CN218900334U - Antifungal pain relieving catheter - Google Patents
Antifungal pain relieving catheter Download PDFInfo
- Publication number
- CN218900334U CN218900334U CN202222779303.0U CN202222779303U CN218900334U CN 218900334 U CN218900334 U CN 218900334U CN 202222779303 U CN202222779303 U CN 202222779303U CN 218900334 U CN218900334 U CN 218900334U
- Authority
- CN
- China
- Prior art keywords
- catheter
- antifungal
- layer
- local anesthesia
- slow release
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000000843 anti-fungal effect Effects 0.000 title claims abstract description 27
- 229940121375 antifungal agent Drugs 0.000 title claims abstract description 27
- 230000036407 pain Effects 0.000 title abstract description 17
- 239000003814 drug Substances 0.000 claims abstract description 36
- 238000002690 local anesthesia Methods 0.000 claims abstract description 33
- 230000002924 anti-infective effect Effects 0.000 claims abstract description 23
- 229940079593 drug Drugs 0.000 claims abstract description 20
- 230000000202 analgesic effect Effects 0.000 claims abstract description 13
- 239000000463 material Substances 0.000 claims description 5
- 230000000007 visual effect Effects 0.000 claims description 5
- 230000002485 urinary effect Effects 0.000 claims description 2
- 230000000694 effects Effects 0.000 description 7
- 238000000034 method Methods 0.000 description 5
- 210000001635 urinary tract Anatomy 0.000 description 4
- LEBVLXFERQHONN-UHFFFAOYSA-N 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide Chemical compound CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-UHFFFAOYSA-N 0.000 description 3
- 241000233866 Fungi Species 0.000 description 3
- 229960003150 bupivacaine Drugs 0.000 description 3
- 238000013268 sustained release Methods 0.000 description 3
- 239000012730 sustained-release form Substances 0.000 description 3
- 208000019206 urinary tract infection Diseases 0.000 description 2
- 229930183010 Amphotericin Natural products 0.000 description 1
- QGGFZZLFKABGNL-UHFFFAOYSA-N Amphotericin A Natural products OC1C(N)C(O)C(C)OC1OC1C=CC=CC=CC=CCCC=CC=CC(C)C(O)C(C)C(C)OC(=O)CC(O)CC(O)CCC(O)C(O)CC(O)CC(O)(CC(O)C2C(O)=O)OC2C1 QGGFZZLFKABGNL-UHFFFAOYSA-N 0.000 description 1
- 208000028399 Critical Illness Diseases 0.000 description 1
- 206010017533 Fungal infection Diseases 0.000 description 1
- 208000031888 Mycoses Diseases 0.000 description 1
- 229940009444 amphotericin Drugs 0.000 description 1
- APKFDSVGJQXUKY-INPOYWNPSA-N amphotericin B Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-INPOYWNPSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 239000003589 local anesthetic agent Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
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- Media Introduction/Drainage Providing Device (AREA)
Abstract
The utility model provides an antifungal pain relieving catheter, which is characterized in that: comprises a catheter body, a local anesthesia slow release layer and an anti-infection layer; wherein, the local anesthesia slow release layer is filled with local anesthesia drugs; the anti-infective layer is filled with anti-infective drugs; the local anesthesia slow release layer is arranged on the outer side of the catheter body; the anti-infection layer is arranged on the inner side of the catheter body. The catheter has antifungal and analgesic effects.
Description
Technical Field
The utility model relates to the field, in particular to an antifungal pain relieving catheter.
Background
In the existing clinical treatment, all patients of the ICU and some patients with difficult postoperative actions need to be provided with a catheter, and the following clinical manifestations exist when the catheter is used for a long time:
1. intolerance to urinary ducts, long-term use, patients can have painful and hard manifestations, and can easily generate negative emotions in the treatment process of diseases;
2. the critically ill patients who stay the catheter for a long time can also combine the problems of urinary tract infection and the like, which is not beneficial to the recovery of the body and the mind after operation.
Disclosure of Invention
The present utility model aims to overcome the above drawbacks and to provide a catheter with antifungal and analgesic effects.
