CN218773904U

CN218773904U - Self-sampling device for biological sample detection, HPV self-sampling collection card and HPV self-sampling kit

Info

Publication number: CN218773904U
Application number: CN202222081673.7U
Authority: CN
Inventors: 李晓丹
Original assignee: Individual
Current assignee: Individual
Priority date: 2022-08-08
Filing date: 2022-08-08
Publication date: 2023-03-31
Anticipated expiration: 2032-08-08

Abstract

The utility model relates to the technical field of biological sample sampling, and discloses a self-sampling device for biological sample detection, an HPV self-sampling collecting card and an HPV self-sampling set, wherein the self-sampling device comprises a sampling swab and a pretreatment bottle, the sampling swab comprises a sampling head and a rod part, the pretreatment bottle is used for containing sample pretreatment liquid, and a dropping liquid pipe is detachably arranged at the position of a bottle opening of the pretreatment bottle; the body of the pretreatment bottle is provided with a soft extrusion part. The HPV self-sampling collection card comprises a sample collection card, and a plurality of water-absorbing cotton papers are arranged on the sample collection card. The individual self-sampling of the testee at home is facilitated. When the kit is applied to cervical cancer screening and sampling, a sampling swab is put into a pretreatment bottle filled with a lysate after sampling, so that DNA is released after cells are lysed; then drip into and carry out the shade on the absorbent cotton paper of sample collection card and preserve to whether utilize the suggestion of humidity display card to dry in the shade, the air mail of the follow-up sample of being convenient for can shorten the transport time greatly, reduces DNA degradation risk, and the patient can more in time obtain the detection report, reduces waiting period.

Description

Self-sampling device for biological sample detection, HPV self-sampling collection card and HPV self-sampling kit

Technical Field

The utility model relates to a biological sample sampling technical field especially relates to biological sample detects with collecting card, HPV from sampling package dress from sampling device, HPV.

Background

With the improvement of living standard of people, people have more and more requirements on body health and higher expected values, and the method is required to accurately detect various indexes of biochemistry, immunity, pathology and the like of a patient for doctors to make correct judgment in time. It also needs a convenient and fast sampling and detecting means, which is one of the reasons for the rapid development of POCT (point-of-care testing).

Biological samples collected by medical institutions at present comprise liquid or solid samples in vitro, such as urine, blood, saliva, semen, feces, hair, nails, skin, upper respiratory mucosa, vaginal mucosa, tissue fragments and the like. In order to obtain the examination result, the patient firstly needs to go to the hospital to queue and register, the doctor has an examination order, pays, samples in a queue and waits for the result, which is time-consuming; especially, the sampling queue is time-consuming and labor-consuming. Therefore, the method has great significance for improving the convenience degree of clinical examination, relieving the social medical burden, improving the doctor-patient relationship and improving the physical and psychological health level of the masses.

Taking screening of cervical cancer as an example, cervical cancer is the only cancer which can be screened by using HPV persistent infection as a cause at present. Therefore, the regular screening of the infected people, especially the high-risk infected people, is necessary for preventing cervical cancer and relieving the medical burden, and is also a measure advocated by the health economy. In the past, people need to go to hospitals to take samples and examine. With the rapid convergence of people, personal sampling at home is becoming an inevitable trend. Most of from sampling device all contain sample save liquid on the market at present, carry out the transportation cycle of sending a kind detection after the sampling long, have the risk of DNA degradation.

SUMMERY OF THE UTILITY MODEL

The utility model aims at providing a self-sampling device for biological sample detection, an HPV self-sampling collecting card and an HPV self-sampling suit, which are convenient for the individual self-sampling at home and the sample pretreatment of a testee; when the method is applied to cervical cancer screening and sampling, the problems that in the prior art, the collected HPV test sample can only be transported by land and cannot be transported by air, so that the sample transportation time is too long, and the risk of DNA degradation is high are solved.

In order to realize the technical effect, the utility model discloses a technical scheme be:

the self-sampling device for detecting the biological sample comprises a sampling swab and a pretreatment bottle, wherein the sampling swab comprises a sampling head and a rod part, and the sampling head of the sampling swab can extend into the inner cavity of the pretreatment bottle from the bottle opening of the pretreatment bottle; the pretreatment bottle is used for containing sample pretreatment liquid, and a dropping liquid pipe is detachably arranged at the bottle opening of the pretreatment bottle; the body of the pretreatment bottle is provided with a soft extrusion part.

