CN218710343U

CN218710343U - Novel gene sequencer

Info

Publication number: CN218710343U
Application number: CN202222997535.3U
Authority: CN
Inventors: 陈佳; 巫佩容; 龙健灵
Original assignee: Guangzhou Shengan Medical Laboratory Co ltd
Current assignee: Guangzhou Shengan Medical Laboratory Co ltd
Priority date: 2022-11-10
Filing date: 2022-11-10
Publication date: 2023-03-24
Anticipated expiration: 2032-11-10

Abstract

The utility model provides a novel gene sequencer, include: organism, slewing mechanism, placement mechanism and moving mechanism, the cavity has been seted up to the inside of organism, just the opening has been seted up to the side of organism, the opening with the cavity intercommunication, be provided with a body on the organism, door body movable cover closes the opening, slewing mechanism placement mechanism with moving mechanism all sets up in the cavity, moving mechanism is used for control placement mechanism, placement mechanism activity is located slewing mechanism's below, be provided with the tool to lock on the organism, be provided with the lock seat on the door body, the tool to lock with lock seat swing joint. Use this novel gene sequencer, can avoid the problem that the door body was opened in the experimentation well, safeguard measure is good, need not stretch the instrument the inside and take and deposit moreover when the liquid medicine is being changed to needs, ensures the security of experimentation well, and has improved holistic experimental efficiency.

Description

Novel gene sequencer

Technical Field

The utility model relates to a gene sequencer technical field especially relates to a novel gene sequencer.

Background

The gene sequencer is a professional instrument used for detecting gene sequences, a professional chip is generally used as a carrier for the gene sequencer, then gene molecule liquid medicine to be detected is placed on the chip, the special liquid medicine flows through the chip, the gene sequencer and the chip react to emit specific light, and information of the light can be detected through a special light detection module, so that the gene sequences can be obtained.

At present common gene sequencer simple structure, during the use, need open the hatch door of instrument earlier, will wait to detect the inside that the object was placed the instrument again, however the hatch door does not have fine safeguard measure, also can be opened at instrument during operation, and when using, need stretch the inside and take and deposit in addition, influences holistic experimental efficiency.

SUMMERY OF THE UTILITY MODEL

In order to solve the above problem, the utility model adopts the following technical scheme: a novel gene sequencer comprising: the device comprises a machine body, a rotating mechanism, a placing mechanism and a moving mechanism;

the utility model discloses a storage device, including organism, placing mechanism, moving mechanism, door body, the cavity has been seted up to the inside of organism, just the opening has been seted up to the side of organism, the opening with the cavity intercommunication, be provided with a body on the organism, door body movable cover closes the opening, the rotating mechanism placing mechanism with the moving mechanism all sets up in the cavity, the moving mechanism is used for control placing mechanism, placing mechanism activity is located rotating mechanism's below, be provided with the tool to lock on the organism, be provided with the lock seat on the door body, the tool to lock with lock seat swing joint.

Furthermore, a placing opening is formed in the top of the machine body, a cover body is arranged on the machine body, the cover body is movably covered on the placing opening, and the placing opening is communicated with the cavity.

Further, slewing mechanism includes install bin, first rotating disk, second rotating disk, first rotation motor and second rotation motor, be provided with the mounting bracket in the install bin, first rotation motor with the second rotate the motor all set up in on the mounting bracket, first rotation motor's output shaft with first rotating disk is connected, the second rotate the output shaft of motor with the second rotating disk is connected.

Furthermore, a plurality of first mounting holes are formed in the first rotating disc, a plurality of injectors are arranged on the first rotating disc, each injector is connected with a material storage bottle, and each injector is mounted in one first mounting hole.

Further, a plurality of the syringes are detachably connected with the first rotating disc.

Furthermore, a plurality of second mounting holes are formed in the second rotating disc, a plurality of guide pipes are arranged on the second rotating disc, and each guide pipe is mounted in one of the second mounting holes.

Further, the mounting rack is detachably connected with the mounting box.

Further, the placing mechanism comprises a placing box, a placing seat, a baffle and a detection module, the placing box is provided with a placing groove, the placing seat is arranged in the placing groove, the baffle is movably sealed with the placing groove, the placing seat is used for placing a detection plate, and the detection module is used for detecting the detection plate.

Furthermore, the placing seat is movably positioned below the flow guide pipe.

Further, the moving mechanism comprises a driving motor, a conveying belt and a driving rod, the driving motor is arranged in the cavity, a fixing rod is arranged in the cavity, the conveying belt is rotatably arranged on the fixing rod, the output shaft of the driving motor is connected with the conveying belt, the driving rod is arranged on the conveying belt, and the placing box is arranged on the driving rod.

The utility model has the advantages that: use this novel gene sequencer, can avoid the problem that the door body was opened in the experimentation well, safeguard measure is good, need not stretch the instrument the inside and take and deposit moreover when the liquid medicine is being changed to needs, ensures the security of experimentation well, and has improved holistic experimental efficiency.

Drawings

The accompanying drawings further illustrate the present invention, but the embodiments in the drawings do not constitute any limitation to the present invention.

