CN218539693U - Pressure control assembly and biochemical detection device - Google Patents
Pressure control assembly and biochemical detection device Download PDFInfo
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- CN218539693U CN218539693U CN202222508324.9U CN202222508324U CN218539693U CN 218539693 U CN218539693 U CN 218539693U CN 202222508324 U CN202222508324 U CN 202222508324U CN 218539693 U CN218539693 U CN 218539693U
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Abstract
The utility model provides a pressure control subassembly and biochemical detection device belongs to biochemical detection technical field. The pressure control assembly is used for controlling air pressure in a fluid channel of the microfluidic device and comprises an air pump and a plurality of vent pipes, the vent pipes are all communicated with the air pump, and the air pump is used for applying air pressure to the fluid channel through the vent pipes. The pressure control assembly applies air pressure to the micro-fluidic device through the air pump and the vent pipe, and the air pressure is used for accelerating the flow of the detection solution in the fluid channel of the micro-fluidic device, so that the flow speed of the detection solution is increased, the biochemical reaction of the detection solution in the micro-fluidic device is accelerated, and the detection efficiency is improved.
Description
The present application claims priority from chinese patent application 202211042982.1, filed 29/08/2022. The present application refers to the above-mentioned chinese patent application in its entirety.
Technical Field
The utility model relates to a biochemical detection technology field, in particular to pressure control subassembly and biochemical detection device.
Background
In various molecular biology scientific research and clinical medicine molecular diagnosis, a biochemical sample is usually collected in a biochemical sample device, and then the biochemical sample device is arranged in a biochemical detection device for biochemical detection. For example, chinese patent application No. 202010628434.1 discloses a microfluidic device and a method for extracting nucleic acid from a biological sample, and the microfluidic device is a biochemical sample device, which realizes connection and disconnection of fluid channels therein by changing relative positions of subcomponents included therein, and finally realizes extraction of nucleic acid from a biological sample. However, the flow of the detection solution in the fluid channel of the microfluidic device is slow, resulting in low detection efficiency.
SUMMERY OF THE UTILITY MODEL
The to-be-solved technical problem of the utility model is to provide a pressure control subassembly and biochemical detection device in order to overcome the defect that the detection solution circulation speed in micro-fluidic device's the fluid passage among the prior art is slow, detection efficiency is low.
The utility model discloses an above-mentioned technical problem is solved through following technical scheme:
the pressure control assembly comprises an air pump and a plurality of vent pipes, the vent pipes are communicated with the air pump, and the air pump is used for applying air pressure to the fluid channel through the vent pipes.
In the scheme, the pressure control assembly applies air pressure to the micro-fluidic device through the air pump and the vent pipe, and the air pressure is used for accelerating the flow of the detection solution in the fluid channel of the micro-fluidic device, so that the flow speed of the detection solution is increased, the biochemical reaction of the detection solution in the micro-fluidic device is accelerated, and the detection efficiency is improved.
Preferably, the air pressure applied to the fluid channel by the air pump is positive air pressure or negative air pressure.
In the scheme, when the air pump applies positive air pressure to the fluid channel, the positive pressure air flows into the fluid channel of the microfluidic device through the vent pipe, so that the flow of the detection solution in the fluid channel is accelerated; when the air pump applies negative air pressure to the fluid channel, air in the fluid channel of the microfluidic device flows into the vent pipe, and then the flow of the detection solution in the fluid channel is accelerated.
Preferably, the pressure control assembly further comprises a vent head in communication with the vent tube, the vent head for applying air pressure to the fluid passage.
In this scheme, the setting of ventilation head conveniently aims at micro-fluidic device's fluid channel for the direction of applying of atmospheric pressure can be more accurate.
Preferably, the diameter of the end of the aeration head, which is communicated with the aeration pipe, is smaller than the diameter of the end of the aeration head, which is opened towards the fluid channel.
In the scheme, the structure is arranged so that when the air pump introduces positive pressure air into the fluid channel, the air flowing into the fluid channel from the air vent head is buffered, and the air pressure is not too large.
Preferably, the material of the ventilation head is silica gel.
In the scheme, the silica gel has excellent aging resistance, chemical stability, oxidation resistance, weather resistance and high and low temperature resistance, is non-toxic and odorless, and is safer and more durable in use.
Preferably, the pressure control assembly further comprises a hose connector, and two ends of the hose connector are respectively communicated with the vent pipe and the vent head.
