CN218969220U

CN218969220U - Two-connected bag for collecting and separating umbilical cord blood hematopoietic stem cells

Info

Publication number: CN218969220U
Application number: CN202223550121.2U
Authority: CN
Inventors: 冯娟; 崔南征
Original assignee: Zhongke Bosheng Bioengineering Co ltd
Current assignee: Zhongke Bosheng Bioengineering Co ltd
Priority date: 2022-12-23
Filing date: 2022-12-23
Publication date: 2023-05-05
Anticipated expiration: 2032-12-23

Abstract

The utility model relates to the technical field of collection and separation of umbilical cord blood hematopoietic stem cells, in particular to a two-way bag for collection and separation of umbilical cord blood hematopoietic stem cells, which is convenient for quantitatively introducing red blood cells in a left collection bag into a right collection bag by arranging the equipment, has simple operation, avoids remixing of the red blood cells, white blood cells and plasma in the left collection bag, and improves the collection and separation quality of the red blood cells; including right collection bag, hose, left collection bag and suction means, right collection bag and left collection bag pass through the hose intercommunication, be provided with suction means on the hose, suction means is including absorbing case, piston, pull rod, annular baffle, two sets of baffles and two sets of springs, two sets of baffles rotate and install on two sets of connecting pipes, right side baffle corresponds with annular baffle position, two sets of spring tops are connected with two sets of connecting pipe inner top, two sets of spring bottom are connected with two sets of baffle right-hand member, be provided with fixing device on the absorption case, fixing device is connected with the pull rod cooperation.

Description

Two-connected bag for collecting and separating umbilical cord blood hematopoietic stem cells

Technical Field

The utility model relates to the technical field of umbilical cord blood hematopoietic stem cell collection and separation, in particular to a two-way bag for collecting and separating umbilical cord blood hematopoietic stem cells.

Background

The umbilical cord blood is the blood remained in placenta and umbilical cord after the fetus is delivered and the umbilical cord is ligated and separated, contains hematopoietic stem cells which can reconstruct human hematopoietic and immune system, and can be used for hematopoietic stem cell transplantation for treating various diseases.

The existing two-way bag for collecting and separating umbilical cord blood hematopoietic stem cells is like patent CN201820133902.6, and comprises a collecting bag for storing an anticoagulant and a transferring bag for storing plasma and red blood cells, wherein a sampling and sampling port is formed in the upper portion of the transferring bag, a collecting bag sampling port is formed in the upper portion of the collecting bag, the upper portion of the transferring bag is communicated with the collecting bag through a first conduit, the bottom of the transferring bag is communicated with the bottom of the collecting bag through a second conduit, a third conduit is further arranged on the upper portion of the collecting bag, a needle communicated with the third conduit is fixedly connected to the lower end of the third conduit, a branch pipe is further communicated with the side portion of the third conduit, a cell filter screen is fixedly arranged in the middle of the branch pipe, a control valve for controlling the flow rate of liquid is arranged on the first conduit and the second conduit, and a flow stopping clamp is arranged on the third conduit and the branch pipe.

However, the patent has the defects that most of plasma is removed by the second positive centrifugation of the collecting bag, the control valve is opened to enable the plasma to slowly flow into the transferring bag, and then the control valve is closed to remove the plasma. The method is that the collecting bag is put into the plasma clamp for fixing the collecting bag, the red blood cells in the collecting bag are clamped and extruded by the plasma clamp, the operation is troublesome, the control is inconvenient, the red blood cells, the white blood cells and the plasma in the collecting bag are easy to mix again, or the excessive white blood cells are led out, and the collecting and separating quality is influenced.

Disclosure of Invention

In order to solve the technical problems, the utility model provides the two-way bag which is convenient for quantitatively introducing the red blood cells in the left collecting bag into the right collecting bag, has simple operation, avoids the re-mixing of the red blood cells, the white blood cells and the plasma in the left collecting bag, and improves the collecting and separating quality of the two-way bag.

The utility model discloses a two-joint bag for collecting and separating umbilical cord blood hematopoietic stem cells, which comprises a right collecting bag, a hose, a left collecting bag and a suction device, wherein the right collecting bag and the left collecting bag are communicated through the hose, the suction device is arranged on the hose and comprises a suction box, a piston, a pull rod, an annular baffle, two groups of baffles and two groups of springs, the suction box is arranged in the middle of the hose, connecting pipes are respectively communicated with the lower parts of the left end and the right end of the suction box, the hose is communicated with the two groups of connecting pipes, the piston slides in the suction box, the top end of the piston is connected with the bottom end of the pull rod, the pull rod is connected with the top end of the suction box in a sliding manner, the annular baffle is arranged in the right connecting pipe, the two groups of baffles are rotatably arranged on the two groups of connecting pipes, the top ends of the two groups of springs are connected with the top ends of the two groups of the springs, and the suction box is provided with a fixing device which is in matched connection with the pull rod.

