CN218393156U

CN218393156U - Reactor (mixing) shaft for bio-medical treatment

Info

Publication number: CN218393156U
Application number: CN202222554237.7U
Authority: CN
Inventors: 张�杰
Original assignee: Yingmaiji Technology Nantong Co ltd
Current assignee: Yingmaiji Technology Nantong Co ltd
Priority date: 2022-09-27
Filing date: 2022-09-27
Publication date: 2023-01-31
Anticipated expiration: 2032-09-27

Abstract

The utility model discloses a reactor (mixing) shaft for bio-medical treatment belongs to bioreactor technical field, and it includes the anticorrosive (mixing) shaft body of carbon steel, the outside of the anticorrosive (mixing) shaft body of carbon steel is provided with two spacing support sleeve. This reactor (mixing) shaft for bio-medical treatment, through setting up flexible stirring vane, the erection bracing piece, the waterproof scraper blade of rubber, the rubber cardboard, strong magnetism attracts iron plate and flexible fixture block, make this device when using, liquid upwards 45 degrees directions flows when guaranteeing the stirring through the tilt state of flexible stirring vane, cell and microcarrier can suspend along with the flow of liquid naturally, can reduce the probability of damaging the cell simultaneously, the growth state and the quantity of cell have been ensured, and can scrape the material at the inner wall of flexible stirring vane's length value within range to the reactor through the waterproof scraper blade of rubber, and with the detachable mode of flexible stirring vane, the convenience of tearing open of the waterproof scraper blade of rubber and actual use effect have also been increased.

Description

Reactor (mixing) shaft for bio-medical treatment

Technical Field

The utility model belongs to the technical field of bioreactor, specifically be a reactor (mixing) shaft for bio-medical treatment.

Background

With the development of biomedical technology, the application of bioreactors in the biopharmaceutical industry is becoming more and more extensive, especially in the application of large-scale cell culture, the bioreactor refers to a system (or place) that effectively utilizes the functions of a bioreactor, and includes not only a traditional fermentation tank and an enzyme reactor, but also an immobilized enzyme or cell reactor after the immobilization technology, a reactor for culturing animal and plant cells, a photosynthetic bioreactor, and the like, and the bioreactor is divided into a stretching or direct dynamic compression bioreactor, a rotating arm bioreactor, a stirring bioreactor, a hydraulic bioreactor, a perfusion bioreactor, a rolling dynamic loading bioreactor, and the like.

Bioreactor need use the (mixing) shaft to stir cell and microcarrier in the reactor when using, but stirring bearing's structure is very simple, be equipped with a plurality of flexible stirring vane pieces on each (mixing) shaft, flexible stirring vane piece is perpendicular angle with the plane of stirring rake, this area that just causes stirring in-process blade and cell direct contact is too big, the injury probability of cell has been increased, thereby the growth state and the quantity of cell have been influenced, be not convenient for strike off the cell of reactor inner wall adhesion and microcarrier simultaneously, and rubber waterproof scraper blade also be convenient for when appearing damaging change, thereby influence follow-up use.

Disclosure of Invention

In order to overcome the defects, the utility model provides a reactor (mixing) shaft for bio-medical treatment has solved stirring in-process blade and cell direct contact's area too big, has increased the injury probability of cell to influence the growth state and the quantity of cell, be not convenient for strike off the cell machine microcarrier of reactor inner wall adhesion simultaneously, and rubber waterproof scraper blade also be convenient for change when appearing damaging, thereby influence the problem of follow-up use.

In order to achieve the above object, the utility model provides a following technical scheme: the utility model provides a reactor (mixing) shaft for bio-medical treatment, includes the anticorrosive (mixing) shaft body of carbon steel, the outside of the anticorrosive (mixing) shaft body of carbon steel is provided with two spacing support sleeves, the flexible stirring vane of a plurality of spacing support sleeve's outside fixedly connected with, the flexible stirring vane is kept away from one side of spacing support sleeve and has been seted up the rubber constant head tank.

The rubber positioning groove is internally provided with a rubber clamping plate, two strong magnetic attraction iron blocks are fixedly connected to the side face of the rubber clamping plate, two same flexible clamping blocks are lapped on the inner side of each strong magnetic attraction iron block, an installation positioning block is fixedly connected to one side of each strong magnetic attraction iron block and is far away from each flexible clamping block, and a rubber waterproof scraper is fixedly connected to the side face of each installation positioning block.

As a further aspect of the present invention: the rubber clamping plate is arranged in a V shape.

As a further aspect of the present invention: the rubber cardboard sets up in flexible stirring blade, the waterproof scraper blade of rubber sets up to "L" shape.

