruder.

In order to achieve the above purpose, the present utility model adopts the following technical scheme: the utility model provides a liposome extrusion appearance, includes the bottom plate, the equal fixedly connected with servo motor in bottom plate upper end surface both sides middle part, the equal fixedly connected with pivot of servo motor one side drive end, the equal fixedly connected with gear one of pivot other end, the equal fixedly connected with two installation pieces in bottom plate upper end surface both sides middle part are first, two the inside threaded sleeve that rotates of installation piece is connected with, the equal fixedly connected with gear two in threaded sleeve outside middle part, threaded sleeve inboard all threaded connection has the threaded rod, threaded rod one end all runs through installation piece two and fixedly connected with injection pole, the equal sliding connection in injection pole other end outside is inboard at the injection tube, injection tube one end all sets up in connecting pipe one end, two the connecting pipe other end is fixedly connected with in U type installation piece both sides middle part respectively, the inside equal sliding connection of both sides lateral wall has two T type spouts in the U type installation piece, four the inside all is provided with the cavity in installation piece three both sides respectively of T type slider, the inside all is provided with the cavity in U type installation piece both sides upper end, the cavity is inboard, one all sliding connection has the equal clamping block.

As a further description of the above technical solution:

and the other end of the threaded rod is fixedly connected with a first limiting block.

As a further description of the above technical solution:

the middle part of the three upper ends of the mounting block is fixedly connected with a handle.

As a further description of the above technical solution:

and a filter screen is arranged in the third installation block.

As a further description of the above technical solution:

and one end of the clamping block is set to be an inclined plane, and the other end of the clamping block is fixedly connected with a pulling block.

As a further description of the above technical solution:

the upper end and the lower end of the side wall of one side in the cavity are fixedly connected with reset springs, and the other ends of the two reset springs are respectively and fixedly connected with the upper end and the lower end of one side of the sliding block.

As a further description of the above technical solution:

the middle parts of the upper sides of the three ends of the mounting block are respectively provided with a clamping groove, and one ends of clamping blocks are respectively clamped on the inner sides of the clamping grooves.

As a further description of the above technical solution:

the threaded rod is characterized in that a second limiting block is fixedly connected to the upper end of one side of the threaded rod, the outer side of the second limiting block is slidably connected to the inner side of a first sliding groove, the first sliding groove is arranged inside the upper end of a second mounting block, and the two mounting blocks are fixedly connected to the middle parts of two sides of the surface of the upper end of the bottom plate respectively.

The utility model has the following beneficial effects:

1. according to the utility model, the servo motor at one side is started, the rotating shaft can control the rotation of the first gear, the first gear is meshed with the second gear, the servo motor can control the rotation of the second gear, the threaded sleeve can move the threaded rod, the second gear is fixedly connected to the outer side of the threaded sleeve, the servo motor can control the movement of the threaded rod, the threaded rod pushes the injection rod, the liposome extruder can automatically extrude, the problem that a worker needs to manually extrude for a long time is solved, and the workload effect of the worker is effectively reduced.

2. According to the utility model, the clamping block is driven to move by pulling the pulling block, so that one end of the clamping block is not clamped with the clamping groove, the T-shaped sliding groove and the T-shaped sliding block are further utilized to hold the handle, the mounting block III is taken out, and when the liposome extruding device is mounted, the T-shaped sliding block is inserted into the T-shaped sliding groove, and as one end of the clamping block is set to be an inclined plane, the mounting block III ejects the clamping block, and when the clamping block reaches the clamping groove position, the reset spring pushes the sliding block I to move, so that the sliding block I drives the clamping block to move, and then one end of the clamping block is clamped with the clamping groove, the mounting of the mounting block III is completed, the filter screen in the extruding module can be quickly replaced and inspected, and the working efficiency of the liposome extruding device is greatly improved.

Drawings

Fig. 1 is a schematic perspective view of a liposome extruder according to the present utility model;

fig. 2 is a three-dimensional schematic diagram of a mounting block of a liposome extrusion apparatus according to the present utility model;

fig. 3 is a three-dimensional schematic diagram of a U-shaped mounting block of a liposome extruder according to the present utility model;

FIG. 4 is a front cross-sectional view of a chamber of a liposome extrusion apparatus according to the present utility model;

fig. 5 is a schematic perspective view of a threaded rod of a liposome extruder according to the present utility model;

fig. 6 is a front cross-sectional view of a chute of a liposome extrusion apparatus according to the present utility model.