The utility model provides an antifungal pain relieving catheter, which is characterized in that: comprises a catheter body, a local anesthesia slow release layer and an anti-infection layer;
wherein, the local anesthesia slow release layer is filled with local anesthesia drugs;
the anti-infective layer is filled with anti-infective drugs;
the local anesthesia slow release layer is arranged on the outer side of the catheter body;
the anti-infection layer is arranged on the inner side of the catheter body.
Further, the utility model provides an antifungal pain relieving catheter, which is further characterized in that:
micropores are uniformly distributed on the inner surface of the anti-infection layer.
Further, the utility model provides an antifungal pain relieving catheter, which is further characterized in that:
the disk with the spiral anti-infection layer is arranged on the inner surface of the catheter body.
Further, the utility model provides an antifungal pain relieving catheter, which is further characterized in that:
micropores are uniformly distributed on the outer surface of the local anesthesia slow-release layer.
Further, the utility model provides an antifungal pain relieving catheter, which is further characterized in that:
the external visual surface of the local anesthesia slow release layer is in a ladder shape.
Further, the utility model provides an antifungal pain relieving catheter, which is further characterized in that:
the external visual surface of the local anesthesia slow release layer is concave-convex.
Further, the utility model provides an antifungal pain relieving catheter, which is further characterized in that:
the local anesthesia slow release layer is a spiral disk arranged on the outer surface of the catheter body.
Further, the utility model provides an antifungal pain relieving catheter, which is further characterized in that:
the local anesthesia slow release layer is of a multi-layer structure, and the outer surface of each layer is of a microporous structure or is made of slow release materials which can be absorbed/dissolved by a human body.
Further, the utility model provides an antifungal pain relieving catheter, which is further characterized in that:
the local anesthesia slow release layer is composed of a plurality of medicine belts which are arranged in a staggered way;
the staggered medicine bands are arranged in a staggered way for the medicine bands filled with local anesthesia medicines and the medicine bands filled with anti-infection medicines.
Drawings
FIG. 1 is a schematic cross-sectional view of an antifungal analgesic catheter;
FIG. 2 is a schematic view showing a layered cross-sectional structure of a catheter for preventing fungi and relieving pain;
FIG. 3 is a schematic view showing the outer structure of a catheter for resisting fungi and relieving pain;
FIG. 4 is a schematic view showing the outer structure of a catheter for preventing fungi and relieving pain;
Detailed Description
As shown in fig. 1 and 2, the present embodiment provides an antifungal analgesic catheter comprising a catheter body 100, a local anesthetic sustained release layer 110 and an anti-infective layer 120;
wherein, the catheter body 100 is made of traditional materials and has hardness, the pipe diameter of the catheter body can be smaller than that of the existing general catheter according to actual needs, and the guiding and supporting functions are realized in the embodiment;
the local anesthesia slow release layer 110 is disposed on the outer surface of the catheter body 100 and covers the whole outer surface, and can be integrally constructed, or can be nested and sleeved on the outer surface of the catheter body 100 to form a layered structure, and the layered structure is filled with drugs with local anesthesia effects, such as: the external visual surface of the bupivacaine and other similar medicines for playing a role in local anesthesia is in a film shape, and dense micropores (such as nanoscale micropores) are distributed on the bupivacaine and other medicines, so that in the use process, the medicines slowly permeate out of the micropores under the condition that the surface of a tube body is pressed by the bupivacaine and other medicines, and the effect of slowly releasing the local anesthesia medicines in the urinary tract is achieved, so that the pain of a patient is relieved.
The anti-infection layer 120, which covers the inner surface of the catheter body 100 and covers the entire inner surface, may be integrally constructed, or may be a nested structure, which is sleeved on the inner surface of the catheter body 100 to form a layered structure, and is filled with an anti-infection (i.e., antifungal) drug, such as: amphotericin; the external view surface (i.e. the inner surface of the tube body) is in a film shape, and dense micropores (such as nano micropores) are distributed on the external view surface, so that in the using process, the medicine slowly seeps out of the micropores under the action of long-time urine flushing and external pressure in the urinary tract, the effect of slowly releasing the anti-infective medicine in the urinary tract is achieved, and the risk of urinary tract infection is reduced.
