CN218673853U - Reagent surplus monitoring devices and sample analysis appearance - Google Patents
Reagent surplus monitoring devices and sample analysis appearance Download PDFInfo
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- CN218673853U CN218673853U CN202222694877.8U CN202222694877U CN218673853U CN 218673853 U CN218673853 U CN 218673853U CN 202222694877 U CN202222694877 U CN 202222694877U CN 218673853 U CN218673853 U CN 218673853U
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Abstract
The application discloses reagent surplus monitoring devices and sample analysis appearance, this reagent surplus monitoring devices includes: a reagent container for containing a reagent; the pressure sensing module is used for generating corresponding electric signals based on the change of the pressure applied to the pressure sensing module by the reagent container so as to determine the pressure applied to the pressure sensing module by the reagent container; the pressure sensing module comprises a single-point weighing sensor, and the reagent allowance monitoring device also comprises a base; one end of the single-point weighing sensor is used for bearing the reagent container, and the other end of the single-point weighing sensor is fixedly connected with the base. Based on the mode, the allowance of the reagent contained in the reagent container can be detected through the pressure sensing module, so that the accuracy of allowance monitoring is improved.
Description
Technical Field
The application relates to the technical field of reagent detection, in particular to a reagent allowance monitoring device and a sample analyzer.
Background
In the prior art, when sample detection is performed, a corresponding reagent needs to be extracted from a reagent container for relevant processing, so whether the residual quantity of the corresponding reagent in the reagent container is sufficient or not and whether the corresponding reagent needs to be supplemented or not becomes an important task in the sample detection.
The prior art has the defect that the float switch is usually adopted to monitor the residual quantity of the reagent in the reagent container, and due to the characteristics of the float switch, the float switch can only judge whether the reagent still exists in the reagent, but cannot accurately estimate the residual quantity of the reagent, so that the accuracy of the existing residual quantity detection is poor.
SUMMERY OF THE UTILITY MODEL
The main technical problem who solves of this application is how to improve the accurate nature of surplus monitoring.
In order to solve the above technical problem, the first technical solution adopted by the present application is: a reagent balance monitoring device comprising: a reagent container for containing a reagent; the pressure sensing module is used for generating corresponding electric signals based on the change of the pressure received by the pressure sensing module so as to determine the pressure applied by the reagent container to the pressure sensing module; the pressure sensing module comprises a single-point weighing sensor, and the reagent allowance monitoring device also comprises a base; one end of the single-point weighing sensor is used for bearing the reagent container, and the other end of the single-point weighing sensor is fixedly connected with the base.
The single-point type weighing sensor is provided with a hollow area, and the single-point type weighing sensor is used for generating corresponding electric signals based on shape change of the hollow area.
The pressure sensing module further comprises a bearing part and an intermediate part, the intermediate part is detachably connected with the bearing part and the single-point weighing sensor respectively, and the bearing part is used for bearing a reagent container.
The device also comprises a processing module; the processing module is electrically connected with the pressure sensing module and is used for determining the pressure applied to the pressure sensing module by the reagent container based on the electric signal.
The reagent residue monitoring device also comprises a signal amplification module and an analog-to-digital conversion module; the pressure sensing module is electrically connected with the signal amplification module, the signal amplification module is electrically connected with the analog-to-digital conversion module, and the analog-to-digital conversion module is electrically connected with the processing module.
The signal amplification module comprises a signal amplification circuit, a de-biasing circuit and an amplification shaping circuit; the output end of the pressure sensing module is electrically connected with the input end of the signal amplification circuit, the output end of the signal amplification circuit is electrically connected with the input end of the de-biasing circuit, the output end of the de-biasing circuit is electrically connected with the input end of the amplification shaping circuit, and the output end of the amplification shaping circuit is electrically connected with the input end of the analog-to-digital conversion module.
The reagent allowance monitoring device further comprises a power supply module, the signal amplification module further comprises an ultra-low noise voltage stabilizing circuit, the power supply module is electrically connected with the ultra-low noise voltage stabilizing circuit, and the ultra-low noise voltage stabilizing circuit is electrically connected with the pressure sensing module, the signal amplification circuit, the de-biasing circuit and the amplification shaping circuit respectively.
The reagent allowance monitoring device further comprises a power supply module, the analog-to-digital conversion module comprises a direct current voltage transformation circuit and an analog-to-digital conversion circuit, the power supply module is electrically connected with the direct current voltage transformation circuit, and the direct current voltage transformation circuit is electrically connected with the analog-to-digital conversion circuit.
