CN218646986U - A serum endotoxin detection device - Google Patents

Abstract

The utility model belongs to the technical field of bacterial endotoxin detection, a serum endotoxin detection device is disclosed, which comprises a base, the base is connected with a detection box, the detection box is connected with a cover body, the cover body is provided with a buckle and a LED lamp, the detection box is provided with a detection plate, a recovery tank, a water bath box and a heating device, the detection plate is provided with a handle and is provided with a test tube hole, an arc-shaped clamp is arranged in the test tube hole, the arc-shaped clamp is connected with a connecting rod, the detection plate is provided with a spring hole, the spring hole is connected with a spring, the detection plate is connected with a lifting plate, the bottom of the lifting plate is connected with a hydraulic rod, the base is provided with a control panel, and the control panel is provided with a digital display thermometer, a temperature adjusting knob, a power switch, a light switch, a pause switch, an ascending switch and a descending switch; the utility model provides a problem that detection efficiency is low among the prior art, be applicable to the detection of serum endotoxin in the medical treatment process.

Description

A serum endotoxin detection device

technical field

The utility model relates to the technical field of bacterial endotoxin detection, in particular to a serum endotoxin detection device.

Background technique

With the development of medical and health services, serum endotoxin detection has become one of the routine tasks of medical and health care. Endotoxin is a complex of lipopolysaccharide and protein on the cell wall of Gram-negative bacteria. When the bacteria die or autolyze endotoxin is released. A large amount of endotoxin entering the blood will cause a fever reaction, that is, a "pyrogenic reaction". Endotoxin is closely related to a variety of infectious diseases. The deterioration of the disease is often accompanied by the increase of the endotoxin content, and the remission of the disease is often accompanied by the decrease of the endotoxin content. Therefore, rapid detection of endotoxin content can provide a reference for the diagnosis and prognosis of clinically relevant diseases. There are many methods for detecting serum endotoxin, and the most commonly used method is the limulus test. Limulus test is also the best method for endotoxin detection in the world so far. It is simple, fast, sensitive and accurate. Therefore, it has been designated as the legal endotoxin test method by European and American Pharmacopoeia and Chinese Pharmacopoeia, and has been adopted by countries all over the world. Limulus reagent assay methods include gel method, dynamic turbidity method, terminal turbidity method, dynamic chromogenic method and terminal chromogenic method, the most common being gel method. The existing gel method for serum endotoxin detection does not have a special and systematic detection device, and the operation process is relatively complicated. During the detection process, it is necessary to hold the test tube and turn it upside down to observe the gel formation. Only one experimental sample can be observed at a time. The observation efficiency is low, and there is no comparison with the comparative experimental sample, which is not conducive to a clear judgment of the experimental results. In view of the above problems, a serum endotoxin detection device is proposed.

Utility model content

The utility model intends to provide a serum endotoxin detection device to solve the problem of inefficiency caused by the need to hold the test tube upside down to observe the gel formation in the prior art and only observe one experimental sample at a time.

In order to achieve the above object, the utility model provides the following technical solutions:

The basic technical solution provided by the utility model is: a serum endotoxin detection device, including a base, the upper part of the base is connected with a detection box, the top of the detection box is rotatably connected with a cover, and the inside of the detection box is provided with a water bath box, the bottom of the water bath box is provided with a heating device, the inside of the detection box is provided with a detection plate, the detection plate has a test tube hole, the two sides of the detection plate are rotated and connected with a lifting plate, and the bottom of the lifting plate is connected with a A hydraulic rod, the free end of the hydraulic rod is connected to the detection box, the base is provided with a socket, the socket is connected to a power supply, the front of the base is provided with a control panel, and the control panel is provided with a digital display thermometer, The control panel is provided with a temperature adjustment knob, the temperature adjustment knob is electrically connected with the heating device, the control panel is provided with a power switch, and the control panel is also provided with a hydraulic lever control switch, and the hydraulic lever The control switch includes a pause switch, an up switch and a down switch, and the pause switch, the up switch and the down switch are all electrically connected to the hydraulic rod.

