CN218823519U - Pretreatment equipment for mass spectrum detection - Google Patents
Pretreatment equipment for mass spectrum detection Download PDFInfo
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- CN218823519U CN218823519U CN202222350319.XU CN202222350319U CN218823519U CN 218823519 U CN218823519 U CN 218823519U CN 202222350319 U CN202222350319 U CN 202222350319U CN 218823519 U CN218823519 U CN 218823519U
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- filtration storehouse
- vertical scroll
- stirring
- mass spectrometry
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02W—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
- Y02W30/00—Technologies for solid waste management
- Y02W30/50—Reuse, recycling or recovery technologies
- Y02W30/62—Plastics recycling; Rubber recycling
Abstract
The utility model relates to a mass spectrometry detects uses preprocessing equipment, including liquid sample bottle, preliminary treatment mount and filtering component, its technical essential is: the liquid sample bottle is equipped with coniform depressed center, the preliminary treatment mount includes cylindrical filtration storehouse and support, the center of cylindrical filtration storehouse is equipped with the stirring vertical scroll and the lower extreme of stirring vertical scroll is connected with the fixed agitator motor in cylindrical filtration storehouse bottom surface center, the upper end of stirring vertical scroll is fixed with the conical hood that corresponds the coniform depressed center, the outer peripheral face of stirring vertical scroll is fixed with stirring paddle leaf, the bottom surface of cylindrical filtration storehouse is equipped with annular feed bin around agitator motor, filtering component is located the last port of annular feed bin, the bottom of annular feed bin evenly is equipped with a plurality of feed openings down, the support center is equipped with horizontal support board and the horizontal support board top is equipped with the branch appearance bottle that corresponds with the feed opening. The device solves the problem of low pretreatment efficiency before mass spectrometry, obviously improves the operation efficiency, and simultaneously ensures the filtration pretreatment quality of the sampled sample.
Description
Technical Field
The utility model relates to a mass spectrometry detection technique, concretely relates to mass spectrometry detects uses pre-processing equipment.
Background
At present, a mass spectrometry detection technology is a spectroscopic method parallel to a spectrum, generally refers to a special technology for identifying compounds by preparing, separating and detecting gas-phase ions, is widely applied to various subject fields, and has high specificity and high sensitivity.
The liquid chromatography-mass spectrometry (LC-MS) technique has become a standard detection means for small molecule sample analysis, and is a hybrid analysis instrument, in which the liquid chromatography part is used for analyzing liquid samples, and the mobile phase flows out of a solvent bottle, passes through a high performance liquid chromatography pump and an injection valve, and enters a chromatographic column, which is a long and delicate system, so that the sample entering the chromatographic system must be liquid, more importantly, no particles are mixed, and if the sample is not liquid, such as tissue samples and whole blood samples, the sample needs to be processed into liquid.
Therefore, the collected sample must be pre-filtered before mass spectrometry to avoid clogging of the subsequent detection system. However, since the sample to be pretreated needs to be eluted and loaded before the mass spectrometry detection, but the solvents and the like adopted for the elution and loading are different based on the detection requirements of various target objects, the sample separation treatment is still needed before the elution and loading, and at present, the process is mostly manual operation, and the operation efficiency is low.
Disclosure of Invention
An object of the utility model is to provide a rational in infrastructure, use reliable preprocessing equipment for mass spectrometric detection, the lower problem of pretreatment efficiency is showing and is improving operating efficiency before solving mass spectrometric analysis, guarantees the filtration pretreatment quality to the sample simultaneously.
The technical scheme of the utility model is that:
the utility model provides a mass spectrum detects uses preprocessing equipment, includes liquid sample bottle, preliminary treatment mount and filtering component, and its technical essential is: the liquid sample bottle is equipped with coniform depressed center, the preliminary treatment mount includes cylindrical filtration storehouse, locates the support of cylindrical filtration storehouse bottom periphery, the center of cylindrical filtration storehouse is equipped with the stirring vertical scroll and stirs the lower extreme of vertical scroll and is connected with the fixed agitator motor in cylindrical filtration storehouse bottom surface center, the upper end of stirring vertical scroll is fixed with the conical hood that corresponds coniform depressed center, the outer peripheral face of stirring vertical scroll is fixed with stirring paddle, the bottom surface of cylindrical filtration storehouse is equipped with annular feed bin around agitator motor, filtering component is fixed in the last port of annular feed bin, and the bottom of annular feed bin evenly is equipped with a plurality of feed openings down, the support center is equipped with horizontal support board and horizontal support board top and is equipped with the branch appearance bottle with feed opening one-to-one, be equipped with buffer spring between horizontal support board surface and the support bottom surface.
