CN218674703U - Substrate missing adding detection device for full-automatic optical immunoassay analyzer - Google Patents
Substrate missing adding detection device for full-automatic optical immunoassay analyzer Download PDFInfo
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- CN218674703U CN218674703U CN202222878458.XU CN202222878458U CN218674703U CN 218674703 U CN218674703 U CN 218674703U CN 202222878458 U CN202222878458 U CN 202222878458U CN 218674703 U CN218674703 U CN 218674703U
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Abstract
The utility model discloses a substrate leakage detection device for a full-automatic optical immunoassay analyzer, which comprises a fixed frame and a light-shading box arranged on the fixed frame, wherein a light-transmitting liquid path pipe is vertically arranged in the light-shading box, the upper and lower pipe orifices of the light-transmitting liquid path pipe are respectively communicated with the upper light-shading liquid path pipe and the lower light-shading liquid path pipe through pipe joints, and the upper and lower light-shading liquid path pipes respectively vertically extend out of the light-shading box; a photoelectric bubble sensor for detecting bubbles in the light-transmitting liquid path pipe is arranged on the light-transmitting liquid path pipe, and a signal line and a power line of the photoelectric bubble sensor hermetically penetrate through the outside of the light-avoiding box and are connected with the control and data processing unit; and the control and data processing unit is used for providing working voltage for the photoelectric bubble sensor, receiving a detection signal of the photoelectric bubble sensor, analyzing and processing the detection signal and judging whether the substrate is added in a missing manner or not during sample detection. The utility model provides a false retrieval problem that ultrasonic wave bubble sensor brought, the rate of accuracy is high, has improved work efficiency.
Description
Technical Field
The utility model relates to a full-automatic optical immunoassay appearance especially relates to a substrate that is used for full-automatic optical immunoassay appearance leaks to add detection device.
Background
The method for detecting the liquid pipeline by the bubble detection technology is widely applied to external diagnostic instruments such as a full-automatic optical immunity analyzer, a biochemical analyzer and the like. When the analyzer is used for sample detection, a catalyst, commonly called "substrate", is usually added to the sample for sample analysis and detection. However, because the substrate used by the analyzer belongs to a special chemical agent and has the characteristic that the natural illumination for a long time can change the characteristics of the substrate and influence the sample detection result of the analyzer, the substrate pipeline on the analyzer generally adopts a black opaque liquid pipeline. Aiming at the characteristics of a substrate and a liquid path pipe, the existing substrate bubble detection method adopts an ultrasonic sensor, and utilizes the principle that the ultrasonic wave passes through the air bubble or the energy attenuation difference of the liquid to judge whether the liquid or the air bubble is in a liquid path pipe, but because the ultrasonic bubble sensor is sensitive, the anti-interference capability is poor, the noise ratio is low, the requirements on the self state of the liquid path pipe and the installation of the liquid path pipe are high, and meanwhile, the detection result of the ultrasonic bubble sensor can be influenced by scratches and deformation generated in the installation process of the liquid path pipe, so that the ultrasonic sensor can not accurately distinguish whether the liquid or the air bubble, and the false detection is easily caused. The other method is that an instrument operator needs to detect abnormal data through a sample on the software of the client side of the analyzer to analyze whether the quantity of the substrate required by sample detection is leaked or not; because the daily sample detection data of the analyzer is huge, the operator of the analyzer needs to spend a lot of working time to analyze the abnormal data, the workload is large, the efficiency is low, and human errors are easy to occur.
Disclosure of Invention
An object of the utility model is to provide a substrate leaks adds detection device for full-automatic optical immunoassay appearance to improve work efficiency and detection rate of accuracy.