The principle of the basic technical solution: when the serum endotoxin testing personnel are testing, plug in the plug, turn on the power switch, and provide electric energy for the whole device. The temperature adjustment knob controls the heating device and then controls the temperature of the water in the water bath box. The temperature of the water in the water bath is controlled within an appropriate range, and the prepared LAL reagent, the sample to be tested and the comparison sample are added to the test tube in a certain proportion according to the experimental requirements, and then the test tubes are put into the test tube holes respectively, and the lid is closed , the water bath is heated to the time required by the experiment, the hydraulic rod can lift the detection board to a certain height, the hydraulic rod control switch can control the rise, fall and pause of the hydraulic rod, adjust the hydraulic rod control switch, after the detection board rises to a certain height, Then rotate the detection plate to a certain angle, observe the gel shedding, and make a record of the experiment, restore the device to its original state, and take out the test tube.

The beneficial effect of the basic technical solution is: the above technical solution can carry out systematic detection, and can detect multiple samples at one time, and can also perform comparison when each test tube is inverted, which not only increases the detection efficiency, but also makes the comparison clearer The result of the judgment experiment.

Preferably, the test tube hole is provided with a test tube clamping device, the test tube clamping device includes an arc clamp, the arc clamp is located inside the test tube hole, the arc clamp is connected with a connecting rod, and the detection plate A spring hole is opened, and a spring is connected to the spring hole, and the connecting rod is passed through the spring hole to connect with the free end of the spring

Through the above arrangement, the test tube can be more stable in the test tube hole and not easy to fall off.

Preferably, an LED lamp is provided inside the cover, a light switch is provided on the control panel, and the light switch is electrically connected to the LED lamp.

Through the above settings, the field of view is clearer when observing the gel formation.

Preferably, the detection plate is provided with a handle, and a recovery tank is provided inside the detection box, and the recovery tank is used to recover samples that have not formed gel in the test tube.

With the above settings, the recovery tank can collect samples that do not form gels.

Preferably, the cover is provided with buckles.

Through the above arrangement, the cover body is tightly buckled on the detection box to reduce the loss of temperature in the water bath box.

Description of drawings

Fig. 1 is a schematic structural view of a serum endotoxin detection device of the present invention;

Fig. 2 is the front view of Fig. 1;

Fig. 3 is a structural schematic diagram of a control panel of a serum endotoxin detection device of the present invention;

Fig. 4 is a partial structural schematic diagram of a serum endotoxin detection device of the present invention;

Fig. 5 is a structural schematic diagram of a test tube clamping device of a serum endotoxin detection device of the present invention;

The names of the corresponding symbols in the drawings are:

Base 1, lifting plate 2, control panel 3, digital display thermometer 301, pause switch 302, up switch 303, down switch 304, temperature adjustment knob 305, light switch 306, power switch 307, detection box 4, heating device 5, cover Body 6, buckle 7, LED light 8, detection plate 9, handle 10, test tube hole 11, water bath box 12, recovery tank 13, spring hole 14, hydraulic rod 15, arc clip 16, connecting rod 17, spring 18.

Detailed ways

Below in conjunction with accompanying drawing and embodiment the utility model is described in further detail:

As shown in Figures 1-5, a serum endotoxin detection device is characterized in that it includes a base 1, a detection box 4 is connected to the top of the base 1, and a cover 6 is connected to the top of the detection box 4 in rotation, and the cover 6 is provided There is a buckle 7, an LED light 8 is provided inside the cover body 6, a water bath box 12 is provided inside the detection box 4, a heating device 5 is provided at the bottom of the water bath box 12, and a recovery tank 13 is provided inside the detection box 4, and the recovery tank 13 is used for Recover the sample that has not formed gel in the test tube. The test box 4 is equipped with a test plate 9 inside. The test plate 9 is provided with a handle 10. The test plate 9 has a test tube hole 11. The test tube hole 11 is provided with a test tube clamping device. The device includes an arc clip 16, which is located inside the test tube hole 11, the arc clip 16 is connected with a connecting rod 17, the detection plate 9 is opened with a spring hole 14, the spring hole 14 is connected with a spring 18, and the connecting rod 17 is penetrated The spring hole 14 is connected with the free end of the spring 18. The two sides of the detection plate 9 are rotated and connected with the lifting plate 2. The bottom of the lifting plate 2 is connected with the hydraulic rod 15. The free end of the hydraulic rod 15 is connected with the detection box 4. The base 1 A socket is provided, the socket is connected to a power supply, a control panel 3 is provided on the front of the base 1, a digital display thermometer 301 is provided on the control panel 3, a temperature adjustment knob 305 is provided on the control panel 3, and the temperature adjustment knob 305 is electrically connected to the heating device 5, Control panel 3 is provided with power switch 307, and control panel 3 is also provided with hydraulic lever control switch, and hydraulic lever control switch comprises pause switch 302, ascending switch 303 and descending switch 304, pause switch 302, ascending switch 303 and descending switch 304 and hydraulic pressure The rods 15 are electrically connected, and the control panel 3 is also provided with a light switch 306 , and the light switch 306 is electrically connected to the LED lamp 8 .

