CN218345368U

CN218345368U - Impurity removing device for heparin sodium preparation

Info

Publication number: CN218345368U
Application number: CN202222488968.6U
Authority: CN
Inventors: 余兰勇; 余艳
Original assignee: Xinyang Pingqiao Xinyi Casing Technology Co ltd
Current assignee: Xinyang Pingqiao Xinyi Casing Technology Co ltd
Priority date: 2022-09-20
Filing date: 2022-09-20
Publication date: 2023-01-20
Anticipated expiration: 2032-09-20

Abstract

The utility model provides an edulcoration device is used in heparin sodium preparation belongs to heparin sodium preparation technical field, including the box, the inside of box from top to bottom divide into filtration region, stirring region, ejection of compact region, and the inside of box is connected with first filter screen and filter, and one side top of box is connected with the inlet pipe that the slope set up, and the one end of inlet pipe is connected with the feeder hopper, and first filter screen is located between filtration region and the stirring region, and the filter is located between stirring region and the ejection of compact region; the utility model discloses heparin sodium can remove the graininess impurity therein through filtering area, carries out the first filtration to heparin sodium, and heparin sodium is located the stirring region and handles miscellaneous protein and microorganism wherein through adding chemical reagent, handles the impurity in the heparin sodium, and the heparin sodium after the stirring carries out secondary filter to it through the filter to guaranteed heparin sodium's purity, made heparin sodium edulcoration's effect better.

Description

Impurity removing device for heparin sodium preparation

Technical Field

The utility model relates to a heparin sodium preparation technical field, concretely relates to edulcoration device is used in preparation of heparin sodium.

Background

Heparin sodium is widely present in liver, lung and intestinal mucosa of mammals and is mostly combined with protein to form a complex, while crude heparin sodium is extracted from heparin raw materials to obtain small intestinal mucosa of healthy live pigs, and cannot be directly used due to the fact that the heparin sodium contains a large amount of impurities such as protein, microorganisms and the like.

The impurity removal equipment for crude heparin sodium used at present removes impurities by a chemical method, adds a chemical preparation into the heparin sodium, processes impurity proteins and microorganisms in the heparin sodium, and then filters the heparin sodium.

SUMMERY OF THE UTILITY MODEL

In view of this, the utility model provides an edulcoration device is used in heparin sodium preparation not only can stir heparin sodium, makes heparin sodium and chemical reagent mix more fully, but also can realize carrying out twice filtration to heparin sodium, makes heparin sodium purity better.

In order to solve the technical problem, the utility model provides an impurity removing device for heparin sodium preparation, which comprises a box body, wherein the interior of the box body is divided into a filtering area, a stirring area and a discharging area from top to bottom;

first filter screen is located between filtering area and the stirring region, the filter is located between stirring region and the ejection of compact region, the box top is connected with the motor, be connected with the pivot that runs through the box on the motor, the pivot extend to in the stirring region and contact with the filter, the pivot be connected with a plurality of (mixing) shafts, the lower extreme of pivot is connected with the stirring piece with the filter contact, the internal connection in ejection of compact region is used for realizing the drive assembly to the filter switch.

Furthermore, a push rod connected to the rotating shaft and in contact with the first filter screen is connected to the filter area.

Further, first filter screen is the back taper setting, the setting of push rod slope corresponds with first filter screen.

Further, set up a plurality of round holes that equidistant setting on the filter, be connected with the second filter screen on the round hole, the filter is protruding form circular arc setting, the below adaptation of stirring piece.

Furthermore, the driving assembly comprises an output shaft penetrating through the bottom of the box body, a baffle corresponding to the filter plate is connected to the upper end of the output shaft, through holes corresponding to the round holes are formed in the baffle, and the round holes and the through holes are arranged in a staggered mode.

Further, the bottom of the box body is obliquely arranged from the center of the box body to the edge of the box body from high to low.

Furthermore, the bottom of the box body is connected with a protective sleeve which is sleeved on the output shaft.

Further, the stirring sheet is obliquely arranged.

The utility model discloses an above-mentioned technical scheme's beneficial effect as follows:

1. the heparin sodium can remove granular impurities in the heparin sodium through the filtering area, the heparin sodium is filtered for the first time, the heparin sodium is positioned in the stirring area, the foreign proteins and microorganisms in the heparin sodium are treated by adding chemical reagents, the impurities in the heparin sodium are treated, and the stirred heparin sodium is filtered for the second time through the filtering plate, so that the purity of the heparin sodium is ensured, and the impurity removing effect of the heparin sodium is better.

2. Utilize the push rod to make heparin sodium flow on first filter screen fast, carry out better filtration to heparin sodium, in order to make heparin sodium flow to the edge of box and enter into the third discharging tube, so first filter screen adopts the back taper setting, and the elasticity scraper blade can reduce the friction of push rod and filter in addition, makes better the filtering from first filter screen of heparin sodium go out.