In order to achieve the purpose, the invention adopts the following technical scheme:
the substrate leakage detection device for the full-automatic optical immunoassay analyzer comprises a fixing frame and a light shielding box arranged on the fixing frame, wherein a light transmitting liquid pipeline is vertically arranged in the light shielding box, the upper and lower pipe openings of the light transmitting liquid pipeline are respectively communicated with the upper and lower light shielding liquid pipelines through pipe joints, and the upper and lower light shielding liquid pipelines respectively vertically extend out of the light shielding box; the light-transmitting liquid path pipe is provided with a photoelectric bubble sensor for detecting bubbles in the light-transmitting liquid path pipe, and a signal line and a power line of the photoelectric bubble sensor hermetically penetrate through the outside of the light-shielding box and are connected with the control and data processing unit;
and the control and data processing unit is used for providing working voltage for the photoelectric bubble sensor, receiving a detection signal of the photoelectric bubble sensor, analyzing and processing the detection signal and judging whether the substrate is added in a missing manner or not during sample detection.
Optionally, the control and data processing unit comprises
The single chip microcomputer is used for controlling substrate missing adding detection and processing data;
the photoelectric bubble sensor working voltage control circuit is used for receiving a control signal sent by the singlechip and realizing the connection and the disconnection of the working voltage of the photoelectric bubble sensor;
furthermore, the working voltage control circuit of the photoelectric bubble sensor comprises a triode Q1, the base electrode of the triode Q1 is connected with the control signal output end of the single chip microcomputer through a current-limiting resistor R4, the collector electrode of the triode Q1 is connected with the power source negative electrode interface of the photoelectric bubble sensor, the power source positive electrode interface of the photoelectric bubble sensor is connected with the 5V power source output end of the power source module, the emitting electrode of the triode Q1 is grounded, and the high potential end of the current-limiting resistor R4 is grounded through a pull-down resistor R5;
the detection signal processing circuit is used for converting the detection signal output by the photoelectric bubble sensor into an input signal suitable for the singlechip;
furthermore, the detection signal processing circuit comprises a series circuit consisting of resistors R1 and R2, an integrated operational amplifier U1 and a filter capacitor C1; the non-inverting input end of the integrated operational amplifier U1 is connected with the detection signal output end of the photoelectric bubble sensor through the resistor R1, the inverting input end of the integrated operational amplifier U1 is connected with the output end of the integrated operational amplifier U1, and the output end of the integrated operational amplifier U1 is connected with the signal input end of the single chip microcomputer through a resistor R3 and is grounded through the filter capacitor C1;
the CAN communication module is used for uploading a substrate missing adding detection result sent by the singlechip to an upper computer of the analyzer;
and the power module is used for providing working voltage for the photoelectric bubble sensor, the detection signal processing circuit, the single chip microcomputer and the CAN communication module.
The utility model discloses a whether the accurate detection that the substrate leaks to add of analysis appearance when the sample detection, the false retrieval problem of having solved ultrasonic wave bubble sensor and bringing, the rate of accuracy is high. Meanwhile, the workload of analyzing the substrate missing according to the sample test result by the existing manpower is greatly reduced, and the working efficiency is improved.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
Fig. 2 is a schematic circuit diagram of the control and data processing unit according to the present invention.
Detailed Description
The embodiments of the present invention will be described in detail with reference to the accompanying drawings, and the embodiments are implemented on the premise of the technical solution of the present invention, and detailed embodiments and specific working procedures are given, but the scope of the present invention is not limited to the following embodiments.
As shown in fig. 1 and 2, the substrate missing adding detection device for the full-automatic optical immunoassay analyzer of the utility model comprises a fixing frame 1, wherein the fixing frame 1 is used for vertically fixing the device at a proper position; a shading box 2 is arranged on the fixed frame 1, a light-transmitting liquid path pipe 3 is vertically arranged in the shading box 2, the upper pipe orifice and the lower pipe orifice of the light-transmitting liquid path pipe 3 are respectively communicated with an upper shading liquid path pipe 5.1 and a lower shading liquid path pipe 5.2 through pipe joints 4.1 and 4.2, and the upper shading liquid path pipe 5.1 and the lower shading liquid path pipe 5.2 respectively vertically extend out of the top wall and the bottom wall of the shading box 2; the light-transmitting liquid path pipe 3 is sleeved with a photoelectric bubble sensor 6 for detecting bubbles in the light-transmitting liquid path pipe, and a signal line and a power line of the photoelectric bubble sensor 6 are hermetically connected with a control and data processing unit 7 after passing through the shading box 2. The control and data processing unit 7 is used for providing working voltage for the photoelectric bubble sensor 6, receiving detection signals of the photoelectric bubble sensor 6, analyzing and processing the detection signals and judging whether substrates are added in a missing mode during sample detection.