The specific implementation process is as follows: when the serum endotoxin testing personnel are testing, they plug in the plug, turn on the power switch 307, adjust the temperature adjustment knob 305 to control the temperature of the water in the water bath box 12 in a suitable range, and put the prepared LAL reagent into a suitable range. The test sample and comparison sample are added to the test tube in a certain proportion according to the experimental requirements, and then the test tubes are put into the test tube holes 11 respectively. Fall off from the test tube hole 11, cover the cover body 6, heat the water bath to the time required for the experiment, adjust the hydraulic lever control switch, and wait for the detection plate 9 to rise to a certain height, hold the handle 10 to rotate the detection plate 9 to a certain angle, and turn on the light Switch 306, with the help of LED light 8, observe the gel shedding situation, the sample that has not formed gel falls off to the recovery tank 13 for recycling, make experimental records, restore the device to its original state, and finally take out the test tube.

What is described above is only the embodiment of the utility model, and common knowledge such as specific technical solutions or characteristics known in the solutions are not described too much here. It should be pointed out that for those skilled in the art, without departing from the technical solution of the utility model, some modifications and improvements can also be made, and these should also be regarded as the protection scope of the utility model, and these will not affect the utility model. Effects of utility model implementation and practicability of patents. The scope of protection required by this application shall be based on the content of the claims, and the specific implementation methods and other records in the specification may be used to interpret the content of the claims.

Claims (5)

1. A serum endotoxin detection device, characterized in that: it comprises a base (1), the top of the base (1) is connected with a detection box (4), and the top of the detection box (4) is rotatably connected with a cover ( 6), the inside of the detection box (4) is provided with a water bath (12), the bottom of the water bath (12) is provided with a heating device (5), and the inside of the detection box (4) is provided with a detection plate (9) , the detection plate (9) has a test tube hole (11), the two sides of the detection plate (9) are rotatably connected with a lifting plate (2), and the bottom of the lifting plate (2) is connected with a hydraulic rod (15), The free end of the hydraulic rod (15) is connected to the detection box (4), the base (1) is provided with a socket, and the socket is connected to a power supply, and the front of the base (1) is provided with a control panel (3 ), the control panel (3) is provided with a digital display thermometer (301), the control panel (3) is provided with a temperature adjustment knob (305), and the temperature adjustment knob (305) is connected with the heating device (5) It is electrically connected, the control panel (3) is provided with a power switch (307), and the control panel (3) is also provided with a hydraulic lever control switch, and the hydraulic lever control switch includes a pause switch (302), a lift switch (303) and a down switch (304), the pause switch (302), the up switch (303) and the down switch (304) are all electrically connected to the hydraulic rod (15). 2. a kind of serum endotoxin detection device according to claim 1, is characterized in that: described test tube hole (11) is provided with test tube clamping device, and described test tube clamping device comprises arc clamp (16), and the Described arc clip (16) is positioned at the inside of test tube hole (11), and described arc clip (16) is connected with connecting rod (17), and described detection board (9) has spring hole (14), and described spring The hole (14) is connected with a spring (18), and the connecting rod (17) passes through the spring hole (14) and is connected with the free end of the spring (18). 3. A serum endotoxin detection device according to claim 1, characterized in that: an LED light (8) is provided inside the cover (6), and a light switch (306) is provided on the control panel (3) ), the light switch (306) is electrically connected to the LED light (8). 4. A serum endotoxin detection device according to claim 1, characterized in that: the detection board (9) is provided with a handle (10), and the detection box (4) is provided with a recovery tank (13) inside , the recovery tank (13) is used to recover the samples that do not form gel in the test tube. 5. A serum endotoxin detection device according to claim 1, characterized in that: the cover (6) is provided with buckles (7).

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