CN218981627U - Visual heat conduction device for isothermal amplification reaction - Google Patents

Visual heat conduction device for isothermal amplification reaction Download PDF

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Publication number
CN218981627U
CN218981627U CN202223238948.XU CN202223238948U CN218981627U CN 218981627 U CN218981627 U CN 218981627U CN 202223238948 U CN202223238948 U CN 202223238948U CN 218981627 U CN218981627 U CN 218981627U
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China
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heat conduction
metal body
conduction metal
heating slot
heating
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CN202223238948.XU
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Chinese (zh)
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钟秋
李进
贾喻惠
刘家振
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Chinese Peoples Liberation Army Army Specialized Medical Center
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Chinese Peoples Liberation Army Army Specialized Medical Center
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Abstract

The utility model provides a visual heat conduction device of constant temperature amplification reaction, includes the heat conduction metal body, the heat conduction metal body is the cuboid, be equipped with a plurality of downwardly extending's heating slot on the heat conduction metal body, the heating slot is used for inserting the detection box of constant temperature amplification reaction, the rectangle is personally submitted in the transversal of heating slot, be equipped with the air escape groove of following the axial extension of heating slot between two adjacent lateral walls of heating slot, be equipped with the bar observation hole with external intercommunication on the heating slot lateral wall, the axial extension of heating slot is followed to the bar observation hole for observe the colour change of detecting the interior colloidal gold test strip of box, the lower part is equipped with the temperature probe mounting hole in the heat conduction metal body, the heat conduction metal body bottom is equipped with the recess that is used for placing the heating plate. The visual heat conduction device for the isothermal amplification reaction effectively avoids aerosol pollution, simplifies detection steps, improves detection efficiency and reduces detection cost.