FIG. 1 is a schematic diagram of an embodiment of a novel gene sequencer;

FIG. 2 is a schematic diagram of an internal structure of a novel gene sequencer according to an embodiment;

FIG. 3 is a schematic diagram showing the internal structure of a novel gene sequencer according to another embodiment;

FIG. 4 is a schematic view of an embodiment of a first rotary plate in one direction;

fig. 5 is a schematic view of an orientation of the second rotating disk according to an embodiment.

Detailed Description

The following will combine the drawings of the embodiments of the present invention to further describe the technical solution of the present invention, and the present invention is not limited to the following specific embodiments. It should be noted that, in the present invention, the embodiments and features of the embodiments may be combined with each other without conflict.

As shown in fig. 1 to 5, a novel gene sequencer includes: organism 100, slewing mechanism, placement mechanism and moving mechanism, cavity 110 has been seted up to organism 100's inside, just the opening has been seted up to organism 100's side, the opening with cavity 110 intercommunication, be provided with a body 120 on the organism 100, the movable cover of a body 120 closes the opening, slewing mechanism placement mechanism with moving mechanism all sets up in the cavity 110, moving mechanism is used for control placement mechanism, placement mechanism activity is located slewing mechanism's below, be provided with tool to lock 121 on the organism 100, be provided with lock seat 101 on the body 120, tool to lock 121 with lock seat 101 swing joint.

Specifically, a placing opening is formed in the top of the machine body 100, a cover body 130 is arranged on the machine body 100, the placing opening is movably covered by the cover body 130, and the placing opening is communicated with the cavity 110. The slewing mechanism includes installation box 210, first carousel 220, second carousel 230, first rotating motor 240 and second rotating motor 250, be provided with mounting bracket 211 in the installation box 210, first rotating motor 240 with second rotating motor 250 all set up in on the mounting bracket 211, first rotating motor 240's output shaft with first carousel 220 is connected, second rotating motor 250's output shaft with second carousel 230 is connected. A plurality of first mounting holes 221 are formed in the first rotating disc 220, a plurality of syringes 500 are arranged on the first rotating disc 220, each syringe 500 is connected with a material storage bottle 600, and each syringe 500 is mounted in one of the first mounting holes 221. A plurality of the syringes 500 are detachably coupled to the first rotary plate 220. A plurality of second mounting holes 231 are formed in the second rotating disk 230, a plurality of flow guide tubes 700 are arranged on the second rotating disk 230, and each flow guide tube 700 is mounted in one second mounting hole 231. The mounting bracket 211 is detachably connected to the mounting box 210. Further, the placing mechanism comprises a placing box 310, a placing seat 320, a baffle 330 and a detecting module 340, wherein the placing box 310 is provided with a placing groove 311, the placing seat 320 is arranged in the placing groove 311, the baffle 330 movably seals the placing groove 311, the placing seat 320 is used for placing a detecting plate 350, and the detecting module 340 is used for detecting the detecting plate 350. The placing seat 320 is movably located below the duct 700. The moving mechanism comprises a driving motor 410, a conveyor belt 420 and a driving rod 430, wherein the driving motor 410 is arranged in the cavity 110, a fixing rod 440 is arranged in the cavity 110, the conveyor belt 420 is rotatably arranged on the fixing rod 440, an output shaft of the driving motor 410 is connected with the conveyor belt 420, the driving rod 430 is arranged on the conveyor belt 420, and the placing box 310 is arranged on the driving rod 430.

It is worth mentioning that the gene sequencer also comprises a control system, the rotating mechanism, the placing mechanism and the moving mechanism are all connected with the control system through electric signals, and further, the control system is a PLC control system, namely, the rotating mechanism, the placing mechanism and the moving mechanism are controlled through a program formulated through programming.

That is, in the initial state, the cover 130 is opened, the mounting frame 211 in the mounting box 210 is taken out, and then the syringe 500 is mounted in each first mounting hole 221, it is worth mentioning that the reaction solution contained in the storage bottle 600 connected to each syringe 500 is different, and each syringe 500 is controlled by the control system. After the syringe 500 is mounted, each of the fluid guide tubes 700 is mounted in one of the second mounting holes 231. It is worth mentioning that how to mount the injector 500 in the first mounting hole 221 or how to mount the delivery tube 700 in the second mounting hole 231 can be implemented by the prior art and fixed, for example, by a threaded connection, for example, by a snap connection, which is not described redundantly in this embodiment. That is, after the syringe 500 and the delivery tube 700 are placed, the mounting bracket 211 is returned to the mounting case 210. The entire mounting box 210 is then placed back into the cavity 110 of the housing 100 and covered with the cover 130. Further, the baffle 330 in the initial state seals the placing groove 311, that is, it is well ensured that the detection plate 350 on the placing base 320 is not contaminated by the external environment.

