CN218459138U

CN218459138U - Ultrafiltration device of cell factor

Info

Publication number: CN218459138U
Application number: CN202221899031.1U
Authority: CN
Inventors: 高智星; 胡俊华; 侯方政; 温剑阳
Original assignee: Mobao Xiamen Biotechnology Co ltd
Current assignee: Mobao Xiamen Biotechnology Co ltd
Priority date: 2022-07-21
Filing date: 2022-07-21
Publication date: 2023-02-10
Anticipated expiration: 2032-07-21

Abstract

The utility model provides an ultrafiltration device of cytokine relates to cytokine technical field, including device body and top cap, a plurality of supporting seats of the even fixedly connected with of device body lower surface, device body lower surface is provided with the bleeder valve, the bleeder valve terminal surface is provided with the storage tank, device body upper surface symmetry set up threaded hole, top cap upper surface symmetry is provided with the bolt, the spacing groove has been seted up to device body internal surface symmetry. The utility model discloses in, through the setting of coarse strainer, can filter the impurity of the great volume of doping in the cytokine, avoid impurity to enter into the inside jam that causes of device body, accomplish at the coarse strainer and filter the back, the cooperation setting of first hopper and conical tube can play the effect that slows down the cytokine velocity of flow, avoids causing the interference to the filterable cytokine of ultrafiltration membrane position just depositing, has reduced the required time of sediment filtration, has promoted work efficiency.

Description

Ultrafiltration device of cell factor

Technical Field

The utility model relates to a cytokine technical field especially relates to a cytokine's ultrafiltration device.

Background

The cell factor is a low molecular weight soluble protein which is produced by immunogen, mitogen or other stimulant to induce various cells, has multiple functions of regulating innate immunity and adaptive immunity, hematopoiesis, cell growth, APSC multipotential cells, damaged tissue repair and the like, and needs to be filtered by an ultrafiltration device in the process of preparing the cell factor.

Among the prior art, ultrafiltration device is in the use, the cytokine that preparation was used is liquid, the mobility is stronger, if directly pour cytokine into ultrafiltration device in, the filtered cytokine can be broken away in the ultrafiltration membrane position is just deposiing, wait again that the sediment filters extravagant a lot of time, there is the lower problem of work efficiency, and filter equipment is inconvenient dismantlement usually, remaining cytokine can pile up and cause the jam in the device after long-term the use, still can cause the relatively poor problem of filter effect.

SUMMERY OF THE UTILITY MODEL

The utility model aims at solving prior art, ultrafiltration device is in the use, cytokine for the preparation is liquid, the mobility is stronger, if directly pour cytokine into ultrafiltration device in, just precipitating filterable cytokine can be broken away in the milipore filter position, wait again that precipitation filtration can waste a lot of time, there is the lower problem of work efficiency, and filter equipment is inconvenient dismantlement usually, long-term use back remaining cytokine can pile up and cause the jam in the device, still can cause the relatively poor problem of filter effect, and the ultrafiltration device of a cytokine who provides.

In order to achieve the above purpose, the utility model adopts the following technical scheme: the utility model provides an ultrafiltration device of cell factor, includes device body and top cap, a plurality of supporting seats of the even fixedly connected with of device body lower surface, device body lower surface is provided with the bleeder valve, the bleeder valve terminal surface is provided with the storage tank, device body upper surface symmetry set up threaded hole, top cap upper surface symmetry is provided with the bolt, the spacing groove has been seted up to device body internal surface symmetry, two all be provided with the slider in the spacing groove, two fixedly connected with crosses the filter tank between the slider, cross the filter tank internal surface fixedly connected with coarse filtration jar, coarse filtration jar internal surface is provided with the coarse strainer, coarse filtration jar lower surface is provided with first hopper, first hopper lower surface is provided with the toper pipe, it is provided with the milipore filter to cross the jar internal surface, it is provided with the second hopper to cross the filter tank lower surface, second hopper lower surface is provided with the connecting pipe.

Preferably, the cross sections of the first discharging hopper and the second discharging hopper are both arranged in a conical manner, and the discharging valves are communicated with the storage tank.

Preferably, the outer surfaces of the two sliding blocks are respectively in sliding connection with the inner surfaces of the two limiting grooves, and pull rings are symmetrically and fixedly installed on the inner surface of the coarse filtering tank.

Preferably, the outer surfaces of the two bolts are in threaded connection with the inner surfaces of the two threaded holes respectively, and a discharge hopper is arranged on the upper surface of the top cover.

