CN218306314U - Special processing rack for detecting urovanillic mandelic acid by anion exchange resin column - Google Patents

Special processing rack for detecting urovanillic mandelic acid by anion exchange resin column Download PDF

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Publication number
CN218306314U
CN218306314U CN202222707523.2U CN202222707523U CN218306314U CN 218306314 U CN218306314 U CN 218306314U CN 202222707523 U CN202222707523 U CN 202222707523U CN 218306314 U CN218306314 U CN 218306314U
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hole
plate
section
exchange resin
anion exchange
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Chinese (zh)
Inventor
董作亮
李江
李聪新
黄毅文
董莉真
李津鸿
张妍
胡志东
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Tianjin Medical University General Hospital
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Tianjin Medical University General Hospital
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Abstract

The utility model provides a special processing frame for detecting the mandelic acid in the urine vanilla by an anion exchange resin column, which comprises a bottom plate and vertical plates vertically connected with the left and right side ends of the bottom plate; the collecting tank is arranged at the lower part of the main body frame and can be put in or taken out in a drawing way from the front side inlet and outlet; the middle layer plate and the upper layer plate are respectively positioned at the middle part and the top part of the main body frame, a gap is reserved between the middle layer plate and the upper layer plate, a plurality of middle layer column pipe through holes and upper layer column pipe through holes are arranged on the middle layer plate and the upper layer plate in a one-to-one correspondence mode, column pipes of each anion exchange resin column sequentially penetrate through the upper layer column pipe through holes of the upper layer plate and the middle layer column pipe through holes of the middle layer plate, and the pipe nozzle section faces towards the collecting tank. The utility model has simple structure and convenient processing; the vertical stability of the column tube on the processing frame is effectively ensured, and the operations of disassembly, assembly, processing and cleaning are facilitated; can gather and collect the overflowing and leaking liquid in the treatment process, effectively reduce the possibility of polluting the operation area and ensure the biological safety to the maximum extent.