The shading box 2 is used for shading natural light so as to prevent external light from influencing the substrate in the light transmitting liquid pipe 3, change the characteristics of the substrate and influence the detection result of the sample.
Advantageously or exemplarily, as shown in fig. 2, the control and data processing unit comprises:
a single chip Microcomputer (MCU) which adopts an STM32 platform as a control and data processing core of the whole substrate missing adding detection device; and the photoelectric bubble sensor working voltage control circuit is used for receiving the control signal sent by the singlechip and realizing the connection and the disconnection of the working voltage of the photoelectric bubble sensor.
Because the substrate can not receive illumination for a long time, and the substrate characteristics can not be changed by short-term illumination for tens of seconds, in order to avoid the infrared light of the photoelectric bubble sensor 6 from generating illumination influence on the substrate when the substrate is not needed to be filled, the working voltage of the photoelectric bubble sensor 6 is controlled to be switched on and off by the working voltage control circuit of the photoelectric bubble sensor, and the working voltage of the photoelectric bubble sensor 6 is switched on when the substrate is needed to be filled; otherwise, the system is closed.
The detection signal processing circuit is used for converting a detection signal output by the photoelectric bubble sensor into an input signal suitable for the singlechip; the CAN communication module is used for uploading a substrate missing detection result sent by the singlechip to the analyzer industrial personal computer, and the analyzer industrial personal computer displays the substrate pipeline missing information on a client software interface to remind an instrument operator of timely carrying out fault treatment.
The power module adopts 24V power supply, converts 5V and 3.3V through a voltage stabilizing voltage chip, wherein 5V provides working voltage for the electric bubble sensor 6 and the detection signal processing circuit, and 3.3V provides working voltage for the singlechip and the CAN communication module.
Further, as shown in fig. 2, the working voltage control circuit of the photoelectric bubble sensor includes a triode Q1, a base of the triode Q1 is connected with a control signal output end of the single chip microcomputer through a current limiting resistor R4, a collector of the triode Q1 is connected with a power negative electrode interface of the photoelectric bubble sensor, a power positive electrode interface of the photoelectric bubble sensor is connected with a 5V power output end of the power module, an emitter of the triode Q1 is grounded, and a high potential end of the current limiting resistor R4 is grounded through a pull-down resistor R5; the singlechip sends out a control signal to control the conduction and the cut-off of the triode Q1, so as to realize the connection and the cut-off of the working voltage of the photoelectric bubble sensor 6; the circuit is simple to manufacture and reliable in work.
The detection signal processing circuit comprises a series circuit consisting of resistors R1 and R2, an integrated operational amplifier U1 and a filter capacitor C1; u1 homophase input end warp is put to integrated fortune resistance R1 is connected with photoelectric bubble sensor detection signal output, and U1 inverting input end is put with integrated fortune to integrated fortune is put U1 output and is connected, and integrated fortune is put U1 output and is passed through resistance R3 and be connected with singlechip signal input part, and the warp filter capacitor C1 ground connection.
The working voltage of the photoelectric bubble sensor 6 is 5V, the output signal is TTL level, and the signal level received by the single chip microcomputer is 3.3V, so that the output signal of the photoelectric bubble sensor 6 is adjusted to be within 3.3V through the voltage division of the resistors R1 and R2; the following circuit formed by the integrated operational amplifier U1 increases the stability of the detection signal of the photoelectric bubble sensor 6, and the detection signal is sent to the singlechip for analysis and processing through the current-limiting filter circuit formed by the resistor R3 and the capacitor C1.
