CN218157177U - Sample slide cleaning box and slide pushing and dyeing machine - Google Patents
Sample slide cleaning box and slide pushing and dyeing machine Download PDFInfo
- Publication number
- CN218157177U CN218157177U CN202222053624.2U CN202222053624U CN218157177U CN 218157177 U CN218157177 U CN 218157177U CN 202222053624 U CN202222053624 U CN 202222053624U CN 218157177 U CN218157177 U CN 218157177U
- Authority
- CN
- China
- Prior art keywords
- cleaning
- sample slide
- cavity
- side wall
- slide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000004140 cleaning Methods 0.000 title claims abstract description 214
- 238000004043 dyeing Methods 0.000 title claims abstract description 22
- 239000007788 liquid Substances 0.000 claims abstract description 89
- 238000005406 washing Methods 0.000 claims abstract description 53
- 238000002347 injection Methods 0.000 claims abstract description 41
- 239000007924 injection Substances 0.000 claims abstract description 41
- 239000008280 blood Substances 0.000 claims abstract description 31
- 210000004369 blood Anatomy 0.000 claims abstract description 31
- 238000000034 method Methods 0.000 claims abstract description 4
- 238000010186 staining Methods 0.000 claims description 37
- 239000000243 solution Substances 0.000 claims description 31
- 238000003780 insertion Methods 0.000 claims description 23
- 230000037431 insertion Effects 0.000 claims description 23
- 239000002699 waste material Substances 0.000 claims description 2
- 230000037452 priming Effects 0.000 claims 5
- 238000004088 simulation Methods 0.000 abstract description 4
- 238000002791 soaking Methods 0.000 abstract description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 11
- 238000005086 pumping Methods 0.000 description 9
- 239000013049 sediment Substances 0.000 description 8
- 238000009825 accumulation Methods 0.000 description 4
- 238000007639 printing Methods 0.000 description 4
- 239000002893 slag Substances 0.000 description 4
- 238000013461 design Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 230000003670 easy-to-clean Effects 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000003855 cell nucleus Anatomy 0.000 description 1
- 210000000805 cytoplasm Anatomy 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000009595 pap smear Methods 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/34—Purifying; Cleaning
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B13/00—Accessories or details of general applicability for machines or apparatus for cleaning
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
- B08B3/02—Cleaning by the force of jets or sprays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
- B08B3/04—Cleaning involving contact with liquid
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The utility model provides a sample slide washs box and pushes away dyeing machine, sample slide washs box is including wasing the cavity and wasing the liquid injection passageway, it is used for holding washing liquid and sample slide to wash the cavity, wash the liquid injection passageway be used for to wash the cavity and pour into the washing liquid into, wherein, it is used for holding vertical male sample slide to wash the cavity, just the sample slide scribbles the one side orientation of blood film wash the liquid injection passageway, it is in to wash the liquid injection passageway setting wash on the first side wall of cavity for pour into the washing liquid into to wash the cavity and wash the sample slide. The utility model discloses a sample slide washs box washes through setting up the front that washs notes liquid channel simulation tap washing sample slide, openly washes and to the back of sample slide through the cleaning method of soaking back drawing liquid through adopting the sample slide, makes the sample slide wash cleaner, and is convenient.
Description
Technical Field
The utility model relates to an in vitro diagnosis technical field, more specifically say, relate to a sample slide washs box and pushes away dyeing machine.
Background
Currently, in a pathology department of a hospital, various research institutes or a biomedical company, exfoliated cells (such as cervical screening) or biological tissues (such as local tissues of animals or human bodies) or blood need to be subjected to slice staining, and doctors can accurately diagnose various diseases by observing variation conditions of cell nuclei and cytoplasm in the tissues through a microscope, for example, whether inflammation, benign tumor or malignant tumor exists is judged.
In the prior art, the sample slide after slide making and dyeing needs to be cleaned, otherwise, staining residues can be attached to the blood film of the sample slide, so that the slide making work of a doctor or a slide making analyzer is influenced, and the work quality and the work efficiency are reduced.
At present, most staining and cleaning methods adopt the mode of injecting cleaning liquid to soak and clean or the mode of spitting the liquid mouth and washing towards the side edge of the sample slide, but do not directly act on the front side of the sample slide to wash. The back of the sample slide is smooth and has no blood film, the back of the sample slide is not easy to adhere to the staining residues, the back staining residues are easy to clean by adopting the 2 modes, the front of the sample slide is coated with the blood film, the staining residues are easy to adhere to the blood film, and the front staining residues are not easy to clean by adopting the 2 modes.
SUMMERY OF THE UTILITY MODEL
In view of this, the present application provides a sample slide cleaning box and a slide pushing and dyeing machine, which are used to solve at least one of the above technical problems, and provide a sample slide cleaning box and a slide pushing and dyeing machine with simple structure and good cleaning effect.
