CN218331583U - Rapid detection reagent card for rapid detection of fluorescent microspheres - Google Patents

Rapid detection reagent card for rapid detection of fluorescent microspheres Download PDF

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Publication number
CN218331583U
CN218331583U CN202221594243.9U CN202221594243U CN218331583U CN 218331583 U CN218331583 U CN 218331583U CN 202221594243 U CN202221594243 U CN 202221594243U CN 218331583 U CN218331583 U CN 218331583U
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China
Prior art keywords
rapid detection
detection
pad
reagent card
reagent
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CN202221594243.9U
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Chinese (zh)
Inventor
苗银萍
瞿超杰
曾小宇
付燕峰
赵林萍
郭旭光
赵光升
娄亚坤
李宁
任宝红
杨楠
许红超
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Henan Institute Of Food Inspection
Xinxiang City Won Bid Of Inspection And Quarantine Innovation Research Institute
Zhongbiao Testing Henan Service Ltd
Zhengzhou Zhongdao Biotechnology Co ltd
Original Assignee
Henan Institute Of Food Inspection
Xinxiang City Won Bid Of Inspection And Quarantine Innovation Research Institute
Zhongbiao Testing Henan Service Ltd
Zhengzhou Zhongdao Biotechnology Co ltd
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Application filed by Henan Institute Of Food Inspection, Xinxiang City Won Bid Of Inspection And Quarantine Innovation Research Institute, Zhongbiao Testing Henan Service Ltd, Zhengzhou Zhongdao Biotechnology Co ltd filed Critical Henan Institute Of Food Inspection
Priority to CN202221594243.9U priority Critical patent/CN218331583U/en
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Abstract

A rapid detection reagent card for rapid detection of fluorescent microspheres relates to the technical field of rapid detection of immunofluorescence microspheres and comprises a shell and reagent strips, wherein a partition plate is arranged in the shell, a placing plate is arranged in a detection cavity and connected to the top of the partition plate through an elastic component, a groove is formed in the top of the placing plate, clamping grooves for placing the reagent strips are formed in two ends of the groove, and a plurality of air holes are formed in the bottom of the groove and the partition plate respectively; after the reagent card is assembled, the drying agent is packaged into the drying cavity, and the reagent strip can be kept in a drying state for a long time in a normal-humidity environment, so that the influence of moisture absorption on the chromatography effect of the reagent strip is prevented; when the top cap lid closes at the detection chamber top, under the effect of elastic component elasticity reaction force, the top cap has played the effect that compresses tightly the reagent strip, makes inseparabler of contact between the gasket at reagent strip top, has improved detection efficiency.