Preferably, the upper surface of the discharging hopper is hinged with a sealing cover, and the upper surface of the sealing cover is fixedly provided with a handle.

Preferably, the connecting pipe is communicated with the discharge valve, the first discharge hopper is communicated with the conical pipe, and the conical pipe is positioned on the upper surface of the ultrafiltration membrane.

Compared with the prior art, the utility model has the advantages and positive effects that,

1. the utility model discloses in, through the setting of coarse strainer, can filter the impurity of the great volume of doping in the cytokine, avoid impurity to enter into the inside jam that causes of device body, accomplish at the coarse strainer and filter the back, the cooperation setting of first hopper and conical tube can play the effect that slows down the cytokine velocity of flow, avoids causing the interference to the filterable cytokine of ultrafiltration membrane position just depositing, has reduced the required time of sediment filtration, has promoted work efficiency.

2. The utility model discloses in, can carry out the dismouting to the top cap through the setting of bolt, dismantle down the top cap after, the pulling pull ring can take out filtering jar, makes things convenient for the staff to clear up filtering jar and device body inner wall, has solved remaining cytokine and has piled up the problem that probably causes the device to block up, has promoted ultrafiltration device's filter effect.

Drawings

FIG. 1 is a schematic view of the installation structure of the filtration tank of the ultrafiltration device for cytokine of the present invention;

FIG. 2 is a perspective view of the ultrafiltration device of cytokine of the present invention;

FIG. 3 is a schematic view of the top cover mounting structure of the ultrafiltration device for cytokine of the present invention;

fig. 4 is a schematic structural view of a filtration tank of the ultrafiltration device for cytokine of the present invention.

Illustration of the drawings: 1. a device body; 2. a supporting seat; 3. a discharge valve; 4. a material storage tank; 5. a top cover; 6. a bolt; 7. a discharge hopper; 8. a sealing cover; 9. a handle; 10. a limiting groove; 11. a slider; 12. a filtration tank; 13. a coarse filtration tank; 14. a pull ring; 15. coarse filtration; 16. a first discharge hopper; 17. a tapered tube; 18. ultrafiltration membranes; 19. a second discharge hopper; 20. and (4) connecting the pipes.

Detailed Description

In order to make the above objects, features and advantages of the present invention more clearly understood, the present invention will be further described with reference to the accompanying drawings and examples. It should be noted that the embodiments and features of the embodiments of the present application may be combined with each other without conflict.

In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention, however, the present invention may be practiced in other ways than those specifically described herein, and therefore the present invention is not limited to the limitations set forth in the following description of the specific embodiments.

Embodiment 1, as shown in fig. 1-4, the utility model provides an ultrafiltration device of cytokine, including device body 1 and top cap 5, the even fixedly connected with a plurality of supporting seats 2 of device body 1 lower surface, device body 1 lower surface is provided with bleeder valve 3, bleeder valve 3 terminal surface is provided with storage tank 4, fixedly connected with filter tank 12 between two sliders 11, filter tank 12 internal surface fixedly connected with coarse filtration jar 13, coarse filtration jar 13 internal surface is provided with coarse strainer 15, coarse filtration jar 13 lower surface is provided with first play hopper 16, first play hopper 16 lower surface is provided with conical tube 17, filter tank 12 internal surface is provided with milipore filter 18, filter tank 12 lower surface is provided with second play hopper 19, second play hopper 19 lower surface is provided with connecting pipe 20, first play hopper 16 all is the toper setting with second play hopper 19 cross-section, bleeder valve 3 is the intercommunication setting with storage tank 4, top cap 5 upper surface is provided with hopper 7, discharge hopper 7 upper surface hinged joint has sealed lid 8, sealed lid 8 upper surface fixed mounting has handle 9, connecting pipe 20 is the intercommunication setting with bleeder valve 3, first play hopper 16 is the toper pipe 17 and is located the milipore filter 17.

The effect that its whole embodiment 1 reached does, supporting seat 2 sets up to device body 1 and provides stable support, the cell factor that sealed lid 8 will need to carry out the processing is opened to pulling handle 9 and is poured into through blowing fill 7, cover and seal lid 8 back and provide sealed protection for device body 1 is inside, cell factor can firstly get into coarse strainer 15 position and filter the great impurity in the cell factor, later cell factor flows into in conical tube 17 through first blowing fill 16, conical tube 17 and the cooperation of first blowing fill 16 have played the effect that slows down the cell factor velocity of flow, avoid disturbing ultrafiltration membrane 18 position and just depositing filterable cell factor, cell factor passes through ultrafiltration membrane 18 and accomplishes the filtration back, flow into second blowing fill 19, pour into bleeder valve 3 position through connecting pipe 20, it can store cell factor in jar 4 to open bleeder valve 3.

