CN218382843U - Portable fecal occult blood detection device - Google Patents
Portable fecal occult blood detection device Download PDFInfo
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- CN218382843U CN218382843U CN202222045262.2U CN202222045262U CN218382843U CN 218382843 U CN218382843 U CN 218382843U CN 202222045262 U CN202222045262 U CN 202222045262U CN 218382843 U CN218382843 U CN 218382843U
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Abstract
The utility model discloses a portable fecal occult blood detection device, which comprises a micro-flow regulation controller, an upper cavity and a lower cavity; the upper cavity is internally pre-filled with detection liquid and is matched with an acquisition component; a liquid through hole is formed in the joint of the micro-flow regulation controller and the upper cavity, and a liquid conveying hose communicated with the liquid through hole is arranged at the joint of the micro-flow regulation controller and the lower cavity; the lower cavity body is internally provided with a plurality of colloidal gold test strips with clamping grooves, and rectangular small holes are formed in the bottoms of the clamping grooves. The utility model discloses the device gathers sample collection and detects and can carry out the multiple detection in an organic whole, can realize the accurate quantitative determination of sample, reduces the difference that the sample inequality caused, avoids sample hemoglobin concentration too high to appear false negative's problem, and is more accurate to the detection of asphalt stool or bright blood stool simultaneously.
Description
Technical Field
The utility model relates to a medical treatment detects technical field, concretely relates to portable just occult blood detection device.
Background
Stool detection is one of effective methods for evaluating whether bleeding exists in the digestive system, and provides certain diagnostic basis in the aspects of evaluation of intestinal health conditions, clinical diagnosis of intestinal inflammatory diseases and the like. The fecal occult blood test is an auxiliary diagnosis method for detecting the bleeding of the digestive tract, and is mainly used for the small bleeding of the digestive tract which can not be judged by naked eyes, and the fecal occult blood has wide clinical diagnosis value in the diagnosis of the bleeding of the digestive tract.
Fecal occult blood test (fecal occult blood test) is an effective routine examination for diagnosing and monitoring digestive tract hemorrhagic diseases, and is also one of the important means for discovering digestive tract tumors. The most commonly used methods at present are chemical methods (including o-biphenylamine method, occult blood powder method, guaiac method) and immunological methods (colloidal gold-labeled sandwich immunization). The traditional chemical method has low cost, but has more false positives, low sensitivity and carcinogenicity to operators; the cost of the new immune colloidal gold method is slightly higher, but the immune colloidal gold method is more and more widely used because of good specificity, no dietary restriction, rapidness, convenience, accuracy and convenience for clinical application. The detection method of the fecal occult blood test is multiple, compared with the traditional chemical method, the immunoassay method has the advantages of simple and convenient operation, quick result display, easy observation and no need of reagent preparation, avoids the harm of toxicity of certain chemical reagents to operators, and brings convenience to daily work.
The immune colloidal gold method combines the monoclonal technology with the colloidal gold technology, and detects fecal occult blood by utilizing the characteristic that the monoclonal antibody of anti-human hemoglobin or anti-human erythrocyte matrix has high specificity with human hemoglobin or human erythrocyte. The preparation of monoclonal antibody of human hemoglobin can apply various immunity techniques to specifically detect fecal occult blood. The method has much higher sensitivity than the chemical method, can detect 0.05 mu g/ml of hemoglobin, namely can detect trace hemoglobin in excrement, and is very important for early diagnosis of gastrointestinal hemorrhagic diseases and has no cross reaction with various meats, vegetables and medicines.
However, the colloidal gold method also has a disadvantage that when the hemoglobin content in the sample is too high or too low, false negative can occur because: when the hemoglobin content in the sample is too low, too few antibody-antigen-antibody-colloidal gold complexes are formed, and no macroscopic color reaction appears on a detection line; when the hemoglobin concentration in the sample is too high, the antigen is excessive to generate a band phenomenon, thereby causing the occurrence of false negative. When a patient has a large hemorrhage in the digestive tract, the hemoglobin concentration in the excrement is too high and becomes asphalt-like stool, and false negative is easy to appear due to the phenomenon of posterior banding in the immune colloidal gold detection.
SUMMERY OF THE UTILITY MODEL
In view of this, the utility model discloses it is expected to provide a portable just occult blood detection device collects sample collection and detects and can carry out a lot of in an organic whole and detect, can realize the accurate quantitative determination of sample, reduces the uneven difference that causes of sample, avoids sample hemoglobin concentration too high to appear the problem of false negative, and is more accurate to the detection of asphalt stool or fresh blood stool simultaneously.