Description

Rapid detection reagent card for rapid detection of fluorescent microspheres
Technical Field
The utility model relates to an immunofluorescence microballon short-term test technical field, concretely relates to short-term test reagent card that is used for fluorescence microballon to examine soon.
Background
When the immunofluorescence microsphere is rapidly detected, a reagent card is usually adopted, and the detection method needs to be convenient, accurate, reliable, cheap and simple to operate.
The existing rapid test reagent card has the following defects: (1) The existing reagent shell is mostly fixed, so that reagent strips are inconvenient to replace, the reagent shell is a disposable consumable, resource waste is caused, and environmental pollution is easily caused due to the fact that the reagent shell is a plastic product; (2) The existing reagent shell has a simple structure, is directly exposed and packaged when in use, cannot be protected best when in storage, and can cause the reagent card to be affected with damp when meeting a humid environment, thereby influencing the detection result of the reagent card; (3) The existing reagent card has the problems that the gaskets are not firm to fix and the contact between the gaskets is not tight enough, so that the detection speed and the accuracy of a result are influenced.
SUMMERY OF THE UTILITY MODEL
To the problem that exists, the utility model provides a short-term test reagent card for fluorescence microballon examines soon.
The specific technical scheme is as follows: including the casing with be used for immunofluorescence microballon short-term test's reagent strip, the inside of casing is provided with the division board, the division board will detection chamber and dry chamber are split into to the casing, it places the board to detect intracavity portion, it connects through elastic component to place the board the top of division board, the top of placing the board is seted up flutedly, the both ends of recess are provided with and are used for placing the draw-in groove of reagent strip, the bottom of recess with a plurality of bleeder vents have all been seted up on the division board, the bottom surface sealing cover in dry chamber has closed the bottom, the top lid in detection chamber has closed the top cap, the top surface of top cap is provided with into appearance hole and observation window.
Preferably, the reagent strip comprises a bottom plate, a sample pad, a fluorescence pad, a detection pad and a water absorption pad are sequentially bonded on the bottom plate, and the detection pad is a nitrocellulose membrane.
Preferably, advance the appearance hole with the corresponding setting of sample pad, be funnel-shaped structure in the appearance hole, just advance appearance hole bottom cross sectional area and be less than the area of sample pad, the top surface of advance appearance hole is equipped with the joint limit, the outside joint on joint limit has and is used for the lid to close the handhole door of advance appearance hole, the handhole door passes through the connecting strip and connects on the top cap.
Preferably, the observation window and the detection pad are arranged correspondingly, the cross section area of the observation window is smaller than that of the detection pad, and a transparent panel is fixed in the observation window.
Preferably, the elastic component comprises a plurality of compression springs, and when the plurality of compression springs are in a static state, the top of the placing plate is higher than the top surface of the detection cavity.
Preferably, a plurality of partition plates are arranged in the drying cavity, the drying cavity is divided into a plurality of partition cavities for holding the desiccant bags by the partition plates, and the top surfaces of the partition plates are fixedly connected with the bottom surfaces of the partition plates.
Preferably, a first connecting groove is formed in the bottom surface of the shell, a first connecting block matched and clamped with the first connecting groove is arranged on the inner side wall of the bottom cover, a first sealing gasket is arranged in the first connecting groove, and the cross sectional area of the bottom cover is larger than that of the shell.
Preferably, the second spread groove has been seted up to the top surface of casing, the inside wall of top cap be provided with the second connecting block of second spread groove cooperation joint, the inside sealed pad of second that is provided with of second spread groove, the cross sectional area of top cap is greater than the cross sectional area of casing.
Preferably, the bottom of the groove is arranged corresponding to the air holes in the isolation plate.
Preferably, the top cover and the bottom cover are fixed by an elastic band.
The utility model provides a short-term test reagent card for fluorescent microsphere examines soon compares beneficial effect with prior art and is:
(1): the utility model facilitates the clamping and the disassembly of the reagent strip, is beneficial to the reutilization, can also carry out the quick replacement of the reagent strip, and is suitable for the quick, frequent and batch detection;
(2): the utility model is provided with the drying cavity, after the reagent card is assembled, the drying agent is packaged into the drying cavity, and the reagent strip can keep a longer drying state in a normal wet environment, thereby preventing the reagent strip from affecting the chromatography effect due to moisture absorption and reducing the detection error;
