CN218496260U - Laser light path inspection device for mass spectrometer - Google Patents

Laser light path inspection device for mass spectrometer Download PDF

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Publication number
CN218496260U
CN218496260U CN202222758570.XU CN202222758570U CN218496260U CN 218496260 U CN218496260 U CN 218496260U CN 202222758570 U CN202222758570 U CN 202222758570U CN 218496260 U CN218496260 U CN 218496260U
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China
Prior art keywords
inspection
light path
fixing piece
laser light
fixing
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赵灵飞
邓申奥
郑君涛
成王军
李康康
蔡克亚
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Autobio Labtec Instruments Zhengzhou Co Ltd
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Autobio Labtec Instruments Zhengzhou Co Ltd
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Abstract

The utility model discloses a laser light path verifying attachment for mass spectrograph, including illuminometer, inspection casing, positioning unit, fixed unit and linkage unit, positioning unit has the constant head tank that sets up on the diapire upper surface of inspection casing and sets up the first side exit on the inspection casing lateral wall, and first side exit communicates with the constant head tank; the fixing unit is provided with a first fixing piece for fixing the micro-coke energy meter, and the first fixing piece enters and exits the positioning groove through the first side inlet and outlet; the connecting unit fixes the first fixing piece or the illuminometer in the positioning groove. The illuminometer and the micro-coke energy meter of the utility model can enter and exit the inspection shell through the first side inlet and outlet; the ion source provided with the laser light path system is fixed at the upper opening of the inspection shell and forms an inspection chamber with the inspection shell in a surrounding mode, laser energy and illumination of the laser light path system are respectively and rapidly inspected through the illuminometer and the micro-focus energy meter, only light path components need to be replaced during testing, and integral disassembly and repeated time drawing are not needed.