The utility model discloses a sample slide cleaning box, including wash the cavity and with wash the washing liquid injection passageway that the inside of cavity is linked together, wherein, wash the cavity and be used for holding vertical male sample slide, just the sample slide scribbles the one side orientation of blood film wash the liquid injection passageway, it sets up to wash the liquid injection passageway wash on the first side wall of cavity for pour into the washing liquid into to wash in the cavity and wash the sample slide.
In a preferred embodiment, the cleaning chamber is a rectangular parallelepiped structure surrounded by circumferential side walls and a bottom wall.
In a preferred embodiment, a guide portion is disposed in the cleaning chamber, and the guide portion includes a guide insertion opening through which a sample slide passes to guide and stabilize the sample slide received in the cleaning chamber.
In a preferred embodiment, the bottom of the cleaning cavity is provided with a negative pressure liquid pumping channel for discharging the waste liquid after cleaning.
In a preferred embodiment, an overflow cavity is disposed on a second side wall opposite to a first side wall where the cleaning liquid injection channel is located, the overflow cavity is disposed on one side of the second side wall away from the first side wall, an overflow port is disposed on the second side wall, so that redundant liquid in the cleaning cavity overflows to the overflow cavity through the overflow port, and a natural overflow port is disposed at the bottom of the overflow cavity.
In a preferred embodiment, the guiding parts are respectively arranged at one side of a third side wall and a fourth side wall adjacent to the first side wall of the cleaning cavity, and the guiding parts are respectively connected with at least one of the first side wall, the second side wall, the third side wall and the fourth side wall, wherein the guiding part at each side comprises a first guiding part and a second guiding part, and the first guiding part comprises a first inserting sheet opening for guiding; the second guide part comprises a second inserting opening for guiding; the first inserting piece opening and the second inserting piece opening are coaxially arranged.
In a preferred embodiment, the first guide portion and the second guide portion are coaxially arranged in a vertical direction, and the first guide portion and the second guide portion are discontinuously arranged.
In a preferred embodiment, the first guide portion is connected to the first side wall and the second side wall, respectively, and the second guide portion is connected to the first side wall and the second side wall, respectively.
In a preferred embodiment, a bottom bearing portion for supporting the sample slide is further arranged in the cleaning cavity, the bottom bearing portion comprises a third insert opening for guiding, the third insert opening is coaxially arranged with the second insert opening and the first insert opening, the opening diameter of the first insert opening is smaller than that of the second insert opening, and the opening diameter of the third insert opening is smaller than that of the second insert opening.
In a preferred embodiment, the injection direction of the cleaning liquid injection channel is inclined towards the bottom of the cleaning cavity, and the included angle between the injection direction of the cleaning liquid and the central line of the sample slide accommodated in the cleaning cavity is in the range of 30-45 °.
In a preferred embodiment, the cleaning liquid injection channel comprises a first cleaning liquid injection channel and a second cleaning liquid injection channel, and the first cleaning liquid injection channel and the second cleaning liquid injection channel are arranged side by side at the same horizontal height.
In a preferred embodiment, the distances between the circumferential side wall and the bottom wall of the washing chamber and the sample slide accommodated in the washing chamber are both greater than 0.
In a preferred embodiment, the distance between the first side wall and the sample slide accommodated in the cleaning cavity is a first distance, and the distance between the second side wall opposite to the first side wall where the cleaning liquid injection channel is located and the sample slide accommodated in the cleaning cavity is a second distance, wherein a ratio between the first distance and the second distance is in a range of 1: 1.5-1: 3.
in a preferred embodiment, the cleaning cavity further includes vents, the vents are respectively disposed at two sides of the cleaning cavity where the guide portion is located, and are respectively surrounded by a third sidewall or a fourth sidewall of the main body of the guide portion adjacent to the first sidewall of the cleaning cavity, and are communicated with the inside of the cleaning cavity.
In a preferred embodiment, a cleaning solution flow guide surface is further disposed in the cleaning cavity, the cleaning solution flow guide surface is disposed at the inner side of the bottom of the cleaning cavity, the cleaning solution flow guide surface faces to the opposite side of the cleaning liquid injection channel and is inclined towards the bottom of the cleaning cavity, and the negative pressure liquid pumping channel is disposed at the lowest point of the cleaning solution flow guide surface.
In a preferred embodiment, the cleaning liquid guiding surface is a curved surface or a flat surface.
Based on the sample slide washs box that above-mentioned provided, the utility model also provides a push away dyeing machine, include:
the smear module is used for preparing a blood film smear;
the staining module is used for staining the blood film smear;
the device also comprises at least one sample slide cleaning box used for cleaning a blood film smear.
In one embodiment, the dyeing module further comprises a washing tank, a dyeing tank and a fixed tank;
the sample slide cleaning box is detachably placed in the cleaning groove;
the cleaning tank is arranged in parallel with the dye solution tank and the fixed solution tank.
Compared with the prior art, the utility model discloses a sample slide cleaning box washs liquid filling channel simulation tap through setting up the front that washs the sample slide, adopts and openly washes and the sample slide back soaks the mode that washs and combine together to the sample slide, makes the sample slide wash cleaner, and is convenient.