Description

Visual heat conduction device for isothermal amplification reaction
Technical Field
The utility model relates to the technical field of constant temperature heating, in particular to a visual heat conduction device for a constant temperature amplification reaction.
Background
The conventional constant-temperature metal bath heating aluminum block is only suitable for heating an EP tube in a common experiment, is easily limited by the space of an instrument when in use, and cannot meet the requirement of the height space for placing a colloidal gold test strip; in a isothermal amplification colloidal gold reaction experiment, an EP tube amplification product is taken out and diluted to easily cause aerosol pollution, and a colloidal gold test strip is easily influenced by different humidity, so that the influence deviation of a reaction result is larger, and experimental data is unstable.
With the rapid development of isothermal amplification technology, the existing isothermal metal bath heating aluminum block cannot meet the detection requirement of isothermal amplification colloidal gold test strips. Therefore, it is necessary to develop a visual heat conduction device for isothermal amplification reaction.
Disclosure of Invention
The utility model aims to provide a visual heat conduction device for isothermal amplification reaction, which solves the problems of complicated detection steps, low detection efficiency, high detection cost and the like of aerosol pollution during detection of a colloidal gold test strip for isothermal amplification reaction.
The purpose of the utility model is realized in the following way:
the utility model provides a visual heat conduction device of constant temperature amplification reaction, includes the heat conduction metal body, the heat conduction metal body is the cuboid, be equipped with a plurality of downwardly extending's heating slot on the heat conduction metal body, the heating slot is used for inserting the detection box of constant temperature amplification reaction, the rectangle is personally submitted in the transversal of heating slot, be equipped with the air escape groove of following the axial extension of heating slot between two adjacent lateral walls of heating slot, be equipped with the bar observation hole with external intercommunication on the heating slot lateral wall, the axial extension of heating slot is followed to the bar observation hole for observe the colour change of detecting the interior colloidal gold test strip of box, the lower part is equipped with the temperature probe mounting hole in the heat conduction metal body, the heat conduction metal body bottom is equipped with the recess that is used for placing the heating plate.
The top of the heat conduction metal body is provided with a flange, and the upper end face of the flange is flush with the upper end face of the heat conduction metal body.
Five heating slots are arranged side by side on the upper end face of the heat conduction metal body.
The cross section of the air leakage groove is arc-shaped.
The length T of the strip-shaped observation hole is smaller than the groove depth S of the heating slot and larger than one half of the groove depth S of the heating slot.
The heat conduction metal body is of an integrated structure.
The heat conduction metal body is an aluminum product.
The visual heat conduction device for the isothermal amplification reaction comprises a heat conduction metal body, wherein the heat conduction metal body is a cuboid, a plurality of heating slots extending downwards are arranged on the heat conduction metal body, the heating slots are used for being inserted into detection boxes for the isothermal amplification reaction, the cross section of each heating slot is rectangular, and air leakage grooves extending along the axial direction of each heating slot are arranged between two adjacent side walls of each heating slot, so that the right-angle detection boxes are inserted into the corresponding heating slots, and the detection boxes are clamped. The strip-shaped observation hole communicated with the outside is formed in the side wall of the heating slot, the strip-shaped observation hole extends along the axial direction of the heating slot and is used for observing the color change of the colloidal gold test strip in the detection box, so that the detection result of the colloidal gold test strip is observed under the condition that the detection box and the colloidal gold test strip are not taken out, the colloidal gold test strip is prevented from being polluted by aerosol in the air, and the accuracy of the detection result is ensured. The lower part is equipped with temperature probe mounting hole in the heat conduction metal body for install the temperature probe of constant temperature appearance, heat conduction metal body bottom is equipped with the recess that is used for placing the heating plate. Thereby make heat conduction metal body can be heated fast and even through the heating plate, improve the heating effect to the detection box, and be convenient for accurately carry out temperature regulation control, heat transfer effect better through the heating plate.
Compared with the prior art, the visual heat conduction device for the isothermal amplification reaction has the advantages of simple structure, easiness in realization, low production cost and convenience in outdoor carrying, can ensure that the humidity and the temperature of each colloidal gold test strip between each channel are kept consistent, observe the detection result through the strip observation holes, and effectively avoid aerosol pollution caused in the process of uncovering the test box without taking out the test box and the colloidal gold test strip, simplify the test steps, improve the detection efficiency and reduce the detection cost.
Drawings
FIG. 1 is a schematic diagram of the structure of the present utility model;
FIG. 2 is a front view of the present utility model;
FIG. 3 is a cross-sectional view taken along A-A of FIG. 2;
FIG. 4 is a bottom view of the present utility model;
fig. 5 is a top view of the present utility model.
Detailed Description
Referring to fig. 1 to 5, a visual heat conduction device for isothermal amplification reaction comprises a heat conduction metal body 1, wherein the heat conduction metal body 1 is a cuboid, a flange is arranged at the top of the heat conduction metal body 1, and the upper end face of the flange is flush with the upper end face of the heat conduction metal body 1. The heat conduction metal body 1 is provided with a plurality of heating slots 2 which extend downwards, the heating slots 2 are used for being inserted into a detection box for isothermal amplification reaction, the cross section of each heating slot 2 is rectangular, a gas leakage groove 6 which extends along the axial direction of the heating slot 2 is arranged between two adjacent side walls of each heating slot 2, and the cross section of each gas leakage groove 6 is arc-shaped. Thereby ensure that right angle detection box inserts and will not receive air resistance's influence in inserting to the heating slot to press from both sides tight detection box. The strip-shaped observation hole 3 communicated with the outside is formed in the side wall of the heating slot 2, the strip-shaped observation hole 3 extends along the axial direction of the heating slot 2 and is used for observing color change of the colloidal gold test strip in the detection box, and the length T of the strip-shaped observation hole 3 is smaller than the groove depth S of the heating slot 2 and larger than one half of the groove depth S of the heating slot 2. Therefore, the detection result of the colloidal gold test strip is observed under the condition that the detection box and the colloidal gold test strip are not taken out, the colloidal gold test strip is prevented from being polluted by aerosol in the air, and the accuracy of the detection result is ensured. The middle lower part of the heat conduction metal body 1 is provided with a temperature probe mounting hole 4 for mounting a temperature probe of a thermostat for isothermal amplification reaction, and the bottom of the heat conduction metal body 1 is provided with a groove 5 for placing a heating plate. Thereby make heat conduction metal body can be heated fast and even through the heating plate, improve the heating effect to the detection box, and be convenient for accurately carry out temperature regulation control, heat transfer effect better through the heating plate.
The heat conduction metal body 1 of the visual heat conduction device for isothermal amplification reaction of the embodiment is an aluminum product with an integrated structure, and five parallel heating slots 2 are arranged on the upper end surface of the heat conduction metal body 1. The height H of the heat conduction metal body 1 is 55+/-0.1 mm, the width W is 26+/-0.1 mm, the length L is 86+/-0.1 mm, and the thickness M of the flange is 2+/-0.1 mm. The groove depth S of the heating slot 2 is 50+/-0.1 mm, the width F is 20.10+/-0.05 mm, the length E is 9.10+/-0.05 mm, and the cross section of the air leakage groove 6 is an arc with the radius of 2.05 mm. The length T of the strip-shaped observation hole 3 is 27+/-0.1 mm, and the width K is 7+/-0.1 mm. The depth G of the groove 5 is 1.60+/-0.05 mm, the width D is 16+/-0.1 mm, and the length N is 71+/-0.1 mm. The aperture of the temperature probe mounting hole 4 is 5.10 plus or minus 0.05mm, and the hole depth is 20 plus or minus 0.1mm.
When the visual heat conduction device for isothermal amplification reaction works, a heat conduction metal body is arranged on a thermostat for isothermal amplification reaction, a detection box provided with a colloidal gold test strip is inserted into a heating slot for isothermal amplification reaction, a strip-shaped observation hole corresponds to the area of a detection line formed by the colloidal gold test strip, the detection box and the colloidal gold test strip do not need to be taken out when the detection result is observed, and a sight line can pass through the strip-shaped observation hole to observe the reaction of the colloidal gold test strip at any time so as to observe whether the colloidal gold test strip has a mauve strip. Thereby avoid taking out the colloidal gold test strip, lead to the colloidal gold test strip to be polluted by the aerosol in the air, and then guarantee that the testing result is accurate, improve detection efficiency, reduce detection cost.
The above description is only of the preferred embodiments of the present utility model and is not intended to limit the utility model, and those skilled in the art will appreciate that the modifications made to the utility model fall within the scope of the utility model without departing from the spirit of the utility model.