As a further aspect of the present invention: the flexible stirring blade is set to be in an inclined shape, and the flexible stirring blade and the plane of the limiting support sleeve are arranged at 45 degrees.

As a further aspect of the present invention: the strong magnetic attraction iron block is positioned in the rubber positioning groove, and the flexible stirring blades are positioned outside the limiting support sleeve and are in a circular array structure.

As a further aspect of the present invention: the installation positioning blocks and the rubber positioning grooves are arranged in a one-to-one correspondence mode.

As a further aspect of the present invention: the flexible clamping block is arranged in an arrow shape and is positioned in the rubber positioning groove.

As a further aspect of the present invention: the waterproof rubber scraper is arranged at 45 degrees to the plane of the limiting support sleeve, and the waterproof rubber scraper is the same as the flexible stirring blade in inclination.

Compared with the prior art, the beneficial effects of the utility model reside in that:

1. this reactor (mixing) shaft for bio-medical treatment, through setting up flexible stirring vane, the erection locating piece, the waterproof scraper blade of rubber, the rubber cardboard, strong magnetism attracts iron piece and flexible fixture block, press the erection locating piece, thereby drive flexible fixture block and remove, make flexible fixture block and strong magnetism attract iron piece contact, continue to press flexible fixture block, and can pass strong magnetism and inhale the iron piece card with flexible fixture block through the elasticity of rubber cardboard self and go into in the rubber cardboard, and strong magnetism attracts iron piece together through the magnetic force of self, so as to install the waterproof scraper blade of rubber, make this device when using, liquid upwards 45 degrees directions flow when guaranteeing the stirring through the slope state of flexible stirring vane, cell and microcarrier can suspend along with the flow of liquid naturally, can reduce the probability of damaging the cell simultaneously, the growth state and the quantity of cell have been ensured, and can scrape the material to the inner wall of reactor in flexible stirring vane's length value range through the waterproof scraper blade of rubber, and with the detachable mode of flexible stirring vane, the convenience of tearing open and the in-service use effect of rubber waterproof scraper blade have also been increased.

2. This reactor (mixing) shaft for bio-medical treatment, through setting up the rubber cardboard, and the rubber cardboard is the rubber material, can adjust the angle of rubber cardboard to inhale the magnetic force through strong magnetism magnet iron piece self and make two strong magnetism magnet iron pieces attract each other to be close to, can carry on spacingly to the position of flexible fixture block, guaranteed the stability of flexible fixture block when using, avoid appearing rocking and the condition that drops.

3. This reactor (mixing) shaft for bio-medical treatment, through setting up the waterproof scraper of rubber, and the waterproof scraper of rubber is the slope setting, make the waterproof scraper of rubber can reduce the area of contact between cell and the waterproof scraper of rubber when striking off the reactor inner wall, the waterproof scraper of rubber is the rubber material simultaneously, and the waterproof scraper of rubber surface parcel has the waterproof layer, can cushion the position of contact between waterproof scraper of rubber and cell and the microcarrier, thereby reduce the damage that cell and microcarrier produced, the waterproof scraper of rubber can reduce the area of contact between cell and the waterproof scraper of rubber when striking off the reactor inner wall simultaneously, thereby avoid piling up of reactor inner wall cell.

Drawings

Fig. 1 is a schematic three-dimensional structure of the present invention;

FIG. 2 is a schematic three-dimensional structure view of the flexible stirring blade of the present invention;

FIG. 3 is a schematic structural view of a section of the flexible stirring blade of the present invention;

fig. 4 is a schematic three-dimensional structure diagram of the flexible fixture block of the present invention;

in the figure: 1 anticorrosive (mixing) shaft body of carbon steel, 2 spacing support sleeve, 3 flexible stirring vane, 4 erection bracing pieces, 5 waterproof scraper blades of rubber, 6 rubber constant head tanks, 7 rubber cardboard, 8 strong magnetism inhale iron plate, 9 flexible fixture blocks.

Detailed Description

The present invention will be described in detail with reference to the accompanying drawings and specific embodiments.