Legend description:

1. a bottom plate; 2. a first mounting block; 3. a servo motor; 4. a first gear; 5. a second mounting block; 6. a grip; 7. a clamping block; 8. pulling blocks; 9. a connecting pipe; 10. a second gear; 11. a threaded sleeve; 12. a first limiting block; 13. a chamber; 14. a threaded rod; 15. an injection rod; 16. a syringe; 17. a third mounting block; 18. a return spring; 19. a U-shaped mounting block; 20. a rotating shaft; 21. a T-shaped slider; 22. a filter screen; 23. a clamping groove; 24. a second limiting block; 25. a first chute; 26. a T-shaped chute; 27. and a first sliding block.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

In the description of the present utility model, it should be noted that, directions or positional relationships indicated by terms such as "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., are based on directions or positional relationships shown in the drawings, are merely for convenience of description and simplification of description, and do not indicate or imply that the apparatus or element to be referred to must have a specific direction, be constructed and operated in the specific direction, and thus should not be construed as limiting the present utility model; the terms "first," "second," "third," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying relative importance, and furthermore, unless explicitly specified and limited otherwise, the terms "mounted," "connected," "coupled," and the like are to be construed broadly, and may be fixedly coupled, detachably coupled, or integrally coupled, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present utility model will be understood in specific cases by those of ordinary skill in the art.

Referring to fig. 1-6, one embodiment provided by the present utility model is: a liposome extruder comprises a bottom plate 1, wherein the middle parts of two sides of the upper end surface of the bottom plate 1 are fixedly connected with a servo motor 3, one side driving end of the servo motor 3 is fixedly connected with a rotating shaft 20, the other end of the rotating shaft 20 is fixedly connected with a first gear 4, the middle parts of two sides of the upper end surface of the bottom plate 1 are fixedly connected with two first mounting blocks 2, the inside of the two first mounting blocks 2 is rotationally connected with a threaded sleeve 11, the middle parts of the outer sides of the threaded sleeve 11 are fixedly connected with a second gear 10, the servo motor 3 is conveniently started, the rotating shaft 20 can control the rotation of the first gear 4, the first gear 4 is meshed with the second gear 10, the servo motor 3 can control the rotation of the second gear 10, the inner side of the threaded sleeve 11 is uniformly connected with a threaded rod 14, one end of the threaded rod 14 penetrates through the second mounting block 5 and is fixedly connected with an injection rod 15, the outer side of the other end of the injection rod 15 is slidably connected with the inner side of the injection cylinder 16, the threaded rod 14 can be conveniently moved by the rotation of the threaded sleeve 11, the outer side of the threaded sleeve 11 is fixedly connected with the gear II 10, thereby the movement of the threaded rod 14 can be controlled by the servo motor 3, the threaded rod 14 pushes the injection rod 15, one end of the injection cylinder 16 is arranged at one end of the connecting pipe 9, the solution can conveniently enter the extrusion module through the connecting pipe 9, the other ends of the two connecting pipes 9 are fixedly connected with the middle parts of two sides of the U-shaped mounting block 19 respectively, two T-shaped sliding grooves 26 are arranged in the inner side walls of the two sides of the U-shaped mounting block 19 respectively, T-shaped sliding blocks 21 are slidably connected with the inner sides of the T-shaped sliding grooves 26 respectively, chambers 13 are respectively arranged in the upper ends of the two sides of the U-shaped mounting block 19 respectively, the inner sides of the chambers 13 are slidably connected with a first sliding block 27, the inner sides of the first sliding block 27 are fixedly connected with a clamping block 7, conveniently, the pulling block 8 is pulled to drive the clamping block 7 to move, so that one end of the clamping block 7 is not clamped with the clamping groove 23, and then the handle 6 is held by the T-shaped sliding groove 26 and the T-shaped sliding block 21 to take out the mounting block III 17.

The other end of the threaded rod 14 is fixedly connected with a first limiting block 12, the threaded rod 14 is limited by the first limiting block 12 respectively, the threaded rod 14 can not rotate out of the threaded sleeve 11, the middle part of the upper end of the third 17 of the installation block is fixedly connected with a handle 6, when the third 17 of the installation block is taken out, the third 17 of the installation block is pulled out by the handle 6 conveniently, the filter screen 22 is arranged in the third 17 of the installation block, the liposome is filtered conveniently by the filter screen 22 so as to facilitate liposome extrusion, one end of the clamping block 7 is set to be an inclined plane, the other end of the clamping block 7 is fixedly connected with the pulling block 8 conveniently, one end of the clamping block 7 is not clamped with the clamping groove 23 by pulling the pulling block 8, the third 17 of the installation block can be taken out, the upper end and the lower end of the side wall of one side in the cavity 13 are fixedly connected with reset springs 18, the other ends of the two reset springs 18 are respectively fixedly connected with the upper end and the lower end of one side of the sliding block 27, the first slider 27 is pushed by the reset spring 18 conveniently, and then the clamping block 7 can move, thereby the clamping groove 23 is clamped, the middle parts of the upper sides of the two ends of the third mounting block 17 are respectively provided with the clamping groove 23, one end of the clamping block 7 is clamped at the inner side of the clamping groove 23, the third mounting block 17 is fixed by the clamping block 7 clamped at the inner side of the clamping groove 23, the third mounting block 17 can not shake when the liposome extrusion work is carried out, the second limiting block 24 is fixedly connected with the upper end of one side of the threaded rod 14, the outer side of the second limiting block 24 is slidably connected with the inner side of the first sliding groove 25, the first sliding groove 25 is arranged in the upper end of the second mounting block 5, the two mounting blocks 5 are fixedly connected with the middle parts of the two sides of the upper end surface of the bottom plate 1 respectively, the threaded rod 14 is limited by the second limiting block 24, and the threaded rod 14 can only move left and right along with the threaded sleeve 11 when the threaded rod rotates.