In the pretreatment equipment for mass spectrometry, the inner side wall of the annular blanking bin is a conical surface, so that blanking is facilitated.
Foretell preprocessing equipment for mass spectrometric detection, the both sides of feed opening are equipped with outer pterygoid lamina, divide the upper shed edge top of appearance bottle in outer pterygoid lamina lower surface, the horizontal support board upper surface is equipped with the corresponding positioning groove who divides the appearance bottle.
Foretell preliminary treatment equipment for mass spectrometry, the horizontal support board center is equipped with the guiding hole, the support bottom surface be equipped with guiding hole complex guide post, the left and right lateral wall of support is equipped with perpendicular guide way, the left and right edge of horizontal support board is equipped with the guide block that corresponds with perpendicular guide way.
Foretell preliminary treatment equipment for mass spectrum detection, the middle part of stirring vertical scroll in the cylindrical filtration storehouse and the lower part outside are wrapped up and are had the protective sheath, and the protective sheath lower extreme filters storehouse bottom surface integrated into one piece with cylindrical filtration, stirring paddle leaf is including being fixed in the holding ring on stirring vertical scroll upper portion, the L shape puddler of holding ring periphery is located to the symmetry, locate a plurality of horizontal puddlers on L shape puddler founds the section.
According to the pretreatment equipment for mass spectrometry, the outer peripheral surface of the liquid sample bottle is provided with the external thread, the inner peripheral surface of the upper part of the cylindrical filter bin is provided with the internal thread corresponding to the external thread, the lower edge of the conical concave bottom and the edge of the bottom surface of the liquid sample bottle are buckled into a whole by the cylindrical contact surface, and the cylindrical contact surface is provided with the sealing structure.
The pretreatment equipment for mass spectrum detection comprises a filter assembly and a filter assembly, wherein the filter assembly comprises an annular filter sieve plate and a microporous filter membrane fixed on the bottom surface of the annular filter sieve plate.
The utility model has the advantages that:
the conical top cap at the upper end of the stirring vertical shaft jacks up the conical concave bottom of the liquid sample bottle, so that a sample collected in the liquid sample bottle smoothly flows into the cylindrical filtering bin, the sample is stirred by the stirring motor, the sample enters the annular discharging bin through the filtering component at an accelerated speed, and enters the corresponding multiple sample dividing bottles through the discharging ports. In this process, utilize filtering component to filter the particulate matter that mingles with in the sample, simultaneously, for satisfying multiple target object detection demand, introduce the sample respectively in the branch appearance bottle of difference, whole process is once only accomplished, reduces artificial operation, and operating efficiency is high, has solved the lower problem of preliminary treatment efficiency before the mass spectrometry, and has avoided secondary pollution's possibility, has guaranteed the filtration preliminary treatment quality to the sample of taking a sample.
Drawings
Fig. 1 is a schematic structural diagram of the present invention;
FIG. 2 is a schematic view of the conical top cap of the present invention ejecting the conical concave bottom of the liquid sample bottle;
fig. 3 isbase:Sub>A sectional view taken along linebase:Sub>A-base:Sub>A in fig. 1.
In the figure: 1. the liquid sample bottle comprises a liquid sample bottle, 2 external threads, 3 cylindrical filter bins, 4 conical concave bottoms, 5 cylindrical contact surfaces, 6 internal threads, 7 stirring vertical shafts, 8 positioning rings, 9.L-shaped stirring rods, 10 horizontal stirring rods, 11 conical top caps, 12 sealing rings, 13 protective sleeves, 14 filter components, 15 stirring motors, 16 external wing plates, 17 supports, 18 vertical guide grooves, 19 guide blocks, 20 sample dividing bottles, 21 horizontal supporting plates, 22 buffer springs, 23 guide columns, 24 positioning grooves, 25 discharge ports and 26 annular discharge bins.