Description

Special processing rack for detecting urovanillic mandelic acid by anion exchange resin column
Technical Field
The utility model belongs to the field of medical equipment, especially, relate to urine vanillic mandelic acid detects and handles frame with anion exchange resin post special use.
Background
The urovanillylmandelic acid (VMA) assay can help to understand the secretion level of catecholamine in vivo, and has important diagnostic significance for patients with hypertension, especially young people with wide blood pressure fluctuation range and no kidney diseases. In the manual detection method of urine vanillylmandelic acid, an anion exchange resin column is used for processing a urine sample, as shown in figure 1, a column tube 1 of the anion exchange resin column is provided with a large-diameter section 11, a small-diameter section 13 and a nozzle section 15 with different upper and lower tube diameters, a first conical transition section 12 and a second conical transition section 14 are formed between the two adjacent sections, a common test tube rack is used for loading the column, the column tube is not easy to keep vertical stability, the processing operation is not facilitated, and the possibility of polluting an operation area caused by urine, elution reagent overflow, dripping leakage and the like in the processing process exists.
Disclosure of Invention
In view of this, the utility model aims at overcoming the defects in the prior art and providing a special treatment frame for detecting urovanillyl mandelic acid by using an anion exchange resin column.
In order to achieve the above purpose, the technical scheme of the utility model is realized as follows:
urine vanillic mandelic acid detects with special processing frame of anion exchange resin post, includes:
the main body frame is integrally in a model of 21274and consists of a bottom plate and vertical plates vertically connected with the left and right side ends of the bottom plate;
the collecting tank is arranged at the lower part of the main body frame and can be put in or taken out from the front side inlet and outlet of the main body frame in a drawing way;
the middle layer plate and the upper layer plate are respectively positioned at the middle part and the top part of the main body frame, are parallel to each other, and are provided with gaps, a plurality of middle layer column pipe through holes and upper layer column pipe through holes are arranged on the middle layer plate and the upper layer plate in a one-to-one correspondence mode, column pipes of each anion exchange resin column sequentially penetrate through the upper layer column pipe through holes of the upper layer plate and the middle layer column pipe through holes of the middle layer plate, and the pipe nozzle sections face the collecting tank.
The collecting groove is located above the bottom plate and between the vertical plates on the left side and the right side, and the middle plate and the upper plate are located between the vertical plates on the two sides and located in the middle and at the top of the position right above the collecting groove respectively.
The minimum aperture of the upper-layer column tube through hole is larger than the maximum outer diameter of the small-diameter section of the column tube and smaller than the minimum outer diameter of the large-diameter section.
The minimum aperture of the middle-layer column tube through hole is larger than the maximum outer diameter of the nozzle section of the column tube and smaller than the minimum outer diameter of the small-diameter section.
The upper layer column tube through hole of the upper layer plate penetrates through and is sleeved with and bears a first transition section of the limiting column tube, and the middle layer column tube through hole of the middle layer plate penetrates through and is sleeved with and bears a second transition section of the limiting column tube.
The upper-layer column pipe through hole is set to be of a step hole structure and is a step hole with a large hole section below an upper small hole section, at least one runner groove is further formed in the inner hole wall surface of the small hole section, the upper end of the runner groove is communicated to the step surface between the large hole section and the small hole section, and the lower end of the runner groove is communicated to the orifice end surface below the small hole section.
The middle-layer column tube through hole is set to be a step hole structure, the step hole is provided with a large hole section below an upper small hole section, at least one runner groove is further arranged on the inner wall surface of the small hole section, the upper end of the runner groove is communicated to the step surface between the large hole section and the small hole section, and the lower end of the runner groove is communicated to the orifice end surface below the small hole section.
The opposite faces of the vertical plates on the two sides are respectively provided with a bearing strip for bearing the corresponding ends of the upper plate and the middle plate, and the middle plate and the upper plate can be put in or taken out in a pull-out manner along the corresponding bearing strips.
A first stopping part is convexly arranged at the tail end of the bearing strip on the vertical plate on one side, and a corresponding stopping notch is formed in the corresponding position of the upper layer plate and the middle layer plate; a second stopping part is convexly arranged at the connecting corner of the vertical plate and the bottom plate, and a stopping recess is correspondingly arranged on the collecting tank.