The utility model relates to a two-joint bag for collecting and separating umbilical cord blood hematopoietic stem cells, which comprises a fixing frame and a threaded rod, wherein the upper part of the right end of the pull rod is provided with a jack, the bottom end of the fixing frame is connected with the top end of a suction box, the threaded rod is in threaded connection with the fixing frame, and the threaded rod corresponds to the jack in position.

The utility model discloses a two-joint bag for collecting and separating umbilical cord blood hematopoietic stem cells, which also comprises two groups of sealing rings, wherein the two groups of sealing rings are respectively arranged at the left ends of two groups of baffles.

The utility model discloses a two-joint bag for collecting and separating umbilical cord blood hematopoietic stem cells, which also comprises two groups of telescopic pipes and two groups of telescopic rods, wherein the two groups of telescopic pipes and the two groups of telescopic rods are respectively positioned in two groups of springs, the top ends of the two groups of telescopic pipes are rotationally connected with the top ends in the two groups of connecting pipes, the bottom ends of the two groups of telescopic rods are rotationally connected with the right ends of two groups of baffle plates, and the two groups of telescopic rods slide in the two groups of telescopic pipes.

The utility model discloses a two-joint bag for collecting and separating umbilical cord blood hematopoietic stem cells, which also comprises a handle, wherein the handle is arranged at the top end of a pull rod.

The utility model relates to a two-joint bag for collecting and separating umbilical cord blood hematopoietic stem cells, wherein a finger groove is arranged on a handle.

The utility model relates to a two-joint bag for collecting and separating umbilical cord blood hematopoietic stem cells, wherein the left end of a threaded rod is provided with a guide angle.

The utility model relates to a two-joint bag for collecting and separating umbilical cord blood hematopoietic stem cells, which also comprises a rotating handle, wherein the rotating handle is arranged at the right end of a threaded rod.

Compared with the prior art, the utility model has the beneficial effects that: through pulling the pull rod, the pull rod then drives the piston and upwards slide in the suction box, red blood cells in the left collection bag then promote left baffle through the hose and open, left side spring then takes place elastic deformation, then red blood cells enter into the suction box inside, then red blood cells promote right baffle and open, right side spring then takes place elastic deformation, red blood cells then import to the right collection bag inside through right side connecting pipe and hose, after red blood cells import to the jack in, through promoting the pull rod, the piston then downwards slides in the suction box, afterwards fix the pull rod through fixing device, thereby make the piston seal two sets of connecting pipes, through setting up this equipment, be convenient for with the quantitative import of red blood cells in the left collection bag to the right collection bag inside, the operation is simpler, red blood cells in the left collection bag have been avoided, white blood cells and plasma mix once more, the quality of its collection separation has been improved.

Drawings

FIG. 1 is a schematic diagram of the structure of the present utility model;

FIG. 2 is an enlarged schematic view of the structure of FIG. 1A;

FIG. 3 is an enlarged schematic view of the structure of B in FIG. 2;

FIG. 4 is an enlarged schematic view of the structure of FIG. 2C;

the reference numerals in the drawings: 1. a right collection bag; 2. a hose; 3. a suction box; 4. a connecting pipe; 5. a piston; 6. a pull rod; 7. an annular baffle; 8. a baffle; 9. a spring; 10. a jack; 11. a fixing frame; 12. a threaded rod; 13. a seal ring; 14. a telescopic tube; 15. a telescopic rod; 16. a handle; 17. a finger groove; 18. conducting angle; 19. a rotating handle; 20. left collection bag.

Detailed Description

The following describes in further detail the embodiments of the present utility model with reference to the drawings and examples. The following examples are illustrative of the utility model and are not intended to limit the scope of the utility model.

