CN218691121U - Coating machine is used in production of transdermal patch - Google Patents

Coating machine is used in production of transdermal patch Download PDF

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Publication number
CN218691121U
CN218691121U CN202223036298.0U CN202223036298U CN218691121U CN 218691121 U CN218691121 U CN 218691121U CN 202223036298 U CN202223036298 U CN 202223036298U CN 218691121 U CN218691121 U CN 218691121U
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China
Prior art keywords
frame
cutter
coating machine
mounting
transdermal patch
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CN202223036298.0U
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Chinese (zh)
Inventor
海燕
王琦芳
李肖青
李阳
王海燕
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Guoyao Ruifulai Pharmaceutical Co ltd
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China Pharmaceutical Group Shanxi Ruifulai Pharmaceutical Co ltd
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P70/00Climate change mitigation technologies in the production process for final industrial or consumer products
    • Y02P70/10Greenhouse gas [GHG] capture, material saving, heat recovery or other energy efficient measures, e.g. motor control, characterised by manufacturing processes, e.g. for rolling metal or metal working

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Abstract

The application relates to a coating machine for producing transdermal patches, which relates to the field of external patch manufacturing equipment and comprises a coater support, wherein a conveyor belt is arranged on the coater support, an installation frame is arranged above the conveyor belt and fixedly arranged on the coater support, a cutter frame is arranged on the installation frame, and a scraper is arranged on the cutter frame; a plurality of uniformly distributed mounting holes are symmetrically formed in the mounting frame, clamping rods penetrate through the mounting holes, and the clamping rods are fixedly mounted on the tool rest; equal fixed mounting has the sleeve in the mounting hole, wears to be equipped with the loop bar in the sleeve, and telescopic one end fixed mounting is kept away from to the loop bar has the push pedal, and the cover is equipped with first reset spring on the loop bar, and first reset spring one end fixed connection is on the sleeve, and first reset spring other end fixed connection has the connecting rod that two symmetries set up in the push pedal, and the articulated joint of the one end of keeping away from the push pedal of two connecting rods has the joint piece. This application has swift installation cutter, quick adjustment cutter angle and vertical height's effect.

