CN219016600U - Reagent strip reagent leakage and filling detection device - Google Patents

Reagent strip reagent leakage and filling detection device Download PDF

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Publication number
CN219016600U
CN219016600U CN202223104003.9U CN202223104003U CN219016600U CN 219016600 U CN219016600 U CN 219016600U CN 202223104003 U CN202223104003 U CN 202223104003U CN 219016600 U CN219016600 U CN 219016600U
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reagent
hole
liquid flow
liquid
leakage
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CN202223104003.9U
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Chinese (zh)
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许勇
刘东勇
刘晓勇
包德泉
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Chengdu Aixing Biotechnology Co ltd
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Chengdu Aixing Biotechnology Co ltd
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Abstract

The utility model provides a reagent strip and reagent leakage and filling detection device, which comprises a detection component, wherein the detection component is provided with a loading box body and a non-contact liquid flow induction component, the loading box body is provided with a first through hole which can correspond to a reagent hole of a reagent strip, the non-contact liquid flow induction component comprises a liquid flow induction piece and a control board, the control board is provided with a frequency synthesizer, the frequency synthesizer is provided with an extension line, the extension line is electrically connected with the liquid flow induction piece, the liquid flow induction piece is provided with a second through hole, a liquid injection pipe is suspended at a hole opening at one side of the second through hole, which is far away from the first through hole, an outflow opening of the liquid injection pipe, the first through hole and the second through hole are coaxially arranged, a detection circuit is arranged in the control board, and the detection circuit can judge whether reagent liquid flows through the second through hole according to an output signal of the frequency synthesizer. The utility model realizes the judgment of the leakage of the reagent liquid in the reagent hole by utilizing the sensed capacitance change condition without manual judgment, and has higher detection sensitivity and more reliable detection result.

