CN218725650U

CN218725650U - Sampling assembly and sample analyzer

Info

Publication number: CN218725650U
Application number: CN202222295639.XU
Authority: CN
Inventors: 廖闽
Original assignee: Shenzhen Dymind Biotechnology Co Ltd
Current assignee: Shenzhen Dymind Biotechnology Co Ltd
Priority date: 2022-08-29
Filing date: 2022-08-29
Publication date: 2023-03-24
Anticipated expiration: 2032-08-29

Abstract

The application discloses sampling subassembly and sample analysis appearance, this sampling subassembly include sample collection container and sample frame. The sample collection container comprises an outer shell and a sampling pipe, and the sampling pipe is partially arranged in the accommodating space of the outer shell; the sample rack is provided with a fixed upright post, and a first accommodating groove is formed in the fixed upright post; the sample collection container is arranged on the sample frame, the fixed upright post is arranged in the containing space, and at least part of the sampling pipe is positioned in the first containing groove. The utility model provides a sample collection container is fixed in the sample frame through fixed stand on, and the sampling pipe is located the first storage tank of fixed stand, reduces the clearance error of sample frame and sampling pipe, and the striker when effectively preventing sample analyzer's sampling needle from inhaling the appearance improves the sample precision of sampling needle.

Description

Sampling assembly and sample analyzer

Technical Field

The application relates to the technical field of medical equipment, in particular to a sampling assembly and a sample analyzer.

Background

In the field of medical diagnosis, a sample analyzer is used for detecting samples such as blood, and the samples are generally arranged on a sample rack and transported by a rail, a belt and the like, so that the streamlined automatic detection operation is realized.

Among the prior art, there is the clearance error between sample frame and sampling pipe, and when the inner chamber of sampling pipe was less, the clearance error between sample frame and sampling pipe leads to the sampling needle firing pin easily, influences the sampling precision of sampling needle, is unfavorable for realizing sample analyzer's automated inspection.

SUMMERY OF THE UTILITY MODEL

The application provides a sampling subassembly and sample analysis appearance to solve the not high technical problem of sampling precision among the prior art.

In order to solve the above problem, the present application provides a first technical solution, including: a sampling assembly is provided that includes a sample collection container and a sample rack. The sample collection container comprises an outer shell and a sampling pipe, wherein the sampling pipe is partially arranged in the accommodating space of the outer shell; the sample rack is provided with a fixed upright post, and a first accommodating groove is formed in the fixed upright post; when the sample frame is matched with the sample collecting container, the fixed upright post is positioned in the accommodating space, and at least part of the sampling pipe is positioned in the first accommodating groove.

Optionally, the sample rack is provided with a second accommodating groove, the fixed upright column is arranged in the second accommodating groove, the outer shell of the sample collection container is located in the second accommodating groove, and the inner side wall of the outer shell is abutted to the outer side wall of the fixed upright column.

Optionally, the distance between the sampling tube and the outer shell is equal to the wall thickness of the fixed post.

Optionally, one side of the sample rack, which is away from the fixed upright, is provided with a third accommodating groove, and the third accommodating groove is provided with a capacity increasing sheet.

Optionally, the sample rack includes a sample identifier, and the sample identifier is disposed corresponding to the fixed pillar.

Optionally, the sample rack is provided with an identification code.

Optionally, the outer side wall of the sampling tube is provided with a supporting part, the sampling tube is fixed to the outer shell through the supporting part, and a gap is formed between the sampling tube and the outer shell.

Optionally, the sampling tube has an internal diameter of between 2mm and 5 mm.

In order to solve the above problem, the present application provides a second technical solution, including: there is provided a sample analyzer comprising the sampling assembly and the detection assembly as described above, wherein the detection assembly is provided with a sample introduction region, and the sampling assembly is used for introducing a sample into the sample introduction region, so that the detection assembly detects a sample of the sampling tube.

Optionally, the sample analyzer comprises a centrifugation assembly for centrifuging the sample of the sampling tube.