Embodiment 2, as shown in fig. 1 to 4, threaded holes are symmetrically formed in the upper surface of the device body 1, bolts 6 are symmetrically arranged on the upper surface of the top cover 5, the outer surfaces of the two bolts 6 are respectively in threaded connection with the inner surfaces of the two threaded holes, limiting grooves 10 are symmetrically formed in the inner surface of the device body 1, sliders 11 are arranged in the two limiting grooves 10, the outer surfaces of the two sliders 11 are respectively in sliding connection with the inner surfaces of the two limiting grooves 10, and pull rings 14 are symmetrically and fixedly installed on the inner surface of the coarse filtration tank 13.

The effect that its whole embodiment 2 reached does, can accomplish the dismouting to top cap 5 through setting up of bolt 6, and the pulling pull ring 14 can directly take out and filter jar 12, makes things convenient for the staff to wash filter jar 12 and device body 1 inner wall, and spacing groove 10 sets up to filter jar 12 with the cooperation of slider 11 and has played limiting displacement, uses connecting pipe 20's rigidity and bleeder valve 3 cooperation.

The working principle is as follows: cell factor that needs to handle pours into through blowing fill 7, cover and provide sealed guard action for device body 1 behind the sealed lid 8, cell factor pours into the back and can filter the impurity in the cell factor through coarse filtration jar 13, play the effect that slows down the cell factor velocity of flow through first hopper 16 and the cooperation of conical duct 17 after the coarse filtration is accomplished, milipore filter 18 accomplishes to cell factor and stores cell factor in storage tank 4 through bleeder valve 3 after filtering, can accomplish the dismantlement to top cap 5 through setting up of bolt 6, pull ring 14 after pulling top cap 5, make things convenient for the staff to clear up filter tank 12 and device body 1 inner wall.

The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention in other forms, and any person skilled in the art may use the above-mentioned technical contents to change or modify the equivalent embodiment into equivalent changes and apply to other fields, but any simple modification, equivalent change and modification made to the above embodiments according to the technical matters of the present invention will still fall within the protection scope of the technical solution of the present invention.

Claims

1. An ultrafiltration device of cytokines, comprising a device body (1) and a top cover (5), characterized in that: the device body (1) a plurality of supporting seats (2) of even fixedly connected with of lower surface, device body (1) lower surface is provided with bleeder valve (3), bleeder valve (3) terminal surface is provided with storage tank (4), device body (1) upper surface symmetry set up threaded hole, top cap (5) upper surface symmetry is provided with bolt (6), spacing groove (10), two have been seted up to device body (1) inner surface symmetry all be provided with slider (11), two in spacing groove (10) fixedly connected with crosses filter tank (12) between slider (11), it has coarse filtration jar (13) to cross filter tank (12) internal surface fixedly connected with, coarse filtration jar (13) internal surface is provided with coarse strainer (15), coarse filtration jar (13) lower surface is provided with first play hopper (16), first play hopper (16) lower surface is provided with toper pipe (17), it is provided with milipore filter tank (18) internal surface to cross filter tank (12), it is provided with second play hopper (19) to cross filter tank (12) lower surface, second play hopper (19) lower surface is provided with connecting pipe (20).

2. The cytokine ultrafiltration device of claim 1, wherein: the sections of the first discharging hopper (16) and the second discharging hopper (19) are both arranged in a conical manner, and the discharging valve (3) is communicated with the storage tank (4).

3. The ultrafiltration device of cytokines according to claim 1, characterized in that: the outer surfaces of the two sliding blocks (11) are respectively in sliding connection with the inner surfaces of the two limiting grooves (10), and pull rings (14) are symmetrically and fixedly installed on the inner surface of the coarse filtration tank (13).

4. The cytokine ultrafiltration device of claim 1, wherein: the outer surfaces of the two bolts (6) are respectively in threaded connection with the inner surfaces of the two threaded holes, and a discharge hopper (7) is arranged on the upper surface of the top cover (5).

5. The cytokine ultrafiltration device of claim 4, wherein: the upper surface hinge connection of blowing fill (7) has sealed lid (8), fixed surface installs handle (9) on sealed lid (8).

6. The cytokine ultrafiltration device of claim 1, wherein: connecting pipe (20) are the intercommunication setting with bleeder valve (3), first play hopper (16) are the intercommunication setting with conical duct (17), conical duct (17) are located milipore filter (18) upper surface.