3. Be convenient for flow from the filter for heparin sodium, so set up the round hole of installation second filter screen on the filter, drive assembly's setting can be controlled the switch of round hole, avoids when stirring heparin sodium, and heparin sodium directly enters into the mixing stirring that influences heparin sodium in the ejection of compact region.

4. Discharge in order to make the good heparin sodium of handling enter into the second discharging pipe fast from the box, so the bottom of box is from the center of box to box edge by high to low, and wherein, the setting up of protective sheath can avoid heparin sodium to follow the output shaft and reveal away from the box.

Drawings

FIG. 1 is a schematic perspective view of the structure of the case of the present invention;

FIG. 2 is a schematic sectional view of the structure of the case of the present invention;

fig. 3 is a schematic perspective view of the structure of the filter plate of the present invention;

fig. 4 is a schematic perspective view of the structure of the stirring plate of the present invention.

In the figure: 1. a box body; 2. a motor; 3. a rotating shaft; 4. a stirring shaft; 5. a filter plate; 6. a stirring sheet; 7. a baffle plate; 8. an output shaft; 9. a first filter screen; 10. a push rod; 11. a feed pipe; 12. a feed hopper; 13. a first discharge pipe; 14. a second discharge pipe; 15. a third discharge pipe; 16. a protective sleeve; 51. a circular hole; 52. a second filter.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to fig. 1 to 4 of the embodiments of the present invention. It is to be understood that the embodiments described are only some of the embodiments of the present invention, and not all of them. All other embodiments, which can be derived from the description of the embodiments of the present invention by a person skilled in the art, are within the scope of the present invention.

Example one

As shown in fig. 1 and 2: an impurity removing device for heparin sodium preparation comprises a box body 1, wherein the interior of the box body 1 is divided into a filtering area, a stirring area and a discharging area from top to bottom, a first filter screen 9 and a filter plate 5 are connected to the interior of the box body 1, an obliquely arranged feeding pipe 11 is connected to the upper portion of one side of the box body 1, one end of the feeding pipe 11 is connected with a feeding hopper 12, and a first discharging pipe 13, a second discharging pipe 14 and a third discharging pipe 15 which are connected to the box body 1 are respectively arranged in the filtering area, the stirring area and the discharging area;

first filter screen 9 is located between filtering area and the stirring region, filter 5 is located between stirring region and the ejection of compact region, 1 top of box is connected with motor 2, be connected with pivot 3 that runs through box 1 on the motor 2, pivot 3 extend to in the stirring region and contact with filter 5, pivot 3 be connected with a plurality of (mixing) shafts 4, the lower extreme of pivot 3 is connected with the stirring piece 6 with 5 contacts of filter, the internal connection of ejection of compact region is used for realizing the drive assembly to the 5 switches of filter.

In this embodiment, heparin sodium can remove particulate impurity therein through the filtering area, carries out the first filtration to heparin sodium, and heparin sodium is located the stirring region and handles miscellaneous protein and microorganism wherein through adding chemical reagent, handles impurity in the heparin sodium, and the heparin sodium after the stirring carries out secondary filter through filter 5 to it to guaranteed the purity of heparin sodium, made the effect of heparin sodium edulcoration better.

Example two

As shown in fig. 2, the difference from the first embodiment is that: a push rod 10 which is connected on the rotating shaft 3 and is contacted with the first filter screen 9 is connected in the filtering area.

First filter screen 9 is the back taper setting, and the setting of push rod 10 slope corresponds with first filter screen 9, and the downside of push rod 10 is connected with the elasticity scraper blade.

In this embodiment, the push rod 10 can make the heparin sodium flow rapidly on the first filter 9, so as to perform better filtration on the heparin sodium.

Wherein, in order to make heparin sodium flow and enter into third discharging pipe 15 to the edge of box 1 in, so first filter screen 9 adopts the back taper setting, and the elasticity scraper blade can reduce the friction of push rod 10 and filter 5 in addition, makes better the filtering of first filter screen 9 of follow of heparin sodium go out.

EXAMPLE III

As shown in fig. 2, 3 and 4, the difference from the first embodiment is that: set up a plurality of round holes 51 that equidistant setting was seted up on the filter 5, be connected with second filter screen 52 on the round hole 51, the filter 5 is upwards protruding circular-arcly, can make the impurity in the heparin sodium flow from first discharging pipe 13 to 1 inner wall of box and flow.

Drive assembly is including the output shaft 8 who runs through 1 bottom of box, the bottom of box 1 is connected with the driving motor who is connected with

output shaft

8, 8 upper ends of output shaft are connected with the baffle 7 that corresponds with filter 5, set up the through-hole that corresponds with round hole 51 on the baffle 7, round hole 51 sets up with the through-hole is crisscross, stirring piece 6 slopes to set up, can make stirring piece 6 drive heparin sodium rebound, the heparin sodium of avoiding stirring regional bottom can't be put in place by stirring piece 6 stirring.