The application provides a sampling subassembly and sample analysis appearance, this sampling subassembly includes sample collection container and sample frame. The sample collection container comprises an outer shell and a sampling pipe, and the sampling pipe is partially arranged in the accommodating space of the outer shell; the sample rack is provided with a fixed upright post, and a first accommodating groove is formed in the fixed upright post; when the sample frame is matched with the sample collecting container, the fixed upright post is positioned in the accommodating space, and at least part of the sampling pipe is positioned in the first accommodating groove. The utility model provides a sample collection container is fixed in the sample frame through fixed stand on, and the sampling pipe is located the first storage tank of fixed stand, reduces the clearance error of sample frame and sampling pipe, and the striker when effectively preventing sample analyzer's sampling needle from inhaling the appearance improves the sample precision of sampling needle.

Drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts. Wherein:

FIG. 1 is a schematic structural diagram of an embodiment of a sampling assembly provided herein;

FIG. 2 is a schematic structural diagram of an embodiment of a sample rack provided herein;

FIG. 3 is a schematic structural view of another embodiment of a sample rack provided herein;

fig. 4 is a schematic structural view of an embodiment of a sample collection container provided herein.

Detailed Description

In order to make the aforementioned objects, features and advantages of the present application more comprehensible, embodiments accompanying the present application are described in detail below with reference to the accompanying drawings. It is to be understood that the specific embodiments described herein are merely illustrative of the application and are not limiting of the application. It should be further noted that, for the convenience of description, only some of the structures associated with the present application are shown in the drawings, not all of them. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

The terms "first", "second", etc. in this application are used to distinguish between different objects and not to describe a particular order. Furthermore, the terms "include" and "provided," as well as any variations thereof, are intended to cover non-exclusive inclusions. For example, a process, method, system, article, or apparatus that comprises a list of steps or elements is not limited to only those steps or elements listed, but may alternatively include other steps or elements not listed, or inherent to such process, method, article, or apparatus.

Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein can be combined with other embodiments.

Referring to fig. 1-3, fig. 1 is a schematic structural diagram of an embodiment of a sampling assembly provided in the present application, fig. 2 is a schematic structural diagram of an embodiment of a sample rack provided in the present application, and fig. 3 is a schematic structural diagram of another embodiment of a sample rack provided in the present application.

The application firstly provides a sampling assembly, the sampling assembly is applied to a sample analyzer, the sample analyzer can be an immunoassay analyzer, specifically, the immunoassay analyzer can be a chemiluminescence analyzer, and can also be a fluorescence immunoassay analyzer, and the sampling assembly is not limited specifically here.

As shown in fig. 1, the sampling assembly 10 of the present embodiment includes a sample collection container 100, a sample rack 200, and a sampling needle; the specimen collection container 100 is used to collect and contain a specimen; the sample rack 200 is used to hold the sample collection container 100; the sampling needle is used to aspirate a sample from the sample collection container 100.

The sample collection container 100 comprises an outer shell 140 and a sampling tube 110, wherein the sampling tube 110 is partially arranged in the accommodating space of the outer shell 140; the sample rack 200 is provided with a fixed upright column 210, and a first accommodating groove 211 is formed in the fixed upright column 210; when the sample collection container 100 is fitted to the sample rack 200, the fixing post 210 is located in the accommodating space, and the sampling tube 110 is at least partially located in the first accommodating groove 211. Wherein the fit of the sample rack 200 to the sample collection container 100 may represent the state of the sample collection container 100 when in the sample rack 200.

The sample collection container 100 includes a sampling tube 110, a portion of the sampling tube 110 is disposed in the accommodating space of the outer housing 140, a portion of the sampling tube 110 away from the accommodating space is provided with an opening, a sample enters the sampling tube 110 through the opening, and the sampling tube 110 is used for accommodating the sample. In an alternative embodiment, depending on the testing item and the storage condition, the sample tube 110 may further contain an anticoagulant, a coagulant, etc. to meet the testing requirements of the sample in different testing items.