Description

Reagent strip reagent leakage and filling detection device
Technical Field
The utility model belongs to the field of reagent filling device design, and particularly relates to a reagent strip reagent leakage detection device.
Background
In the liquid detection device commonly used in the prior art, an optical detection or weight detection mode is generally adopted to identify whether the reagent is leaked or not. However, the filling reagent amount of the reagent strips is extremely low, most of the reagent strips are concentrated below 100 microliters and the reagent strips rapidly move on a production line, so that the weight detection mode commonly used in the market cannot meet the required precision and efficiency requirements; since the filling reagent is sensitive to light, the optical detection method is not applicable. Based on this, at present, aiming at a reagent filling system of a reagent strip, whether the reagent strip is leaked or not usually adopts an artificial naked eye to observe whether liquid drops fall down (flow down filling), which is very labor-consuming and has poor reliability. Based on this, the present utility model has been proposed.
Disclosure of Invention
Therefore, the technical problem to be solved by the utility model is to provide a reagent strip reagent leakage detection device, so as to overcome the defects of labor consumption and poor reliability in a mode of manually observing whether liquid drops fall or not in a reagent strip reagent filling system in the prior art.
In order to solve the problems, the utility model provides a reagent strip reagent leakage and irrigation detection device, which comprises a detection assembly, wherein the detection assembly is provided with a loading box body and a non-contact liquid flow induction assembly, the loading box body is provided with a first through hole which can correspond to a reagent hole of a reagent strip, the non-contact liquid flow induction assembly comprises a liquid flow induction sheet and a control board, wherein the control board is provided with a frequency synthesizer which is provided with an extension line, the extension line is electrically connected with the liquid flow induction sheet, the liquid flow induction sheet is provided with a second through hole, a liquid injection pipe is suspended at a side orifice of the second through hole, which is away from the first through hole, an outflow port of the liquid injection pipe, the first through hole and the second through hole are coaxially arranged, and a detection circuit is arranged in the control board and can judge whether reagent liquid flows through the second through hole according to an output signal of the frequency synthesizer.
In some embodiments, the material of the loading cassette is an electromagnetic shielding material or the loading cassette has an electromagnetic shielding layer.
In some embodiments, the loading box body has a plurality of first through holes, the plurality of first through holes are arranged at intervals along a first direction, and each first through hole is respectively provided with the non-contact liquid flow sensing piece and the liquid filling pipe.
In some embodiments, the loading cassette has an electromagnetic shield between two adjacent flow sensing plates.
In some embodiments, the liquid flow sensing piece is ring-shaped with a notch, and at least part of the notch of the liquid flow sensing piece is located towards one side of the electromagnetic shielding part.
In some embodiments, an insulating sleeve is disposed at the orifice of the first through hole, the central through hole of the insulating sleeve is coaxial with the outflow port of the liquid injection pipe, and the annular liquid flow sensing piece is sleeved on the outer circumferential wall of the insulating sleeve.
In some embodiments, the arc length of the notch is s, and the circumference of the circular ring is L,1/2 < s/L.ltoreq.1/4.
In some embodiments, the reagent strip and reagent leakage and filling detection device further comprises an assembly bracket, the assembly bracket comprises a T-shaped beam, the T-shaped beam comprises a cross beam and a longitudinal beam, the detection assemblies are provided with two groups, and the two groups of detection assemblies are symmetrically assembled at two ends of the cross beam respectively relative to the longitudinal beam.
In some embodiments, the reagent strip and reagent leakage detection device further comprises a control box body, wherein the control box body is connected to the assembly bracket, and the control board is accommodated in the control box body; and/or the assembly rack can be driven to linearly reciprocate along a direction perpendicular to the length direction of the reagent strip.
In some embodiments, a liquid injection block is formed on one side of the loading box body away from the first through hole, and the liquid injection block can position one end of a liquid outlet of the liquid injection pipe; and/or the outer side wall of the control box body is connected with a pipeline fixing block, and the pipeline fixing block can fix the region of the liquid injection pipe away from the outflow port.
According to the reagent strip reagent leakage and filling detection device provided by the utility model, the non-contact liquid flow sensing assembly can realize the judgment of reagent liquid leakage and filling of the reagent hole by utilizing the capacitance change condition through non-contact detection of the reagent liquid flowing in the second through hole, the adverse effect on the reagent liquid caused by a non-optical detection mode is also more accurate than the detection result of a quality detection mode, meanwhile, the manual judgment is not needed, the detection sensitivity is higher, and the detection result is more reliable.
Drawings
FIG. 1 is a schematic perspective view of a reagent strip and reagent leakage detection device (including a reagent strip) according to an embodiment of the present utility model;
FIG. 2 is a schematic diagram showing an exploded structure of the reagent strip and reagent leakage detecting apparatus in FIG. 1;
FIG. 3 is a schematic diagram of a reagent strip and reagent leakage detection device according to another embodiment of the present utility model (including a reagent strip and a reagent strip holder);
FIG. 4 is a schematic perspective view of parts of a reagent strip and reagent leakage detecting apparatus according to another embodiment of the present utility model.
The reference numerals are expressed as:
1. loading the box body; 11. an electromagnetic shielding section; 12. injecting liquid blocks; 21. a flow sensing sheet; 22. a control board; 23. an insulating sleeve; 3. a liquid injection pipe; 41. t-shaped beam; 5. a control box body; 51. a pipeline fixing block; 100. a reagent strip; 101. a reagent well; 102. a reagent strip holder.
Detailed Description
Referring to fig. 1 to 4, according to an embodiment of the present utility model, a reagent strip reagent leakage detection device is provided, including a detection assembly, the detection assembly includes a loading box body 1 and a non-contact type liquid flow sensing assembly, the loading box body 1 has a first through hole corresponding to a reagent hole 101 of a reagent strip 100, the non-contact type liquid flow sensing assembly includes a liquid flow sensing plate 21 and a control plate 22, wherein the control plate 22 has a frequency synthesizer, the frequency synthesizer has an extension line, the extension line is electrically connected with the liquid flow sensing plate 21, the liquid flow sensing plate 21 corresponds to an orifice of the first through hole, a second through hole is configured on the liquid flow sensing plate 21, a liquid injection pipe 3 is suspended at an orifice of a side of the second through hole facing away from the first through hole, and a detection circuit is configured in the control plate 22, and the detection circuit can determine whether a reagent liquid flows through the second through hole according to an output signal of the frequency synthesizer.