In this embodiment, the filter plate 5 is formed with a circular hole 51 for mounting the second filter 52 so that the heparin sodium can flow through the filter plate 5.

Wherein, drive assembly's setting can be controlled the switch of round hole 51, avoids when stirring heparin sodium, and heparin sodium directly enters into the regional mixed stirring that influences heparin sodium of ejection of compact.

Example four

As shown in fig. 2, the difference from the first embodiment is that: the bottom of the case 1 is inclined from high to low from the center of the case 1 to the edge of the case 1.

The bottom of the box body 1 is also connected with a protective sleeve 16 which is sleeved on the output shaft 8.

In this embodiment, in order to enable the treated heparin sodium to rapidly enter the second discharging pipe 14 and be discharged from the box body 1, the bottom of the box body 1 is obliquely arranged, wherein the protective sleeve 16 is arranged to prevent the heparin sodium from leaking out of the box body 1 along with the output shaft 8.

The utility model discloses a working method:

heparin sodium enters into box 1 and the contact of first filter screen 9 from feeder hopper 12 and inlet pipe 11, motor 2 drives the push rod 10 rotation in the pivot 3 simultaneously, accelerate heparin sodium to pass through from first filter screen 9, granular impurity to in the heparin sodium gets rid of, heparin sodium enters into in the stirring area this moment, add chemical through (mixing) shaft 4 effect simultaneously and mix with heparin sodium, handle hetero-protein and microorganism to in the heparin sodium, after heparin sodium stirs a period, output shaft 8 rotates and drives baffle 7 and open round hole 51 on the filter 5, heparin sodium passes through from second filter screen 52 through round hole 51, filter heparin sodium once more, the heparin sodium that enters into the ejection of compact region is discharged from box 1 from second discharging pipe 14.

In the present invention, unless otherwise explicitly specified or limited, for example, it may be fixedly connected, detachably connected, or integrated; can be mechanically or electrically connected; they may be directly connected or indirectly connected through an intermediate medium, and may be connected through the inside of two elements or in an interaction relationship between two elements, unless otherwise specifically defined, and the specific meaning of the above terms in the present invention will be understood by those skilled in the art according to specific situations.

The foregoing is a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of improvements and embellishments can be made without departing from the principle of the present invention, and these improvements and embellishments should also be regarded as the protection scope of the present invention.

Claims

1. The utility model provides a heparin sodium preparation is with edulcoration device, includes box (1), its characterized in that: the interior of the box body (1) is divided into a filtering area, a stirring area and a discharging area from top to bottom, a first filter screen (9) and a filter plate (5) are connected with the interior of the box body (1), a feeding pipe (11) which is obliquely arranged is connected above one side of the box body (1), and one end of the feeding pipe (11) is connected with a feeding hopper (12);

first filter screen (9) are located between filtering area and the stirring region, filter (5) are located between stirring region and the ejection of compact region, box (1) top is connected with motor (2), be connected with pivot (3) that run through box (1) on motor (2), pivot (3) extend to stirring region in and contact with filter (5), being connected with a plurality of (mixing) shafts (4) of pivot (3), the lower extreme of pivot (3) is connected with stirring piece (6) with filter (5) contact, the internal connection in ejection of compact region is used for realizing the drive assembly to filter (5) switch.

2. The impurity removing device for heparin sodium preparation according to claim 1, wherein: a push rod (10) which is connected to the rotating shaft (3) and is contacted with the first filter screen (9) is connected in the filtering area.

3. The impurity removing device for heparin sodium preparation according to claim 2, wherein: first filter screen (9) are the back taper setting, push rod (10) slope setting corresponds with first filter screen (9).

4. The impurity removing device for heparin sodium preparation according to claim 1, wherein: set up a plurality of round holes (51) that equidistant setting was seted up on filter (5), be connected with second filter screen (52) on round hole (51), filter (5) are protruding form circular arc setting, the below adaptation of stirring piece (6).

5. The impurity removing device for heparin sodium preparation according to claim 4, wherein: the driving assembly comprises an output shaft (8) penetrating through the bottom of the box body (1), a baffle (7) corresponding to the filter plate (5) is connected to the upper end of the output shaft (8), a through hole corresponding to the round hole (51) is formed in the baffle (7), and the round hole (51) and the through hole are arranged in a staggered mode.

6. The impurity removing device for heparin sodium preparation according to claim 1, wherein: the bottom of the box body (1) is obliquely arranged from the center of the box body (1) to the edge of the box body (1) from high to low.

7. The impurity removing device for heparin sodium preparation according to claim 1, wherein: the bottom of the box body (1) is connected with a protective sleeve (16) which is sleeved on the output shaft (8).

8. The impurity removing device for heparin sodium preparation according to claim 1, wherein: the stirring sheet (6) is obliquely arranged.