(3): the utility model discloses set up elastic component, close when detecting the chamber top at the top cap lid, under the effect of elastic component elasticity reaction force, the top cap has played the effect that compresses tightly the reagent strip, makes inseparabler of contact between the gasket at reagent strip top, has improved detection efficiency.
Drawings
FIG. 1: is the structure diagram of the whole structure of the utility model.
FIG. 2: is an enlarged view of a portion a in fig. 1.
FIG. 3: is the whole front view of the utility model.
FIG. 4 is a schematic view of: is the utility model discloses well casing does not add top cap state front view.
FIG. 5: is the top view of the middle placing plate of the utility model.
FIG. 6: is a schematic diagram of the reagent strip in the utility model.
In the figure: 1-shell, 2-isolation board, 3-detection cavity, 4-drying cavity, 5-placing board, 6-groove, 7-clamping groove, 8-air hole, 9-bottom cover, 10-top cover, 11-sample inlet hole, 12-observation window, 13-bottom board, 14-sample pad, 15-fluorescence pad, 16-detection pad, 17-water absorption pad, 18-clamping edge, 19-hole cover, 20-connecting strip, 21-panel, 22-compression spring, 23-first connecting groove, 24-first connecting block, 25-first sealing pad, 26-second connecting groove, 27-second connecting block, 28-second sealing pad, 29-elastic band and 30-baffle.
Detailed Description
The technical solutions of the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings, and it is to be understood that the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative efforts belong to the protection scope of the present invention, and in the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. indicate the orientation or position relationship based on the orientation or position relationship shown in the drawings, and are only for convenience of description of the present invention and simplifying the description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus cannot be understood as limiting the present invention.
Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance throughout the present disclosure, it being understood that unless otherwise expressly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly and can be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.
The present invention will be described in further detail below with reference to specific embodiments and with reference to the accompanying drawings.
The first embodiment is as follows: as shown in FIGS. 1 and 2, the rapid detection reagent card for rapid detection of fluorescent microspheres comprises a shell 1 and a reagent strip for rapid detection of immunofluorescent microspheres.
As shown in FIG. 6, the reagent strip comprises a bottom plate 13, the bottom plate 13 is made of PVC, and a sample pad 14, a fluorescence pad 15, a detection pad 16 and a water absorption pad 17 are sequentially adhered to the bottom plate 13 through glue. The structure of the reagent strip is similar to that of a test paper card in the patent with the application number of '201910427204.6' in the prior art, and specifically, the sample pad 14 is a dried glass cellulose membrane after being soaked in a sample pad treatment solution; a monoclonal antibody Mab1 of an epitope of the fluorescence labeling anti-ASFVp 30 antigen is arranged in the fluorescence pad 15, and the detection pad 16 is a nitrocellulose membrane; the absorbent pad 17 is absorbent filter paper.
Casing 1's inside is provided with division board 2, and division board 2 sets up with casing 1 integrated into one piece, and division board 2 is divided into casing 1 and is detected chamber 3 and dry chamber 4, detects the top that chamber 3 is located dry chamber 4.
Detect 3 inside being provided with in chamber and placing board 5, place board 5 and connect at the top of division board 2 through elastic component, elastic component includes a plurality of compression spring 22 in this embodiment, compression spring 22's both ends respectively with place board 5, 2 fixed connection of division board, the fixed connection of here can be for gluing. As shown in FIG. 4, when the compression springs 22 are in a static state, the top of the placing plate 5 is higher than the top surface of the detection chamber 3, and when the top cover 10 covers the top of the detection chamber 3, under the elastic reaction force of the compression springs 22, the top cover 10 plays a role of compressing the reagent strips, so that the contact between the gaskets at the top of the reagent strips is tighter, and the detection efficiency is improved.
As shown in figure 5, the top of placing board 5 is seted up flutedly 6, and the both ends of recess 6 are provided with the draw-in groove 7 that is used for placing the reagent strip, and draw-in groove 7 sets up with placing board 5 integrated into one piece, and draw-in groove 7 and the both ends size looks adaptation of reagent strip set up like this and make the reagent strip location inside recess 6, prevent that the reagent strip from moving about.
The drying chamber 4 is internally provided with a plurality of clapboards 30, the drying chamber 4 is divided into a plurality of separating cavities for placing drying agent bags by the plurality of clapboards 30, the top surfaces of the clapboards 30 are fixedly connected with the bottom surface of the isolation board 2, and the clapboards 30 can be integrally formed with the isolation board 2.