The technical features mentioned above can be combined in various technically feasible ways to produce new embodiments, as long as the objects of the invention are achieved.
Drawings
Fig. 1 is a left side view of a sample slide washing cassette provided by an embodiment of the present invention;
fig. 2 is a perspective view of a specimen slide washing cassette provided in an embodiment of the present invention;
FIG. 3 is a cross-sectional view of a sample slide washing cassette provided in an embodiment of the present invention;
FIG. 4 is another cross-sectional view of a sample slide washing cassette provided in an embodiment of the present invention;
FIG. 5 is another cross-sectional view of a sample slide washing cassette provided in an embodiment of the present invention;
fig. 6 is a perspective view of a specimen slide washing cassette provided in accordance with an embodiment of the present invention;
FIG. 7 is a schematic diagram of an application of a specimen slide cleaning cassette according to an embodiment of the present invention;
fig. 8 is a structural diagram of another application of the specimen slide cleaning box according to the embodiment of the present invention.
Wherein the reference numerals are:
1. cleaning the liquid injection channel; 2. a negative pressure liquid pumping channel; 3. a natural overflow port; 4. an overflow cavity; 5. cleaning the cavity; 51. cleaning the cavity opening; 511. a first side wall; 52. an overflow port; 53. a vent; 531. a third side wall; 54. flushing the area; 55. a dye residue accumulation area; 6. a guide portion; 61. a first guide portion; 611. a first card slot; 62. a second guide portion; 621. a second card slot; 63. a bottom carrier portion; 631. a third wafer insertion opening; 7. a cleaning fluid diversion surface; 8. a cleaning liquid impact point; 10. a sample slide; 11. a small area.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
It should be noted that unless otherwise defined, technical terms or scientific terms used herein should have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terms "first," "second," and the like, do not denote any order, quantity, or importance, but rather are used to distinguish one element from another. The word "comprising" or "comprises", and the like, means that the element or item listed before the word covers the element or item listed after the word and its equivalents, but does not exclude other elements or items. In the description of the present invention, the terms "upper", "lower", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for convenience of description, rather than indicating or implying that the device or element being referred to must have a specific orientation, be constructed and operated in a specific orientation, and when the absolute position of the object being described is changed, the relative positional relationship may also be changed accordingly, and thus, should not be construed as limiting the present invention.
The technology not mentioned in the utility model can be realized through the prior art.
First, some terms related to the embodiments of the present invention are explained to facilitate understanding by those skilled in the art.
Front side of sample slide: the side of the sample slide coated with the blood film.
Back side of sample slide: the side of the sample slide not coated with the blood film, i.e. the side opposite to the front side of the sample slide.
As shown in fig. 1-6, the embodiment of the utility model provides a sample slide washs box, including wasing cavity 5 and wasing notes liquid passageway 1, wash cavity 5 and be used for holding washing liquid and sample slide 10, sample slide 10 is kept away from the base of printing the end and is washed the vertical inserting of direction bottom cavity 5 with the orientation and place in wasing cavity 5, the front orientation of sample slide washs notes liquid passageway 1 one side, it is used for pouring into the washing liquid and wash sample slide 10 into to wasing cavity 5 to wash notes liquid passageway 1, wherein wash notes liquid passageway 1 and set up on the first lateral wall 511 that washs cavity 5, and with wash the inside intercommunication of cavity 5.
After investigation and analysis, in actual work, when medical staff manually clean a sample slide, the front or back of the sample slide is almost directly washed by a water tap. The utility model provides a pair of sample slide washs box has both simulated the actual work in, the manual mode that washs the sample slide of medical staff is superior to manual washing again, simple structure, adopts and openly washes and soak the mode that washs and combine together with the sample slide back to the sample slide, makes the sample slide wash cleaner.
In this embodiment, the sample slide 10 is vertically inserted into the cleaning cavity 5 by the scheduling mechanism, wherein the bottom edge of the sample slide 10, which is far away from the printing end, is vertically inserted and placed in the cleaning cavity 5 in a direction toward the bottom of the cleaning cavity 5, the front surface of the sample slide 10 faces one side of the cleaning injection channel 1, the cleaning solution is injected from the cleaning injection channel 1 communicated with the inside of the cleaning cavity 5 to wash the front surface of the sample slide 10, and meanwhile, the liquid is pumped from the negative pressure pumping channel 2 at the bottom of the cleaning cavity 5 to clean the staining residues attached to the blood film of the sample slide 10, and certainly, the cleaning solution can be injected into the cleaning cavity 5 to soak and clean, so that the front surface of the sample slide and the back surface of the sample slide are both cleaned more cleanly. Because the staining residues are more easily adhered to the blood film, the front surface of the sample slide 10 is cleaned by a simulation faucet, and the back surface of the sample slide 10 is smooth, has no blood film and is not easily adhered to the staining residues, so that the back surface of the sample slide 10 can be cleaned by a liquid pumping mode after soaking without separately cleaning the back surface, the structure is simpler, the control is simpler, and the cleaning is cleaner.