In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, are not to be construed as limiting the present invention. Furthermore, the terms "first," "second," and the like are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

As shown in fig. 1-4, the utility model provides a technical solution: a reactor stirring shaft for biomedical treatment comprises a carbon steel anticorrosion stirring shaft body 1, two limiting support sleeves 2 are arranged on the outer side of the carbon steel anticorrosion stirring shaft body 1, a plurality of flexible stirring blades 3 are fixedly connected to the outer sides of the limiting support sleeves 2, and the flexible stirring blades 3 can be supported and driven to rotate by arranging the limiting support sleeves 2, so that the stability of the flexible stirring blades 3 in movement is ensured;

the outside that flexible stirring blade 3 is located spacing support sleeve 2 is circular array structure, flexible stirring blade 3 sets up to the slope shape, and flexible stirring blade 3 is 45 degrees settings with the plane of spacing support sleeve 2, through setting up flexible stirring blade 3, and the slope state through flexible stirring blade 3 is with the upwards 45 degrees orientations of liquid flow when guaranteeing the stirring, cell and microcarrier can suspend along with the flow of liquid naturally, reduce the probability of damaging the cell simultaneously, and flexible stirring blade 3 is polymer ceramic, polymer ceramic is one kind and uses the polymer as the binder, pottery is the filler, the compound novel ceramic polymer material that forms, wear-resisting anticorrosive has, temperature resistance and feature of environmental protection, and flexible stirring blade 3's outside fixedly connected with flexible inoxidizing coating, can protect flexible stirring blade 3, simultaneously can cushion the contact between flexible stirring blade 3 and cell and the microcarrier, thereby reduce the probability that cell and microcarrier damaged, stirring efficiency has been improved.

Flexible stirring vane 3 keeps away from one side of spacing support sleeve 2 and has seted up rubber constant head tank 6, be provided with rubber cardboard 7 in the rubber constant head tank 6, rubber cardboard 7 sets up to "V" shape, rubber cardboard 7 sets up in flexible stirring vane 3, through setting up rubber cardboard 7, and rubber cardboard 7 is the rubber material, can adjust the angle of rubber cardboard 7, and inhale the magnetic force through strong magnetism 8 self and make two strong magnetism 8 attract each other to be close to, thereby it is fixed to carry out the joint to flexible fixture block 9, the stability of flexible fixture block 9 when using has been guaranteed, avoid appearing rocking and the condition that drops.

Two strong magnetic iron blocks 8 are fixedly connected to the side face of the rubber clamping plate 7, the strong magnetic iron blocks 8 are located in the rubber positioning groove 6, the inner sides of the two strong magnetic iron blocks 8 are lapped with the same flexible fixture block 9, the positions of the flexible fixture blocks 9 can be limited by the strong magnetic iron blocks 8 through the arrangement of the strong magnetic iron blocks 8 and the flexible fixture blocks 9, the two sides of each flexible fixture block 9 are arc-shaped, the strong magnetic iron blocks 8 can be tightly attached to the arc-shaped positions of the flexible fixture blocks 9 through the magnetic force of the strong magnetic iron blocks 8, and therefore the positions of the flexible fixture blocks 9 are fixed;

flexible fixture block 9 sets up to the arrow point shape, flexible fixture block 9 is located

rubber positioning groove

6, 8 one side fixedly connected with erection locating piece 4 of strong magnetism magnet that flexible fixture block 9 kept away from, through setting up flexible fixture block 9, make flexible fixture block 9 can cushion the outside of flexible fixture block 9 when the strong magnetism magnet 8 is inhaled to the card, avoid flexible fixture block 9 to inhale the condition that iron 8 internal collision leads to the strong magnetism to inhale wearing and tearing and damage in iron 8 with the strong magnetism when the strong magnetism is inhaled to the card in iron 8.

The waterproof scraper blade 5 of side fixedly connected with rubber of erection locating piece 4, the waterproof scraper blade 5 of rubber sets up to "L" shape, the waterproof scraper blade 5 of rubber is 45 degrees settings with the plane of spacing support sleeve 2, and the waterproof scraper blade 5 of rubber is the same with flexible stirring blade 3's gradient, through setting up the waterproof scraper blade 5 of rubber, and the waterproof scraper blade 5 of rubber is the slope setting, make the waterproof scraper blade 5 of rubber can reduce the area of contact between cell and the waterproof scraper blade 5 of rubber when striking off the reactor inner wall, thereby avoid piling up of reactor inner wall cell, the waterproof scraper blade 5 of rubber is the rubber material simultaneously, and the waterproof scraper blade 5 surface parcel of waterproof scraper blade of rubber has the waterproof layer, can cushion the position of contact between waterproof scraper blade 5 of rubber and cell and the microcarrier, thereby reduce the probability of cell and microcarrier damage, be the one-to-one setting between erection locating piece 4 and the rubber constant head tank 6.