Furthermore, a cover body capable of covering the bottle opening of the pretreatment bottle is arranged at the end, close to the pretreatment bottle, of the dropping liquid pipe, and a through hole capable of allowing liquid in the pretreatment bottle to flow into the dropping liquid pipe is formed in the position, corresponding to the dropping liquid pipe, of the cover body.

Furthermore, the end of the dropping liquid pipe far away from the bottle opening of the pretreatment bottle is detachably provided with a cover cap capable of sealing the liquid outlet end of the dropping liquid pipe.

For realizing the technical effect, the utility model also provides HPV is from sampling collection card, including sample collection card, install a plurality of cotton paper that absorb water on the sample collection card.

Furthermore, a humidity color card is pasted on the sample collection card and is in contact with the edge of the absorbent cotton paper.

Further, a sample information filling area or an identification code pasting area is arranged on the sample collecting card.

Furthermore, the sample collecting card is at least provided with two bending parts for drawing together and fixing two ends or two edges of one edge of the collecting card after bending to form a three-dimensional structure.

Furthermore, the collecting card is fixed by adopting viscose at the close position, or the matched clamping head and the clamping groove are detachably connected.

For realizing the technical effect, the utility model also provides an HPV is from sampling suit, including HPV from sampling device to and HPV collect the card from the sampling, HPV from sampling device and HPV collect the card from the sampling and set up in suit box or suit bag.

Further, the glove box also comprises disposable gloves arranged in the packing box or the packing bag.

Compared with the prior art, the utility model discloses the beneficial effect who possesses is:

1. sampling by using a sampling swab, and extending a sampling head of the sampling swab into a pretreatment bottle which is filled with pretreatment liquid in advance to realize pretreatment on a sample collected by the sampling swab; when taking out the sampling swab from the preliminary treatment bottle, can twist dry the swab through the portion of squeezing of extrusion body, avoid the problem that a large amount of samples were taken out by the sampling head after the sampling swab takes out, be favorable to detecting.

2. When the device is applied to cervical cancer screening and sampling, the liquid in the pretreatment bottle is dripped onto the absorbent cotton paper on the sample collection card through the extrusion part of the extrusion bottle body to carry out shade drying treatment; then, the sample collection card envelope of the sample shade-dried absorbent cotton paper is mailed by air, so that the transportation time can be greatly shortened, the risk of DNA degradation is reduced, the patient can obtain a report more timely, and the waiting period is shortened.

Drawings

Fig. 1 is a schematic structural diagram of the HPV self-sampling device of the present invention;

FIG. 2 is a schematic structural diagram of the HPV self-sampling collection card of the present invention;

fig. 3 is a schematic diagram of a sample collection card enclosing a three-dimensional structure in example 2 or example 3.

Wherein, 1, sampling a swab; 2. pre-treating the bottle; 3. a dropping tube; 4. a cover body; 5. capping; 6. a sample collection card; 7. absorbent cotton paper; 8. a humidity color rendering card; 9. an information filling area; 10. an identification code pasting area; 11. a bending part; 12. clamping a head; 13. a card slot; 14. a pressing part.

Detailed Description

The present invention will be described in further detail with reference to the following embodiments and accompanying drawings. However, it should not be understood that the scope of the above-mentioned subject matter is limited to the following embodiments, and all the technologies realized based on the present invention are within the scope of the present invention.

Example 1

Referring to fig. 1, the self-sampling device for biological sample detection comprises a sampling swab 1 and a pretreatment bottle 2, wherein the sampling swab 1 comprises a sampling head and a rod part, and the sampling head of the sampling swab 1 can extend into the inner cavity of the pretreatment bottle 2 from the bottle opening of the pretreatment bottle 2; the pretreatment bottle 2 is used for containing sample pretreatment liquid, and a dropping liquid pipe 3 is detachably arranged at the bottle opening of the pretreatment bottle 2; the body of the pretreatment bottle 2 is provided with a soft squeezing part 14.

In this embodiment, the HPV sample is sampled, and in this embodiment, the sampling swab 1 is inserted into the vaginal part to be sampled, and the sampling head of the sampling swab 1 is inserted into the pretreatment bottle 2 which is filled with the pretreatment solution in advance; the pretreatment solution in this embodiment is a cell lysate for lysing a tissue sample collected by the sampling swab 1, and thus, the sample collected by the sampling swab 1 is pretreated. In this embodiment, after sampling, the sampling head of the sampling swab 1 is stirred in the lysate for 10 to 15 times, and when the sampling swab 1 is taken out from the pretreatment bottle 2, the swab can be wrung by squeezing the squeezing portion 14 of the bottle body, so that the problem that a large amount of samples are taken out by the sampling head after the sampling swab 1 is taken out is avoided, and detection is facilitated.