More specifically, as shown in fig. 2, the cleaning cavity 5 is a cavity structure surrounded by four circumferential side walls and 1 bottom wall, preferably, a rectangular parallelepiped structure. The four circumferential side walls are respectively a first side wall 511 communicated with the cleaning liquid injection channel 1, a second side wall arranged opposite to the first side wall 511, a third side wall 531 arranged adjacent to the first side wall 511 and a fourth side wall arranged opposite to the third side wall 531; the bottom wall is located at the bottom of the washing chamber 5. The design of the structure is convenient for processing, the surface of the third side wall 531 or the fourth side wall is not provided with any protruding structure, and the flat plate type side wall structure can ensure that the sample slide cleaning box is used for positioning when being installed, so that the Z-axis rotation deviation of the sample slide cleaning box after being installed is avoided, and the positioning adjustment of the scheduling mechanism in the motion direction is further realized.
As shown in fig. 2 and 3, in a preferred embodiment, a guide portion 6 is further disposed in the cleaning chamber 5, and the guide portion 6 is used for guiding and stabilizing the sample slide 10 accommodated in the cleaning chamber 5. The guide portions 6 are respectively disposed at one side of the third sidewall 531 and the fourth sidewall adjacent to the first sidewall 511 of the cleaning chamber 5, and the guide portions 6 are respectively connected to at least one of the first sidewall 511, the second sidewall, the third sidewall 531 and the fourth sidewall. In a more preferred embodiment, as shown in fig. 3, the guide portions 6 on each side include a first guide portion 61 and a second guide portion 62, and the first guide portion 61 and the second guide portion 62 are not continuously provided. In the present embodiment, the first guide portion 61 and the second guide portion 62 are coaxially arranged in the vertical direction, i.e., are arranged at intervals in the Z-axis direction shown in fig. 2, and the first guide portion 61 is above the second guide portion 62 in the Z-axis direction. As shown in fig. 4, the sample slide 10 is inserted into the cleaning chamber 5 through the first guide portion 61 and the second guide portion 62, the inside of the cleaning chamber 5 is divided into two regions, namely, the cleaning region 54 and the stain accumulation region 55, by the front and back surfaces of the sample slide 10, the first guide portion 61 and the second guide portion 62 are discontinuously arranged, so that the resistance of the water flow flowing in the cleaning chamber 5 is smaller, and the water can flow into the stain accumulation region 55 from the cleaning region 54 more rapidly, the drainage flow rate of the cleaning region 54 is increased, and the stains are accumulated in the stain accumulation region 55 rapidly.
It should be understood that the guide portion 6 may be configured to guide the side surface of the sample slide 10 in the width direction, and the guide portion 6 may be configured in other ways to guide the sample slide 10, which is not limited in this embodiment.
More preferably, the guiding portions 6 on the third side wall 531 and the guiding portions 6 on the fourth side wall may be symmetrically disposed or may be staggered up and down.
Further, as shown in fig. 3, the first guide portion 61 includes a first insertion slot 611 for guiding; the second guide portion 62 includes a second insertion port 621 for guiding; the first insert pocket 611 and the second insert pocket 621 are coaxially disposed. The coaxial arrangement of the first insert opening 611 and the second insert opening 621 can ensure that the sample slide 10 is guided by the insert openings of the first guide portion 61 and the second guide portion 62 when inserted, and can ensure that the sample slide 10 is more stable when placed. More specifically, a bottom carrier 63 may also be provided within the washing chamber 5 for supporting the sample slide 10. The bottom bearing part 63 can further comprise a third insert notch 631 for guiding and a support platform for supporting the sample slide 10, the third insert notch 631, the first insert notch 611 and the second insert notch 621 are coaxially arranged, wherein the opening diameter of the first insert notch 611 is smaller than that of the second insert notch 621, and the opening diameter of the third insert notch 631 is smaller than that of the second insert notch 621, it can be understood that the channel diameters of the 3 insert notches for fixing the sample slide 10 are the same, and by such design, the sample slide 10 can be ensured to be smoothly inserted into the first guide part 61, the second guide part 62 and the bottom bearing part 63 in sequence, the reliability of the sample slide washing box and the stability of the sample slide 10 when being washed can be ensured, and the cleaning quality and the cleaning efficiency of the sample slide 10 can be indirectly ensured.