The utility model discloses a theory of operation does:

when the flexible stirring blade is used, the mounting and positioning blocks 4 correspond to the rubber positioning grooves 6 on the surfaces of the flexible stirring blades 3 one by one, and then the mounting and positioning blocks 4 are pressed, so that the mounting and positioning blocks 4 are moved into the rubber positioning grooves 6, the mounting and positioning blocks 4 can drive the flexible clamping blocks 9 to move when moving, and the flexible clamping blocks 9 are in contact with the strong magnetic iron attracting blocks 8;

then, the flexible fixture block 9 is continuously pressed, the flexible fixture block 9 is clamped between the two strong magnetic attraction iron blocks 8 through the elasticity of the flexible fixture block 9, the two strong magnetic attraction iron blocks 8 move towards two sides, and when the strong magnetic attraction iron blocks 8 move through the elasticity of the rubber clamping plate 7, the angle of the rubber clamping plate 7 can be adjusted, so that the flexible fixture block 9 moves into the rubber clamping plate 7, meanwhile, the two strong magnetic attraction iron blocks 8 can be attracted to each other and approach each other through the magnetic force of the strong magnetic attraction iron blocks 8, and the two strong magnetic attraction iron blocks 8 are adsorbed at the arc-shaped part on the outer side of the flexible fixture block 9;

secondly inhale iron plate 8 through two strong magnetism and can carry out spacing fixed to the position of flexible fixture block 9, thereby carry on spacingly to the position of erection locating piece 4, and then can install rubber waterproof scraper blade 5 in flexible stirring vane 3, when carbon steel anticorrosive (mixing) shaft body 1 drives spacing support sleeve 2 and rotates, can drive a plurality of flexible stirring vane 3 and rotate simultaneously, thereby drive a plurality of rubber waterproof scraper blades 5 and rotate, so that stir the inner wall to the reactor to the cell in the reactor and strike off the work.

In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood as a specific case by those skilled in the art.

In the description of the present specification, reference to the description of "one embodiment," "some embodiments," "an example," "a specific example," or "some examples" or the like means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It should be understood by those skilled in the art that the above embodiments do not limit the present invention in any way, and all technical solutions obtained by adopting equivalent replacement or equivalent transformation fall within the protection scope of the present invention.

Claims

1. The utility model provides a reactor (mixing) shaft for bio-medical treatment, includes anticorrosive (mixing) shaft body of carbon steel (1), its characterized in that: two limiting support sleeves (2) are arranged on the outer side of the carbon steel anticorrosion stirring shaft body (1), a plurality of flexible stirring blades (3) are fixedly connected to the outer sides of the limiting support sleeves (2), and rubber positioning grooves (6) are formed in one sides, away from the limiting support sleeves (2), of the flexible stirring blades (3);

be provided with rubber cardboard (7) in rubber constant head tank (6), iron piece (8) are inhaled to two strong magnetism of the side fixedly connected with of rubber cardboard (7), two the inboard overlap joint of iron piece (8) is inhaled to the strong magnetism has same flexible fixture block (9), iron piece (8) one side fixedly connected with erection locating piece (4) are inhaled to strong magnetism that flexible fixture block (9) were kept away from, the waterproof scraper blade of side fixedly connected with rubber (5) of erection locating piece (4).

2. The stirring shaft of a biomedical reactor as claimed in claim 1, wherein: the rubber clamping plate (7) is V-shaped.

3. The stirring shaft of a biomedical reactor as claimed in claim 1, wherein: the rubber clamping plate (7) is arranged in the flexible stirring blade (3), and the rubber waterproof scraper (5) is arranged in an L shape.

4. The stirring shaft of a biomedical reactor as claimed in claim 1, wherein: the flexible stirring blade (3) is arranged in an inclined shape, and the flexible stirring blade (3) and the plane of the limiting support sleeve (2) are arranged at 45 degrees.

5. The stirring shaft of the biomedical reactor according to claim 1, wherein: the strong magnetic attraction iron block (8) is positioned in the rubber positioning groove (6), and the flexible stirring blade (3) is positioned on the outer side of the limiting support sleeve (2) and is of a circular array structure.

6. The stirring shaft of a biomedical reactor as claimed in claim 1, wherein: the installation positioning blocks (4) and the rubber positioning grooves (6) are arranged in a one-to-one correspondence mode.

7. The stirring shaft of a biomedical reactor as claimed in claim 1, wherein: the flexible clamping block (9) is in an arrow shape, and the flexible clamping block (9) is located in the rubber positioning groove (6).

8. The stirring shaft of a biomedical reactor as claimed in claim 1, wherein: the rubber waterproof scraper (5) and the plane of the limiting support sleeve (2) are arranged at 45 degrees, and the rubber waterproof scraper (5) and the flexible stirring blade (3) are the same in gradient.