The processing module is specifically configured to determine the number of times that the reagent in the reagent container can be supplied to detect the sample based on the pressure detected by the pressure sensing module when the unit-time variation amplitude of the pressure detected by the pressure sensing module is smaller than a preset variation amplitude.
In order to solve the above technical problem, the second technical solution adopted by the present application is: a sample analyzer comprises the reagent residual amount monitoring device.
The beneficial effect of this application lies in: be different from prior art, in the technical scheme of this application, through set up the pressure sensing module in reagent surplus detection device to on arranging the pressure sensing module in the reagent container, monitor through applying the pressure on the pressure sensing module to the reagent container, confirm the change situation of reagent surplus in the reagent container, with the realization to the accurate monitoring of reagent surplus, improved the precision of surplus monitoring.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.
FIG. 1 is a schematic view of the structure of one embodiment of the reagent level monitoring device of the present application;
FIG. 2 is a schematic view of a portion of an embodiment of a reagent level monitoring apparatus according to the present application;
FIG. 3 is a second schematic diagram of a partial structure of an embodiment of the device for monitoring the remaining amount of reagent according to the present application;
FIG. 4 is a third schematic view of a partial structure of an embodiment of the reagent level monitoring apparatus according to the present application;
FIG. 5 is a schematic block diagram of an embodiment of a sample analyzer according to the present application.
The reference signs are: the reagent container 11, the pressure sensing module 12, the single-point load cell 121, the bearing member 122, the intermediate member 123, the base 13, the sample analyzer 20, and the reagent balance monitoring device 21.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. It is to be understood that the specific embodiments described herein are merely illustrative of the application and are not limiting of the application. It should be further noted that, for the convenience of description, only some of the structures related to the present application are shown in the drawings, not all of the structures. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
The terms "first", "second" and "third" in this application are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implying any indication of the number of technical features indicated. Thus, a feature defined as "first," "second," or "third" may explicitly or implicitly include at least one of the feature. In the description of the present application, "plurality" means at least two, e.g., two, three, etc., unless explicitly specifically limited otherwise. In the embodiment of the present application, all directional indicators (such as up, down, left, right, front, rear \8230;) are used only to explain the relative positional relationship between the components, the motion situation, etc. at a specific posture (as shown in the drawing), and if the specific posture is changed, the directional indicator is changed accordingly. Furthermore, the terms "include" and "have," as well as any variations thereof, are intended to cover non-exclusive inclusions. For example, a process, method, system, article, or apparatus that comprises a list of steps or elements is not limited to only those steps or elements listed, but may alternatively include other steps or elements not listed, or inherent to such process, method, article, or apparatus.
Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein can be combined with other embodiments.
First, a reagent remaining amount monitoring device is provided, referring to fig. 1, fig. 1 is a schematic structural diagram of an embodiment of the reagent remaining amount monitoring device, and as shown in fig. 1, the reagent remaining amount monitoring device includes a reagent container 11 and a pressure sensing module 12.
The reagent container 11 may be provided therein with a holding chamber, and the holding chamber may be connected to or separated from the outside through an openable/closable opening provided in the reagent container 11, and the reagent may be replenished into the holding chamber through the opening provided in the reagent container 11, or may be extracted through the opening provided in the reagent container 11, which is not limited herein.
The pressure sensing module 12 may be disposed at the bottom of the reagent container 11, that is, the reagent container 11 may be disposed on the pressure sensing module 12 to bear the reagent container 11 based on the pressure sensing module 12, so as to implement monitoring of the weight change of the reagent container 11 by the pressure sensing module 12, specifically, the pressure sensing module 12 may generate a corresponding electrical signal based on the change of the pressure applied thereto to indicate the magnitude of the pressure, and then determine the pressure applied to the pressure sensing module 12 by the reagent container 11 through the change of the electrical signal, thereby completing monitoring of the weight change of the reagent container 11.
It should be noted that, in practice, the pressure applied to the pressure sensing module 12 when any actual reagent container 11 is not loaded on the pressure sensing module 12 can be predetermined and recorded as initial pressure, then reagent is injected into the reagent container 11 for storage, and the pressure applied to the pressure sensing module 12 by the reagent container 11 with the reagent stored later is monitored and recorded as real-time pressure. The weight corresponding to the reagent can be determined by subtracting the initial pressure from the real-time pressure to obtain a corresponding differential pressure, and the determination of the remaining amount of the reagent in the reagent container 11 can be completed based on the weight corresponding to the reagent.