A plurality of air holes 8 are formed in the bottom of the groove 6 and the isolation plate 2, and the bottom of the groove 6 corresponds to the air holes 8 in the isolation plate 2.
After the reagent card is assembled, the drying agent is packaged into the separation cavity of the drying cavity 4, the reagent strips in the grooves 6 can be dried through the air holes 8, and the reagent strips can be kept in a dry state for a long time in a normal wet environment, so that the influence of moisture absorption on the chromatography effect of the reagent strips is prevented, and the detection error is reduced.
Bottom cover 9 has been closed to the sealed lid in bottom surface of dry chamber 4, first connecting groove 23 has been seted up to casing 1's bottom surface, bottom 9's inside wall is provided with the first splice block 24 with first connecting groove 23 cooperation joint, first splice block 24 sets up with bottom 9 integrated into one piece, bottom 9 cooperatees through first splice block 24 and first connecting groove 23 and seals dry chamber 4 bottom opening, and the cross sectional area of bottom 9 is greater than casing 1's cross sectional area, it conveniently opens bottom 9 to set up like this, and then conveniently changes the drier package that separates the intracavity, guarantee the drying effect of the inside reagent strip of casing 1.
The first sealing gasket 25 is arranged in the first connecting groove 23, the first sealing gasket 25 is made of rubber, and the sealing effect of the bottom cover 9 and the drying cavity 4 is improved by arranging the first sealing gasket 25.
Detect the top lid in chamber 3 and have closed top cap 10, second spread groove 26 has been seted up to casing 1's top surface, top cap 10's inside wall is provided with the second connecting block 27 with second spread groove 26 matched with joint, second connecting block 27 sets up with top cap 10 integrated into one piece, top cap 10 cooperatees through second connecting block 27 and second spread groove 26 and will detect chamber 3 open-top and seal, and the cross sectional area of top cap 10 is greater than casing 1's cross sectional area, it conveniently opens bottom 9 to set up like this, and then conveniently changes the reagent strips.
Inside second sealed pad 28 that is provided with of second spread groove 26, the sealed pad 28 that adopts the rubber material to make of second, through setting up the sealed pad 28 of second, increases top cap 10 and detection chamber 3's sealed effect, prevents effectively that external pollutant from getting into in the detection chamber 3, prevents that the reagent strip in the detection chamber 3 from polluting.
The top surface of the top cover 10 is provided with a sample inlet hole 11 and an observation window 12. Wherein, the sample inlet 11 is arranged corresponding to the sample pad 14, the sample inlet 11 is of a funnel-shaped structure, the cross-sectional area of the bottom of the sample inlet 11 is smaller than the area of the sample pad 14, the top surface of the sample inlet 11 is provided with a clamping edge 18, the clamping edge 18 and the top cover 10 are integrally formed, a hole cover 19 for covering the sample inlet 11 is clamped on the outer side of the clamping edge 18, a rubber sealing ring is arranged on the inner side of the hole cover 19, the sealing effect of the hole cover 19 and the sample inlet 11 is improved, the hole cover 19 is connected to the top cover 10 through a connecting strip 20, the connecting strip 20 is a plastic strip capable of being bent at will, two ends of the connecting strip 20 are respectively connected with the hole cover 19 and the top cover 10 in a gluing mode, the hole cover 19 is arranged, when the reagent card is not used, the sample inlet 11 is sealed, the reagent strip inside the protection shell 1 is not polluted, the connecting strip 20 is arranged, and the hole cover 19 is prevented from being lost.
The observation window 12 is arranged corresponding to the detection pad 16, the cross section area of the observation window 12 is smaller than the area of the detection pad 16, a transparent panel 21 is fixed in the observation window 12, the panel 21 is fixed in the observation window 12 through glue, and the panel 21 is arranged, so that on one hand, observation is facilitated, and on the other hand, the sealing of the observation window 12 can also be realized.
Example two: in addition to the first embodiment, as shown in fig. 3, the top cover 10 and the bottom cover 9 are fixed by the elastic bands 29, and after the reagent card is assembled, the elastic bands 29 are sleeved on two ends of the reagent card to fixedly connect the reagent card, so as to prevent the top cover 10 and the bottom cover 9 on the upper and lower sides of the reagent card from being separated from the housing 1.
To sum up, the utility model discloses make things convenient for the reagent strip to carry out the clamping and dismantle, be favorable to reuse, can also carry out quick replacement to the reagent strip, be fit for being used for quick, frequent, detection in batches.
While the present invention has been particularly shown and described with reference to the preferred embodiments thereof, and many methods and approaches to the practice thereof, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the present invention as defined by the appended claims.