Description

Coating machine for transdermal patch production
Technical Field
The application relates to the field of external patch preparation equipment, in particular to a coating machine for producing a transdermal patch.
Background
The patch means a sheet-like preparation which can be adhered to the skin and the drug can produce systemic or local effect, and comprises a backing layer, a drug storage layer with (or without) a controlled release membrane, an adhesive layer and a protective layer which needs to be removed before use. The patch can be applied to the whole skin surface, or to a diseased or incomplete skin surface. Among them, a patch that is applied to the surface of the skin intact and can deliver a drug into the blood circulation system through the skin is called a transdermal patch. Modern transdermal patches are patches or patch drugs that are absorbed through the skin and rapidly and durably enter the body through a controlled release mechanism in a dosage required by the condition.
The preparation method of the patch provided by the related art comprises a basal layer coating mechanism, wherein the uncoated part is coated by a method such as scraper transfer coating or extrusion coating, and the type, angle and height of a scraper need to be adjusted according to different process requirements in the coating process.
In view of the above-mentioned related art, the inventors consider that the coating machine for transdermal patch production at the present stage has problems that the cutter mounting step is complicated, and the angle and height of the blade are not easily adjusted during use.
SUMMERY OF THE UTILITY MODEL
In order to simplify the cutter installation step, quick adjustment cutter angle and vertical height, this application provides a coating machine for transdermal patch production.
The application provides a coating machine is used in transdermal patch production adopts following technical scheme:
a coating machine for producing transdermal patches comprises an applicator support, wherein a conveyor belt is arranged on the applicator support, an installation frame is arranged above the conveyor belt and fixedly arranged on the applicator support, a cutter frame is arranged on the installation frame, and a scraper is arranged on the cutter frame;
a plurality of mounting holes which are uniformly distributed are symmetrically formed in the mounting frame, clamping rods penetrate through the mounting holes, and the clamping rods are fixedly mounted on the tool rest;
several equal fixed mounting has the sleeve in the mounting hole, wear to be equipped with the loop bar in the sleeve, telescopic one end fixed mounting is kept away from to the loop bar has the push pedal, the cover is equipped with first reset spring on the loop bar, first reset spring one end fixed connection is on the sleeve, telescopic one end fixed connection is kept away from to first reset spring in the push pedal, it has the connecting rod that two symmetries set up, two to articulate in the push pedal the articulated joint of one end that the push pedal was kept away from to the connecting rod has the joint piece.
Through adopting above-mentioned technical scheme, install the scraper on the cutter frame, install the cutter frame on the coating apparatus through the mounting bracket simultaneously, later remove the joint piece that drives the symmetry setting through the push pedal and remove to the direction that is close to each other, press from both sides the cutter frame tightly, guarantee that cutter frame steady mounting is on the mounting bracket, improve a transdermal patch production with the stable in structure of coating machine, simplify cutter installation procedure simultaneously, conveniently change and install the scraper.
Optionally, the mounting hole is internally and fixedly provided with two first limiting rods symmetrically arranged, and each first limiting rod is provided with a clamping block in a sliding mode, and the clamping blocks are sleeved on the first limiting rods.
Through adopting above-mentioned technical scheme, set up first gag lever post and establish the joint piece cover on first gag lever post, inject the moving direction of joint piece, guarantee that the push pedal removes and can normally drive two joint pieces and remove to the direction that is close to each other or keeps away from each other, guarantee that the transmission of joint piece is stable.
Optionally, the tool rest comprises a main body frame, a plurality of clamping rods are fixedly connected to the main body frame, clamping grooves are symmetrically formed in the clamping rods, and clamping blocks are clamped in the clamping grooves.
Through adopting above-mentioned technical scheme, set up the joint groove on the joint pole, joint piece joint is in the joint inslot, and the joint groove carries out the position to the joint piece and prescribes a limit to, improves the installation stability of cutter frame.