Specifically, the reagent in the reagent container 11 may be any type of reagent, such as a cleaning solution, and is not limited herein. The pressure sensing module 12 may be any type of pressure sensor and is not limited thereto.
Be different from prior art, in the technical scheme of this application, through set up pressure sensing module in reagent surplus detection device to on placing the pressure sensing module in the reagent container, monitor through the pressure of exerting on pressure sensing module to the reagent container, confirm the change situation of reagent surplus in the reagent container, with the realization to the accurate monitoring of reagent surplus, improved the accuracy nature of surplus monitoring.
In one embodiment, as shown in fig. 2 to 4, the pressure sensing module 12 includes a single-point load cell 121, and the reagent level monitoring apparatus further includes a base 13.
One end of the single-point load cell 121 is used to carry the reagent container 11 to detect a change in pressure applied by the reagent container 11 to the pressure sensing module 12, and the other end of the single-point load cell 121 is fixedly connected to the base 13 to support the pressure sensing module 12 and the reagent container 11 based on the base 13.
The single-point weighing sensor 121 can be provided with a corresponding hollowed-out area, when one end of the single-point weighing sensor 121 bears a certain pressure, one end of the single-point weighing sensor 121 is provided with a structure surrounding the hollowed-out area to deform to a certain extent, the deformation degree corresponding to the deformation is in positive correlation with the pressure, namely, the larger the borne pressure is, the larger the deformation is, the single-point weighing sensor 121 can be specifically used for generating a corresponding electric signal based on the deformation size of the hollowed-out area, so as to output information of the pressure borne by one end of the single-point weighing sensor 121 through the electric signal, and further can complete the detection of the residual quantity of the reagent in the reagent container 11 based on the information, the information of the residual quantity of the reagent obtained based on the mode is more accurate, and the accuracy of the monitoring of the residual quantity of the reagent is improved.
In particular, the base 13 may be a part of a housing, and a receiving cavity may be disposed in the housing, and both the reagent container 11 and the pressure sensing module 12 may be disposed in the receiving cavity of the housing, and may be disposed on the base 13 at the bottom of the housing.
Optionally, as shown in fig. 2 to 4, the pressure sensing module 12 further comprises a carrier 122 and an intermediate piece 123, the intermediate piece 123 being detachably connected to the carrier 122 and the single-point load cell 121, respectively, the carrier being adapted to carry reagent containers.
Specifically, a first through hole and a first screw may be disposed on the intermediate member 123, a first screw hole may be disposed on the single-point load cell 121, a nut of the first screw may abut against a side of the intermediate member 123 away from the single-point load cell 121, and a screw of the first screw passes through the first through hole and is in threaded connection with the first screw hole, so that the intermediate member 123 and the single-point load cell 121 are detachably connected.
The intermediate member 123 may further include a second through hole and a second screw, the carrier 122 may include a second screw hole, a nut of the second screw may abut against a side of the intermediate member 123 far from the carrier 122, and a screw of the second screw passes through the second through hole and is in threaded connection with the second screw hole, so that the intermediate member 123 and the carrier 122 are detachably connected.
It should be noted that the above is only an example of one detachable connection manner, and the detachable connection manner may also be other manners, and may be determined according to actual needs, and is not limited herein.
In an embodiment, the reagent balance monitoring device further comprises a processing module.
The processing module is electrically connected to the pressure sensing module 12, and the processing module is configured to determine the pressure applied by the reagent container 11 to the pressure sensing module 12 based on the electrical signal.
Specifically, the reagent remaining amount monitoring device may further include a display module electrically connected to the processing module. It should be noted that the display module and the processing module may be an upper computer or a part of the upper computer, and may be configured to receive the electrical signal to analyze and determine the pressure applied by the reagent container 11 to the pressure sensing module 12, so as to determine the remaining amount of the reagent.
Optionally, the reagent remaining amount monitoring device further comprises a signal amplification module and an analog-to-digital conversion module.
The pressure sensing module 12 is electrically connected with the signal amplifying module, the signal amplifying module is electrically connected with the analog-to-digital conversion module, and the analog-to-digital conversion module is electrically connected with the processing module.