More preferably, as shown in fig. 2 and 3, the main body of the first guide portion 61 is connected to the first side wall 511 and the second side wall in the Y-axis direction, a first insertion opening 611 is opened in the main body of the first guide portion 61, the first insertion opening 611 penetrates through the main body of the first guide portion 61 in the Z-axis direction, the width of the first insertion opening 611, that is, the opening degree of the first insertion opening 611 in the Y-axis direction is slightly larger than the thickness of the sample slide, and the first guide portion 61 on the third side wall 531 side and the fourth side wall side respectively guides the left and right side surfaces of the sample slide 10 in the width direction. The first guide part 61, the first side wall 511 and the second side wall enclose a cleaning cavity opening 51; the first tab opening 611 does not penetrate the main body of the first guide portion 61 in the X-axis direction, and the surfaces of the main body of the first guide portion 61 near the third side wall 531 or the fourth side wall respectively enclose the vent holes 53 with the third side wall 531 and the fourth side wall. The second guide portion 62 and the bottom bearing portion 63 are similar to the first guide portion 61, and are not described in detail here.
In a more preferred embodiment, as shown in fig. 2, 2 cleaning liquid injection channels 1 can be provided, including a first cleaning liquid injection channel and a second cleaning liquid injection channel, and the first cleaning liquid injection channel and the second cleaning liquid injection channel are arranged side by side at the same horizontal height. After the washing liquid is injected from the washing liquid injection channel 1, it impinges on the washing liquid impact point 8 on the sample slide 10, and then the water spreads all around, as indicated by the arrows in fig. 5. It can be understood that, so set up can guarantee rivers at reasonable pressure range, do not destroy the blood film on the sample slide again, can make the blood film face scope of the sample slide that washes again wider, the washing is cleaner.
Further, as shown in fig. 4, the injection direction of the cleaning liquid into the cleaning liquid injection channel 1 is inclined toward the bottom of the cleaning chamber 5, and the included angle β between the central line of the sample slide 10 accommodated in the cleaning chamber 5 is 30 ° to 45 °. The cleaning water flow is prevented from rising upward and overflowing the cleaning orifice 51.
In a preferred embodiment, an overflow cavity 4 is further connected to the second side wall, and the overflow cavity 4 is arranged outside the second side wall, i.e. on the side away from the first side wall. The bottom of the overflow cavity 4 is provided with a natural overflow port 3, the overflow cavity 4 is used for accommodating redundant liquid in the cleaning cavity 5, and an overflow port 52 is further formed in the cleaning cavity 51 on the second side wall. Excess liquid in the cleaning chamber 5 can flow into the overflow chamber 4 through the overflow port 52 and then be discharged through the natural overflow port 3 at the bottom. By the design, the overflow liquid can be buffered and buffered.
Because the cleaning liquid surface tension is large, a concave water surface is formed at the overflow port 52, so that the overflow water level is raised, the lower overflow port is arranged, the overflow sectional area can be increased, the raised water level of the concave water surface is compensated, and stable overflow is formed.
More specifically, when the sample slide 10 is inserted and placed vertically in a direction from the bottom edge of the printing end to the bottom of the cleaning chamber 5, the distances between the sample slide 10 accommodated in the cleaning chamber 5 and the four circumferential side walls and 1 bottom wall of the cleaning chamber 5 are all greater than 0. More specifically, as shown in fig. 5, the sample slide 10 is stably accommodated in the cleaning chamber 5 through the first insertion opening 611 of the first guide portion 61, the second insertion opening 621 of the second guide portion 62, the third insertion opening 631 of the bottom bearing portion 63, and the support platform of the bottom bearing portion 63, and the distances between the sample slide 10 accommodated in the cleaning chamber 5 and the four circumferential side walls and 1 bottom wall of the cleaning chamber 5 are all greater than 0. With this arrangement, in addition to the front and back surfaces of the sample slide 10 being spaced apart from the circumferential side wall of the cleaning chamber 5, the side surface of the sample slide 10 in the width direction accommodated in the cleaning chamber 5 has a gap (i.e., a small region 11) with the respective adjacent third and fourth side walls 531 and 531, and the bottom edge of the sample slide 10 away from the printing end also has a gap with the bottom wall of the cleaning chamber 5. After the cleaning solution has hit sample slide 10, along sample slide 10 surface to dispersing all around, the clearance on both sides has increased the space of rivers about sample slide 10 width direction for rivers are more unobstructed, can make the more smooth and easy follow washing zone 54 inflow staining sediment gathering zone 55 of cleaning solution, and the cleaning performance is better.
Further, as shown in fig. 4, the first sidewall 511The distance between the sample slide 10 and the cleaning chamber 5 is a first distance l 1 The distance between the second side wall and the sample slide 10 housed in the washing chamber 5 is a second distance l 2 Wherein the first distance l 1 And a second distance l 2 The ratio range between is 1: 1.5-1: 3. more specifically, the ratio range may also be 1. Reduce and wash regional 54 volume, increase the volume of staining sediment gathering region 55, can increase rivers to the impact force of the blood film face of sample slide 10, let the more clean that the staining sediment was washed, make rivers from the less regional 54 fast migration of washing of volume to the great staining sediment gathering region 55 of volume, slow down the water velocity in staining sediment gathering region 55, thereby can make the staining sediment gather in staining sediment gathering region 55 as far as, thereby be convenient for take out, make the staining sediment wash cleaner.