Optionally, a first rotating shaft penetrates through the main body frame, the first rotating shaft is rotatably connected to the main body frame, a first driving bevel gear is fixedly installed at one end of the first rotating shaft, the first driving bevel gear is connected with a first driven bevel gear in a meshed manner, the first driven bevel gear is fixedly sleeved on a second rotating shaft, second driving bevel gears are fixedly sleeved at two ends of the second rotating shaft, the two driving bevel gears are connected with a second driven bevel gear in a meshed manner, the second driven bevel gear is fixedly sleeved on a screw, and the screw is rotatably installed on the main body frame;
the two screw rods are all in threaded connection with moving blocks, the two moving blocks are rotatably mounted on one sides close to each other, and scrapers are fixedly mounted between the two cutter fixing blocks.
By adopting the technical scheme, through rotating the first rotating shaft, the first rotating shaft rotates to drive the first driving bevel gear to rotate, the first driving bevel gear rotates to drive the first driven bevel gear to rotate, the first driven bevel gear rotates to drive the second rotating shaft to rotate, the second rotating shaft rotates to drive the two second driving bevel gears to rotate, the two second driving bevel gears rotate to drive the two second driven bevel gears to rotate, the two second driven bevel gears rotate to drive the screw rod to rotate, the screw rod rotates while driving the moving block in threaded connection with the screw rod to move in the vertical direction, and therefore the vertical height of the cutter can be quickly adjusted.
Optionally, two second limiting rods symmetrically arranged are fixedly mounted on one side, close to each other, of each of the two moving blocks, a second return spring is sleeved on each second limiting rod, one end of each second return spring is fixedly connected to the corresponding moving block, one end, far away from the corresponding moving block, of each second return spring is fixedly connected to a fixture block, the fixture block is sleeved on the corresponding second limiting rod, and the fixture block is slidably mounted on the corresponding second limiting rod.
Optionally, a plurality of clamping grooves which are uniformly distributed are formed on the periphery of each of the two cutter fixing blocks;
the clamping blocks are clamped in the two clamping grooves which are symmetrically arranged.
Through adopting above-mentioned technical scheme, through rotating the cutter fixed block to through the fixture block joint in the draw-in groove, make cutter fixed block angle fixed, and then adjust the scraper angle, realize the quick adjustment to the scraper angle.
Optionally, the second rotating shaft penetrates through the plurality of limiting plates, and the plurality of limiting plates are uniformly and fixedly mounted on the main body frame.
Through adopting above-mentioned technical scheme, set up the limiting plate and inject second pivot position, guarantee that the second pivot can normally rotate under first driven bevel gear's drive, it is stable to improve the transmission of a transdermal patch production with coating machine.
Optionally, the screw shafts are opposite in rotation direction.
By adopting the technical scheme, the rotating directions of the two screws are opposite, and the moving blocks can synchronously move on the two screws while the two screws rotate.
In summary, the present application includes at least one of the following beneficial technical effects:
1. the scraper is arranged on the cutter frame, the cutter frame is arranged on the coater through the mounting frame, the symmetrically arranged clamping blocks are driven to move towards the mutually approaching direction through the movement of the push plate, the cutter frame is clamped, the cutter frame is ensured to be stably arranged on the mounting frame, the structure stability of the coater for producing the transdermal patches is improved, the cutter mounting step is simplified, and the scraper is convenient to replace and mount;
2. by rotating the first rotating shaft, the first rotating shaft rotates to drive the first driving bevel gear to rotate, the first driving bevel gear rotates to drive the first driven bevel gear to rotate, the first driven bevel gear rotates to drive the second rotating shaft to rotate, the second rotating shaft rotates to drive the two second driving bevel gears to rotate, the two second driving bevel gears rotate to drive the two second driven bevel gears to rotate, the two second driven bevel gears rotate to drive the screw to rotate, and the screw rotates to simultaneously drive the moving block in threaded connection with the screw to move in the vertical direction, so that the vertical height of the cutter can be quickly adjusted;
3. through rotating the cutter fixed block to through the fixture block joint in the draw-in groove, make cutter fixed block angle fixed, and then adjust the scraper angle, realize the quick adjustment to the scraper angle.
Drawings
FIG. 1 is a schematic structural diagram of an embodiment of the present application;
FIG. 2 is a schematic view of the internal structure of a mounting hole according to an embodiment of the present application;
