CN218249884U - Production device for coating culture bottle - Google Patents
Production device for coating culture bottle Download PDFInfo
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- CN218249884U CN218249884U CN202222179503.2U CN202222179503U CN218249884U CN 218249884 U CN218249884 U CN 218249884U CN 202222179503 U CN202222179503 U CN 202222179503U CN 218249884 U CN218249884 U CN 218249884U
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Abstract
The utility model discloses a production device for a coated culture bottle, which comprises a base, a mounting bracket, a mixing motor, a liquid separator and a turnover motor; the base is provided with a linear guide rail; the mounting bracket is movably arranged on the base along the linear guide rail; the blending motor is arranged on the base and used for driving the mounting bracket to reciprocate along the linear guide rail; the liquid distributor is fixed on the overturning bracket, and the overturning bracket can be rotatably arranged on the mounting bracket; the overturning motor is fixed on the mounting bracket and used for driving the overturning bracket to rotate. Among the above-mentioned peridium blake bottle apparatus for producing, mixing motor and upset motor can drive the knockout respectively and rock and overturn, realize utilizing the knockout supplementary peridium blake bottle production of carrying on, compare in the mode of artifical manual peridium blake bottle, do benefit to and improve production efficiency.
Description
Technical Field
The invention relates to the technical field of cell culture, in particular to a production device of a coated culture bottle.
Background
The coating culture flask is one of the most common treatment modes in cell culture, and can excellently promote the growth of cells. In the prior art, the coated culture bottles are usually coated in a manual mode, and only small batches of coated culture bottles can be coated one by one, so that the efficiency is low.
In order to improve work efficiency, can adopt the knockout to assist and carry out the production of peridium blake bottle, the knockout can equally divide into many with liquid, is convenient for to a plurality of blake bottle input or output liquid simultaneously, realizes peridium a plurality of blake bottles simultaneously. However, the liquid inlet and the liquid outlet of the liquid separator are respectively positioned at two sides, the liquid inlet is positioned below the liquid separating device before liquid separation, and the liquid outlet is positioned above the liquid separating device. The existing liquid separator only has an equipartition function and cannot realize shaking and overturning.
Therefore, how to make the knockout realize rocking and upset to utilize the knockout to assist and carry out the production of peridium blake bottle, improve production efficiency, the problem that the skilled person in the art needs to solve urgently.
SUMMERY OF THE UTILITY MODEL
In view of this, the utility model provides a peridium blake bottle apparatus for producing, its mixing motor and upset motor are used for driving the knockout respectively and rock and overturn, can realize utilizing the knockout to assist and carry out the production of peridium blake bottle, compare in artifical manual mode of peridium blake bottle one by one, are showing and are improving production efficiency.
In order to achieve the above object, the utility model provides a following technical scheme:
a coated culture flask production device, comprising:
a base; the base is provided with a linear guide rail;
the mounting bracket is movably arranged on the base along the linear guide rail;
the blending motor is arranged on the base and used for driving the mounting bracket to reciprocate along the linear guide rail;
the liquid distributor is fixed on the overturning bracket, and the overturning bracket can be rotatably arranged on the mounting bracket;
the overturning motor is fixed on the mounting bracket and used for driving the overturning bracket to rotate.
Preferably, in the above production apparatus for coated culture bottles, the turning support is fixed with a bottle holder for mounting the culture bottle; each liquid outlet of the liquid separator is respectively communicated with different culture bottles; the bottle rack is positioned on one side of the liquid outlet of the liquid distributor, which deviates from the liquid inlet of the liquid distributor.
Preferably, the apparatus for producing a coated culture flask further comprises:
the liquid bags are multiple and are respectively communicated with the liquid inlet of the liquid separator through a guide pipe;
the peristaltic pump is arranged in the conduit between the liquid bag and the liquid distributor and is used for driving liquid to flow.
Preferably, in the above production apparatus, the base is provided with a liquid hanging rack, and the liquid bag is hung on the liquid hanging rack.
Preferably, in the above apparatus for producing coated culture bottles, the liquid hanging rack comprises:
the bracket is fixed on the base;
and the hook is arranged on the support through a weighing sensor.
Preferably, in the above coated culture flask production apparatus, the liquid bags include at least one coating liquid sample bag, at least one washing solution bag, at least one preserving solution bag, and at least one waste liquid bag; the coating liquid sample bag, the cleaning solution bag and the preservation solution bag are respectively communicated with a first port of the peristaltic pump through a first bubble sensor, and the waste liquid bag is directly communicated with the first port through a conduit; and a second port of the peristaltic pump is communicated with the liquid inlet of the liquid distributor through a second bubble sensor.