In a preferred embodiment, as shown in fig. 2 and 6, the cleaning cavity 5 further includes an air vent 53, the air vent 53 is adjacent to the outside of the cleaning cavity 51, and the air vent 53 is surrounded by the outer wall of the main body of the guide portion and the third side wall 531 or the fourth side wall of the cleaning cavity 5 and communicates with the inside of the cleaning cavity 5. As shown in fig. 8, when the amount of the overflow port 52 is unable to keep up with the liquid discharge amount due to excessive injection of the cleaning liquid or other failures, the overflowed cleaning liquid can flow back into the cleaning chamber 5 through the vent hole 53 from the gap between the cleaning cassette mounting plate MP and the specimen slide cleaning cassette CB, and the auxiliary liquid discharge function is performed.
The vent hole 53 also has a function of assisting air discharge, and when the cleaning liquid in the cleaning chamber 5 is injected toward the front surface of the slide specimen 10 and the cleaning liquid flows toward the small region 11 on both sides of the third or fourth side wall of the guide portion 6 (i.e., the space between the side surface of the slide specimen 10 in the width direction and the third or fourth side wall), the small region 11 is connected to the atmosphere, and the cleaning liquid is kept flowing more smoothly toward the small region 11 after injection.
In a more preferred embodiment, as shown in fig. 3 to 5, a cleaning solution guiding surface 7 is further disposed in the cleaning cavity 5, and the cleaning solution guiding surface 7 is disposed at the inner side of the bottom of the cleaning cavity 5. The cleaning solution flow guide surface 7 is arranged on the first side wall, namely the side wall where the cleaning solution injection channel is located inclines towards the bottom wall of the cleaning cavity 5 from the opposite side (namely towards the back of the sample slide 10) of the cleaning solution injection channel 1; the negative pressure liquid pumping channel 2 is arranged at the lowest point of the cleaning liquid guide surface 7 and is communicated with the inside of the cleaning cavity 5.
The existence of the cleaning liquid guide surface 7 can enable cleaning liquid at the bottom of the cleaning cavity 5 to be gathered in the staining slag gathering area 55 and be pumped away by the negative pressure liquid pumping channel 2, and on the other hand, the staining slag can be gathered at the bottom of the staining slag gathering area 55 in a vortex mode and then be pumped away quickly by the negative pressure liquid pumping channel 2, so that the cleaning is cleaner, and the staining slag is not easy to suspend in the front direction of the sample slide 10.
The cleaning solution guide surface 7 inclines towards the bottom wall of the cleaning cavity 5 towards the back surface of the sample slide 10 and is in clearance fit with the four side walls and the bottom wall of the sample slide 10, so that water flow can quickly diffuse and discharge the flushed staining residues to the staining residue gathering area 55, and the staining residue cleaning rate of the blood film area of the sample slide 10 is improved.
In a more preferred embodiment, the flow guiding surface of the cleaning solution flow guiding surface 7 may be an arc surface, or may also be a plane, and both the arc surface and the plane are inclined toward the back surface of the sample slide 10 and the bottom wall of the cleaning cavity 5, which may be specifically selected according to the actual situation, and this embodiment does not limit this.
As shown in fig. 7 and 8, the second aspect of the present invention further provides a piece pushing and dyeing machine, including: the smear module is used for preparing the blood film smear, the staining module is used for staining the blood film smear, and the sample slide cleaning box of any one or any combination of the above modules is used for cleaning the blood film smear.
In a preferred embodiment, the dyeing module further comprises a washing tank, a dyeing tank and a fixed tank; the sample slide cleaning box is detachably placed in the cleaning groove; the cleaning tank is arranged in parallel with the dye solution tank and the fixed solution tank.
The utility model discloses a push away and dye mascerating machine possesses the utility model discloses a sample slide washs all beneficial effects of box.
[ one of application scenarios ]
As shown in fig. 7, there are a sample slide cleaning box CB, a cleaning bath GC in which the sample slide cleaning box CB is placed, a dye bath GD, and a fixed bath GH. The difference between fig. 8 and 7 is that a mounting plate MP is mounted on the notch of the cleaning bath GC. In the application scenario, the fixed liquid bath GH, the dye bath GD and the cleaning bath GC are arranged in parallel along a first direction, a plurality of sample slide cleaning boxes CB are arranged in the cleaning bath GC along a second direction, the sample slide cleaning boxes CB are fixed on the mounting plate MP through mounting positions arranged on the top ends of the third side wall 531 and the fourth side wall, and are then arranged in the cleaning bath GC together with the mounting plate MP, the mounting plate MP can cover the notch of the cleaning bath GC, and an opening of the overflow cavity 4 of the sample slide cleaning box CB and a reserved opening of the cleaning cavity opening 51 are reserved on the mounting plate MP.