The sample rack 200 is provided with a fixed upright column 210, and a first accommodating groove 211 is provided in the fixed upright column 210, in an alternative embodiment, the first accommodating groove 211 may be, but is not limited to, a cylindrical accommodating space, and the first accommodating groove 211 is provided coaxially with the fixed upright column 210; preferably, the fixed post 210 is a metal post. When the sample collection container 100 is mounted on the sample rack 200, the fixing post 210 is disposed in the accommodating space of the outer housing 140, and the sampling tube 110 is located in the first accommodating groove 211, so that the sample collection container 100 is fixed to the sample rack 200.

When the sampling component 10 is sampled and analyzed by the sample analyzer, the sampling component 10 is conveyed to a sample injection area of the sample analyzer, the sampling needle is downwards extended to a certain height into the sampling tube 110, when the sampling needle touches a sample solution or a sample liquid surface, the capacitance value of the needle body of the sampling needle can be specifically changed, after the sample analyzer catches the capacitance change value of the sampling needle, the liquid surface position of the sample in the sampling tube 110 can be judged, according to the liquid absorption amount set by the sample analyzer, the sampling needle can be controlled by the sample analyzer to continuously descend by a certain height, in the process, when the inner cavity of the sampling tube 110 is small, in order to ensure the stability of the liquid surface detection of the sampling needle, the gap error between the sampling tube 110 and the sample frame 200 needs to be controlled within a certain range, so as to prevent the sampling needle from being collided when the sampling needle absorbs the sample. The clearance between the sampling tube 110 and the sample rack 200 is small, and the clearance error between the sample rack 200 and the sampling tube 110 can be effectively reduced.

Further, sampling tube 110 is located fixed stand 210's first storage tank 211, the range of change of liquid capacitance value when can increase the sampling needle and visit down, make the sampling needle contact the range of change of capacitance value that liquid produced be greater than the range of change of capacitance value when there is not fixed stand 210, improve the sensitivity that the sampling needle liquid level was surveyed, improve the liquid volume lower limit that the sampling needle liquid level was surveyed, and then make the capacity of sampling tube 110 can design littleer, can reduce the centrifugation time when the sample carries out centrifugal operation, improve the efficiency of sample collection and detection. The inventor of the present application found in the experimental process that the volume of the sampling tube 110 can be set to 60-100 μ L, the volume of the sample can be sufficient for completing the centrifugation and testing operations of the sample analyzer, and the centrifugation time of the sample can be shortened to 100-300s during the centrifugation operation, which can significantly reduce the centrifugation time and improve the efficiency of sample analysis.

In the present embodiment, the sampling assembly 10 of the present embodiment includes a sample collection container 100 and a sample rack 200. The sample collection container 100 comprises an outer shell 140 and a sampling tube 110, wherein the sampling tube 110 is partially arranged in the accommodating space of the outer shell 140; the sample rack 200 is provided with a fixed upright column 210, and a first accommodating groove 211 is formed in the fixed upright column 210; the sample collection container 100 is disposed in the sample rack 200, the fixing post 210 is disposed in the accommodating space, and at least a portion of the sampling tube 110 is disposed in the first accommodating groove 211. This sample collection container 100 is fixed in sample frame 200 through fixed stand 210 on, and sampling tube 110 is located fixed stand 210's first storage tank 211, reduces sample frame 200 and sampling tube 110's clearance error, striker when effectively preventing sample analyzer's sampling needle from inhaling the appearance, improves the sampling precision of sampling needle.

Optionally, the sample rack 200 is provided with a second receiving groove 212, the fixed upright 210 is disposed in the second receiving groove 212, the outer shell 140 of the sample collection container 100 is located in the second receiving groove 212, and the inner sidewall of the outer shell 140 abuts against the outer sidewall of the fixed upright 210.