In this scheme, hose nipple's pliability is better, can make things convenient for the direction location of ventilation head. So that the venting head can be more accurately aligned with the fluid channel.
Preferably, the air pump is a miniature diaphragm pump.
In this scheme, miniature diaphragm pump removes with simple to operate, the noise is low, corrosion-resistant, pressure is high, is favorable to improving the durability in use of pressure control subassembly.
A biochemical detection device comprises the pressure control assembly.
In the scheme, the biochemical detection device applies air pressure to the microfluidic device through the pressure control assembly, and the air pressure is used for accelerating the flow of the detection solution in the fluid channel of the microfluidic device, so that the flow speed of the detection solution is increased, the biochemical reaction of the detection solution in the microfluidic device is accelerated, and the detection efficiency is improved.
Preferably, the biochemical detection device comprises a holding tank for holding the microfluidic device, and the vent holes of the vent pipes are distributed on the bottom surface and/or the side surface of the holding tank.
In this scheme, the holding tank is favorable to spacing micro-fluidic device, and the blow vent of breather pipe distributes in the bottom surface and the side of holding tank, and the arrangement is nimble various, can with the fluid passage's of micro-fluidic device arrange the phase-match, improves the flow speed of detecting solution, and then improves detection efficiency.
Preferably, the pressure control assembly includes a vent head communicated with the vent pipe, the receiving groove has a through hole corresponding to the vent head, the vent head passes through the through hole, and an opening of the vent head faces to the inside of the receiving groove.
In this scheme, the head of ventilating passes the through-hole entering holding tank's of holding tank inside, makes things convenient for the opening of head of ventilating and micro-fluidic device's fluid passage phase-match, and then applys atmospheric pressure to fluid passage.
The utility model discloses an actively advance the effect and lie in:
the utility model discloses in, pressure control subassembly passes through air pump and breather pipe and applys atmospheric pressure to micro-fluidic device, utilizes the flow of the detection solution in the fluid passage of atmospheric pressure acceleration micro-fluidic device, and then improves the flow rate of detection solution for the biochemical reaction of the detection solution in the micro-fluidic device improves detection efficiency.
Drawings
Fig. 1 is a schematic perspective view of a pressure control assembly according to an embodiment of the present invention.
Fig. 2 is a schematic perspective view of an embodiment of the present invention.
Fig. 3 is a schematic cross-sectional view of an embodiment of the ventilation head and the hose connector of the present invention.
Fig. 4 is a schematic perspective view of a biochemical detection device according to an embodiment of the present invention.
Fig. 5 is a schematic perspective view of a biochemical detection apparatus (with a frame hidden) according to an embodiment of the present invention.
Fig. 6 is a schematic perspective view of another angle of the biochemical detection device (with the frame hidden) according to an embodiment of the present invention.
Description of reference numerals:
Breather pipe 2
Trough 202
Accommodating groove 2021
Detailed Description
The present invention will be more clearly and completely described below by way of examples and with reference to the accompanying drawings, but the present invention is not limited thereto.
As shown in fig. 1 to 6, the present embodiment provides a pressure control assembly 100 and a biochemical detection device 200 including the pressure control assembly 100, in which the biochemical detection device 200 applies air pressure to a microfluidic device through the pressure control assembly 100, and accelerates the flow of a detection solution in a fluid channel of the microfluidic device by using the air pressure, thereby accelerating a biochemical reaction of the detection solution in the microfluidic device and improving the detection efficiency. The microfluidic device is a biochemical sample device, and the connection and disconnection of the fluid channel inside the microfluidic device are realized by changing the relative positions of the sub-components included in the microfluidic device, so as to finally realize the extraction or detection of the target substance in the biochemical sample, for example, the microfluidic device disclosed in the chinese patent application No. 202010628434.1, but the application of the pressure control assembly 100 and the biochemical detection device 200 in this embodiment is not limited to this microfluidic device.
As shown in fig. 1 to 3, the present embodiment provides a pressure control assembly 100 for controlling air pressure in a fluid channel of a microfluidic device, the pressure control assembly 100 includes an air pump 1 and a plurality of vent pipes 2, the vent pipes 2 are all connected to the air pump 1, and the air pump 1 is configured to apply air pressure to the fluid channel through the vent pipes 2. The pressure control assembly 100 applies air pressure to the microfluidic device through the air pump 1 and the vent pipe 2, and the air pressure is used for accelerating the flow of the detection solution in the fluid channel of the microfluidic device, so that the flow speed of the detection solution is increased, the biochemical reaction of the detection solution in the microfluidic device is accelerated, and the detection efficiency is improved. In particular, in the present embodiment, the pressure control assembly 100 is provided with only one vent pipe 2.