The collecting tank is also provided with a pouring mouth part and a handle part respectively.
Compared with the prior art, the utility model discloses following advantage has:
the utility model has simple structure and convenient processing; the vertical stability of the column tube on the processing frame is effectively ensured, and the operations of disassembly, assembly, processing and cleaning are facilitated; can gather together, collect excessive, the dribbling liquid in the processing procedure, effectively reduce the possibility of polluting the operation area, furthest's assurance biosafety.
Drawings
The accompanying drawings, which form a part of the present disclosure, are included to provide a further understanding of the present disclosure, and are incorporated in and constitute a part of this specification, illustrate embodiments of the present disclosure and together with the description serve to explain the present disclosure. In the drawings:
FIG. 1 is a schematic view of the structure of a column tube of an anion exchange resin according to the present invention;
FIG. 2 is a perspective view illustrating the usage state of the present invention;
fig. 3 is an exploded view of the present invention;
FIG. 4 is a schematic perspective view of a holding tank;
fig. 5 is a partial sectional view of the present invention;
FIG. 6 is an enlarged view of portion A of FIG. 5;
fig. 7 is an enlarged view of part B of fig. 5.
Description of reference numerals:
a column tube 1; a coarse diameter section 11; a first transition section 12; a small diameter section 13; a second transition section 14; a nozzle section 15;
a main body frame 2; a base plate 20; a vertical plate 21; a second stopper portion 201; a support strip 211; a first stopper portion 212;
an upper plate 3; an upper-layer pillar tube through-hole 31; a stop notch 32; a macroporous section 311; a small bore section 312; a runner groove 313; a step surface 314;
a middle layer plate 4; a middle-layer column tube through hole 41; a stop notch 42; a macroporous section 411; a small bore section 412; a runner groove 413; a step surface 414;
a collecting tank 5; a pouring spout 51; a handle portion 52; the stop recess 53.
Detailed Description
It should be noted that, in the present invention, the embodiments and features of the embodiments may be combined with each other without conflict.
The present invention will be described in detail below with reference to the accompanying drawings in conjunction with embodiments.
The main body frame 2 is a frame body in a shape of a letter 21274as a whole and consists of a bottom plate 20 and vertical plates 21 vertically connected to the left side end and the right side end of the bottom plate 20; the lower part of the main body frame 2, namely the collecting groove 5 which is positioned above the bottom plate 20 and between the vertical plates 21 at the left and right sides and used for collecting overflowing or dripping urine and eluting reagents is accommodated, and the collecting groove can be put in or taken out in a drawing mode from the front side inlet and outlet of the main body frame 2.
At the middle part and the top of main part frame, it is specific that be equipped with well plywood 4 and upper plate 3 respectively at the middle part and the top that lie in directly over collecting vat 5 between the vertical board 21 of both sides, well plywood 4 and upper plate 3 are parallel to each other and leave the clearance each other, set up a plurality of middle level post pipe through-holes 41 of position one-to-one on well plywood 4 and the upper plate 3, upper column pipe through-hole 31, the post pipe 1 of every anion exchange resin post passes through upper column pipe through-hole 31 of upper plate 3 in proper order, the middle level post pipe through-hole 41 of middle plywood 4, mouthpiece section 15 is towards collecting vat 5.
As can be seen from fig. 1, the maximum pipe diameters of the large diameter section 11, the first transition section 12, the small diameter section 13, the second transition section 14, and the nozzle section 15 of the column tube 1 are sequentially reduced, and the minimum pipe diameters are also sequentially reduced, so that the column tube can penetrate through the column tube and can be supported at corresponding positions of the column tube in a limiting manner, at least the following conditions are satisfied:
the minimum aperture of the upper-layer column tube through hole 31 is larger than the maximum outer diameter of the small-diameter section 13 of the column tube and smaller than the minimum outer diameter of the large-diameter section 11; through the structural design, the upper-layer column pipe through hole 31 can smoothly pass through the small-diameter section and the column pipe part below the small-diameter section, but cannot pass through the large-diameter section 11;
the minimum aperture of the middle-layer pillar tube through hole 41 is larger than the maximum outer diameter of the nozzle section 15 of the pillar tube and smaller than the minimum outer diameter of the small-diameter section 13; through this structural design, it is convenient for the middle layer pillar tube through-hole 41 to be able to pass through the nozzle section 15 smoothly, but not to pass through the small diameter section 13.