Specifically, as shown in fig. 2, the fixed column 210 and the outer shell 140 are both located in the second receiving groove 212, the inner sidewall of the outer shell 140 abuts against the outer sidewall of the fixed column 210, and the sampling tube 110 is located in the first receiving groove 211 of the fixed column 210, so that the sample collection container 100 is fixed to the sample rack 200 by the abutment of the outer shell 140 against the fixed column 210.

Further, the distance between the sampling tube 110 and the outer housing 140 is equal to the wall thickness of the stationary post 210.

The wall thickness of the fixed upright column 210 is the thickness of the fixed upright column 210 after the first accommodating groove 211 is formed, the distance between the sampling tube 110 and the outer shell 140 is equal to the wall thickness of the fixed upright column 210, namely, the inner side wall of the outer shell 140 is abutted against the outer side wall of the fixed upright column 210, the outer side wall of the sampling tube 110 is abutted against the inner side wall of the first accommodating groove 211 of the fixed upright column 210, and the sample collecting container 100 is fixed to the sample frame 200 through the outer shell 140 and the abutment of the sampling tube 110 and the fixed upright column 210.

In the embodiment of the present application, the inner sidewall of the outer shell 140 of the sampling assembly 10 of the present embodiment abuts against the outer sidewall of the fixed column 210, the distance between the sampling tube 110 and the outer shell 140 is equal to the wall thickness of the fixed column 210, and by abutting the outer shell 140, the sampling tube 110 and the fixed column 210, the gap error between the sample rack 200 and the sampling tube 110 is further reduced, and the sampling precision of the sampling needle is improved.

Optionally, a third receiving groove (not shown) is disposed on a side of the sample rack 200 away from the fixing upright 210, and the third receiving groove is disposed with the capacity increasing piece 220.

The sample holder 200 is provided with a fixed upright column 210, and a third accommodating groove is formed in the bottom part far away from the fixed upright column 210, the third accommodating groove is used for accommodating a capacitance increasing sheet 220, and the capacitance increasing sheet 220 is used for increasing the capacitance value variation amplitude during the liquid level detection of the sampling needle.

Specifically, the capacity-increasing sheet 220 is a sheet-shaped or block-shaped structure disposed in the third receiving groove, and the shape of the capacity-increasing sheet may be circular, square, polygonal, etc., and the size of the capacity-increasing sheet 220 needs to ensure that the range thereof can cover all the fixing pillars 210 on the sample rack 200, and the specific configuration manner is not limited. The compatibilizer sheet 220 includes, but is not limited to, a metal sheet, a rubber sheet, and the like.

Optionally, the sample rack 200 includes a sample identifier 230, and the sample identifier 230 is disposed corresponding to the fixing post 210.

Specifically, as shown in fig. 3, the sample rack 200 may be provided with a plurality of fixed columns 210, which are combined with the sampling tubes 110 of the plurality of sample collection containers 100, so as to implement the detection of a plurality of samples by the sample analyzer, thereby improving the efficiency of sample detection. In order to distinguish a plurality of samples, the sample rack 200 is provided with sample marks 230, and the sample marks 230 correspond to the fixed columns 210 one by one. In alternative embodiments, the sample identifier 230 may be a number, letter, etc., and is not specifically limited herein.

Optionally, the sample rack 200 is provided with an identification code (not shown).

As shown in fig. 2, the sample rack 200 is provided with a barcode pasting area 240, the barcode pasting area 240 is used for pasting an identification code, the identification code is used for identifying the type of the sample rack 200, and the type of the sample rack 200 may be set corresponding to the analysis items made by the sample analyzer. In an alternative embodiment, the sample collection container 100 is provided with a sample barcode, which is used to identify the numbered barcode of the sample. In particular, the identification code and sample barcode include, but are not limited to, a two-dimensional code, a barcode, and the like.

When the sampling assembly 10 enters the sample analyzer for detection, the sample analyzer scans and identifies the identification code of the sample rack 200 and the sample bar code of the sample collection container 100, so as to realize automatic code scanning on-machine detection of the sample and improve the efficiency of sample analysis.