In this technical scheme, when a liquid flow passes through the second through hole of the liquid flow sensing piece 21, the capacitance of the component and the extension line electrically connected with the component will change, so that the input voltage on the frequency synthesizer is changed, then the frequency synthesizer outputs a frequency to be compared with the standard frequency, when the two frequencies are the same, a pulse signal is output to the corresponding interface of the control board 22, and the detection circuit judges whether the reagent liquid flows through the second through hole according to the corresponding pulse signal, namely the output signal of the frequency synthesizer.
The non-contact liquid flow sensing assembly can realize judgment of reagent liquid leakage of the reagent hole 101 by utilizing capacitance change conditions through non-contact detection of whether the reagent liquid flows through the second through hole, and has no adverse effect on the reagent liquid caused by a detection mode, and the detection result is more accurate than that of a quality detection mode, meanwhile, manual judgment is not needed, the detection sensitivity is higher, and the detection result is more reliable.
It should be noted that, the foregoing non-contact liquid flow sensing assembly may be implemented by using a related detection component with a frequency synthesizer in the market, and its implementation principle is well known, and the present utility model is not intended to protect the same.
In order to prevent the interference of the external electromagnetic wave to the liquid flow sensing sheet 21 and also prevent the possible electromagnetic interference of the liquid flow sensing sheet 21 to the external components, the material of the loading box 1 is an electromagnetic shielding material, specifically, for example, the loading box 1 may be directly made of metal such as stainless steel, so that the loading box 1 has rigidity and structural strength as an assembly carrier, and in another embodiment, the electromagnetic shielding anti-interference effect may be achieved by providing an electromagnetic shielding layer on the outer side of the loading box 1.
In some embodiments, the loading box 1 has a plurality of first through holes, and the plurality of first through holes are arranged at intervals along the first direction, specifically, the number and the positions of the first through holes are matched with the reagent holes 101 of the reagent strips 100 under the first through holes, and each first through hole is respectively and correspondingly provided with a liquid flow sensing piece and a liquid injection tube 3, so that the filling of one reagent strip 100 can be completed at one time only at one position, and the filling efficiency is greatly improved.
At this time, in order to prevent mutual interference between the two adjacent liquid flow sensing pieces 21, the electromagnetic shielding portion 11 is further provided in the loading cassette 1, and the electromagnetic shielding portion 11 is located between the two adjacent liquid flow sensing pieces 21, so that electromagnetic interference between the two adjacent liquid flow sensing pieces 21 can be prevented.
In a preferred embodiment, as shown in fig. 4, the liquid flow sensing piece 21 is in a circular shape with a notch, and at least part of the notch of the liquid flow sensing piece 21 faces to one side of the electromagnetic shielding part 11, and the notch penetrates through two axial ends of the liquid flow sensing piece 21 to make the circular shape be a non-complete circular shape, so that the center-to-center distance between two adjacent liquid flow sensing pieces 21 is matched with the distance between two adjacent reagent holes 101 on the same reagent strip 100, and meanwhile, the electromagnetic shielding part 11 is provided with enough arrangement space, so that electromagnetic interference between two adjacent liquid flow sensing pieces 21 is effectively prevented, and the reliability and accuracy of a detection result are ensured.
In some embodiments, the arc length of the notch is s, the circumference of the circular ring is L,1/2 < s/L is less than or equal to 1/4, so that the liquid flow sensing piece 21 is formed into an arc-shaped semicircular ring structure with a major arc shape in appearance, in a preferred embodiment, the opening of the first through hole is provided with an insulating sleeve 23, the central through hole of the insulating sleeve 23 is coaxial with the outflow opening of the liquid injection tube 3, and the circular ring-shaped liquid flow sensing piece 21 is sleeved on the outer circumferential wall of the insulating sleeve 23, so that the liquid flow sensing piece 21 can be reliably connected to the outer circumferential wall of the insulating sleeve 23 in an interference fit manner by utilizing the major arc-shaped structure while the distance between each two adjacent liquid flow sensing pieces 21 is adapted to the distance between two adjacent reagent holes 101.
Referring to fig. 3, in another embodiment, the reagent strip reagent leakage and filling detection device further includes an assembly bracket (not labeled in the drawing), the assembly bracket includes a T-beam 41, the T-beam includes a cross beam and a longitudinal beam, the detection assemblies have two groups, and the two groups of detection assemblies are symmetrically assembled at two ends of the cross beam with respect to the longitudinal beam respectively, that is, the detection device has two detection assemblies, and can simultaneously fill each reagent hole 101 on two reagent strips 100 at one time, so as to further improve reagent filling efficiency. In a preferred embodiment, the assembly rack can be driven to reciprocate linearly in a direction perpendicular to the length direction (i.e., the first direction described above) of the reagent strip 100, which can change the relative positions of the various detection components with respect to the reagent strip 100 to effect reagent filling of different reagent strips 100.
Referring to fig. 3, the detection device for the reagent strip and the reagent leakage and filling further includes a control box 5, the control box 5 is connected to the assembly bracket, and the control board 22 is accommodated in the control box 5, specifically, the number of the control boxes 5 is also matched with the number of the detection components and is set in a one-to-one correspondence manner, and the control boards 22 corresponding to the liquid flow sensing pieces 21 in each detection component are all placed in the corresponding control box 5, so that the structure is more compact.
A liquid injection block 12 is formed on one side of the loading box body 1 far away from the first through hole, and the liquid injection block 12 can position one end of a liquid injection pipe 3 to position the tail end of each liquid injection pipe 3, so that the position between the liquid injection port and the first through hole is prevented from changing, and the reliable filling of reagent liquid is ensured; the pipeline fixing block 51 is connected to the outer side wall of the control box body 5, and the pipeline fixing block 51 can fix the area of the liquid injection pipe 3 away from the outflow port, so that the pipeline layout is optimized and stable, and the phenomena of pipeline winding and the like in the moving process of the device are prevented.
The reagent strip and reagent leakage detection device has the advantages of simple and compact overall structure and small occupied space.
It will be readily appreciated by those skilled in the art that the above advantageous ways can be freely combined and superimposed without conflict.
The foregoing description of the preferred embodiments of the utility model is not intended to be limiting, but rather is intended to cover all modifications, equivalents, and alternatives falling within the spirit and principles of the utility model. The foregoing is merely a preferred embodiment of the present utility model, and it should be noted that it will be apparent to those skilled in the art that modifications and variations can be made without departing from the technical principles of the present utility model, and these modifications and variations should also be regarded as the scope of the utility model.