In this embodiment, the air pressure applied to the fluid channel by the air pump 1 is positive air pressure, and the positive air pressure flows into the fluid channel of the microfluidic device through the vent tube 2, so as to accelerate the flow of the detection solution in the fluid channel. In other alternative embodiments, the air pressure applied to the fluid channel by the air pump 1 may also be negative air pressure, and in this case, the air in the fluid channel of the microfluidic device flows into the air pipe 2, so as to accelerate the flow of the detection solution in the fluid channel.
In this embodiment, the pressure control assembly 100 further comprises a vent head 3, the vent head 3 being in communication with the vent tube 2, the vent head 3 being used to apply air pressure to the fluid passage. The arrangement of the vent head 3 is convenient for aligning with a fluid channel of the microfluidic device, so that the applying direction of the air pressure can be more accurate.
In this embodiment, the diameter of the end of the ventilation head 3 communicating with the ventilation tube 2 is smaller than the diameter of the end of the ventilation head 3 opening towards the fluid channel, so that when the air pump 1 injects positive pressure air into the fluid channel, the air flowing into the fluid channel from the ventilation head 3 is buffered, and the air pressure is not too large.
In the present embodiment, the material of the vent head 3 is silicone. The silica gel has excellent aging resistance, chemical stability, oxidation resistance, weather resistance and high and low temperature resistance, is non-toxic and odorless, and the ventilation head 3 is safer and more durable in use due to the adoption of the silica gel material.
In this embodiment, the pressure control assembly 100 further includes a hose connector 4, and both ends of the hose connector 4 are respectively communicated with the vent pipe 2 and the vent head 3. The flexibility of the hose connector 4 is good, and the direction positioning of the ventilation head 3 can be facilitated. So that the aeration head 3 can be more precisely aligned with the fluid channel.
In the present embodiment, the air pump 1 is a micro diaphragm pump. The miniature diaphragm pump is convenient to move and install, low in noise, corrosion resistant, high in pressure, and beneficial to improving the service durability of the pressure control assembly 100.
As shown in fig. 4 to fig. 6, the present embodiment further provides a biochemical detection apparatus 200, wherein the biochemical detection apparatus 200 includes the pressure control assembly 100. The biochemical detection device 200 applies air pressure to the microfluidic device through the pressure control assembly 100, and the air pressure accelerates the flow of the detection solution in the fluid channel of the microfluidic device, so that the flow speed of the detection solution is increased, the biochemical reaction of the detection solution in the microfluidic device is accelerated, and the detection efficiency is improved.
In this embodiment, the biochemical detection device 200 includes a holding tank 2021 for holding the microfluidic device, and a plurality of vents of the vent tube 2 are distributed on the bottom surface of the holding tank 2021. The holding tank 2021 is favorable to spacing the micro-fluidic device, and the blow vent of breather pipe 2 distributes in the bottom surface of holding tank 2021, can with the fluid passage's of micro-fluidic device arrange the phase-match, improves the flow velocity of detecting solution, and then improves detection efficiency. In other alternative embodiments, the vents of the vent tube 2 may also be distributed on the side of the receiving groove 2021, as long as the arrangement of the fluid channels of the microfluidic device can be matched. Specifically, in this embodiment, the biochemical detection apparatus 200 further includes a frame 201 and a tank 202, the pressure control assembly 100 is disposed in the frame 201, the tank 202 is connected to the frame 201, and the tank 2021 is disposed in the tank 202.
In this embodiment, the pressure control assembly 100 includes a vent head 3 communicating with the vent pipe 2, the receiving groove 2021 has a through hole provided corresponding to the vent head 3, the vent head 3 passes through the through hole, and the vent head 3 opens toward the inside of the receiving groove 2021. The vent head 3 penetrates through the through hole of the containing groove 2021 to enter the inside of the containing groove 2021, so that the opening of the vent head 3 is conveniently matched with a fluid channel of the microfluidic device, and further air pressure is applied to the fluid channel.