Description

Laser light path inspection device for mass spectrometer
Technical Field
The utility model belongs to the technical field of the check-up technique of mass spectrograph light path and specifically relates to a laser light path verifying attachment for mass spectrograph is related to.
Background
An ionization-time of flight mass spectrometer (MALDI-TOF-MS for short) based on auxiliary laser desorption is an important branch of a mass spectrometer family, and is characterized in that a sample is irradiated by laser and forms a cocrystallized film with a matrix, the matrix absorbs energy from the laser and transfers the energy to biomolecules, and the protons are transferred to the biomolecules or obtained from the biomolecules in the ionization process, so that the biomolecules are ionized.
For MALDI-TOF-MS, a laser optical path system is an important factor influencing the identification result of mass spectrum. The existing mass spectrometer is used for testing a lens light path part, namely a lens module is arranged in a mass spectrum detection system for complete machine test, and whether the laser energy and the illuminance can meet the ionization requirements of microorganisms is tested. However, by adopting a complete machine inspection mode, once parameters are abnormal or have faults, air needs to be sent into the vacuum chamber to enable the vacuum chamber to recover normal pressure, then the laser module is detached from the mass spectrum detection system, the optical path devices are replaced one by one, and the vacuum pumping inspection is carried out again until the test is qualified. The following problems exist in actual production:
firstly, key parameters such as laser energy, illuminance and the like cannot be obtained in advance by adopting the method, and the direction causing abnormal problems or faults cannot be accurately and quickly determined;
secondly, the components in the laser optical path system need to be replaced one by one for testing in the detection process, vacuumizing needs to be performed again for each test, time and labor are wasted, manpower is wasted, the working efficiency is low, and the batch evaluation and inspection requirements of the components in the laser optical path system cannot be met; in addition, the mass spectrometer needs laser energy and illuminance data to judge the fault reason and the result after maintenance in the client field maintenance, and the installation instrument is repeatedly vacuumized during testing, thereby slowing the maintenance efficiency and failing to realize the rapid use of the mass spectrometer.
Moreover, the laser optical path system is arranged in a microbial mass spectrum detection system for testing, is limited to specific equipment and working conditions, and has poor universality.
In conclusion, how to design a portable inspection device which can quickly inspect the performance of each component in a laser optical path system and meet the requirement of batch test evaluation is important for inspecting a mass spectrometer optical path module.
Disclosure of Invention
In view of this, the utility model provides a laser light path verifying attachment for mass spectrograph need not to relapse the evacuation, has improved the inspection efficiency of mass spectrograph laser light path.
In order to realize the purpose, the invention adopts the following technical scheme:
the invention relates to a laser light path inspection device for a mass spectrometer, which comprises an illuminometer; also comprises
An inspection housing enclosing an inspection chamber with an ion source;
the positioning unit is provided with a positioning groove formed in the upper surface of the bottom wall of the inspection shell and a first side inlet and outlet formed in the side wall of the inspection shell, and the first side inlet and outlet is communicated with the positioning groove;
the fixing unit is provided with a first fixing piece for fixing the micro-coke energy meter, and the first fixing piece enters and exits the positioning groove through the first side inlet and outlet; and
and the connecting unit is arranged on the side wall of the checking shell and fixes the first fixing piece or the illuminometer in the positioning groove.
In the scheme, the illuminometer and the first fixing piece fixed with the micro-focus energy meter can enter and exit the inspection shell through the first side inlet and outlet; the ion source provided with the laser light path system is fixed at the upper opening of the inspection shell and forms an inspection cavity with the inspection shell, laser energy and illuminance of the laser light path system are rapidly inspected through the illuminometer and the micro-focus energy score, only light path components need to be replaced when replaced, time is not required to be wholly disassembled and repeatedly taken out, rapid testing of each component in the laser light path system of the mass spectrometer is improved, working efficiency is high, rapid inspection requirements of batch components can be met, and manual labor is saved. Additionally, the utility model discloses simple structure, small in size conveniently carries, can satisfy the user demand in different workshops or laboratories.
In a preferred embodiment of the present invention, the connection unit includes a plurality of fastening screws screwed on the side wall of the inspection housing. When the device is actually installed, the fastening screws can be arranged on a pair of side walls of the inspection shell, and also can be installed on the bottom wall of the inspection shell, so that the fixing effect of the illuminometer and the first fixing piece is ensured, and the interference of vibration factors on laser energy and illuminance is reduced.
In another preferred embodiment of the present invention, the connection unit includes a plurality of spring positioning columns fixed on the side wall of the inspection casing, and the side surface of the first fixing member has positioning holes engaged with the spring positioning columns. When the spring positioning column is actually installed, the end part of the spring positioning column is clamped in the positioning hole, so that the first fixing piece can be fixed on the inspection shell, and the reliability of laser energy parameters is ensured.
In a preferred embodiment of the present invention, one end of the first fixing member has a mounting groove for fitting the micro-focus energy meter, and the upper surface of the first fixing member has a wire guide communicating with the mounting groove. More preferably, the installation groove is an arc groove, and the wire guide groove is of a strip structure. The mounting groove is processed into an arc groove, so that the fixing requirement of the micro-coke energy meter with a circular structure can be met; the upper surface of the first fixing piece is provided with a wire groove communicated with the arc groove, so that a connecting wire of the energy meter can be conveniently led out, and wiring is convenient.