In order to achieve the above purpose, the technical scheme of the utility model is realized like this:
the utility model provides a portable fecal occult blood detection device, which comprises a micro-flow regulation controller, an upper cavity and a lower cavity; the upper cavity is internally pre-filled with detection liquid and is matched with an acquisition component; a liquid through hole is formed in the joint of the micro-flow regulation controller and the upper cavity, and a liquid conveying hose communicated with the liquid through hole is arranged at the joint of the micro-flow regulation controller and the lower cavity; the lower cavity body is internally provided with a plurality of colloidal gold test strips with clamping grooves, and rectangular small holes are formed in the bottoms of the clamping grooves.
Further, gather the part including with integrative sampling stick, the sampling head of screw block, twist with the screw of last cavity bottleneck through screw block and open and shut.
Preferably, the rod body of the sampling rod is telescopic, and the sampling head is detachable.
Preferably, the sampling head is a smooth geometric body or a geometric body with dense well-shaped concave strips.
More preferably, the geometric body may be any one of an ellipsoid, a cuboid and a cube.
Preferably, the colloidal gold test strips are different in height and are staggered up and down, and the distance of at least half the length of the test strip is reserved between the two test strips.
Furthermore, a water permeable film is arranged at the top end of the liquid conveying hose, the aperture is not less than 0.8 mu m, and the water permeable film is a polypropylene filter membrane.
Furthermore, the device also comprises a standby detection liquid, and a drying sheet is also arranged at the joint of the micro-flow regulation controller and the lower cavity.
Preferably, the liquid conveying hose, the upper cavity and the lower cavity are made of transparent PET plastic, and the upper cavity and the lower cavity are provided with digital scale marks.
Further, the detection liquid is distilled water.
The utility model discloses beneficial effect as follows: 1) The device can repeatedly add the detection liquid to dilute the sample, and carry out multiple detections, and has simple and convenient overall operation and high practicability; 2) The utility model can realize accurate and quantitative detection of samples, and is convenient to carry; 3) The sampling head arranged in the device can increase the contact area with the sample, reduce the difference caused by uneven sampling and avoid the problem of false negative caused by overhigh concentration of hemoglobin in the sample; 4) The utility model discloses the device is more accurate to the detection of asphalt stool or fresh blood stool.
Drawings
FIG. 1 is a schematic structural view of a portable fecal occult blood detection device according to an embodiment of the present invention;
FIG. 2 is a perspective view of a micro-flow regulating controller of the portable fecal occult blood detecting device according to the embodiment of the present invention;
FIG. 3 is a schematic structural view of a collecting member of a first embodiment of the portable fecal occult blood detecting device of the present invention;
FIG. 4 is a schematic structural view of a second embodiment of a collecting member of the portable fecal occult blood detecting device of the present invention;
FIG. 5 is a schematic view of the structure of the collecting member of the third embodiment of the portable fecal occult blood detecting device of the present invention;
FIG. 6 is a schematic view of a fourth embodiment of the collecting member of the portable fecal occult blood detecting device of the present invention;
wherein: 1 is a micro-flow adjusting controller, 2 is an upper cavity, 3 is a lower cavity, 4 is a detection liquid, 5 is a screw cap, 6 is a sampling rod, 7 is a sampling head, 8 is a screw thread at the bottleneck of the upper cavity, 9 is a liquid through hole, 10 is a liquid conveying hose, 11 is a clamping groove, 12 is a colloidal gold test strip, 13 is a drying sheet, 14 is a water permeable film, 15 is a digital scale mark, and 16 is a telescopic node.
Detailed Description
In order to understand the features and technical contents of the present invention in more detail, the following description is given in conjunction with the accompanying drawings, which are only used for reference and not for limiting the present invention.
Fig. 1 is a schematic structural view of a portable fecal occult blood detection device according to an embodiment of the present invention, and fig. 2 is a perspective structural view of a micro-flow regulating controller in the portable fecal occult blood detection device according to an embodiment of the present invention, as shown in fig. 1 and fig. 2, the portable fecal occult blood detection device includes a micro-flow regulating controller 1, an upper cavity 2, and a lower cavity 3; the upper cavity is internally pre-filled with detection liquid 4 and is matched with a collecting component, the collecting component comprises a sampling rod 6 and a sampling head, the sampling rod and the sampling head are integrated with a screw cap, the sampling rod is screwed with a screw thread 8 at the bottleneck of the upper cavity through the screw cap 5 to be opened and closed, the rod body of the sampling rod can stretch, and the sampling head 7 can be detached; a liquid through hole 9 is formed in the joint of the micro-flow regulation controller 1 and the upper cavity 2, and a liquid conveying hose 10 communicated with the liquid through hole 9 is arranged at the joint of the micro-flow regulation controller 1 and the lower cavity 3; a plurality of colloidal gold test strips 12 with clamping grooves 11 are arranged in the lower cavity 3, and rectangular small holes are formed in the bottoms of the clamping grooves.