FIG. 3 is a schematic view of a tool holder configuration according to an embodiment of the present application;
FIG. 4 is an enlarged view at A of an embodiment of the present application;
fig. 5 is a schematic structural diagram of a moving block according to an embodiment of the present application.
Description of reference numerals: 1. an applicator support; 2. a conveyor belt; 3. a mounting frame; 31. mounting holes; 32. a sleeve; 33. a loop bar; 34. a first return spring; 35. pushing a plate; 36. a connecting rod; 37. a clamping block; 38. a first limit rod; 4. a tool holder; 41. a clamping and connecting rod; 411. a clamping groove; 42. a main body frame; 43. a first rotating shaft; 431. a first drive bevel gear; 432. a first driven bevel gear; 44. a second rotating shaft; 441. a second drive bevel gear; 442. a second driven bevel gear; 443. a limiting plate; 45. a screw; 46. a moving block; 47. a cutter fixing block; 471. a card slot; 48. a clamping block; 49. a second return spring; 410. a second limiting rod; 5. and (4) scraping the blade.
Detailed Description
The present application is described in further detail below with reference to figures 1-5.
The embodiment of the application discloses a coating machine is used in transdermal patch production.
Referring to fig. 1, the coating machine for producing the transdermal patch comprises an applicator support 1, a conveyor belt 2 is installed on the applicator support 1, an installation frame 3 is arranged above the conveyor belt 2, the installation frame 3 is fixedly installed on the applicator support 1, a cutter frame 4 is installed on the installation frame 3, and a scraper 5 is installed on the cutter frame 4.
Use a coating machine for transdermal patch production to add man-hour to transdermal patch, at first install cutter frame 4 on mounting bracket 3, adjust 5 angles of scraper and 5 vertical height of scraper through cutter frame 4 simultaneously, guarantee that scraper 5 accords with the technological requirement to transdermal patch's coating, later arrange the transdermal patch of treating processing in on conveyer belt 2, conveyer belt 2 work conveys the transdermal patch of treating processing to scraper 5 department, scraper 5 coats transdermal patch, the completion is to transdermal patch's processing work.
Referring to fig. 1 and 2, mounting bracket 3 includes several evenly distributed's mounting hole 31, two are no less than to mounting hole 31 quantity, equal fixed mounting has sleeve 32 in the several mounting hole 31, sleeve 32 axis is the same with mounting hole 31 axis, wear to be equipped with loop bar 33 in the sleeve 32, loop bar 33 and sleeve 32 sliding connection, loop bar 33 week side cover is equipped with first reset spring 34, first reset spring 34 one end and sleeve 32 fixed connection, the first reset spring 34 other end and push pedal 35 fixed connection, push pedal 35 fixed connection is in the one end that sleeve 33 kept away from sleeve 32, the last articulated connecting rod 36 that has two symmetries to set up of push pedal 35 that has of push pedal 35, two connecting rod 36 one end of keeping away from push pedal 35 all articulates there is joint piece 37, two joint piece 37 are established respectively on two first gag lever posts 38, joint piece 37 and first gag lever post 38 sliding connection, two first gag lever post 38 symmetry fixed mounting are in mounting hole 31.
When installing tool rest 4 on mounting bracket 3, tool rest 4 and push pedal 35 butt and promote push pedal 35 to the one end that is close to sleeve 32 and move, drive loop bar 33 and slide in sleeve 32 when push pedal 35 moves, and first reset spring 34 atress compression is under the effect of push pedal 35 simultaneously. The push plate 35 drives the two clamping blocks 37 which are symmetrically arranged to move towards the direction close to each other through the connecting rod 36 while moving, so that the tool rack 4 is clamped and fixed. When needing to dismantle tool carrier 4, first reset spring 34 resumes length, and then promotes push plate 35 and remove to the direction of keeping away from sleeve 32, and push plate 35 drives the joint piece 37 of two symmetry settings through connecting rod 36 when removing and removes to the direction of keeping away from each other, conveniently dismantles tool carrier 4.
Referring to fig. 2 and 3, the tool rack 4 includes a main body frame 42 fixedly installed with a plurality of clamping rods 41, the plurality of clamping rods 41 are uniformly installed on the main body frame 42, the plurality of clamping rods 41 are correspondingly installed in the installation holes 31, clamping grooves 411 are symmetrically formed in the plurality of clamping rods 41, the shapes of the clamping grooves 411 are the same as those of the clamping blocks 37, and the clamping blocks 37 are embedded in the clamping grooves 411.