In another preferred embodiment of the present invention, a position-limiting slot matched with the micro-focus energy meter is disposed in the middle of the upper surface of the first fixing member, the position-limiting slot is disposed along the length direction of the first fixing member, and a concave surface is further disposed at one end of the first fixing member. More preferably, the limiting clamping groove is of a strip-shaped structure. In this additional scheme, spacing draw-in groove can satisfy the fixed demand of rectangular shape little burnt energy meter, and concave plane highly is less than the height of first mounting upper surface, the wiring of being convenient for.
In another preferred embodiment of the present invention, the fixing unit further includes a second fixing member for fixing the illuminometer. When the illumination meter is actually installed, the illumination meter can be fixed through the second fixing piece, and the second fixing piece is fixed in the positioning groove during use. Of course, the illuminometer can be directly fixed on the positioning groove, and the flexible fixation of the illuminometer is realized.
In a more preferred embodiment of the present invention, the first fixing member and the second fixing member are an integral structure, and the second side inlet and outlet are formed on the other side wall of the inspection casing opposite to the first side inlet and outlet. When the device is used, the two ends of the fixing unit extend out of the first side inlet and the second side outlet, and the positions of the illuminometer and the micro-focus energy meter can be adjusted only by adjusting the positions of the first fixing piece and the second fixing piece, so that the inspection requirements of different inspection items are met.
Compared with the prior art, the utility model has the advantages of it is following:
the illuminometer and the first fixing piece fixed with the micro-coke energy meter in the utility model can enter and exit the inspection shell through the first side inlet and outlet; the ion source provided with the laser light path system is fixed at the upper opening of the inspection shell and forms an inspection chamber with the inspection shell in a surrounding mode, laser energy and illumination of the laser light path system are respectively and rapidly inspected through the illuminometer and the micro-focus energy meter, only light path components need to be replaced when replaced, time is not required to be integrally disassembled and repeatedly taken out, and rapid inspection of the laser light path system of the mass spectrometer is improved.
Drawings
Fig. 1 is a schematic view of a first embodiment of the present invention (with a light meter installed in the inspection casing).
Fig. 2 is a side view of the first embodiment.
Fig. 3 is a schematic structural view of a first fixing jig in the first embodiment.
Fig. 4 is another schematic view of the first fixing jig in the first embodiment.
Fig. 5 is another schematic view of the connection unit in the first embodiment.
Fig. 6 is a diagram showing a state of use in the first embodiment (the first fixing jig is attached to the inspection case).
Fig. 7 is a schematic structural view of the second embodiment.
Fig. 8 is a schematic structural view of a fixing unit in the third embodiment.
Fig. 9 is a use state diagram of the third embodiment.
Fig. 10 is another usage state diagram of the third embodiment.
Detailed Description
The following describes embodiments of the present invention in detail with reference to the accompanying drawings, which are implemented on the premise of the technical solution of the present invention, and give detailed implementation manners and specific operation procedures, but the scope of the present invention is not limited to the following embodiments.
In the following embodiments, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" when they are used are to be construed broadly, e.g., as being fixed or removable or integral; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood by those skilled in the art from the specific situation.
In addition, it should be noted that in the following description of the embodiments, the terms "front", "back", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of describing the present invention and simplifying the description, but do not indicate or imply that the referred device or element must have a specific orientation, be configured in a specific orientation, and operate, and thus, should not be construed as limiting the present invention.
Implementation mode one
As can be seen from fig. 1-2, the laser light path inspection device for a mass spectrometer according to the present embodiment includes an illuminometer 1 (preferably, a digital display illuminometer), an inspection housing 2, a positioning unit, a fixing unit, and a connecting unit; the inspection shell 2 is provided with an inspection groove 1.1 (with an upper opening) in a circular structure, and the inspection shell 2 and the ion source F enclose an inspection chamber;
the positioning unit is provided with a positioning groove 3 arranged on the upper surface of the bottom wall of the inspection shell 2 and a first side inlet and outlet 4 arranged on the side wall of the inspection shell 2, and the first side inlet and outlet 4 is communicated with the positioning groove 3;
the fixing unit is provided with a first fixing piece (namely a first fixing clamp 6) for fixing a micro-focus energy meter 5 (the energy meter is preferably a digital display type energy meter), and the first fixing clamp 6 enters and exits the positioning groove 3 through a first side inlet and outlet 4; the connecting unit is arranged on the side wall of the inspection shell 2 and fixes the first fixing clamp 6 or the illuminometer 1 in the positioning groove 3;
when the device is used, the illuminometer 1 enters the positioning groove 3 from the first side inlet/outlet 4, the illuminometer 1 is fixed in the positioning groove 3 by the connecting unit, and the illuminometer 1 is opposite to the ion source up and down, so that the rapid test of illuminance can be realized; after the illuminance test is completed, the illuminometer 1 is taken out and then the first fixing clamp 6 is fixed in the positioning groove 3, so that the testing part of the micro-focus energy meter 5 is positioned under the ion source, the rapid test of the laser energy is realized, repeated disassembly and vacuumizing are not needed at all, only optical components in the ion source need to be replaced, the testing efficiency of each optical component in a laser light path is improved, and the testing requirements of batch components can be met. In addition, the inspection casing 2 is small in size and convenient to carry.