Preferably, in the above apparatus for producing a coated culture flask, the conduit for communicating the openings of the liquid bags is provided with an electromagnetic pinch valve for controlling the opening and closing of the openings of the liquid bags.
Preferably, the production device of the coated culture bottle further comprises an operation panel arranged on the base, wherein the operation panel is at least provided with a microcomputer and used for controlling the blending motor, the overturning motor, the peristaltic pump and the electromagnetic pinch valve; the first bubble sensor and the second bubble sensor are respectively in signal connection with the microcomputer.
Preferably, in the above-described apparatus for producing a coated culture flask, the peristaltic pump, the first bubble sensor, the second bubble sensor, and the electromagnetic pinch valve are respectively attached to the operation panel.
Preferably, in the above coated culture bottle production apparatus, opto-couplers are respectively disposed between the bodies of the turnover motor and the mixing motor and the transmission shaft, and are used for detecting the operation state of the transmission shaft and correcting the reset point; the optical coupler is connected with the microcomputer.
The utility model provides a production device for a coated culture bottle, which comprises a base, a mounting bracket, a mixing motor, a liquid separator and a turnover motor; the base is provided with a linear guide rail; the mounting bracket can be movably arranged on the base along the linear guide rail; the blending motor is arranged on the base and used for driving the mounting bracket to reciprocate along the linear guide rail; the liquid separator is fixed on the turning bracket, and the turning bracket can be rotatably arranged on the mounting bracket; the overturning motor is fixed on the mounting bracket and used for driving the overturning bracket to rotate.
The utility model provides an among the peridium blake bottle apparatus for producing, mixing motor and upset motor can drive the knockout respectively and rock and overturn, realize utilizing the knockout to assist and carry out the production of peridium blake bottle, compare in the mode of artifical manual peridium blake bottle, do benefit to improvement production efficiency.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
FIG. 1 is a schematic structural view of a coated culture flask production device according to an embodiment of the present invention;
wherein, in fig. 1:
a hanging rack 101; a fluid bag 102; a solenoid pinch valve 103; a first bubble sensor 104; a peristaltic pump 105; an operation panel 106; a microcomputer 107; a roll-over motor 108; a bottle holder 109; a culture flask 110; the dispenser fixing lever 111; a liquid separator 112; a blending motor 113; a linear guide rail 114; a base 115.
Detailed Description
The embodiment of the utility model discloses peridium blake bottle apparatus for producing, its mixing motor and upset motor are used for driving the knockout respectively and rock and overturn, can realize utilizing the knockout to assist and carry out the production of peridium blake bottle, compare in artifical manual mode of peridium blake bottle one by one, are showing and are improving production efficiency.
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Referring to fig. 1, an embodiment of the present invention provides a device for producing a coated culture flask, including a base 115, a mounting bracket, a blending motor 113, a dispenser 112, and a turnover motor 108; the base 115 is provided with a linear guide rail 114; the mounting bracket is movably provided to the base 115 along the linear guide 114; the blending motor 113 is installed on the base 115 and used for driving the installation support to reciprocate along the linear guide rail 114; the liquid separator 112 is fixed on a turning bracket which can be rotatably arranged on the mounting bracket; the turning motor 108 is fixed on the mounting bracket, and the turning motor 108 is used for driving the turning bracket to rotate.
The embodiment of the utility model provides an among the peridium blake bottle apparatus for producing, mixing motor 113 and upset motor 108 are used for driving knockout 112 respectively and rock and overturn, make the knockout equally divide into many with liquid, are convenient for carry the required liquid of each step in the production of equivalent peridium respectively to a plurality of blake bottles 110 simultaneously, realize peridium to a plurality of blake bottles 110 simultaneously, compare in the manual mode of peridium blake bottle one by one of manual work, show improvement production efficiency, can also practice thrift the cost of labor.
In the production device of the coated culture bottle, a bottle rack 109 is fixed on the overturning bracket, and the bottle rack 109 is used for installing a culture bottle 110; the liquid separator 112 has a plurality of liquid outlets, each for outputting a different divided liquid; each liquid outlet of the liquid separator 112 is used for being respectively communicated with different culture bottles 110; the bottle holder 109 is located at a side of the liquid outlet of the liquid separator 112 facing away from the liquid inlet of the liquid separator 112, so that the liquid can automatically flow into different culture bottles 110 under the action of gravity after the liquid is equally divided by the liquid separator 112 in an overturning way.
Specifically, the dispenser 112 is fixed to the turning bracket by a dispenser fixing rod 111.