< method of Using specimen slide washing Box >
The cleaning liquid flows in from the cleaning liquid injection channel 1 and is pumped away from the negative pressure liquid pumping channel 2, and the overflowed liquid is discharged from the natural overflow port 3. The sample slide 10 is inserted into the cleaning cavity 5 through the first insertion port 611 by the gripper, and the front surface of the sample slide 10 faces the side of the cleaning injection channel 1. After the sample slide 10 is inserted into the washing chamber 5, the interior of the washing chamber 5 is divided into a washing area 54 having a small volume and a stain collecting area 55 having a large volume, and the sample slide 10 is cleaned by a combination of washing and soaking.
Because the staining residues are more easily adhered to the blood membrane, and the back surface of the sample slide 10 is smooth and has no blood membrane and is not easily adhered to the staining residues, the front surface of the sample slide 10 is cleaned through a simulation faucet, the back surface of the sample slide 10 can be cleaned in a liquid drawing mode after being soaked, and the back surface is not separately cleaned, so that the structure is simpler, the control is simpler, and the cleaning is cleaner.
Based on the sample slide cleaning box provided by the embodiment, the embodiment also provides a slide pushing and dyeing machine, which comprises a smear module and a dyeing module; the smear module is used for preparing a blood film smear; the staining module is used for staining the blood film smear; the sample slide cleaning box in the embodiment is also included and is used for cleaning the stained blood film smear.
Further, as shown in fig. 7-8, the dyeing module further includes a washing tank GC, a fixed tank GH, and a dyeing tank GD; the sample slide cleaning box CB is detachably placed in a cleaning groove GC; the cleaning tank is arranged in parallel with the fixed liquid tank GH and the dye liquid tank GD. Compact structure, easy to assemble can form the sample slide that is the matrix form overall arrangement in whole dyeing module and insert the position, can reduce the volume of whole dyeing module.
Since the sample slide cleaning box provided by the embodiment has the technical effects, and the push staining machine comprises the sample slide cleaning box, the push staining machine also has corresponding technical effects, and the details are not repeated herein.
The above description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (17)
1. The utility model provides a sample slide washs box, its characterized in that, sample slide washs box including wash the cavity and with wash the washing notes liquid passageway that the cavity internal portion communicates, wherein, wash the cavity and be used for holding vertical male sample slide, just the sample slide scribbles the one side orientation of blood film wash notes liquid passageway, it sets up to wash notes liquid passageway wash on the first lateral wall of cavity for pour into the washing liquid into in the cavity to wasing the sample slide washes.
2. The specimen slide cleaning cassette according to claim 1, wherein a guide portion is provided in the cleaning chamber, the guide portion including a guide insertion opening through which a specimen slide passes to guide and stabilize the specimen slide accommodated in the cleaning chamber.
3. The specimen slide cleaning cassette according to claim 1, wherein a negative pressure liquid suction channel is provided at a bottom of the cleaning chamber to discharge a waste liquid after cleaning.
4. The specimen slide cleaning box of claim 1, wherein an overflow cavity is disposed on a second side wall opposite to the first side wall where the cleaning liquid injection channel is disposed, the overflow cavity is disposed on a side of the second side wall away from the first side wall, an overflow port is disposed on the second side wall to allow excess liquid in the cleaning cavity to overflow to the overflow cavity through the overflow port, and a natural overflow port is disposed at the bottom of the overflow cavity.
5. The specimen slide washing cassette according to claim 2, wherein the guide portions are respectively provided at a side of a third side wall and a fourth side wall adjacent to a first side wall of the washing chamber, and the guide portions are respectively connected to at least one of the first side wall, the second side wall, the third side wall, and the fourth side wall, wherein the guide portion at each side includes a first guide portion including a first insertion opening for guiding and a second guide portion including a second insertion opening for guiding; the first inserting piece opening and the second inserting piece opening are coaxially arranged along the vertical direction.
6. The specimen slide washing cassette according to claim 5, wherein the first guide portion and the second guide portion are coaxially arranged in a vertical direction, and the first guide portion and the second guide portion are discontinuously arranged.
7. The specimen slide cleaning cassette of claim 5 or 6, wherein the first guide portions are connected to the first and second side walls, respectively, and the second guide portions are connected to the first and second side walls, respectively.
8. The specimen slide cleaning cassette of claim 7, wherein a bottom carrying portion for supporting the specimen slide is further disposed in the cleaning cavity, the bottom carrying portion includes a third insertion opening for guiding, the third insertion opening is coaxially disposed with the second insertion opening and the first insertion opening, respectively, wherein an opening diameter of the first insertion opening is smaller than an opening diameter of the second insertion opening, and an opening diameter of the third insertion opening is smaller than an opening diameter of the second insertion opening.
9. The specimen slide cleaning cartridge according to claim 1, wherein the cleaning liquid injection direction of the cleaning liquid injection channel is inclined toward the bottom of the cleaning chamber, and an angle with a center line of the specimen slide accommodated in the cleaning chamber is in a range of 30 ° to 45 °.
10. The specimen slide cleaning cassette of claim 1, wherein the cleaning priming channel includes a first cleaning priming channel and a second cleaning priming channel, the first cleaning priming channel and the second cleaning priming channel being disposed side-by-side at a same level.