Detailed Description
The invention is described in detail according to the attached drawings.
As shown in fig. 1 to 3, the pretreatment device for mass spectrometry detection includes a liquid sample bottle 1, a pretreatment fixing frame, and a filter assembly.
Wherein, liquid sample bottle 1 is equipped with coniform depressed center 4, the preliminary treatment mount includes cylindrical filtration storehouse 3, locates the support 17 of cylindrical filtration storehouse 3 bottom periphery. The stirring device is characterized in that a stirring vertical shaft 7 is arranged at the center of the cylindrical filtering bin 3, the lower end of the stirring vertical shaft 7 is connected with a stirring motor 15 fixed at the center of the bottom surface of the cylindrical filtering bin 3, a conical top cap 11 corresponding to the conical concave bottom 4 is fixed at the upper end of the stirring vertical shaft 7, stirring blades are fixed on the peripheral surface of the stirring vertical shaft 7, and an annular discharging bin 26 is arranged on the bottom surface of the cylindrical filtering bin 3 around the stirring motor 15. Filter component 14 is fixed in the last port of feed bin 26 under the annular, and the bottom of feed bin 26 evenly is equipped with a plurality of feed openings 25 under the annular, support 17 center is equipped with horizontal support plate 21 and horizontal support plate 21 top is equipped with the branch appearance bottle 20 with feed opening 25 one-to-one. A buffer spring 22 is arranged between the surface of the horizontal support plate 21 and the bottom surface of the bracket 17.
In this embodiment, the outer peripheral face of liquid sample bottle 1 is equipped with external screw thread 2, cylindrical filter 3 upper portion inner peripheral face of storehouse is equipped with the internal thread 6 that corresponds with the external screw thread, the lower edge of circular cone form concave bottom 4 utilizes cylindrical contact surface 5 lock as an organic whole and cylindrical contact surface 5 to be equipped with seal structure with the bottom surface edge of liquid sample bottle 1, if offer the seal groove on cylindrical contact surface 5 and be equipped with sealing washer 12 in the seal groove.
The inner side wall of the annular blanking bin 26 is a conical surface so as to facilitate blanking. Outer wing plate 16 is equipped with to the both sides of feed opening 25, divide the upper mouth edge of sample bottle 20 to push up in outer wing plate 16 lower surface, horizontal support plate 21 upper surface is equipped with the positioning groove 24 that corresponds and divides sample bottle 20. The middle part and the lower part outside of stirring vertical scroll 7 in cylindrical filtration storehouse 3 are wrapped up and are had protective sheath 13, and protective sheath 13 lower extreme and 3 bottom surfaces integrated into one piece in the cylindrical filtration storehouse, stirring paddle leaf is including being fixed in holding ring 8 on stirring vertical scroll 7 upper portion, the L shape puddler 9 of 8 peripheries of symmetry locating ring, locating a plurality of horizontal mixing poles 10 on L shape puddler 9 founds the section. The filtering component 14 comprises an annular filtering sieve plate and a microporous filtering membrane fixed on the bottom surface of the annular filtering sieve plate.
The center of the horizontal support plate 21 is provided with a guide hole, the bottom surface of the support 17 is provided with a guide post 23 matched with the guide hole, the left side wall and the right side wall of the support 17 are provided with vertical guide grooves 18, and the left edge and the right edge of the horizontal support plate 21 are provided with guide blocks 19 corresponding to the vertical guide grooves 18.
The working process is as follows:
1. firstly, a liquid sample bottle 1 is connected to the upper part of a cylindrical filtering bin 3 in a threaded manner, a conical concave bottom 4 of the liquid sample bottle 1 is jacked open by a conical top cap 11 at the upper end of a stirring vertical shaft 7 in the descending process, and then a sample collected in the liquid sample bottle 1 smoothly flows into the cylindrical filtering bin 3;
2. starting a stirring motor 15 to drive a stirring paddle to stir and flow the sample in the cylindrical filtering bin 3, and accelerating the sample to enter an annular discharging bin 26 through a filtering component 14;
3. the filtered sample entering the annular blanking bin 26 enters the corresponding sample distributing bottle 20 through each blanking port 25, after the whole sample distributing process is finished, the horizontal support plate 21 is pressed, the upper port of the sample distributing bottle 20 is separated from the blanking port 25, the sample distributing bottle 20 is taken down from the horizontal support plate 21, and then the horizontal support plate 21 is released to reset under the action of the buffer spring 22.