After the pressure applied by the reagent container 11 is converted into an electric signal of an analog signal through the pressure sensing module 12, the electric signal with lower intensity can be amplified through the signal amplification module, and then the electric signal is converted into a digital signal through the analog-to-digital conversion module, so that the information related to the pressure contained in the electric signal is clarified.
Further, the signal amplification module comprises a signal amplification circuit, a de-biasing circuit and an amplification shaping circuit.
The output end of the pressure sensing module 12 is electrically connected to the input end of the signal amplifying circuit, the output end of the signal amplifying circuit is electrically connected to the input end of the de-biasing circuit, the output end of the de-biasing circuit is electrically connected to the input end of the amplifying and shaping circuit, and the output end of the amplifying and shaping circuit is electrically connected to the input end of the analog-to-digital conversion module.
Specifically, the composition of the amplified signal module in the above example is only an example, and the amplified signal module may also be another type of module with signal amplification capability, which may be determined according to actual needs, and is not limited herein.
Furthermore, the reagent residue monitoring device further comprises a power module, the signal amplification module further comprises an ultra-low noise voltage stabilizing circuit, the power module is electrically connected with the ultra-low noise voltage stabilizing circuit, and the ultra-low noise voltage stabilizing circuit is electrically connected with the pressure sensing module 12, the signal amplification circuit, the de-biasing circuit and the amplification shaping circuit respectively.
Specifically, the power supply voltage provided by the power supply module can be subjected to voltage stabilization through the ultra-low noise voltage stabilizing circuit, and then the power supply voltage subjected to voltage stabilization is respectively provided to the pressure sensing module 12, the signal amplifying circuit, the de-biasing circuit and the amplifying and shaping circuit, so that the stability of signal amplification can be ensured, and the accuracy of margin monitoring can be further improved.
Furthermore, the reagent allowance monitoring device also comprises a power supply module, the analog-to-digital conversion module comprises a direct current voltage transformation circuit and an analog-to-digital conversion circuit, the power supply module is electrically connected with the direct current voltage transformation circuit, and the direct current voltage transformation circuit is electrically connected with the analog-to-digital conversion circuit.
Furthermore, the analog-to-digital conversion module further comprises an ultra-low noise reference source circuit, and the ultra-low noise reference source circuit is electrically connected with the analog-to-digital conversion module.
Specifically, the composition of the analog-to-digital conversion module in the above example is only an example, and the analog-to-digital conversion module may also be another type of module with an analog-to-digital conversion capability, which may be determined according to actual needs, and is not limited herein.
Optionally, the processing module is specifically configured to determine the number of times of detection of the feedable sample of the reagent in the reagent container 11 based on the pressure detected by the pressure sensing module 12 when the time-unit variation amplitude of the pressure detected by the pressure sensing module 12 is smaller than the preset variation amplitude.
Specifically, when it is detected that the variation range per unit time of the pressure monitored by the pressure sensing module 12 is smaller than the preset variation range, it may be determined that the reagent container 11 in the reagent remaining amount monitoring device is in the idle state, at this time, the total weight G1 of the reagent container 11 and the reagent therein may be determined based on the pressure detected by the pressure sensing module 12, and then the number of times of detection of the sample that may be supplied to the reagent in the reagent container 11 may be determined based on the following formula:
N＝(G1-G3)/G2；
in the above formula, N is the number of sample tests that can be performed on the reagent in the reagent container 11, i.e. the number of sample tests that can be supported by the remaining reagent in the reagent container 11, G1 is the total weight G1 of the current reagent container 11 and the reagent therein, G3 is the weight of the reagent container 11 itself, and G2 is the weight of the reagent required for a single sample test.
Based on the above manner, when the reagent container 11 is in the idle state, the latest state of the reagent remaining in the reagent container 11 can be updated in time for the user to check and perform corresponding operations based on the latest state, so that the reliability of the reagent remaining monitoring device is improved.
The present application further provides a sample analyzer, referring to fig. 5, fig. 5 is a schematic structural diagram of an embodiment of the sample analyzer of the present application, and as shown in fig. 5, the sample analyzer 20 includes a reagent remaining amount monitoring device 21, and the reagent remaining amount monitoring device 21 may be any one of the reagent remaining amount monitoring devices described in the foregoing embodiments, and details are not repeated here.
Specifically, the sample analyzer 20 may extract a corresponding reagent from the reagent container 11 of the reagent balance monitoring device, so as to perform a detection reaction on the corresponding sample, so as to complete sample analysis according to the relevant parameters of the detection reaction.