After the tissue sample is cracked, a dropping liquid tube 3 is installed at the bottle opening of the pretreatment bottle 2 and used for dropping cracked cells for storage or cell amplification, so that the subsequent test is facilitated. The squeezing part 14 of the pretreatment bottle 2 can conveniently squeeze the liquid after the cracking out and drip from the dropping pipe 3. The front end of dropping liquid pipe 3 is the beak portion, conveniently drips out liquid, also can stretch into pretreatment bottle 2 at sampling swab 1 and then install dropping liquid pipe 3 promptly, plays the effect of interim lid, reduces the risk of suspended impurity in the air or microorganism entering into the interior contaminated sample of pretreatment bottle 2.

The body of the pretreatment bottle 2 in this embodiment is made of silicone or rubber, and the squeezing portion 14 is the entire body. The squeezing part 14 can be made of silica gel or rubber, and other parts of the pretreatment bottle 2 are made of hard materials.

The end of the dropping liquid pipe 3 close to the pretreatment bottle 2 is provided with a cover body 4 which can cover the bottle mouth of the pretreatment bottle 2, and the cover body 4 is provided with a through hole which can allow the liquid in the pretreatment bottle 2 to flow into the dropping liquid pipe 3 at the position corresponding to the dropping liquid pipe 3. The cover body 4 and the bottle mouth of the pretreatment bottle 2 are detachably fixed in a clamping, sleeving or threaded manner, so that the dropping liquid tube 3 is convenient to disassemble and assemble; in the embodiment, a schematic structure of a threaded connection is shown, as shown in fig. 1.

The end of the dropping liquid pipe 3 far away from the bottle opening of the pretreatment bottle 2 is detachably provided with a cap 5 which can seal the liquid outlet end of the dropping liquid pipe 3 and can be used for encapsulating pretreatment liquid in the pretreatment bottle 2 in advance. Before the use (before the product is packaged), cell lysate or other liquid for sample pretreatment can be packaged in the pretreatment bottle 2 in advance, the cover body 4 is adopted for screwing, and the end of the dropping liquid pipe 3 is sealed by the cover cap 5, so that the liquid is prevented from leaking. The cover body 4 is unscrewed, so that the sampling head of the sampling swab 1 can conveniently extend into the cover body; when the liquid is dripped out, the liquid dripping tube 3 is installed, and the cap 5 at the end of the liquid dripping tube 3 is opened, so that the liquid can be dripped out smoothly. The block 5 material can be silica gel or rubber material, and the leakproofness is good.

Example 2

Referring to fig. 1-3, the hpv self-sampling collection card includes a sample collection card 6, and a plurality of absorbent tissues 7 are mounted on the sample collection card 6.

After the sample collected by the sampling swab 1 is pretreated in the pretreatment bottle 2 of the example 1, the liquid is dripped on the water-absorbing cotton paper 7 on the sample collecting card 6 through the dripping tube 3 for drying; then, the sample collection card 6 of the sample shade-dried absorbent cotton paper 7 is packaged into an envelope for air mailing, so that the transportation time can be greatly shortened, the risk of DNA degradation is reduced, the patient can obtain a report more timely, and the waiting period is shortened.

In this embodiment, a humidity color card 8 is attached to the sample collection card 6, and the humidity color card 8 contacts with the edge of the absorbent cotton paper 7. After liquid is dripped on the absorbent cotton paper 7, the humidity color card is soaked by the liquid, the humidity color card 8 generates a color change reaction due to the change of the humidity, when a test person judges that the color indicated by the humidity color card 8 corresponds to a dry state or the humidity is lower, the test person can put the absorbent cotton paper 7 with the liquid in the shade and dry, and the test person can carry out envelope filling and mailing.

The position of the sample collection card 6 where the absorbent cotton is arranged is provided with a groove, and the absorbent cotton paper 7 is positioned in the groove. The absorbent cotton paper 7 is arranged in the groove, and the area is fixed, so that a test person can conveniently identify the dripping area. The humidity color development card 8 in this embodiment is also disposed in the groove.

The sample collection card 6 is also provided with a sample information filling area 9 or an identification code attaching area 10. The sample information filling area 9 is convenient for the testee to fill in the sample sampling information; such as name, age, date of sampling, etc.; the identification code pasting region 10 is used for pasting scanning information such as a bar code or a two-dimensional code corresponding to the sample. The method is convenient for automatic identification, registration or information checking in the detection process, and avoids the problem of sample confusion.