Although specific embodiments of the present invention have been described above, it will be understood by those skilled in the art that this is by way of example only and that the scope of the invention is defined by the appended claims. Various changes and modifications to these embodiments may be made by those skilled in the art without departing from the spirit and the principles of the present invention, and these changes and modifications are all within the scope of the present invention.
Claims (10)
1. The pressure control assembly is used for controlling air pressure in a fluid channel of a micro-fluidic device and is characterized in that the pressure control assembly comprises an air pump and a plurality of vent pipes, the vent pipes are communicated with the air pump, and the air pump is used for applying air pressure to the fluid channel through the vent pipes.
2. The pressure control assembly of claim 1, wherein the air pressure applied to the fluid passageway by the air pump is positive or negative.
3. The pressure control assembly of claim 1, further comprising a vent head in communication with the vent tube, the vent head for applying air pressure to the fluid passage.
4. The pressure control assembly as claimed in claim 3, wherein the vent head communicates with the vent tube at an end thereof having a smaller diameter than an end of the vent head opening to the fluid passage.
5. The pressure control assembly of claim 3, wherein the material of the venting head is silicone.
6. The pressure control assembly of claim 3, further comprising a hose fitting having ends communicating with the vent tube and the vent head, respectively.
7. A pressure control assembly as claimed in claim 1 wherein the air pump is a miniature diaphragm pump.
8. A biochemical test device, comprising the pressure control assembly of any one of claims 1-7.
9. The biochemical detection device according to claim 8, wherein the biochemical detection device comprises a receiving groove for receiving the microfluidic device, and the plurality of vent holes of the vent tube are distributed on a bottom surface and/or a side surface of the receiving groove.
10. The biochemical detecting apparatus according to claim 9, wherein the pressure control assembly includes a vent head communicating with the vent pipe, the accommodating groove has a through hole provided corresponding to the vent head, the vent head passes through the through hole, and an opening of the vent head faces an inside of the accommodating groove.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211042982 | 2022-08-29 | ||
| CN2022110429821 | 2022-08-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN218539693U true CN218539693U (en) | 2023-02-28 |
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Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211152934.8A Pending CN117660166A (en) | 2022-08-29 | 2022-09-21 | Nucleic acid detection device, nucleic acid detection method, electronic device, and storage medium |
| CN202222508325.3U Active CN218298032U (en) | 2022-08-29 | 2022-09-21 | Optical detection device |
| CN202222505729.7U Active CN218486017U (en) | 2022-08-29 | 2022-09-21 | Heating element and biochemical detection device |
| CN202222505733.3U Active CN218270683U (en) | 2022-08-29 | 2022-09-21 | Driving device with rotation angle measuring function |
| CN202222508324.9U Active CN218539693U (en) | 2022-08-29 | 2022-09-21 | Pressure control assembly and biochemical detection device |
| CN202222505727.8U Active CN218537741U (en) | 2022-08-29 | 2022-09-21 | Containing device with limiting function |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211152934.8A Pending CN117660166A (en) | 2022-08-29 | 2022-09-21 | Nucleic acid detection device, nucleic acid detection method, electronic device, and storage medium |
| CN202222508325.3U Active CN218298032U (en) | 2022-08-29 | 2022-09-21 | Optical detection device |
| CN202222505729.7U Active CN218486017U (en) | 2022-08-29 | 2022-09-21 | Heating element and biochemical detection device |
| CN202222505733.3U Active CN218270683U (en) | 2022-08-29 | 2022-09-21 | Driving device with rotation angle measuring function |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202222505727.8U Active CN218537741U (en) | 2022-08-29 | 2022-09-21 | Containing device with limiting function |
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|---|---|
| CN (6) | CN117660166A (en) |
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2022
- 2022-09-21 CN CN202211152934.8A patent/CN117660166A/en active Pending
- 2022-09-21 CN CN202222508325.3U patent/CN218298032U/en active Active
- 2022-09-21 CN CN202222505729.7U patent/CN218486017U/en active Active
- 2022-09-21 CN CN202222505733.3U patent/CN218270683U/en active Active
- 2022-09-21 CN CN202222508324.9U patent/CN218539693U/en active Active
- 2022-09-21 CN CN202222505727.8U patent/CN218537741U/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN218537741U (en) | 2023-02-28 |
| CN117660166A (en) | 2024-03-08 |
| CN218486017U (en) | 2023-02-17 |
| CN218270683U (en) | 2023-01-10 |
| CN218298032U (en) | 2023-01-13 |
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