The above detailed description of the embodiments of the present invention is only for the purpose of describing the preferred embodiments of the present invention, and should not be construed as limiting the scope of the present invention. All equivalent changes and modifications made within the scope of the present invention should be covered by the present patent.
Claims (7)
1. The utility model provides a mass spectrum detects uses preprocessing equipment, includes liquid sample bottle, preliminary treatment mount and filtering component, its characterized in that: the liquid sample bottle is equipped with coniform depressed center, the preliminary treatment mount includes cylindrical filtration storehouse, locates the support of cylindrical filtration storehouse bottom periphery, the center of cylindrical filtration storehouse is equipped with the stirring vertical scroll and stirs the lower extreme of vertical scroll and is connected with cylindrical filtration storehouse bottom surface fixed agitator motor in center, the upper end of stirring vertical scroll is fixed with the conical hood that corresponds the coniform depressed center, the outer peripheral face of stirring vertical scroll is fixed with stirring paddle leaf, the bottom surface of cylindrical filtration storehouse is equipped with annular feed bin around agitator motor, filtering component is fixed in the last port of annular feed bin, and the bottom of annular feed bin evenly is equipped with a plurality of feed openings, the support center is equipped with the branch appearance bottle that horizontal support plate and horizontal support plate top were equipped with the feed opening one-to-one, be equipped with buffer spring between horizontal support plate surface and the support bottom surface.
2. The pretreatment apparatus for mass spectrometry according to claim 1, wherein: the inner side wall of the annular discharging bin is a conical surface.
3. The pretreatment apparatus for mass spectrometry according to claim 1, wherein: the both sides of feed opening are equipped with outer pterygoid lamina, divide the upper mouth edge top of appearance bottle in outer pterygoid lamina lower surface, the horizontal support board upper surface is equipped with the corresponding positioning groove who divides the appearance bottle.
4. The pretreatment apparatus for mass spectrometry according to claim 1, wherein: the center of the horizontal support plate is provided with a guide hole, the bottom surface of the support is provided with a guide post matched with the guide hole, the left side wall and the right side wall of the support are provided with vertical guide grooves, and the left edge and the right edge of the horizontal support plate are provided with guide blocks corresponding to the vertical guide grooves.
5. The pretreatment apparatus for mass spectrometry according to claim 1, wherein: the middle part and the lower part outside of stirring vertical scroll in the cylindrical filtration storehouse are wrapped with the protective sheath, and protective sheath lower extreme and cylindrical filtration storehouse bottom surface integrated into one piece, stirring paddle leaf is including being fixed in the holding ring on stirring vertical scroll upper portion, the symmetry locate the L shape puddler of holding ring periphery, locate a plurality of horizontal puddlers on L shape puddler founds the section.
6. The pretreatment apparatus for mass spectrometry according to claim 1, wherein: the outer peripheral surface of the liquid sample bottle is provided with external threads, the inner peripheral surface of the upper part of the cylindrical filtering bin is provided with internal threads corresponding to the external threads, the lower edge of the conical concave bottom and the edge of the bottom surface of the liquid sample bottle are buckled into a whole by a cylindrical contact surface, and a sealing structure is arranged on the cylindrical contact surface.
7. The pretreatment apparatus for mass spectrometry according to claim 1, wherein: the filtering component comprises an annular filtering sieve plate and a microporous filtering membrane fixed on the bottom surface of the annular filtering sieve plate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222350319.XU CN218823519U (en) | 2022-09-05 | 2022-09-05 | Pretreatment equipment for mass spectrum detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222350319.XU CN218823519U (en) | 2022-09-05 | 2022-09-05 | Pretreatment equipment for mass spectrum detection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN218823519U true CN218823519U (en) | 2023-04-07 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202222350319.XU Active CN218823519U (en) | 2022-09-05 | 2022-09-05 | Pretreatment equipment for mass spectrum detection |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN218823519U (en) |
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2022
- 2022-09-05 CN CN202222350319.XU patent/CN218823519U/en active Active
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