Working principle: when the device is used, through starting one side servo motor 3, because the rotation of gear one 4 can be controlled to pivot 20, and gear one 4 and gear two 10 meshing are connected, and then servo motor 3 can control the rotation of gear two 10, because the rotation of screw sleeve 11 can make threaded rod 14 remove, and screw sleeve 11 outside fixed connection gear two 10, thereby can control the removal of threaded rod 14 through servo motor 3, threaded rod 14 promotes injection pole 15, the liposome extruder can extrude the work voluntarily, avoided the staff to need manual extrusion to consume much time, effectively reduced staff's work load effect, through pulling pull piece 8, drive fixture block 7 and remove, make fixture block 7 one end do not block slot 23, and then utilize T type spout 26 and T type slider 21, take out installation piece three 17, during the installation, through inserting T type spout 26 with T type slider 21, because fixture block 7 one end sets up to the inclined plane, installation piece three 17 is ejecting fixture block 7, when fixture block 7 reaches the card slot 23 position, reset spring 18 promotes slider one 27, thereby the slider one 27 moves fixture block 7, install the 7 clamp block 7, install the quick change of clamp block 23, and then install the large-size filter screen 22 has been realized, the large-scale extrusion efficiency is realized, and the large-speed change efficiency of the filter screen is realized, and the large-scale extrusion efficiency is realized.

Finally, it should be noted that: the foregoing description is only illustrative of the preferred embodiments of the present utility model, and although the present utility model has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described, or equivalents may be substituted for elements thereof, and any modifications, equivalents, improvements or changes may be made without departing from the spirit and principles of the present utility model.

Claims

1. Liposome extrusion apparatus, comprising a base plate (1), characterized in that: the middle parts of two sides of the upper end surface of the bottom plate (1) are fixedly connected with a servo motor (3), one side driving end of the servo motor (3) is fixedly connected with a rotating shaft (20), the other end of the rotating shaft (20) is fixedly connected with a first gear (4), the middle parts of two sides of the upper end surface of the bottom plate (1) are fixedly connected with two first mounting blocks (2), the two first mounting blocks (2) are internally and rotatably connected with a threaded sleeve (11), the middle parts of the outer sides of the threaded sleeve (11) are fixedly connected with a second gear (10), the inner sides of the threaded sleeve (11) are fixedly connected with a threaded rod (14), one end of the threaded rod (14) penetrates through the second mounting block (5) and is fixedly connected with an injection rod (15), the outer side of the other end of the injection rod (15) is slidably connected with the inner side of the injection cylinder (16), one end of the injection cylinder (16) is arranged at one end of the connecting pipe (9), the other ends of the two connecting pipes (9) are fixedly connected with the middle parts of two sides of the U-shaped mounting block (19) respectively, two T-shaped sliding grooves (26) are formed in the inner side walls of the two sides of the U-shaped mounting block (19), T-shaped sliding blocks (21) are slidably connected with the inner side of the T-shaped sliding grooves (26), the four T-shaped sliding blocks (21) are arranged on the two sides of the third mounting block (17) respectively, the U-shaped mounting block is characterized in that cavities (13) are formed in the inner parts of the upper ends of the two sides of the U-shaped mounting block (19), the inner sides of the cavities (13) are connected with a first sliding block (27) in a sliding mode, and clamping blocks (7) are fixedly connected to the inner sides of the first sliding block (27).

2. A liposome extrusion apparatus according to claim 1, wherein: the other end of the threaded rod (14) is fixedly connected with a first limiting block (12).

3. A liposome extrusion apparatus according to claim 1, wherein: the middle part of the upper end of the third mounting block (17) is fixedly connected with a handle (6).

4. A liposome extrusion apparatus according to claim 1, wherein: a filter screen (22) is arranged in the third mounting block (17).

5. A liposome extrusion apparatus according to claim 1, wherein: one end of the clamping block (7) is provided with an inclined plane, and the other end of the clamping block (7) is fixedly connected with a pulling block (8).

6. A liposome extrusion apparatus according to claim 1, wherein: the upper end and the lower end of the side wall of one side in the cavity (13) are fixedly connected with reset springs (18), and the other ends of the two reset springs (18) are fixedly connected with the upper end and the lower end of one side of the first sliding block (27) respectively.

7. A liposome extrusion apparatus according to claim 1, wherein: the middle parts of the upper sides of the two ends of the mounting block III (17) are respectively provided with a clamping groove (23), and one end of the clamping block (7) is clamped on the inner sides of the clamping grooves (23).

8. A liposome extrusion apparatus according to claim 1, wherein: the upper end of one side of the threaded rod (14) is fixedly connected with a second limiting block (24), the outer side of the second limiting block (24) is slidably connected to the inner side of a first sliding groove (25), the first sliding groove (25) is arranged inside the upper end of a second installation block (5), and the two second installation blocks (5) are fixedly connected to the middle parts of two sides of the upper end surface of the bottom plate (1) respectively.