Claims (2)
1. A substrate leaks adds detection device for full-automatic optical immunoassay appearance which characterized in that: the device comprises a fixed frame and a light shielding box arranged on the fixed frame, wherein a light transmitting liquid path pipe is vertically arranged in the light shielding box, the upper pipe opening and the lower pipe opening of the light transmitting liquid path pipe are respectively communicated with the upper light shielding liquid path pipe and the lower light shielding liquid path pipe through pipe joints, and the upper light shielding liquid path pipe and the lower light shielding liquid path pipe respectively vertically extend out of the light shielding box; the light-transmitting liquid path pipe is provided with a photoelectric bubble sensor for detecting bubbles in the light-transmitting liquid path pipe, and a signal line and a power line of the photoelectric bubble sensor hermetically penetrate through the outside of the light-shielding box and are connected with the control and data processing unit;
and the control and data processing unit is used for providing working voltage for the photoelectric bubble sensor, receiving a detection signal of the photoelectric bubble sensor, analyzing and processing the detection signal and judging whether the substrate is added in a missing manner or not during sample detection.
2. The substrate missing detection device for the fully automatic optical immunoassay analyzer according to claim 1, characterized in that: the control and data processing unit comprises
The single chip microcomputer is used for controlling substrate missing adding detection and processing data;
the photoelectric bubble sensor working voltage control circuit is used for receiving a control signal sent by the singlechip and realizing the connection and the disconnection of the working voltage of the photoelectric bubble sensor;
the working voltage control circuit of the photoelectric bubble sensor comprises a triode Q1, wherein the base electrode of the triode Q1 is connected with the control signal output end of the single chip microcomputer through a current-limiting resistor R4, the collector electrode of the triode Q1 is connected with the negative electrode interface of the power supply of the photoelectric bubble sensor, the positive electrode interface of the power supply of the photoelectric bubble sensor is connected with the 5V power supply output end of the power supply module, the emitting electrode of the triode Q1 is grounded, and the high-potential end of the current-limiting resistor R4 is grounded through a pull-down resistor R5;
the detection signal processing circuit is used for converting the detection signal output by the photoelectric bubble sensor into an input signal suitable for the singlechip;
the detection signal processing circuit comprises a series circuit consisting of resistors R1 and R2, an integrated operational amplifier U1 and a filter capacitor C1; the non-inverting input end of the integrated operational amplifier U1 is connected with the detection signal output end of the photoelectric bubble sensor through the resistor R1, the inverting input end of the integrated operational amplifier U1 is connected with the output end of the integrated operational amplifier U1, and the output end of the integrated operational amplifier U1 is connected with the signal input end of the single chip microcomputer through a resistor R3 and is grounded through the filter capacitor C1;
the CAN communication module is used for uploading a substrate missing adding detection result sent by the singlechip to an upper computer of the analyzer;
and the power supply module is used for providing working voltage for the photoelectric bubble sensor, the detection signal processing circuit, the singlechip and the CAN communication module.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222878458.XU CN218674703U (en) | 2022-10-31 | 2022-10-31 | Substrate missing adding detection device for full-automatic optical immunoassay analyzer |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222878458.XU CN218674703U (en) | 2022-10-31 | 2022-10-31 | Substrate missing adding detection device for full-automatic optical immunoassay analyzer |
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| Publication Number | Publication Date |
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| CN218674703U true CN218674703U (en) | 2023-03-21 |
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| CN202222878458.XU Active CN218674703U (en) | 2022-10-31 | 2022-10-31 | Substrate missing adding detection device for full-automatic optical immunoassay analyzer |
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- 2022-10-31 CN CN202222878458.XU patent/CN218674703U/en active Active
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