Claims (10)

1. The utility model provides a detection device is irritated to reagent strip reagent hourglass, its characterized in that, including detection subassembly, detection subassembly has and loads box body (1), non-contact liquid flow response subassembly, it can have on box body (1) with the first through-hole that reagent hole (101) that reagent strip (100) had corresponds, non-contact liquid flow response subassembly includes liquid flow sensing piece (21), control panel (22), have the frequency synthesizer on control panel (22), the frequency synthesizer has the extension line, the extension line with liquid flow sensing piece (21) electricity is connected, be constructed with the second through-hole on liquid flow sensing piece (21), one side orifice department that the second through-hole deviates from first through-hole has notes liquid pipe (3), just the play mouth of notes liquid pipe (3) first through-hole and second through-hole three coaxial setting, be provided with detection circuitry in control panel (22), detection circuitry can judge according to the output signal of frequency synthesizer whether there is reagent liquid to flow through in the second through-hole.
2. The reagent strip reagent leakage detection device according to claim 1, wherein the material of the loading box body (1) is an electromagnetic shielding material or the loading box body (1) is provided with an electromagnetic shielding layer.
3. The reagent strip reagent leakage and filling detection device according to claim 2, wherein the loading box body (1) is provided with a plurality of first through holes, the plurality of first through holes are arranged at intervals along a first direction, and each first through hole is respectively provided with the non-contact liquid flow sensing assembly and the liquid filling pipe (3) in a corresponding manner.
4. The reagent strip and reagent leakage detection device according to claim 2, wherein the loading box body (1) is provided with an electromagnetic shielding part (11), and the electromagnetic shielding part (11) is positioned between two adjacent liquid flow induction sheets (21).
5. The reagent strip leakage detection device according to claim 4, wherein the liquid flow sensing piece (21) is in a ring shape with a notch, and at least part of the notch of the liquid flow sensing piece (21) is located towards the electromagnetic shielding part (11).
6. The reagent strip reagent leakage and filling detection device according to claim 5, wherein an insulating sleeve (23) is arranged at the orifice of the first through hole, the central through hole of the insulating sleeve (23) is coaxial with the outflow port of the liquid injection pipe (3), and the annular liquid flow sensing piece (21) is sleeved on the outer circumferential wall of the insulating sleeve (23).
7. The device for detecting reagent strip leakage according to claim 6, wherein the arc length of the notch is s, the circumference of the circular ring is L, and 1/2 < s/L is less than or equal to 1/4.
8. The device for detecting the leakage of reagent strips and reagent according to claim 1, further comprising an assembly bracket, wherein the assembly bracket comprises a T-beam (41), the T-beam comprises a cross beam and a longitudinal beam, the detection assemblies comprise two groups, and the two groups of detection assemblies are respectively and symmetrically assembled at two ends of the cross beam relative to the longitudinal beam.
9. The reagent strip and reagent leakage detection device according to claim 8, further comprising a control box (5), wherein the control box (5) is connected to the assembly bracket, and the control board (22) is accommodated in the control box (5); and/or the assembly rack can be driven to linearly reciprocate along a direction perpendicular to the length direction of the reagent strip (100).
10. The reagent strip reagent leakage detection device according to claim 9, wherein a liquid injection block (12) is formed on one side of the loading box body (1) far away from the first through hole, and the liquid injection block (12) can position one end of a liquid outlet of the liquid injection pipe (3); and/or the outer side wall of the control box body (5) is connected with a pipeline fixing block (51), and the pipeline fixing block (51) can fix the region of the liquid injection pipe (3) far away from the outflow port.
CN202223104003.9U 2022-11-22 2022-11-22 Reagent strip reagent leakage and filling detection device Active CN219016600U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202223104003.9U CN219016600U (en) 2022-11-22 2022-11-22 Reagent strip reagent leakage and filling detection device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202223104003.9U CN219016600U (en) 2022-11-22 2022-11-22 Reagent strip reagent leakage and filling detection device

Publications (1)

Publication Number Publication Date
CN219016600U true CN219016600U (en) 2023-05-12

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202223104003.9U Active CN219016600U (en) 2022-11-22 2022-11-22 Reagent strip reagent leakage and filling detection device

Country Status (1)

Country Link
CN (1) CN219016600U (en)

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