The sample collecting card 6 is at least provided with two bending parts 11 for closing two ends or two edges of the collecting card after bending to form a three-dimensional structure. The sample collection card 6 is folded along the bending part 11 and fixed to form a three-dimensional structure, so that the water-absorbing cotton paper 7 can be far away from the table-board in the shade drying process. The position of the collecting card close to the collecting card is fixed by adopting viscose glue, or the collecting card is detachably connected with a clamping head 12 and a clamping groove 13 which are matched with each other. The sample collection card 6 in this embodiment is a rectangular structure, and is provided with two bending portions 11 at intervals along the width direction, and after bending, a three-dimensional triangular prism structure is formed, and two sides which are closed together are fixed by gluing or a clamping groove 13 of a clamping head 12. Card 6 is collected to sample in this embodiment chooses ordinary hard board for use, draws close the position and fixes with dop 12 draw-in groove 13, and dop 12, draw-in groove 13 and sample are collected card 6 integrated into one piece, the processing of being convenient for.

Example 3

Referring to fig. 1-3, the HPV self-sampling kit includes an HPV self-sampling device and an HPV self-sampling collection card, which are disposed in a kit or a bag (not shown). For personal at-home self-sampling of subjects. After sampling, putting the sampling swab 1 into a pretreatment bottle 2 filled with lysate, so that the tissue is dispersed into cells after cracking; then the mixture is dripped into the sample collection card 6 for drying in the shade for storage, thereby facilitating the air transportation of the subsequent samples.

The HPV self-sampling kit in this embodiment further includes disposable gloves (not shown in the figure) disposed inside the kit box or the kit bag, and the subject wears the disposable gloves to perform self-sampling, which is clean and sanitary, and reduces the risk of infection.

Other parts in this embodiment are the same as those in

embodiments

1 and 2, respectively, and are not described herein again.

The present invention is not limited to the above preferred embodiments, and any modifications, equivalent replacements, and improvements made within the spirit and principle of the present invention should be included within the protection scope of the present invention.

Claims

1. Biological sample detects uses from sampling device which characterized in that: the sampling swab (1) comprises a sampling swab (1) and a pretreatment bottle (2), wherein the sampling swab (1) comprises a sampling head and a rod part, and the sampling head of the sampling swab (1) can extend into the inner cavity of the pretreatment bottle (2) from the bottle opening of the pretreatment bottle (2); the pretreatment bottle (2) is used for containing sample pretreatment liquid, and a dropping liquid pipe (3) is detachably mounted at the opening of the pretreatment bottle (2); the body of the pretreatment bottle (2) is provided with a soft extrusion part (14).

2. The self-sampling device for biological sample testing according to claim 1, wherein: the end close to the pretreatment bottle (2) on the dropping liquid pipe (3) is provided with a cover body (4) capable of covering the bottle mouth of the pretreatment bottle (2), and a through hole for the liquid in the pretreatment bottle (2) to flow into the dropping liquid pipe (3) is arranged at the position corresponding to the dropping liquid pipe (3) on the cover body (4).

3. The self-sampling device for testing a biological sample according to claim 1, wherein: the end of the dropping liquid pipe (3) far away from the bottle mouth of the pretreatment bottle (2) is detachably provided with a cover cap (5) capable of sealing the liquid outlet end of the dropping liquid pipe (3).

HPV self-sampling collection card, its characterized in that: comprises a sample collection card (6), wherein a plurality of water-absorbing cotton papers (7) are arranged on the sample collection card (6).

5. The HPV self-sampling collection card according to claim 4, wherein: the sample collection card (6) is pasted with a humidity color card (8), and the humidity color card (8) is in contact with the edge of the absorbent cotton paper (7).

6. The HPV self-sampling collection card according to claim 4, wherein: the sample collecting card (6) is also provided with a sample information filling area (9) or an identification code pasting area (10).

7. HPV self-sampling collection card according to any of claims 4-6, characterised in that: the sample collecting card (6) is at least provided with two bending parts (11) for drawing two ends or two edges of one edge of the collecting card close and fixing to form a three-dimensional structure after bending.

8. The HPV self-sampling collection card of claim 7, wherein: the collecting card is fixed by adopting viscose at the closing position, or detachably connected by adopting a matched clamping head (12) and a clamping groove (13).

HPV self-sampling suit, its characterized in that: comprising the HPV self-sampling device of claim 1 and the HPV self-sampling collection card of claim 4 arranged in a kit or a bag-in-a-package.

10. The HPV self-sampling kit according to claim 9, wherein: also comprises disposable gloves arranged in the suit box or the suit bag.