In the embodiment of the present application, the sample rack 200 of the sampling assembly 10 of the present embodiment is provided with the sample identifier 230, so that the sample collection containers 100 can be conveniently inserted into the sample rack 200 in a one-to-one correspondence manner, and the loading efficiency of the sample collection containers 100 is improved; the sample rack 200 is provided with an identification code, and the sample analyzer can scan and identify the identification code of the sample rack 200 and the sample bar code of the sample collection container 100, so that automatic on-machine detection of the sample analyzer is realized, and the sample analysis efficiency is improved.

Referring to fig. 4, fig. 4 is a schematic structural diagram of an embodiment of a sample collection container provided in the present application. As shown in fig. 4, the outer side wall of the sampling tube 110 is provided with a support portion 150, the sampling tube 110 is fixed to the outer housing 140 through the support portion 150, and a gap is formed between the sampling tube 110 and the outer housing 140.

The outer shell 140 of the sample collection container 100 forms an accommodating space, the sampling tube 110 is detachably fixed to the outer shell 140 by a support portion 150 provided on an outer side wall, and the support portion 150 functions to connect the sampling tube 110 and the outer shell 140. A gap is formed between the sampling tube 110 and the outer shell 140, and the fixing post 210 of the sample rack 200 is located at the gap between the sampling tube 110 and the outer shell 140, so that the inner side wall of the outer shell 140 is abutted against the outer side wall of the fixing post 210.

Optionally, the sampling tube 110 has an internal diameter of between 2mm and 5 mm.

Specifically, the interior of the sampling tube 110 is in a pore shape, the range of the internal diameter is 2mm-5mm, and compared with the traditional sample tube, the internal size of the sampling tube 110 is smaller, which is beneficial to increasing the height of the sample with the same volume. Because the sample generally need detect after the centrifugation after the sample sampling, during the detection, the sampling needle can drop by a certain height and absorb the sample of corresponding part after the centrifugation in sampling pipe 110, when the height of sample is great, can reduce the risk that the sampling needle inhales other part samples. For example, when the sample is a blood sample, serum or plasma is formed after the blood sample is centrifuged, and the inside of the sampling tube 110 has a fine pore shape, so that the height of the serum or plasma in the sampling tube 110 can be increased, and the risk of blood cells being sucked by a sampling needle during sampling can be reduced.

Alternatively, the height of the sampling tube 110 may be set according to the sampling requirement, for example, when the sample is used for a test item with a large sample test amount, the height of the sampling tube 110 may be set to be larger so that the capacity of the sampling tube 110 meets the sample requirement, and herein, the height of the sampling tube 110 is not particularly limited.

The present application further proposes a sample analyzer (not shown), which comprises the sampling component 10 according to any of the above embodiments and a detection component (not shown), wherein the detection component is provided with a sample inlet region, and the sampling component 10 is used for injecting a sample into the sample inlet region, so that the detection component detects a sample in the sampling tube 110.

The sampling assembly 10 includes a sampling needle (not shown) for aspirating a sample in the sampling tube 110, and a movement module (not shown) for causing the detection assembly to detect the sample; the moving module is used for moving the sample collection container 100 to the sample rack 200, and moving the sample rack 200 including the sample collection container 100 to the sample injection region of the detection assembly, so as to realize the automatic sample injection detection of the sample analyzer.

Optionally, the sample analyzer includes a centrifugation assembly (not shown) for centrifuging the sample from the sampling tube 110.