As shown in fig. 1 to 4, the two-way bag for collecting and separating umbilical cord blood hematopoietic stem cells comprises a right collecting bag 1, a hose 2, a left collecting bag 20 and a suction device, wherein the right collecting bag 1 and the left collecting bag 20 are communicated through the hose 2, the suction device is arranged on the hose 2 and comprises a suction box 3, a piston 5, a pull rod 6, an annular baffle 7, two groups of baffles 8 and two groups of springs 9, the suction box 3 is arranged in the middle of the hose 2, connecting pipes 4 are respectively communicated with the lower parts of the left end and the right end of the suction box 3, the hose 2 is communicated with the two groups of connecting pipes 4, the piston 5 slides in the suction box 3, the top end of the piston 5 is connected with the bottom end of the pull rod 6, the pull rod 6 is connected with the top end of the suction box 3 in a sliding manner, the annular baffle 7 is arranged in the right connecting pipe 4, the two groups of baffles 8 are rotatably arranged on the two groups of connecting pipes 4, the top ends of the two groups of springs 9 are connected with the top ends of the two groups of baffles 8, the right ends of the springs 9 are connected with the right ends of the two groups of the baffles 3, a fixing device is arranged on the suction box 3, and the fixing device is matched and connected with the pull rod 6; through pulling pull rod 6, pull rod 6 then drives piston 5 and upwards slide in absorbing case 3, red blood cell in the left collection bag 20 then promotes left baffle 8 through hose 2 and opens, left side spring 9 then takes place elastic deformation, then red blood cell enters into absorbing case 3 inside, then red blood cell promotes right baffle 8 and opens, right side spring 9 then takes place elastic deformation, red blood cell then leads into right collection bag 1 inside through right connecting pipe 4 and hose 2, after red blood cell is leading into jack 10, through pushing pull rod 6, piston 5 then downwards slides in absorbing case 3, afterwards fix pull rod 6 through fixing device, thereby make piston 5 seal two sets of connecting pipes 4, through setting up this equipment, be convenient for with the quantitative leading-in of red blood cell in the left collection bag 20 to right collection bag 1 inside, the operation is simpler, red blood cell in the left collection bag 20 has been avoided, white blood cell and plasma mix once more, the quality of its collection separation has been improved.

The utility model discloses a two-joint bag for collecting and separating umbilical cord blood hematopoietic stem cells, which comprises a fixing frame 11 and a threaded rod 12, wherein an inserting hole 10 is formed in the upper part of the right end of a pull rod 6, the bottom end of the fixing frame 11 is connected with the top end of a suction box 3, the threaded rod 12 is in threaded connection with the fixing frame 11, and the threaded rod 12 corresponds to the inserting hole 10 in position; when the piston 5 slides to the lowest side in the suction box 3, the threaded rod 12 is screwed with the fixing frame 11 by rotating the threaded rod 12, and the threaded rod 12 is inserted into the insertion hole 10, so that the pull rod 6 is fixed, the piston 5 seals the two groups of connecting pipes 4, and white blood cells in the left collecting bag 20 are prevented from being led into the right collecting bag 1 through the hose 2.

The utility model discloses a two-joint bag for collecting and separating umbilical cord blood hematopoietic stem cells, which also comprises two groups of sealing rings 13, wherein the two groups of sealing rings 13 are respectively arranged at the left ends of two groups of baffles 8; by providing the seal ring 13, the tightness between the left baffle 8 and the hose 2 and between the right baffle 8 and the annular baffle 7 can be improved.

The utility model discloses a two-way bag for collecting and separating umbilical cord blood hematopoietic stem cells, which also comprises two groups of telescopic pipes 14 and two groups of telescopic rods 15, wherein the two groups of telescopic pipes 14 and the two groups of telescopic rods 15 are respectively positioned in two groups of springs 9, the top ends of the two groups of telescopic pipes 14 are rotationally connected with the top ends in the two groups of connecting pipes 4, the bottom ends of the two groups of telescopic rods 15 are rotationally connected with the right ends of the two groups of baffle plates 8, and the two groups of telescopic rods 15 slide in the two groups of telescopic pipes 14; by arranging the telescopic tube 14 and the telescopic rod 15, the spring 9 can be guided, and the stability of the baffle 8 is improved.

The utility model discloses a two-joint bag for collecting and separating umbilical cord blood hematopoietic stem cells, which further comprises a handle 16, wherein the handle 16 is arranged at the top end of a pull rod 6; by providing the handle 16, the operation of the pull rod 6 is facilitated.

The utility model discloses a two-joint bag for collecting and separating umbilical cord blood hematopoietic stem cells, wherein a finger groove 17 is arranged on a handle 16; by providing the finger groove 17, the comfort of the worker holding the handle 16 can be improved.

The utility model discloses a two-joint bag for collecting and separating umbilical cord blood hematopoietic stem cells, wherein the left end of a threaded rod 12 is provided with a guide angle 18; by providing the lead angle 18, insertion of the threaded rod 12 into the receptacle 10 is facilitated.

The utility model discloses a two-joint bag for collecting and separating umbilical cord blood hematopoietic stem cells, which also comprises a rotating handle 19, wherein the rotating handle 19 is arranged at the right end of a threaded rod 12; by providing a knob 19, rotation of the threaded rod 12 is facilitated.