When installing cutter frame 4, through installing joint pole 41 in mounting hole 31, and with joint pole 41 one end and push pedal 35 butt, joint pole 41 promotes push pedal 35 and removes to the direction that is close to sleeve 32, and then makes the joint piece 37 of two symmetry settings remove to the direction that is close to each other, joint piece 37 inlays to establish in joint groove 411 simultaneously, makes main part frame 42 fixed mounting on mounting bracket 3, guarantees the structural stability of a transdermal patch production with coating machine.
Referring to fig. 4 and 5, a first rotating shaft 43 is further arranged on the main body frame 42 in a penetrating manner, the first rotating shaft 43 is rotatably connected with the main body frame 42, a first driving bevel gear 431 is fixedly arranged at one end of the first rotating shaft 43, the first driving bevel gear 431 is fixedly sleeved on the first rotating shaft 43, the first driving bevel gear 431 is connected with a first driven bevel gear 432 in a meshing manner, the first driven bevel gear 432 is fixedly sleeved on a second rotating shaft 44, a second rotating shaft 44 is arranged on a plurality of uniformly-arranged limiting plates 443 in a penetrating manner, the second rotating shaft 44 is rotatably connected with the limiting plates 443, the plurality of limiting plates 443 are fixedly arranged on the main body frame 42, two ends of the second rotating shaft 44 are symmetrically and fixedly sleeved with a second driving bevel gear 441, two second driven bevel gears 442 are respectively and fixedly sleeved on the two screw rods 45, the two screw rods 45 are rotatably arranged on the main body frame 42, the two screw rods 45 have opposite thread turning directions, the two screw rods 45 are respectively and are in threaded connection with moving blocks 46, one side, the two sides of the two symmetrically-arranged moving blocks 46 are abutted to the main body frame 42, the side of the two sides of the symmetrically-arranged moving blocks 471, the moving blocks 46 are rotatably arranged close to each other and are provided with a plurality of moving blocks 47, and the even-number of the moving blocks 47 is greater than that of the two moving blocks 47 are uniformly-arranged, and is greater than that of the two moving blocks, and is equal-number of the two moving blocks is greater than that of the two moving blocks 471. Two of the clipping grooves 471 symmetrically arranged in the clipping grooves 471 are clipped with a clipping block 48, one end of the clipping block 48 away from the clipping groove 471 is sleeved on the second limiting rod 410, the clipping block 48 is slidably connected with the second limiting rod 410, one end of the second limiting rod 410 away from the clipping block 48 is fixedly mounted on the moving block 46, a second return spring 49 is sleeved on the second limiting rod 410, one end of the second return spring 49 is fixedly connected with the clipping block 48, and the other end of the second return spring 49 is fixedly connected with the moving block 46. Two ends of the scraper 5 are respectively and fixedly arranged on the two cutter fixing blocks 47.
When the position of the scraper 5 is adjusted by the cutter frame 4, firstly, the first rotating shaft 43 is rotated, the first rotating shaft 43 rotates to drive the first driving bevel gear 431 to rotate, the first driving bevel gear 431 rotates to drive the first driven bevel gear 432 to rotate, the first driven bevel gear 432 rotates to drive the second rotating shaft 44 to rotate, the second rotating shaft 44 rotates to drive the two second driving bevel gears 441 to rotate, the two second driving bevel gears 441 rotate to drive the two second driven bevel gears 442 to rotate, the two second driven bevel gears 442 rotate to drive the screw rod 45 to rotate, the screw rod 45 rotates while driving the moving block 46 in threaded connection with the screw rod 45 to move in the vertical direction, so as to adjust the vertical height of the scraper, meanwhile, the cutter fixing block 47 is clamped in the clamping groove 471 by rotating the cutter fixing block 48, so that the angle of the cutter fixing block 47 is fixed, and the angle of the scraper 5 is adjusted, thereby adjusting the angle of the scraper 5.
The implementation principle of the coating machine for producing the transdermal patch in the embodiment of the application is as follows: install cutter frame 4 on mounting bracket 3 at first, simultaneously through 5 angles of cutter frame 4 adjustment scraper and 5 vertical heights of scraper, guarantee that scraper 5 accords with the technological requirement to the coating of transdermal patch, later will treat the transdermal patch of processing and arrange conveyer belt 2 in, 2 work of conveyer belt will treat the transdermal patch conveying of processing to scraper 5 department, scraper 5 coats transdermal patch, the completion is to the processing work of transdermal patch, realize simplifying cutter installation procedure, quick adjustment cutter angle and vertical height's effect.
The above are preferred embodiments of the present application, and the scope of protection of the present application is not limited thereto, so: all equivalent changes made according to the structure, shape and principle of the present application shall be covered by the protection scope of the present application.