Claims (7)

1. The utility model provides a visual heat conduction device of constant temperature amplification reaction, includes heat conduction metal body (1), heat conduction metal body (1) are cuboid, its characterized in that: be equipped with a plurality of downwardly extending's heating slot (2) on heat conduction metal body (1), heating slot (2) are used for inserting the detection box of isothermal amplification reaction, the transversal rectangle that personally submits of heating slot (2), be equipped with between two adjacent lateral walls of heating slot (2) along the axial extension's of heating slot (2 air escape groove (6), be equipped with on heating slot (2) lateral wall with external intercommunication bar observation hole (3), the axial extension of heating slot (2) is followed in bar observation hole (3) for observe the colour change of detecting the interior colloidal gold test strip of box, heat conduction metal body (1) middle lower part is equipped with temperature probe mounting hole (4), heat conduction metal body (1) bottom is equipped with recess (5) that are used for placing the heating plate.
2. The visual heat transfer device for isothermal amplification reactions according to claim 1, wherein: the top of the heat conduction metal body (1) is provided with a flange, and the upper end face of the flange is flush with the upper end face of the heat conduction metal body (1).
3. The visual heat transfer device for isothermal amplification reactions according to claim 1, wherein: five parallel heating slots (2) are arranged on the upper end face of the heat conduction metal body (1).
4. The visual heat transfer device for isothermal amplification reactions according to claim 1, wherein: the cross section of the air leakage groove (6) is arc-shaped.
5. The visual heat transfer device for isothermal amplification reactions according to claim 1, wherein: the length T of the strip-shaped observation hole (3) is smaller than the groove depth S of the heating slot (2) and larger than one half of the groove depth S of the heating slot (2).
6. The visual heat transfer device for isothermal amplification reactions according to claim 1, wherein: the heat conduction metal body (1) is of an integrated structure.
7. The visual heat transfer device for isothermal amplification reactions according to claim 1, wherein: the heat conduction metal body (1) is an aluminum product.
CN202223238948.XU 2022-12-05 2022-12-05 Visual heat conduction device for isothermal amplification reaction Active CN218981627U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202223238948.XU CN218981627U (en) 2022-12-05 2022-12-05 Visual heat conduction device for isothermal amplification reaction

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202223238948.XU CN218981627U (en) 2022-12-05 2022-12-05 Visual heat conduction device for isothermal amplification reaction

Publications (1)

Publication Number Publication Date
CN218981627U true CN218981627U (en) 2023-05-09

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ID=86219468

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202223238948.XU Active CN218981627U (en) 2022-12-05 2022-12-05 Visual heat conduction device for isothermal amplification reaction

Country Status (1)

Country Link
CN (1) CN218981627U (en)

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