As can be seen from fig. 5, preferably, the upper-layer pillar tube through hole 31 of the upper-layer plate 3 passes through the first transition section 12 of the sleeved pillar tube 1, and thus supports and limits the first transition section 12; the middle layer column tube through hole 41 of the middle layer plate 4 passes through the second transition section 14 of the sleeved column tube 1, and thus, the second transition section 14 is supported and limited. Through above-mentioned connection structure, every column pipe is cup jointed spacingly respectively by upper plate 3 and middle plate 4 of below, has effectively ensured the column pipe and has handled the perpendicular stability on putting up, has made things convenient for processing operation.
Furthermore, the upper-layer column tube through hole 31 and the middle-layer column tube through hole 41 can be respectively provided with a step hole structure, the upper-layer column tube through hole and the middle-layer column tube through hole are step holes with a large hole section below and a small hole section below, at least one runner groove is further arranged on the inner wall surface of the small hole section, the upper end of the runner groove is communicated to the step surface between the large hole section and the small hole section, and the lower end of the runner groove is communicated to the orifice end surface below the small hole section.
The utility model provides two kinds of embodiments of step hole, as shown in fig. 6, the upper layer pillar through hole 31 of the upper plate is taken as an example, in this embodiment, the large hole section 311 of the step hole is a cylindrical hole, the small hole section 312 is a tapered hole, the runner groove 313 is arranged along the inner wall surface of the small hole section 312, the upper end of the runner groove 313 is communicated to the step surface 314 between the large hole section and the small hole section, and the lower end is communicated to the orifice end surface below the small hole section 312; as shown in fig. 7, for example, the middle layer pillar via hole 31 of the middle layer plate, in this embodiment, the large hole section 411 and the small hole section 412 of the stepped hole are cylindrical holes, the flow channel groove 413 is opened along the inner wall surface of the small hole section 412, the upper end of the flow channel groove 413 is connected to the stepped surface 414 between the large hole section and the small hole section, and the lower end is connected to the end surface of the hole below the small hole section 412.
The structure scheme that the stepped hole and the flow channel groove which is communicated up and down are arranged on the inner wall surface of the hole of the small hole section is adopted, so that after the bearing column tube is sleeved, an annular gathering groove is formed between the large hole section and the outer tube surface of the column tube, the gathering groove is favorable for collecting, gathering and dripping polluted liquid which overflows and flows down along the tube wall, the polluted liquid is smoothly guided to flow down by the flow channel groove, and pollution expansion is further prevented.
For convenience of processing and cleaning, the upper plate 3, the middle plate 4 and the collecting tank 5 can be detachable from the main frame, as shown in fig. 3, the two side vertical plates 21 are respectively provided with a bearing strip 211 for bearing the corresponding end of the upper plate 3 and the middle plate 4 on the opposite plate surfaces, and the middle plate 4 can be put in or taken out in a pulling manner along the corresponding bearing strip 211 and is supported by the corresponding bearing strip; the upper plate 3 can be horizontally drawn or pulled, and can be placed in or taken out from an upward opening between the top ends of the vertical plates 21 at two sides by adopting an up-and-down lifting mode.
Further, in order to increase the flowing speed, the flow channel groove of the upper layer column tube through hole 31 corresponds to the opening position of the flow channel groove of the corresponding middle layer column tube through hole 31, so as to reduce the liquid retention time and the pressure of the collection capacity of the gathering groove formed by the large hole section of the middle layer column tube through hole 31 and the column tube.
Correspondingly, in order to prevent the reverse placing, a fool-proof design can be added, as shown in fig. 3, a first stop part 212 is convexly arranged at the tail end of the supporting strip 211 on the vertical plate 21 on one side, and corresponding stop gaps 32 and 42 are arranged at the corresponding positions of the upper layer plate 3 and the middle layer plate 4; a second stopping portion 201 is convexly arranged at the corner where the vertical plate 21 and the bottom plate 20 are connected, and a stopping recess 53 is correspondingly arranged on the collecting tank 5.
Further, as shown in fig. 3 and 4, the collecting tank 5 is further provided with a pouring spout 51 and a handle 52, respectively, for facilitating pouring and holding of the liquid.
For convenient observation, the main body frame 2, the upper layer plate 3 and the middle layer plate can be made of transparent organic glass materials; the collecting tank can be made of stainless steel so as to prolong the service life.
The above description is only a preferred embodiment of the present invention, and should not be taken as limiting the invention, and any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (10)

1. Urine vanillic mandelic acid detects with special processing frame of anion exchange resin post, its characterized in that includes:
the main body frame is integrally in a model of 21274and consists of a bottom plate (20) and vertical plates (21) vertically connected with the left and right side ends of the bottom plate;
the collecting tank (5) is arranged at the lower part of the main body frame and can be put in or taken out in a drawing way from the front side inlet and outlet of the main body frame;
well plywood (4) and upper plate (3), be located the middle part and the top of main part frame respectively, be parallel to each other and leave the clearance each other, well plywood (4), a plurality of middle level column pipe through-holes (41), upper strata column pipe through-hole (31) of position one-to-one are seted up on upper plate (3), column pipe (1) of every anion exchange resin post are worn through upper strata column pipe through-hole (31) of upper plate (3), middle level column pipe through-hole (41) of middle plywood (4) in proper order, mouthpiece section (15) are towards collecting vat (5).
2. The special treatment rack for detecting urovanillylmandelic acid by using the anion exchange resin column according to claim 1, wherein the special treatment rack comprises: the collecting groove (5) is positioned above the bottom plate (20) and between the vertical plates (21) on the left side and the right side, and the middle layer plate (4) and the upper layer plate (3) are respectively positioned between the vertical plates (21) on the two sides and positioned in the middle and at the top of the collecting groove (5).
3. The special treatment rack for detecting urovanillylmandelic acid by using the anion exchange resin column according to claim 1, wherein the special treatment rack comprises: the minimum aperture of the upper-layer column tube through hole (31) is larger than the maximum outer diameter of the small-diameter section of the column tube and smaller than the minimum outer diameter of the large-diameter section.
4. The special treatment rack for urovanillylmandelic acid detection anion exchange resin column according to claim 1, characterized in that: the minimum aperture of the middle-layer column tube through hole (41) is larger than the maximum outer diameter of the nozzle section of the column tube and smaller than the minimum outer diameter of the small-diameter section.
5. The special treatment rack for urovanillylmandelic acid detection anion exchange resin column according to claim 1, characterized in that: the first transition section (12) of cup jointing and bearing spacing column pipe (1) is worn through by upper strata column pipe through-hole (31) of upper plate (3), wears through by middle level column pipe through-hole (41) of well layer board (4) and cup joints and bearing second transition section (14) of spacing column pipe (1).
6. The special treatment rack for detecting urovanillylmandelic acid by using the anion exchange resin column according to claim 1, wherein the special treatment rack comprises: the upper-layer column tube through hole (31) is set to be of a step hole structure, the upper-layer column tube through hole is a step hole with a large hole section below an upper small hole section, at least one runner groove is further formed in the inner wall surface of the small hole section, the upper end of the runner groove is communicated to the step surface between the large hole section and the small hole section, and the lower end of the runner groove is communicated to the orifice end surface below the small hole section.
7. The special treatment rack for urovanillylmandelic acid detection anion exchange resin column according to claim 1, characterized in that: the middle-layer column tube through hole (41) is set to be a step hole structure, and is a step hole with a large hole section at the upper part and a small hole section at the lower part, and the inner wall surface of the small hole section is also provided with at least one runner groove, the upper end of the runner groove is communicated to the step surface between the large hole section and the small hole section, and the lower end of the runner groove is communicated to the orifice end surface below the small hole section.
8. The special treatment rack for detecting urovanillylmandelic acid by using the anion exchange resin column according to claim 1, wherein the special treatment rack comprises: the opposite surfaces of the vertical plates (21) at the two sides are respectively provided with a bearing strip (211) for bearing the corresponding end of the upper plate (3) and the middle plate (4), and the middle plate and the upper plate can be put in or taken out along the corresponding bearing strips in a drawing mode.
9. The special treatment rack for urovanillylmandelic acid detection anion exchange resin column according to claim 1, characterized in that: a first stopping part (212) is convexly arranged at the tail end of the bearing strip on the vertical plate on one side, and corresponding stopping gaps are formed in the corresponding positions of the upper layer plate and the middle layer plate; a second stopping part (201) is convexly arranged at the connecting corner of the vertical plate and the bottom plate, and a stopping recess (53) is correspondingly arranged on the collecting groove.
10. The special treatment rack for urovanillylmandelic acid detection anion exchange resin column according to claim 1, characterized in that: the collecting tank is also provided with a pouring mouth part and a handle part respectively.
CN202222707523.2U 2022-10-14 2022-10-14 Special processing rack for detecting urovanillic mandelic acid by anion exchange resin column Active CN218306314U (en)

Priority Applications (1)

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CN202222707523.2U CN218306314U (en) 2022-10-14 2022-10-14 Special processing rack for detecting urovanillic mandelic acid by anion exchange resin column

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Application Number Priority Date Filing Date Title
CN202222707523.2U CN218306314U (en) 2022-10-14 2022-10-14 Special processing rack for detecting urovanillic mandelic acid by anion exchange resin column

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CN218306314U true CN218306314U (en) 2023-01-17

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