When the detection plate is used, a worker opens the door body 120 and pushes the baffle plate 330 open, so that the baffle plate 330 does not seal the placing groove 311, then the gene liquid medicine to be detected is injected onto the detection plate 350, then after the door body 120 is closed, the injector 500 positioned above the detection plate 350 is started, the injector 500 injects the reaction liquid medicine in the corresponding storage bottle 600 onto the detection plate 350 through the corresponding guide pipe 700, and after a period of reaction, the detection plate 350 is detected through the detection module 340, so that the base sequence of the gene fragment is obtained. Further, because the lock 121 is arranged on the machine body 100, and the lock seat 101 is arranged on the door 120, when an experiment is started, the lock 121 is locked on the lock seat 101, so that the problem that the whole experiment effect is influenced by opening the door 120 in the experiment process can be avoided.

It should be noted that, when another reaction liquid medicine needs to be used and a new flow guide tube 700 needs to be used for drainage injection, the control system is used to start the first rotating motor 240 and the second rotating motor 250, the first rotating motor 240 drives the first rotating disk 220 to rotate, the second rotating motor 250 drives the second rotating disk 230 to rotate, that is, the injector 500 and the material storage bottle 600 containing the corresponding reaction liquid medicine needs to be used are rotated above the detection plate 350, and the corresponding new flow guide tube 700 is also rotated above the detection plate 350. That is, if it is not necessary to use a new guide tube 700, it is only necessary to activate the first rotary plate 220, that is, to rotate the syringe 500 and the storage bottle 600 containing the reaction solution corresponding to the use to be performed above the sensing plate 350. Therefore, the activation of the first and second rotating

motors

240 and 250 is controlled according to specific requirements, and is not described redundantly in this embodiment.

That is to say, use this novel gene sequencer, can avoid the problem that the door body 120 was opened in the experimentation well, safeguard measure is good, when the liquid medicine needs to be changed, need not stretch the instrument the inside and take and deposit moreover, ensures the security of experimentation well, and has improved holistic experimental efficiency.

In the above embodiment, by using the driving motor 410, the output shaft of the driving motor 410 rotates to drive the conveying belt 420 to rotate, that is, after the detection is completed, the door 120 is opened, and then the driving motor 410 is started, so that the conveying belt 420 starts to convey, and further the driving rod 430 is driven to move, that is, the driving rod 430 drives the whole placing box 310 to move to the outside of the machine body 100, and finally moves out of the cavity 110. That is to say, through this mode, the staff can directly take out pick-up plate 350 outside organism 100, then replaces new pick-up plate 350, need not stretch into inside and take and deposit, improves holistic experimental efficiency.

In the above embodiment, each syringe 500 is controlled by the control system, and each syringe 500 is a syringe 500 without a piston, that is, when an injection is required, the control system activates the connection pump by connecting a connection pump to each syringe 500, and the connection pump pumps the reaction liquid medicine in the storage bottle 600 into the syringe 500 and leads the reaction liquid medicine from the syringe to the guide tube 700.

As described above, the above embodiments are not limiting embodiments of the present invention, and modifications or equivalent variations made by those skilled in the art based on the substance of the present invention are within the technical scope of the present invention.

Claims

1. A novel gene sequencer, comprising: the device comprises a machine body, a rotating mechanism, a placing mechanism and a moving mechanism;

2. The novel gene sequencer according to claim 1, wherein: the top of the machine body is provided with a placing opening, the machine body is provided with a cover body, the cover body movably covers the placing opening, and the placing opening is communicated with the cavity.

3. The novel gene sequencer of claim 2, wherein: the slewing mechanism includes installation box, first rotating disc, second rotating disc, first rotation motor and second rotation motor, be provided with the mounting bracket in the installation box, first rotation motor with the second rotate the motor all set up in on the mounting bracket, first rotation motor's output shaft with first rotating disc is connected, the second rotate the motor the output shaft with the second rotating disc is connected.

4. The novel gene sequencer of claim 3, wherein: a plurality of first mounting holes are formed in the first rotating disc, a plurality of injectors are arranged on the first rotating disc, each injector is connected with a material storage bottle, and each injector is mounted in one first mounting hole.

5. The novel gene sequencer according to claim 4, wherein: and the injectors are detachably connected with the first rotating disc.

6. The novel gene sequencer of claim 5, wherein: a plurality of second mounting holes are formed in the second rotating disc, a plurality of guide pipes are arranged on the second rotating disc, and each guide pipe is mounted in one second mounting hole.

7. The novel gene sequencer according to claim 6, wherein: the mounting bracket with the install bin can dismantle the connection.

8. The novel gene sequencer according to claim 7, wherein: the placing mechanism comprises a placing box, a placing seat, a baffle and a detection module, wherein the placing box is provided with a placing groove, the placing seat is arranged in the placing groove, the baffle is movably sealed with the placing groove, the placing seat is used for placing a detection plate, and the detection module is used for detecting the detection plate.

9. The novel gene sequencer of claim 8, wherein: the placing seat is movably positioned below the flow guide pipe.

10. The novel gene sequencer of claim 9, wherein: the moving mechanism comprises a driving motor, a conveying belt and a driving rod, the driving motor is arranged in the cavity, a fixed rod is arranged in the cavity, the conveying belt is rotatably arranged on the fixed rod, the output shaft of the driving motor is connected with the conveying belt, the driving rod is arranged on the conveying belt, and the placing box is arranged on the driving rod.