Be different from prior art, in the technical scheme of this application, through set up pressure sensing module in reagent surplus detection device to on placing the pressure sensing module in the reagent container, monitor through the pressure of exerting on pressure sensing module to the reagent container, confirm the change situation of reagent surplus in the reagent container, with the realization to the accurate monitoring of reagent surplus, improved the accuracy nature of surplus monitoring.
The above description is only for the purpose of illustrating embodiments of the present application and is not intended to limit the scope of the present application, and all modifications of equivalent structures and equivalent processes, which are made by the contents of the specification and the drawings of the present application or are directly or indirectly applied to other related technical fields, are also included in the scope of the present application.
Claims (10)
1. A reagent remaining amount monitoring device, comprising:
a reagent container for containing a reagent;
the pressure sensing module is used for generating corresponding electric signals based on the change of the pressure applied to the pressure sensing module by the reagent container so as to determine the pressure applied to the pressure sensing module by the reagent container;
the pressure sensing module comprises a single-point weighing sensor, and the reagent allowance monitoring device further comprises a base;
one end of the single-point weighing sensor is used for bearing the reagent container, and the other end of the single-point weighing sensor is fixedly connected with the base.
2. The device of claim 1, wherein a hollowed-out area is disposed on the single-point load cell, and the single-point load cell is configured to generate the corresponding electrical signal based on a change in shape of the hollowed-out area.
3. The apparatus of claim 2, wherein the pressure sensing module further comprises a carrier and an intermediate piece, the intermediate piece being detachably connected to the carrier and the single-point load cell, respectively, the carrier being configured to carry the reagent container.
4. The apparatus of any one of claims 1 to 3, further comprising a processing module;
the processing module is electrically connected with the pressure sensing module and is used for determining the pressure applied by the reagent container to the pressure sensing module based on the electric signal.
5. The device of claim 4, wherein the reagent residue monitoring device further comprises a signal amplification module and an analog-to-digital conversion module;
the pressure sensing module is electrically connected with the signal amplification module, the signal amplification module is electrically connected with the analog-to-digital conversion module, and the analog-to-digital conversion module is electrically connected with the processing module.
6. The apparatus of claim 5, wherein the signal amplification module comprises a signal amplification circuit, a de-biasing circuit, and an amplification shaping circuit;
the output end of the pressure sensing module is electrically connected with the input end of the signal amplifying circuit, the output end of the signal amplifying circuit is electrically connected with the input end of the de-biasing circuit, the output end of the de-biasing circuit is electrically connected with the input end of the amplifying and shaping circuit, and the output end of the amplifying and shaping circuit is electrically connected with the input end of the analog-to-digital conversion module.
7. The apparatus of claim 6, wherein the reagent remaining amount monitoring apparatus further comprises a power module, the signal amplification module further comprises an ultra-low noise voltage stabilizing circuit, the power module is electrically connected to the ultra-low noise voltage stabilizing circuit, and the ultra-low noise voltage stabilizing circuit is electrically connected to the pressure sensing module, the signal amplification circuit, the de-biasing circuit and the amplification and shaping circuit respectively.
8. The apparatus of claim 5, wherein the reagent remaining amount monitoring device further comprises a power module, the analog-to-digital conversion module comprises a DC transformer circuit and an analog-to-digital conversion circuit, the power module is electrically connected to the DC transformer circuit, and the DC transformer circuit is electrically connected to the analog-to-digital conversion circuit.
9. The device according to claim 4, wherein the processing module is specifically configured to determine the number of detections of the feedable sample of the reagent in the reagent container based on the pressure detected by the pressure sensing module when the time-unit variation amplitude of the pressure monitored by the pressure sensing module is smaller than a preset variation amplitude.
10. A sample analyzer comprising a reagent-remaining-amount monitoring device according to any one of claims 1 to 9.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222694877.8U CN218673853U (en) | 2022-10-12 | 2022-10-12 | Reagent surplus monitoring devices and sample analysis appearance |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222694877.8U CN218673853U (en) | 2022-10-12 | 2022-10-12 | Reagent surplus monitoring devices and sample analysis appearance |
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| Publication Number | Publication Date |
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| CN218673853U true CN218673853U (en) | 2023-03-21 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202222694877.8U Active CN218673853U (en) | 2022-10-12 | 2022-10-12 | Reagent surplus monitoring devices and sample analysis appearance |
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