As shown in fig. 1, the connection unit includes a plurality of fastening screws 7 screwed on the bottom wall of the inspection case 2, and the illuminometer 1 and the first fixing jig 6 are respectively fixed in the positioning groove 3 by the fastening screws 7, so as to reduce interference of external factors such as vibration during the test process to the test.
In actual installation, the fastening screws 7 may also be screwed on a pair of side walls of the inspection housing 2 to realize the limiting and fixing of the two side surfaces of the first fixing block, as shown in fig. 5.
The utility model discloses a first mounting fixture 6 not only can be used to fixed circular shape energy meter, can also be used to fix the energy meter of rectangular shape, and the operator can select according to actual conditions is nimble.
When the energy meter is circular, as shown in fig. 3, one end of the first fixing clamp 6 is provided with an installation groove 6.1 matched with the micro-focus energy meter 5, and the installation groove 6.1 is an arc groove to meet the installation requirement of the circular energy meter; for the convenience draws the connecting wire of energy meter out inspection casing 2, the metallic channel 6.2 of laying along its length direction is seted up to the upper surface of first mounting fixture 6, and metallic channel 6.2 is the bar structure and is located the middle part of first mounting fixture 6 upper surface, can draw out inspection casing 2 with the connecting wire of energy meter, and the structure is ingenious. In addition, the other end of the first fixing jig 6 extends out of the inspection case 2, facilitating insertion and removal.
When the energy meter is in a long strip structure, as shown in fig. 4, the upper surface of the first fixing clamp 6 is provided with a limiting clamping groove 6.3 which is matched with the strip energy meter and is in a long strip structure, the limiting clamping groove 6.3 is formed along the length direction of the first fixing piece, the energy meter is clamped in the limiting clamping groove 6.3 during installation, and then the energy meter is fixed in the limiting clamping groove 6.3 through a screw. In addition, one end part (located at the outer side of the inspection shell 2) of the first fixing clamp 6 is also provided with a concave plane 6.4, and the height of the concave plane 6.4 is lower than that of the upper surface of the first fixing clamp 6, so that a connecting wire can conveniently pass through, and the connecting wire can be conveniently inserted and pulled out.
In practical use, an operator can flexibly select a proper fixing clamp according to the type of the energy meter.
The application process of the embodiment is as follows: as shown in fig. 6, the ion source F is fixed at the upper opening of the inspection casing 2, and the laser light path is ensured to cover the inner surface of the bottom wall of the inspection casing 2;
when testing the influence of components and parts in the laser light path to illuminance, insert illuminometer 1 in constant head tank 3 and then fix with fastening screw 7 can. During the test process, the illuminance can be rapidly read;
when the influence of components on the laser energy needs to be tested, the first fixing clamp 6 is inserted into the positioning groove 3 and fixed by the fastening screw 7, so that the laser energy can be quickly tested;
the test process only needs to replace the light path components and the test pieces in the ion source, the repeated vacuum pumping is not needed, the detection efficiency is improved, and the rapid test requirement of mass light path components can be met.
Second embodiment
The present embodiment differs from the first embodiment only in the structure of the connecting means: as can be seen from fig. 7, the connection unit in this embodiment includes a pair of spring positioning posts 8 fixed on a pair of side walls of the inspection housing 2, and a pair of side walls of the first fixing jig 6 is provided with positioning holes for engaging with the spring positioning posts 8. When the laser energy parameter fixing device is used, the end part of the spring positioning column 8 is clamped in the positioning hole, so that the first fixing clamp 6 can be fixed, and the reliability of laser energy parameters is ensured.
Third embodiment
The utility model discloses the difference with embodiment one lies in the structure of fixed unit different: as shown in fig. 8, the fixing unit further includes a second fixing member (i.e., a second fixing jig 9) for fixing the illuminance meter 1, and the second fixing jig 9 and the first fixing jig 6 are of an integrated structure. Correspondingly, due to the length and the length of the first fixing clamp 6 and the second fixing clamp 9, a second side access opposite to the first side access 4 is formed on the side wall of the inspection shell 2.
When in use, the first fixing clamp 6 can be inserted into the positioning groove 3 to enable the micro-focus energy meter 5 to be positioned below the ion source, as shown in fig. 9; after the test is completed, the second fixture 9 is snapped into the inspection housing 2 so that the illuminometer 1 is positioned below the ion source, as shown in particular in fig. 10.
Certainly, during actual test, the illuminometer 1 on the second fixing clamp 9 can be installed below the ion source, then the micro-focus energy meter 5 is arranged below the ion source, the positions of the illuminometer 1 and the micro-focus energy meter 5 can be adjusted only by adjusting the positions of the first fixing piece and the second fixing piece, the inspection requirements of different test items are met, and the operation is simple and convenient.
Finally, it should be emphasized that the above-described embodiments are merely preferred embodiments of the present invention, and not limitative of the present invention, and although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications and equivalents may be made to the embodiments described in the foregoing without inventive faculty, or that equivalents may be substituted for elements thereof. Therefore, any modification, equivalent replacement, improvement and the like made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (9)