Claims (8)

1. A coating machine for producing transdermal patches is characterized in that: the coating device comprises a coater support (1), wherein a conveyor belt (2) is installed on the coater support (1), an installation frame (3) is arranged above the conveyor belt (2), the installation frame (3) is fixedly installed on the coater support (1), a cutter frame (4) is installed on the installation frame (3), and a scraper (5) is installed on the cutter frame (4);
a plurality of uniformly distributed mounting holes (31) are symmetrically formed in the mounting frame (3), clamping rods (41) penetrate through the mounting holes (31), and the clamping rods (41) are fixedly mounted on the tool rest (4);
several equal fixed mounting has sleeve (32) in mounting hole (31), wear to be equipped with loop bar (33) in sleeve (32), the one end fixed mounting that sleeve (32) were kept away from in loop bar (33) has push pedal (35), the cover is equipped with first reset spring (34) on loop bar (33), first reset spring (34) one end fixed connection is on sleeve (32), the one end fixed connection that sleeve (32) were kept away from in first reset spring (34) is on push pedal (35), it has connecting rod (36) that two symmetries set up, two to articulate on push pedal (35) the articulated joint of the one end that has joint piece (37) that has of push pedal (35) were kept away from in connecting rod (36).
2. The coating machine for producing transdermal patch according to claim 1, characterized in that: several equal fixed mounting has first gag lever post (38) that two symmetries set up in mounting hole (31), two equal slidable mounting has joint piece (37) on first gag lever post (38), joint piece (37) cover is established on first gag lever post (38).
3. The coating machine for producing transdermal patch according to claim 2, characterized in that: cutter frame (4) are including main part frame (42), fixedly connected with several joint pole (41) on main part frame (42), joint groove (411) have been seted up to the symmetry on joint pole (41), joint has joint piece (37) in joint groove (411).
4. A coating machine for the production of transdermal patch according to claim 3, characterized in that: a first rotating shaft (43) penetrates through the main body frame (42), the first rotating shaft (43) is rotatably connected to the main body frame (42), one end of the first rotating shaft (43) is fixedly provided with a first driving bevel gear (431), the first driving bevel gear (431) is connected with a first driven bevel gear (432) in a meshing manner, the first driven bevel gear (432) is fixedly sleeved on a second rotating shaft (44), two ends of the second rotating shaft (44) are fixedly sleeved with second driving bevel gears (441), the two driving bevel gears are respectively connected with a second driven bevel gear (442) in a meshing manner, the second driven bevel gears (442) are fixedly sleeved on a screw rod (45), and the screw rod (45) is rotatably installed on the main body frame (42);
moving blocks (46) are in threaded connection with the two screw rods (45), cutter fixing blocks (47) are rotatably mounted on one sides, close to each other, of the two moving blocks (46), and scrapers (5) are fixedly mounted between the two cutter fixing blocks (47).
5. The coating machine for the production of transdermal patch according to claim 4, characterized in that: two second limiting rods (410) which are symmetrically arranged are fixedly mounted on one side, close to each other, of each of the two moving blocks (46), a second return spring (49) is sleeved on each second limiting rod (410), one end of each second return spring (49) is fixedly connected to each moving block (46), one end, far away from each moving block (46), of each second return spring (49) is fixedly connected to a fixture block (48), each fixture block (48) is sleeved on each second limiting rod (410), and each fixture block (48) is slidably mounted on each second limiting rod (410).
6. The coating machine for transdermal patch production according to claim 5, characterized in that: a plurality of clamping grooves (471) are uniformly distributed on the periphery of each of the two cutter fixing blocks (47);
the clamping blocks (48) are clamped in the two clamping grooves (471) which are symmetrically arranged.
7. The coating machine for transdermal patch production according to claim 4, characterized in that: the second rotating shaft (44) penetrates through the plurality of limiting plates (443), and the plurality of limiting plates (443) are uniformly and fixedly installed on the main body frame (42).
8. The coating machine for transdermal patch production according to claim 4, characterized in that: the rotation directions of the two screws (45) are opposite.
CN202223036298.0U 2022-11-15 2022-11-15 Coating machine is used in production of transdermal patch Active CN218691121U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202223036298.0U CN218691121U (en) 2022-11-15 2022-11-15 Coating machine is used in production of transdermal patch

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202223036298.0U CN218691121U (en) 2022-11-15 2022-11-15 Coating machine is used in production of transdermal patch

Publications (1)

Publication Number Publication Date
CN218691121U true CN218691121U (en) 2023-03-24

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ID=85619570

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202223036298.0U Active CN218691121U (en) 2022-11-15 2022-11-15 Coating machine is used in production of transdermal patch

Country Status (1)

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CN (1) CN218691121U (en)

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GR01 Patent grant
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CP03 Change of name, title or address

Address after: No. 19, Medical Park, Tanghuai Industrial Park, Shanxi Transformation Comprehensive Reform Demonstration Zone, Taiyuan City, Shanxi Province 030082

Patentee after: Guoyao Ruifulai Pharmaceutical Co.,Ltd.

Address before: 030082 No. 19, medicine Park, Taiyuan Economic and Technological Development Zone, Taiyuan City, Shanxi Province

Patentee before: China Pharmaceutical Group Shanxi ruifulai Pharmaceutical Co.,Ltd.

CP03 Change of name, title or address