The sampling rod 6 can be elongated in the sampling process to sample, the sampling rod is placed in the upper cavity 2 and mixed with the detection liquid 4 after sampling, and the sampling head 7 touches the bottom of the upper cavity 2 and is shortened to the length matched with the upper cavity under the action of force.
The bottom of the clamping groove is provided with a small rectangular hole, so that the colloidal gold test strip can be clamped in and contacted with a mixed solution flowing down from the upper cavity in the detection process conveniently.
Preferably, the colloidal gold test strips 12 are different in height and are attached in a vertically staggered manner, the distance between the two test strips is at least half the length of the test strip, and the colloidal gold test strips with different heights are attached to the lower cavity, so that the detection can be carried out for a plurality of times such as two times, three times and the like, the operation is simple and convenient, and the practicability is high.
Further, the top end of the liquid conveying hose 10 is provided with a water permeable film 14, the aperture is not less than 0.8 μm, and the water permeable film 14 is a polypropylene filter membrane, so that the passing of the detected liquid is not influenced, and the filtering of coarse impurities can be realized.
Furthermore, a dry sheet 13 is further arranged at the joint of the micro-flow regulation controller 1 and the lower cavity 3, specifically, a sheet-shaped drying agent is pasted on the side wall, and the double protection effect on the humidity-sensitive colloidal gold test strip is achieved.
Preferably, the liquid conveying hose 10 is made of TPE, and compared with the conventional PVC material, the liquid conveying hose is free of plasticizer, safe and environment-friendly.
Preferably, go up the cavity 2 with cavity 3 all uses transparent PET material plastics to make down, go up cavity 2 with cavity 3 all is equipped with digital scale mark 15 down, is convenient for like this observe the sample mixed condition of cavity to and the glass short contact condition of bottom glass of lower cavity mixed solution and test paper strip.
Furthermore, the device also comprises a standby detection liquid, the detection liquid plays a role in destroying red blood cells so as to release hemoglobin, and the sample with false negative can be diluted and then detected for multiple times.
Further, the detection solution is distilled water.
FIG. 3 is a schematic structural view of a collecting member of a first embodiment of the portable fecal occult blood detecting device of the present invention; FIG. 4 is a schematic structural view of a second embodiment of a collecting member of the portable fecal occult blood detecting device of the present invention; FIG. 5 is a schematic view of the structure of the collecting member of the third embodiment of the portable fecal occult blood detecting device of the present invention; FIG. 6 is a schematic view of a fourth embodiment of the collecting member of the portable fecal occult blood detecting device of the present invention; combine fig. 3 to fig. 6 to show, the utility model discloses collection part in the device includes sampling stick 6, sampling head 7 integrative with the screw nut cap, the sampling stick shaft is scalable, and the sampling head can be dismantled, sampling head 7 has the geometry of intensive well check form concave strip for smooth geometry or body, the geometry can be any one in ellipsoid, cuboid, the square.
The utility model discloses the geometry that smooth geometry or body have intensive well check form concave strip can be set to the sampling head among the device, and geometry sampling head contact sample area is big, can avoid appearing the inhomogeneous and difference that causes of sample.
The sampling rod with the geometric body sampling head is used for collecting samples, the geometric body sampling head can be detached and replaced, the smooth-surface geometric body sampling head can be selected by observing the characteristics of the samples, such as asphalt excrement or fresh blood through naked eyes, and the phenomenon that when the concentration of hemoglobin in the samples is too high, the antigens are excessive to generate a posterior band phenomenon, so that false negative can be caused; in other cases, the geometric body sampling head with the dense well-shaped grid on the surface can be used for quantitative collection of samples, and the geometric body sampling head can be detached and replaced according to the properties of the samples.
The utility model relates to a portable just occult blood detection device's operation process as follows:
the sampling part in the upper cavity is screwed and taken down, the rod body of the sampling rod can be elongated in the sampling process, the telescopic joint 16 is arranged, the cleanness and the convenience in the sampling process are enhanced, different sampling heads are used according to the properties of a sample, the sampling rod is placed in the upper cavity after sampling is finished, a cap is screwed with the bottle neck of the upper cavity in a threaded rotating manner, the collected sample is mixed with detection liquid in the upper cavity, the sampling head touches the bottom of the upper cavity and is shortened to the length matched with the upper cavity under the action of force, the sample and the detection liquid are mixed to form mixed liquid to be detected, a micro-flow regulation controller is connected below the upper cavity, a liquid through hole is formed between the sample and the detection liquid, and a liquid conveying hose communicated with the liquid through hole is arranged at the joint of the micro-flow regulation controller and the lower cavity; wait to detect liquid and pass through the through-flow hole, the micro-flow regulation controller opens and adjusts the velocity of flow, cavity under the liquid delivery hose gets into, wait to detect the liquid volume of getting into cavity down and reach the demand after, the rotation micro-flow regulation controller makes it be in the closed condition, realize going up the quantitative accurate control that the liquid was waited to detect to the cavity, wait to detect the liquid afterwards and run the board through the fine siphon effect of colloidal gold test paper strip glass and appear the typewriter ribbon, whether single line appears according to the test paper strip or two lines judge masculinely and negatively, it is negative to appear the single line, it is then masculine to appear two lines.
