CN218305210U - Mouse fixer for local fixed-point irradiation - Google Patents

Abstract

The utility model relates to the field of mouse fixing devices, and discloses a mouse fixer for local fixed-point irradiation, which comprises a base, wherein the front end of the base is provided with a shade, the middle part of the base is provided with an elastic bandage, and both sides of the tail part of the base are provided with a slide rail and an adjusting knob; the slide rail is divided into two layers from top to bottom, and the upper strata is the sliding layer, and the lower floor is the fixed bed, adjust knob and sliding layer sliding connection, adjust knob and fixed bed joint. The scheme is used for solving the problem that the unanesthetized mouse cannot keep the same part always and fixedly exposed at the same position in the whole irradiation process.

Description

Mouse fixer for local fixed-point irradiation

Technical Field

The utility model relates to a mouse fixing device field, concretely relates to local fixed point is mouse fixer for irradiation.

Background

When cancer research is performed by irradiating a small animal, a local tumor experiment by irradiating the body of the mouse with X-rays is important, however, the experiment requires precise shielding of other parts of the body of the mouse so that X-rays are irradiated only to the tumor part.

In order to solve the above problems, the prior art provides a drawer-type tumor-bearing mouse local irradiation device, which shields other parts of the whole body by using a lead block, and adjusts the aperture size to allow the tumor part of the tumor-bearing mouse to pass through, thereby changing the irradiation area and achieving the purpose of only irradiating the tumor part. However, although the device can prevent the mouse from moving, in the study of tumor treatment drugs, in order to avoid the influence of anesthetic on the judgment of drug effectiveness, the mouse is not usually anesthetized, the mouse can still move some parts of the body, so that the tumor part moves, and the X-ray irradiates other positions of the mouse body, thereby influencing the efficiency and accuracy of the experiment.

Therefore, a fixer is urgently needed at present, which can be used together with a drawer type tumor-bearing mouse local irradiation device to fix all parts of the body of a mouse, prevent the tumor part from moving due to the movement of the mouse, and ensure that the unanesthetized mouse keeps the same part to be always fixed and exposed at the same position in the whole irradiation process.

SUMMERY OF THE UTILITY MODEL

The utility model aims at providing a local fixed point is mouse fixer for irradiation for solve above-mentioned problem.

The utility model provides a basic scheme does: a mouse fixer for local fixed-point irradiation comprises a base, wherein a shade is arranged at the front end of the base, an elastic binding band is arranged in the middle of the base, and sliding rails and adjusting knobs are arranged on two sides of the tail of the base; the slide rail is divided into two layers from top to bottom, and the upper strata is the sliding layer, and the lower floor is the fixed bed, adjust knob and sliding layer sliding connection, adjust knob and fixed bed joint.

The utility model discloses a theory of operation and advantage lie in:

the utility model relates to a mouse fixer is used in irradiation of local fixed point, the shade of base front end can be at the head and the hand of the fixed mouse of vertical direction, make the mouse can't lift head or hand, the elasticity bandage at middle part can bind up the chest abdomen of mouse, the adjust knob of afterbody can slide in the sliding layer of slide rail, to a slide allocation position, support the shank of mouse, when making the unable bigger degree of shank of mouse open, then push down adjust knob's top, with the adjust knob joint in the fixed bed of slide rail, accomplish the fixed to the shank. Compared with the prior art, the technical scheme has the advantages that the mask and the elastic bandage respectively fix the head and the body of the mouse, so that the mouse cannot move, the tumor position is prevented from moving, and the experiment efficiency and the experiment accuracy are improved; and the ingenious utilization power of this scheme mouse is self physiological structure, supports to a certain extent through adjust knob with the shank of mouse, makes the mouse can't fold two legs, and also can't continue when opening because skeleton and shank muscle restriction, fixes the adjust knob joint, and simultaneously, the edge of button cap will cause slight hindrance to the vertical direction removal of shank of mouse, makes the mouse can not move the shank of bullet under the state of not anaesthetizing.

Further, the shade includes cover head and cover tail, the cover tail is the open end, and the cover body enlarges from cover head to cover tail opening gradually. This scheme can reduce the pressure to the mouse neck when pushing down the mouse head and not letting it raise the head, avoids leading to the mouse to breathe unsmooth because of external reason and leads to the blood velocity of flow to accelerate, makes the experimental result more accurate.

Further, the hood head is provided with a breathing hole. This scheme can make the ventilation effect of shade better, prevents that mouse dyspnea from suffocating death even.

Furthermore, the breathing hole is a circular opening, and the diameter of the opening is 0.5cm. According to the scheme, the mouth of the mouse can be bound, so that the upper jaw and the lower jaw of the mouse cannot be opened and closed, and the mouse is prevented from biting the shade; therefore compare in the pressure through the shade itself and lead to the mouse can't be bitten by one's head, this scheme can further reduce the constraint intensity of shade to mouse head.

Further, the elastic bandage comprises a bandage and a reverse belt buckle, the reverse belt buckle is fixed on one side of the middle of the base, the bandage is fixed on the other side of the middle of the base, and the free end of the bandage is of an adhesion structure. This scheme can restrict the body of mouse, makes the unable turning over of mouse, more can't carry out action by a wide margin, though can slightly rub the action, nevertheless not only can not make the tumour position change, can prevent moreover that fixed dying leads to mouse chest and belly to receive the breathing of the too big influence mouse of pressure.

Further, the width of the binding band is 2cm. The scheme conforms to the body structure of the mouse and can cover the chest and the abdomen of the mouse, so that the body of the mouse is not convenient to exert force and the whole body of the mouse does not need to be completely bound; and compare in the whole health that covers the mouse completely, only cover the truck and can prevent that the height of mouse truck part and other parts from forming the difference in height, avoid influencing fixed effect.

Further, the length of the slide rail is 1/2 of the distance from the arc at the tail of the base to the elastic bandage. The scheme can ensure that the adjustable range of the adjusting knob can be close to the limit value of the stretching angle of the leg of the mouse, and the leg is continuously stretched to cause the muscle of the leg to be strained to generate pain, so that the mouse can be forced to avoid the urgent need of stretching the leg.

Further, the tail part of the base is an inward concave arc. This scheme can make mouse and base laminate more, and can save the material of base and the space that occupies.

Further, the base is acrylic material. Acrylic is also called organic glass, has strong light transmission, high hardness and strong safety, is not easy to break, and can not form sharp fragments even if broken.

Drawings

Fig. 1 is a top view of an embodiment of a mouse holder for localized spot irradiation according to the present invention;

fig. 2 is an enlarged cross-sectional view of the slide rail according to the first embodiment.

Detailed Description

The following is further detailed by way of specific embodiments:

the reference numbers in the drawings of the specification include: the mask comprises a base 1, a shade 2, an elastic bandage 3, a sliding rail 4, an adjusting knob 5, a sliding layer 41 and a fixing layer 42.

The first embodiment is as follows:

the base 1 is made of acrylic materials, the base 1 is of a plate-shaped structure, as shown in fig. 1, when the base is seen from top to bottom, the front end of the base 1 is bullet-shaped, the middle of the base 1 is rectangular, and the end part of the tail of the base 1 is an inward-concave circular arc similar to a dovetail shape. The front end of the base 1 is fixedly connected with a bullet-shaped shade 2, specifically, a notch is formed in the side wall of the front end of the base 1, the edge of the shade 2 is bonded in the notch through glue, the edge of the shade 2 is tightly attached to the side wall of the base 1 to form a bullet shape consistent with the shape of the front end of the base 1, the tail of the shade faces the tail opening of the base, and the caliber from the shade head to the shade tail opening is gradually enlarged; the mask head is provided with holes for air circulation, and the holes can be a plurality of tiny breathing holes, so that the ventilation effect of the mask 2 is better, and the mice are prevented from breathing difficultly and even die by suffocation; the opening may have a diameter of 0.5cm, for example, and the mouth of the mouse may be bound by the elasticity of the mask 2 so that the upper jaw and the lower jaw of the mouse cannot be opened and closed, and the mouse cannot bite the mask. When this scheme of adoption 2 of shade itself require to be lower to the constraint intensity of mouse head, need not push down the head of mouse completely through the pressure of 2 of shade itself, reduced the neck of mouse and compressed excessively and lead to stifled dead probability. An elastic bandage 3 is fixed in the middle of the base 1, and the elastic bandage 3 comprises a bandage and a reverse belt buckle; the bandage and the reverse belt buckle are respectively positioned on the inner edges of the left side and the right side of the middle part of the base 1, the fixing mode is similar to that of the shade 2, the inner edges of the two sides of the middle part of the base 1 are provided with grooves, the bandage is fixed in a glue bonding mode, the reverse belt buckle is fixed in the grooves in a clamping mode, the width of the bandage is 2cm, the bandage can cover the chest and the abdomen of a mouse, the body of the mouse is not convenient to exert force, and the whole body of the mouse does not need to be completely bound; compared with the method that the whole body of the mouse is completely covered, the method that the body is only covered on the trunk can prevent the height difference between the trunk part of the mouse and other parts from forming, and the fixing effect is prevented from being influenced; in this embodiment, base 1's left side inward flange is reverse belt buckle, and the right side inward flange is the bandage, and the strapping is pasted to the concrete optional magic of bandage, and the bonding region of the free end upside of bandage for having tiny hook body passes reverse belt buckle and just in time bonds at the upper surface of bandage when returning again, and reverse belt buckle is held to the left hand, and the right hand is held the bandage and is tied up, accords with most people and is used to the hand condition for the right hand, is convenient for operate. As shown in the attached figure 2, the two sides of the tail part of the base 1 are provided with the mutually symmetrical slide rails 4, the slide rails 4 are arranged along the length direction of the base 1, compared with the arrangement along the width direction of the base 1, the scheme ensures that a mouse cannot fold inwards by two legs to exert force to cause the adjusting knob 5 to move; the length of slide rail 4 is 1/2 of the arc of base 1 afterbody to 3 distances of elasticity bandage, two slide rails 4 divide into three regions with the width direction equidistance of base 1 afterbody, slide rail 4 is divided into two-layer from last to down, the upper strata is sliding layer 41, the lower floor is fixed bed 42, the afterbody of base 1 still is equipped with the adjust knob 5 who passes slide rail 4, adjust knob 5 and sliding layer 41 sliding connection, at first in sliding layer 41, push down adjust knob 5 when needs are fixed and connect its joint to fixed bed 42 in, screw out adjust knob 5 when needs remove adjust knob 5's position, thereby slide in sliding layer 41.

The prior art has the technical prejudice that in the experiment of irradiating local tumor by X-ray, when the shielding plate is used for shielding other parts of the mouse body, the mouse can not move up, down, left and right, and the purpose of fixing the mouse is achieved, so that the tumor part only needs to be kept fixed, and the complete fixation of the mouse can not be realized. In the case, although the mouse cannot move, the mouse can still perform actions such as curling and turning over, so that the posture of the mouse is changed to a certain extent, a tumor part is partially shielded, and the experiment efficiency and the experiment accuracy are affected. Even if some people also pay attention to the problem of tumor movement, the mice are usually fixed by using a conventional fixing structure, and the problem that the breathing difficulty and the influence on the experimental result exist when the mice are fixed too fast in an originally closed scene cannot be considered. And this scheme has overcome above-mentioned technical bias, fix the head and the chest abdomen of mouse through shade 2 and elasticity bandage 3, both reached fixed purpose, can not make the mouse breathe again and receive the influence, and simultaneously, ingenious utilization mouse self physiological structure, support the shank of mouse to a certain extent through adjust knob 5, make the mouse can't fold the both legs, and when also can't continue to open because skeleton and shank muscle restriction, fix adjust knob 5 joint in slide rail 4, need not tie up the shank of mouse and tie up and also can make its shank fixed, avoid influencing the blood flow of mouse, the authenticity and the accuracy of experiment have been improved.

The above description is only for the embodiment of the present invention, and the common general knowledge of the known specific structures and characteristics in the schemes is not described herein too much, so that those skilled in the art can know all the common technical knowledge in the technical field of the present invention before the application date or the priority date, can know all the prior art in this field, and have the capability of applying the conventional experimental means before this date, and those skilled in the art can complete and implement the schemes in combination with their own capability, and some typical known structures or known methods should not become obstacles for those skilled in the art to implement the present application. It should be noted that, for those skilled in the art, without departing from the structure of the present invention, several modifications and improvements can be made, which should also be regarded as the protection scope of the present invention, and these will not affect the effect of the implementation of the present invention and the practicability of the patent. The scope of the claims of the present application shall be determined by the contents of the claims, and the description of the embodiments and the like in the specification shall be used to explain the contents of the claims.

Claims (9)

1. A mouse fixer for local fixed-point irradiation is characterized by comprising a base, wherein the front end of the base is provided with a bullet-shaped mask, the mask is tensioned and fixed on the side wall of the base, the middle part of the base is provided with an elastic bandage, and two sides of the tail part of the base are provided with a slide rail and an adjusting knob; the slide rail is divided into two layers from top to bottom, and the upper strata is the sliding layer, and the lower floor is the fixed bed, adjust knob and sliding layer sliding connection, adjust knob can dismantle with the fixed bed and be connected.

2. The mouse holder for local fixed-point irradiation according to claim 1, wherein the mask comprises a head and a tail, the tail is provided with an opening facing the tail of the base, and the aperture of the mask gradually increases from the head to the tail.

3. The mouse holder for localized spot irradiation of claim 2, wherein the mask head has a breathing hole.

4. The mouse holder for local fixed-point irradiation according to claim 3, wherein the breathing hole is a circular opening with a diameter of 0.5cm.

5. The mouse holder for localized spot irradiation of claim 1, wherein the elastic strap comprises a strap and a reverse buckle, the reverse buckle is fixed on one side of the middle portion of the base, the strap is fixed on the other side of the middle portion of the base, and the free end of the strap is in an adhesive structure.

6. The mouse holder for localized spot irradiation of claim 5, wherein the width of the band is 2cm.

7. The mouse fixer for local fixed-point irradiation according to claim 1, wherein the length of the slide rail is 1/2 of the distance from the arc of the tail of the base to the elastic bandage.

8. The mouse holder for localized spot irradiation of claim 1, wherein the tail of the base is an inwardly concave arc.

9. The mouse holder for local fixed-point irradiation according to claim 1, wherein the base is made of acrylic material.

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