In order to improve the sustained release effect of the drug, the drug on the outer layer is prevented from being released rapidly, and as shown in fig. 3, in this embodiment, a stepped sustained release outer layer structure is also provided.
As shown in the figure, the structure is provided with a microscopic concave-convex surface, the convex surface is pressed firstly during the use process, the medicament is slowly released to carry out medicament slow release on the contact surface, and when the medicament in the convex surface gradually decreases, the medicament in the concave surface slowly flows into the convex surface to supplement, and on the other hand, the concave surface starts to formally slow release as the convex surface is aligned with the original concave surface. Thus realizing the effect of slow release by stages of distribution.
Furthermore, in view of the fact that there may be a risk of fungal infection on the outer surface, a solution with two drugs on the outer surface is also proposed in the examples. As shown in fig. 4, the local-anesthesia slow-release layer is a double-spiral (alternatively, the local-anesthesia slow-release layer can be arranged in a staggered cross bar shape or a vertical bar shape) disc and is arranged on the outer surface of the catheter body, wherein the A spiral tube is filled with local-anesthesia medicine, and the B spiral tube is filled with anti-infection medicine. In this way, in the slow release process, the effect of directly acting on the urinary tract with double drug effects can be realized.
In addition, the laminated structure arranged in a layered manner can be used for forming the outer layer, and the outer surface of each layer is of a microporous structure, so that the effect of layer-by-layer slow release is realized. Or each layer of the coating material is made of a slow release material that can be absorbed/dissolved by the human body.
Claims (9)
1. An antifungal analgesic urinary catheter, characterized by: comprises a catheter body, a local anesthesia slow release layer and an anti-infection layer;
wherein, the local anesthesia slow release layer is filled with local anesthesia drugs;
the anti-infective layer is filled with anti-infective drugs;
the local anesthesia slow release layer is arranged on the outer side of the catheter body;
the anti-infection layer is arranged on the inner side of the catheter body.
2. An antifungal analgesic catheter as defined in claim 1 wherein:
micropores are uniformly distributed on the inner surface of the anti-infection layer.
3. An antifungal analgesic catheter as defined in claim 1 wherein:
the disk with the spiral anti-infection layer is arranged on the inner surface of the catheter body.
4. An antifungal analgesic catheter as defined in claim 1 wherein:
micropores are uniformly distributed on the outer surface of the local anesthesia slow-release layer.
5. An antifungal analgesic catheter as defined in claim 1 wherein:
the external visual surface of the local anesthesia slow release layer is in a ladder shape.
6. An antifungal analgesic catheter as defined in claim 1 wherein:
the external visual surface of the local anesthesia slow release layer is concave-convex.
7. An antifungal analgesic catheter as defined in claim 1 wherein:
the local anesthesia slow release layer is a spiral disk arranged on the outer surface of the catheter body.
8. An antifungal analgesic catheter as defined in claim 1 wherein:
the local anesthesia slow release layer is of a multi-layer structure, and the outer surface of each layer is of a microporous structure or is made of slow release materials which can be absorbed/dissolved by a human body.
9. An antifungal analgesic catheter as defined in claim 1 wherein:
the local anesthesia slow release layer is composed of a plurality of medicine belts which are arranged in a staggered way;
the staggered medicine bands are arranged in a staggered way for the medicine bands filled with local anesthesia medicines and the medicine bands filled with anti-infection medicines.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222779303.0U CN218900334U (en) | 2022-10-21 | 2022-10-21 | Antifungal pain relieving catheter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222779303.0U CN218900334U (en) | 2022-10-21 | 2022-10-21 | Antifungal pain relieving catheter |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN218900334U true CN218900334U (en) | 2023-04-25 |
Family
ID=86040888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202222779303.0U Expired - Fee Related CN218900334U (en) | 2022-10-21 | 2022-10-21 | Antifungal pain relieving catheter |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN218900334U (en) |
-
2022
- 2022-10-21 CN CN202222779303.0U patent/CN218900334U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20230425 |