When the stool character is asphalt stool or fresh bloody stool and the detection result is negative, the stool is diluted and then detected, a certain proportion of the detection liquid for standby is added into the upper cavity to dilute the existing mixed liquid, and the scale mark outside the body of the upper cavity can be observed in the process of adding the standby detection liquid to serve as the reference of the adding amount proportion. And then repeating the operation steps to make short contact with the glass fiber at the bottom of the second colloidal gold test strip, and judging the result according to the single and double lines on the test strip.
The micro-flow adjusting controller used in the device of the utility model can adopt the prior patent technology CN201921272293.3 as a high-safety transfusion flow adjuster.
The utility model discloses the device can repeatedly add and detect liquid dilution sample, carry out a lot of and detect, the integral operation is comparatively simple and convenient, high in practicability, through last cavity, micro-flow regulation controller, the liquid through hole of cavity and setting down, liquid conveying hose can realize that the accurate ration of sample liquid is carried and is detected, and conveniently carry, the sampling head of setting can increase the area of contact with the sample, reduce the difference that the sample inequality caused, avoid sample hemoglobin concentration too high to appear false negative's problem, it is more accurate to the detection of asphalt stool or fresh blood stool.
The specific type of the above-mentioned devices is not limited and detailed, and the deep connection mode of the above-mentioned devices is not detailed, and can be understood by those skilled in the art as the common general knowledge.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and should not be taken as limiting the scope of the present invention, and any modifications, equivalent replacements, and improvements made within the spirit and principle of the present invention should be included in the scope of the present invention.
Claims (10)
1. A portable fecal occult blood detection device comprises a micro-flow regulation controller, and is characterized by also comprising an upper cavity and a lower cavity; the upper cavity is internally pre-filled with detection liquid and is matched with an acquisition component; a liquid through hole is formed in the joint of the micro-flow regulation controller and the upper cavity, and a liquid conveying hose communicated with the liquid through hole is arranged at the joint of the micro-flow regulation controller and the lower cavity; the lower cavity body is internally provided with a plurality of colloidal gold test strips with clamping grooves, and rectangular small holes are formed in the bottoms of the clamping grooves.
2. The portable fecal occult blood detection device according to claim 1, wherein the collection component comprises a sampling rod and a sampling head integrated with a screw cap, and the sampling rod and the sampling head are screwed to be opened and closed with the bottleneck of the upper cavity body through the screw cap.
3. The portable fecal occult blood detection device of claim 2 wherein the sampling wand shaft is telescoping and the sampling head is removable.
4. The portable fecal occult blood testing device of claim 2 wherein the sampling head is a smooth geometry or a geometry with dense well-like concave strips on the body.
5. The portable fecal occult blood detection device according to claim 4, wherein the geometric body is any one of an ellipsoid, a cuboid and a cube.
6. The portable fecal occult blood detection device according to claim 1, wherein the colloidal gold test strips are not consistent in height and are staggered up and down, and the two test strips are separated by a distance of at least half the length of the test strip.
7. The portable fecal occult blood detection apparatus according to claim 1 or 6, wherein the top end of the liquid delivery hose is provided with a water permeable film with a pore size not less than 0.8 μm, the water permeable film is a polypropylene filter membrane.
8. The portable fecal occult blood detection device according to claim 1, wherein the device further comprises a standby detection liquid, and a drying sheet is further provided at the connection of the micro-flow regulating controller and the lower cavity.
9. The portable fecal occult blood detection device according to claim 1, wherein the liquid delivery hose, the upper cavity and the lower cavity are made of transparent PET plastic, and the upper cavity and the lower cavity are provided with digital scale lines.
10. The portable fecal occult blood detection device according to claim 1 or 8, wherein the detection liquid is distilled water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222045262.2U CN218382843U (en) | 2022-08-04 | 2022-08-04 | Portable fecal occult blood detection device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222045262.2U CN218382843U (en) | 2022-08-04 | 2022-08-04 | Portable fecal occult blood detection device |
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| Publication Number | Publication Date |
|---|---|
| CN218382843U true CN218382843U (en) | 2023-01-24 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202222045262.2U Active CN218382843U (en) | 2022-08-04 | 2022-08-04 | Portable fecal occult blood detection device |
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| Country | Link |
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| CN (1) | CN218382843U (en) |
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- 2022-08-04 CN CN202222045262.2U patent/CN218382843U/en active Active
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