11. The sample slide cleaning cartridge of claim 1, wherein the distance between each of the circumferential side and bottom walls of the cleaning chamber and the sample slide received in the cleaning chamber is greater than 0.
12. The specimen slide washing cassette according to claim 1, wherein a distance between the first side wall and the specimen slide accommodated in the washing chamber is a first distance, a distance between a second side wall opposite to the first side wall where the washing liquid injection channel is located and the specimen slide accommodated in the washing chamber is a second distance, and wherein a ratio between the first distance and the second distance ranges from 1: 1.5-1: 3.
13. the specimen slide washing cassette according to claim 2, wherein the washing chamber further includes vent holes respectively provided at both sides of the washing chamber where the guide portion is located, respectively surrounded by a third side wall and a fourth side wall of the main body of the guide portion adjacent to the first side wall of the washing chamber, and communicating with the inside of the washing chamber.
14. The specimen slide cleaning box according to claim 3, wherein a cleaning solution guide surface is further disposed in the cleaning cavity, the cleaning solution guide surface is disposed inside a bottom of the cleaning cavity, the cleaning solution guide surface faces an opposite side of the cleaning solution injection channel and is inclined toward the bottom of the cleaning cavity, and the negative pressure solution suction channel is disposed at a lowest point of the cleaning solution guide surface.
15. The specimen slide cleaning cassette of claim 14, wherein the flow directing surface of the cleaning solution flow directing surface is a curved surface or a flat surface.
16. A piece pushing and dyeing machine, which is characterized in that,
the method comprises the following steps:
the smear module is used for preparing a blood film smear;
the staining module is used for staining the blood film smear;
further comprising at least one specimen slide washing cassette according to any one of claims 1 to 14 for washing a blood film smear.
17. The slide dyeing machine of claim 16,
the dyeing module also comprises a washing tank, a dye solution tank and a fixed solution tank;
the sample slide cleaning box is detachably placed in the cleaning groove;
the cleaning tank is arranged in parallel with the dye solution tank and the fixed solution tank.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2021234067819 | 2021-12-31 | ||
| CN202123406781 | 2021-12-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN218157177U true CN218157177U (en) | 2022-12-27 |
Family
ID=84421761
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202222053624.2U Active CN218157177U (en) | 2021-12-31 | 2022-08-04 | Sample slide cleaning box and slide pushing and dyeing machine |
| CN202210933908.2A Pending CN115479828A (en) | 2021-12-31 | 2022-08-04 | Sample slide cleaning box and slide pushing and dyeing machine |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210933908.2A Pending CN115479828A (en) | 2021-12-31 | 2022-08-04 | Sample slide cleaning box and slide pushing and dyeing machine |
Country Status (1)
| Country | Link |
|---|---|
| CN (2) | CN218157177U (en) |
-
2022
- 2022-08-04 CN CN202222053624.2U patent/CN218157177U/en active Active
- 2022-08-04 CN CN202210933908.2A patent/CN115479828A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN115479828A (en) | 2022-12-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN218157177U (en) | Sample slide cleaning box and slide pushing and dyeing machine | |
| CN111751193B (en) | Glass slide upright semi-immersion fixed type constant-temperature dyeing bin unit and dyeing machine | |
| CN217565192U (en) | Cleaning device | |
| CN211401881U (en) | Batch slide staining rack | |
| CN214373754U (en) | Glycogen dyeing box | |
| CN215677791U (en) | Dyeing box for base liquid cells | |
| CN215179066U (en) | Wet box convenient to waste liquid treatment | |
| CN207964419U (en) | A kind of ring dyeing device | |
| CN210586216U (en) | A wash pond for immunohistochemical dyeing machine | |
| CN216870148U (en) | Slide glass storage box and dyeing device | |
| CN208505730U (en) | A kind of slide placement frame suitable for overflow dyeing machine | |
| CN220893922U (en) | Blood smear dye vat and blood smear dyeing apparatus | |
| CN213121328U (en) | Slice making bottle integrating slice making, drying and dyeing | |
| CN216727319U (en) | Test kit convenient to contrast | |
| CN220691972U (en) | Semiconductor chemical cleaning tank | |
| CN213022435U (en) | A liquid medicine sampling device for pharmaceutical analysis | |
| CN218298661U (en) | Multi-groove dyeing glass slide assembly | |
| CN113419338B (en) | Universal coupling groove for imaging of light sheet and structured light microscope | |
| CN219059962U (en) | Water conservancy gate | |
| CN216117021U (en) | Dyeing container, dyeing device and push piece dyeing machine | |
| CN212988984U (en) | Waste liquid water conservancy diversion slide frame that bacterium gram staining used | |
| CN220126247U (en) | Optimize fluid infusion equipment | |
| CN218455698U (en) | Novel water quality analyzer circulation cup | |
| CN211668148U (en) | Cuvette airing rack | |
| JP5872776B2 (en) | Cell assay channel chip and inspection device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |