CN218470748U

CN218470748U - Structure for microfluidic immunofluorescence detection device

Info

Publication number: CN218470748U
Application number: CN202222765501.1U
Authority: CN
Inventors: 陈坦; 彭绍铁; 杨健康
Original assignee: Wuhan Xinsheng Biotechnology Co ltd
Current assignee: Wuhan Xinsheng Biotechnology Co ltd
Priority date: 2022-10-20
Filing date: 2022-10-20
Publication date: 2023-02-10
Anticipated expiration: 2032-10-20

Abstract

The utility model discloses a structure for a microfluidic immunofluorescence detection device, which comprises a base, a connecting block, a mounting groove, a sliding groove, a first blocking piece, a first through hole, a first threaded hole, a first holding tank, a second holding tank, a spring plate, a second through hole, a second threaded hole, a position switch, a sliding block, a sliding strip, a rack, a third through hole, a third threaded hole, a second blocking piece, a mounting seat, a motor, a gear and a fourth threaded hole; sliding grooves are formed in the inner walls of the two sides of the mounting groove, sliding strips are fixedly connected to the outer walls of the two sides of the sliding block, and the sliding strips are connected into the sliding grooves in a sliding mode; the utility model fixes the reagent strip by the elasticity of the elastic sheet, which not only ensures the stability of the detection process, but also has simple operation and convenient taking and placing; the utility model discloses a gear drive rack to realize that detecting instrument's automation comes and goes, compare current lead screw drive, the structure is more compact, has that stability is good, the noise is little, advantage with low costs.

Description

Structure for microfluidic immunofluorescence detection device

Technical Field

The utility model relates to an in vitro diagnosis technical field, in particular to a structure for micro-fluidic immunofluorescence detection device.

Background

The immunofluorescence detection technology is a rapid detection technology commonly used in biological detection at present, and has the main advantages of strong specificity, high sensitivity, high speed and the like. The basic principle is that fluorescent substance is used as a marker, and the sensitivity and the detectability of fluorescence are combined with the high specificity reaction of antigen and antibody. The specific fluorescence can be directly observed by a fluorescence microscope, or can be received by a photoelectric converter and converted into an electric signal for further processing. Since immunofluorescence assay can accurately, sensitively and rapidly locate and detect some trace substances, immunofluorescence technology has been widely applied in many aspects such as immunology, microbiology, pathology, oncology and clinical examination. When the existing immunofluorescence detection device is used, the following defects exist: firstly, a reagent strip fixing mechanism is lacked, so that the stability is lacked when the reagent strip fixing mechanism is used; secondly, in order to realize the automation of the detection process, the existing detection device is designed with a driving mechanism for driving a bearing mechanism of a reagent strip or a detection instrument, and in order to ensure the precision and the stability of the device, the existing driving mechanism is realized by combining a motor and a screw rod, but the design can lead to the incompact structure of the device, so that the volume of the device is increased, and the cost is higher.

SUMMERY OF THE UTILITY MODEL

The utility model aims at providing a structure for micro-fluidic immunofluorescence detection device to solve the problem that proposes among the above-mentioned background art.

In order to solve the technical problem, the utility model provides a following technical scheme: the utility model provides a structure for micro-fluidic immunofluorescence detection device, the on-line screen storage device comprises a base, the mounting groove has been seted up to the upper surface of base, sliding connection has the slider in the mounting groove, first holding tank has been seted up in the mounting groove, the both sides of first holding tank are provided with first separation blade, and in first separation blade screwed fixation in the mounting groove, the second holding tank has been seted up in the first holding tank, the silk is fixed with the shell fragment in the second holding tank, the last surface mounting of base has the mount pad, the last fixed surface of mount pad is connected with the motor, the output fixedly connected with gear of motor, one side meshing of gear is connected with the rack, and rack screwed fixation is on the slider.

Preferably, the sliding grooves are formed in the inner walls of the two sides of the mounting groove, sliding strips are fixedly connected to the outer walls of the two sides of the sliding block, and the sliding strips are connected to the sliding grooves in a sliding mode.

Preferably, a position switch is fixed on the outer wall of one side of the base through screws, and a second blocking piece is fixed on the outer wall of one side of the sliding block through screws at a position corresponding to the position switch.

Preferably, the upper surface fixed connection of base has the connecting block, and connecting block screw fixation is on the mount pad.

Preferably, a first through hole is formed in the first blocking piece, a first threaded hole is formed in the position, corresponding to the first through hole, on the inner wall of the mounting groove, a second through hole is formed in the elastic piece, a second threaded hole is formed in the position, corresponding to the second through hole, on the inner wall of the second accommodating groove, a third through hole is formed in the rack, a third threaded hole is formed in the position, corresponding to the third through hole, on the upper surface of the sliding block, and a fourth threaded hole is formed in the outer wall of the gear.

Compared with the prior art, the utility model discloses the beneficial effect who reaches is: the utility model fixes the reagent strip by the elasticity of the elastic sheet, which not only ensures the stability of the detection process, but also has simple operation and convenient taking and placing; the utility model discloses a gear drive rack to realize that detecting instrument's automation comes and goes, compare current lead screw drive, the structure is more compact, has that stability is good, the noise is little, advantage with low costs.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.

Fig. 1 is a schematic view of the overall three-dimensional structure of the present invention;

FIG. 2 is an exploded view of the overall structure of the present invention;

in the figure: 1. a base; 10. connecting blocks; 11. mounting grooves; 12. a chute; 13. a first baffle plate; 14. a first through hole; 15. a first threaded hole; 16. a first accommodating groove; 17. a second accommodating groove; 18. a spring plate; 19. a second through hole; 110. a second threaded hole; 111. a position switch; 2. a slider; 20. a slide bar; 21. a rack; 22. a third through hole; 23. a third threaded hole; 24. a second baffle plate; 3. a mounting seat; 30. a motor; 31. a gear; 32. and a fourth threaded hole.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by a person of ordinary skill in the art without creative efforts belong to the protection scope of the present invention.

Referring to fig. 1-2, the present invention provides an embodiment: a structure for a microfluidic immunofluorescence detection device comprises a base 1, wherein an installation groove 11 is formed in the upper surface of the base 1, a sliding block 2 is connected in the installation groove 11 in a sliding mode, a first accommodating groove 16 is formed in the installation groove 11, first blocking pieces 13 are arranged on two sides of the first accommodating groove 16, the first blocking pieces 13 are fixed in the installation groove 11 through screws, a second accommodating groove 17 is formed in the first accommodating groove 16, elastic pieces 18 are fixed on screws in the second accommodating groove 17, an installation seat 3 is installed on the upper surface of the base 1, a motor 30 is fixedly connected to the upper surface of the installation seat 3, a gear 31 is fixedly connected to the output end of the motor 30, a rack 21 is connected to one side of the gear 31 in a meshed mode, and the rack 21 is fixed on the sliding block 2 through screws; the inner walls of two sides of the mounting groove 11 are provided with sliding grooves 12, the outer walls of two sides of the sliding block 2 are fixedly connected with sliding strips 20, and the sliding strips 20 are connected in the sliding grooves 12 in a sliding manner; a position switch 111 is fixed on the outer wall of one side of the base 1 through screws, and a second baffle 24 is fixed on the outer wall of one side of the sliding block 2 through screws at a position corresponding to the position switch 111; the upper surface of the base 1 is fixedly connected with a connecting block 10, and the connecting block 10 is fixed on the mounting base 3 through screws; first through hole 14 has been seted up on first separation blade 13, first screw hole 15 has been seted up to the position department that corresponds first through hole 14 on the inner wall of mounting groove 11, second through hole 19 has been seted up on shell fragment 18, second screw hole 110 has been seted up to the position department that corresponds second through hole 19 on the inner wall of second holding tank 17, third through hole 22 has been seted up on rack 21, third screw hole 23 has been seted up to the position department that corresponds third through hole 22 to the upper surface of slider 2, fourth screw hole 32 has been seted up on the outer wall of gear 31.

The working principle is as follows: use the utility model discloses when carrying out the reagent strip and detecting, through staff or robotic arm, aim at the reagent strip first holding tank 16 and fill in to end, shell fragment 18 is impressed in second holding tank 17, provide ascending thrust to the reagent strip, the reagent strip is blocked by first separation blade 13 in mounting groove 11 simultaneously, thereby keep the stationary state, start motor 30 on mount pad 3, drive gear 31 and rotate, gear 31 drives slider 2 through rack 21, slider 2 slides along spout 12 through draw runner 20, the detecting instrument on slider 2 moves to the reagent strip detection position thereupon, motor 30 stops, the detecting instrument detects the reagent strip, after accomplishing the detection, motor 30 reverses, drive slider 2 and reset, until position switch 111 senses second separation blade 24, motor 30 stops; the base 1 and the connecting block 10 are of an integrated structure, the connecting block 10 is used for installing the mounting base 3, the first through hole 14, the first threaded hole 15, the second through hole 19, the second threaded hole 110, the third through hole 22 and the third threaded hole 23 are used for installing screws, and the fourth threaded hole 32 is used for installing a jackscrew.

In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected" and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

The above-described embodiments of the apparatus are merely illustrative, and the units described as separate parts may or may not be physically separate, and parts displayed as units may or may not be physical units, may be located in one position, or may be distributed on multiple network units. Some or all of the modules may be selected according to actual needs to achieve the purpose of the solution of this embodiment. One of ordinary skill in the art can understand and implement it without inventive effort.

Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention in its corresponding aspects.

Claims

1. A structure for microfluidic immunofluorescence detection devices, comprising a base (1), characterized in that: mounting groove (11) have been seted up to the upper surface of base (1), sliding connection has slider (2) in mounting groove (11), first holding tank (16) have been seted up in mounting groove (11), the both sides of first holding tank (16) are provided with first separation blade (13), and first separation blade (13) screw fixation is in mounting groove (11), second holding tank (17) have been seted up in first holding tank (16), the silk is fixed with shell fragment (18) in second holding tank (17), the last surface mounting of base (1) has mount pad (3), the last fixed surface of mount pad (3) is connected with motor (30), the output fixedly connected with gear (31) of motor (30), one side meshing of gear (31) is connected with rack (21), and rack (21) screw fixation is on slider (2).

2. A structure for a microfluidic immunofluorescence detection device according to claim 1, wherein: the mounting groove is characterized in that sliding grooves (12) are formed in the inner walls of the two sides of the mounting groove (11), sliding strips (20) are fixedly connected to the outer walls of the two sides of the sliding block (2), and the sliding strips (20) are connected into the sliding grooves (12) in a sliding mode.

3. A structure for a microfluidic immunofluorescence detection device according to claim 1, wherein: a position switch (111) is fixed on the outer wall of one side of the base (1) through screws, and a second blocking piece (24) is fixed on the outer wall of one side of the sliding block (2) through screws at the position corresponding to the position switch (111).

4. A structure for a microfluidic immunofluorescence detection device according to claim 3, wherein: the upper surface of the base (1) is fixedly connected with a connecting block (10), and the connecting block (10) is fixed on the mounting seat (3) through screws.

5. The structure for a microfluidic immunofluorescence detection device according to claim 1, wherein: first through-hole (14) has been seted up on first separation blade (13), first screw hole (15) have been seted up to the position department that corresponds first through-hole (14) on the inner wall of mounting groove (11), second through-hole (19) have been seted up on shell fragment (18), second screw hole (110) have been seted up to the position department that corresponds second through-hole (19) on the inner wall of second holding tank (17), third through-hole (22) have been seted up on rack (21), third screw hole (23) have been seted up to the position department that the upper surface of slider (2) corresponds third through-hole (22), fourth screw hole (32) have been seted up on the outer wall of gear (31).