When the dual bag for collecting and separating umbilical cord blood hematopoietic stem cells works, firstly, the pull rod 6 is pulled, the pull rod 6 drives the piston 5 to slide upwards in the suction box 3, red blood cells in the left collection bag 20 push the left baffle 8 to be opened through the hose 2, the left spring 9 is elastically deformed, then the red blood cells enter the suction box 3, then the red blood cells push the right baffle 8 to be opened, the right spring 9 is elastically deformed, the red blood cells are led into the right collection bag 1 through the right connecting pipe 4 and the hose 2, after the red blood cells are led into the jack 10, the piston 5 slides downwards in the suction box 3 through pushing the pull rod 6, then the threaded rod 12 is in threaded connection with the fixing frame 11 through rotating the threaded rod 12, the threaded rod 12 is inserted into the jack 10, so that the pull rod 6 is fixed, and the piston 5 seals the two groups of connecting pipes 4.

The two-way bag for collecting and separating the cord blood hematopoietic stem cells is a common mechanical way in the installation way, the connection way or the setting way, and can be implemented as long as the beneficial effects can be achieved.

The foregoing is merely a preferred embodiment of the present utility model, and it should be noted that it will be apparent to those skilled in the art that modifications and variations can be made without departing from the technical principles of the present utility model, and these modifications and variations should also be regarded as the scope of the utility model.

Claims

1. The utility model provides a two allies oneself with bag that cord blood hematopoietic stem cell gathered and separated which characterized in that includes right collection bag (1), hose (2), left collection bag (20) and suction means, and right collection bag (1) and left collection bag (20) are through hose (2) intercommunication, are provided with suction means on hose (2);

the suction device comprises a suction box (3), a piston (5), a pull rod (6), an annular baffle (7), two groups of baffles (8) and two groups of springs (9), the suction box (3) is installed in the middle of a hose (2), the lower parts of the left end and the right end of the suction box (3) are communicated with each other, the connecting pipe (4) are arranged on the left end and the right end of the suction box (3), the hose (2) is communicated with the two groups of connecting pipes (4), the piston (5) slides in the suction box (3), the top end of the piston (5) is connected with the bottom end of the pull rod (6), the pull rod (6) is connected with the top end of the suction box (3) in a sliding manner, the annular baffle (7) is installed in the right connecting pipe (4), the two groups of baffles (8) are rotatably installed on the two groups of connecting pipes (4), the top ends of the two groups of springs (9) are connected with the inner top ends of the two groups of connecting pipes (4), and the bottom ends of the two groups of springs (9) are connected with the right end of the two groups of baffles (8), and the fixing device is connected with the pull rod (6) in a matched manner.

2. The two-in-one bag for collecting and separating umbilical cord blood hematopoietic stem cells according to claim 1, wherein the fixing device comprises a fixing frame (11) and a threaded rod (12), the upper part of the right end of the pull rod (6) is provided with an inserting hole (10), the bottom end of the fixing frame (11) is connected with the top end of the suction box (3), the threaded rod (12) is in threaded connection with the fixing frame (11), and the threaded rod (12) corresponds to the inserting hole (10).

3. The two-way bag for collecting and separating umbilical cord blood hematopoietic stem cells according to claim 2, further comprising two sets of sealing rings (13), wherein the two sets of sealing rings (13) are respectively arranged at the left ends of the two sets of baffles (8).

4. A two-joint bag for collecting and separating umbilical cord blood hematopoietic stem cells according to claim 3, further comprising two groups of telescopic pipes (14) and two groups of telescopic rods (15), wherein the two groups of telescopic pipes (14) and the two groups of telescopic rods (15) are respectively positioned in the two groups of springs (9), the top ends of the two groups of telescopic pipes (14) are rotationally connected with the top ends in the two groups of connecting pipes (4), the bottom ends of the two groups of telescopic rods (15) are rotationally connected with the right ends of the two groups of baffle plates (8), and the two groups of telescopic rods (15) slide in the two groups of telescopic pipes (14).

5. The two-in-one bag for collecting and separating cord blood hematopoietic stem cells according to claim 4, further comprising a handle (16), wherein the handle (16) is mounted on the top end of the pull rod (6).

6. The two-pack for collecting and separating umbilical cord blood hematopoietic stem cells as claimed in claim 5, wherein the handle (16) is provided with a finger groove (17).

7. The two-way bag for collecting and separating umbilical cord blood hematopoietic stem cells as claimed in claim 6, wherein the left end of the threaded rod (12) is provided with a guide angle (18).

8. The two-in-one bag for collecting and separating cord blood hematopoietic stem cells according to claim 7, further comprising a rotary handle (19), wherein the rotary handle (19) is mounted on the right end of the threaded rod (12).