Claims (10)

1. A short-term test reagent card for fluorescence microballon short-term test, including casing (1) and the reagent strip that is used for immunofluorescence microballon short-term test, its characterized in that, the inside of casing (1) is provided with division board (2), division board (2) will detection chamber (3) and dry chamber (4) are split into in casing (1), it places board (5) to detect inside being provided with of chamber (3), place board (5) and connect through elastic component the top of division board (2), the top of placing board (5) is seted up flutedly (6), the both ends of recess (6) are provided with and are used for placing draw-in groove (7) of reagent strip, the bottom of recess (6) with all seted up a plurality of bleeder vents (8) on division board (2), the bottom surface sealing cover of dry chamber (4) has closed bottom (9), the top cover of detection chamber (3) has closed top cap (10), the top surface of top cap (10) is provided with into appearance hole (11) and observation window (12).
2. The rapid detection reagent card for rapid detection of fluorescent microspheres according to claim 1, wherein the reagent strip comprises a bottom plate (13), a sample pad (14), a fluorescent pad (15), a detection pad (16) and a water absorption pad (17) are sequentially bonded on the bottom plate (13), and the detection pad (16) is a nitrocellulose membrane.
3. The rapid detection reagent card for the fluorescent microsphere rapid detection according to claim 2, wherein the sample inlet (11) is arranged corresponding to the sample pad (14), the sample inlet (11) is internally provided with a funnel-shaped structure, the cross-sectional area of the bottom of the sample inlet (11) is smaller than the area of the sample pad (14), the top surface of the sample inlet (11) is provided with a clamping edge (18), the outer side of the clamping edge (18) is clamped with a hole cover (19) for covering the sample inlet (11), and the hole cover (19) is connected to the top cover (10) through a connecting strip (20).
4. The rapid detection reagent card for rapid detection of fluorescent microspheres according to claim 2, wherein the observation window (12) is disposed corresponding to the detection pad (16), the cross-sectional area of the observation window (12) is smaller than the area of the detection pad (16), and a transparent panel (21) is fixed in the observation window (12).
5. The rapid detection reagent card for rapid detection of fluorescent microspheres according to claim 1, wherein the elastic component comprises a plurality of compression springs (22), and the top of the placing plate (5) is higher than the top surface of the detection chamber (3) when the plurality of compression springs (22) are in a static state.
6. The rapid detection reagent card for fluorescent microsphere rapid detection according to claim 1, wherein a plurality of partition boards (30) are arranged inside the drying cavity (4), the drying cavity (4) is divided into a plurality of separate cavities for placing desiccant bags by the plurality of partition boards (30), and the top surfaces of the partition boards (30) are fixedly connected with the bottom surface of the partition board (2).
7. The rapid detection reagent card for the fluorescent microsphere rapid detection according to claim 1, wherein a first connecting groove (23) is formed in the bottom surface of the housing (1), a first connecting block (24) which is matched and clamped with the first connecting groove (23) is arranged on the inner side wall of the bottom cover (9), a first sealing gasket (25) is arranged inside the first connecting groove (23), and the cross sectional area of the bottom cover (9) is larger than that of the housing (1).
8. The rapid detection reagent card for the fluorescent microsphere rapid detection according to claim 1, wherein a second connecting groove (26) is formed in the top surface of the housing (1), a second connecting block (27) which is matched and clamped with the second connecting groove (26) is arranged on the inner side wall of the top cover (10), a second sealing gasket (28) is arranged inside the second connecting groove (26), and the cross sectional area of the top cover (10) is larger than that of the housing (1).
9. The rapid detection reagent card for the rapid detection of the fluorescent microspheres according to claim 1, wherein the bottom of the groove (6) is arranged corresponding to the air holes (8) on the isolation plate (2).
10. The rapid detection reagent card for rapid detection of fluorescent microspheres according to claim 1, wherein the top cover (10) and the bottom cover (9) are fixed by an elastic band (29).
CN202221594243.9U 2022-06-24 2022-06-24 Rapid detection reagent card for rapid detection of fluorescent microspheres Active CN218331583U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202221594243.9U CN218331583U (en) 2022-06-24 2022-06-24 Rapid detection reagent card for rapid detection of fluorescent microspheres

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202221594243.9U CN218331583U (en) 2022-06-24 2022-06-24 Rapid detection reagent card for rapid detection of fluorescent microspheres

Publications (1)

Publication Number Publication Date
CN218331583U true CN218331583U (en) 2023-01-17

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ID=84868984

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202221594243.9U Active CN218331583U (en) 2022-06-24 2022-06-24 Rapid detection reagent card for rapid detection of fluorescent microspheres

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CN (1) CN218331583U (en)

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