Specifically, after the sample collection container 100 is completely sampled, the mobile module of the sampling assembly 10 transports the sample collection container 100 to the centrifugation assembly, the centrifugation assembly sets a corresponding centrifugation time according to the volume of the sampling tube 110, and the centrifugation assembly performs a centrifugation operation on the sample, so that the centrifuged sample in the sampling tube 110 is in a separated state and is suitable for detection. After the centrifugation is accomplished, remove the module and transport sample collection container 100 after the centrifugation to sample frame 200 on to transport sampling subassembly 10 to sample analyzer's the district that advances, sample analyzer transfers the sampling needle behind code recognition identification code and the sample bar code, and the sampling needle falls to the take the altitude of sampling tube 110, and when the sampling needle contacted the liquid level of sample or sample, sample analyzer took liquid to the sample according to the capacitance value change of sampling needle, and detected the sample of imbibition.

Further, the sample analyzer still includes the washing subassembly, washs the subassembly and is used for wasing the sampling needle after absorbing the sample. The cleaning component comprises a cleaning swab, a cleaning liquid storage device and a waste liquid tank; the cleaning swab comprises a liquid inlet end and a liquid outlet end and is used for cleaning the inner wall and the outer wall of the sampling needle in a matching manner; the waste liquid tank is connected with the liquid outlet end of the cleaning swab and is used for collecting the cleaning waste liquid during cleaning; the cleaning liquid storage device is connected with the liquid outlet end of the cleaning swab and used for providing cleaning liquid. The inside and outside cleaning mode can improve the cleanliness of the sampling needle and improve the detection precision of the sample analyzer.

Different from the prior art, the sampling tube 110 of the sampling assembly 10 provided by the present application is at least partially located in the first receiving groove 211 of the fixed column 210, so that the gap error between the sample rack 200 and the sampling tube 110 can be reduced, the sample needle of the sample analyzer is effectively prevented from being struck when absorbing the sample, and the sampling precision of the sampling needle is improved; and first storage tank 211 can increase the liquid capacitance value variation range when the sampling needle probes downwards, improves the sensitivity of liquid level detection of the sampling needle.

The above description is only for the purpose of illustrating embodiments of the present application and is not intended to limit the scope of the present application, and all modifications of equivalent structures and equivalent processes, which are made by the contents of the specification and the drawings of the present application or are directly or indirectly applied to other related technical fields, are also included in the scope of the present application.

Claims

1. A sampling assembly, comprising:

the sample collection container comprises an outer shell and a sampling pipe, wherein the sampling pipe is partially arranged in the accommodating space of the outer shell;

the sample rack is provided with a fixed upright post, and a first accommodating groove is formed in the fixed upright post;

when the sample rack is matched with the sample collection container, the fixed upright is positioned in the accommodating space, and at least part of the sampling pipe is positioned in the first accommodating groove.

2. The sampling assembly of claim 1,

the sample frame is provided with a second accommodating groove, the fixed stand column is arranged in the second accommodating groove, the outer shell of the sample collecting container is located in the second accommodating groove, and the inner side wall of the outer shell is abutted to the outer side wall of the fixed stand column.

3. The sampling assembly of claim 2,

the distance between the sampling pipe and the outer shell is equal to the wall thickness of the fixed upright post.

4. The sampling assembly of any of claims 1-3,

and a third accommodating groove is formed in one side, away from the fixed upright post, of the sample frame, and an expansion piece is arranged in the third accommodating groove.

5. The sampling assembly of claim 1,

the sample rack comprises a sample mark, and the sample mark is arranged corresponding to the fixed upright post.

6. The sampling assembly of claim 1, wherein the sample rack is provided with an identification code.

7. The sampling assembly of claim 1, wherein an outer sidewall of the sampling tube is provided with a support portion through which the sampling tube is fixed to the outer housing, and a gap is formed between the sampling tube and the outer housing.

8. The sampling assembly of claim 7, wherein the sampling tube has an internal diameter of between 2mm and 5 mm.

9. A sample analyzer comprising the sampling assembly of any one of claims 1-8 and a detection assembly, the detection assembly being provided with a sample introduction zone, the sampling assembly being adapted to introduce a sample into the sample introduction zone such that the detection assembly detects a sample in the sampling tube.

10. The sample analyzer of claim 9 including a centrifuge assembly for centrifuging a sample from the sampling tube.