1. A laser light path verifying attachment for mass spectrograph which characterized in that: comprises an illuminometer;
an inspection housing enclosing an inspection chamber with an ion source;
the positioning unit is provided with a positioning groove formed in the upper surface of the bottom wall of the inspection shell and a first side inlet and outlet formed in the side wall of the inspection shell, and the first side inlet and outlet are communicated with the positioning groove;
the fixing unit is provided with a first fixing piece for fixing the micro-focus energy meter, and the first fixing piece enters and exits the positioning groove through the first side inlet/outlet; and
and the connecting unit is arranged on the side wall of the checking shell and fixes the first fixing piece or the illuminometer in the positioning groove.
2. The laser light path inspection device for a mass spectrometer according to claim 1, characterized in that: the connection unit includes a plurality of fastening screws screwed to a sidewall of the inspection case.
3. The laser light path inspection device for a mass spectrometer of claim 1, wherein: the connecting unit comprises a plurality of spring positioning columns fixed on the side wall of the inspection shell, and positioning holes matched with the spring positioning columns are formed in the side face of the first fixing piece.
4. The laser light path inspection device for a mass spectrometer according to claim 2 or 3, characterized in that: one end of the first fixing piece is provided with a mounting groove matched with the micro-focus energy meter, and the upper surface of the first fixing piece is provided with a wire guide groove communicated with the mounting groove.
5. The laser light path inspection device for a mass spectrometer according to claim 4, characterized in that: the mounting groove is an arc groove, and the wire groove is of a strip-shaped structure.
6. The laser light path inspection device for a mass spectrometer according to claim 2 or 3, characterized in that: the middle part of the upper surface of the first fixing piece is provided with a limiting clamping groove matched with the micro-focus energy meter, the limiting clamping groove is formed along the length direction of the first fixing piece, and a concave plane is further formed in one end part of the first fixing piece.
7. The laser light path inspection device for a mass spectrometer according to claim 6, characterized in that: the limiting clamping groove is of a strip-shaped structure.
8. The laser light path inspection device for a mass spectrometer according to claim 1, characterized in that: the fixing unit further comprises a second fixing piece for fixing the illuminometer.
9. The laser light path inspection device for a mass spectrometer of claim 8, wherein: the first fixing piece and the second fixing piece are of an integrated structure, and a second side inlet and a second side outlet are formed in the other side wall of the inspection shell, which is opposite to the first side inlet and outlet row.
CN202222758570.XU 2022-10-20 2022-10-20 Laser light path inspection device for mass spectrometer Active CN218496260U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202222758570.XU CN218496260U (en) 2022-10-20 2022-10-20 Laser light path inspection device for mass spectrometer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202222758570.XU CN218496260U (en) 2022-10-20 2022-10-20 Laser light path inspection device for mass spectrometer

Publications (1)

Publication Number Publication Date
CN218496260U true CN218496260U (en) 2023-02-17

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ID=85193916

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Application Number Title Priority Date Filing Date
CN202222758570.XU Active CN218496260U (en) 2022-10-20 2022-10-20 Laser light path inspection device for mass spectrometer

Country Status (1)

Country Link
CN (1) CN218496260U (en)

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