Preferably, the above-mentioned apparatus for producing a coated culture flask further comprises:
a plurality of liquid bags 102, wherein each liquid bag 102 is communicated with the liquid inlet of the liquid separator 112 through a conduit;
a peristaltic pump 105, the peristaltic pump 105 being disposed in the conduit between the fluid bag 102 and the dispenser 112 for driving the flow of fluid.
The peridium blake bottle apparatus for producing that this embodiment provided has set up liquid bag and peristaltic pump, need not artifical manual adding liquid, is convenient for carry different liquid to the peridium blake bottle as required, can further improve production efficiency.
In the above-described apparatus for producing a coated culture flask, the liquid bag 102 is mounted on the liquid hanging rack 101, and the liquid bag 102 is hung on the liquid hanging rack 101, in order to assemble the liquid bag 102.
The liquid hanging rack 101 comprises a support and a hook, and the support is fixed on the base 115; the hook is arranged on the bracket through the weighing sensor. The weight of remaining liquid in the liquid bag 102 can be monitored to weighing sensor, and the user of being convenient for in time changes new liquid bag 102 when remaining liquid volume is not enough in liquid bag 102, ensures that the peridium blake bottle lasts production, improves production efficiency.
Specifically, the liquid bags 102 in the coated culture flask production device include at least one coating liquid sample bag, at least one cleaning solution bag, at least one preservation solution bag, and at least one waste liquid bag; the coating liquid sample bag, the cleaning solution bag and the preservation solution bag are respectively communicated with a first port of a peristaltic pump 105 through a first bubble sensor 104; the waste liquid bag is directly communicated with the first port through a conduit, so that a peristaltic pump can conveniently pump redundant coating liquid or cleaning solution in the culture medium 110 to the waste liquid bag according to the requirement of the production step; a second port of the peristaltic pump 105 communicates with an inlet port of the liquid separator 112 via a second bubble sensor.
In the above-mentioned apparatus for producing a coated culture flask, electromagnetic pinch valves 103 are provided on the conduits for communicating the openings of the liquid bags 102, respectively, for controlling the opening and closing of the openings of the liquid bags 102.
The production device of the coated culture bottle can be produced by adopting the following operation steps:
1) Conveying coating liquid: firstly, opening an electromagnetic pinch valve 103 of a conduit at an opening of a coating liquid sample bag, starting a peristaltic pump 105 to convey a proper amount of coating liquid to a liquid separator 112, and closing the electromagnetic pinch valve 103 and the peristaltic pump 105; the liquid is evenly distributed by the liquid distributor 112 and then is conveyed to each culture bottle 110, the culture bottles 110 are shaken by the mixing motor 113, and then the culture bottles 110 are turned by the turning motor 108, so that redundant coating liquid in the culture bottles 110 enters the liquid distributor 112 under the action of gravity; then the peristaltic pump 105 is turned on to pump the coating liquid into the waste liquid bag;
2) Cleaning the culture flask 110: firstly, opening an electromagnetic pinch valve 103 of a conduit at the opening of the cleaning solution bag, starting a peristaltic pump 105 to convey a proper amount of cleaning solution to a liquid distributor 112, and closing the electromagnetic pinch valve 103 and the peristaltic pump 105; uniformly distributing liquid in the liquid distributor 112, conveying the liquid to each culture bottle 110, shaking the culture bottles 110 by using a uniformly mixing motor 113, and then overturning the culture bottles 110 by using an overturning motor 108 to ensure that the cleaning solution in the culture bottles 110 enters the liquid distributor 112 under the action of gravity; then the peristaltic pump 105 is turned on to pump the cleaning solution into the waste liquid bag;
3) Conveying the preservation solution: firstly, opening an electromagnetic pinch valve 103 of a catheter at an opening of a preservation solution bag, starting a peristaltic pump 105 to convey a proper amount of preservation solution to a liquid separator 112, and closing the electromagnetic pinch valve 103 and the peristaltic pump 105; the liquid is equally divided by the liquid divider 112 and then is conveyed to each culture bottle 110;
4) Packaging and storing: the pipeline connected with the liquid distributor 112 above the bottle cap of the culture bottle 110 is sealed and separated by a heat sealing instrument, and then the culture bottle 110 is taken down and kept flat in an environment at 4 ℃ for standby.
In order to improve the automation degree, the production device of the coated culture bottle also comprises an operation panel 106 arranged on a base 115, and the operation panel 106 is at least provided with a microcomputer 107 and used for controlling a blending motor 113, a turnover motor 108, a peristaltic pump 105 and an electromagnetic pinch valve 103; the first bubble sensor and the second bubble sensor are respectively connected with the microcomputer 107 through signals.
The peristaltic pump 105, the first bubble sensor 104, the second bubble sensor, and the solenoid pinch valve 103 are respectively mounted to an operation panel 106. Preferably, optocouplers are respectively arranged between the bodies of the turnover motor 108 and the blending motor 113 and the transmission shaft and are used for detecting the running state of the transmission shaft and correcting a reset point; the opto-coupler is connected to a microcomputer 107.
The microcomputer 107 is connected with a touch display screen, so that an operator can conveniently operate a program and display the operation and the process parameters of each unit through the touch display screen, wherein the process parameters comprise the volume and the path of sample inlet and outlet, the centrifugal speed, the overturning speed and the time of the overturning motor 108, the horizontal mixing speed and the horizontal mixing strength of the mixing motor 113 and the like.
The production device for the coating culture bottle has the advantages of simple structure, convenience in production and manufacture, high automation degree and convenience in large-scale production.
The embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (10)
1. A production device for a coated culture bottle is characterized by comprising:
a base; the base is provided with a linear guide rail;
the mounting bracket is movably arranged on the base along the linear guide rail;
the blending motor is arranged on the base and used for driving the mounting bracket to reciprocate along the linear guide rail;
the liquid distributor is fixed on the overturning bracket, and the overturning bracket can be rotatably arranged on the mounting bracket;
and the overturning motor is fixed on the mounting bracket and used for driving the overturning bracket to rotate.
2. The apparatus for producing coated culture bottles of claim 1, wherein the turning frame is fixed with a bottle holder for mounting the culture bottles; each liquid outlet of the liquid separator is respectively communicated with different culture bottles; the bottle rack is positioned on one side of the liquid outlet of the liquid distributor, which deviates from the liquid inlet of the liquid distributor.
3. The coated culture flask production device as recited in claim 1, further comprising:
the liquid bags are multiple and are respectively communicated with the liquid inlet of the liquid separator through a guide pipe;
the peristaltic pump is arranged in the conduit between the liquid bag and the liquid distributor and is used for driving liquid to flow.
4. The apparatus for producing coated culture bottles of claim 3, wherein the base is provided with a liquid hanging rack, and the liquid bag is hung on the liquid hanging rack.
5. The coated culture bottle production device as claimed in claim 4, wherein the rack for hanging liquid comprises:
the bracket is fixed on the base;
and the hook is arranged on the support through a weighing sensor.
6. The coated culture bottle production device as claimed in claim 3, wherein the liquid bags include at least one coating liquid sample bag, at least one washing solution bag, at least one preserving solution bag, at least one waste liquid bag; the coating liquid sample bag, the cleaning solution bag and the preservation solution bag are respectively communicated with a first port of the peristaltic pump through a first bubble sensor, and the waste liquid bag is directly communicated with the first port through a conduit; and a second port of the peristaltic pump is communicated with the liquid inlet of the liquid distributor through a second bubble sensor.
7. The apparatus for producing coated culture flasks according to claim 6, wherein the conduits for communicating the openings of the respective liquid bags are provided with electromagnetic pinch valves for controlling the opening and closing of the openings of the liquid bags.
8. The coated culture bottle production device as claimed in claim 7, further comprising an operation panel mounted on the base, wherein the operation panel is at least provided with a microcomputer for controlling the blending motor, the turnover motor, the peristaltic pump and the electromagnetic pinch valve; the first bubble sensor and the second bubble sensor are respectively in signal connection with the microcomputer.
9. The coated culture bottle production device according to claim 8, wherein the peristaltic pump, the first bubble sensor, the second bubble sensor and the solenoid pinch valve are respectively mounted to the operation panel.
10. The production device of the coated culture bottle as claimed in claim 8, wherein optical couplers are respectively arranged between the bodies of the turnover motor and the blending motor and the transmission shaft, and are used for detecting the running state of the transmission shaft and correcting a reset point; the optical coupler is connected with the microcomputer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222179503.2U CN218249884U (en) | 2022-08-18 | 2022-08-18 | Production device for coating culture bottle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222179503.2U CN218249884U (en) | 2022-08-18 | 2022-08-18 | Production device for coating culture bottle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN218249884U true CN218249884U (en) | 2023-01-10 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202222179503.2U Active CN218249884U (en) | 2022-08-18 | 2022-08-18 | Production device for coating culture bottle |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN218249884U (en) |
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2022
- 2022-08-18 CN CN202222179503.2U patent/CN218249884U/en active Active
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